Page last updated: 2024-09-05

methylinositol and inositol

methylinositol has been researched along with inositol in 127 studies

Compound Research Comparison

Studies (methylinositol)	Trials (methylinositol)	Recent Studies (post-2010) (methylinositol)	Studies (inositol)	Trials (inositol)	Recent Studies (post-2010) (inositol)
137	11	84	8,268	400	2,050

Protein Interaction Comparison

Protein	Taxonomy	inositol (IC50)
Chain B, Pulmonary surfactant-associated protein D	Homo sapiens (human)	5700
Chain A, Pulmonary surfactant-associated protein D	Homo sapiens (human)	5700
Sodium/myo-inositol cotransporter 2	Homo sapiens (human)	104

Research

Studies (127)

Timeframe	Studies, this research(%)	All Research%
pre-1990	7 (5.51)	18.7374
1990's	3 (2.36)	18.2507
2000's	36 (28.35)	29.6817
2010's	51 (40.16)	24.3611
2020's	30 (23.62)	2.80

Authors

Authors	Studies
Beland, GL; Binder, RG; Chan, BG; Dreyer, DL; Hartwig, EE; Waiss, AC	1
Sanz, F; Tarazona, JV	1
Reibach, PH; Streeter, JG	1
Barkla, BJ; Bohnert, HJ; Pantoja, O; Vera-Estrella, R	1
Barkla, BJ; Pantoja, O; Vera-Estrella, R	1
Christiansen, M; Davis, A; Hellerstein, MK; Horowitz, JF; Klein, S; Ostlund, RE	1
Gryff-Keller, A; Horbowicz, M; Lahuta, LB; Szczeciński, P	1
Bailey, CJ; Bates, SH; Jones, RB	1
Falshaw, A; Hart, JB; Tyler, PC	1
Pandey, BL; Pandey, VB; Singh, RK; Tripathi, M	1
Busson, R; Cokelaere, M; Decuypere, E; Flo, G; Holser, R; Leyssen, T; Van Boven, M	1
Stokes, T	1
PLOUVIER, V	2
BILLEK, G; HOFFMANN-OSTENHOF, O; SCHOLDA, R	1
McCOMB, EA; RENDIG, VV	1
Falshaw, A; Falshaw, R; Farkas, E; Hart, JB; Kröger, L; Thiem, J; Win, AL	1
Birge, ZK; Campbell, WW; Fluckey, JD; Haub, MD; Hulver, MW; Morse-Carrithers, H; Ostlund, RE; Thyfault, JP	1
Cha, IJ; Kang, MJ; Kim, JC; Kim, JI; Kim, JJ; Lee, MS	1
Brautigan, DL; Brown, M; Bushweller, JH; Chinigo, G; Grindrod, S; Heimark, DB; Horal, M; Keller, S; Kruszewski, A; Larner, AN; Larner, J; Lukasik, SM; Price, J; Tamura, S	1
Kim, JC; Kim, SH; Kim, YB; Park, RD; Park, SC; Park, SH; Shin, DH; Shin, JY; Shin, YC	1
Jaindl, M; Popp, M	1
Cha, IJ; Kang, MJ; Kim, JC; Kim, JI; Yoon, SY	1
Ashida, H; Kawamura, F; Makino, Y; Morinaga, T; Nanamiya, H; Takahashi, K; Yamaguchi, M; Yoshida, K; Yoshikawa, H	1
Böke, N; Kirmizigül, S; Koz, O; Türkay, E; Uyar, Z; Yaşa, I	1
Choi, IW; Chung, HY; Jeong, YI; Jung, ID; Kim, BH; Kim, JI; Lee, CM; Lee, JS; Park, YM; Seong, EY	1
Chaubal, R; Deshpande, NR; Deshpande, VH; Hebbalkar, GD; Pawar, PV; Puranik, VG; Tungikar, VB	1
Fan, PH; Ji, M; Lou, HX; Ma, YD; Zhan, TR	1
Lou, H; Zhan, T	1
Gupta, P; Lakshmi, V; Srivastava, AK; Tiwari, P	1
Choi, YH; Chung, HY; Jeong, YI; Jung, ID; Lee, CM; Lee, JS; Lee, KS; Lee, SY; Park, YM; Shin, YK; Suh, DS; Yoon, MS	1
Chung, CH; Ha, BW; Kho, JH; Kim, JH; Kim, MJ; Seo, YT; Shin, YG; Yoo, KH	1
Choi, MS; Jeon, SM; Kang, MA; Kwon, EY; Lee, MK; Lee, WH; Park, YB	1
Casanova, J; Castola, V; Duquesnoy, E	1
Buchanan, M; Pullman, GS	1
Aggarwal, BB; Ahn, KS; Sethi, G; Sung, B	1
Cho, CW; Park, CM; Song, YS; Zhou, Y	1
Majumder, AL; Patra, B; Ray, S; Sengupta, S	1
Choi, MS; Do, GM; Jeon, SM; Jung, UJ; Kim, HJ; Lee, MK; Park, YB	1
Campbell, WW; Stull, AJ; Thyfault, JP; Wood, KV	1
Bani, S; Bhat, KA; Gupta, KK; Pandey, A; Shah, BA; Taneja, SC	1
Haraldsson, GG; Järvenpää, E; Jonsdottir, S; Kallio, H; Lassila, M; Yang, B	1
Sivakumar, S; Subramanian, SP	2
Almada, AL; Byars, AG; Campbell, WI; Greenwood, LD; Greenwood, M; Harvey, TM; Kerksick, CM; Kreider, RB; Marcello, BM; Parker, AG; Roberts, MD; Wilborn, CD	1
DUSSY, J; SANNIE, C	1
Palsamy, P; Sivakumar, S; Subramanian, SP	2
Ashida, H; Dang, NT; Mukai, R; Yoshida, K	1
Dzik, T; Lahuta, LB	1
Bani, S; Chauhan, PS; Gupta, KK	1
Karhan, M; Oziyci, HR; Tetik, N; Turhan, I	1
Han, KA; Kim, HJ; Kim, YK; Ku, BJ; Lee, SK; Min, KW; Park, KS	1
Chuang, SM; Liu, SC; Tang, CH	1
Bendayan, R; Kanfer, I; Kis, O; Müller, AC; Patnala, S	1
Bertazza, G; Llanes, A; Luna, V; Palacio, G	1
Apers, S; By, B; Dehaen, W; González Mosquera, DM; Grau Ábalos, R; Hernandez Ortega, Y; Pieters, L; Saucedo Hernandez, Y; Vicet Muro, L	1
Hada, B; Jin, YW; Min, KJ; Myeong, HK; Seong, KM; Yoo, MR	1
Balasubramanian, MP; Nandakumar, N; Rengarajan, T	1
Apers, S; Arcoraci, T; Breynaert, A; Fransen, E; Hermans, N; Kanyanga, C; Magielse, J; Pieters, L; van Dooren, I; Van Hoof, V; Vlietinck, A	1
Chen, CC; Chen, WC; Hsieh, TF; Lee, SS; Lin, TH; Liu, HH; Tan, TW; Tang, CH; Tsai, TH	1
Bañuls, C; Bellod, L; Hernández-Mijares, A; Jover, A; Monzó, N; Peris, JE; Rocha, M; Victor, VM	1
Bhat, KA; Khuroo, MA; Sofi, SN; Taneja, SC; Vishwakarma, R	1
Tetik, N; Yüksel, E	1
Lee, BH; Lee, CC; Wu, SC	1
Ananthan, B; Chang, WC; Li, PH; Lin, JS; Yan, TH	1
Balasubramanian, MP; Haribabu, L; Nandakumar, N; Nishigaki, I; Rajendran, P; Rengarajan, T	1
Balasubramanian, MP; Ganesh, MK; Nandakumar, N; Nishigaki, I; Rajendran, P; Rengarajan, T	1
Bryukhanova, MV; Churakova Sidorova, OV; Kirdyanov, AV; Prokushkin, AS; Rinne, KT; Saurer, M; Siegwolf, RT	1
Bañuls, C; Falcón, R; Hernández-Mijares, A; Monzó, N; Rocha, M; Rovira-Llopis, S; Veses, S; Víctor, VM	1
Cai, H; Gao, Y; Wu, T; Xu, M; Zhang, M; Zhang, Z	1
Srivastava, P; Tiwari, A	1
Ahmad, F; Darokar, MP; Gupta, VK; Khan, F; Misra, L; Prakash, O; Shukla, R	1
Balasubramanian, MP; Lokeshkumar, B; Nandakumar, N; Rajendran, P; Rengarajan, T	1
Cheng, C; Lou, Q; Lu, M; Sun, J; Wang, B; Xu, L; Zhou, F	1
Espartero, JL; Gallego-Fernández, JB; González-Mauraza, NH; León-González, AJ; Martin-Cordero, C; Sánchez-Hidalgo, M	1
Chen, HB; Huang, XM; Li, JG; Wang, HC; Wu, ZC; Yang, ZY	1
Matsumoto, Y; Mukae, SY; Ohashi, T; Ohta, S; Ômura, H	1
Murata, RM; Pereira, LJ; Silva, VO	1
Lin, N; Wu, Y; Xu, Y; Zhang, W; Zhao, Z; Zheng, K	1
Badertscher, R; Burton, KJ; Capozzi, F; Freiburghaus, C; Münger, LH; Picone, G; Pimentel, G; Pralong, FP; Trimigno, A; Vergères, G; Vionnet, N	1
Lou, Q; Lu, M; Sun, J; Wang, B; Wang, S; Xu, L; Zhou, F	1
Abab-Jiménez, Z; Bañuls, C; de Marañón, AM; Gómez-Abril, SÁ; Hernández-Mijares, A; López-Domènech, S; Morillas, C; Rocha, M; Rovira-Llopis, S; Víctor, VM	1
Chang, YS; Chung, S; Hong, YA; Kim, HS; Kim, M; Kim, S; Koh, ES; Park, CW; Shin, SJ	1
Badimon, L; Cubedo, J; Hernández-Mijares, A; Lambert, C; López-Bernal, S; Padró, T; Rocha, M; Vilahur, G	1
Goyal, SN; Mahajan, U; Ojha, S; Patil, CR; Patil, KR; Suchal, K; Vasaikar, N	1
Chagas, RCR; Gomes, INF; Oliveira, BG; Pinto, FE; Reis, RMV; Ribeiro, RIMA; Romão, W; Santos, KM; Silva-Oliveira, RJ	1
Alexander, M; Flores, A; Lakey, JR; Saidian, M; Sathialingam, M; Zhang, S	1
Apers, S; Bijttebier, S; Breynaert, A; Claeys, M; Exarchou, V; Foubert, K; Hermans, N; Pieters, L; Theunis, M; van Dooren, I	1
Ahn, CH; Hossain, MA; Kanth, BK; Lee, E; Park, PB	1
Nematbakhsh, M	1
Agapiou, A; Christou, C; Poulli, E; Yiannopoulos, S	1
Kwon, O; Kwon, SW; Lee, E; Lim, Y	1
Dechorgnat, J; Dumschott, K; Merchant, A	1
Antonowski, T; Górecki, R; Lahuta, L; Osowski, A; Rynkiewicz, A; Wojtkiewicz, J	1
Alba-Betancourt, C; Alonso-Castro, AJ; Gasca-Martínez, D; Pérez-Gutiérrez, S; Rocha-González, E; Ruiz-Arredondo, A; Zapata-Morales, JR	1
Ai, D; Feng, S; Liu, Y; Ma, J; Yang, X	1
Akter, M; Hosokawa, T; Kurasaki, M; Rahaman, MS; Rahman, MM; Saito, T; Sikder, MT	1
An, Y; Fan, M; Li, J; Liu, Y; Tian, W	1
Dong, L; Du, Z; Kong, J	1
Chakrapani, G; Doble, M; Mitra, K; Ravindran, R	1
Cortez, LUAS; Evangelista, JSAM; Fonteles, MC; Heimark, DB; Nascimento, NRF; Santos, CF; Sousa, LGF; Xavier-Júnior, FAF	1
Cimino, F; Cristani, M; Molonia, MS; Occhiuto, C; Palumbo, M; Rocco, C; Ruberto, G; Saija, A; Siracusa, L; Speciale, A	1
Baixeras, E; Decara, J; Fonseca, FR; Gutierrez-Adan, A; Medina-Vera, D; Navarro, JA; Pavón, J; Sanjuan, C; Serrano, A; Suarez, J; Tovar, R; Vida, M	1
Binte Hossain, KF; Hosokawa, T; Kurasaki, M; Rahaman, MS; Saito, T; Yamasaki, S	1
Buszewski, B; Monedeiro, F; Pomastowski, P; Sagandykova, G; Walczak-Skierska, J	1
Cao, K; Fan, Y; Feng, Z; Liu, J; Wang, J; Xu, H	1
Agnelli, F; Del Sole, F; Fittipaldo, VA; Giossi, R; Inglese, E; Menichelli, D; Pani, A; Pintaudi, B; Romandini, A; Roncato, R; Scaglione, F	1
Araujo, TR; Carneiro, EM; Figueiredo, LS; Freitas, IN; Ribeiro, ES; Ribeiro, RA; Silva JÚnior, JAD; Silva, ACVFD	1
Feng, Z; Hu, X; L V, X; Zhu, Y	1
Cheng, M; Fu, CL; Gao, HQ; Li, XL; Xu, M; Yu, F; Yu, X	1
Cai, J; Lin, Y; Su, J; Su, Z; Sun, Z; Wang, M; Wei, L; Wu, X; Wu, Y; Yi, X	1
Baixeras, E; Decara, J; Gutiérrez-Adan, A; Ledesma, JC; Medina-Vera, D; Navarro, JA; Pavón, FJ; Rodríguez de Fonseca, F; Rosell-Valle, C; Sanjuan, C; Tovar, R	1
Chen, Y; Deng, R; Jiang, H; Liu, L; Tian, L; Wu, G; Wu, P; Xu, S	1
Cheng, M; Fu, CL; Li, XL; Xu, M; Yu, F; Yu, X	1
Bosqueiro, JR; de Paula Camaforte, NA; Dokkedal, AL; Marcourt, L; Nejad Ebrahimi, S; Ponce Vareda, PM; Queiroz, EF; Quintiliano Delgado, A; Saldanha, LL; Vilegas, W; Wolfender, JL	1
Cimino, F; Cristani, M; Molonia, MS; Muscarà, C; Occhiuto, C; Ruberto, G; Saija, A; Siracusa, L; Speciale, A	1
Chen, XH; Deng, Y; Lu, L; Tan, Y; Yu, S	1
Kong, J; Li, X; Shi, Y; Sun, X; Tian, J; You, X	1
Azab, A	1
Chen, J; Du, X; Kang, J; Liu, X; Wang, H; Wang, J; Wang, Y; Yang, X	1
Ganguly, A; Kalappan, VM; Lal, V; Pandi, A; Prasad, J; Sattu, K; Varikasuvu, SR	1
Baixeras, E; Decara, J; Gutiérrez-Adán, A; López-Gambero, AJ; Medina-Vera, D; Navarro, JA; Pavón, FJ; Rivera, P; Rodríguez de Fonseca, F; Rosell-Valle, C; Sanjuan, C; Suárez, J; Tovar, R	1
Fujii, T; Kanazawa, N; Matsunaga, C; Ohta, S; Ômura, H; Takatsuka, Y	1
Li, CH; Tien, HJ; Tu, YC; Wen, MF; Yen, HE	1
Koyama, T; Liu, X	1
He, C; Koyama, T; Liu, X	1

Reviews

6 review(s) available for methylinositol and inositol

Article	Year
Towards the production of salt-tolerant crops. Advances in experimental medicine and biology, 1999, Volume: 464 Topics: Aquaporins; Biodegradation, Environmental; Crops, Agricultural; Genetic Engineering; Inositol; Plants; Sodium Chloride	1999
A New Insight of Herbal Promises Against Ocular Disorders: An Occuloinformatics Approach. Current topics in medicinal chemistry, 2016, Volume: 16, Issue:6 Topics: Berberine; Computational Biology; Curcumin; Drug Evaluation, Preclinical; Eye Diseases; Ginkgolides; Herbal Medicine; Humans; Inositol; Models, Molecular; Plants, Medicinal	2016
Health-Promoting Properties of Selected Cyclitols for Metabolic Syndrome and Diabetes. Nutrients, 2019, Sep-30, Volume: 11, Issue:10 Topics: Animals; Biomarkers; Blood Glucose; Cyclitols; Diabetes Mellitus, Type 2; Dietary Supplements; Humans; Hypoglycemic Agents; Inositol; Lipids; Metabolic Syndrome; Treatment Outcome	2019
Inositol and Non-Alcoholic Fatty Liver Disease: A Systematic Review on Deficiencies and Supplementation. Nutrients, 2020, Nov-03, Volume: 12, Issue:11 Topics: Animals; Cholesterol; Dietary Supplements; Female; Glutathione Peroxidase; Humans; Inositol; Insulin Resistance; Lipid Peroxidation; Liver; Male; Non-alcoholic Fatty Liver Disease; Postprandial Period; Randomized Controlled Trials as Topic; Treatment Outcome; Triglycerides	2020
D-Pinitol-Active Natural Product from Carob with Notable Insulin Regulation. Nutrients, 2022, Mar-30, Volume: 14, Issue:7 Topics: Biological Products; Fabaceae; Galactans; Hypoglycemic Agents; Inositol; Insulin; Mannans; Plant Gums	2022
Pharmacological effects of D-Pinitol - A comprehensive review. Journal of food biochemistry, 2022, Volume: 46, Issue:10 Topics: Anti-Inflammatory Agents; Antioxidants; Fabaceae; Glycine max; Inositol; Phytochemicals	2022

Trials

11 trial(s) available for methylinositol and inositol

Article	Year
Effect of pinitol treatment on insulin action in subjects with insulin resistance. Diabetes care, 2000, Volume: 23, Issue:7 Topics: Blood Glucose; Diabetes Mellitus; Diabetes Mellitus, Type 2; Double-Blind Method; Female; Glucose Clamp Technique; Glucose Intolerance; Humans; Hyperinsulinism; Infusions, Intravenous; Inositol; Insulin; Insulin Resistance; Male; Middle Aged; Obesity	2000
Pinitol supplementation does not affect insulin-mediated glucose metabolism and muscle insulin receptor content and phosphorylation in older humans. The Journal of nutrition, 2004, Volume: 134, Issue:11 Topics: Aged; Blood Glucose; C-Peptide; Dietary Supplements; Fasting; Female; Glucose Tolerance Test; Humans; Inositol; Insulin; Male; Middle Aged; Muscle, Skeletal; Phosphorylation; Phosphotyrosine; Placebos; Receptor, Insulin	2004
Effects of pinitol isolated from soybeans on glycaemic control and cardiovascular risk factors in Korean patients with type II diabetes mellitus: a randomized controlled study. European journal of clinical nutrition, 2005, Volume: 59, Issue:3 Topics: Blood Glucose; Cardiovascular Diseases; Cholesterol; Diabetes Mellitus, Type 2; Double-Blind Method; Female; Glycated Hemoglobin; Glycine max; Humans; Inositol; Insulin; Male; Middle Aged; Risk Factors	2005
Effects of acute pinitol supplementation on plasma pinitol concentration, whole body glucose tolerance, and activation of the skeletal muscle insulin receptor in older humans. Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 2009, Volume: 41, Issue:5 Topics: Aged; Blood Glucose; Cross-Over Studies; Double-Blind Method; Female; Glucose; Glucose Tolerance Test; Humans; Inositol; Insulin; Male; Middle Aged; Muscle, Skeletal; Phosphorylation; Receptor, Insulin	2009
The effects of creatine monohydrate supplementation with and without D-pinitol on resistance training adaptations. Journal of strength and conditioning research, 2009, Volume: 23, Issue:9 Topics: Absorptiometry, Photon; Adaptation, Physiological; Adolescent; Adult; Anabolic Agents; Analysis of Variance; Body Composition; Creatine; Dietary Supplements; Double-Blind Method; Drug Therapy, Combination; Exercise Test; Humans; Inositol; Muscle Strength; Resistance Training; Safety; Weight Lifting	2009
Effects of pinitol on glycemic control, insulin resistance and adipocytokine levels in patients with type 2 diabetes mellitus. Annals of nutrition & metabolism, 2012, Volume: 60, Issue:1 Topics: Adipokines; Adiponectin; Adult; Aged; Blood Glucose; C-Peptide; C-Reactive Protein; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Fatty Acids, Nonesterified; Female; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Inositol; Insulin Resistance; Male; Middle Aged; Milk Proteins; Treatment Outcome; Whey Proteins	2012
A single acute dose of pinitol from a naturally-occurring food ingredient decreases hyperglycaemia and circulating insulin levels in healthy subjects. Food chemistry, 2013, Nov-15, Volume: 141, Issue:2 Topics: Adult; Beverages; Blood Glucose; Down-Regulation; Female; Humans; Hyperglycemia; Inositol; Insulin; Male	2013
Chronic consumption of an inositol-enriched carob extract improves postprandial glycaemia and insulin sensitivity in healthy subjects: A randomized controlled trial. Clinical nutrition (Edinburgh, Scotland), 2016, Volume: 35, Issue:3 Topics: Adult; Blood Glucose; Dietary Supplements; Double-Blind Method; Fabaceae; Female; Fruit; Humans; Hyperglycemia; Hyperlipidemias; Hypoglycemic Agents; Hypolipidemic Agents; Inositol; Insulin Resistance; Lipoproteins, IDL; Male; Monitoring, Ambulatory; Particle Size; Plant Extracts; Postprandial Period; Seeds; Spain	2016
Identification of Urinary Food Intake Biomarkers for Milk, Cheese, and Soy-Based Drink by Untargeted GC-MS and NMR in Healthy Humans. Journal of proteome research, 2017, 09-01, Volume: 16, Issue:9 Topics: Adult; Alkaloids; Allantoin; Animals; Biomarkers; Cheese; Cross-Over Studies; Eating; Female; Galactose; Gas Chromatography-Mass Spectrometry; Healthy Volunteers; Hippurates; Humans; Inositol; Lactates; Lactose; Magnetic Resonance Spectroscopy; Male; Metabolome; Milk; Soy Milk	2017
Effects of a Carob-Pod-Derived Sweetener on Glucose Metabolism. Nutrients, 2018, Feb-27, Volume: 10, Issue:3 Topics: Adolescent; Adult; Aged; Animals; Beverages; Blood Glucose; Body Mass Index; Complement C4a; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Disease Models, Animal; Double-Blind Method; Fabaceae; Glucose Intolerance; Glycated Hemoglobin; Healthy Volunteers; Humans; Inositol; Insulin; Insulin-Like Growth Factor I; Male; Middle Aged; Nutritive Sweeteners; Overweight; Plant Extracts; Proteomics; Rats; Rats, Zucker; Young Adult	2018
Pinitol consumption improves liver health status by reducing oxidative stress and fatty acid accumulation in subjects with non-alcoholic fatty liver disease: A randomized, double-blind, placebo-controlled trial. The Journal of nutritional biochemistry, 2019, Volume: 68 Topics: Dietary Supplements; Double-Blind Method; Enzymes; Fatty Acids; Female; Humans; Inositol; Lipids; Liver; Male; Middle Aged; Non-alcoholic Fatty Liver Disease; Oxidative Stress; Postprandial Period	2019

Other Studies

110 other study(ies) available for methylinositol and inositol

Article	Year
Pinitol, a larval growth inhibitor for Heliothis zea in soybeans. Experientia, 1979, Sep-15, Volume: 35, Issue:9 Topics: Animals; Glycine max; Growth Inhibitors; Inositol; Insecticides; Larva; Lepidoptera; Moths; Plants	1979
Toxicity of fractions obtained from the legume species Astragalus lusitanicus Lam. lusitanicus. Toxicon : official journal of the International Society on Toxinology, 1990, Volume: 28, Issue:2 Topics: Animals; Chromatography, Thin Layer; Fabaceae; Flavonoids; Injections, Intravenous; Inositol; Lactones; Mice; Plant Extracts; Plants, Medicinal	1990
Evaluation of active versus passive uptake of metabolites by Rhizobium japonicum bacteroids. Journal of bacteriology, 1984, Volume: 159, Issue:1 Topics: Acetylene; Biological Transport; Biological Transport, Active; Carbon Radioisotopes; Carboxylic Acids; Dextrans; Glucose; Glutamates; Glutamic Acid; Inositol; Insecticides; Kinetics; Malates; Plants; Rhizobium	1984
Salt stress in Mesembryanthemum crystallinum L. cell suspensions activates adaptive mechanisms similar to those observed in the whole plant. Planta, 1999, Volume: 207, Issue:3 Topics: Adaptation, Physiological; Cell Division; Cell Membrane; Cells, Cultured; Hydrolysis; Inositol; Ions; Kinetics; Mannitol; Osmolar Concentration; Plant Physiological Phenomena; Plants; Proton-Translocating ATPases; Sodium Chloride; Vacuolar Proton-Translocating ATPases	1999
Galactosylpinitols isolated from vetch (Vicia villosa roth.) seeds. Journal of agricultural and food chemistry, 2000, Volume: 48, Issue:7 Topics: Fabaceae; Galactosides; Inositol; Magnetic Resonance Spectroscopy; Models, Chemical; Plants, Medicinal; Seeds	2000
Insulin-like effect of pinitol. British journal of pharmacology, 2000, Volume: 130, Issue:8 Topics: Animals; Blood Glucose; Cell Line; Chromones; Deoxyglucose; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Enzyme Inhibitors; Humans; Inositol; Insulin; Mice; Mice, Obese; Morpholines; Muscles; Obesity; Phosphoinositide-3 Kinase Inhibitors; Time Factors	2000
New syntheses of 1D- and 1L-1,2-anhydro-myo-inositol and assessment of their glycosidase inhibitory activities. Carbohydrate research, 2000, Nov-03, Volume: 329, Issue:2 Topics: Aspergillus oryzae; Bacterial Proteins; beta-Galactosidase; beta-Glucosidase; Carbohydrate Conformation; Enzyme Inhibitors; Fungal Proteins; Geobacillus stearothermophilus; Glycoside Hydrolase Inhibitors; Glycoside Hydrolases; Indolizines; Inositol; Magnetic Resonance Spectroscopy; Plant Proteins; Stereoisomerism; Structure-Activity Relationship; Substrate Specificity	2000
Anti-inflammatory effect of (+)-pinitol. Fitoterapia, 2001, Volume: 72, Issue:2 Topics: Animals; Anti-Inflammatory Agents; Carrageenan; Dose-Response Relationship, Drug; Edema; Female; Inositol; Male; Mice; Plant Extracts; Plant Leaves; Plants, Medicinal; Rats; Rats, Wistar	2001
Identification of 4,5-didemethyl-4-O-alpha-D-glucopyranosylsimmondsin and pinitol alpha-D-galactosides in jojoba seed meal (Simmondsia chinensis). Journal of agricultural and food chemistry, 2001, Volume: 49, Issue:9 Topics: Acetonitriles; Animal Feed; Animals; Chromatography, High Pressure Liquid; Cyclohexanes; Galactosides; Glucosides; Growth Inhibitors; Inositol; Magnetic Resonance Spectroscopy; Mass Spectrometry; Silica Gel; Silicon Dioxide; Waxes	2001
AIDS herbal therapy. Trends in plant science, 2002, Volume: 7, Issue:2 Topics: Acquired Immunodeficiency Syndrome; Canavanine; Fabaceae; gamma-Aminobutyric Acid; Humans; Inositol; Phytotherapy; Plant Extracts; South Africa	2002
[The pinitol of Coniferae and the quebrachitol of Aceraceae; search for these compounds in some other families]. Comptes rendus hebdomadaires des seances de l'Academie des sciences, 1953, Jan-19, Volume: 236, Issue:3 Topics: Aceraceae; Inositol; Plants; Taxus	1953
[New research on pinitol in leguminous plants; presence of d-quercitol in Pterocarpus lucens]. Comptes rendus hebdomadaires des seances de l'Academie des sciences, 1955, Dec-14, Volume: 241, Issue:24 Topics: Carbohydrates; Inositol; Plants; Pterocarpus; Research; Sweetening Agents	1955
[INVESTIGATIONS CONCERNING THE BIOSYNTHESIS OF CYCLITOLS, I. FORMATION OF D-PINITOL, D-INOSITOL AND SEQUOYITOL FROM MESO -INOSITOL IN LEAVES OF TRIFOLIUM INCARNATUM]. Hoppe-Seyler's Zeitschrift fur physiologische Chemie, 1964, Volume: 335 Topics: Alcohols; Carbon Isotopes; Chromatography; Cyclitols; Inositol; Photosynthesis; Plant Leaves; Plants; Research; Trifolium	1964
Pinitol (5-O-methyl-D-inositol) as a constituent of Medicago sativa. Archives of biochemistry and biophysics, 1962, Volume: 96 Topics: Inositol; Medicago sativa	1962
Enzyme-catalysed synthesis of galactosylated 1D- and 1L-chiro-inositol, 1D-pinitol, myo-inositol and selected derivatives using the beta-galactosidase from the thermophile Thermoanaerobacter sp. strain TP6-B1. Carbohydrate research, 2004, Aug-02, Volume: 339, Issue:11 Topics: beta-Galactosidase; Carbohydrate Conformation; Carbohydrate Sequence; Catalysis; Galactose; Glycosylation; Inositol; Methylation; Molecular Sequence Data; Stereoisomerism; Thermoanaerobacter	2004
Allosteric activation of protein phosphatase 2C by D-chiro-inositol-galactosamine, a putative mediator mimetic of insulin action. Biochemistry, 2005, Aug-23, Volume: 44, Issue:33 Topics: Amino Acid Substitution; Animals; Binding Sites; Blood Glucose; Chelating Agents; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Activation; Galactosamine; Hydrogen Bonding; Inositol; Inositol Phosphates; Insulin; Male; Manganese; Models, Molecular; Nitrophenols; Organophosphorus Compounds; Phosphoprotein Phosphatases; Point Mutation; Protein Binding; Protein Phosphatase 2C; Protein Structure, Tertiary; Rats; Rats, Sprague-Dawley	2005
Synergistic antiinflammatory effects of pinitol and glucosamine in rats. Phytotherapy research : PTR, 2005, Volume: 19, Issue:12 Topics: Animals; Anti-Inflammatory Agents; Carrageenan; Drug Synergism; Edema; Glucosamine; Granuloma, Foreign-Body; Inositol; Male; Rats; Rats, Sprague-Dawley	2005
Cyclitols protect glutamine synthetase and malate dehydrogenase against heat induced deactivation and thermal denaturation. Biochemical and biophysical research communications, 2006, Jun-30, Volume: 345, Issue:2 Topics: Circular Dichroism; Enzyme Stability; Escherichia coli; Glucose; Glutamate-Ammonia Ligase; History, 17th Century; Hordeum; Hot Temperature; Inositol; Malate Dehydrogenase; Protein Denaturation; Sugar Alcohols; Thermodynamics	2006
Pinitol from soybeans reduces postprandial blood glucose in patients with type 2 diabetes mellitus. Journal of medicinal food, 2006,Summer, Volume: 9, Issue:2 Topics: Blood Glucose; Body Mass Index; Diabetes Mellitus, Type 2; Dietary Carbohydrates; Female; Food; Glycine max; Humans; Hypoglycemic Agents; Inositol; Insulin; Kinetics; Male; Middle Aged; Oryza	2006
Functional myo-inositol catabolic genes of Bacillus subtilis Natto are involved in depletion of pinitol in Natto (fermented soybean). Bioscience, biotechnology, and biochemistry, 2006, Volume: 70, Issue:8 Topics: Bacillus subtilis; Base Sequence; Fermentation; Genes, Bacterial; Glycine max; Inositol; L-Iditol 2-Dehydrogenase; Molecular Sequence Data; Soy Foods	2006
Flavonoid glycosides and methylinositol from Ebenus haussknechtii. Natural product research, 2006, Volume: 20, Issue:11 Topics: Fabaceae; Flavonoids; Glycosides; Inositol; Molecular Structure	2006
D-pinitol regulates Th1/Th2 balance via suppressing Th2 immune response in ovalbumin-induced asthma. FEBS letters, 2007, Jan-09, Volume: 581, Issue:1 Topics: Animals; Asthma; Cytokines; Disease Models, Animal; Eosinophils; Female; GATA3 Transcription Factor; Gene Expression Regulation; Inflammation; Inositol; Lung; Lymphocyte Activation; Mice; Mice, Inbred BALB C; Ovalbumin; Peroxidase; T-Box Domain Proteins; Th1 Cells; Th2 Cells	2007
Larvicidal activity of Acacia nilotica extracts and isolation of D-pinitol--a bioactive carbohydrate. Chemistry & biodiversity, 2005, Volume: 2, Issue:5 Topics: Acacia; Aedes; Animals; Culex; Inositol; Insecticides; Larva; Lethal Dose 50; Models, Molecular; Molecular Structure	2005
Synthesis of 4/5-deoxy-4/5-nucleobase derivatives of 3-O-methyl-D-chiro-inositol as potential antiviral agents. Chemistry & biodiversity, 2006, Volume: 3, Issue:10 Topics: Antiviral Agents; Cell Line, Tumor; Cell Survival; Cytopathogenic Effect, Viral; Humans; Inositol; Models, Molecular; Molecular Structure; Nucleosides; Structure-Activity Relationship	2006
Synthesis of azole nucleoside analogues of D-pinitol as potential antitumor agents. Carbohydrate research, 2007, May-07, Volume: 342, Issue:6 Topics: Antineoplastic Agents; Azoles; Cell Line, Tumor; Cell Survival; Dose-Response Relationship, Drug; Humans; Inositol; Molecular Structure; Nucleosides; Triazoles	2007
Antihyperglycemic activity of Rhizophora apiculata Bl. in rats. Natural product research, 2006, Volume: 20, Issue:14 Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Hypoglycemic Agents; Inositol; Male; Plant Roots; Rats; Rats, Sprague-Dawley; Rhizophoraceae	2006
D-pinitol inhibits Th1 polarization via the suppression of dendritic cells. International immunopharmacology, 2007, Volume: 7, Issue:6 Topics: Animals; Antigens, CD; CD4-Positive T-Lymphocytes; Cells, Cultured; Dendritic Cells; Histocompatibility Antigens Class I; Histocompatibility Antigens Class II; Immunologic Factors; Inositol; Interferon-gamma; Interleukin-12; Male; Mice; Mice, Inbred C57BL; Mitogen-Activated Protein Kinases	2007
Effect of pinitol on glucose metabolism and adipocytokines in uncontrolled type 2 diabetes. Diabetes research and clinical practice, 2007, Volume: 77 Suppl 1 Topics: Adiponectin; Aged; Blood Glucose; C-Reactive Protein; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Fatty Acids, Nonesterified; Female; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Inositol; Leptin; Male; Middle Aged	2007
Effects of soy pinitol on the pro-inflammatory cytokines and scavenger receptors in oxidized low-density lipoprotein-treated THP-1 macrophages. Journal of medicinal food, 2007, Volume: 10, Issue:4 Topics: Cell Line; Chemokine CCL2; Cytokines; Dose-Response Relationship, Drug; Glycine max; Humans; Inositol; Interleukin-1beta; Interleukin-8; Lipids; Lipoproteins, LDL; Macrophages; Matrix Metalloproteinase 9; Receptors, Scavenger; RNA, Messenger; Tumor Necrosis Factor-alpha	2007
Identification and quantitative determination of carbohydrates in ethanolic extracts of two conifers using 13C NMR spectroscopy. Carbohydrate research, 2008, Apr-07, Volume: 343, Issue:5 Topics: Abies; Carbohydrates; Erythritol; Ethanol; Fructose; Glucose; Inositol; Magnetic Resonance Spectroscopy; Mannitol; Molecular Structure; Monosaccharides; Pinus; Plant Extracts; Sugar Alcohols; Tracheophyta	2008
Identification and quantitative analysis of stage-specific carbohydrates in loblolly pine (Pinus taeda) zygotic embryo and female gametophyte tissues. Tree physiology, 2008, Volume: 28, Issue:7 Topics: Carbohydrates; Chromatography, High Pressure Liquid; Fructose; Gas Chromatography-Mass Spectrometry; Glucose; Inositol; Melibiose; Oligosaccharides; Pinus taeda; Raffinose; Seeds; Starch; Sucrose	2008
Pinitol targets nuclear factor-kappaB activation pathway leading to inhibition of gene products associated with proliferation, apoptosis, invasion, and angiogenesis. Molecular cancer therapeutics, 2008, Volume: 7, Issue:6 Topics: Anti-Inflammatory Agents; Apoptosis; Carcinogens; Cell Line, Tumor; Cell Nucleus; Cell Proliferation; DNA, Neoplasm; Dose-Response Relationship, Drug; Enzyme Activation; Humans; I-kappa B Proteins; Inositol; Neoplasm Invasiveness; Neovascularization, Pathologic; NF-kappa B; NF-KappaB Inhibitor alpha; Organ Specificity; Phosphorylation; Protein Binding; Protein Processing, Post-Translational; Protein Transport; Time Factors; Transcription Factor RelA; Tumor Necrosis Factor-alpha	2008
Protective effect of pinitol against D-galactosamine-induced hepatotoxicity in rats fed on a high-fat diet. Bioscience, biotechnology, and biochemistry, 2008, Volume: 72, Issue:7 Topics: Animals; Chemical and Drug Induced Liver Injury; Clinical Enzyme Tests; Galactosamine; Inflammation; Inositol; Lipids; Male; Oxidative Stress; Protective Agents; Rats; Rats, Sprague-Dawley	2008
Inositol methyl tranferase from a halophytic wild rice, Porteresia coarctata Roxb. (Tateoka): regulation of pinitol synthesis under abiotic stress. Plant, cell & environment, 2008, Volume: 31, Issue:10 Topics: Cloning, Molecular; DNA, Complementary; DNA, Plant; Gene Expression Regulation, Plant; Inositol; Methyltransferases; Oryza; Photosynthesis; Plant Proteins; Proteome; Salinity; Sodium Chloride	2008
Metabolic response of soy pinitol on lipid-lowering, antioxidant and hepatoprotective action in hamsters fed-high fat and high cholesterol diet. Molecular nutrition & food research, 2009, Volume: 53, Issue:6 Topics: Animals; Antioxidants; Body Weight; Cholesterol, Dietary; Cricetinae; Dietary Fats; Eating; Glycine max; Hypolipidemic Agents; Inositol; Lipid Peroxidation; Lipids; Liver; Male; Mesocricetus; Organ Size	2009
Semi-synthetic analogs of pinitol as potential inhibitors of TNF-alpha cytokine expression in human neutrophils. Bioorganic & medicinal chemistry letters, 2009, Apr-01, Volume: 19, Issue:7 Topics: Anti-Inflammatory Agents; Gene Expression Regulation; Humans; Inositol; Lipopolysaccharides; Neutrophils; Tumor Necrosis Factor-alpha	2009
Inositols and methylinositols in sea buckthorn (Hippophaë rhamnoides) berries. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2009, May-15, Volume: 877, Issue:14-15 Topics: Chromatography, High Pressure Liquid; Fruit; Gas Chromatography-Mass Spectrometry; Hippophae; Inositol; Plant Extracts	2009
Pancreatic tissue protective nature of D-Pinitol studied in streptozotocin-mediated oxidative stress in experimental diabetic rats. European journal of pharmacology, 2009, Nov-10, Volume: 622, Issue:1-3 Topics: Animals; Antioxidants; Diabetes Mellitus, Experimental; Hyperglycemia; Inositol; Insulin-Secreting Cells; Lipid Peroxidation; Male; Oxidative Stress; Pancreas; Rats; Rats, Wistar; Streptozocin	2009
D-pinitol attenuates the impaired activities of hepatic key enzymes in carbohydrate metabolism of streptozotocin-induced diabetic rats. General physiology and biophysics, 2009, Volume: 28, Issue:3 Topics: Animals; Body Weight; Carbohydrate Metabolism; Diabetes Mellitus, Experimental; Gliclazide; Glucose Tolerance Test; Glycogen; Glycogen Phosphorylase; Glycogen Synthase; Hypoglycemic Agents; Inositol; Liver; Male; Rats; Rats, Wistar	2009
On the presence of pinitol in the leaves of Erythrophleum guineense (G. Don). Comptes rendus hebdomadaires des seances de l'Academie des sciences, 1947, May-12, Volume: 224, Issue:19 Topics: Fabaceae; Inositol	1947
Attenuation of oxidative stress and alteration of hepatic tissue ultrastructure by D-pinitol in streptozotocin-induced diabetic rats. Free radical research, 2010, Volume: 44, Issue:6 Topics: Animals; Antioxidants; Cytokines; Diabetes Mellitus, Experimental; Enzyme-Linked Immunosorbent Assay; Inositol; Liver; Male; Microscopy, Electron, Transmission; Oxidative Stress; Rats; Rats, Wistar; Streptozocin	2010
D-pinitol and myo-inositol stimulate translocation of glucose transporter 4 in skeletal muscle of C57BL/6 mice. Bioscience, biotechnology, and biochemistry, 2010, Volume: 74, Issue:5 Topics: Administration, Oral; Animals; Blood Glucose; Glucose Transporter Type 4; Inositol; Insulin; Male; Mice; Mice, Inbred C57BL; Muscle, Skeletal; Protein Transport; Time Factors	2010
Impact of D-pinitol on the attenuation of proinflammatory cytokines, hyperglycemia-mediated oxidative stress and protection of kidney tissue ultrastructure in streptozotocin-induced diabetic rats. Chemico-biological interactions, 2010, Oct-06, Volume: 188, Issue:1 Topics: Animals; Cytokines; Diabetes Mellitus, Experimental; Hyperglycemia; Inositol; Kidney; Microscopy, Electron, Transmission; Oxidative Stress; Rats; Streptozocin	2010
D-chiro-inositol affects accumulation of raffinose family oligosaccharides in developing embryos of Pisum sativum. Journal of plant physiology, 2011, Mar-01, Volume: 168, Issue:4 Topics: Anti-Bacterial Agents; Antimycin A; Biological Transport; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Disaccharides; Inositol; Oligosaccharides; Pisum sativum; Raffinose; Seeds; Time Factors; Uncoupling Agents	2011
The immunosuppressive effects of Agyrolobium roseum and pinitol in experimental animals. International immunopharmacology, 2011, Volume: 11, Issue:2 Topics: Administration, Oral; Animals; Fabaceae; Immunity, Cellular; Immunity, Humoral; Immunosuppressive Agents; Inositol; Mice; Plant Extracts; Rats; Rats, Wistar	2011
Determination of D-pinitol in carob syrup. International journal of food sciences and nutrition, 2011, Volume: 62, Issue:6 Topics: Dietary Sucrose; Fabaceae; Fructose; Fruit; Galactans; Glucose; Humans; Inositol; Mannans; Mediterranean Region; Plant Gums; Turkey	2011
D-pinitol inhibits RANKL-induced osteoclastogenesis. International immunopharmacology, 2012, Volume: 12, Issue:3 Topics: Animals; Blotting, Western; Bone Marrow Cells; Bone Resorption; Cell Differentiation; Cell Proliferation; Female; Flow Cytometry; Growth Inhibitors; Inositol; Macrophages; MAP Kinase Kinase 4; NF-kappa B; Osteoclasts; Osteogenesis; Osteoporosis; Ovariectomy; p38 Mitogen-Activated Protein Kinases; RANK Ligand; Rats; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction; Stromal Cells; Transfection	2012
Interactions between phytochemical components of Sutherlandia frutescens and the antiretroviral, atazanavir in vitro: implications for absorption and metabolism. Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques, 2012, Volume: 15, Issue:2 Topics: Atazanavir Sulfate; Caco-2 Cells; Canavanine; Fabaceae; gamma-Aminobutyric Acid; Glycosides; HIV Protease Inhibitors; Humans; Inositol; Medicine, African Traditional; Microsomes, Liver; Oligopeptides; Plant Extracts; Pyridines	2012
Different sodium salts cause different solute accumulation in the halophyte Prosopis strombulifera. Plant biology (Stuttgart, Germany), 2013, Volume: 15 Suppl 1 Topics: Carbon; Inositol; Ions; Mannitol; Osmosis; Plant Leaves; Plant Roots; Plant Transpiration; Proline; Prosopis; Salt Tolerance; Salt-Tolerant Plants; Salts; Sodium; Sodium Chloride; Stress, Physiological; Sulfates; Vacuoles; Water	2013
Antihyperglycemic activity of extracts from Boldoa purpurascens leaves in alloxan-induced diabetic rats. Phytotherapy research : PTR, 2013, Volume: 27, Issue:5 Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Hypoglycemic Agents; Inositol; Male; Metformin; Nyctaginaceae; Plant Extracts; Plant Leaves; Rats; Rats, Wistar	2013
D-chiro-inositol and pinitol extend the life span of Drosophila melanogaster. The journals of gerontology. Series A, Biological sciences and medical sciences, 2013, Volume: 68, Issue:3 Topics: Animals; Drosophila melanogaster; Drosophila Proteins; Female; Fertility; Forkhead Transcription Factors; Inositol; Locomotion; Longevity; Male; MAP Kinase Kinase 4; Ribosomal Protein S6 Kinases; Signal Transduction; Starvation; Stress, Physiological	2013
D-Pinitol attenuates 7, 12 dimethylbenz [a] anthracene induced hazards through modulating protein bound carbohydrates, adenosine triphosphatases and lysosomal enzymes during experimental mammary carcinogenesis. Journal of experimental therapeutics & oncology, 2012, Volume: 10, Issue:1 Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenosine Triphosphatases; Animals; Breast; Carcinogens, Environmental; Female; Inositol; Liver; Lysosomes; Mammary Neoplasms, Experimental; Membrane Glycoproteins; Rats; Rats, Sprague-Dawley	2012
Antihepatotoxic activity of a quantified Desmodium adscendens decoction and D-pinitol against chemically-induced liver damage in rats. Journal of ethnopharmacology, 2013, Mar-07, Volume: 146, Issue:1 Topics: Acetaminophen; Alanine Transaminase; Animals; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Ethanol; Fabaceae; Galactosamine; Inositol; Male; Phytotherapy; Plant Extracts; Plant Leaves; Plant Stems; Protective Agents; Rats; Rats, Sprague-Dawley; Rats, Wistar	2013
D-pinitol inhibits prostate cancer metastasis through inhibition of αVβ3 integrin by modulating FAK, c-Src and NF-κB pathways. International journal of molecular sciences, 2013, May-08, Volume: 14, Issue:5 Topics: Antineoplastic Agents; Cell Line, Tumor; CSK Tyrosine-Protein Kinase; Focal Adhesion Kinase 1; Humans; Inositol; Integrin alphaVbeta3; Male; Neoplasm Metastasis; NF-kappa B; Prostate; Prostatic Neoplasms; Signal Transduction; src-Family Kinases	2013
New natural compounds from Rhododendron lepidotum. Natural product research, 2013, Volume: 27, Issue:21 Topics: Inositol; Magnetic Resonance Spectroscopy; Molecular Structure; Oleanolic Acid; Rhododendron	2013
Ultrasound-assisted extraction of D-pinitol from carob pods using Response Surface Methodology. Ultrasonics sonochemistry, 2014, Volume: 21, Issue:2 Topics: Chemical Fractionation; Fabaceae; Inositol; Temperature; Time Factors; Ultrasonics	2014
Ice plant (Mesembryanthemum crystallinum) improves hyperglycaemia and memory impairments in a Wistar rat model of streptozotocin-induced diabetes. Journal of the science of food and agriculture, 2014, Volume: 94, Issue:11 Topics: Acetylcholinesterase; Animals; Avoidance Learning; Blood Glucose; Brain; Cholinesterase Inhibitors; Diabetes Mellitus, Experimental; Hyperglycemia; Hypoglycemic Agents; Inositol; Male; Malondialdehyde; Memory Disorders; Memory, Short-Term; Mesembryanthemum; Mice; Oxidative Stress; Phytotherapy; Plant Extracts; Rats, Wistar; Superoxide Dismutase	2014
A C2-symmetric chiral pool-based flexible strategy: synthesis of (+)- and (-)-shikimic acids, (+)- and (-)-4-epi-shikimic acids, and (+)- and (-)-pinitol. The Journal of organic chemistry, 2014, Apr-04, Volume: 79, Issue:7 Topics: Catalysis; Cyclohexanes; Inositol; Molecular Structure; Shikimic Acid; Stereoisomerism	2014
D-pinitol promotes apoptosis in MCF-7 cells via induction of p53 and Bax and inhibition of Bcl-2 and NF-κB. Asian Pacific journal of cancer prevention : APJCP, 2014, Volume: 15, Issue:4 Topics: Antineoplastic Agents; Apoptosis; bcl-2-Associated X Protein; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Cell Survival; DNA Fragmentation; Female; Gene Expression Regulation, Neoplastic; Glutathione; Glycine max; Humans; Inositol; L-Lactate Dehydrogenase; MCF-7 Cells; Plant Preparations; Proto-Oncogene Proteins c-bcl-2; Transcription Factor RelA; Tumor Suppressor Protein p53	2014
D-pinitol mitigates tumor growth by modulating interleukins and hormones and induces apoptosis in rat breast carcinogenesis through inhibition of NF-κB. Journal of physiology and biochemistry, 2015, Volume: 71, Issue:2 Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Apoptosis; bcl-2-Associated X Protein; Biomarkers, Tumor; Cytokines; Female; Gene Expression Regulation, Neoplastic; Hormones; Immunoglobulins; Inositol; Interleukins; Lipid Metabolism; Mammary Neoplasms, Experimental; NF-kappa B; Rats, Sprague-Dawley	2015
Examining the response of needle carbohydrates from Siberian larch trees to climate using compound-specific δ(13) C and concentration analyses. Plant, cell & environment, 2015, Volume: 38, Issue:11 Topics: Carbohydrate Metabolism; Climate Change; Environment; Fructose; Glucose; Inositol; Larix; Siberia; Sucrose	2015
Effects of D-Pinitol on Insulin Resistance through the PI3K/Akt Signaling Pathway in Type 2 Diabetes Mellitus Rats. Journal of agricultural and food chemistry, 2015, Jul-08, Volume: 63, Issue:26 Topics: Animals; Blood Glucose; Diabetes Mellitus, Type 2; Fabaceae; Glucose Tolerance Test; Glycogen Synthase Kinase 3; Humans; Inositol; Insulin Resistance; Liver; Male; Phosphatidylinositol 3-Kinase; Pinaceae; Plant Extracts; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Signal Transduction	2015
Synergistic effect of (+)-pinitol from Saraca asoca with β-lactam antibiotics and studies on the in silico possible mechanism. Journal of Asian natural products research, 2016, Volume: 18, Issue:2 Topics: Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents; beta-Lactams; Carrageenan; Chromatography, High Pressure Liquid; Edema; Fabaceae; Female; Humans; India; Inositol; Lipopolysaccharides; Medicine, Ayurvedic; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Plant Bark; Rats; Stereoisomerism; Tumor Necrosis Factor-alpha	2016
D-Pinitol Protects Against Carbon Tetrachloride-Induced Hepatotoxicity in Rats. Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer, 2015, Volume: 34, Issue:4 Topics: Animals; Antioxidants; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Disease Models, Animal; Glycine max; Immunohistochemistry; Inositol; Lipid Peroxidation; Liver Function Tests; Male; Rats, Sprague-Dawley	2015
Altered Carbohydrates Allocation by Associated Bacteria-fungi Interactions in a Bark Beetle-microbe Symbiosis. Scientific reports, 2016, Feb-03, Volume: 6 Topics: Animals; Bacteria; Coleoptera; Glucose; Inositol; Larva; Ophiostomatales; Symbiosis	2016
Isolation and Quantification of Pinitol, a Bioactive Cyclitol, in Retama spp. Natural product communications, 2016, Volume: 11, Issue:3 Topics: Fabaceae; Inositol; Molecular Structure	2016
Methyl-inositol, γ-aminobutyric acid and other health benefit compounds in the aril of litchi. International journal of food sciences and nutrition, 2016, Volume: 67, Issue:7 Topics: Amino Acids; Ascorbic Acid; Flavonoids; Fruit; gamma-Aminobutyric Acid; Inositol; Litchi; Phenols	2016
D-Pinitol in Fabaceae: an Oviposition Stimulant for the Common Grass Yellow Butterfly, Eurema mandarina. Journal of chemical ecology, 2016, Volume: 42, Issue:11 Topics: Animals; Butterflies; Fabaceae; Female; Inositol; Oviposition	2016
Oral microbe-host interactions: influence of β-glucans on gene expression of inflammatory cytokines and metabolome profile. BMC microbiology, 2017, 03-07, Volume: 17, Issue:1 Topics: Acetophenones; Aggregatibacter actinomycetemcomitans; Anti-Infective Agents; Benzoic Acid; beta-Glucans; Cell Culture Techniques; Cell Line; Coculture Techniques; Cyclooxygenase 2; Cytokines; E1A-Associated p300 Protein; Fibroblasts; gamma-Aminobutyric Acid; Gene Expression; Host-Pathogen Interactions; Humans; Hydroxybutyrates; Immunomodulation; Inositol; Interleukin-18; Interleukin-1alpha; Keratinocytes; Lymphoma, B-Cell; Metabolome; Mouth; Oxalic Acid; Periodontal Diseases; Proto-Oncogene Proteins c-bcl-2; Real-Time Polymerase Chain Reaction	2017
Protective Effect of Pinitol Against Inflammatory Mediators of Rheumatoid Arthritis via Inhibition of Protein Tyrosine Phosphatase Non-Receptor Type 22 (PTPN22). Medical science monitor : international medical journal of experimental and clinical research, 2017, Apr-21, Volume: 23 Topics: Animals; Antioxidants; Arthritis, Rheumatoid; Cytokines; Disease Models, Animal; Indomethacin; Inflammation Mediators; Inositol; Male; Plant Extracts; Protein Tyrosine Phosphatase, Non-Receptor Type 22; Protein Tyrosine Phosphatases; Rats; Rats, Wistar	2017
Bacterial volatile ammonia regulates the consumption sequence of d-pinitol and d-glucose in a fungus associated with an invasive bark beetle. The ISME journal, 2017, Volume: 11, Issue:12 Topics: Ammonia; Animals; Bacteria; China; Glucose; Inositol; Ophiostomatales; Pinus; Symbiosis; Weevils	2017
Pinitol alleviates systemic inflammatory cytokines in human obesity by a mechanism involving unfolded protein response and sirtuin 1. Clinical nutrition (Edinburgh, Scotland), 2018, Volume: 37, Issue:6 Pt A Topics: Adipose Tissue; Adult; Aged; Anti-Inflammatory Agents; Cytokines; Endoplasmic Reticulum Stress; Female; Humans; Inflammation; Inositol; Leukocytes, Mononuclear; Male; Middle Aged; Obesity; Sirtuin 1; Unfolded Protein Response	2018
D‑Pinitol alleviates cyclosporine A‑induced renal tubulointerstitial fibrosis via activating Sirt1 and Nrf2 antioxidant pathways. International journal of molecular medicine, 2018, Volume: 41, Issue:4 Topics: Animals; Antioxidants; Cyclosporine; Fibrosis; Inositol; Kidney; Kidney Diseases; Kidney Function Tests; Male; Mice, Inbred ICR; NF-E2-Related Factor 2; Oxidative Stress; Sirtuin 1	2018
D-pinitol attenuates cisplatin-induced nephrotoxicity in rats: Impact on pro-inflammatory cytokines. Chemico-biological interactions, 2018, Jun-25, Volume: 290 Topics: Acute Kidney Injury; Animals; Antineoplastic Agents; Catalase; Cisplatin; Creatinine; Cytokines; Glutathione; Inositol; Interleukin-1beta; Interleukin-6; Kidney; Lipid Peroxidation; Male; Mice; Mitogen-Activated Protein Kinases; Oxidative Stress; Superoxide Dismutase; Tumor Necrosis Factor-alpha	2018
BioMed research international, 2018, Volume: 2018 Topics: Apoptosis; Bauhinia; Caspase 3; Cell Death; Cell Line, Tumor; Cell Movement; Cytotoxins; Fatty Acids; HeLa Cells; Humans; Hydroxybenzoates; Inositol; Leukocytes, Mononuclear; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Neoplasm Invasiveness; Plant Extracts; Receptor-Interacting Protein Serine-Threonine Kinases; Receptors, Tumor Necrosis Factor, Type I; Signal Transduction	2018
Evaluation of Cycloferin Supplement on Health Parameters in Experimentally Induced Diabetic Rats with and Without Exogenous Insulin. Journal of dietary supplements, 2019, Volume: 16, Issue:4 Topics: Animals; Blood Glucose; Cyclopia Plant; Diabetes Mellitus, Experimental; Dietary Supplements; Inositol; Insulin; Kidney Diseases; Liver Diseases; Male; Phytotherapy; Plant Extracts; Rats; Rats, Sprague-Dawley; Xanthones	2019
In vitro gastrointestinal biotransformation and characterization of a Desmodium adscendens decoction: the first step in unravelling its behaviour in the human body. The Journal of pharmacy and pharmacology, 2018, Volume: 70, Issue:10 Topics: Apigenin; Biotransformation; Fabaceae; Flavonoids; In Vitro Techniques; Inositol; Models, Theoretical; Molecular Structure; Plant Leaves	2018
Increased salt and drought tolerance by D-pinitol production in transgenic Arabidopsis thaliana. Biochemical and biophysical research communications, 2018, 09-26, Volume: 504, Issue:1 Topics: Arabidopsis; Arabidopsis Proteins; Droughts; Expressed Sequence Tags; Gene Expression Regulation, Plant; Genes, Plant; Glycine max; Inositol; Plants, Genetically Modified; Salt Tolerance; Salts; Seedlings; Sodium Chloride; Stress, Physiological	2018
Re: D-pinitol attenuates cisplatin-induced nephrotoxicity in rats: Impact on proinflammatory cytokines. Chemico-biological interactions, 2018, 12-25, Volume: 296 Topics: Animals; Cisplatin; Cytokines; Inositol; Oxidative Stress; Rats	2018
GC-MS analysis of D-pinitol in carob: Syrup and fruit (flesh and seed). Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2019, May-15, Volume: 1116 Topics: Fabaceae; Fruit; Galactans; Gas Chromatography-Mass Spectrometry; Inositol; Limit of Detection; Linear Models; Mannans; Plant Extracts; Plant Gums; Reproducibility of Results; Seeds	2019
Water Deficit Elicits a Transcriptional Response of Genes Governing d-pinitol Biosynthesis in Soybean ( International journal of molecular sciences, 2019, May-15, Volume: 20, Issue:10 Topics: Droughts; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Plant; Genes, Plant; Glucose; Glucose-6-Phosphate; Glycine max; Inositol; Methyltransferases; Myo-Inositol-1-Phosphate Synthase; Plant Leaves; Plant Proteins; Stress, Physiological; Sucrose; Transcriptome; Water	2019
Neuropharmacological effects of d-pinitol and its possible mechanisms of action. Journal of food biochemistry, 2019, Volume: 43, Issue:12 Topics: Animals; Anti-Anxiety Agents; Anticonvulsants; Antidepressive Agents; Flumazenil; Hypnotics and Sedatives; Inositol; Mice; Mice, Inbred BALB C; Neuropharmacology; Pentylenetetrazole; Seizures; Yohimbine	2019
D-Pinitol Ameliorates Imiquimod-Induced PsoriasisLike Skin Inflammation in a Mouse Model via the NF-κB Pathway. Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer, 2019, Volume: 38, Issue:3 Topics: Animals; Anti-Inflammatory Agents; Imiquimod; Inflammation; Inositol; Male; Mice; Mice, Inbred BALB C; NF-kappa B; Psoriasis	2019
Investigating the protective actions of D-pinitol against arsenic-induced toxicity in PC12 cells and the underlying mechanism. Environmental toxicology and pharmacology, 2020, Volume: 74 Topics: Animals; Arsenic; Autophagy; Cell Survival; Glutathione; Humans; Inositol; PC12 Cells; Protective Agents; Rats	2020
Protective effect of D-pinitol on the experimental spinal cord injury in rats. Metabolic brain disease, 2020, Volume: 35, Issue:3 Topics: Animals; Apoptosis; Inflammation; Inositol; Male; Neuroprotective Agents; NF-kappa B; Oxidative Stress; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley; Recovery of Function; Signal Transduction; Spinal Cord; Spinal Cord Injuries	2020
Pinitol Prevents Lipopolysaccharide (LPS)-Induced Inflammatory Responses in BV2 Microglia Mediated by TREM2. Neurotoxicity research, 2020, Volume: 38, Issue:1 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cells, Cultured; Encephalitis; Inflammation Mediators; Inositol; Lipopolysaccharides; Membrane Glycoproteins; Mice; Microglia; Oxidative Stress; Receptors, Immunologic; Signal Transduction	2020
Inhibitory activity of traditional plants against Mycobacterium smegmatis and their action on Filamenting temperature sensitive mutant Z (FtsZ)-A cell division protein. PloS one, 2020, Volume: 15, Issue:5 Topics: Antitubercular Agents; Bacterial Proteins; Cell Division; Cytoskeletal Proteins; Drug Synergism; Gene Expression Regulation, Bacterial; Genes, Bacterial; Humans; In Vitro Techniques; Inositol; Isoniazid; Microbial Sensitivity Tests; Mutation; Mycobacterium smegmatis; Mycobacterium tuberculosis; Plant Extracts; Plants, Medicinal; Rifampin; Temperature	2020
Renal protective effect of pinitol in experimental diabetes. European journal of pharmacology, 2020, Aug-05, Volume: 880 Topics: Albuminuria; Animals; Creatinine; Diabetes Mellitus, Experimental; Extracellular Signal-Regulated MAP Kinases; Hemodynamics; Hypoglycemic Agents; Inositol; Kidney; Male; Membrane Proteins; Protective Agents; Rats, Wistar; Transforming Growth Factor beta	2020
A pinitol-rich Archives of physiology and biochemistry, 2022, Volume: 128, Issue:5 Topics: Endothelial Cells; Fatty Acids, Nonesterified; Glycyrrhiza; Humans; Inositol; Insulin; Palmitic Acid; Plant Extracts; Polyphenols; Waste Products	2022
D-Pinitol from Nutrients, 2020, Jul-08, Volume: 12, Issue:7 Topics: Administration, Oral; Animals; Depression, Chemical; Fabaceae; Ghrelin; Glucagon; Glycogen; Glycogen Synthase Kinase 3; Glycolysis; Inositol; Insulin Secretion; Liver; Male; Phosphorylation; Proto-Oncogene Proteins c-akt; Pyruvate Kinase; Rats, Wistar	2020
Effects of curcumin, D-pinitol alone or in combination in cytotoxicity induced by arsenic in PC12 cells. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2020, Volume: 144 Topics: Animals; Apoptosis; Arsenic; Autophagy; Cell Membrane; Cell Survival; Curcumin; Flow Cytometry; Glutathione; Inositol; Oxidative Stress; PC12 Cells; Rats	2020
New Methodology for the Identification of Metabolites of Saccharides and Cyclitols by Off-Line EC-MALDI-TOF-MS. International journal of molecular sciences, 2020, Jul-24, Volume: 21, Issue:15 Topics: Cyclitols; Electrochemical Techniques; Inositol; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization	2020
Pinitol attenuates LPS-induced pneumonia in experimental animals: Possible role via inhibition of the TLR-4 and NF-κB/IκBα signaling cascade pathway. Journal of biochemical and molecular toxicology, 2021, Volume: 35, Issue:1 Topics: Animals; Cytokines; Disease Models, Animal; Inositol; Lipopolysaccharides; Male; NF-kappa B; NF-KappaB Inhibitor alpha; Pneumonia; Rats; Rats, Sprague-Dawley; Signal Transduction; Toll-Like Receptor 4	2021
D-Pinitol Increases Insulin Secretion and Regulates Hepatic Lipid Metabolism in Msg-Obese Mice. Anais da Academia Brasileira de Ciencias, 2020, Volume: 92, Issue:4 Topics: Animals; Blood Glucose; Inositol; Insulin Secretion; Lipid Metabolism; Lipids; Mice; Mice, Obese; Sodium Glutamate	2020
Elucidation of the mechanism of action of pinitol against pressure overload-induced cardiac hypertrophy and fibrosis in an animal model of aortic stenosis. Bioscience, biotechnology, and biochemistry, 2021, Feb-24, Volume: 85, Issue:3 Topics: Animals; Cardiomegaly; Disease Models, Animal; Gene Expression Profiling; Heart Function Tests; Inositol; Lisinopril; Mitochondria, Heart; Rats; Rats, Sprague-Dawley; RNA, Messenger; Up-Regulation	2021
Effects of D-pinitol on myocardial apoptosis and fibrosis in streptozocin-induced aging-accelerated mice. Journal of food biochemistry, 2021, Volume: 45, Issue:4 Topics: Aged; Aging; Animals; Apoptosis; Diabetes Mellitus, Experimental; Fibrosis; Humans; Inositol; Mice; Phosphatidylinositol 3-Kinases; Streptozocin	2021
Therapeutic role of d-pinitol on experimental colitis via activating Nrf2/ARE and PPAR-γ/NF-κB signaling pathways. Food & function, 2021, Mar-21, Volume: 12, Issue:6 Topics: Animals; Colitis; Dietary Supplements; Disease Models, Animal; Inositol; Male; Mice; Mice, Inbred BALB C; NF-E2-Related Factor 2; NF-kappa B; PPAR gamma; Signal Transduction	2021
Activation of PI3K/Akt Signaling Pathway in Rat Hypothalamus Induced by an Acute Oral Administration of D-Pinitol. Nutrients, 2021, Jun-30, Volume: 13, Issue:7 Topics: Administration, Oral; Animals; Blood Glucose; Enzyme Activation; Glucagon; Homeostasis; Hypothalamus; Inositol; Insulin; Insulin Resistance; Insulin-Like Growth Factor I; Male; Phosphatidylinositol 3-Kinase; Phosphorylation; Proto-Oncogene Proteins c-akt; Rats, Wistar; Signal Transduction	2021
A d-pinitol transporter, LjPLT11, regulates plant growth and nodule development in Lotus japonicus. Journal of experimental botany, 2022, 01-05, Volume: 73, Issue:1 Topics: Gene Expression Regulation, Plant; Inositol; Lotus; Nitrogen Fixation; Plant Development; Plant Proteins; Plant Roots; Root Nodules, Plant; Symbiosis	2022
Phosphoproteomics analysis of diabetic cardiomyopathy in aging-accelerated mice and effects of D-pinitol. Proteomics. Clinical applications, 2022, Volume: 16, Issue:1 Topics: Aging; Animals; Apoptosis; Diabetes Mellitus, Experimental; Diabetic Cardiomyopathies; Disease Models, Animal; Glucagon; Heart; Inositol; Insulin; Mice; Myocardium; Phosphopeptides; Phosphorylation; Protein Interaction Maps; Proteomics; Signal Transduction	2022
Hypoglycemic active principles from the leaves of Bauhinia holophylla: Comprehensive phytochemical characterization and in vivo activity profile. PloS one, 2021, Volume: 16, Issue:9 Topics: Acetonitriles; Animals; Bauhinia; Chromatography, High Pressure Liquid; Diabetes Mellitus, Experimental; Flavonoids; Glucose Tolerance Test; Glycosides; Hypoglycemic Agents; Inositol; Magnetic Resonance Spectroscopy; Male; Mice; Plant Extracts; Plant Leaves	2021
Effects of a pinitol-rich Natural product research, 2022, Volume: 36, Issue:18 Topics: Adipocytes; Animals; Glycyrrhiza; Humans; Hypertrophy; Inflammation; Inositol; Insulin; Insulin Resistance; Palmitates; Palmitic Acid; Plant Extracts; Signal Transduction	2022
Pinitol Protects Against Ox-Low-Density Lipoprotein-Induced Endothelial Inflammation and Monocytes Attachment. Journal of cardiovascular pharmacology, 2022, 03-01, Volume: 79, Issue:3 Topics: Atherosclerosis; Cell Adhesion; Endothelial Cells; Human Umbilical Vein Endothelial Cells; Humans; Inflammation; Inositol; Lipoproteins, LDL; Monocytes; Reactive Oxygen Species; Scavenger Receptors, Class E	2022
D-Pinitol Attenuated Ovalbumin-induced Allergic Rhinitis in Experimental Mice via Balancing Th1/Th2 Response. Iranian journal of allergy, asthma, and immunology, 2021, Dec-08, Volume: 20, Issue:6 Topics: Animals; Anti-Allergic Agents; Inositol; Male; Mice; Mice, Inbred BALB C; Ovalbumin; Random Allocation; Rhinitis, Allergic; Th1-Th2 Balance; Treatment Outcome	2021
d-Chiro-Inositol extends the lifespan of male Drosophila melanogaster better than d-Pinitol through insulin signaling and autophagy pathways. Experimental gerontology, 2022, Volume: 165 Topics: Animals; Antioxidants; Autophagy; Drosophila melanogaster; Inositol; Insulin; Longevity; Male; Molecular Docking Simulation	2022
d-Pinitol promotes tau dephosphorylation through a cyclin-dependent kinase 5 regulation mechanism: A new potential approach for tauopathies? British journal of pharmacology, 2022, Volume: 179, Issue:19 Topics: Animals; Cyclin-Dependent Kinase 5; Glycogen Synthase Kinase 3; Inositol; Insulins; Leptin; Mice; Phosphorylation; Rats; Rats, Wistar; Rats, Zucker; tau Proteins; Tauopathies	2022
Polyhydroxy Acids as Fabaceous Plant Components Induce Oviposition of the Common Grass Yellow Butterfly, Eurema Mandarina. Journal of chemical ecology, 2023, Volume: 49, Issue:1-2 Topics: Animals; Butterflies; Female; Inositol; Oviposition; Plant Extracts; Plants	2023
Exogenous Functional plant biology : FPB, 2023, Volume: 50, Issue:5 Topics: Inositol; Mesembryanthemum; Salt Tolerance; Salt-Tolerant Plants	2023
D-Pinitol Improved Glucose Metabolism and Inhibited Bone Loss in Mice with Diabetic Osteoporosis. Molecules (Basel, Switzerland), 2023, May-04, Volume: 28, Issue:9 Topics: Animals; Biomarkers; Diabetes Mellitus; Glucose; Inositol; Mice; Osteoporosis	2023
D-Pinitol Ameliorated Osteoporosis via Elevating D-chiro-Inositol Level in Ovariectomized Mice. Journal of nutritional science and vitaminology, 2023, Volume: 69, Issue:3 Topics: Alkaline Phosphatase; Animals; Bone Density; Female; Humans; Inositol; Mice; Mice, Inbred ICR; Osteoporosis; Osteoporosis, Postmenopausal; Ovariectomy; Tartrate-Resistant Acid Phosphatase	2023