Page last updated: 2024-08-17

methylene chloride and lactic acid

methylene chloride has been researched along with lactic acid in 63 studies

Research

Studies (63)

Timeframe	Studies, this research(%)	All Research%
pre-1990	1 (1.59)	18.7374
1990's	6 (9.52)	18.2507
2000's	40 (63.49)	29.6817
2010's	16 (25.40)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Hyon, SH; Ikada, Y; Wada, R	1
Benoit, JP; Cavalier, M; Thies, C	1
Adachi, N; Akaike, T; Ishihara, T; Maruyama, A	1
Chern, RT; Sah, H; Smith, MS	1
Johnston, KP; Mishima, K; Tanaka, H; Young, TJ	1
Bonneaux, F; Dellacherie, E; Gref, R; Vigneron, C; Zambaux, MF	1
Kim, HK; Park, TG	1
Sah, H	1
Birnbaum, DT; Brannon-Peppas, L; Henthorn, DB; Kosmala, JD	1
Akgerman, A; Amirpour, ML; Hile, DD; Pishko, MV	1
Crommelin, DJ; Hennink, WE; Hoechstetter, J; van de Weert, M	1
Al-Maaieh, A; Flanagan, DR	1
Wang, CH; Wang, FJ	1
Domb, AJ; Slager, J	1
Feng, Z; Ruhua, Z; Weisan, P; Xinteng, Z	1
Fujiie, S; Kaetsu, I; Kakinoki, S; Kato, M; Kuroda, D; Nakayama, M; Ohyanagi, H; Uchida, K; Yasuda, C; Yukutake, K	1
Hata, K; Kasuga, T; Kato, K; Maeda, H; Nogami, M; Ueda, M	1
Barnard, DR; Bernier, UR; Booth, MM; Kline, DL; Posey, KH; Yost, RA	1
Kim, SW; Kwon, YM	1
Chen, HL; Liang, WQ; Yu, HY; Zheng, CH	1
Chen, S; Godbee, J; Mathiowitz, E; Pattamunuch, P; Scott, E	1
Rosca, ID; Uo, M; Watari, F	1
Chen, JL; Chiang, CH; Yeh, MK	1
Evangelista, RC; Mainardes, RM	1
Allémann, E; Bilati, U; Doelker, E	1
Ameenuddin, S; Currier, BL; Friedman, JA; Knight, AM; Krych, AJ; Lewellyn, EB; Lu, L; Mantila, SM; Marsh, RW; Moore, MJ; Spinner, RJ; Windebank, AJ; Yaszemski, MJ	1
He, JT; Li, GP; Mo, W; Song, HY; Su, HB; Tao, XM	1
Mohamed, F; van der Walle, CF	1
Castellanos, IJ; Flores, G; Griebenow, K	1
Bilibin, AIu; Blinova, MI; Kukhareva, LV; Pinaev, GP; Shved, IuA; Solov'ev, AIu; Zorin, IM	1
Huang, SS; Liu, R; Ma, GH; Su, ZG; Wan, YH	1
Freeman, T; Graves, RA; Mandal, TK; Moiseyev, R; Pamajula, S; Praetorius, N	1
Khan, M; Mustafa, F; Siddiqui, A; Zaghloul, AA	1
Donnelly, RF; Marouf, W; McCarron, PA	1
Blasi, P; Giovagnoli, S; Ricci, M; Rossi, C; Schoubben, A	1
Berkland, C; Kim, KK; Pack, DW; Pollauf, E; Varde, N	1
Babak, VG; Baros, F; Boulanouar, O; Boury, F; Fromm, M; Kildeeva, NR; Maincent, P; Ubrich, N	1
Menaszek, E; Pamula, E	1
Cai, Z; Chen, Q; He, J; Hou, S; Li, Y; Song, X; Xu, F; Zhao, R; Zhao, Y	1
Bae, YH; Taluja, A	1
Chang, JK; Chen, HT; Fu, YC; Ho, ML; Tsai, TH; Wang, CK; Wang, GJ	1
Mok, H; Park, TG	1
Lee, MC; Lee, SH; Lee, SJ; Lee, SY; Park, KD; Shim, IK; Yook, YJ	1
Kasuga, T; Obata, A; Tokuda, S	1
Guo, M; Jin, T; Wu, F; Yuan, W	1
Benoît, JP; Boury, F; Malzert-Fréon, A; Schönhammer, K	1
Argemí, A; Saurina, J; Subra-Paternault, P; Vega, A	1
Burgess, DJ; Rawat, A	1
Negulescu, II; Stefanescu, C; Stefanescu, EA	1
About, I; Boyron, O; Deloge, A; Fessi, H; Kalaji, N; Sheibat-Othman, N	1
Coleman, J; Lowman, A	1
Cornejo, JJ; Daiguji, H; Takemura, F	1
Cardona, CA; Gonzalez, R; Posada, JA	1
Gong, H; Li, X; Tang, Y; Wang, Y; Wei, Y; Zhang, J; Zhou, J	1
Demas, JN; Evans, RE; Fraser, CL; Liu, T; Trindle, CO; Xu, S; Zhang, G	1
Shen, XC; Tao, L; Xiao, CD	1
Dvořáčkov, K; Kejdušová, M; Vetchý, D; Vysloužil, J	1
Das, DB; Ekanem, EE; Shahmohamadi, H; Sharma, L; Tauanov, Z; Vladisavljević, GT	1
Beneš, L; Doležel, P; Dvořáčková, K; Kejdušová, M; Košťál, V; Vysloužil, J	1
Doležel, P; Dvořáčková, K; Kejdušová, M; Košťál, V; Lukáč, R; Mašek, J; Mašková, E; Vetchý, D; Vysloužil, J	1
Felice, B; Prabhakaran, MP; Ramakrishna, S; Zamani, M	1
Chitrattha, S; Phaechamud, T	1
Amel Jamehdar, S; Amini, Y; Musavi, D; Sadri, K; Tafaghodi, M; Zare, S	1

Other Studies

63 other study(ies) available for methylene chloride and lactic acid

Article	Year
Lactic acid oligomer microspheres containing hydrophilic drugs. Journal of pharmaceutical sciences, 1990, Volume: 79, Issue:10 Topics: Aclarubicin; Animals; Antineoplastic Agents; Chemical Phenomena; Chemistry, Physical; Chromatography, Gel; Female; Insulin; Lactates; Lactic Acid; Methylene Chloride; Microscopy, Electron, Scanning; Microspheres; Molecular Weight; Pharmaceutical Preparations; Rats; Rats, Inbred Strains; Water	1990
The formation and characterization of hydrocortisone-loaded poly((+/-)-lactide) microspheres. The Journal of pharmacy and pharmacology, 1986, Volume: 38, Issue:4 Topics: Calorimetry, Differential Scanning; Drug Compounding; Drug Stability; Emulsions; Hydrocortisone; Lactic Acid; Methylcellulose; Methylene Chloride; Microspheres; Polyesters; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Polyvinyl Alcohol; X-Ray Diffraction	1986
Preparation of nanoparticles bearing high density carbohydrate chains using carbohydrate-carrying polymers as emulsifier. Biomaterials, 1994, Volume: 15, Issue:13 Topics: Animals; Binding, Competitive; Carbohydrate Metabolism; Carbohydrates; Centrifugation; Coleoptera; Emulsions; Excipients; Female; Flow Cytometry; In Vitro Techniques; Lactates; Lactic Acid; Lactose; Lectins; Liver; Methylene Chloride; Microscopy, Electron, Scanning; Particle Size; Polyesters; Polymers; Polystyrenes; Rats; Rats, Sprague-Dawley; Spectrometry, Fluorescence	1994
A novel method of preparing PLGA microcapsules utilizing methylethyl ketone. Pharmaceutical research, 1996, Volume: 13, Issue:3 Topics: Butanones; Chemistry, Pharmaceutical; Drug Compounding; Lactic Acid; Methylene Chloride; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Solvents	1996
Encapsulation of lysozyme in a biodegradable polymer by precipitation with a vapor-over-liquid antisolvent. Journal of pharmaceutical sciences, 1999, Volume: 88, Issue:6 Topics: Animals; Biocompatible Materials; Biodegradation, Environmental; Carbon Dioxide; Chemical Precipitation; Chemistry, Pharmaceutical; Chickens; Delayed-Action Preparations; Drug Compounding; Egg Proteins; Gases; Lactic Acid; Methylene Chloride; Microscopy, Electron, Scanning; Microspheres; Muramidase; Particle Size; Polyesters; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Solubility; Solvents	1999
Preparation and characterization of protein C-loaded PLA nanoparticles. Journal of controlled release : official journal of the Controlled Release Society, 1999, Aug-05, Volume: 60, Issue:2-3 Topics: Anticoagulants; Delayed-Action Preparations; Drug Stability; Humans; In Vitro Techniques; Lactic Acid; Methylene Chloride; Microspheres; Particle Size; Polymers; Polyvinyl Alcohol; Protein C; Sonication; Surface-Active Agents	1999
Microencapsulation of human growth hormone within biodegradable polyester microspheres: protein aggregation stability and incomplete release mechanism. Biotechnology and bioengineering, 1999, Dec-20, Volume: 65, Issue:6 Topics: Acetates; Adsorption; Biocompatible Materials; Chromatography, High Pressure Liquid; Circular Dichroism; Delayed-Action Preparations; Dimerization; Drug Carriers; Drug Compounding; Freeze Drying; Guanidine; Human Growth Hormone; Humans; Lactic Acid; Methylene Chloride; Microspheres; Polyesters; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Protein Structure, Secondary; Sodium Dodecyl Sulfate; Solubility	1999
Ethyl formate - alternative dispersed solvent useful in preparing PLGA microspheres. International journal of pharmaceutics, 2000, Feb-15, Volume: 195, Issue:1-2 Topics: Chemistry, Pharmaceutical; Drug Carriers; Drug Compounding; Emulsions; Lactic Acid; Methylene Chloride; Microscopy, Electron, Scanning; Microspheres; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Progesterone; Propionates; Solvents	2000
Controlled release of beta-estradiol from PLAGA microparticles: the effect of organic phase solvent on encapsulation and release. Journal of controlled release : official journal of the Controlled Release Society, 2000, Apr-03, Volume: 65, Issue:3 Topics: Acetates; Drug Carriers; Drug Compounding; Emulsions; Estradiol; Lactic Acid; Methanol; Methylene Chloride; Microspheres; Oils; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Solvents	2000
Active growth factor delivery from poly(D,L-lactide-co-glycolide) foams prepared in supercritical CO(2). Journal of controlled release : official journal of the Controlled Release Society, 2000, May-15, Volume: 66, Issue:2-3 Topics: Animals; Biocompatible Materials; Carbon Dioxide; Cattle; Cold Temperature; Drug Carriers; Drug Delivery Systems; Fibroblast Growth Factor 2; Growth Substances; Lactic Acid; Methylene Chloride; Microscopy, Electron, Scanning; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Solutions	2000
The effect of a water/organic solvent interface on the structural stability of lysozyme. Journal of controlled release : official journal of the Controlled Release Society, 2000, Sep-03, Volume: 68, Issue:3 Topics: Anti-Infective Agents; Drug Carriers; Electrophoresis, Polyacrylamide Gel; Emulsions; Lactic Acid; Methylene Chloride; Microspheres; Muramidase; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Protein Denaturation; Solvents; Spectrophotometry, Ultraviolet; Spectroscopy, Fourier Transform Infrared; Water	2000
Salt and cosolvent effects on ionic drug loading into microspheres using an O/W method. Journal of controlled release : official journal of the Controlled Release Society, 2001, Jan-29, Volume: 70, Issue:1-2 Topics: Ethanol; Lactic Acid; Methylene Chloride; Microspheres; Polyesters; Polymers; Quinidine; Solubility; Thermodynamics	2001
Sustained release of etanidazole from spray dried microspheres prepared by non-halogenated solvents. Journal of controlled release : official journal of the Controlled Release Society, 2002, Jun-17, Volume: 81, Issue:3 Topics: Acetates; Biocompatible Materials; Delayed-Action Preparations; Drug Carriers; Etanidazole; Ethanol; Lactic Acid; Methylene Chloride; Microspheres; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Radiation-Sensitizing Agents; Solubility; Solvents; Surface Properties; Time Factors; Viscosity	2002
Stereocomplexes based on poly(lactic acid) and insulin: formulation and release studies. Biomaterials, 2002, Volume: 23, Issue:22 Topics: Acetonitriles; Biocompatible Materials; Calorimetry, Differential Scanning; Ethanol; Freezing; Hexanes; Hydrogen-Ion Concentration; Insulin; Lactic Acid; Methylene Chloride; Microscopy, Electron, Scanning; Peptides; Polyesters; Polymers; Solvents; Stereoisomerism; Temperature; Time Factors; Water	2002
Preparation and evaluation of poly (D, L-lactic acid) (PLA) or D, L-lactide/glycolide copolymer (PLGA) microspheres with estradiol. Die Pharmazie, 2002, Volume: 57, Issue:10 Topics: Drug Compounding; Estradiol; Excipients; Lactic Acid; Methylene Chloride; Microscopy, Electron, Scanning; Microspheres; Molecular Weight; Particle Size; Polyesters; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Solubility	2002
Preparation of poly-lactic acid microspheres containing the angiogenesis inhibitor TNP-470 with medium-chain triglyceride and the in vitro evaluation of release profiles. European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 2003, Volume: 55, Issue:2 Topics: Angiogenesis Inhibitors; Chemistry, Pharmaceutical; Cyclohexanes; Delayed-Action Preparations; Drug Carriers; Drug Compounding; Drug Stability; Half-Life; Lactic Acid; Methylene Chloride; Microscopy, Electron, Scanning; Microspheres; O-(Chloroacetylcarbamoyl)fumagillol; Particle Size; Polyesters; Polymers; Sesquiterpenes; Time Factors; Triglycerides	2003
Preparation of poly(lactic acid) composites containing calcium carbonate (vaterite). Biomaterials, 2003, Volume: 24, Issue:19 Topics: Apatites; Biocompatible Materials; Bone Substitutes; Calcium Carbonate; Lactic Acid; Magnetic Resonance Spectroscopy; Materials Testing; Methylene Chloride; Microscopy, Electron, Scanning; Polyesters; Polymers	2003
Synergistic attraction of Aedes aegypti (L.) to binary blends of L-lactic acid and acetone, dichloromethane, or dimethyl disulfide. Journal of medical entomology, 2003, Volume: 40, Issue:5 Topics: Acetone; Aedes; Animals; Disulfides; Drug Interactions; Feeding Behavior; Lactic Acid; Methylene Chloride; Odorants	2003
Biodegradable triblock copolymer microspheres based on thermosensitive sol-gel transition. Pharmaceutical research, 2004, Volume: 21, Issue:2 Topics: Animals; Biodegradation, Environmental; Diabetes Mellitus, Experimental; Emulsions; Hypoglycemic Agents; In Vitro Techniques; Insulin; Lactic Acid; Male; Methylene Chloride; Microscopy, Electron, Scanning; Microspheres; Particle Size; Phase Transition; Polyethylene Glycols; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Rats; Rats, Sprague-Dawley; Temperature; Water	2004
Evaluation of different methods to determine the loading of proteins in PLGA microspheres. Die Pharmazie, 2004, Volume: 59, Issue:3 Topics: Acetonitriles; Drug Compounding; Lactic Acid; Methylene Chloride; Microspheres; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Proteins; Serum Albumin, Bovine; Solubility; Solvents	2004
Role of solvent/non-solvent ratio on microsphere formation using the solvent removal method. Journal of microencapsulation, 2004, Volume: 21, Issue:2 Topics: Acetates; Biocompatible Materials; Chemical Precipitation; Delayed-Action Preparations; Diffusion; Drug Compounding; Fluorescein-5-isothiocyanate; Lactic Acid; Methylene Chloride; Microscopy, Electron, Scanning; Microspheres; Polyesters; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Serum Albumin, Bovine; Solvents; Surface Properties; Viscosity	2004
Microparticle formation and its mechanism in single and double emulsion solvent evaporation. Journal of controlled release : official journal of the Controlled Release Society, 2004, Sep-30, Volume: 99, Issue:2 Topics: Capsules; Chemistry, Pharmaceutical; Drug Carriers; Drug Delivery Systems; Emulsions; Glycolates; Lactic Acid; Lasers; Methylene Chloride; Microscopy; Microspheres; Nanostructures; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Porosity; Solvents; Volatilization	2004
The mechanism of surface-indented protein-loaded PLGA microparticle formation: the effects of salt (NaCl) on the solidification process. Journal of microencapsulation, 2004, Volume: 21, Issue:8 Topics: Adsorption; Drug Compounding; Drug Delivery Systems; Hydrogen-Ion Concentration; Lactic Acid; Methylene Chloride; Microspheres; Osmotic Pressure; Ovalbumin; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Serum Albumin, Bovine; Sodium Chloride; Surface Properties	2004
Praziquantel-loaded PLGA nanoparticles: preparation and characterization. Journal of microencapsulation, 2005, Volume: 22, Issue:1 Topics: Acetates; Biocompatible Materials; Calorimetry, Differential Scanning; Delayed-Action Preparations; Drug Compounding; Lactic Acid; Methylene Chloride; Microscopy, Electron, Scanning; Nanostructures; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Praziquantel; Solvents; Spectroscopy, Fourier Transform Infrared	2005
Poly(D,L-lactide-co-glycolide) protein-loaded nanoparticles prepared by the double emulsion method--processing and formulation issues for enhanced entrapment efficiency. Journal of microencapsulation, 2005, Volume: 22, Issue:2 Topics: Animals; Biocompatible Materials; Cattle; Delayed-Action Preparations; Drug Compounding; Emulsifying Agents; Lactic Acid; Methylene Chloride; Molecular Weight; Nanostructures; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Serum Albumin, Bovine; Solvents; Sonication; Time Factors	2005
Multiple-channel scaffolds to promote spinal cord axon regeneration. Biomaterials, 2006, Volume: 27, Issue:3 Topics: Absorbable Implants; Animals; Animals, Genetically Modified; Axons; Delayed-Action Preparations; Dextrans; Female; Fluorescein-5-isothiocyanate; Green Fluorescent Proteins; Guided Tissue Regeneration; Implants, Experimental; Lactic Acid; Male; Methylene Chloride; Nerve Regeneration; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Porosity; Rats; Rats, Sprague-Dawley; Schwann Cells; Spinal Cord; Spinal Cord Injuries; Tissue Engineering; Tomography, X-Ray Computed	2006
Stabilization and encapsulation of a staphylokinase variant (K35R) into poly(lactic-co-glycolic acid) microspheres. International journal of pharmaceutics, 2006, Feb-17, Volume: 309, Issue:1-2 Topics: Chemistry, Pharmaceutical; Delayed-Action Preparations; Drug Carriers; Enzyme Stability; Excipients; Lactic Acid; Metalloendopeptidases; Methylene Chloride; Microspheres; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Polyvinyl Alcohol; Protein Denaturation; Solubility; Solvents; Surface Properties; Technology, Pharmaceutical; Time Factors; Ultrasonics	2006
PLGA microcapsules with novel dimpled surfaces for pulmonary delivery of DNA. International journal of pharmaceutics, 2006, Mar-27, Volume: 311, Issue:1-2 Topics: Aerosols; Capsules; DNA; Emulsions; Gene Transfer Techniques; Glycolates; Hexoses; Lactic Acid; Methylene Chloride; Microspheres; Molecular Weight; Poloxamer; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Polysorbates; Porosity; Respiratory System; Solubility; Solvents; Surface Properties; Surface-Active Agents; Technology, Pharmaceutical; Thermodynamics; Time Factors; Transition Temperature; Water	2006
Effect of cyclodextrins on alpha-chymotrypsin stability and loading in PLGA microspheres upon S/O/W encapsulation. Journal of pharmaceutical sciences, 2006, Volume: 95, Issue:4 Topics: 2-Hydroxypropyl-beta-cyclodextrin; beta-Cyclodextrins; Chymotrypsin; Drug Compounding; Emulsions; Enzyme Stability; Excipients; Lactic Acid; Methylene Chloride; Microspheres; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Solvents; Surface Properties; Water	2006
[Elaboration of biodegradable polymer substrate for cultivation of human dermal fibroblasts]. Tsitologiia, 2006, Volume: 48, Issue:2 Topics: Acetone; Biocompatible Materials; Cell Adhesion; Cells, Cultured; Fibroblasts; Humans; Hydrophobic and Hydrophilic Interactions; Lactic Acid; Materials Testing; Methylene Chloride; Polyesters; Polymers; Skin; Solvents	2006
Preparation of insulin-loaded PLA/PLGA microcapsules by a novel membrane emulsification method and its release in vitro. Colloids and surfaces. B, Biointerfaces, 2006, Aug-01, Volume: 51, Issue:1 Topics: Capsules; Emulsions; Humans; Hydrogen-Ion Concentration; In Vitro Techniques; Insulin; Insulin Secretion; Lactic Acid; Membranes, Artificial; Methylene Chloride; Microscopy, Electron, Scanning; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Recombinant Proteins; Solvents; Technology, Pharmaceutical; Time Factors; Volatilization; Water	2006
Effect of co-solvents on the characteristics of enkephalin microcapsules. Journal of biomaterials science. Polymer edition, 2006, Volume: 17, Issue:6 Topics: Biocompatible Materials; Biodegradation, Environmental; Capsules; Drug Compounding; Enkephalin, Leucine; Lactic Acid; Materials Testing; Methylene Chloride; Microscopy, Electron, Scanning; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Solvents; Surface Properties; Thermodynamics	2006
Response surface methodology to obtain beta-estradiol biodegradable microspheres for long-term therapy of osteoporosis. Pharmaceutical development and technology, 2006, Volume: 11, Issue:3 Topics: Biodegradation, Environmental; Chemistry, Pharmaceutical; Drug Carriers; Drug Compounding; Emulsions; Estradiol; Lactic Acid; Methanol; Methylene Chloride; Microscopy, Electron, Scanning; Microspheres; Oils; Osteoporosis; Particle Size; Polyesters; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Solvents; Spectroscopy, Fourier Transform Infrared; Time Factors; Water; X-Ray Diffraction	2006
Celecoxib-loaded poly(D,L-lactide-co-glycolide) nanoparticles prepared using a novel and controllable combination of diffusion and emulsification steps as part of the salting-out procedure. Journal of microencapsulation, 2006, Volume: 23, Issue:5 Topics: Acetone; Biocompatible Materials; Calorimetry, Differential Scanning; Celecoxib; Cyclooxygenase Inhibitors; Delayed-Action Preparations; Diffusion; Drug Compounding; Lactic Acid; Magnesium Chloride; Methylene Chloride; Microscopy, Electron, Scanning; Nanoparticles; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Pyrazoles; Solvents; Sonication; Sulfonamides; Surface Properties; Viscosity	2006
Preparation of large porous biodegradable microspheres by using a simple double-emulsion method for capreomycin sulfate pulmonary delivery. International journal of pharmaceutics, 2007, Mar-21, Volume: 333, Issue:1-2 Topics: Acetone; Administration, Inhalation; Antibiotics, Antitubercular; Capreomycin; Chemistry, Pharmaceutical; Drug Carriers; Drug Compounding; Emulsifying Agents; Emulsions; Hypromellose Derivatives; Lactic Acid; Methylcellulose; Methylene Chloride; Microscopy, Electron, Scanning; Microspheres; Models, Chemical; Models, Statistical; Oils; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Porosity; Predictive Value of Tests; Reproducibility of Results; Spectrophotometry, Ultraviolet; Surface Properties; Technology, Pharmaceutical; Water	2007
Monodisperse liquid-filled biodegradable microcapsules. Pharmaceutical research, 2007, Volume: 24, Issue:5 Topics: Algorithms; Biocompatible Materials; Capsules; Dextrans; Drug Compounding; Emulsifying Agents; Fatty Acids, Monounsaturated; Fluorescent Dyes; Hexanes; Lactic Acid; Methylene Chloride; Microscopy, Electron, Scanning; Oxazines; Particle Size; Polyanhydrides; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Pulsatile Flow; Rapeseed Oil; Rhodamines; Serum Albumin, Bovine; Silicone Oils; Solubility; Solutions; Water	2007
Impact of bulk and surface properties of some biocompatible hydrophobic polymers on the stability of methylene chloride-in-water mini-emulsions used to prepare nanoparticles by emulsification-solvent evaporation. Colloids and surfaces. B, Biointerfaces, 2007, Oct-01, Volume: 59, Issue:2 Topics: Acrylic Resins; Biocompatible Materials; Emulsions; Hydrophobic and Hydrophilic Interactions; Lactic Acid; Methylene Chloride; Nanoparticles; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Solutions; Solvents; Static Electricity; Surface Properties; Water	2007
In vitro and in vivo degradation of poly(L: -lactide-co-glycolide) films and scaffolds. Journal of materials science. Materials in medicine, 2008, Volume: 19, Issue:5 Topics: Absorbable Implants; Animals; Biocompatible Materials; Catalysis; Inflammation; Lactic Acid; Materials Testing; Methylene Chloride; Microscopy, Atomic Force; Microscopy, Electron, Scanning; Molecular Weight; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Porosity; Surface Properties; Time Factors; Tissue Engineering	2008
Dual agents loaded PLGA nanoparticles: systematic study of particle size and drug entrapment efficiency. European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 2008, Volume: 69, Issue:2 Topics: Acetone; Antineoplastic Agents, Phytogenic; Calorimetry, Differential Scanning; Chemical Phenomena; Chemistry, Pharmaceutical; Chemistry, Physical; Electrochemistry; Hydrogen-Ion Concentration; Lactic Acid; Methylene Chloride; Microscopy, Electron, Transmission; Nanoparticles; Particle Size; Pharmaceutical Preparations; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Quercetin; Vincristine	2008
Role of a novel multifunctional excipient poly(ethylene glycol)-block-oligo(vinyl sulfadimethoxine) in controlled release of lysozyme from PLGA microspheres. International journal of pharmaceutics, 2008, Jun-24, Volume: 358, Issue:1-2 Topics: Anti-Bacterial Agents; Chemistry, Pharmaceutical; Drug Compounding; Drug Stability; Emulsions; Excipients; Lactic Acid; Methylene Chloride; Microscopy, Electron, Scanning; Microspheres; Muramidase; Nanoparticles; Polyethylene Glycols; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Protein Binding; Sulfadimethoxine; Surface-Active Agents	2008
Controlled release carrier of BSA made by W/O/W emulsion method containing PLGA and hydroxyapatite. Journal of controlled release : official journal of the Controlled Release Society, 2008, Jun-04, Volume: 128, Issue:2 Topics: Adsorption; Animals; BALB 3T3 Cells; Biological Availability; Buffers; Cell Survival; Drug Carriers; Durapatite; Electron Probe Microanalysis; Emulsions; Fluorescein-5-isothiocyanate; Glycolates; Hot Temperature; Hydrogen-Ion Concentration; Lactic Acid; Methylene Chloride; Mice; Microscopy, Electron, Scanning; Microscopy, Fluorescence; Microspheres; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polyvinyl Alcohol; Serum Albumin; Serum Albumin, Bovine; Surface Properties; Water; X-Ray Diffraction	2008
Water-free microencapsulation of proteins within PLGA microparticles by spray drying using PEG-assisted protein solubilization technique in organic solvent. European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 2008, Volume: 70, Issue:1 Topics: Animals; Cattle; Chemistry, Pharmaceutical; Delayed-Action Preparations; Desiccation; Drug Carriers; Drug Compounding; Human Growth Hormone; Humans; Kinetics; Lactic Acid; Methylene Chloride; Particle Size; Polyethylene Glycols; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Proteins; Recombinant Proteins; Serum Albumin, Bovine; Solubility; Solvents; Surface Properties; Technology, Pharmaceutical; Water	2008
Healing of articular cartilage defects treated with a novel drug-releasing rod-type implant after microfracture surgery. Journal of controlled release : official journal of the Controlled Release Society, 2008, Aug-07, Volume: 129, Issue:3 Topics: Animals; Arthroplasty, Subchondral; Buffers; Calcium Phosphates; Cartilage, Articular; Chloroform; Coloring Agents; Compressive Strength; Dehydroepiandrosterone Sulfate; Drug Implants; Hydrogen-Ion Concentration; Lactic Acid; Methylene Chloride; Molecular Weight; Phenazines; Phosphates; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Powders; Prostheses and Implants; Rabbits; Solvents; Temperature; Time Factors; Viscosity; Wound Healing	2008
Enhanced in vitro cell activity on silicon-doped vaterite/poly(lactic acid) composites. Acta biomaterialia, 2009, Volume: 5, Issue:1 Topics: 3T3 Cells; Animals; Biocompatible Materials; Calcium Carbonate; Cell Differentiation; Cell Proliferation; In Vitro Techniques; Lactic Acid; Methylene Chloride; Mice; Microscopy, Electron, Scanning; Models, Biological; Molecular Weight; Osteoblasts; Polyesters; Polymers; Propylamines; Silanes; Silicon	2009
Development of protein delivery microsphere system by a novel S/O/O/W multi-emulsion. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2009, Feb-15, Volume: 36, Issue:2-3 Topics: Animals; Biological Availability; Cattle; Chromatography, Gel; Delayed-Action Preparations; Dextrans; Drug Delivery Systems; Emulsions; Glycerol; Horses; Lactic Acid; Methylene Chloride; Microscopy, Electron, Scanning; Microspheres; Myoglobin; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polyvinyl Alcohol; Propylene Glycol; Proteins; Serum Albumin, Bovine; Surface Properties	2009
Interactions between poly(ethylene glycol) and protein in dichloromethane/water emulsions. 2. Conditions required to obtain spontaneous emulsification allowing the formation of bioresorbable poly(D,L lactic acid) microparticles. European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 2009, Volume: 73, Issue:1 Topics: Adsorption; Animals; Capsules; Cattle; Emulsions; Humans; Lactic Acid; Methylene Chloride; Polyesters; Polyethylene Glycols; Polymers; Protein Binding; Serum Albumin; Water	2009
Characterization of azacytidine/poly(L-lactic) acid particles prepared by supercritical antisolvent precipitation. Journal of pharmaceutical and biomedical analysis, 2009, Dec-05, Volume: 50, Issue:5 Topics: Azacitidine; Carbon Dioxide; Chemistry, Pharmaceutical; Chromatography; Dimethyl Sulfoxide; Drug Delivery Systems; Equipment Design; Hydrogen-Ion Concentration; Kinetics; Lactic Acid; Methylene Chloride; Particle Size; Polyesters; Polymers; Pressure; Solvents; Temperature	2009
Effect of ethanol as a processing co-solvent on the PLGA microsphere characteristics. International journal of pharmaceutics, 2010, Jul-15, Volume: 394, Issue:1-2 Topics: Crystallization; Dexamethasone; Drug Carriers; Ethanol; Lactic Acid; Methylene Chloride; Microspheres; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Solubility; Solvents; Viscosity	2010
Biodegradable polymeric capsules obtained via room temperature spray drying: preparation and characterization. Journal of biomaterials applications, 2011, Volume: 25, Issue:8 Topics: Absorbable Implants; Biocompatible Materials; Calorimetry, Differential Scanning; Capsules; Desiccation; Drug Carriers; Hydroxybutyrates; Lactic Acid; Methylene Chloride; Microscopy, Electron, Scanning; Nanocapsules; Polyesters; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Rheology; Solutions; Temperature; Thermogravimetry; Transition Temperature; Viscosity; Vitrification	2011
Controlled release carriers of growth factors FGF-2 and TGFbeta1: synthesis, characterization and kinetic modelling. Journal of biomedical nanotechnology, 2010, Volume: 6, Issue:2 Topics: Drug Delivery Systems; Fibroblast Growth Factor 2; Fluorescein-5-isothiocyanate; Humans; Lactic Acid; Methylene Chloride; Microscopy, Confocal; Microscopy, Electron, Scanning; Microspheres; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Protein Stability; Serum Albumin, Bovine; Surface Properties; Transforming Growth Factor beta1	2010
Biodegradable nanoparticles for protein delivery: analysis of preparation conditions on particle morphology and protein loading, activity and sustained release properties. Journal of biomaterials science. Polymer edition, 2012, Volume: 23, Issue:9 Topics: Acetates; Acetone; Animals; Cattle; Delayed-Action Preparations; Lactic Acid; Methylene Chloride; Muramidase; Nanoparticles; Nerve Regeneration; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Protein Denaturation; Serum Albumin, Bovine; Solubility; Solvents; Spinal Cord Injuries; Sucrose	2012
Factors affecting the size and uniformity of hollow poly(lactic acid) microcapsules fabricated from microbubble templates. The journal of physical chemistry. B, 2011, Dec-01, Volume: 115, Issue:47 Topics: Capsules; Lactic Acid; Methylene Chloride; Microbubbles; Polyesters; Polymers; Polyvinyl Alcohol; Water	2011
Analysis of the production process of optically pure D-lactic acid from raw glycerol using engineered Escherichia coli strains. Applied biochemistry and biotechnology, 2012, Volume: 166, Issue:3 Topics: Acetyltransferases; Amines; Computer Simulation; Costs and Cost Analysis; Escherichia coli; Escherichia coli Proteins; Fermentation; Genetic Engineering; Glycerol; Industrial Microbiology; L-Lactate Dehydrogenase; Lactic Acid; Methylene Chloride; Mutation; Phosphate Acetyltransferase; Research Design; Stereoisomerism; Succinate Dehydrogenase	2012
Nanocomplexation-assisted solubilization of pDNA in organic solvents for improved microencapsulation. Journal of colloid and interface science, 2013, Mar-15, Volume: 394 Topics: DNA; Drug Compounding; Lactic Acid; Methylene Chloride; Models, Molecular; Plasmids; Polyethylene Glycols; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polylysine; Solubility; Solvents	2013
Aromatic difluoroboron β-diketonate complexes: effects of π-conjugation and media on optical properties. Inorganic chemistry, 2013, Apr-01, Volume: 52, Issue:7 Topics: Boron Compounds; Electrons; Fluorescent Dyes; Keto Acids; Lactic Acid; Light; Methylene Chloride; Polyesters; Polymers; Quantum Theory; Spectrometry, Fluorescence; Structure-Activity Relationship	2013
Modified emulsion solvent evaporation method for fabricating core-shell microspheres. International journal of pharmaceutics, 2013, Aug-16, Volume: 452, Issue:1-2 Topics: Acetates; Aspirin; Delayed-Action Preparations; Drug Compounding; Drug Delivery Systems; Emulsions; Lactic Acid; Methylene Chloride; Microspheres; Particle Size; Polyesters; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Solvents	2013
Influence of formulation and process parameters on the characteristics of PLGA-based microparticles with controlled drug release. Ceska a Slovenska farmacie : casopis Ceske farmaceuticke spolecnosti a Slovenske farmaceuticke spolecnosti, 2013, Volume: 62, Issue:3 Topics: Acetates; Chemistry, Pharmaceutical; Delayed-Action Preparations; Drug Liberation; Ibuprofen; Lactic Acid; Methylene Chloride; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Solvents	2013
Glass capillary microfluidics for production of monodispersed poly (DL-lactic acid) and polycaprolactone microparticles: experiments and numerical simulations. Journal of colloid and interface science, 2014, Mar-15, Volume: 418 Topics: Chloroform; Computer Simulation; Drug Compounding; Glass; Kinetics; Lactic Acid; Lidocaine; Methylene Chloride; Microfluidic Analytical Techniques; Microspheres; Models, Statistical; Polyesters; Polymers; Porosity; Rheology; Toluene; Video Recording; Volatilization; Water; Wettability	2014
Long-term controlled release of PLGA microparticles containing antidepressant mirtazapine. Pharmaceutical development and technology, 2016, Volume: 21, Issue:2 Topics: Antidepressive Agents; Delayed-Action Preparations; Drug Liberation; Kinetics; Lactic Acid; Methylene Chloride; Mianserin; Microspheres; Mirtazapine; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Solvents	2016
Influence of different formulations and process parameters during the preparation of drug-loaded PLGA microspheres evaluated by multivariate data analysis. Acta pharmaceutica (Zagreb, Croatia), 2014, Volume: 64, Issue:4 Topics: Acetates; Chemistry, Pharmaceutical; Drug Carriers; Drug Compounding; Excipients; Ibuprofen; Lactic Acid; Methylene Chloride; Microspheres; Multivariate Analysis; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polyvinyl Alcohol; Solubility; Solvents	2014
Electrospraying technique for the fabrication of metronidazole contained PLGA particles and their release profile. Materials science & engineering. C, Materials for biological applications, 2015, Nov-01, Volume: 56 Topics: Cell Proliferation; Cells, Cultured; Delayed-Action Preparations; Drug Carriers; Drug Delivery Systems; Humans; Lactic Acid; Mesenchymal Stem Cells; Methylene Chloride; Metronidazole; Microscopy, Electron, Scanning; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Solvents; Surface Properties; Trifluoroethanol	2015
Pore formation mechanism of porous poly(DL-lactic acid) matrix membrane. Materials science & engineering. C, Materials for biological applications, 2016, Apr-01, Volume: 61 Topics: Cryoelectron Microscopy; Lactic Acid; Methylene Chloride; Phase Transition; Polyesters; Polyethylene Glycols; Polymers; Porosity; Solubility; Solvents; Surface Tension; Tensile Strength; Thermogravimetry	2016
Different methods to determine the encapsulation efficiency of protein in PLGA nanoparticles. Bio-medical materials and engineering, 2017, Volume: 28, Issue:6 Topics: Acetonitriles; Animals; Cattle; Chemical Fractionation; Drug Carriers; Drug Liberation; Fluorescein-5-isothiocyanate; Fluorescence; Iodine Radioisotopes; Lactic Acid; Methylene Chloride; Nanoparticles; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Serum Albumin; Serum Albumin, Bovine; Solvents; Spectrometry, Fluorescence	2017