Page last updated: 2024-08-17

methylethyl ketone and n-hexane

methylethyl ketone has been researched along with n-hexane in 34 studies

Research

Studies (34)

TimeframeStudies, this research(%)All Research%
pre-199014 (41.18)18.7374
1990's12 (35.29)18.2507
2000's5 (14.71)29.6817
2010's3 (8.82)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Blake, JF; Curatolo, WJ; Lombardo, F1
Duffy, EM; Jorgensen, WL1
Abraham, MH; Acree, WE; Ibrahim, A1
Altenkirch, H; Boegner, F; Grüning, W; Marx, P; Stoltenburg-Didinger, G; Wagner, M1
Stoltenburg-Didinger, G1
Hisanaga, N; Huang, J; Iwata, M; Ono, Y; Saito, I; Shibata, E; Takeuchi, Y1
Hisanaga, N; Huang, J; Ono, Y; Saito, I; Shibata, E; Takeuchi, Y1
Bus, JS; Robertson, P; White, EL1
Takeuchi, Y1
Lington, AW; Spencer, PS; Veronesi, B1
Fishbein, L1
Hisanaga, N; Iwata, M; Ono, Y; Takeuchi, Y2
Altenkirch, H; Schmidt, R; Schnoy, N; Wagner, HM2
Veronesi, B1
Altenkirch, H1
Aoyama, M; Hisanaga, N; Iwata, M; Kitoh, J; Ono, Y; Sugiura, Y; Takeuchi, Y1
Altenkirch, H; Spencer, PS; Stoltenburg, G; Wagner, HM1
Deliac, MM; Deliac, P; Ferrer, X; Julien, J; Lagueny, A; Vallat, JM1
Gustafsson, JA; Nilsen, OG; Toftgård, R1
Goin, CJ; Mayer, VW1
Brugnone, F; Cardona, A; Marhuenda, D; Martí, J; Perbellini, L; Roel, J1
Mulder, GJ; Opdam, JJ; Rebel-de Haan, W; van Engelen, JG1
Bucher, JR; Etheridge, AS; Mathews, JM; Raymer, JH; Velez, GR1
Mortensen, B; Nilsen, OG; Zahlsen, K1
Ichihara, G; Kamijima, M; Saito, I; Shibata, E; Takeuchi, Y; Toida, M; Yu, X1
Burgaz, S; Erdem, O; Imir, T; Karakaya, A; Karakaya, AE; Yücel, A; Yücesoy, B1
Ernstgård, L; Gullstrand, E; Johanson, G; Löf, A; Shibata, E; Sigvardsson, K1
Allshire, A; Heffron, JJ; McDermott, C; van Pelt, FN1
Allshire, A; Heffron, JJ; McDermott, C; van Pelt, F1
Elleuch, B; Gargouri, I; Khadhraoui, M; Larbi Masmoudi, M; Leroyer, A; Nisse, C; Zmirou-Navier, D1
Estevan, C; Ferri, F; Sogorb, MA; Vilanova, E1
Du, Z; Gao, B; Guo, B; Han, P; Liu, SY; Lu, GL; Ren, AL; Xing, ZX1

Reviews

3 review(s) available for methylethyl ketone and n-hexane

ArticleYear
[Visual disorders due to organic solvent poisoning].
    Sangyo igaku. Japanese journal of industrial health, 1988, Volume: 30, Issue:4

    Topics: Butanones; Carbon Disulfide; Hexanes; Humans; Methanol; Occupational Diseases; Paint; Retinal Diseases; Solvents; Toluene; Trichloroethylene; Vision Disorders

1988
Toxicity of the components of styrene polymers: polystyrene, acrylonitrile-butadiene-styrene (ABS) and styrene-butadiene-rubber (SBR). Reactants and additives.
    Progress in clinical and biological research, 1984, Volume: 141

    Topics: 1-Naphthylamine; Acrylic Resins; Acrylonitrile; Animals; Benzene; Benzene Derivatives; Butadienes; Butanones; Chemical Industry; Dibutyl Phthalate; Flame Retardants; Hexanes; Humans; Polystyrenes; Solvents

1984
[Sniffing addiction and sniffing neuropathy. Social data, practices, clinical and neurological complications as well as experimental findings in solvents abuse].
    Schriftenreihe Neurologie, 1982, Volume: 23

    Topics: Adolescent; Adult; Animals; Axons; Butanones; Female; Hexanes; Humans; Hydrocarbons; Liver; Male; Microsomes, Liver; Nerve Tissue; Nervous System Diseases; Oxygenases; Paralysis; Pregnancy; Prognosis; Psychotherapy, Group; Rats; Socioeconomic Factors; Solvents; Substance-Related Disorders

1982

Other Studies

31 other study(ies) available for methylethyl ketone and n-hexane

ArticleYear
Computation of brain-blood partitioning of organic solutes via free energy calculations.
    Journal of medicinal chemistry, 1996, Nov-22, Volume: 39, Issue:24

    Topics: Animals; Blood-Brain Barrier; Brain; Cattle; Cells, Cultured; Endothelium, Vascular; Membrane Lipids; Microcirculation; Molecular Conformation; Molecular Structure; Monte Carlo Method; Permeability; Pharmaceutical Preparations; Software; Solubility; Thermodynamics

1996
Prediction of drug solubility from Monte Carlo simulations.
    Bioorganic & medicinal chemistry letters, 2000, Jun-05, Volume: 10, Issue:11

    Topics: Monte Carlo Method; Pharmaceutical Preparations; Solubility

2000
Air to lung partition coefficients for volatile organic compounds and blood to lung partition coefficients for volatile organic compounds and drugs.
    European journal of medicinal chemistry, 2008, Volume: 43, Issue:3

    Topics: Air; Animals; Humans; Lung; Organic Chemicals; Probability; Rats; Tissue Distribution; Volatilization

2008
Specific neurotoxic effects of different organic solvents on dissociated cultures of the nervous system.
    Neurotoxicology, 1992,Spring, Volume: 13, Issue:1

    Topics: Animals; Butanones; Cells, Cultured; Chick Embryo; Hexanes; Hexanones; Nervous System; Neurites; Neurons

1992
The effect of pre- and postnatal exposure to organic solvents on the development of the cerebellar cortex in the rat.
    Progress in histochemistry and cytochemistry, 1991, Volume: 23, Issue:1-4

    Topics: Animals; Butanones; Cerebellar Cortex; Female; Hexanes; Histocytochemistry; Maternal-Fetal Exchange; NADH Tetrazolium Reductase; Pregnancy; Rats; Rats, Inbred Strains; Solvents; Succinate Dehydrogenase

1991
Changes in urinary n-hexane metabolites by co-exposure to various concentrations of methyl ethyl ketone and fixed n-hexane levels.
    Archives of toxicology, 1990, Volume: 64, Issue:2

    Topics: Administration, Inhalation; Animals; Butanones; Chromatography, Gas; Dose-Response Relationship, Drug; Drug Interactions; Hexanes; Male; Rats; Rats, Inbred Strains

1990
Effects of MEK on kinetics of n-hexane metabolites in serum.
    Archives of toxicology, 1990, Volume: 64, Issue:3

    Topics: Animals; Aorta, Abdominal; Butanones; Hexanes; Hexanones; Kinetics; Male; Rats; Rats, Inbred Strains

1990
Effects of methyl ethyl ketone pretreatment on hepatic mixed-function oxidase activity and on in vivo metabolism of n-hexane.
    Xenobiotica; the fate of foreign compounds in biological systems, 1989, Volume: 19, Issue:7

    Topics: Animals; Butanones; Cytochrome P-450 Enzyme System; Hexanes; In Vitro Techniques; Liver; Male; Mixed Function Oxygenases; Rats; Rats, Inbred F344; Subcellular Fractions; Time Factors

1989
A tissue culture model of methyl ethyl ketone's potentiation of n-hexane neurotoxicity.
    Neurotoxicology, 1984,Summer, Volume: 5, Issue:2

    Topics: Animals; Butanones; Culture Techniques; Drug Synergism; Fetus; Hexanes; Mice; Microscopy, Electron; Organ Specificity; Peripheral Nervous System Diseases; Spinal Cord; Spinal Nerves

1984
Changes of n-hexane neurotoxicity and its urinary metabolites by long-term co-exposure with MEK or toluene.
    International archives of occupational and environmental health, 1984, Volume: 54, Issue:4

    Topics: Animals; Butanones; Hexanes; Male; Neural Conduction; Peripheral Nerves; Rats; Rats, Inbred Strains; Toluene

1984
Ultrastructural alteration of intrapulmonary nerves after exposure to organic solvents. A contribution to 'sniffers disease'.
    Respiration; international review of thoracic diseases, 1984, Volume: 46, Issue:4

    Topics: Animals; Axons; Butanones; Hexanes; Lung; Male; Nerve Fibers; Nervous System; Phospholipids; Rats; Rats, Inbred Strains; Schwann Cells

1984
An ultrastructural study of methyl ethyl ketone's effect on cultured nerve tissues.
    Neurotoxicology, 1984,Winter, Volume: 5, Issue:4

    Topics: Animals; Butanones; Drug Synergism; Ganglia, Spinal; Hexanes; Mice; Microscopy, Electron; Nerve Tissue; Organ Culture Techniques; Organ Specificity; Spinal Cord

1984
Changes of n-hexane metabolites in urine of rats exposed to various concentrations of n-hexane and to its mixture with toluene or MEK.
    International archives of occupational and environmental health, 1983, Volume: 53, Issue:1

    Topics: Animals; Butanones; Furans; Hexanes; Hexanols; Hexanones; Lactones; Male; Methyl n-Butyl Ketone; Rats; Rats, Inbred Strains; Toluene

1983
An experimental study of the combined effects of n-hexane and methyl ethyl ketone.
    British journal of industrial medicine, 1983, Volume: 40, Issue:2

    Topics: Animals; Body Weight; Butanones; Dose-Response Relationship, Drug; Drug Synergism; Hexanes; Male; Motor Neurons; Neural Conduction; Peripheral Nerves; Rats; Rats, Inbred Strains

1983
Nervous system responses of rats to subchronic inhalation of N-hexane and N-hexane + methyl-ethyl-ketone mixtures.
    Journal of the neurological sciences, 1982, Volume: 57, Issue:2-3

    Topics: Animals; Axons; Butanones; Cytoskeleton; Environmental Exposure; Hexanes; Male; Medulla Oblongata; Myelin Sheath; Nervous System Diseases; Paralysis; Peripheral Nerves; Rats; Rats, Inbred Strains; Spinal Cord

1982
Ultrastructural alteration of the alveolar epithelium after exposure to organic solvents.
    Respiration; international review of thoracic diseases, 1982, Volume: 43, Issue:3

    Topics: Animals; Butanones; Drug Combinations; Epithelium; Hexanes; Male; Pulmonary Alveoli; Rats; Rats, Inbred Strains; Solvents; Time Factors

1982
[Electrophysiological study of 2 cases of polyneuritis induced by a combination of n-hexane-methylethyl ketone].
    Revue d'electroencephalographie et de neurophysiologie clinique, 1982, Volume: 12, Issue:2

    Topics: Adult; Brain Stem; Butanones; Child; Electromyography; Evoked Potentials, Auditory; Female; Hexanes; Humans; Male; Neural Conduction; Peripheral Nerves; Polyneuropathies

1982
Changes in rat liver microsomal cytochrome P-450 and enzymatic activities after the inhalation of n-hexane, xylene, methyl ethyl ketone and methylchloroform for four weeks.
    Scandinavian journal of work, environment & health, 1981, Volume: 7, Issue:1

    Topics: Androstane-3,17-diol; Androstenedione; Animals; Butanones; Cytochrome P-450 Enzyme System; Hexanes; Hydrocarbons, Chlorinated; In Vitro Techniques; Male; Microsomes, Liver; Organ Size; Rats; Rats, Inbred Strains; Solvents; Trichloroethanes; Xylenes

1981
Induction of chromosome loss in yeast by combined treatment with neurotoxic hexacarbons and monoketones.
    Mutation research, 1994, Volume: 341, Issue:2

    Topics: Acetone; Aneuploidy; Butanones; Chromosome Deletion; Drug Synergism; Hexanes; Hexanones; Methyl n-Butyl Ketone; Neurotoxins; Saccharomyces cerevisiae

1994
Biological monitoring of occupational exposure to n-hexane by measurement of urinary 2,5-hexanedione.
    International archives of occupational and environmental health, 1993, Volume: 65, Issue:1

    Topics: Adolescent; Adult; Biotransformation; Butanones; Drug Interactions; Environmental Monitoring; Female; Hexanes; Hexanones; Humans; Male; Middle Aged; Occupational Exposure; Regression Analysis; Shoes; Skin Absorption; Solvents; Toluene

1993
Effect of coexposure to methyl ethyl ketone (MEK) on n-hexane toxicokinetics in human volunteers.
    Toxicology and applied pharmacology, 1997, Volume: 144, Issue:2

    Topics: Administration, Inhalation; Adult; Biotransformation; Blood Chemical Analysis; Breath Tests; Butanones; Drug Interactions; Female; Hexanes; Humans; Male; Maximum Allowable Concentration; Models, Biological

1997
Do endogenous volatile organic chemicals measured in breath reflect and maintain CYP2E1 levels in vivo?
    Toxicology and applied pharmacology, 1997, Volume: 146, Issue:2

    Topics: Acetone; Animals; Breath Tests; Butanones; Cytochrome P-450 CYP2E1; Cytochrome P-450 CYP2E1 Inhibitors; Dichloroethylenes; Gas Chromatography-Mass Spectrometry; Hexanes; Hydrocarbons; Injections, Intraperitoneal; Ketones; Lipid Peroxidation; Male; Methylation; Microsomes, Liver; Pentanones; Rats; Rats, Inbred F344; Substrate Specificity; Volatilization

1997
Metabolic interaction of n-hexane and methyl ethyl ketone in vitro in a head space rat liver S9 vial equilibration system.
    Pharmacology & toxicology, 1998, Volume: 82, Issue:2

    Topics: Animals; Butanones; Chromatography, Gas; Drug Interactions; Enzyme Induction; Hexanes; Hexanones; In Vitro Techniques; Male; Microsomes, Liver; Rats; Rats, Sprague-Dawley

1998
Urinary 2,5-hexanedione increases with potentiation of neurotoxicity in chronic coexposure to n-hexane and methyl ethyl ketone.
    International archives of occupational and environmental health, 1998, Volume: 71, Issue:2

    Topics: Animals; Butanones; Drug Interactions; Hexanes; Hexanones; Inhalation Exposure; Male; Rats; Rats, Wistar; Solvents

1998
Effects of occupational chronic co-exposure to n-hexane, toluen, and methyl ethyl ketone on NK cell activity and some immunoregulatory cytokine levels in shoe workers.
    Human & experimental toxicology, 1999, Volume: 18, Issue:9

    Topics: Adolescent; Adult; Air Pollutants, Occupational; Butanones; Cell Line; Cytokines; Enzyme-Linked Immunosorbent Assay; Hexanes; Hippurates; Humans; Industry; Interferon-gamma; Interleukin-2; Killer Cells, Natural; Male; Middle Aged; Occupational Exposure; Shoes; Toluene

1999
Changes in n-hexane toxicokinetics in short-term single exposure due to co-exposure to methyl ethyl ketone in volunteers.
    International archives of occupational and environmental health, 2002, Volume: 75, Issue:6

    Topics: Adult; Area Under Curve; Butanones; Chromatography, Gas; Confounding Factors, Epidemiologic; Dose-Response Relationship, Drug; Drug Interactions; Environmental Monitoring; Germany; Hexanes; Humans; Inhalation Exposure; Male; Middle Aged; Occupational Exposure

2002
Sub-chronic toxicity of low concentrations of industrial volatile organic pollutants in vitro.
    Toxicology and applied pharmacology, 2007, Feb-15, Volume: 219, Issue:1

    Topics: Butanones; Calcium; Cell Line, Tumor; Chromatography, Gas; Environmental Pollutants; Glutathione; Hexanes; Homeostasis; Humans; Industry; Jurkat Cells; L-Lactate Dehydrogenase; Mitogen-Activated Protein Kinases; No-Observed-Adverse-Effect Level; Organic Chemicals; Oxidation-Reduction; Phosphorylation; Signal Transduction; Solvents; Toluene

2007
In vitro exposure of jurkat T-cells to industrially important organic solvents in binary combination: interaction analysis.
    Toxicological sciences : an official journal of the Society of Toxicology, 2008, Volume: 101, Issue:2

    Topics: Butanones; Cell Membrane; Dose-Response Relationship, Drug; Drug Interactions; Glutathione; Hexanes; Humans; Industrial Waste; Jurkat Cells; Oxidation-Reduction; Solvents; T-Lymphocytes; Toluene

2008
Occupational assessment of exposure to organic solvents in an adhesive producing company in Sfax, Tunisia.
    Journal of occupational and environmental hygiene, 2012, Volume: 9, Issue:4

    Topics: Acetone; Adhesives; Air Pollutants, Occupational; Butanones; Cyclohexanes; Female; Hexanes; Humans; Male; Occupational Exposure; Solvents; Threshold Limit Values; Toluene; Trichloroethylene; Tunisia

2012
Characterization and evolution of exposure to volatile organic compounds in the Spanish shoemaking industry over a 5-year period.
    Journal of occupational and environmental hygiene, 2012, Volume: 9, Issue:11

    Topics: Acetone; Benzene; Butanones; Cyclohexanes; Hexanes; Humans; Inhalation Exposure; Maximum Allowable Concentration; Occupational Exposure; Shoes; Spain; Toluene; Ventilation; Volatile Organic Compounds

2012
[Pollution characteristics of volatile organic compounds from wastewater treatment system of vitamin C production].
    Huan jing ke xue= Huanjing kexue, 2013, Volume: 34, Issue:12

    Topics: Air Pollutants; Ascorbic Acid; Butadienes; Butanones; China; Drug Industry; Environmental Monitoring; Gas Chromatography-Mass Spectrometry; Hexanes; Hydrocarbons, Aromatic; Volatile Organic Compounds; Waste Disposal, Fluid; Wastewater

2013