Page last updated: 2024-08-17

methylene blue and primaquine

methylene blue has been researched along with primaquine in 24 studies

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-199011 (45.83)18.7374
1990's1 (4.17)18.2507
2000's1 (4.17)29.6817
2010's11 (45.83)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Fidock, DA; Flannery, EL; Winzeler, EA1
Barnard, L; Birkholtz, LM; Botha, M; Brunschwig, C; Burrows, JN; Chibale, K; Churchyard, A; Coetzer, TL; Denti, P; Egan, TJ; Laing, L; Lauterbach, S; Machado, M; Ndubi, F; Njogu, PM; Njoroge, M; Nondaba, S; Okombo, J; Prudêncio, M; Reader, J; Singh, K; Wiesner, L; Wilkinson, C; Wittlin, S; Yeates, C1
Bezuidenhout, B; Birkholtz, LM; Chibale, K; Churchyard, A; Coetzer, TL; Egan, TJ; Fontinha, D; Gibhard, L; Lauterbach, S; Mayoka, G; Njoroge, M; Okombo, J; Prudêncio, M; Reader, J; Sanches-Vaz, M; van der Watt, M; Wittlin, S; Yeates, C1
Garfinkel, E; Hirschman, SZ1
Allison, RG; Hahn, FE1
Baird, JK; Canfield, CJ; McCormick, GJ1
Berry, DH; Hochstein, P1
Maronpot, RR1
Lantz, CH; Van Dyke, K1
Ajmar, F; Bianchi, G; Gaetani, G; Garré, C; Salvidio, E1
Davidson, WD; Tanaka, KR1
D'Elia, R; Panizon, F1
Harley, JD1
Arnold, W; Gahl, GM; Hess, G; Meyer zum Büschenfelde, KH; Möller, B1
Aguiar Cruz, F; Hadad Meléndez, P; Martínez, JL; Millán Marcelo, JC1
Khubchandani, RP; Mody, S; Raman, J1
Ahn, S; Kim, WY; Kim, YJ; Lee, JH; Lee, YS; Lim, KS; Oh, BJ; Ryoo, SM; Seo, DW; Sohn, CH1
Belfield, KD; Tichy, EM1
Bousema, T; Bradley, J; Brown, JM; Chen, I; Diarra, K; Diawara, H; Dicko, A; Drakeley, C; Gosling, R; Hwang, J; Issiaka, D; Keita, S; Kone, DT; Lanke, K; Mahamar, A; McCulloch, C; Müller, O; Roh, ME; Sanogo, K; Soumare, HM; Srinivasan, V; Stone, WJR; Traore, SF1
Price, RN; White, NJ1
Kato, K; Mitsui, Y1
Choi, L; Garner, P; Gelband, H; Graves, P1
Bousema, T; Bradley, J; Churcher, TS; Delves, M; Diawara, H; Dicko, A; Drakeley, C; Gosling, R; Mahamar, A; Roh, M; Soumaré, HM1
Compaoré, G; Coulibaly, B; D Alessandro, U; Jahn, A; Kieser, M; Klose, C; Krisam, J; Lu, G; Meissner, P; Mendes Jorge, M; Mockenhaupt, FP; Müller, O; Nebie, E; Ouermi, L; Sié, A1

Reviews

2 review(s) available for methylene blue and primaquine

ArticleYear
Using genetic methods to define the targets of compounds with antimalarial activity.
    Journal of medicinal chemistry, 2013, Oct-24, Volume: 56, Issue:20

    Topics: Animals; Anopheles; Antimalarials; Drug Resistance; Genetic Association Studies; Genome, Protozoan; Humans; Malaria, Falciparum; Molecular Targeted Therapy; Plasmodium falciparum

2013
Review and drug therapy implications of glucose-6-phosphate dehydrogenase deficiency.
    American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 2018, 02-01, Volume: 75, Issue:3

    Topics: Glucosephosphate Dehydrogenase; Glucosephosphate Dehydrogenase Deficiency; Hemolysis; Humans; Methylene Blue; Point-of-Care Systems; Primaquine; Urate Oxidase

2018

Trials

3 trial(s) available for methylene blue and primaquine

ArticleYear
Efficacy and safety of primaquine and methylene blue for prevention of Plasmodium falciparum transmission in Mali: a phase 2, single-blind, randomised controlled trial.
    The Lancet. Infectious diseases, 2018, Volume: 18, Issue:6

    Topics: Adolescent; Adult; Amodiaquine; Artemisinins; Child; Child, Preschool; Drug Combinations; Humans; Malaria, Falciparum; Mali; Methylene Blue; Middle Aged; Plasmodium falciparum; Primaquine; Pyrimethamine; Quinolines; Sulfadoxine; Young Adult

2018
Transmission-blocking Effects of Primaquine and Methylene Blue Suggest Plasmodium falciparum Gametocyte Sterilization Rather Than Effects on Sex Ratio.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2019, 09-27, Volume: 69, Issue:8

    Topics: Adolescent; Adult; Animals; Antimalarials; Child; Child, Preschool; Culicidae; Female; Humans; Malaria, Falciparum; Male; Mali; Methylene Blue; Middle Aged; Plasmodium falciparum; Primaquine; Sex Ratio; Sterilization; Young Adult

2019
Safety and efficacy of artesunate-amodiaquine combined with either methylene blue or primaquine in children with falciparum malaria in Burkina Faso: A randomized controlled trial.
    PloS one, 2019, Volume: 14, Issue:10

    Topics: Amodiaquine; Antimalarials; Artemisinins; Artesunate; Burkina Faso; Child, Preschool; Drug Therapy, Combination; Female; Humans; Malaria, Falciparum; Male; Methylene Blue; Plasmodium falciparum; Primaquine; Treatment Outcome

2019

Other Studies

19 other study(ies) available for methylene blue and primaquine

ArticleYear
Antimalarial Pyrido[1,2-a]benzimidazoles: Lead Optimization, Parasite Life Cycle Stage Profile, Mechanistic Evaluation, Killing Kinetics, and in Vivo Oral Efficacy in a Mouse Model.
    Journal of medicinal chemistry, 2017, 02-23, Volume: 60, Issue:4

    Topics: Animals; Antimalarials; Benzimidazoles; Life Cycle Stages; Malaria; Male; Mice; Plasmodium berghei; Structure-Activity Relationship

2017
Structure-Activity Relationship Studies and Plasmodium Life Cycle Profiling Identifies Pan-Active N-Aryl-3-trifluoromethyl Pyrido[1,2- a]benzimidazoles Which Are Efficacious in an in Vivo Mouse Model of Malaria.
    Journal of medicinal chemistry, 2019, 01-24, Volume: 62, Issue:2

    Topics: Animals; Antimalarials; Benzimidazoles; Disease Models, Animal; Drug Design; ERG1 Potassium Channel; Half-Life; Hemeproteins; Life Cycle Stages; Malaria; Mice; Mice, Inbred C57BL; Plasmodium; Structure-Activity Relationship; Survival Rate

2019
Inhibition of hepatitis B DNA polymerase by intercalating agents.
    Nature, 1978, Feb-16, Volume: 271, Issue:5646

    Topics: Chloroquine; Chlorpromazine; Drug Synergism; Ethidium; Hepatitis B; Hepatitis B virus; Humans; Indicators and Reagents; Methylene Blue; Nucleic Acid Synthesis Inhibitors; Primaquine; Quinacrine

1978
Changes in superhelical density of closed circular deoxyribonucleic acid by intercalation of anti-R-plasmid drugs and primaquine.
    Antimicrobial agents and chemotherapy, 1977, Volume: 11, Issue:2

    Topics: Acridines; Chemical Phenomena; Chemistry; Chloroquine; Chlorpromazine; DNA, Circular; Ethidium; Extrachromosomal Inheritance; Methylene Blue; Plasmids; Primaquine; Pseudomonas; Quinine

1977
Effects of nine synthetic putative metabolites of primaquine on activity of the hexose monophosphate shunt in intact human red blood cells in vitro.
    Biochemical pharmacology, 1986, Apr-01, Volume: 35, Issue:7

    Topics: Aminoquinolines; Erythrocytes; Ethylmaleimide; Glucosephosphate Dehydrogenase Deficiency; Hemolysis; Humans; Methemoglobin; Methylene Blue; Models, Chemical; Oxyhemoglobins; Pentose Phosphate Pathway; Primaquine; Structure-Activity Relationship

1986
Primaquine-induced hemolysis of normal erythrocytes in vitro: the requirement for energy.
    Biochemical medicine, 1970, Volume: 4, Issue:3

    Topics: Adenosine Triphosphatases; Adenosine Triphosphate; Carbon Dioxide; Carbon Isotopes; Cell Membrane; Dinitrophenols; Enzyme Activation; Erythrocytes; Fluorides; Galactose; Glucose; Glutathione; Hemolysis; Humans; Hydrogen Peroxide; Iodoacetates; Lactates; Methylene Blue; Pentosephosphates; Primaquine; Sucrose

1970
Erythrocyte glucose-6-phosphate dehydrogenase and glutathione deficiency in sheep.
    Canadian journal of comparative medicine : Revue canadienne de medecine comparee, 1972, Volume: 36, Issue:1

    Topics: Age Factors; Animals; Chromium Isotopes; Disease Models, Animal; Erythrocytes; Female; Glucosephosphate Dehydrogenase; Glucosephosphate Dehydrogenase Deficiency; Glutathione; Hemolysis; Male; Methylene Blue; Nitrofurantoin; Primaquine; Pyrimethamine; Sex Factors; Sheep

1972
Plasmodium berghei: inhibited incorporation of AMP-8- 3 H into nucleic acids of erythrocyte-free malarial parasites by acridines, phenanthridines, and 8-aminoquinolines.
    Experimental parasitology, 1972, Volume: 31, Issue:2

    Topics: Acridines; Adenine Nucleotides; Adenosine Monophosphate; Amines; Animals; Depression, Chemical; DNA; Heterocyclic Compounds; Methylene Blue; Nucleic Acids; Phenanthridines; Plasmodium; Primaquine; Quinolines; RNA; Structure-Activity Relationship; Tritium

1972
Effect of primaquine on erythrocytes with NADH-methaemoglobin reductase deficiency and low glutathione reductase activity.
    British journal of haematology, 1972, Volume: 23, Issue:3

    Topics: Blood Protein Electrophoresis; Child; Chromium Isotopes; Dihydrolipoamide Dehydrogenase; Erythrocytes; Glutathione Reductase; Hemoglobinometry; Hemolysis; Humans; Male; Methemoglobinemia; Methylene Blue; Primaquine; Riboflavin

1972
Factors affecting pentose phosphate pathway activity in human red cells.
    British journal of haematology, 1972, Volume: 23, Issue:3

    Topics: Ascorbic Acid; Carbon Dioxide; Carbon Isotopes; Culture Media; Erythrocytes; Glucose; Humans; Hydrogen-Ion Concentration; In Vitro Techniques; Metabolism; Methods; Methylene Blue; Oxygen Consumption; Pentosephosphates; Plasma; Primaquine; Radiometry; Stimulation, Chemical; Temperature

1972
[Oxidative hemolysis in the newborn. I. Effects of incubation with oxidizing agents on erythrocyte survival, on reduced glutathione and on formation of Heinz bodies].
    Bollettino della Societa italiana di biologia sperimentale, 1968, Dec-31, Volume: 44, Issue:24

    Topics: Adult; Erythrocyte Aging; Glutathione Reductase; Heinz Bodies; Hemolysis; Humans; Infant, Newborn; Infant, Newborn, Diseases; Methylene Blue; Primaquine; Vitamin K

1968
Significance and regulation of methaemoglobinaemia.
    Nature, 1966, Jun-11, Volume: 210, Issue:5041

    Topics: Aspirin; Erythrocytes; Glutathione; Hemolysin Proteins; Methemoglobin; Methylene Blue; Naphthalenes; Naphthoquinones; Nitrites; Phenacetin; Phenols; Phenylhydrazines; Primaquine; Quinones

1966
Inhibition of hepatitis B virus specific DNA polymerase by intercalating agents.
    Medical microbiology and immunology, 1980, Volume: 168, Issue:1

    Topics: Carrier State; Chloroquine; DNA-Directed DNA Polymerase; Ethidium; Hepatitis B; Hepatitis B Antigens; Hepatitis B virus; Humans; Intercalating Agents; Magnesium; Methylene Blue; Nucleic Acid Synthesis Inhibitors; Primaquine; Quinacrine; Quinine

1980
[Determination of glucose-6-phosphate dehydrogenase deficiency to prevent possible drug-induced hemolysis].
    Revista cubana de medicina tropical, 1991, Volume: 43, Issue:3

    Topics: Anemia, Hemolytic; Antimalarials; Glucosephosphate Dehydrogenase Deficiency; Hemolysis; Humans; Methylene Blue; Primaquine

1991
Primaquine induced methemoglobinemia.
    Indian journal of pediatrics, 2003, Volume: 70, Issue:6

    Topics: Antimalarials; Child; Enzyme Inhibitors; Humans; Methemoglobinemia; Methylene Blue; Primaquine; Treatment Outcome

2003
Difference of the clinical course and outcome between dapsone-induced methemoglobinemia and other toxic-agent-induced methemoglobinemia.
    Clinical toxicology (Philadelphia, Pa.), 2016, Volume: 54, Issue:7

    Topics: Adult; Aged; Aged, 80 and over; Case-Control Studies; Dapsone; Dose-Response Relationship, Drug; Drug Overdose; Emergency Service, Hospital; Female; Humans; Lidocaine; Male; Methemoglobin; Methemoglobinemia; Methylene Blue; Middle Aged; Oxazines; Poisoning; Primaquine; Retrospective Studies; Sodium Nitrite; Treatment Outcome; Young Adult

2016
Drugs that reduce transmission of falciparum malaria.
    The Lancet. Infectious diseases, 2018, Volume: 18, Issue:6

    Topics: Humans; Malaria, Falciparum; Mali; Methylene Blue; Plasmodium falciparum; Primaquine; Single-Blind Method

2018
Application of Non-Fluorescent Dyes to Assess the Antischistosomal Effect of Antimalarial Drugs on Schistosoma mansoni Adult Worms.
    Japanese journal of infectious diseases, 2018, Sep-21, Volume: 71, Issue:5

    Topics: Amodiaquine; Animals; Anthelmintics; Antimalarials; Artesunate; Biological Assay; Female; Male; Methylene Blue; Neutral Red; Parasitic Sensitivity Tests; Primaquine; Schistosoma mansoni; Staining and Labeling; Survival Analysis; Trypan Blue

2018
Gametocytocidal drugs: taking the population perspective.
    The Lancet. Infectious diseases, 2018, Volume: 18, Issue:7

    Topics: Mali; Methylene Blue; Plasmodium falciparum; Primaquine; Single-Blind Method

2018