Page last updated: 2024-09-04

methylisopropylamiloride and amiloride

methylisopropylamiloride has been researched along with amiloride in 7 studies

Compound Research Comparison

Studies
(methylisopropylamiloride)
Trials
(methylisopropylamiloride)
Recent Studies (post-2010)
(methylisopropylamiloride)
Studies
(amiloride)
Trials
(amiloride)
Recent Studies (post-2010) (amiloride)
7007,584339788

Protein Interaction Comparison

ProteinTaxonomymethylisopropylamiloride (IC50)amiloride (IC50)
Urokinase-type plasminogen activatorHomo sapiens (human)4.7
Urokinase-type plasminogen activatorMus musculus (house mouse)2.3
Amine oxidase [flavin-containing] AHomo sapiens (human)3.909
Sodium/hydrogen exchanger 1Rattus norvegicus (Norway rat)1
Amiloride-sensitive sodium channel subunit alphaHomo sapiens (human)0.776
Sodium/hydrogen exchanger 2Oryctolagus cuniculus (rabbit)1
Acid-sensing ion channel 3Homo sapiens (human)4.4

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19904 (57.14)18.7374
1990's1 (14.29)18.2507
2000's2 (28.57)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cragoe, EJ; Mandel, LJ; Soltoff, SP1
Allemand, D; Ciapa, B; Payan, P1
Becker, JH; Cragoe, EJ; O'Donnell, ME1
Cook, JS; Cragoe, EJ; Shaffer, C1
Marshansky, V; Vinay, P1
Cole, TS; Liedtke, CM1
Cook, DI; Day, ML; Gibb, CA; Harding, EA; Johnson, MH1

Other Studies

7 other study(ies) available for methylisopropylamiloride and amiloride

ArticleYear
Amiloride analogues inhibit proximal tubule metabolism.
    The American journal of physiology, 1986, Volume: 250, Issue:5 Pt 1

    Topics: Adenine Nucleotides; Amiloride; Animals; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; Ion Channels; Kidney Tubules, Proximal; Nystatin; Ouabain; Oxygen Consumption; Rabbits; Sodium; Sodium-Potassium-Exchanging ATPase

1986
Effect of the phorbol ester 12-O-tetradecanoylphorbol-13-acetate (TTPA) upon membrane ionic exchanges in sea urchin eggs.
    Experimental cell research, 1989, Volume: 185, Issue:2

    Topics: Amiloride; Animals; Biological Transport, Active; Calcimycin; Carrier Proteins; Cell Membrane; Female; Hydrogen-Ion Concentration; Kinetics; Male; Ouabain; Ovum; Rubidium; Sea Urchins; Signal Transduction; Sodium; Sodium-Hydrogen Exchangers; Sperm-Ovum Interactions; Tetradecanoylphorbol Acetate; Zygote

1989
Inhibition of Na+ flux in Chinese hamster ovary cells and Swiss 3T3 cells by a potent new derivative of amiloride, methylisopropyl-amiloride.
    The Journal of pharmacology and experimental therapeutics, 1986, Volume: 237, Issue:3

    Topics: Amiloride; Animals; Biological Transport; Blood Physiological Phenomena; Cells, Cultured; Cricetinae; Cricetulus; Depression, Chemical; Dose-Response Relationship, Drug; Female; Melitten; Nigericin; Ovary; Protons; Sodium

1986
Inhibition by amiloride analogues of Na+-dependent hexose uptake in LLC-PK1/Cl4 cells.
    The American journal of physiology, 1987, Volume: 253, Issue:2 Pt 1

    Topics: Amiloride; Animals; Clone Cells; Dose-Response Relationship, Drug; Hexoses; Kidney; Phlorhizin; Sodium

1987
Proton gradient formation in early endosomes from proximal tubules.
    Biochimica et biophysica acta, 1996, Oct-23, Volume: 1284, Issue:2

    Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Acridine Orange; Adenosine Triphosphate; Amiloride; Animals; Cell Fractionation; Chloride Channels; Chlorides; Dogs; Endosomes; Hydrogen-Ion Concentration; Intracellular Membranes; Kidney Cortex; Kidney Tubules, Proximal; Microvilli; Monensin; Nitrobenzoates; Proton-Translocating ATPases; Sodium-Hydrogen Exchangers; Vacuolar Proton-Translocating ATPases

1996
Activation of NKCC1 by hyperosmotic stress in human tracheal epithelial cells involves PKC-delta and ERK.
    Biochimica et biophysica acta, 2002, Feb-13, Volume: 1589, Issue:1

    Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Amiloride; Bumetanide; Cells, Cultured; Chlorine; Enzyme Activation; Enzyme Inhibitors; Epithelial Cells; Flavonoids; Humans; Mitogen-Activated Protein Kinases; Osmotic Pressure; Protein Kinase C; Rubidium; Sodium Chloride; Sodium-Potassium-Chloride Symporters; Solute Carrier Family 12, Member 2; Sucrose; Trachea

2002
Developmental changes in the management of acid loads during preimplantation mouse development.
    Biology of reproduction, 2002, Volume: 67, Issue:5

    Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Acids; Amiloride; Animals; Blastocyst; Embryonic Development; Female; Guanidines; Hydrogen; Ion Transport; Lithium; Mice; Mice, Inbred Strains; Oocytes; Pregnancy; Protein Isoforms; Sodium-Hydrogen Exchangers; Sulfones; Trophoblasts; Zinc

2002