methylene blue has been researched along with hydromethylthionine in 33 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (12.12) | 18.7374 |
| 1990's | 1 (3.03) | 18.2507 |
| 2000's | 5 (15.15) | 29.6817 |
| 2010's | 14 (42.42) | 24.3611 |
| 2020's | 9 (27.27) | 2.80 |
| Authors | Studies |
|---|---|
| Akoachere, MB; Becker, K; Buchholz, K; Dandekar, T; Eubel, JK; Gromer, S; Schirmer, RH | 1 |
| Huang, SL; Huang, ZS; Liu, ZQ; Lv, P; Wang, N; Xia, CL | 1 |
| Bansal, NK; Deshmukh, AS; Kropp, KA | 1 |
| Babbs, CF; Salaris, SC; Voorhees, WD | 1 |
| Miike, A; Ohishi, N; Ohkawa, H; Tatano, T; Yagi, K | 1 |
| Jensen, HE; Wille-Jørgensen, P | 1 |
| Cohen, M; Kurihara, K; Schultz, RC | 1 |
| Berman, ES; Hallock, AJ; Zare, RN | 1 |
| Baptista, MS; Belisle, E; Gabrielli, D; Kowaltowski, AJ; Severino, D | 1 |
| Borwitzky, H; Burhenne, J; Haefeli, WE | 1 |
| Noubactep, C | 1 |
| Chan, WC; Coghi, P; Fan, KM; Haynes, RK; Li, KY; Melato, S; Monti, D; Prosperi, D; Sung, HH; Williams, ID; Wong, HN; Wu, WK | 1 |
| Achari, G; Izadifard, M; Langford, CH | 1 |
| Chen, MJ; Cheu, KW; Coghi, P; Guo, ZF; Guo, ZH; Haynes, RK; Monti, D; Tang, MM | 1 |
| Ayaz Ahmed, KB; Sivasubramanian, A; Subramanian, S; Veerappan, A; Veerappan, G | 1 |
| Iga, Y; Li, B; Lim, WL; Sakai, H | 1 |
| Clunas, S; Harrington, CR; Harrington, KA; Horsley, D; Ishaq, A; Kemp, SJ; Larch, CP; Marshall, C; Nicoll, SL; Rickard, JE; Simpson, M; Sinclair, JP; Storey, JM; Storey, LJ; Wischik, CM | 1 |
| Wise, J | 1 |
| Ding, J; Hua, K; Jia, L; Tao, X; Zhang, X | 1 |
| Ahearn, T; Bentham, P; Bracoud, L; Davis, CS; Frisoni, GB; Gauthier, S; Hardlund, JH; Harrington, CR; Jia, J; Kook, KA; Marek, K; Moebius, HJ; Riedel, G; Schelter, BO; Seibyl, J; Shamsi, K; Staff, RT; Storey, JMD; Vuksanovic, V; Wilcock, GK; Wischik, CM; Wischik, DJ | 1 |
| Al-Hilaly, YK; Baddeley, T; Harrington, CR; Pollack, SJ; Raulin, AC; Rickard, JE; Schellenberger, P; Serpell, LC; Simpson, M; Storey, JMD; Wischik, CM | 1 |
| Dang, ZS; Gui, WF; Xu, S; Zhao, YM | 1 |
| Lee, HE; Lee, JY; Lim, D; Lim, SM; Pae, AN | 1 |
| Baddeley, TC; Bentham, P; Bracoud, L; Ganesan, H; Gauthier, S; Hammel, J; Harrington, CR; Jia, J; Kook, K; Murray, AD; Riedel, G; Rubino, CM; Schelter, BO; Shiells, H; Staff, RT; Storey, JMD; Vuksanovic, V; Wischik, CM | 1 |
| Bartochowski, Z; Grossberg, GT; Hashweh, NN; Khoury, R | 1 |
| Cranston, A; Harrington, CR; Klein, J; Kondak, C; Lauer, D; Magbagbeolu, M; Melis, V; Niewiadomska, G; Riedel, G; Santos, RX; Schwab, K; Steczkowska, M; Theuring, F; Wischik, CM; Wydrych, M; Zadrozny, M | 1 |
| Baddeley, TC; Bentham, P; Bracoud, L; Ganesan, H; Gauthier, S; Hammel, J; Hardlund, J; Harrington, CR; Jia, J; Kipps, CM; Kook, K; Moebius, HJ; Murray, AD; Riedel, G; Rubino, CM; Schelter, BO; Shiells, H; Staff, RT; Storey, JMD; Vuksanovic, V; Wischik, CM; Wischik, DJ | 1 |
| Bentham, P; Harrington, CR; Schelter, BO; Shiells, H; Staff, RT; Wischik, CM | 1 |
| Harrington, CR; Magbagbeolu, M; Melis, V; Riedel, G; Schwab, K; Theuring, F; Wischik, CM | 1 |
| Harrington, CR; Klein, J; Kondak, C; Riedel, G; Wischik, CM | 1 |
| Kaneta, T; Ren, J | 1 |
| Chasapopoulou, Z; Cranston, A; Frahm, S; Harrington, CR; Magbagbeolu, M; Riedel, G; Schwab, K; Theuring, F; Wischik, CM | 1 |
| Arastoo, M; Harrington, CR; Hull, C; Mazanetz, MP; Miller, S; Robinson, K; Shiells, H; Storey, JMD; Wischik, CM | 1 |
1 review(s) available for methylene blue and hydromethylthionine
| Article | Year |
|---|---|
An evaluation of hydromethylthionine as a treatment option for Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Cognitive Dysfunction; Cohort Studies; Disease Progression; Dose-Response Relationship, Drug; Humans; Methylene Blue; Protein Aggregates; Randomized Controlled Trials as Topic; tau Proteins; Treatment Outcome | 2020 |
4 trial(s) available for methylene blue and hydromethylthionine
| Article | Year |
|---|---|
Leucomethylene blue staining during vagotomy.
Topics: Clinical Trials as Topic; Duodenal Ulcer; Esophagus; Gastric Acid; Humans; Intraoperative Period; Methylene Blue; Recurrence; Staining and Labeling; Vagotomy; Vagotomy, Proximal Gastric | 1981 |
Potential of Low Dose Leuco-Methylthioninium Bis(Hydromethanesulphonate) (LMTM) Monotherapy for Treatment of Mild Alzheimer's Disease: Cohort Analysis as Modified Primary Outcome in a Phase III Clinical Trial.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Antipsychotic Agents; Cohort Studies; Double-Blind Method; Female; Humans; International Cooperation; Male; Mental Status and Dementia Tests; Methylene Blue; Middle Aged; Treatment Outcome | 2018 |
Concentration-Dependent Activity of Hydromethylthionine on Cognitive Decline and Brain Atrophy in Mild to Moderate Alzheimer's Disease.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Atrophy; Brain; Cognitive Dysfunction; Dose-Response Relationship, Drug; Female; Humans; Male; Methylene Blue | 2019 |
Concentration-Dependent Activity of Hydromethylthionine on Clinical Decline and Brain Atrophy in a Randomized Controlled Trial in Behavioral Variant Frontotemporal Dementia.
Topics: Adult; Aged; Atrophy; Brain; Disease Progression; Dose-Response Relationship, Drug; Double-Blind Method; Female; Frontotemporal Dementia; Humans; Magnetic Resonance Imaging; Male; Methylene Blue; Middle Aged; Treatment Outcome | 2020 |
28 other study(ies) available for methylene blue and hydromethylthionine
| Article | Year |
|---|---|
Interactions of methylene blue with human disulfide reductases and their orthologues from Plasmodium falciparum.
Topics: Aerobiosis; Animals; Binding Sites; Disulfides; Humans; Hydrogen-Ion Concentration; Kinetics; Methylene Blue; Oxidation-Reduction; Oxidoreductases; Plasmodium falciparum; Protozoan Proteins; Substrate Specificity | 2008 |
Synthesis and evaluation of 1,2,3,4-tetrahydro-1-acridone analogues as potential dual inhibitors for amyloid-beta and tau aggregation.
Topics: Acridones; Amyloid beta-Peptides; Animals; Blood-Brain Barrier; Central Nervous System Agents; Drug Design; HEK293 Cells; Humans; Microscopy, Confocal; Microscopy, Electron, Transmission; Peptide Fragments; Protein Aggregates; Structure-Activity Relationship; Surface Plasmon Resonance; Swine; Tacrine; tau Proteins | 2018 |
Use of methylene blue in suspected colovesical fistula.
Topics: Colonic Diseases; Enema; Humans; Intestinal Fistula; Intestinal Mucosa; Male; Methylene Blue; Staining and Labeling; Urinary Bladder Fistula | 1977 |
Methylene blue as an inhibitor of superoxide generation by xanthine oxidase. A potential new drug for the attenuation of ischemia/reperfusion injury.
Topics: Animals; Antioxidants; Hypoxanthine; Hypoxanthines; In Vitro Techniques; Kidney; Lipid Peroxidation; Liver; Methylene Blue; Models, Biological; Oxidation-Reduction; Rats; Reperfusion Injury; Succimer; Superoxides; Xanthine; Xanthine Oxidase; Xanthines | 1991 |
A new assay method for lipid peroxides using a methylene blue derivative.
Topics: Colorimetry; Coloring Agents; Lipid Peroxides; Magnetic Resonance Spectroscopy; Mass Spectrometry; Methylene Blue; Spectrophotometry | 1985 |
Nerve staining with leucomethylene blue: an experimental study.
Topics: Animals; Ascorbic Acid; Facial Nerve; Facial Nerve Injuries; Intraoperative Period; Methylene Blue; Models, Biological; Rabbits; Staining and Labeling; Surgery, Plastic; Therapeutic Irrigation; Time Factors | 1984 |
Ultratrace kinetic measurements of the reduction of methylene blue.
Topics: Acetonitriles; Ascorbic Acid; Kinetics; Lasers; Methylene Blue; Optics and Photonics; Oxidation-Reduction; Sensitivity and Specificity; Spectrum Analysis | 2003 |
Binding, aggregation and photochemical properties of methylene blue in mitochondrial suspensions.
Topics: Animals; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Dimerization; Light; Membrane Potentials; Methylene Blue; Mitochondria, Liver; Oxygen; Photochemistry; Photochemotherapy; Rats; Rats, Wistar; Singlet Oxygen; Time Factors | 2004 |
Analysis of methylene blue in human urine by capillary electrophoresis.
Topics: Ascorbic Acid; Calibration; Chromatography, Micellar Electrokinetic Capillary; Electrophoresis, Capillary; Humans; Methylene Blue; Oxidation-Reduction; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization; Urine | 2005 |
Characterizing the discoloration of methylene blue in Fe0/H2O systems.
Topics: Chemical Precipitation; Color; Ferrous Compounds; Kinetics; Methylene Blue; Spectrum Analysis; Water Pollutants, Chemical | 2009 |
Facile oxidation of leucomethylene blue and dihydroflavins by artemisinins: relationship with flavoenzyme function and antimalarial mechanism of action.
Topics: Antimalarials; Artemisinins; Crystallography, X-Ray; Flavins; Glutathione Reductase; Methylene Blue; Molecular Conformation; Oxidation-Reduction; Protozoan Proteins; Reactive Oxygen Species; Structure-Activity Relationship | 2010 |
Photocatalytic dechlorination of polychlorinated biphenyls using leuco-methylene blue sensitization, broad spectrum visible lamps, or light emitting diodes.
Topics: Borohydrides; Catalysis; Chlorine; Environmental Pollutants; Environmental Restoration and Remediation; Halogenation; Lighting; Methylene Blue; Phenothiazines; Photolysis; Polychlorinated Biphenyls; Sunlight | 2010 |
Reactions of antimalarial peroxides with each of leucomethylene blue and dihydroflavins: flavin reductase and the cofactor model exemplified.
Topics: Antimalarials; Flavins; FMN Reductase; Methylene Blue; Models, Theoretical; Peroxides | 2011 |
Preparation of gold nanoparticles using Salicornia brachiata plant extract and evaluation of catalytic and antibacterial activity.
Topics: Aminophenols; Anti-Bacterial Agents; Borohydrides; Catalysis; Chenopodiaceae; Fourier Analysis; Gold; Green Chemistry Technology; Metal Nanoparticles; Methylene Blue; Microscopy, Electron, Scanning; Microscopy, Electron, Transmission; Nitrophenols; Ofloxacin; Plant Extracts; Spectrophotometry, Ultraviolet; Surface Plasmon Resonance; X-Ray Diffraction | 2014 |
Red blood cells donate electrons to methylene blue mediated chemical reduction of methemoglobin compartmentalized in liposomes in blood.
Topics: Animals; Electrons; Erythrocytes; Liposomes; Male; Methemoglobin; Methylene Blue; NAD; NADP; Oxidation-Reduction; Oxygen; Phagocytosis; Rats; Rats, Wistar | 2014 |
Cellular Models of Aggregation-dependent Template-directed Proteolysis to Characterize Tau Aggregation Inhibitors for Treatment of Alzheimer Disease.
Topics: Alzheimer Disease; Animals; Brain; Cell Line; Humans; Methylene Blue; Mice; Mice, Transgenic; Models, Biological; Protein Aggregates; Protein Aggregation, Pathological; Protein Interaction Domains and Motifs; Proteolysis; Recombinant Proteins; tau Proteins | 2015 |
No "breakthrough" in Alzheimer's disease.
Topics: Alzheimer Disease; Humans; Mass Media; Methylene Blue; Randomized Controlled Trials as Topic; tau Proteins; Treatment Failure; United Kingdom; United States | 2016 |
Intraoperative nerve staining in nerve-sparing radical hysterectomy: a pilot study.
Topics: Animals; Autonomic Nervous System; Female; Hysterectomy; Methylene Blue; Pelvis; Pilot Projects; Rats; Rats, Sprague-Dawley; Staining and Labeling; Uterine Cervical Neoplasms | 2017 |
Cysteine-Independent Inhibition of Alzheimer's Disease-like Paired Helical Filament Assembly by Leuco-Methylthioninium (LMT).
Topics: Alzheimer Disease; Cysteine; Heparin; Humans; Methylene Blue; Molecular Structure; Neurofibrillary Tangles; Recombinant Proteins; Spectrum Analysis; tau Proteins | 2018 |
In Vitro and in Vivo Effect of MAPK Signal Transduction Pathway Inhibitors on Echinococcus multilocularis.
Topics: Albendazole; Animals; Anthelmintics; Benzamides; Body Weight; Cell Line; Disease Models, Animal; Echinococcosis; Echinococcus multilocularis; Female; Hepatocytes; Heterocyclic Compounds, 4 or More Rings; Humans; Imidazoles; Inhibitory Concentration 50; Methylene Blue; Mice; Mice, Inbred BALB C; Protein Array Analysis; Protein Kinase Inhibitors; Pyridines; Signal Transduction; Toluene | 2019 |
Recent tau-targeted clinical strategies for the treatment of Alzheimer's disease.
Topics: Acetylation; Alzheimer Disease; Animals; Humans; Methylene Blue; Mice; Salicylates; Severity of Illness Index; tau Proteins | 2019 |
Mechanisms of Anticholinesterase Interference with Tau Aggregation Inhibitor Activity in a Tau-Transgenic Mouse Model.
Topics: Alzheimer Disease; Animals; Brain; Cholinesterase Inhibitors; Disease Models, Animal; Drug Interactions; Methylene Blue; Mice; Mice, Transgenic; Protein Aggregates; Rivastigmine; tau Proteins | 2020 |
Long-Term Hydromethylthionine Treatment Is Associated with Delayed Clinical Onset and Slowing of Cerebral Atrophy in a Pre-Symptomatic P301S MAPT Mutation Carrier.
Topics: Adult; Atrophy; Brain; Carrier State; Frontotemporal Dementia; Humans; Magnetic Resonance Imaging; Male; Methylene Blue; Mutation; tau Proteins; Time Factors | 2021 |
Proteomic Analysis of Hydromethylthionine in the Line 66 Model of Frontotemporal Dementia Demonstrates Actions on Tau-Dependent and Tau-Independent Networks.
Topics: Animals; Female; Frontotemporal Dementia; Immunohistochemistry; Methylene Blue; Mice; Mice, Transgenic; Proteomics; Tandem Mass Spectrometry; tau Proteins | 2021 |
Hydromethylthionine enhancement of central cholinergic signalling is blocked by rivastigmine and memantine.
Topics: Acetylcholine; Acetylcholinesterase; Animals; Cholinesterase Inhibitors; Dopamine Agents; Drug Interactions; Female; Hippocampus; Memantine; Methylene Blue; Mice; Mice, Transgenic; Rivastigmine; Signal Transduction | 2022 |
N-Benzoyl leucomethylene blue as a novel substrate for the assays of horseradish peroxidase by spectrophotometry and capillary electrophoresis-laser-induced fluorometry.
Topics: Electrophoresis, Capillary; Fluorometry; Horseradish Peroxidase; Hydrogen Peroxide; Lasers; Methylene Blue; Oxidation-Reduction; Spectrophotometry | 2022 |
Glutamatergic transmission and receptor expression in the synucleinopathy h-α-synL62 mouse model: Effects of hydromethylthionine.
Topics: alpha-Synuclein; Animals; Glutamates; Humans; Methylene Blue; Mice; Mice, Transgenic; Parkinson Disease; Receptors, N-Methyl-D-Aspartate; Synucleinopathies | 2022 |
Exploring the Anti-Hypoxaemia Effect of Hydromethylthionine: A Prospective Study of Phase 3 Clinical Trial Participants.
Topics: COVID-19; Heme; Humans; Hypoxia; Iron; Methemoglobin; Methylene Blue; Oxygen; Prospective Studies | 2023 |