Page last updated: 2024-08-17

methylene blue and cyclic gmp

methylene blue has been researched along with cyclic gmp in 377 studies

Research

Studies (377)

TimeframeStudies, this research(%)All Research%
pre-199058 (15.38)18.7374
1990's219 (58.09)18.2507
2000's71 (18.83)29.6817
2010's22 (5.84)24.3611
2020's7 (1.86)2.80

Authors

AuthorsStudies
Bogair, N; Golander, A; Spirer, Z; Zakuth, V1
Minakami, S; Nakagawara, A; Takeshige, K1
Blacksin, AS; Clyman, RI; Manganiello, VC; Vaughan, M1
Auguet, M; Braquet, P; Chabrier, PE; Delaflotte, S; Goulin-Schulz, J; Lonchampt, MO2
Kindybalyuk, AM; Kovalenko, TN; Sagach, VF1
Dumont, JE; Esteves, RZ; van Sande, J1
Aronson, WJ; Bush, PA; Dorey, FJ; Ignarro, LJ; Rajfer, J1
Huxley, VH; Meyer, DJ1
Baek, MY; Choi, SW; Kang, MS1
Benessiano, J; Levy, BI; Mourlon-Le Grand, MC1
Akimoto, Y; Jino, H; Kurahashi, K; Usui, H1
Braida, C; Holzmann, S; Kukovetz, WR; Pöch, G2
Koide, T; Sugawa, M; Takato, M1
Gryglewski, RJ; Salvemini, D; Taylor, GW; Vane, JR; Zembowicz, A1
Hata, F; Ishii, T; Kanada, A; Maehara, T; Suthamnatpong, N; Takeuchi, T; Yagasaki, O1
Catravas, JD; Marczin, N; Ryan, US1
Chaudhuri, G; Chiang, K; Fukuto, JM; Hszieh, R; Wong, P1
Bradley, ME; Buxton, IL; Dalziel, HH; Keef, K; Sanders, KM; Ward, SM; Westfall, DP1
Bucher, B; Ouedraogo, S; Paya, D; Stoclet, JC; Tschöpl, M1
Barnes, PJ; Crawley, DE; Evans, TW; Liu, SF; Rohde, JA1
Iwamoto, J; Krasney, E; Krasney, J; Yang, SP; Yoshinaga, M1
Hisayama, T; Moritoki, H; Takeuchi, S; Yoshikawa, T1
Conklin, JL; Du, C; Ledlow, A; Manternach, PL; Murray, JA1
Falk, G; Shiells, R1
Hisayama, T; Kondoh, W; Miyano, H; Moritoki, H; Takeuchi, S1
Papp, JG; Parratt, J; Szekeres, L; Vegh, A1
Baek, WY; Hatano, Y; Mori, K; Nakamura, K; Nishiwada, M; Toda, H1
Ishii, K; Murad, F; Sheng, H1
Hisayama, T; Moritoki, H; Takeuchi, S; Ueda, H; Yamamoto, T1
Cohen, RA; Cowan, CL1
Biondi, ML; Feletou, M; Peglion, JL; Vanhoutte, PM; Vilaine, JP; Villeneuve, N1
Abe, M; Aoyagi, Y; Inoue, M; Morikawa, M; Ohta, A; Tsuboi, M1
Crowley, MR; Fineman, JR; Heymann, MA; Soifer, SJ1
Hamaguchi, M; Imai, S; Ishibashi, T1
Gräser, T; Vanhoutte, PM1
Durante, W; Junquero, DC; Kroll, MH; Schafer, AI; Schini, VB; Scott-Burden, T; Vanhoutte, PM1
Duarte, ID; Ferreira, SH; Lorenzetti, BB1
Pickard, RS; Powell, PH; Zar, MA2
Ali, S; Fiscus, RR; Han, C; Joyce, CD; Murad, F; Wang, X; Zhou, HL1
Komori, S; Ohashi, H; Sugisawa, K; Takewaki, T1
Beasley, D; Brenner, BM; Schwartz, JH1
Torphy, TJ; Zhou, HL1
Cavanaugh, CT; Laychock, SG; Modica, ME1
Beasley, D1
Abiru, T; Kamata, K; Kasuya, Y; Miyata, N1
Ney, P; Schröder, H; Schrör, K; Woditsch, I1
Goy, MF1
Hester, RK; Koibuchi, Y; Matsuo, M; Satake, N; Sato, N; Shibata, S1
Cipkus-Dubray, LA; Hosner, JM; Khan, SA; Meisheri, KD1
Ervens, J; Seifert, R; Wenzel-Seifert, K1
Reiser, G1
Gräser, T; Li, DS; Vedernikov, YP1
Aikawa, J; Akatsuka, N1
Barnes, PJ; Rhoden, KJ1
Archer, SL; Cowan, N; DeMaster, EG; Nelson, DP; Rist, K; Weir, EK1
Endou, M; Hattori, Y; Kanno, M; Nakaya, H1
Hasunuma, K; McMurtry, IF; O'Brien, RF; Rodman, DM; Yamaguchi, T1
Balaraman, V; Easa, D; Hashiro, GM; Kullama, LK; Nakamura, KT; Robillard, JE1
Faunce, D; Henry, D; Lee, DK; Rimele, T; Sturm, RJ1
Fukuzaki, H; Nishimoto, T; Yokoyama, M1
Aubineau, P; Ignarro, L; Lee, J; Pearce, WJ; Reynier-Rebuffel, AM; Seylaz, J1
Chen, CC; Huang, TF; Huang, YL; Teng, CM; Yu, SM1
Boulanger, C; Moncada, S; Schini, VB; Vanhoutte, PM1
Lefer, AM; Osborne, JA; Stahl, GL; Yanagisawa, A1
Hyman, AL; Kadowitz, PJ; Lippton, HL1
Brazdil, R; Diocee, BK; Jordan, R; Souness, JE1
Schini, VB; Vanhoutte, PM1
Burke-Wolin, T; Wolin, MS1
Moummi, C; Rattan, S1
Drazan, KM; Martin, W; Newby, AC1
Barnette, M; Fine, C; Grous, M; Ormsbee, HS; Torphy, TJ1
DeCandido, S; Hays, RM; Satriano, JA; Schlondorff, D; Singhal, PC1
Edwards, BM; Shanahan, MF1
Alheid, U; Förstermann, U; Reichwehr, I1
Miller, RC; Schini, V; Schoeffter, P1
Chiou, WF; Liao, CH; Wu, CC; Yen, MH1
Cohen, ML; Crowe, VG; Kauffman, RF; Schenck, KW; Utterback, BG1
Buga, GM; Byrns, RE; Ignarro, LJ; Wood, KS1
Nelson, GH; Rosenblum, WI; Watanabe, M1
McMurtry, IF; O'Brien, RF; Rodman, DM; Yamaguchi, T1
McKenna, TM1
Chapnick, BM; Ohlstein, EH; Secrest, RJ1
Bol, JG; de Vente, J; Hudson, L; Schipper, J; Steinbusch, HW1
Caramelo, C; Meyer-Lehnert, H; Schrier, RW; Tsai, P1
Kontos, HA; Marshall, JJ; Wei, EP1
Chen, G; Suzuki, H; Weston, AH1
Kukovetz, WR; Schmidt, K1
Burke, TM; Wolin, MS1
Agnost, VL; Bennett, BM; Catalano, RM; Leitman, DC; Murad, F; Schröder, H; Tuan, JJ; Waldman, SA1
Henderson, AH; Martin, W; White, DG1
Campbell, WB; Henrich, WL; McAllister, EA; Smith, PB1
Garthwaite, G; Garthwaite, J1
Furchgott, RF; Jothianandan, D; Martin, W; Villani, GM1
Johnson, RM; Lincoln, TM1
Holzmann, S; Kukovetz, WR2
Ignarro, LJ; Kadowitz, PJ1
Harbison, RG; Hyman, AL; Ignarro, LJ; Kadowitz, PJ; McNamara, DB; Wolin, MS; Wood, KS1
Edwards, DH; Griffith, TM; Henderson, AH; Lewis, MJ1
Murad, F; Rapoport, RM; Schwartz, K; Waldman, SA; Winquist, RJ1
Harbison, RG; Ignarro, LJ; Kadowitz, PJ; Wood, KS1
Matsuoka, I; Nakanishi, H; Sakurai, K1
Hull, SS; Kaiser, L; Sparks, HV1
Abe, K; Hiwatari, M; Kasai, Y; Kohzuki, M; Kudo, K; Omata, K; Sato, M; Takeuchi, K; Tanno, M; Yasujima, M1
Cline, WH; Kolm, P; Lee, TJ; Nickols, GA; Shirasaki, Y; Su, C1
Alosachie, I; Godfraind, T1
Brezinski, ME; Lefer, AM; Smith, JA; Yanagisawa, A1
Byrns, RE; Ignarro, LJ; Wood, KS1
Meyer-Lehnert, H; Schrier, RW; Tsai, P1
Matsuoka, I; Nakanishi, H; Ono, T; Sakurai, K1
Cherry, PD; Furchgott, RF; Jothianandan, D1
DiSalvo, J; Galvas, PE1
Cherry, PD; Furchgott, RF; Jothianandan, D; Zawadzki, JV1
Gruetter, CA; Gruetter, DY; Ignarro, LJ; Kadowitz, PJ; Lyon, JE1
Burkman, AM; Fertel, RH; Keith, RA; Sokoloski, TD2
Holzmann, S; Kukovetz, WR; Pöch, G1
Holzmann, S1
Giles, WR; Han, X; Shimoni, Y1
Beasley, D; McGuiggin, M1
Byam-Smith, M; Garfield, RE; Izumi, H; Yallampalli, C1
Marumo, F; Nonoguchi, H; Owada, A; Sakamoto, H; Terada, Y; Tomita, K1
Damais, C; Drapier, JC; Dugas, B; Kolb, JP; Paul-Eugene, N; Yamaoka, K1
Bolotina, VM; Cohen, RA; Najibi, S; Pagano, PJ; Palacino, JJ1
Oyekan, AO1
Anfossi, G; Cavalot, F; Massucco, P; Mattiello, L; Mularoni, E; Trovati, M1
Hoffman, BJ; Miller, KJ1
Bauer, MB; Gebhart, GF; Murphy, S1
Edvinsson, L; Jansen-Olesen, I; Lassen, NA; Paulson, OB; Wang, Q; You, JP; Zhang, W1
Fukuo, K; Hata, S; Inoue, T; Morimoto, S; Nakahashi, T; Ogihara, T1
Hara, N; Ichinose, M; Sawada, M1
Eneroth, PH; Nilsson, CG; Xiao, L1
Beasley, D; McGuiggin, ME1
Costa, G; García-Pascual, A; Jimenez, E; Labadía, A1
Kuo, SC; Yu, SM1
Gescher, A; Kohl, C; Morgan, P1
Fukutomi, H; Ito, S; Muto, H; Silen, W; Yanaka, A1
Tseng, LF; Xu, JY2
D'Alecy, LG; Jin, JS; Webb, RC1
Garfield, RE; Izumi, H1
Barnes, PJ; Belvisi, MG; Tadjkarimi, S; Ward, JK; Yacoub, MH1
Hughes, H; Joly, GA; Schini, VB; Vanhoutte, PM1
Balligand, JL; Kelly, RA; Marsden, PA; Michel, T; Smith, TW1
Brunner, F; Mayer, B; Schmidt, K1
Spessert, R1
Gray, GA; Paya, D; Stoclet, JC1
Drögemüller, A; Mülsch, A; Schmitz, W; Scholz, H; Stein, B1
Gryglewski, RJ; Hatchett, RJ; Jakubowski, AM; Zembowicz, A1
Alberti, C; Ferretti, S; Frattini, A1
Abu-Kishk, RA; D'Aloia, MA; Lush, DJ; Noble, AR; Williams, BC1
Chi, OZ; Tse, J; Wei, HM; Weiss, HR1
Ando, M; Fujita, K; Kusudo, S; Nagata, Y; Tatematsu, T1
De Koster, BM; Elferink, JG1
Fukushima, T; Ohrui, T; Okinaga, S; Sasaki, H; Sekizawa, K; Yamaya, M1
Izawa, T; Izumi, H; Jinno, Y; Ogawa, N; Okada, Y; Yokoyama, T1
Billiar, TR; Harbrecht, BG; Simmons, RL; Wang, SC1
Dykstra, LA; Fecho, K; Lysle, DT; Maslonek, KA1
Broulik, PD; Schreiber, V1
Dray, A; Patel, IA; Rueff, A; Urban, L1
Illiano, S; Mombouli, JV; Olmos, L; Vanhoutte, PM1
Lee, YS; Wurster, RD1
Imai, S; Ishibashi, T; Kato, K; Kawada, T; Sasage, H1
Oztürk, Y1
Bauer, MB; Gebhart, GF; Murphy, S; Simmons, ML1
Ballejo, G; da Silva, SV; da Silva, VJ; Salgado, HC; Salgado, MC1
Hsu, GL; Lue, TF; Martinez-Piñeiro, L; Tanagho, EA; Trigo-Rocha, F; von Heyden, B1
Anderson, DR; Haefliger, IO; Zschauer, A1
Brian, JE; Hicks, KK; Kennedy, RH; Seifen, E1
Robinson, PJ; Smith, R; Sun, K1
Ando, J; Kamiya, A; Korenaga, R; Toyo-oka, T; Yang, W1
Andersson, KE; Persson, K1
Satake, N; Shibata, S; Zhou, Q1
Iwamoto, ET; Marion, L1
Harrington, CA; Mobley, SL; Wenk, GL1
Baribeau, J; Johnstone, MT; Lacoste, L; Lam, JY; Théroux, P; Waters, D1
Blaschke, TF; Haefeli, WE; Hoffman, BB; Kongpatanakul, S; Srivastava, N1
Layes, E; Spessert, R; Vollrath, L1
Coca-Prados, M; Danziger, RS; DeSantis, L; Matsumoto, S; Pang, IH; Star, RA1
Hashimoto, M; Ishida, Y; Masumura, S; Sakuma, I; Tanaka, Y1
Kosakai, K; Nimura, M; Satake, N; Shibata, S; Zhou, Q1
Donatucci, CF; Hsu, GL; Lue, TF; Martinez-Piñeiro, L; Tanagho, EA; Trigo-Rocha, F1
Jahodová, J; Nedvídková, J; Schreiber, V2
Francis, S; Keaney, JF; Loscalzo, J; Loscalzo, JF; Puyana, JC; Stamler, JS1
Chiba, S; Horiuchi, A; Iwatsuki, K; Ren, LM1
Kubes, P1
Jones, KA; Katusić, ZS; Lorenz, RR; Sieck, GC; Warner, DO1
Chen, X; Gillis, CN1
Descombes, JJ; Laubie, M; Mennecier, P; Porro de Bailliencourt, J; Simonet, S; Verbeuren, TJ1
Aronson, WJ; Hohenfellner, M; Ignarro, LJ; Lue, TF; Rajfer, J; Trigo-Rocha, F1
Fleming, I; Gray, GA; Stoclet, JC1
Okamoto, K; Sakuta, H; Watanabe, Y1
Hisayama, T; Kondoh, W; Miyano, H; Moritoki, H; Takeuchi, S; Yamaguchi, M1
Kawabata, A; Takagi, H; Umeda, N1
Gao, Y; Vanhoutte, PM1
Kinoshita, M; Matsumoto, T; Okamura, T; Toda, N1
Chijiiwa, Y; Kabemura, T; Kawakami, O; Misawa, T; Nawata, H1
Förstermann, U; Ishii, K; Murad, F; Sheng, H1
Delgado, R; Fratelli, M; Galli, G; Ghezzi, P; Rolland, Y; Zinetti, M1
Hentall, ID1
Chang, KC; Choi, SK; Chung, BH1
Croxton, TL; Hirshman, CA; Yamakage, M1
Chuman, H; Chuman, T; Nao-i, N; Sawada, A; Wada, A; Yamamoto, R1
Hisamochi, K; Raikar, BL; Raikar, GV; Schaff, HV1
Eneroth, P; Xiao, L1
Bland-Ward, P; Curtis, MJ; Moore, PK; Pabla, R1
Alzola, ES; Azula, FJ; Conde, M; Macarulla, JM; Marino, A; Trueba, M1
Hirafuji, M; Minami, M; Nezu, A; Shinoda, H1
Dik, IE; Folkerts, G; Henricks, PA; Nijkamp, FP; Sadeghi-Hashjin, G; Van de Loo, PG; Van der Linde, HJ1
de Koster, BM; Elferink, JG; VanSteveninck, J; VanUffelen, BE1
Chen, YL; Messina, EJ; Wolin, MS1
Kamata, K; Kasuya, Y; Kohzuki, M1
Coceani, F; Kelsey, L; Seidlitz, E1
Anfossi, G; Cavalot, F; Hahn, AW; Massucco, P; Mattiello, L; Mularoni, EM; Trovati, M1
Capasso, F; Izzo, AA; Maiolino, P; Mascolo, N1
Guo, X; Kedem, J; Roitstein, A; Scholz, PM; Tse, J; Weiss, HR1
Kanagawa, A; Morita, T; Shimada, Y; Ueki, H1
Davis, P; Gossell, M; Powell, N; Simon, OR1
Christensen, ST; Kemp, K; Quie, H; Rasmussen, L1
Ball, SS; Carrasco, V; Dais, CG; Pillsbury, HC; Prazma, J; Zdanski, C1
Abman, SH; Fox, JJ; Halbower, AC; Ivy, DD; Kinsella, JP; Ziegler, JW1
Ayajiki, K; Kangawa, K; Okamura, T; Toda, N1
Holthusen, H1
Joyner, RW; Kumar, R; Namiki, T1
Andersson, KE; Ny, L; Persson, K; Werkström, V1
Higasa, S; Kakishita, E; Oku, KI; Seto, T; Suehiro, A; Yoshimoto, H1
Arakawa, T; Fujiwara, Y; Fukuda, T; Higuchi, K; Inoue, M; Kobayashi, K; Uno, H; Yu, H1
Barthó, L; Lefebvre, RA1
Sun, W; Wainwright, CL1
Cobbe, SM; Kane, KA; Martynyuk, AE; Rankin, AC1
Guo, X; Kedem, J; Naim, KL; Sadoff, J; Scholz, P; Weiss, HR1
Kinoshita, M; Liu, Q; Matsumoto, T; Nakae, I; Omura, T; Takahashi, M; Takaoka, A1
Castañeda, J; González, C; López-López, JR; Tamayo, L1
Ishiguro, S; Matsuyama, T; Nishio, A; Sakaguchi, H1
Azuma, C; Hashimoto, K; Kimura, T; Koyama, M; Nobunaga, T; Saji, F; Samejima, Y; Sawai, K; Takemura, M1
Kress, M; Petersen, M; Reeh, PW1
Elferink, JG; VanSteveninck, J; VanUffelen, BE1
Azuma, H; Goto, M; Ishida, A; Kamikawatoko, S; Masuda, H; Tamaoki, S; Tokoro, T1
Elustondo, PA; González Bosc, LV; Ortiz, MC; Vidal, NA1
Gibbs, SM; Truman, JW1
Burstyn, JN; Dierks, EA1
Jones, KA; Stuart-Smith, K; Warner, DO1
Fujiki, H; Hata, F; Hirano, T; Miyakoda, G; Mori, T; Nakaya, Y; Ohura, M; Orito, K; Satake, H; Sumida, T; Takeuchi, T; Yamamura, Y; Yoshida, K1
Bina, S; Hart, JL; Jing, M; Ling, GS; Muldoon, SM1
Inoue, T; Mashimo, T; Shibata, M; Shibuta, S; Yoshiya, I1
Fedorovich, SV; Mongin, AA; Nedvetsky, PI1
Jones, KA; Pabelick, C; Perkins, WJ; Warner, DO1
Alborch, E; Barberá, MD; Centeno, JM; Ortí, M; Salom, JB; Torregrosa, G1
Leone, RJ; Scholz, PM; Weiss, HR1
Abe, K; Inoue, R; Ito, Y; Morita, H; Teramoto, N; Waniishi, Y1
Oriowo, MA; Williams, KI; Yousif, MH1
Kaufmann, M; Lang, MG; Liu, R; Lüscher, TF1
Barber, JE; Bradley, KK; Bradley, ME; Buxton, IL; McGaw, T1
Block, ER; Gelband, CH; Li, YD; Martens, JR; Patel, JM; Raizada, MK1
Hwang, TL; Teng, CM; Wu, CC1
Brar, R; Dee, L; Khadour, F; Kumar, A; Parrillo, JE; Schulz, R; Skorupa, G; Wang, P1
Milla, PJ; Rolfe, VE1
Leone, RJ; Naim, KL; Rabindranauth, P; Scholz, PM; Tse, J; Weiss, HR1
Akashi, K; Asayama, J; Kawahara, A; Keira, N; Kobara, M; Matoba, S; Nakagawa, M; Tatsumi, T1
Kawana, S; Miyamoto, A; Namiki, A; Ohshika, H; Yamamoto, S1
Dong, S; Su, J; Tang, C; Zhang, L; Zhang, Z; Zheng, S1
Kaye, DM; Kelly, RA; Wiviott, SD1
Dasso, M; Rosenzweig, S; Spielman, AI; Yan, W1
Cao, LX; Shen, E1
Chen, SJ; Wu, CC; Yen, MH1
Kondo, I; Masaki, E1
Huang, MW; Leone, RJ; Scholz, PM; Tse, J; Weiss, HR1
Lin, JH; Lin, MT; Pan, SP; Yang, YL1
Budelmann, BU; Tu, Y2
Furchgott, RF1
Fukuda, S; Predescu, DN; Schmid-Schönbein, GW; Yasu, T1
Ishida, Y; Momose, K; Tomoda, A1
Hossany, R; Subratty, AH1
Crews, JK; Granger, JP; Herrington, JN; Khalil, RA1
Horikoshi, E; Kamata, A; Takizawa, T1
Ririe, DG; Roberts, PR; Shouse, MN; Zaloga, GP1
Cury, Y; Giorgi, R; Picolo, G1
Castro Resende, AC; Leão, MC; Lima, AF; Mesquita Ferreira, AG; Moreira, CF; Nunes, FR; Sena, KM; Silveira, SS; Soares de Moura, RS1
Eardley, I; Joyce, AD; Minhas, S; Morrison, JB1
Gaudette, GR; Horimoto, H; Krukenkamp, IB; Saltman, AE1
Duarte, ID; Ferreira, SH1
Chang, MS; Chen, CC; Chen, SA; Chiang, CE; Ding, PY; Lin, YC; Luk, HN1
Abacioğlu, N; Akbulut, E; Cakici, I; Tunçtan, B1
Furukawa, S; Hiramatsu, M; Kameyama, T; Karasawa, K; Mamiya, T; Nabeshima, T; Noda, A; Noda, Y; Yamada, K1
Fushiki, S; Itoh, H; Kawa, T; Miki, S; Morimoto, S; Nakagawa, M; Nakamura, K; Nakata, T; Sasaki, S; Takeda, K1
Konev, SV; Mongin, AA; Nedvetsky, PI; Petrenko, SV; Rakovich, AA1
Atucha, NM; Fortepiani, LA; García-Estañ, J; Martínez-Prieto, C; Nadal, FJ; Ortíz, MC1
Lee, SS; Liu, H; Song, D1
Joa, JC; Liu, DD; Tsai, LM; Wu, HL; Yang, JM; Yang, SN1
Angielski, S; Jankowski, M; Kalinowski, L; Szczepanska-Konkel, M1
Caldarera, CM; Clô, C; Facchini, A; Fattori, M; Flamigni, F; Giordano, E; Pignatti, C; Stefanelli, C; Tantini, B1
Amarillo, Y; Moreno, H; Nadal, MS; Rudy, B; Vega-Saenz de Miera, E1
Minami, K; Nakashima, Y; Sata, T; Segawa, K; Shiga, Y; Shigematsu, A; Shiraishi, M1
Cummings, JJ; Wang, H1
Bester, AM; Harvey, BH1
Jain, NK; Kulkarni, SK; Patil, CS; Singh, A1
Kawamura, H; Puro, DG; Sakagami, K; Wu, DM1
Chen, IJ; Chiang, LC; Lin, CY; Lin, RJ; Shen, KP; Wu, BN1
Lamonaca, D; Tiboni, GM1
Agha, AM; Taha, RA1
Abacioğlu, N; Akbulut, E; Cakici, I; Kanzik, I; Tunçtan, B; Uludağ, O1
McKoy, ML; Simon, OR1
Branco, LG; Steiner, AA1
Gurib, FB; Subratty, AH1
Baumann, J; Bellamy, MC; Gedney, JA; Koelzow, H; Snook, NJ1
Ahn, HY; Fang, LH; Hong, JT; Kim, TJ; Kim, Y; Lee, CK; Park, YS; Yun, YP; Zhang, YH1
Tsuchida, K; Watajima, H1
Dalio, MB; Evora, PR; Viaro, F1
Amarante, LH; Duarte, ID1
Gemlik, I; Karamanlioglu, B; Memis, D; Pamukcu, Z; Yuksel, M1
Fujimoto, S; Mori, M; Tsushima, H1
Ayoubi, JM; Dilaï, N; Fanchin, R; Hoffmann, P; Pons, JC; Stanke-Labesque, F1
Hama, H; Yamaguchi, K1
Horimoto, H; Mieno, S; Nomura, Y; Okawa, H; Shinjiro, S; Yoshida, M1
Chen, CJ; Chen, JS; Chen, LW; Hsu, CM; Hwang, YC; Wang, JS1
Duan, Y; Haugabook, SJ; Muller, KJ; Sahley, CL1
Duarte, NM; Evora, PR; Oliveira Neto, AM; Viaro, F; Vicente, WV1
Jun, CH; Lee, TS; Sohn, UD1
Sadan, G; Tasatargil, A1
Jain, NK; Kulkarni, SK; Patil, CS; Singh, VP1
Arulkumaran, S; Hamoud, H; Khan, RN; Warren, A; Wong, LF1
Ekerhovd, E; Norström, A1
Bagcivan, I; Cetin, A; Cetin, M; Demirkoprulu, N; Karadas, B; Kaya, T; Soydan, AS1
Assreuy, J; Barja-Fidalgo, C; da Silva-Santos, JE; Duma, D; Fernandes, D; Villela, CG1
Castañeda-Hernández, G; Castro-Olguín, J; Ortiz, MI; Peña-Samaniego, N1
Basseda, Z; Dehpour, AR; Esmaeili, B; Orandi, AH; Tahsili-Fahadan, P; Yahyavi-Firouz-Abadi, N1
Dehpour, AR; Ebrahimi, F; Homayoun, H; Rafiei-Tabatabaei, N; Riazi, K; Roshanpour, M1
Kulkarni, SK; Padi, SV; Patil, CS; Singh, VP1
Abdullah, FC; Balakhrisnan, G; Jais, AM; Jayaraman, KV; Somchit, MN; Sulaiman, MR; Zakaria, ZA1
Cao, LH; Choi, DH; Kang, DG; Kim, JS; Kim, SJ; Lee, H; Lee, HS; Lee, JK1
Almeida, A; Caillleaux, S; Figueiredo, MR; Kaplan, MA; Lessa, MA; Pimenta, D; Tibiriçá, E1
De Laurentiis, A; Dees, W; Fernández-Solari, J; McCann, SM; Mohn, C; Prestifilippo, JP; Rettori, V1
Achike, FI; Ajay, M; Mustafa, MR1
Almeida, JA; Bihari, D; Cranney, GB; Galhenage, S; Kim, R; Liu, J; Riordan, SM; Thomas, PS; Wegner, EA1
Basile Filho, A; Basseto, S; Capellini, VK; Evora, PR; Rodrigues, AJ; Vicente, WV; Vicente, YA1
da-Silva, CA; Del Bel, EA; Echeverry, MB; Ferreira, FR; Salgado, ML1
Kaneko, K; Tsuchida, K1
Abacioglu, N; Altug, S; Tunctan, B; Uludag, O; Zengil, H1
Branco, LG; Nascimento, CG1
Bose, R; Cheng, ZQ; Jacobs, H; Kasian, K; Light, RB; Mink, SN; Santos Martinez, LE1
Feitosa, RL; Lemos, MC; Matsuda, NM1
Brocardo, Pde S; Budni, J; Kaster, MP; Lobato, KR; Rodrigues, AL1
Assreuy, J; Barja-Fidalgo, C; Fernandes, D; Heckert, BT; Lobo, AR; Nardi, GM; Pacheco, LK; Sordi, R; Villela, CG1
Calixto, AV; De Lima, TC; Duarte, FS; Duzzioni, M; Faria, MS; Nascimento Häckl, LP1
Bahremand, A; Dehpour, AR; Hedayat, T; Nasrabady, SE; Payandemehr, B; Rahimian, R; Ziai, P1
Dai, Y; Hou, Z; Kong, L; Lu, D; Song, J; Wang, F; Wang, X; Xu, H; Xu, Z1
Lu, J; Shi, R; Wang, W; Wei, X; Yang, Y; You, J1
Akhtar, MN; Akira, A; Israf, DA; Khalid, MH; Khalivulla, SI; Lajis, N; Mohamad, AS; Ong, HM; Perimal, EK; Sulaiman, MR; Zareen, S1
Hoffman, RS; Jang, DH; Nelson, LS2
Kondapaneni, M; Laubach, VE; McGregor, JR; Salvemini, D; Samlowski, WE; Tharkar, S1
Dhingra, D; Gilhotra, N1
Dhir, A; Kulkarni, SK1
Kang, YH; Morgan, KG; Shin, HM; Yang, IJ1
Bu, Y; Choi, HY; Ham, I; Kim, H; Lee, K; Lee, M; Yang, G1
Beiras-Fernandez, A; Bogert, NV; Guo, F; Meybohm, P; Moritz, A; Stock, UA; Werner, I1
Imam, MZ; Moniruzzaman, M1
Ghorbanzadeh, B; Hemmati, AA; Mansouri, MT; Mard, SA; Naghizadeh, B; Rezaie, A1
Liao, ZL; Qiu, YJ; Tan, YF; Yu, EY; Zhu, JP1
Dehpour, AR; Imran Khan, M; Norouzi-Javidan, A; Ostadhadi, S1
Barbosa Evora, PR1
Delport, A; Harvey, BH; Petzer, A; Petzer, JP1
Chamanara, M; Dehpour, AR; Nikoui, V; Norouzi-Javidan, A; Ostadhadi, S; Shakiba, S; Zolfaghari, S1
Koizumi, K; Nabeta, R; Nakamura, Y; Oka, JI; Sasaki-Hamada, S1
Hendiani, S; Kashef, N; Rybtke, ML; Tolker-Nielsen, T1
Arcêncio, L; Barbosa Evora, PR; Basile-Filho, A; Fernandes Molina, CA; Mente, ED; Miranda, LE; Rubens de Nadai, T; Sumarelli Albuquerque, AA1
Albuquerque, AAS; Capellini, VK; Carvalho, MTM; Celotto, AC; Evora, PRB; Ferreira, LG1
Duangjai, A; Muanprasat, C; Rukachaisirikul, V; Srimaroeng, C; Sukpondma, Y1
Chen, G; Lou, X; Xue, J1
da Motta, KP; Luchese, C; Martins, CC; Reis, AS; Wilhelm, EA1
Khodayar, MJ; Mohtadi, S; Rahemi, M; Rajabi Vardanjani, H1
Bederska-Łojewska, D; Bielecka-Papierz, G; Jakóbczuk, M; Listos, J; Orzelska-Górka, J; Poleszak, E; Serefko, A; Szewczyk, B; Szopa, A; Szponar, J; Talarek, S; Turek, J1

Reviews

7 review(s) available for methylene blue and cyclic gmp

ArticleYear
The pharmacological and physiological role of cyclic GMP in vascular smooth muscle relaxation.
    Annual review of pharmacology and toxicology, 1985, Volume: 25

    Topics: Acetylcholine; Animals; Arachidonic Acid; Arachidonic Acids; Cyclic GMP; Drug Tolerance; Humans; In Vitro Techniques; Mercaptoethanol; Methylene Blue; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; Nitroso Compounds; Prostaglandins; S-Nitrosothiols; Vasodilation

1985
Endothelium-dependent responses: the last three years.
    Bibliotheca cardiologica, 1984, Issue:38

    Topics: Acetylcholine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Calcimycin; Cyclic GMP; Endothelium; Fatty Acids, Unsaturated; Hemoglobins; Methylene Blue; Norepinephrine; Vasodilation

1984
Endothelial cells as mediators of vasodilation of arteries.
    Journal of cardiovascular pharmacology, 1984, Volume: 6 Suppl 2

    Topics: Acetylcholine; Animals; Arachidonic Acid; Arachidonic Acids; Arteries; Calcimycin; Cyclic GMP; Endothelium; Fatty Acids; Hemoglobins; Humans; Methylene Blue; Muscle Relaxation; Muscle, Smooth, Vascular; Vasodilation

1984
[Role of nitric oxide in the erectile mechanism].
    Minerva urologica e nefrologica = The Italian journal of urology and nephrology, 1993, Volume: 45, Issue:2

    Topics: Amino Acid Oxidoreductases; Calcium; Cyclic GMP; Endothelium, Vascular; Erectile Dysfunction; Humans; Male; Methylene Blue; Neurotransmitter Agents; Nitric Oxide; Nitric Oxide Synthase; Penile Erection; Penis; Priapism; Signal Transduction; Vasodilation

1993
Cell death, survival and proliferation in Tetrahymena thermophila. Effects of insulin, sodium nitroprusside, 8-Bromo cyclic GMP, NG-methyl-L-arginine and methylene blue.
    Cell biology international, 1996, Volume: 20, Issue:10

    Topics: Animals; Cattle; Cell Count; Cell Division; Cell Survival; Culture Media; Cyclic GMP; Drug Synergism; Evolution, Molecular; Guanylate Cyclase; Hemin; Humans; Insulin; Methylene Blue; Nitric Oxide; Nitroprusside; omega-N-Methylarginine; Recombinant Proteins; Reproduction; Signal Transduction; Tetrahymena thermophila

1996
Methylene blue for distributive shock: a potential new use of an old antidote.
    Journal of medical toxicology : official journal of the American College of Medical Toxicology, 2013, Volume: 9, Issue:3

    Topics: Anaphylaxis; Animals; Antidotes; Cyclic GMP; Drug Resistance; Endothelium, Vascular; Enzyme Inhibitors; Humans; Isoenzymes; Methylene Blue; Models, Biological; Muscle, Smooth, Vascular; Nitric Oxide; Nitric Oxide Synthase; Second Messenger Systems; Sepsis; Shock; Shock, Cardiogenic; Vascular Resistance

2013
[Research progress of methylene blue in the treatment of sepsis and septic shock].
    Zhonghua wei zhong bing ji jiu yi xue, 2021, Volume: 33, Issue:11

    Topics: Cyclic GMP; Guanylate Cyclase; Humans; Methylene Blue; Nitric Oxide; Sepsis; Shock, Septic

2021

Trials

4 trial(s) available for methylene blue and cyclic gmp

ArticleYear
Involvement of the NO/cyclic GMP pathway in bradykinin-evoked pain from veins in humans.
    Pain, 1997, Volume: 69, Issue:1-2

    Topics: Adult; Bradykinin; Cyclic GMP; Hand; Humans; Male; Methylene Blue; Nitric Oxide; Pain; Pain Measurement; Regional Blood Flow; Signal Transduction; Veins

1997
The effect of methylene blue on the hemodynamic changes during ischemia reperfusion injury in orthotopic liver transplantation.
    Anesthesia and analgesia, 2002, Volume: 94, Issue:4

    Topics: Blood Pressure; Cardiac Output; Central Venous Pressure; Cyclic GMP; Enzyme Inhibitors; Female; Guanylate Cyclase; Hemodynamics; Humans; Lactic Acid; Liver Cirrhosis; Liver Transplantation; Male; Methylene Blue; Middle Aged; Nitrites; Reperfusion; Reperfusion Injury; Vascular Resistance; Vasoconstrictor Agents

2002
The influence of methylene blue infusion on cytokine levels during severe sepsis.
    Anaesthesia and intensive care, 2002, Volume: 30, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Cyclic GMP; Cytokines; Double-Blind Method; Enzyme Inhibitors; Female; Hemodynamics; Humans; Infusions, Intravenous; Interleukins; Male; Methemoglobin; Methylene Blue; Middle Aged; Prospective Studies; Sepsis; Tumor Necrosis Factor-alpha

2002
Methylene blue modulates transendothelial migration of peripheral blood cells.
    PloS one, 2013, Volume: 8, Issue:12

    Topics: Apoptosis; Cells, Cultured; Cyclic GMP; Endothelial Cells; Enzyme Inhibitors; Erythrocytes; Gene Expression Regulation, Enzymologic; Humans; Leukocytes, Mononuclear; Male; Methylene Blue; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Transendothelial and Transepithelial Migration

2013

Other Studies

366 other study(ies) available for methylene blue and cyclic gmp

ArticleYear
The influence of cyclic nucleotides (c-AMP and c-GMP) on the nitrous blue tetrazolium reduction by human polymorphonuclear leucocytes.
    Experientia, 1975, Jan-15, Volume: 31, Issue:1

    Topics: Ascorbic Acid; Coloring Agents; Cyclic AMP; Cyclic GMP; Drug Antagonism; Endotoxins; Humans; Leukocytes; Methylene Blue; Oxidation-Reduction; Phagocytosis; Tetrazolium Salts; Theophylline

1975
Effect of cyclic nucleotides on the cyanide-insensitive respiration of polymorphonuclear leucocytes.
    Journal of biochemistry, 1975, Volume: 77, Issue:3

    Topics: Animals; Bucladesine; Cyanides; Cyclic AMP; Cyclic GMP; Escherichia coli; Guinea Pigs; In Vitro Techniques; Leukocytes; Methylene Blue; Microsomes, Liver; Myristic Acids; Nucleotides, Cyclic; Oxygen Consumption; Phagocytosis; Rats; Theophylline; Trypsin

1975
Oxygen and cyclic nucleotides in human umbilical artery.
    Proceedings of the National Academy of Sciences of the United States of America, 1975, Volume: 72, Issue:10

    Topics: Anaerobiosis; Ascorbic Acid; Bradykinin; Calcimycin; Calcium; Cyclic AMP; Cyclic GMP; Dinitrophenols; Female; Histamine; Humans; Methylene Blue; Oligomycins; Oxidative Phosphorylation; Oxygen Consumption; Pregnancy; Prostaglandins E; Umbilical Arteries

1975
Lipoteichoic acid: a new inducer of nitric oxide synthase.
    Journal of cardiovascular pharmacology, 1992, Volume: 20 Suppl 12

    Topics: Amino Acid Oxidoreductases; Animals; Aorta; Arginine; Cells, Cultured; Cyclic GMP; Endothelium, Vascular; Enzyme Induction; Lipopolysaccharides; Methylene Blue; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Rats; Teichoic Acids; Vasoconstriction

1992
Functional hyperemia of skeletal muscle: role of endothelium.
    Journal of cardiovascular pharmacology, 1992, Volume: 20 Suppl 12

    Topics: Animals; Arginine; Child; Cyclic GMP; Dogs; Electric Stimulation; Endothelium, Vascular; Gossypol; Humans; Indomethacin; Isometric Contraction; Methylene Blue; Muscles; Nitric Oxide; Regional Blood Flow

1992
Nitric oxide as a signal in thyroid.
    Molecular and cellular endocrinology, 1992, Volume: 90, Issue:1

    Topics: Amino Acid Oxidoreductases; Animals; Arginine; Calcimycin; Calcium; Carbachol; Cyclic GMP; Dogs; Enzyme Activation; Guanylate Cyclase; Methylene Blue; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; omega-N-Methylarginine; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositols; Receptors, Muscarinic; Signal Transduction; Thyroid Gland

1992
Nitric oxide as a mediator of relaxation of the corpus cavernosum in response to nonadrenergic, noncholinergic neurotransmission.
    The New England journal of medicine, 1992, Jan-09, Volume: 326, Issue:2

    Topics: Adult; Aged; Arginine; Cyclic GMP; Electric Stimulation; Erectile Dysfunction; Humans; Male; Methylene Blue; Middle Aged; Muscle Relaxation; Muscle, Smooth; Nitric Oxide; Nitroarginine; Organ Culture Techniques; Penile Erection; Penis; Purinones; Synaptic Transmission

1992
Capillary hydraulic conductivity is elevated by cGMP-dependent vasodilators.
    Circulation research, 1992, Volume: 70, Issue:2

    Topics: Animals; Atrial Natriuretic Factor; Capillaries; Cyclic GMP; Drug Synergism; Methylene Blue; Nitroprusside; Purinones; Rana pipiens; Vasodilator Agents

1992
Involvement of cyclic GMP in the fusion of chick embryonic myoblasts in culture.
    Experimental cell research, 1992, Volume: 199, Issue:1

    Topics: Animals; Calcimycin; Calcium; Cell Fusion; Cells, Cultured; Chick Embryo; Creatine Kinase; Cyclic GMP; Dose-Response Relationship, Drug; Gallopamil; Kinetics; Methylene Blue; Muscles

1992
cGMP pathway and mechanical properties of carotid artery wall in WKY rats and SHR: role of endothelium.
    The American journal of physiology, 1992, Volume: 263, Issue:1 Pt 2

    Topics: Animals; Carotid Arteries; Cyclic GMP; Endothelium, Vascular; Methylene Blue; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Vascular Resistance

1992
Nifedipine-resistant Ca(++)-induced contraction in tail artery of spontaneously hypertensive rats.
    Life sciences, 1992, Volume: 51, Issue:9

    Topics: Animals; Arteries; Blood Pressure; Calcium; Cyclic GMP; Egtazic Acid; In Vitro Techniques; Male; Methylene Blue; Muscle Contraction; Muscle, Smooth, Vascular; Nifedipine; Nitroglycerin; Norepinephrine; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Serotonin

1992
Pharmacological interaction experiments differentiate between glibenclamide-sensitive K+ channels and cyclic GMP as components of vasodilation by nicorandil.
    European journal of pharmacology, 1992, Apr-29, Volume: 215, Issue:1

    Topics: Animals; Benzopyrans; Cattle; Coronary Vessels; Cromakalim; Cyclic GMP; Drug Interactions; Glyburide; Guanidines; In Vitro Techniques; Methylene Blue; Molsidomine; Muscle Relaxation; Niacinamide; Nicorandil; Nitroprusside; Pinacidil; Potassium Channels; Pyrroles; Sensitivity and Specificity; Vasodilator Agents

1992
BY-1949 elicits vasodilation via preferential elevation of cyclic GMP levels within the cerebral artery: possible involvement of endothelium-mediated mechanisms.
    European journal of pharmacology, 1992, Apr-29, Volume: 215, Issue:1

    Topics: Animals; Basilar Artery; Calcium; Cerebral Arteries; Cyclic AMP; Cyclic GMP; Dibenzoxazepines; Dogs; Endothelium, Vascular; In Vitro Techniques; Methylene Blue; Muscle Contraction; Muscle, Smooth, Vascular; Vasodilator Agents

1992
Modulation of the pharmacological actions of nitrovasodilators by methylene blue and pyocyanin.
    British journal of pharmacology, 1992, Volume: 106, Issue:4

    Topics: Animals; Aorta; Cyclic GMP; Drug Interactions; In Vitro Techniques; Methylene Blue; Molsidomine; Nitric Oxide; Nitroglycerin; Nitroprusside; Penicillamine; Platelet Aggregation; Pyocyanine; Rabbits; S-Nitroso-N-Acetylpenicillamine; Sodium Nitrite; Vasodilator Agents

1992
Key roles of nitric oxide and cyclic GMP in nonadrenergic and noncholinergic inhibition in rat ileum.
    European journal of pharmacology, 1992, Jun-05, Volume: 216, Issue:2

    Topics: Animals; Cyclic GMP; Dose-Response Relationship, Drug; Electric Stimulation; Ileum; Male; Methylene Blue; Muscle Contraction; Muscle, Smooth; Neural Inhibition; Nitric Oxide; Rats; Rats, Wistar

1992
Methylene blue inhibits nitrovasodilator- and endothelium-derived relaxing factor-induced cyclic GMP accumulation in cultured pulmonary arterial smooth muscle cells via generation of superoxide anion.
    The Journal of pharmacology and experimental therapeutics, 1992, Volume: 263, Issue:1

    Topics: Animals; Cattle; Cells, Cultured; Cyclic GMP; Free Radical Scavengers; Methylene Blue; Muscle, Smooth; Muscle, Smooth, Vascular; Nitric Oxide; Nitroso Compounds; Pulmonary Artery; Rabbits; Superoxide Dismutase

1992
The pharmacological activity of nitroxyl: a potent vasodilator with activity similar to nitric oxide and/or endothelium-derived relaxing factor.
    The Journal of pharmacology and experimental therapeutics, 1992, Volume: 263, Issue:2

    Topics: Animals; Aorta; Cattle; Cyanamide; Cyclic GMP; Endothelium, Vascular; Lung; Methylene Blue; Nitric Oxide; Nitrogen Oxides; Oxidation-Reduction; Rabbits; Vasodilator Agents

1992
Involvement of cyclic GMP in non-adrenergic, non-cholinergic inhibitory neurotransmission in dog proximal colon.
    British journal of pharmacology, 1992, Volume: 107, Issue:4

    Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Animals; Arginine; Autonomic Nervous System; Colon; Cyclic GMP; Dogs; Electric Stimulation; Female; Gastrointestinal Motility; Male; Methylene Blue; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; NG-Nitroarginine Methyl Ester; Nitric Oxide; Purinones; Signal Transduction; Synaptic Transmission

1992
Role of the L-arginine-NO pathway and of cyclic GMP in electrical field-induced noradrenaline release and vasoconstriction in the rat tail artery.
    British journal of pharmacology, 1992, Volume: 107, Issue:4

    Topics: Animals; Arginine; Arteries; Atrial Natriuretic Factor; Cyclic GMP; Electric Stimulation; Endothelium, Vascular; In Vitro Techniques; Male; Methylene Blue; Molsidomine; NG-Nitroarginine Methyl Ester; Nitric Oxide; Norepinephrine; Purinones; Rats; Tail; Vasoconstriction; Vasodilator Agents

1992
Role of nitric oxide and guanosine 3',5'-cyclic monophosphate in mediating nonadrenergic, noncholinergic relaxation in guinea-pig pulmonary arteries.
    British journal of pharmacology, 1992, Volume: 107, Issue:3

    Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Animals; Arginine; Autonomic Nervous System; Cyclic GMP; Electric Stimulation; Guinea Pigs; In Vitro Techniques; Male; Methylene Blue; Muscle Relaxation; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Norepinephrine; omega-N-Methylarginine; Oxidopamine; Phosphodiesterase Inhibitors; Purinones; Pyrogallol; Sympathectomy, Chemical

1992
Methylene blue inhibits hypoxic cerebral vasodilation in awake sheep.
    Journal of applied physiology (Bethesda, Md. : 1985), 1992, Volume: 73, Issue:6

    Topics: Animals; Blood Gas Analysis; Blood Pressure; Brain Chemistry; Cerebrovascular Circulation; Cyclic GMP; Female; Hydrogen-Ion Concentration; Hypoxia, Brain; Lactates; Methylene Blue; Microspheres; Nitric Oxide; Oxygen Consumption; Sheep; Vasodilation

1992
Possible mechanisms of age-associated reduction of vascular relaxation caused by atrial natriuretic peptide.
    European journal of pharmacology, 1992, Jan-07, Volume: 210, Issue:1

    Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Aging; Animals; Aorta, Thoracic; Arginine; Atrial Natriuretic Factor; Cyclic GMP; Endothelium, Vascular; Guanylate Cyclase; Hemoglobins; In Vitro Techniques; Male; Methylene Blue; Muscle Relaxation; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Purinones; Rats; Rats, Inbred Strains

1992
Guanylate cyclase inhibitors: effect on tone, relaxation, and cGMP content of lower esophageal sphincter.
    The American journal of physiology, 1992, Volume: 263, Issue:1 Pt 1

    Topics: Animals; Calcium; Cyclic GMP; Cystamine; Electric Stimulation; Esophagogastric Junction; Female; Guanylate Cyclase; Male; Membrane Potentials; Methylene Blue; Muscle Relaxation; Muscle Tonus; Opossums; Rest

1992
Retinal on-bipolar cells contain a nitric oxide-sensitive guanylate cyclase.
    Neuroreport, 1992, Volume: 3, Issue:10

    Topics: Animals; Antigens, Neoplasm; Calcium-Binding Proteins; Cyclic GMP; Dogfish; Eye Proteins; Ferricyanides; Guanylate Cyclase; Hippocalcin; In Vitro Techniques; Lipoproteins; Methylene Blue; Nerve Tissue Proteins; Nitric Oxide; Nitroprusside; Recoverin; Retina

1992
Involvement of nitric oxide pathway in the PAF-induced relaxation of rat thoracic aorta.
    British journal of pharmacology, 1992, Volume: 107, Issue:1

    Topics: Aging; Animals; Aorta, Thoracic; Arginine; Cyclic AMP; Cyclic GMP; Endothelium, Vascular; Guanylate Cyclase; Hemoglobins; Male; Methylene Blue; Muscle Relaxation; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Platelet Activating Factor; Pyridinium Compounds; Rats; Rats, Wistar

1992
The local intracoronary administration of methylene blue prevents the pronounced antiarrhythmic effect of ischaemic preconditioning.
    British journal of pharmacology, 1992, Volume: 107, Issue:4

    Topics: Animals; Arrhythmias, Cardiac; Coronary Vessels; Cyclic GMP; Dogs; Guanylate Cyclase; Infusions, Intra-Arterial; Methylene Blue; Myocardial Ischemia

1992
Induction of nitric oxide synthase by lipoteichoic acid from Staphylococcus aureus in vascular smooth muscle cells.
    FEBS letters, 1992, Feb-03, Volume: 297, Issue:1-2

    Topics: Amino Acid Oxidoreductases; Animals; Arginine; Cells, Cultured; Cyclic GMP; Enzyme Induction; Kinetics; Lipopolysaccharides; Methylene Blue; Muscle Contraction; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Phenylephrine; Rats; Staphylococcus aureus; Teichoic Acids

1992
Halothane-induced relaxation of vascular smooth muscle: a possible contribution of increased cyclic GMP formation.
    Japanese journal of pharmacology, 1991, Volume: 55, Issue:1

    Topics: Animals; Cyclic GMP; Dexamethasone; Halothane; In Vitro Techniques; Indomethacin; Male; Methylene Blue; Muscle, Smooth, Vascular; Rats; Rats, Inbred Strains; Vasodilator Agents

1991
Generation of an endothelium-derived relaxing factor-like substance in bovine tracheal smooth muscle.
    The American journal of physiology, 1991, Volume: 260, Issue:6 Pt 1

    Topics: Animals; Arginine; Atropine; Carbachol; Cattle; Cyclic GMP; Hemoglobins; In Vitro Techniques; Kinetics; Methylene Blue; Muscle, Smooth; Nitric Oxide; Pyrogallol; Superoxide Dismutase; Superoxides; Trachea

1991
L-arginine induces relaxation of rat aorta possibly through non-endothelial nitric oxide formation.
    British journal of pharmacology, 1991, Volume: 102, Issue:4

    Topics: Animals; Aorta, Thoracic; Arginine; Cyclic AMP; Cyclic GMP; Endothelium, Vascular; Hemoglobins; In Vitro Techniques; Male; Methylene Blue; Muscle Relaxation; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitroarginine; Rats; Rats, Inbred Strains

1991
Two mechanisms mediate relaxation by bradykinin of pig coronary artery: NO-dependent and -independent responses.
    The American journal of physiology, 1991, Volume: 261, Issue:3 Pt 2

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Arginine; Bradykinin; Coronary Vessels; Cyclic GMP; Dose-Response Relationship, Drug; In Vitro Techniques; Methylene Blue; Muscle, Smooth, Vascular; Nitric Oxide; omega-N-Methylarginine; Potassium; Prostaglandin Endoperoxides, Synthetic; Swine; Vasodilation

1991
The calcium channel antagonist S 11568 causes endothelium-dependent relaxation in canine arteries.
    European journal of pharmacology, 1991, May-02, Volume: 197, Issue:1

    Topics: Animals; Arginine; Calcium Channel Blockers; Cyclic GMP; Dihydropyridines; Dogs; Endothelium, Vascular; Female; Hemoglobins; In Vitro Techniques; Male; Methylene Blue; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; omega-N-Methylarginine

1991
Effects of the mammalian lignan, 2,3-dibenzyl-butane-1,4-diol, on contraction and Ca2+ mobilization induced by noradrenaline in rat aorta.
    General pharmacology, 1991, Volume: 22, Issue:4

    Topics: Animals; Aorta, Thoracic; Benzyl Compounds; Calcium; Cyclic GMP; In Vitro Techniques; Male; Methylene Blue; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Rats; Rats, Inbred Strains

1991
In vivo attenuation of endothelium-dependent pulmonary vasodilation by methylene blue.
    Journal of applied physiology (Bethesda, Md. : 1985), 1991, Volume: 71, Issue:2

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acetylcholine; Animals; Animals, Newborn; Blood Pressure; Cyclic GMP; Endothelium, Vascular; Heart Rate; Hemodynamics; Infusions, Intravenous; Methylene Blue; Muscle Tonus; Muscle, Smooth, Vascular; Prostaglandin Endoperoxides, Synthetic; Pulmonary Circulation; Sheep; Vasodilation; Vasodilator Agents

1991
2-Nicotinamidoethyl acetate (SG-209) is a potassium channel opener: structure activity relationship among nicorandil derivatives.
    Naunyn-Schmiedeberg's archives of pharmacology, 1991, Volume: 344, Issue:2

    Topics: Animals; Cyclic GMP; Glyburide; Male; Methylene Blue; Niacinamide; Nicorandil; Phenylephrine; Potassium Channels; Rabbits; Structure-Activity Relationship; Vasodilation; Vasodilator Agents

1991
Hypoxic contraction of canine coronary arteries: role of endothelium and cGMP.
    The American journal of physiology, 1991, Volume: 261, Issue:6 Pt 2

    Topics: Animals; Arginine; Coronary Vessels; Cyclic GMP; Dinoprost; Dogs; Endothelium, Vascular; Female; Hypoxia; In Vitro Techniques; Male; Methylene Blue; Muscle Contraction; Muscle, Smooth, Vascular; Nitric Oxide; Nitroarginine; Oxygen

1991
Platelet inhibition by an L-arginine-derived substance released by IL-1 beta-treated vascular smooth muscle cells.
    The American journal of physiology, 1991, Volume: 261, Issue:6 Pt 2

    Topics: Animals; Aorta, Thoracic; Arginine; Blood Platelets; Cells, Cultured; Cyclic GMP; Drug Synergism; Interleukin-1; Methylene Blue; Muscle, Smooth, Vascular; Nitric Oxide; Nitroarginine; Platelet Aggregation; Platelet Aggregation Inhibitors; Rats; Superoxide Dismutase; Thrombin

1991
The molecular mechanism of action of peripheral morphine analgesia: stimulation of the cGMP system via nitric oxide release.
    European journal of pharmacology, 1991, Aug-16, Volume: 201, Issue:1

    Topics: Analgesia; Animals; Arginine; Cyclic GMP; Male; Methylene Blue; Molsidomine; Morphine; Nitric Oxide; Ornithine; Phthalazines; Rats; Rats, Inbred Strains

1991
The effect of inhibitors of nitric oxide biosynthesis and cyclic GMP formation on nerve-evoked relaxation of human cavernosal smooth muscle.
    British journal of pharmacology, 1991, Volume: 104, Issue:3

    Topics: Arginine; Autonomic Nervous System; Cyclic GMP; Electric Stimulation; Guanethidine; Humans; In Vitro Techniques; Male; Methylene Blue; Muscle Relaxation; Muscle, Smooth; Nitric Oxide; Nitroarginine; Penis; Synaptic Transmission

1991
Calcitonin gene-related peptide (CGRP)-induced cyclic AMP, cyclic GMP and vasorelaxant responses in rat thoracic aorta are antagonized by blockers of endothelium-derived relaxant factor (EDRF).
    Neuropeptides, 1991, Volume: 20, Issue:2

    Topics: Acetylcholine; Animals; Aorta, Thoracic; Calcitonin Gene-Related Peptide; Cyclic AMP; Cyclic GMP; Endothelium, Vascular; Hemoglobins; Indomethacin; Male; Masoprocol; Methylene Blue; Muscle Relaxation; Nitric Oxide; Norepinephrine; Rats; Rats, Inbred Strains; Vasodilation

1991
Stimulative effect of sodium nitroprusside on peristaltic reflex in isolated guinea pig ileal segments.
    Japanese journal of pharmacology, 1991, Volume: 57, Issue:3

    Topics: Animals; Arginine; Cyclic GMP; Electric Stimulation; Guinea Pigs; Ileum; In Vitro Techniques; Methylene Blue; Muscle Contraction; Neurons; Nitric Oxide; Nitroarginine; Nitroglycerin; Nitroprusside; Peristalsis; Stimulation, Chemical

1991
Interleukin 1 induces prolonged L-arginine-dependent cyclic guanosine monophosphate and nitrite production in rat vascular smooth muscle cells.
    The Journal of clinical investigation, 1991, Volume: 87, Issue:2

    Topics: Aminoquinolines; Animals; Arginine; Cells, Cultured; Cyclic GMP; Enzyme Activation; Guanylate Cyclase; Hemoglobins; Interleukin-1; Methylene Blue; Muscle, Smooth, Vascular; Nitrites; omega-N-Methylarginine; Protein Synthesis Inhibitors; Rats

1991
Relationship between cyclic guanosine monophosphate accumulation and relaxation of canine trachealis induced by nitrovasodilators.
    The Journal of pharmacology and experimental therapeutics, 1991, Volume: 258, Issue:3

    Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Animals; Cyclic GMP; Dogs; Drug Synergism; Female; Guanylate Cyclase; Hemoglobins; Isoproterenol; Male; Methylene Blue; Muscle Relaxation; Nitroglycerin; Nitroprusside; Penicillamine; Purinones; S-Nitroso-N-Acetylpenicillamine; Time Factors; Trachea; Vasodilator Agents

1991
L-arginine stimulates cyclic guanosine 3',5'-monophosphate formation in rat islets of Langerhans and RINm5F insulinoma cells: evidence for L-arginine:nitric oxide synthase.
    Endocrinology, 1991, Volume: 129, Issue:6

    Topics: Aminoquinolines; Animals; Arginine; Cyclic GMP; Glucose; Guanylate Cyclase; Insulin; Insulin Secretion; Insulinoma; Islets of Langerhans; Male; Methylene Blue; Nitroprusside; Pancreatic Neoplasms; Rats; Rats, Inbred Strains; Tumor Cells, Cultured

1991
Interleukin 1 and endotoxin activate soluble guanylate cyclase in vascular smooth muscle.
    The American journal of physiology, 1990, Volume: 259, Issue:1 Pt 2

    Topics: 1-Methyl-3-isobutylxanthine; Aminoquinolines; Animals; Aorta; Cyclic GMP; Endothelium, Vascular; Endotoxins; Enzyme Activation; Guanylate Cyclase; Interleukin-1; Male; Methylene Blue; Muscle, Smooth, Vascular; Myocardial Contraction; Rats; Rats, Inbred Strains; SRS-A; Time Factors; Vasodilation

1990
Differences in vascular responses to vasoactive agents of basilar artery and aorta from rabbits with alloxan-induced diabetes.
    Canadian journal of physiology and pharmacology, 1990, Volume: 68, Issue:7

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Aorta, Thoracic; Basilar Artery; Blood Glucose; Cyclic AMP; Cyclic GMP; Diabetes Mellitus, Experimental; Endothelium, Vascular; Male; Methylene Blue; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Potassium Chloride; Propranolol; Rabbits; Serotonin

1990
Cyclic GMP mediates SIN-1-induced inhibition of human polymorphonuclear leukocytes.
    European journal of pharmacology, 1990, Jul-03, Volume: 182, Issue:2

    Topics: 1-Methyl-3-isobutylxanthine; Cyanides; Cyclic AMP; Cyclic GMP; Glucuronidase; Humans; In Vitro Techniques; Macrophage Activation; Methylene Blue; Molsidomine; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Nitroglycerin; Nitroprusside; Nitrosamines; Vasodilator Agents

1990
Activation of membrane guanylate cyclase by an invertebrate peptide hormone.
    The Journal of biological chemistry, 1990, Nov-25, Volume: 265, Issue:33

    Topics: 1-Methyl-3-isobutylxanthine; Animals; Aorta; Arthropod Proteins; Cell Membrane; Cells, Cultured; Cyclic GMP; Enzyme Activation; Ganglia, Spinal; Guanylate Cyclase; Invertebrate Hormones; Kinetics; Male; Methylene Blue; Muscle, Smooth, Vascular; Muscles; Nephropidae; Nerve Tissue Proteins; Neurons; Nitroprusside; Rats; Rats, Inbred Strains

1990
Characteristics of the vasorelaxing action of (3E)-4-ethyl-2-hydroximino-5-nitro-3-hexamide FK409, a new vasodilator isolated from microbial sources, in isolated rabbit arteries.
    Journal of cardiovascular pharmacology, 1991, Volume: 17, Issue:3

    Topics: Animals; Arteries; Caffeine; Calcium; Cyclic GMP; Hemoglobins; Histamine; In Vitro Techniques; Inositol Phosphates; Male; Methylene Blue; Nitro Compounds; Nitroglycerin; Norepinephrine; Purinones; Rabbits; Serotonin; Vasoconstriction; Vasodilator Agents

1991
Dual mechanism of the relaxing effect of nicorandil by stimulation of cyclic GMP formation and by hyperpolarization.
    Journal of cardiovascular pharmacology, 1991, Volume: 17, Issue:4

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Barium; Cattle; Coronary Vessels; Cyclic GMP; Enzyme Activation; Guanylate Cyclase; In Vitro Techniques; Methylene Blue; Muscle Relaxation; Muscle, Smooth, Vascular; Neuromuscular Junction; Niacinamide; Nicorandil; Nitroprusside; Potassium; Potassium Channels; Prostaglandin Endoperoxides, Synthetic; Vasodilator Agents

1991
Nicorandil-induced vasorelaxation: functional evidence for K+ channel-dependent and cyclic GMP-dependent components in a single vascular preparation.
    Journal of cardiovascular pharmacology, 1991, Volume: 17, Issue:6

    Topics: Animals; Calcium; Cyclic GMP; Drug Tolerance; Mesenteric Arteries; Methylene Blue; Muscle Contraction; Muscle, Smooth, Vascular; Niacinamide; Nicorandil; Nitroglycerin; Norepinephrine; Potassium; Potassium Channels; Rabbits; Vasodilator Agents

1991
Differential inhibition and potentiation by cell-permeant analogues of cyclic AMP and cyclic GMP and NO-containing compounds of exocytosis in human neutrophils.
    Naunyn-Schmiedeberg's archives of pharmacology, 1991, Volume: 344, Issue:4

    Topics: 1-Methyl-3-isobutylxanthine; Calcium; Cell Aggregation; Complement C5a; Cyanides; Cyclic AMP; Cyclic GMP; Exocytosis; Glucuronidase; Humans; In Vitro Techniques; Methylene Blue; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Nitroprusside; Nitrous Oxide; Superoxide Dismutase

1991
Endothelin and a Ca2+ ionophore raise cyclic GMP levels in a neuronal cell line via formation of nitric oxide.
    British journal of pharmacology, 1990, Volume: 101, Issue:3

    Topics: Animals; Calcium; Cell Line; Cyclic GMP; Endothelins; Hybrid Cells; Ionomycin; Methylene Blue; Neurons; Nitric Oxide; Veratridine

1990
Study on the mechanism of carbon monoxide induced endothelium-independent relaxation in porcine coronary artery and vein.
    Biomedica biochimica acta, 1990, Volume: 49, Issue:4

    Topics: Animals; Carbon Monoxide; Coronary Vessels; Cyclic GMP; Dinoprost; Enzyme Activation; Guanylate Cyclase; Methylene Blue; Muscle Relaxation; Muscle, Smooth, Vascular; Signal Transduction; Swine

1990
Vascular smooth muscle relaxation by endothelium-dependent beta 1-adrenergic action.
    Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology, 1990, Volume: 97, Issue:2

    Topics: Animals; Aorta; Cyclic GMP; Endothelium, Vascular; Indomethacin; Male; Methylene Blue; Metoprolol; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; Norepinephrine; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; Yohimbine

1990
Potentiation of nonadrenergic neural relaxation in guinea pig airways by a cyclic cAMP phosphodiesterase inhibitor.
    The Journal of pharmacology and experimental therapeutics, 1990, Volume: 252, Issue:1

    Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Cyclic GMP; Dose-Response Relationship, Drug; Electric Stimulation; Ethylmaleimide; Guinea Pigs; In Vitro Techniques; Male; Methylene Blue; Muscle Contraction; Muscle Relaxation; Nitroprusside; Potassium Chloride; Pyrazines; Tetrodotoxin; Trachea; Vasoactive Intestinal Peptide

1990
Comparison of the hemodynamic effects of nitric oxide and endothelium-dependent vasodilators in intact lungs.
    Journal of applied physiology (Bethesda, Md. : 1985), 1990, Volume: 68, Issue:2

    Topics: Acetylcholine; Animals; Bradykinin; Cyclic GMP; Endothelium, Vascular; Hemodynamics; Hypertension, Pulmonary; Hypoxia; Lung; Male; Methylene Blue; Monocrotaline; Nitric Oxide; Pulmonary Circulation; Pyrrolizidine Alkaloids; Rats; Rats, Inbred Strains; Vasodilation

1990
Inotropic, electrophysiological and biochemical responses to histamine in rabbit papillary muscles: evidence for coexistence of H1- and H2-receptors.
    The Journal of pharmacology and experimental therapeutics, 1990, Volume: 253, Issue:1

    Topics: Action Potentials; Animals; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Female; Histamine; In Vitro Techniques; Male; Methylene Blue; Myocardial Contraction; Nitroprusside; Papillary Muscles; Phosphatidylinositols; Rabbits; Receptors, Histamine H2

1990
Effects of hypoxia on endothelium-dependent relaxation of rat pulmonary artery.
    The American journal of physiology, 1990, Volume: 258, Issue:4 Pt 1

    Topics: Acetylcholine; Adenosine Monophosphate; Animals; Cyclic AMP; Cyclic GMP; Dideoxyadenosine; Endothelium, Vascular; Hemoglobins; Hypoxia; In Vitro Techniques; Isomerism; Kinetics; Male; Methylene Blue; Muscle, Smooth, Vascular; Nitric Oxide; Phenylephrine; Pulmonary Artery; Rats; Rats, Inbred Strains; Thionucleotides; Vasodilation

1990
Developmental changes in sodium nitroprusside and atrial natriuretic factor mediated relaxation in the guinea pig aorta.
    Pediatric research, 1990, Volume: 27, Issue:4 Pt 1

    Topics: Aging; Animals; Animals, Newborn; Aorta, Thoracic; Atrial Natriuretic Factor; Cyclic GMP; Female; Ferricyanides; Fetus; Guinea Pigs; In Vitro Techniques; Male; Methylene Blue; Nitroprusside; Vasodilation

1990
Neutrophil-derived relaxing factor relaxes vascular smooth muscle through a cGMP-mediated mechanism.
    Life sciences, 1990, Volume: 46, Issue:21

    Topics: Animals; Cyclic AMP; Cyclic GMP; Endothelium, Vascular; In Vitro Techniques; Male; Methylene Blue; Muscle, Smooth, Vascular; Myocardial Contraction; Neutrophils; Nitric Oxide; Peritoneal Cavity; Phenylephrine; Purinones; Rats; Rats, Inbred Lew; Superoxide Dismutase

1990
Self suppression of phosphoinositide turnover and contraction by stimulating release of endogenous endothelium derived relaxing factor in vascular action of histamine.
    Cardiovascular research, 1990, Volume: 24, Issue:5

    Topics: Animals; Calcimycin; Calcium; Cimetidine; Cyclic GMP; Diphenhydramine; Endothelium, Vascular; Histamine; In Vitro Techniques; Methylene Blue; Muscle Contraction; Muscle, Smooth, Vascular; Nitric Oxide; Phosphatidylinositols; Rabbits

1990
Effects of methylene blue on hypoxic cerebral vasodilatation in the rabbit.
    The Journal of pharmacology and experimental therapeutics, 1990, Volume: 254, Issue:2

    Topics: Animals; Cerebrovascular Circulation; Cyclic GMP; Drug Interactions; Hypoxia; Injections, Intravenous; Male; Methylene Blue; Muscle, Smooth, Vascular; Nitroglycerin; Papaverine; Rabbits; Vasodilation

1990
EDRF-release and Ca+(+)-channel blockade by magnolol, an antiplatelet agent isolated from Chinese herb Magnolia officinalis, in rat thoracic aorta.
    Life sciences, 1990, Volume: 47, Issue:13

    Topics: Animals; Aorta; Biphenyl Compounds; Calcium; Calcium Channels; Cyclic GMP; Drugs, Chinese Herbal; Endothelium, Vascular; Epoprostenol; Female; Hemoglobins; In Vitro Techniques; Lignans; Male; Methylene Blue; Nitric Oxide; Norepinephrine; Platelet Aggregation Inhibitors; Rats; Rats, Inbred Strains; Vasoconstriction

1990
Stimulation of cyclic GMP production in cultured endothelial cells of the pig by bradykinin, adenosine diphosphate, calcium ionophore A23187 and nitric oxide.
    British journal of pharmacology, 1990, Volume: 101, Issue:1

    Topics: Adenosine Diphosphate; Animals; Arginine; Bradykinin; Calcimycin; Cells, Cultured; Cyclic AMP; Cyclic GMP; Endothelium, Vascular; In Vitro Techniques; Kinetics; Methylene Blue; Nitric Oxide; omega-N-Methylarginine; Oxyhemoglobins; Stimulation, Chemical; Superoxide Dismutase; Superoxides; Swine

1990
Coronary vascular actions of synthetic atrial natriuretic factor in isolated vascular preparations.
    Journal of cardiovascular pharmacology, 1987, Volume: 10, Issue:3

    Topics: Animals; Atrial Natriuretic Factor; Cats; Coronary Vessels; Cyclic GMP; Endothelium, Vascular; In Vitro Techniques; Male; Methylene Blue; Papillary Muscles; Vasodilation

1987
Methylene blue selectively inhibits pulmonary vasodilator responses in cats.
    Journal of applied physiology (Bethesda, Md. : 1985), 1989, Volume: 66, Issue:3

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Acetylcholine; Angiotensin II; Animals; Blood Pressure; Bradykinin; Cats; Cyclic GMP; Epinephrine; Female; Isoproterenol; Male; Methylene Blue; Nitroglycerin; Prostaglandin Endoperoxides, Synthetic; Pulmonary Artery; Pulmonary Circulation; Reference Values; Vasodilation

1989
Role of selective cyclic GMP phosphodiesterase inhibition in the myorelaxant actions of M&B 22,948, MY-5445, vinpocetine and 1-methyl-3-isobutyl-8-(methylamino)xanthine.
    British journal of pharmacology, 1989, Volume: 98, Issue:3

    Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-GMP Phosphodiesterases; Animals; Aorta, Thoracic; Cyclic AMP; Cyclic GMP; In Vitro Techniques; Kinetics; Male; Methylene Blue; Muscle Relaxants, Central; Nitric Oxide; Phthalazines; Purinones; Pyridazines; Rats; Rats, Inbred Strains; Theophylline; Vinca Alkaloids

1989
SIN-1 stimulates the production of cyclic GMP but not cyclic AMP in porcine aortic endothelial cells.
    Journal of cardiovascular pharmacology, 1989, Volume: 14 Suppl 11

    Topics: Animals; Aorta, Thoracic; Cells, Cultured; Cyclic AMP; Cyclic GMP; Endothelium, Vascular; Heme; Methylene Blue; Molsidomine; Rodentia; Vasodilator Agents

1989
H2O2 and cGMP may function as an O2 sensor in the pulmonary artery.
    Journal of applied physiology (Bethesda, Md. : 1985), 1989, Volume: 66, Issue:1

    Topics: Animals; Catalase; Cattle; Cyclic GMP; Enzyme Activation; Hydrogen Peroxide; In Vitro Techniques; Methylene Blue; Oxygen; Pulmonary Artery; Vasoconstriction

1989
Influence of stimulators and inhibitors of cyclic nucleotides on lower esophageal sphincter.
    The Journal of pharmacology and experimental therapeutics, 1989, Volume: 248, Issue:2

    Topics: Animals; Colforsin; Cyclic AMP; Cyclic GMP; Electric Stimulation; Esophagogastric Junction; Ethylmaleimide; Female; In Vitro Techniques; Male; Methylene Blue; Muscle Contraction; Nitroprusside; Opossums; Phosphodiesterase Inhibitors; Vasoactive Intestinal Peptide

1989
Methylene blue but not changes in cyclic GMP inhibits resting and bradykinin-stimulated production of prostacyclin by pig aortic endothelial cells.
    British journal of pharmacology, 1989, Volume: 97, Issue:1

    Topics: 6-Ketoprostaglandin F1 alpha; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Aorta; Atrial Natriuretic Factor; Bradykinin; Cyclic GMP; Endothelium, Vascular; Epoprostenol; Hemoglobins; In Vitro Techniques; Methylene Blue; Swine

1989
Cyclic GMP: a potential mediator of neurally- and drug-induced relaxation of opossum lower esophageal sphincter.
    The Journal of pharmacology and experimental therapeutics, 1989, Volume: 249, Issue:2

    Topics: Animals; Cyclic GMP; Electric Stimulation; Esophagogastric Junction; Female; Male; Methylene Blue; Muscle Relaxation; Nitroprusside; Opossums; Purinones

1989
Atrial natriuretic peptide and nitroprusside cause relaxation of cultured rat mesangial cells.
    The American journal of physiology, 1989, Volume: 257, Issue:1 Pt 1

    Topics: Amanitins; Angiotensin II; Animals; Atrial Natriuretic Factor; Cells, Cultured; Cyclic GMP; Dibutyryl Cyclic GMP; Ferricyanides; Fluorescent Dyes; Glomerular Mesangium; Methylene Blue; Microscopy, Fluorescence; Nitroprusside; Rats

1989
Stimulation of glucose transport in rat cardiac myocytes by guanosine 3',5'-monophosphate.
    Endocrinology, 1989, Volume: 125, Issue:2

    Topics: Aminophylline; Animals; Cyclic AMP; Cyclic CMP; Cyclic GMP; Cyclic IMP; Dose-Response Relationship, Drug; Estradiol; Female; Glucose; Insulin; Methylene Blue; Myocardium; Nucleotides, Cyclic; Phosphodiesterase Inhibitors; Rats; Rats, Inbred Strains; Uridine Monophosphate

1989
Human endothelial cells inhibit platelet aggregation by separately stimulating platelet cyclic AMP and cyclic GMP.
    European journal of pharmacology, 1989, May-02, Volume: 164, Issue:1

    Topics: Biological Factors; Blood Platelets; Cyclic AMP; Cyclic GMP; Endothelium, Vascular; Epoprostenol; Gossypol; Hemoglobins; Humans; In Vitro Techniques; Indomethacin; Male; Methylene Blue; Nitric Oxide; Platelet Aggregation

1989
Effect of endothelium on basal and on stimulated accumulation and efflux of cyclic GMP in rat isolated aorta.
    British journal of pharmacology, 1989, Volume: 97, Issue:3

    Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Acetylcholine; Animals; Aorta, Thoracic; Atrial Natriuretic Factor; Biological Factors; Calcium; Carbachol; Cyclic GMP; Endothelium, Vascular; Histamine; Male; Methylene Blue; Muscle, Smooth, Vascular; Nitric Oxide; Nitroprusside; Rats; Rats, Inbred Strains; Vasodilator Agents

1989
Effects of hydralazine on guanosine cyclic 3', 5'-monophosphate levels in rat aorta.
    Proceedings of the National Science Council, Republic of China. Part B, Life sciences, 1989, Volume: 13, Issue:2

    Topics: Animals; Aorta; Biological Transport; Calcium; Cyclic GMP; Endothelium, Vascular; Female; Guanylate Cyclase; Hydralazine; Male; Methylene Blue; Norepinephrine; Potassium; Rats; Rats, Inbred Strains; Vasodilation

1989
In vitro vascular relaxation by new inotropic agents: relationship to phosphodiesterase inhibition and cyclic nucleotides.
    The Journal of pharmacology and experimental therapeutics, 1987, Volume: 242, Issue:3

    Topics: 2',3'-Cyclic-Nucleotide Phosphodiesterases; Animals; Aorta; Cardiotonic Agents; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Endothelium, Vascular; In Vitro Techniques; Male; Methylene Blue; Rats; Rats, Inbred Strains; Vasodilation

1987
Mechanisms of endothelium-dependent vascular smooth muscle relaxation elicited by bradykinin and VIP.
    The American journal of physiology, 1987, Volume: 253, Issue:5 Pt 2

    Topics: Animals; Bradykinin; Cattle; Cyclic AMP; Cyclic GMP; Endothelium, Vascular; Indomethacin; Methylene Blue; Muscle Contraction; Muscle Relaxation; Potassium; Vasoactive Intestinal Peptide; Vasodilation

1987
In vivo effect of methylene blue on endothelium-dependent and endothelium-independent dilations of brain microvessels in mice.
    Circulation research, 1988, Volume: 62, Issue:1

    Topics: Acetylcholine; Animals; Bradykinin; Cerebrovascular Circulation; Cyclic GMP; Endothelium, Vascular; Male; Methylene Blue; Mice; Nitroprusside; Vasodilation

1988
Methylene blue enhances hypoxic contraction in isolated rat pulmonary arteries.
    Chest, 1988, Volume: 93, Issue:3 Suppl

    Topics: Animals; Biological Products; Cyclic GMP; Hypoxia; In Vitro Techniques; Methylene Blue; Nitric Oxide; Pulmonary Artery; Rats; Vasoconstriction

1988
Enhanced vascular effects of cyclic GMP in septic rat aorta.
    The American journal of physiology, 1988, Volume: 254, Issue:3 Pt 2

    Topics: Animals; Aorta; Bacterial Infections; Biological Products; Cyclic GMP; In Vitro Techniques; Male; Methylene Blue; Myoglobin; Nitric Oxide; Norepinephrine; Potassium Chloride; Rats; Rats, Inbred Strains; Vasoconstriction

1988
Relationship between LTD4-induced endothelium-dependent vasomotor relaxation and cGMP.
    The Journal of pharmacology and experimental therapeutics, 1988, Volume: 245, Issue:1

    Topics: Acetylcholine; Animals; Cyclic GMP; Dogs; Endothelium, Vascular; Isoproterenol; Mesenteric Arteries; Methylene Blue; Nitroglycerin; Norepinephrine; SRS-A; Vasodilation; Vasomotor System

1988
Atrial natriuretic factor-responding and cyclic guanosine monophosphate (cGMP)-producing cells in the rat hippocampus: a combined micropharmacological and immunocytochemical approach.
    Brain research, 1988, Apr-19, Volume: 446, Issue:2

    Topics: Animals; Antibodies; Atrial Natriuretic Factor; Cyclic GMP; Hippocampus; Immunohistochemistry; Kinetics; Male; Methylene Blue; Nitroprusside; Rats; Rats, Inbred Strains

1988
Interaction of atriopeptin III and vasopressin on calcium kinetics and contraction of aortic smooth muscle cells.
    The Journal of clinical investigation, 1988, Volume: 82, Issue:4

    Topics: Animals; Aorta, Thoracic; Arginine Vasopressin; Atrial Natriuretic Factor; Calcium; Calcium Channels; Calcium Radioisotopes; Cyclic GMP; Drug Interactions; Inositol Phosphates; Intracellular Fluid; Kinetics; Male; Methylene Blue; Muscle Contraction; Muscle, Smooth, Vascular; Nucleotides, Cyclic; Rats; Rats, Inbred Strains

1988
Independent blockade of cerebral vasodilation from acetylcholine and nitric oxide.
    The American journal of physiology, 1988, Volume: 255, Issue:4 Pt 2

    Topics: Acetylcholine; Animals; Arterioles; Catalase; Cats; Cerebrovascular Circulation; Cyclic GMP; Deferoxamine; Methylene Blue; Nitric Oxide; Nitroblue Tetrazolium; Reference Values; Superoxide Dismutase; Vasodilation

1988
Acetylcholine releases endothelium-derived hyperpolarizing factor and EDRF from rat blood vessels.
    British journal of pharmacology, 1988, Volume: 95, Issue:4

    Topics: Acetylcholine; Animals; Aorta, Thoracic; Biological Factors; Cyclic GMP; Endothelium, Vascular; Female; Hemoglobins; In Vitro Techniques; Male; Membrane Potentials; Methylene Blue; Nitric Oxide; Potassium Channels; Pulmonary Artery; Rats; Vasoconstriction

1988
Stimulation of soluble coronary arterial guanylate cyclase by SIN-1.
    European journal of pharmacology, 1986, Mar-11, Volume: 122, Issue:1

    Topics: Animals; Cations, Divalent; Cattle; Coronary Vessels; Cyclic GMP; Ferricyanides; Guanylate Cyclase; In Vitro Techniques; Methylene Blue; Molsidomine; Muscle Relaxation; Muscle, Smooth, Vascular; Nitroglycerin; Nitroprusside; Oxadiazoles; Sodium Nitrite; Sulfhydryl Compounds; Sydnones

1986
Hydrogen peroxide elicits pulmonary arterial relaxation and guanylate cyclase activation.
    The American journal of physiology, 1987, Volume: 252, Issue:4 Pt 2

    Topics: Acetylcholine; Animals; Catalase; Cattle; Cyclic GMP; Endothelium; Enzyme Activation; Glucose Oxidase; Guanylate Cyclase; Histamine; Hydrogen Peroxide; In Vitro Techniques; Indomethacin; Methylene Blue; Pulmonary Artery; Pulmonary Circulation; Serotonin; Superoxide Dismutase; Vasomotor System

1987
Atrial natriuretic peptide, oxytocin, and vasopressin increase guanosine 3',5'-monophosphate in LLC-PK1 kidney epithelial cells.
    Endocrinology, 1988, Volume: 122, Issue:4

    Topics: Animals; Atrial Natriuretic Factor; Cells, Cultured; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Enzyme Activation; Epithelium; Guanylate Cyclase; Kidney; Methylene Blue; Oxytocin; Time Factors; Vasopressins

1988
Endothelium-derived relaxing factor and atriopeptin II elevate cyclic GMP levels in pig aortic endothelial cells.
    British journal of pharmacology, 1988, Volume: 93, Issue:1

    Topics: Adenylyl Cyclases; Animals; Atrial Natriuretic Factor; Biological Products; Catalase; Cyclic AMP; Cyclic GMP; Endothelium, Vascular; Epoprostenol; Guanylate Cyclase; Hemoglobins; In Vitro Techniques; Methylene Blue; Nitric Oxide; Superoxide Dismutase; Swine

1988
Guanosine 3',5'-cyclic monophosphate as a mediator of inhibition of renin release.
    The American journal of physiology, 1988, Volume: 255, Issue:3 Pt 2

    Topics: Animals; Arachidonic Acid; Arachidonic Acids; Atrial Natriuretic Factor; Cyclic GMP; Guanylate Cyclase; In Vitro Techniques; Isoproterenol; Kidney Cortex; Kinetics; Methylene Blue; Nitroprusside; Rats; Renin

1988
Cyclic GMP and cell death in rat cerebellar slices.
    Neuroscience, 1988, Volume: 26, Issue:1

    Topics: Animals; Cell Survival; Cerebellum; Cyclic GMP; Enzyme Inhibitors; Ethacrynic Acid; Free Radicals; Guanylate Cyclase; Hydroxylamines; In Vitro Techniques; Methylene Blue; Neurotoxins; Nitroprusside; Rats

1988
Selective blockade of endothelium-dependent and glyceryl trinitrate-induced relaxation by hemoglobin and by methylene blue in the rabbit aorta.
    The Journal of pharmacology and experimental therapeutics, 1985, Volume: 232, Issue:3

    Topics: Acetylcholine; Animals; Aorta; Blood Vessels; Calcimycin; Cyclic AMP; Cyclic GMP; Drug Interactions; Endothelium; Hemoglobins; In Vitro Techniques; Isoproterenol; Male; Methylene Blue; Nitroglycerin; Rabbits; Vasodilation

1985
Effects of nitroprusside, glyceryl trinitrate, and 8-bromo cyclic GMP on phosphorylase a formation and myosin light chain phosphorylation in rat aorta.
    Molecular pharmacology, 1985, Volume: 27, Issue:3

    Topics: Animals; Cyclic GMP; Ferricyanides; Methylene Blue; Muscle, Smooth, Vascular; Myosins; Nitroglycerin; Nitroprusside; Norepinephrine; Phosphorylase a; Phosphorylases; Phosphorylation; Potassium Chloride; Rats

1985
Mechanisms of nitrate-induced vasodilatation and tolerance on a biochemical base.
    Zeitschrift fur Kardiologie, 1985, Volume: 74 Suppl 1

    Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Animals; Blood Pressure; Cattle; Coronary Circulation; Coronary Vessels; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Drug Tolerance; Isosorbide Dinitrate; Methylene Blue; Nitrates; Nitroglycerin; Nitroprusside; Vasodilation

1985
Differences in responsiveness of intrapulmonary artery and vein to arachidonic acid: mechanism of arterial relaxation involves cyclic guanosine 3':5'-monophosphate and cyclic adenosine 3':5'-monophosphate.
    The Journal of pharmacology and experimental therapeutics, 1985, Volume: 233, Issue:3

    Topics: Acetylcholine; Animals; Arachidonic Acid; Arachidonic Acids; Carbon Radioisotopes; Cattle; Cyclic AMP; Cyclic GMP; Endothelium; In Vitro Techniques; Methylene Blue; Muscle, Smooth, Vascular; Proadifen; Prostaglandins; Pulmonary Artery; Pulmonary Veins; Vasodilation

1985
Evidence that cyclic guanosine monophosphate (cGMP) mediates endothelium-dependent relaxation.
    European journal of pharmacology, 1985, Jun-07, Volume: 112, Issue:2

    Topics: Animals; Aorta, Thoracic; Blood Vessels; Cyclic GMP; Endothelium; In Vitro Techniques; Methylene Blue; Purinones; Rabbits; Vasodilation

1985
Effects of atrial natriuretic factor, sodium nitroprusside, and acetylcholine on cyclic GMP levels and relaxation in rat aorta.
    European journal of pharmacology, 1985, Sep-24, Volume: 115, Issue:2-3

    Topics: Acetylcholine; Animals; Aorta, Thoracic; Atrial Natriuretic Factor; Colforsin; Cyanides; Cyclic GMP; Ferricyanides; In Vitro Techniques; Male; Methylene Blue; Muscle Relaxation; Muscle, Smooth, Vascular; Nitroprusside; Norepinephrine; Potassium Chloride; Rats; Sodium-Potassium-Exchanging ATPase

1985
Dissimilarities between methylene blue and cyanide on relaxation and cyclic GMP formation in endothelium-intact intrapulmonary artery caused by nitrogen oxide-containing vasodilators and acetylcholine.
    The Journal of pharmacology and experimental therapeutics, 1986, Volume: 236, Issue:1

    Topics: Acetylcholine; Animals; Cattle; Cyanides; Cyclic GMP; Endothelium; In Vitro Techniques; Methylene Blue; Nitrogen Oxides; Nitroprusside; Pulmonary Artery; Vasodilation; Vasodilator Agents

1986
Isosorbide 5-mononitrate effects on isolated rabbit aorta and vena cava: relationship between cyclic GMP and relaxation of vascular smooth muscle.
    European journal of pharmacology, 1985, Nov-26, Volume: 118, Issue:1-2

    Topics: Animals; Aorta, Thoracic; Cyclic GMP; Female; In Vitro Techniques; Isosorbide Dinitrate; Male; Methylene Blue; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Norepinephrine; Rabbits; Vena Cava, Inferior

1985
Cyclic GMP as the mediator of molsidomine-induced vasodilatation.
    European journal of pharmacology, 1986, Mar-11, Volume: 122, Issue:1

    Topics: Animals; Cattle; Coronary Vessels; Cyclic GMP; Dose-Response Relationship, Drug; Drug Synergism; Drug Tolerance; Endothelium; In Vitro Techniques; Methylene Blue; Molsidomine; Muscle Relaxation; Muscle, Smooth, Vascular; Oxadiazoles; Phosphodiesterase Inhibitors; Sydnones; Time Factors; Vasodilation

1986
Methylene blue and ETYA block flow-dependent dilation in canine femoral artery.
    The American journal of physiology, 1986, Volume: 250, Issue:6 Pt 2

    Topics: 5,8,11,14-Eicosatetraynoic Acid; Acetylcholine; Animals; Arachidonic Acid; Arachidonic Acids; Cyclic GMP; Dogs; Dose-Response Relationship, Drug; Fatty Acids, Unsaturated; Female; Femoral Artery; Histamine; Indomethacin; Male; Methylene Blue; Regional Blood Flow; Tripelennamine; Vasodilation

1986
Atrial natriuretic factor and cyclic guanosine 3',5'-monophosphate in vascular smooth muscle.
    Hypertension (Dallas, Tex. : 1979), 1986, Volume: 8, Issue:9

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Atrial Natriuretic Factor; Cells, Cultured; Cyclic AMP; Cyclic GMP; Hormones; Kallikreins; Methylene Blue; Muscle, Smooth, Vascular; Nitroprusside; Rats; Rats, Inbred Strains

1986
Endothelial modulation of vascular relaxation to nitrovasodilators in aging and hypertension.
    The Journal of pharmacology and experimental therapeutics, 1986, Volume: 239, Issue:3

    Topics: Aging; Animals; Atrial Natriuretic Factor; Cyclic GMP; Dose-Response Relationship, Drug; Endothelium; Hypertension; Male; Methylene Blue; Muscle Contraction; Muscle Relaxation; Nitroprusside; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Sodium Nitrite; Vasodilator Agents

1986
Role of cyclic GMP in the modulation by endothelium of the adrenolytic action of prazosin in the rat isolated aorta.
    British journal of pharmacology, 1986, Volume: 89, Issue:3

    Topics: Animals; Aorta, Thoracic; Cyclic GMP; Endothelium; In Vitro Techniques; Male; Methylene Blue; Muscle, Smooth, Vascular; Norepinephrine; Phenoxybenzamine; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha

1986
Mechanism of antagonism of thromboxane receptors in vascular smooth muscle.
    European journal of pharmacology, 1987, Jan-06, Volume: 133, Issue:1

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Aorta; Cats; Coronary Vessels; Cyclic GMP; Dose-Response Relationship, Drug; Endothelium; In Vitro Techniques; Male; Methylene Blue; Muscle, Smooth, Vascular; Phenylacetates; Prostaglandin Endoperoxides, Synthetic; Rats; Rats, Inbred Strains; Receptors, Prostaglandin; Receptors, Thromboxane; Sulfonamides; Superoxides; Thromboxanes; Vasodilation

1987
Endothelium-dependent modulation of cGMP levels and intrinsic smooth muscle tone in isolated bovine intrapulmonary artery and vein.
    Circulation research, 1987, Volume: 60, Issue:1

    Topics: Animals; Cattle; Cyclic AMP; Cyclic GMP; Endothelium; In Vitro Techniques; Indomethacin; Methylene Blue; Muscle Contraction; Muscle, Smooth, Vascular; Phenylephrine; Pulmonary Circulation; Purinones

1987
Atrial natriuretic factor (ANF) inhibits arginine vasopressin-stimulated Ca2+ fluxes and cell contraction in vascular smooth muscle cells.
    Klinische Wochenschrift, 1987, Volume: 65 Suppl 8

    Topics: Animals; Arginine Vasopressin; Atrial Natriuretic Factor; Calcium; Cells, Cultured; Cyclic GMP; Methylene Blue; Muscle, Smooth, Vascular; Vasoconstriction

1987
Involvement of endogenous noradrenaline release in methylene blue-induced contraction of isolated rabbit aorta.
    Japanese journal of pharmacology, 1987, Volume: 44, Issue:1

    Topics: Animals; Aorta; Cyclic GMP; Electric Stimulation; Endothelium; In Vitro Techniques; Methylene Blue; Norepinephrine; Prazosin; Rabbits; Reserpine; Sympathomimetics; Time Factors; Vasoconstriction

1987
Concentration and time-dependent relationships between isosorbide dinitrate-induced relaxation and formation of cyclic GMP in coronary arterial smooth muscle.
    The Journal of pharmacology and experimental therapeutics, 1983, Volume: 224, Issue:2

    Topics: Animals; Cattle; Cyclic GMP; Guanylate Cyclase; Isosorbide Dinitrate; Methylene Blue; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular

1983
Relationship between cyclic guanosine 3':5'-monophosphate formation and relaxation of coronary arterial smooth muscle by glyceryl trinitrate, nitroprusside, nitrite and nitric oxide: effects of methylene blue and methemoglobin.
    The Journal of pharmacology and experimental therapeutics, 1981, Volume: 219, Issue:1

    Topics: Animals; Cattle; Coronary Vessels; Cyclic GMP; In Vitro Techniques; Methemoglobin; Methylene Blue; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; Nitroglycerin; Nitroprusside; Sodium Nitrite; Vasodilator Agents

1981
Vascular tolerance to nitroglycerin and cyclic GMP generation in rat aortic smooth muscle.
    The Journal of pharmacology and experimental therapeutics, 1982, Volume: 221, Issue:3

    Topics: Animals; Aorta, Thoracic; Cyclic GMP; Drug Tolerance; In Vitro Techniques; Male; Methylene Blue; Muscle Relaxation; Muscle, Smooth, Vascular; Nitroglycerin; Rats; Rats, Inbred Strains; Time Factors

1982
Function of cyclic GMP in acetylcholine-induced contraction of coronary smooth muscle.
    Naunyn-Schmiedeberg's archives of pharmacology, 1982, Volume: 319, Issue:1

    Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Acetylcholine; Animals; Cattle; Coronary Vessels; Cyclic AMP; Cyclic GMP; In Vitro Techniques; Methylene Blue; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular

1982
Nitroglycerin tolerance and cyclic GMP generation in the longitudinal smooth muscle of the guinea-pig ileum.
    The Journal of pharmacology and experimental therapeutics, 1983, Volume: 225, Issue:1

    Topics: Animals; Cyclic GMP; Dose-Response Relationship, Drug; Drug Tolerance; Female; Guinea Pigs; Ileum; Male; Methylene Blue; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Nitroglycerin; Nitroprusside; Time Factors

1983
Endothelium-induced relaxation by acetylcholine associated with larger rises in cyclic GMP in coronary arterial strips.
    Journal of cyclic nucleotide research, 1982, Volume: 8, Issue:6

    Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Acetylcholine; Animals; Cattle; Coronary Vessels; Cyclic GMP; Endothelium; In Vitro Techniques; Methylene Blue; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular

1982
A cellular mechanism for nitric oxide-mediated cholinergic control of mammalian heart rate.
    The Journal of general physiology, 1995, Volume: 106, Issue:1

    Topics: 1-Methyl-3-isobutylxanthine; Aminoquinolines; Animals; Arginine; Carbachol; Cardiotonic Agents; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; Enzyme Inhibitors; GTP-Binding Proteins; Guanylate Cyclase; Heart Rate; Isoproterenol; Methylene Blue; Molsidomine; Muscarinic Agonists; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Platelet Aggregation Inhibitors; Rabbits; Receptors, Cholinergic; Receptors, Muscarinic; Sinoatrial Node; Thionucleotides

1995
Interleukin 1 activates soluble guanylate cyclase in human vascular smooth muscle cells through a novel nitric oxide-independent pathway.
    The Journal of experimental medicine, 1994, Jan-01, Volume: 179, Issue:1

    Topics: Amino Acid Oxidoreductases; Aminoquinolines; Animals; Arginine; Base Sequence; Catecholamines; Cells, Cultured; Cyclic GMP; DNA Primers; Enzyme Activation; Guanylate Cyclase; Humans; Imidazolines; Interferon-gamma; Interleukin-1; Lipopolysaccharides; Methylene Blue; Molecular Sequence Data; Muscle, Smooth, Vascular; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Polymerase Chain Reaction; Rats; RNA, Messenger; Tumor Necrosis Factor-alpha

1994
An L-arginine-nitric oxide-cyclic guanosine monophosphate system exists in the uterus and inhibits contractility during pregnancy.
    American journal of obstetrics and gynecology, 1994, Volume: 170, Issue:1 Pt 1

    Topics: Amino Acid Oxidoreductases; Animals; Arginine; Citrulline; Culture Techniques; Cyclic GMP; Dose-Response Relationship, Drug; Female; Labor, Obstetric; Methylene Blue; NADP; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Nitroprusside; Pregnancy; Progesterone; Rats; Rats, Sprague-Dawley; Uterine Contraction; Uterus

1994
Endothelin (ET)-3 stimulates cyclic guanosine 3',5'-monophosphate production via ETB receptor by producing nitric oxide in isolated rat glomerulus, and in cultured rat mesangial cells.
    The Journal of clinical investigation, 1994, Volume: 93, Issue:2

    Topics: 1-Methyl-3-isobutylxanthine; Animals; Arginine; Calmodulin; Cells, Cultured; Cyclic GMP; Dose-Response Relationship, Drug; Egtazic Acid; Endothelin Receptor Antagonists; Endothelins; Glomerular Mesangium; Guanylate Cyclase; Hemoglobins; In Vitro Techniques; Kidney Glomerulus; Kinetics; Male; Methylene Blue; Nicardipine; Nitric Oxide; omega-N-Methylarginine; Peptide Fragments; Peptides, Cyclic; Rats; Rats, Sprague-Dawley; Receptors, Endothelin; Sulfonamides

1994
Interleukin-4 stimulates cGMP production by IFN-gamma-activated human monocytes. Involvement of the nitric oxide synthase pathway.
    The Journal of biological chemistry, 1994, Apr-01, Volume: 269, Issue:13

    Topics: Amino Acid Oxidoreductases; Aminoquinolines; Arginine; Calcium; Cells, Cultured; Cyclic GMP; Dose-Response Relationship, Drug; Egtazic Acid; Guanylate Cyclase; Humans; Interferon-gamma; Interleukin-4; Kinetics; Leukocytes, Mononuclear; Methylene Blue; Nitric Oxide Synthase; Nitroprusside; omega-N-Methylarginine

1994
Nitric oxide directly activates calcium-dependent potassium channels in vascular smooth muscle.
    Nature, 1994, Apr-28, Volume: 368, Issue:6474

    Topics: Adenosine Triphosphate; Animals; Calcium; Cell Membrane; Charybdotoxin; Cyclic GMP; Ethylmaleimide; In Vitro Techniques; Magnesium; Male; Membrane Potentials; Methylene Blue; Muscle, Smooth, Vascular; Myristic Acid; Myristic Acids; Nitric Oxide; Potassium Channels; Rabbits; Scorpion Venoms

1994
Role of the endothelium and cyclic GMP in renal vasodilator responses to cryptolepine in rats.
    Journal of cardiovascular pharmacology, 1994, Volume: 23, Issue:4

    Topics: Alkaloids; Animals; Antihypertensive Agents; Arginine; Cyclic GMP; Endothelium, Vascular; Hydroquinones; In Vitro Techniques; Indole Alkaloids; Indoles; Kidney; Male; Methylene Blue; Nitric Oxide; Nitroarginine; Potassium Chloride; Quinolines; Rats; Vasodilator Agents

1994
Insulin increases guanosine-3',5'-cyclic monophosphate in human platelets. A mechanism involved in the insulin anti-aggregating effect.
    Diabetes, 1994, Volume: 43, Issue:8

    Topics: 1-Methyl-3-isobutylxanthine; Adenosine Diphosphate; Adult; Amino Acid Oxidoreductases; Arginine; Blood Platelets; Collagen; Cyclic GMP; Female; Genistein; Guanylate Cyclase; Humans; Insulin; Isoflavones; Male; Methylene Blue; Nitric Oxide Synthase; omega-N-Methylarginine; Platelet Aggregation; Platelet Aggregation Inhibitors; Protein-Tyrosine Kinases; Radioimmunoassay; Recombinant Proteins

1994
Adenosine A3 receptors regulate serotonin transport via nitric oxide and cGMP.
    The Journal of biological chemistry, 1994, Nov-04, Volume: 269, Issue:44

    Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Amino Acid Oxidoreductases; Amino Acid Sequence; Aminoquinolines; Animals; Biological Transport; Carrier Proteins; Cell Membrane; Cyclic GMP; GTP-Binding Proteins; Imidazoles; In Vitro Techniques; Membrane Glycoproteins; Membrane Transport Proteins; Methylene Blue; Molecular Sequence Data; Nerve Tissue Proteins; Nitric Oxide; Nitric Oxide Synthase; Paroxetine; Protein Kinase C; Rats; Receptors, Purinergic P1; Second Messenger Systems; Serotonin; Serotonin Plasma Membrane Transport Proteins; Signal Transduction; Tumor Cells, Cultured

1994
Muscarinic cholinergic stimulation of the nitric oxide-cyclic GMP signaling system in cultured rat sensory neurons.
    Neuroscience, 1994, Volume: 62, Issue:2

    Topics: Acetylcholine; Amino Acid Oxidoreductases; Animals; Arginine; Atropine; Capsaicin; Carbachol; Cells, Cultured; Cyclic GMP; Embryo, Mammalian; Ganglia, Spinal; Guanylate Cyclase; Methacholine Chloride; Methylene Blue; Neurons, Afferent; Nicotine; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; omega-N-Methylarginine; Oxotremorine; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic; Signal Transduction

1994
Hypercapnic vasodilatation in isolated rat basilar arteries is exerted via low pH and does not involve nitric oxide synthase stimulation or cyclic GMP production.
    Acta physiologica Scandinavica, 1994, Volume: 152, Issue:4

    Topics: Amino Acid Oxidoreductases; Animals; Arginine; Basilar Artery; Cyclic GMP; Hydrogen-Ion Concentration; Hypercapnia; Male; Methylene Blue; Nitric Oxide Synthase; Nitroarginine; Rats; Rats, Wistar; Tetrodotoxin; Vasodilation

1994
cGMP upregulates nitric oxide synthase expression in vascular smooth muscle cells.
    Hypertension (Dallas, Tex. : 1979), 1995, Volume: 25, Issue:4 Pt 2

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Amino Acid Oxidoreductases; Animals; Cells, Cultured; Cyclic GMP; Humans; Interleukin-1; Methylene Blue; Muscle, Smooth, Vascular; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Wistar; RNA, Messenger; Tumor Necrosis Factor-alpha

1995
Nitric oxide induces an increased Na+ conductance in identified neurons of Aplysia.
    Brain research, 1995, Jan-30, Volume: 670, Issue:2

    Topics: 1-Methyl-3-isobutylxanthine; Animals; Aplysia; Cell Membrane; Cyclic GMP; Electric Conductivity; Ganglia, Invertebrate; Hydroxylamine; Hydroxylamines; Ions; Methylene Blue; Microinjections; Neurons; Nitric Oxide; Nitroprusside; Sodium

1995
Cyclic guanosine 3',5'-monophosphate mediates 3-morpholinosydnonimine-induced inhibition of human natural killer cells.
    Biochemical pharmacology, 1995, Jul-17, Volume: 50, Issue:2

    Topics: 1-Methyl-3-isobutylxanthine; Adult; Cyclic GMP; Cytotoxicity, Immunologic; Dose-Response Relationship, Drug; Humans; Interferon-gamma; Killer Cells, Natural; Methylene Blue; Molsidomine; Nitric Oxide; Tumor Cells, Cultured

1995
Interleukin 1 induces prostacyclin-dependent increases in cyclic AMP production and does not affect cyclic GMP production in human vascular smooth muscle cells.
    Cytokine, 1995, Volume: 7, Issue:5

    Topics: Aminoquinolines; Cells, Cultured; Cyclic AMP; Cyclic GMP; Cyclooxygenase Inhibitors; Enzyme Inhibitors; Epoprostenol; Guanylate Cyclase; Humans; Interleukin-1; Methylene Blue; Muscle, Smooth, Vascular; Saphenous Vein; Solubility; Vasodilator Agents

1995
Endothelium-dependent relaxation to acetylcholine in bovine oviductal arteries: mediation by nitric oxide and changes in apamin-sensitive K+ conductance.
    British journal of pharmacology, 1995, Volume: 115, Issue:7

    Topics: Acetylcholine; Animals; Apamin; Arginine; Arteries; Cattle; Cyclic GMP; Cysteine; Endothelium, Vascular; Enzyme Inhibitors; Fallopian Tubes; Female; In Vitro Techniques; Methylene Blue; Muscle Relaxation; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Ouabain; Potassium; Potassium Channel Blockers; S-Nitrosothiols

1995
Vasorelaxant effect of isoliquiritigenin, a novel soluble guanylate cyclase activator, in rat aorta.
    British journal of pharmacology, 1995, Volume: 114, Issue:8

    Topics: Aldehyde Reductase; Animals; Aorta; Chalcone; Chalcones; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Female; Guanylate Cyclase; Male; Methylene Blue; Muscle Relaxation; Muscle, Smooth, Vascular; Phenylephrine; Platelet Aggregation Inhibitors; Pyrrolidinones; Quinolones; Rats; Rats, Wistar; Rolipram

1995
Metabolism of the genotoxicant 2-nitropropane to a nitric oxide species.
    Chemico-biological interactions, 1995, Jul-14, Volume: 97, Issue:2

    Topics: Animals; Cyclic GMP; Enzyme-Linked Immunosorbent Assay; Hydrazines; Liver; Male; Methylene Blue; Mice; Mice, Inbred BALB C; Microsomes; Nitric Oxide; Nitrites; Nitrogen Oxides; Nitroparaffins; Propane; Rats; Rats, Sprague-Dawley; Solvents; Spectrophotometry

1995
Role of nitric oxide in restitution of injured guinea pig gastric mucosa in vitro.
    The American journal of physiology, 1995, Volume: 268, Issue:6 Pt 1

    Topics: Animals; Arginine; Bicarbonates; Cyclic GMP; Dibutyryl Cyclic GMP; Gastric Mucosa; Guinea Pigs; Hydrogen-Ion Concentration; In Vitro Techniques; Male; Mannitol; Methylene Blue; Microscopy, Electron; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitroprusside; omega-N-Methylarginine; Saline Solution, Hypertonic; Stereoisomerism; Time Factors

1995
Nitric oxide/cyclic guanosine monophosphate system in the spinal cord differentially modulates intracerebroventricularly administered morphine- and beta-endorphin-induced antinociception in the mouse.
    The Journal of pharmacology and experimental therapeutics, 1995, Volume: 274, Issue:1

    Topics: Analgesics; Animals; Arginine; beta-Endorphin; Cyclic GMP; Dose-Response Relationship, Drug; Hemoglobins; Injections, Intraventricular; Injections, Spinal; Male; Methylene Blue; Mice; Mice, Inbred ICR; Morphine; Nitric Oxide; Oligopeptides; Spinal Cord

1995
Inhibition of vascular nitric oxide-cGMP pathway by plasma from ischemic hindlimb of rats.
    The American journal of physiology, 1995, Volume: 269, Issue:1 Pt 2

    Topics: Acetylcholine; Animals; Aorta; Blood Physiological Phenomena; Blood Vessels; Cyclic GMP; Hindlimb; In Vitro Techniques; Ischemia; Methylene Blue; Nitric Oxide; Nitroglycerin; Rats; Rats, Sprague-Dawley; Reference Values

1995
Relaxant effects of nitric oxide and cyclic GMP on pregnant rat uterine longitudinal smooth muscle.
    European journal of obstetrics, gynecology, and reproductive biology, 1995, Volume: 60, Issue:2

    Topics: Animals; Calcium; Carbachol; Cyclic GMP; Female; Guanosine 5'-O-(3-Thiotriphosphate); Methylene Blue; Muscle Relaxation; Myometrium; Nitric Oxide; Nitroprusside; Potassium Chloride; Pregnancy; Rats; Rats, Sprague-Dawley; Uterine Contraction

1995
Evidence for the involvement of cGMP in neural bronchodilator responses in humal trachea.
    The Journal of physiology, 1995, Mar-01, Volume: 483 ( Pt 2)

    Topics: Adenosine Monophosphate; Adolescent; Adult; Arginine; Bronchoconstriction; Child; Chymotrypsin; Cyclic GMP; Electric Conductivity; Epithelium; Female; Humans; Male; Methylene Blue; Middle Aged; Molsidomine; Muscle, Smooth; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitroprusside; Tetrodotoxin; Time Factors; Trachea; Vasoactive Intestinal Peptide; Vasodilator Agents

1995
Potentiation of the hyporeactivity induced by in vivo endothelial injury in the rat carotid artery by chronic treatment with fish oil.
    British journal of pharmacology, 1995, Volume: 115, Issue:2

    Topics: Analysis of Variance; Animals; Arginine; Blood Pressure; Body Weight; Carotid Arteries; Carotid Artery Injuries; Catheterization; Cyclic GMP; Endothelium, Vascular; Fatty Acids; Fish Oils; Indomethacin; Isometric Contraction; Male; Methylene Blue; Molsidomine; Muscle, Smooth, Vascular; Nitric Oxide; Nitroarginine; Phenylephrine; Rats; Rats, Wistar; Superoxide Dismutase; Vascular Resistance; Vasodilator Agents

1995
Control of cardiac muscle cell function by an endogenous nitric oxide signaling system.
    Proceedings of the National Academy of Sciences of the United States of America, 1993, Jan-01, Volume: 90, Issue:1

    Topics: Aging; Amino Acid Oxidoreductases; Animals; Animals, Newborn; Arginine; Carbachol; Cells, Cultured; Cyclic GMP; Heart; Heart Rate; Heart Ventricles; Isoproterenol; Methylene Blue; Myocardial Contraction; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Oxyhemoglobins; Rats; Signal Transduction

1993
Inhibition of nitric oxide synthesis by methylene blue.
    Biochemical pharmacology, 1993, Jan-26, Volume: 45, Issue:2

    Topics: Amino Acid Oxidoreductases; Animals; Calcimycin; Cattle; Cells, Cultured; Cyclic GMP; Cytochrome c Group; Endothelium, Vascular; Guanylate Cyclase; Methylene Blue; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; Nitric Oxide Synthase; Swine

1993
Vasoactive intestinal peptide stimulation of cyclic guanosine monophosphate formation: further evidence for a role of nitric oxide synthase and cytosolic guanylate cyclase in rat pinealocytes.
    Endocrinology, 1993, Volume: 132, Issue:6

    Topics: Amino Acid Oxidoreductases; Animals; Arginine; Cyclic GMP; Cytosol; Drug Synergism; Guanylate Cyclase; Methylene Blue; Nitric Oxide Synthase; omega-N-Methylarginine; Phenylephrine; Pineal Gland; Rats; Vasoactive Intestinal Peptide

1993
Effects of methylene blue on blood pressure and reactivity to norepinephrine in endotoxemic rats.
    Journal of cardiovascular pharmacology, 1993, Volume: 21, Issue:6

    Topics: Animals; Blood Pressure; Cyclic GMP; Dose-Response Relationship, Drug; Endotoxins; Escherichia coli; Lipopolysaccharides; Male; Methylene Blue; Norepinephrine; Rats; Rats, Wistar; Toxemia

1993
Ca(++)-dependent constitutive nitric oxide synthase is not involved in the cyclic GMP-increasing effects of carbachol in ventricular cardiomyocytes.
    The Journal of pharmacology and experimental therapeutics, 1993, Volume: 266, Issue:2

    Topics: Amino Acid Oxidoreductases; Animals; Calcium; Carbachol; Cyclic GMP; GTP-Binding Proteins; Guinea Pigs; In Vitro Techniques; Methylene Blue; Myocardial Contraction; Myocardium; Nitric Oxide Synthase; Pertussis Toxin; Pteridines; Pterins; Virulence Factors, Bordetella

1993
Involvement of nitric oxide in the endothelium-dependent relaxation induced by hydrogen peroxide in the rabbit aorta.
    British journal of pharmacology, 1993, Volume: 110, Issue:1

    Topics: Amino Acid Oxidoreductases; Animals; Aorta, Thoracic; Arginine; Cyclic GMP; Endothelium, Vascular; Female; Hydrogen Peroxide; In Vitro Techniques; Male; Methylene Blue; Muscle Relaxation; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Rabbits

1993
Cyclic GMP-linked pathway for renin secretion.
    Kidney international, 1994, Volume: 46, Issue:6

    Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Aminoquinolines; Animals; Atrial Natriuretic Factor; Cyclic GMP; Guanylate Cyclase; In Vitro Techniques; Kidney Cortex; Methylene Blue; Nitroprusside; Peptide Fragments; Purinones; Rats; Renin; Second Messenger Systems

1994
Effects of topical methylene blue on cyclic GMP level, blood flow, and O2 consumption in focal cerebral ischaemia.
    Neurological research, 1994, Volume: 16, Issue:6

    Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Administration, Topical; Analysis of Variance; Animals; Blood Pressure; Brain; Carbon Dioxide; Cerebral Cortex; Cerebrovascular Circulation; Cyclic GMP; Guanylate Cyclase; Heart Rate; Hemodynamics; Hemoglobins; Ischemic Attack, Transient; Male; Methylene Blue; Oxygen Consumption; Partial Pressure; Pons; Rats; Regional Blood Flow

1994
Possible involvement of nitric oxide in carbachol-induced activation of transglutaminase in rat superior cervical sympathetic ganglia.
    Neuroscience research, 1995, Volume: 21, Issue:3

    Topics: Animals; Arginine; Calcium; Carbachol; Cyclic GMP; Enzyme Activation; Female; Hemoglobins; In Vitro Techniques; Male; Methylene Blue; Nitric Oxide; omega-N-Methylarginine; Rats; Rats, Wistar; Superior Cervical Ganglion; Transglutaminases

1995
Atrial natriuretic factor stimulates migration by human neutrophils.
    European journal of pharmacology, 1995, Feb-15, Volume: 288, Issue:3

    Topics: Aminoquinolines; Atrial Natriuretic Factor; Auranofin; Cell Movement; Cells, Cultured; Cyclic GMP; Guanosine Triphosphate; Humans; Methylene Blue; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pertussis Toxin; Virulence Factors, Bordetella

1995
The role of carbon monoxide in lucigenin-dependent chemiluminescence of rat alveolar macrophages.
    European journal of pharmacology, 1995, Mar-15, Volume: 289, Issue:1

    Topics: Acridines; Analysis of Variance; Animals; Blotting, Northern; Carbon Monoxide; Cyclic GMP; Guanylate Cyclase; Heme Oxygenase (Decyclizing); In Vitro Techniques; Luminescent Measurements; Macrophages, Alveolar; Methylene Blue; Protoporphyrins; Rats; Rats, Sprague-Dawley

1995
Role of nitric oxide/cyclic GMP in i.c.v. administered beta-endorphin- and (+)-cis-dioxolane-induced antinociception in the mouse.
    European journal of pharmacology, 1994, Sep-12, Volume: 262, Issue:3

    Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesia; Analgesics; Animals; Arginine; beta-Endorphin; Cyclic GMP; Dioxolanes; Dose-Response Relationship, Drug; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Hemoglobins; Injections, Intraventricular; Male; Methylene Blue; Mice; Mice, Inbred ICR; Morphine; Narcotic Antagonists; Nitric Oxide; Nitroarginine; Pyrrolidines; Receptors, Opioid; Receptors, Opioid, kappa; Stereoisomerism

1994
Comparative analysis of vasodilating mechanisms of Ki1769, Ki3315 and KRN2391, pyridinecarboximidamide derivatives, in porcine isolated coronary artery.
    General pharmacology, 1994, Volume: 25, Issue:5

    Topics: Animals; Coronary Vessels; Cyclic GMP; Glyburide; In Vitro Techniques; Methylene Blue; Potassium Channels; Pyridines; Swine; Vasodilation; Vasodilator Agents

1994
Cyclic GMP and guanylate cyclase mediate lipopolysaccharide-induced Kupffer cell tumor necrosis factor-alpha synthesis.
    Journal of leukocyte biology, 1995, Volume: 57, Issue:2

    Topics: Aminoquinolines; Animals; Cell Membrane Permeability; Cells, Cultured; Cyclic GMP; Dibutyryl Cyclic GMP; Guanylate Cyclase; Kupffer Cells; Lipopolysaccharides; Male; Methylene Blue; Nitric Oxide; Nitroprusside; Rats; Rats, Sprague-Dawley; Second Messenger Systems; SRS-A; Stimulation, Chemical; Tumor Necrosis Factor-alpha

1995
Mechanisms whereby macrophage-derived nitric oxide is involved in morphine-induced suppression of splenic lymphocyte proliferation.
    The Journal of pharmacology and experimental therapeutics, 1995, Volume: 272, Issue:2

    Topics: Aminoquinolines; Animals; Cyclic GMP; Hemoglobins; Immunosuppressive Agents; Lymphocyte Activation; Macrophages; Male; Methylene Blue; Morphine; Nitric Oxide; Rats; Rats, Inbred Lew; Spleen; Superoxide Dismutase

1995
Methylene blue inhibits the stimulation of bone mass by high doses of estradiol in male rats.
    Endocrine regulations, 1994, Volume: 28, Issue:3

    Topics: Animals; Bone Density; Cyclic GMP; Dose-Response Relationship, Drug; Estradiol; Estrogen Antagonists; Femur; Guanylate Cyclase; Male; Methylene Blue; Minerals; Rats; Rats, Sprague-Dawley; Seminal Vesicles; Sex Characteristics

1994
Regulation of bradykinin sensitivity in peripheral sensory fibres of the neonatal rat by nitric oxide and cyclic GMP.
    Neuropharmacology, 1994, Volume: 33, Issue:10

    Topics: Animals; Animals, Newborn; Arginine; Bradykinin; Concanavalin A; Cyclic GMP; Indazoles; Methylene Blue; Nitric Oxide; Nitroprusside; Nociceptors; Rats; Receptors, Bradykinin; Spinal Cord

1994
cGMP mediates the desensitization to bradykinin in isolated canine coronary arteries.
    The American journal of physiology, 1995, Volume: 268, Issue:2 Pt 2

    Topics: Animals; Arginine; Arteries; Bradykinin; Coronary Vessels; Cyclic GMP; Dogs; Drug Resistance; In Vitro Techniques; Methylene Blue; Molsidomine; Nitroarginine; Oxyhemoglobins; Potassium; Vasodilation; Vasodilator Agents

1995
Methylene blue induces cytotoxicity in human brain tumor cells.
    Cancer letters, 1995, Jan-27, Volume: 88, Issue:2

    Topics: Astrocytoma; Brain Neoplasms; Calcium; Cell Division; Cyclic GMP; Humans; Intracellular Fluid; Kinetics; Methylene Blue; Neuroblastoma; Reactive Oxygen Species; Tumor Cells, Cultured

1995
Modification by LY 83583 and methylene blue of relaxation induced by nitric oxide, glyceryl trinitrate, sodium nitroprusside and atriopeptin in aortae of the rat, guinea-pig and rabbit.
    General pharmacology, 1994, Volume: 25, Issue:7

    Topics: Aminoquinolines; Animals; Aorta, Thoracic; Atrial Natriuretic Factor; Cyclic GMP; Drug Interactions; Enzyme Activation; Guanylate Cyclase; Guinea Pigs; In Vitro Techniques; Male; Methylene Blue; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; Nitroglycerin; Nitroprusside; Rabbits; Rats; Rats, Wistar; Vasodilator Agents

1994
Effects of the agents affecting cyclic nucleotide metabolism on the bradykinin- and des-Arg9-bradykinin-induced relaxations and contractions in isolated rat duodenum.
    General pharmacology, 1994, Volume: 25, Issue:7

    Topics: Animals; Bradykinin; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Duodenum; Imidazoles; In Vitro Techniques; Male; Methylene Blue; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Niacin; Rats; Receptors, Bradykinin; Thromboxane-A Synthase

1994
Bradykinin and capsaicin stimulate cyclic GMP production in cultured rat dorsal root ganglion neurons via a nitrosyl intermediate.
    Journal of neuroscience research, 1993, Oct-15, Volume: 36, Issue:3

    Topics: Animals; Arginine; Bradykinin; Bradykinin Receptor Antagonists; Calcium; Capsaicin; Cells, Cultured; Cyclic GMP; Ganglia, Spinal; Guanylate Cyclase; Methylene Blue; Neurons; Nitric Oxide; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley; Receptors, Bradykinin

1993
Blockers of the L-arginine-nitric oxide-cyclic GMP pathway facilitate baroreceptor resetting.
    Hypertension (Dallas, Tex. : 1979), 1994, Volume: 23, Issue:1 Suppl

    Topics: Analysis of Variance; Animals; Aorta; Aortic Coarctation; Arginine; Blood Pressure; Cyclic GMP; Glyburide; Guanylate Cyclase; Male; Methylene Blue; Muscle, Smooth, Vascular; Nitric Oxide; Nitroarginine; Pressoreceptors; Rats; Rats, Wistar

1994
Cyclic guanosine monophosphate mediates penile erection in the rat.
    European urology, 1993, Volume: 24, Issue:4

    Topics: Alprostadil; Animals; Calcitonin Gene-Related Peptide; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Ethylmaleimide; Glutamates; Glutamic Acid; Male; Methylene Blue; Muscle Relaxation; N-Methylaspartate; Neurotransmitter Agents; Nitroprusside; Papaverine; Penile Erection; Rats; Rats, Sprague-Dawley; Vasoactive Intestinal Peptide

1993
Relaxation of retinal pericyte contractile tone through the nitric oxide-cyclic guanosine monophosphate pathway.
    Investigative ophthalmology & visual science, 1994, Volume: 35, Issue:3

    Topics: Animals; Capillaries; Cattle; Cell Movement; Cells, Cultured; Cyclic GMP; Guanylate Cyclase; Methylene Blue; Nitric Oxide; Nitroprusside; Radioimmunoassay; Retinal Vessels

1994
Nitric oxide has no chronotropic effect in right atria isolated from rat heart.
    European journal of pharmacology, 1994, Apr-01, Volume: 255, Issue:1-3

    Topics: Acetylcholine; Aminoquinolines; Animals; Aorta, Thoracic; Arginine; Cyclic GMP; Guanylate Cyclase; Heart Atria; Heart Rate; In Vitro Techniques; Male; Methylene Blue; Molsidomine; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitroarginine; Norepinephrine; Parasympathetic Nervous System; Rats; Rats, Sprague-Dawley; Sympathetic Nervous System; Vasodilator Agents

1994
Basal and KCl-stimulated corticotropin-releasing hormone release from human placental syncytiotrophoblasts is inhibited by sodium nitroprusside.
    The Journal of clinical endocrinology and metabolism, 1994, Volume: 79, Issue:2

    Topics: Calcium-Calmodulin-Dependent Protein Kinases; Cell Membrane; Cells, Cultured; Corticotropin-Releasing Hormone; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; Female; Guanylate Cyclase; Humans; Membrane Potentials; Methylene Blue; Nitroprusside; Potassium Chloride; Pregnancy; Protein Kinase C; Protein Kinases; Trophoblasts

1994
Exogenous nitric oxide inhibits proliferation of cultured vascular endothelial cells.
    Biochemical and biophysical research communications, 1994, Sep-15, Volume: 203, Issue:2

    Topics: Animals; Cattle; Cell Division; Cells, Cultured; Cyclic GMP; DNA; Embryo, Mammalian; Endothelium, Vascular; Guanylate Cyclase; Methylene Blue; Nitric Oxide; Nitroglycerin; Nitroprusside; Thymidine

1994
Non-adrenergic, non-cholinergic relaxation and levels of cyclic nucleotides in rabbit lower urinary tract.
    European journal of pharmacology, 1994, Jul-15, Volume: 268, Issue:2

    Topics: Animals; Arginine; Cyclic AMP; Cyclic GMP; Electric Stimulation; Female; In Vitro Techniques; Methylene Blue; Muscle Relaxation; Nitric Oxide; Nitroarginine; Rabbits; Urethra

1994
Inhibitory effect of sodium nitroprusside on the relaxing action of isoproterenol in isolated rat urinary bladder.
    General pharmacology, 1994, Volume: 25, Issue:4

    Topics: Animals; Cyclic GMP; Dobutamine; Electric Stimulation; In Vitro Techniques; Isoproterenol; Male; Methylene Blue; Muscle Relaxation; Nitroprusside; Rats; Rats, Wistar; Receptors, Adrenergic, beta; Urinary Bladder

1994
Pharmacologic evidence that spinal muscarinic analgesia is mediated by an L-arginine/nitric oxide/cyclic GMP cascade in rats.
    The Journal of pharmacology and experimental therapeutics, 1994, Volume: 271, Issue:2

    Topics: Analgesia; Animals; Arginine; Cyclic GMP; Dioxolanes; Dose-Response Relationship, Drug; Injections, Spinal; Male; Methylene Blue; Muscarinic Agonists; Nitric Oxide; Nitroarginine; Rats; Rats, Sprague-Dawley; Spinal Cord

1994
Nitric oxide formation does not underlie the memory deficits produced by ibotenate injections into the nucleus basalis of rats.
    Behavioral neuroscience, 1994, Volume: 108, Issue:2

    Topics: Animals; Brain Mapping; Cerebral Cortex; Choline O-Acetyltransferase; Cyclic GMP; Discrimination Learning; Ibotenic Acid; Male; Mental Recall; Methylene Blue; Neurons; Neuropeptide Y; Nitric Oxide; Nitroprusside; Orientation; Quisqualic Acid; Rats; Receptors, AMPA; Receptors, GABA; Retention, Psychology; Substantia Innominata

1994
Methylene blue inhibits the antithrombotic effect of nitroglycerin.
    Journal of the American College of Cardiology, 1993, Volume: 21, Issue:1

    Topics: Animals; Antifibrinolytic Agents; Aorta; Cyclic GMP; Drug Evaluation, Preclinical; Fibrinolytic Agents; Guanylate Cyclase; Indium Radioisotopes; Infusions, Intravenous; Methylene Blue; Nitroglycerin; Platelet Aggregation; Swine; Thrombosis

1993
Lack of role of endothelium-derived relaxing factor in effects of alpha-adrenergic agonists in cutaneous veins in humans.
    The American journal of physiology, 1993, Volume: 264, Issue:2 Pt 2

    Topics: Adrenergic alpha-Agonists; Adult; Angiotensin II; Bradykinin; Cyclic GMP; Dose-Response Relationship, Drug; Female; Hand; Humans; Labetalol; Male; Methylene Blue; Nitric Oxide; Skin; Vasoconstriction; Veins

1993
Evidence against vasoactive intestinal polypeptide as the relaxant neurotransmitter in human cavernosal smooth muscle.
    British journal of pharmacology, 1993, Volume: 108, Issue:2

    Topics: Arginine; Chymotrypsin; Cyclic GMP; Electric Stimulation; Humans; Male; Methylene Blue; Muscle Relaxation; Muscle, Smooth; Neurotransmitter Agents; Nitric Oxide; Nitroarginine; Penis; Vasoactive Intestinal Peptide

1993
Adrenergic stimulation of cyclic GMP formation requires NO-dependent activation of cytosolic guanylate cyclase in rat pinealocytes.
    Journal of neurochemistry, 1993, Volume: 61, Issue:1

    Topics: Animals; Arginine; Cells, Cultured; Cyclic GMP; Cytosol; Enzyme Activation; Guanylate Cyclase; Methylene Blue; Nitric Oxide; omega-N-Methylarginine; Pineal Gland; Rats; Sympathomimetics

1993
Characterization of soluble guanylyl cyclase in transformed human non-pigmented epithelial cells.
    Biochemical and biophysical research communications, 1993, Sep-15, Volume: 195, Issue:2

    Topics: Blotting, Northern; Cell Line, Transformed; Cyclic GMP; Dose-Response Relationship, Drug; Epithelium; Guanylate Cyclase; Humans; Isoenzymes; Kinetics; Macromolecular Substances; Methylene Blue; Nitroprusside; RNA, Messenger

1993
Notes on the acetylcholine-induced relaxation of porcine coronary arteries.
    Life sciences, 1994, Volume: 54, Issue:8

    Topics: Acetylcholine; Animals; Arginine; Coronary Vessels; Cyclic GMP; Dose-Response Relationship, Drug; Drug Synergism; Endothelium, Vascular; Methylene Blue; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; omega-N-Methylarginine; Radioimmunoassay; Swine; Vasoconstriction; Vasodilation

1994
Vasoinhibitory action of KT2-734, an antihypertensive agent, in isolated rat aorta.
    European journal of pharmacology, 1994, Jan-04, Volume: 251, Issue:1

    Topics: Animals; Antihypertensive Agents; Aorta, Thoracic; Atropine; Calcium Channel Blockers; Cyclic AMP; Cyclic GMP; Endothelium, Vascular; Imidazoles; In Vitro Techniques; Isometric Contraction; Male; Methylene Blue; Muscle Contraction; Muscle, Smooth, Vascular; Nitric Oxide; Propranolol; Rats; Rats, Wistar; Serotonin Antagonists

1994
Intracellular mechanism of penile erection in monkeys.
    Neurourology and urodynamics, 1994, Volume: 13, Issue:1

    Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Alprostadil; Animals; Benzopyrans; Cromakalim; Cyclic AMP; Cyclic GMP; Ethylmaleimide; Macaca nemestrina; Male; Methylene Blue; Nitroprusside; Penile Erection; Penis; Phosphodiesterase Inhibitors; Purinones; Pyrroles; Ultrasonography

1994
Anterior pituitary weight, cAMP, cGMP and prolactin levels after combined treatment with estradiol and methylene blue.
    Physiological research, 1993, Volume: 42, Issue:6

    Topics: Animals; Cyclic AMP; Cyclic GMP; Drug Interactions; Estradiol; Male; Methylene Blue; Organ Size; Pituitary Gland, Anterior; Prolactin; Rats; Rats, Wistar

1993
Methylene blue reverses endotoxin-induced hypotension.
    Circulation research, 1994, Volume: 74, Issue:6

    Topics: Animals; Blood Pressure; Cyclic GMP; Hypotension; Lipopolysaccharides; Methylene Blue; Nitric Oxide; Rabbits; Shock, Septic; Sulfhydryl Compounds

1994
Anterior pituitary weight, cAMP, cGMP and prolactin levels after combined treatment with estradiol and methylene blue.
    Physiological research, 1993, Volume: 42, Issue:3

    Topics: Animals; Body Weight; Cyclic AMP; Cyclic GMP; Estradiol; Estrogen Antagonists; Male; Methylene Blue; Organ Size; Pituitary Gland, Anterior; Prolactin; Radioimmunoassay; Rats; Rats, Wistar; Thyroxine

1993
Effects of KRN2391, a novel vasodilator, on pancreatic exocrine secretion in anesthetized dogs.
    European journal of pharmacology, 1993, Nov-02, Volume: 249, Issue:1

    Topics: Animals; Bicarbonates; Cyclic AMP; Cyclic GMP; Dogs; Female; Guanidines; Male; Methylene Blue; Nitroprusside; Pancreas; Pancreatic Juice; Pinacidil; Proteins; Pyridines; Secretin; Sincalide; Vasodilator Agents

1993
Nitric oxide-induced microvascular permeability alterations: a regulatory role for cGMP.
    The American journal of physiology, 1993, Volume: 265, Issue:6 Pt 2

    Topics: Animals; Arginine; Atrial Natriuretic Factor; Capillary Permeability; Cats; Cyclic GMP; Intestines; Methylene Blue; Molsidomine; NG-Nitroarginine Methyl Ester; Nitric Oxide; Regional Blood Flow

1993
Changes in cytosolic cGMP and calcium in airway smooth muscle relaxed by 3-morpholinosydnonimine.
    The American journal of physiology, 1994, Volume: 266, Issue:1 Pt 1

    Topics: Animals; Calcium; Cyclic AMP; Cyclic GMP; Cytosol; Dogs; Female; In Vitro Techniques; Male; Methylene Blue; Molsidomine; Muscle Relaxation; Muscle, Smooth; Osmolar Concentration; Trachea

1994
Methylene blue enhanced photorelaxation in aorta, pulmonary artery and corpus cavernosum.
    Biochemical and biophysical research communications, 1993, Jan-29, Volume: 190, Issue:2

    Topics: Animals; Aorta; Arginine; Cyclic GMP; Hemoglobins; Male; Methylene Blue; Muscle Relaxation; Muscle, Smooth, Vascular; Nitroarginine; Penis; Photosensitizing Agents; Pulmonary Artery; Rabbits; Ultraviolet Rays

1993
Hypoxia causes an abnormal contractile response in the atherosclerotic rabbit aorta. Implication of reduced nitric oxide and cGMP production.
    Circulation research, 1993, Volume: 72, Issue:3

    Topics: Animals; Aorta; Arginine; Arteriosclerosis; Calcium; Cell Hypoxia; Cyclic GMP; Disease Models, Animal; Endothelium, Vascular; Male; Methylene Blue; Nitric Oxide; Nitroarginine; Rabbits; Serotonin; Vasoconstriction

1993
Nitric oxide and cGMP: mediators of pelvic nerve-stimulated erection in dogs.
    The American journal of physiology, 1993, Volume: 264, Issue:2 Pt 2

    Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Animals; Arginine; Cyclic GMP; Dogs; Electric Stimulation; Male; Methylene Blue; Nervous System Physiological Phenomena; NG-Nitroarginine Methyl Ester; Nitric Oxide; Pelvis; Penile Erection; Purinones

1993
Influence of endothelium on induction of the L-arginine-nitric oxide pathway in rat aortas.
    The American journal of physiology, 1993, Volume: 264, Issue:4 Pt 2

    Topics: Animals; Aorta; Arginine; Cyclic GMP; Cycloheximide; Endothelium, Vascular; Male; Methylene Blue; Neural Pathways; Nitric Oxide; Norepinephrine; omega-N-Methylarginine; Rats; Rats, Wistar; Time Factors

1993
Modification by cGMP of glibenclamide-sensitive K+ currents in Xenopus oocytes.
    Japanese journal of pharmacology, 1993, Volume: 61, Issue:3

    Topics: Animals; Benzopyrans; Cromakalim; Cyclic GMP; Female; Glyburide; In Vitro Techniques; Membrane Potentials; Methylene Blue; Niacinamide; Nicorandil; Nitroprusside; Oocytes; Potassium Channels; Pyridines; Pyrroles; Xenopus laevis

1993
Endothelin-3-induced relaxation of rat thoracic aorta: a role for nitric oxide formation.
    British journal of pharmacology, 1993, Volume: 108, Issue:4

    Topics: Acetylcholine; Animals; Aorta, Thoracic; Arginine; Calmodulin; Cyclic GMP; Endothelins; Hemoglobins; Imidazoles; In Vitro Techniques; Male; Methylene Blue; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; Nitroarginine; Rats; Rats, Wistar

1993
L-arginine exerts a dual role in nociceptive processing in the brain: involvement of the kyotorphin-Met-enkephalin pathway and NO-cyclic GMP pathway.
    British journal of pharmacology, 1993, Volume: 109, Issue:1

    Topics: Analgesics; Animals; Arginine; Brain; Cyclic GMP; Endorphins; Enkephalin, Methionine; Injections, Intraventricular; Male; Methylene Blue; Mice; Mice, Inbred Strains; Naloxone; Naltrexone; Narcotic Antagonists; Neural Pathways; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nociceptors; Pain Measurement; Spinal Cord

1993
Attenuation of contractions to acetylcholine in canine bronchi by an endogenous nitric oxide-like substance.
    British journal of pharmacology, 1993, Volume: 109, Issue:3

    Topics: Acetylcholine; Animals; Arginine; Bronchi; Catalase; Cyclic GMP; Dogs; Female; In Vitro Techniques; Isometric Contraction; Male; Methylene Blue; Muscle, Smooth; Nitric Oxide; Nitroarginine; Oxyhemoglobins; Superoxide Dismutase

1993
Interactions of nitrovasodilators and atrial natriuretic peptide in isolated dog coronary arteries.
    European journal of pharmacology, 1993, Jun-11, Volume: 237, Issue:1

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Atrial Natriuretic Factor; Coronary Vessels; Cyclic GMP; Dinoprost; Dogs; Epoprostenol; Female; In Vitro Techniques; Isometric Contraction; Male; Methylene Blue; Muscle Relaxation; Muscle, Smooth, Vascular; Nitrates; Nitroglycerin; Nitroprusside; Oxyhemoglobins; Papaverine; Platelet Aggregation Inhibitors; Vasodilator Agents

1993
Direct inhibitory effect of neurotensin on isolated gastric smooth muscle cells of guinea pig via the cyclic GMP system.
    Digestion, 1993, Volume: 54, Issue:3

    Topics: Animals; Carbachol; Cells, Cultured; Cyclic GMP; Dideoxyadenosine; Guinea Pigs; In Vitro Techniques; Male; Methylene Blue; Muscle Contraction; Muscle, Smooth; Neurotensin; Stomach

1993
Mechanism of bradykinin-induced cyclic GMP accumulation in bovine tracheal smooth muscle.
    Lung, 1995, Volume: 173, Issue:6

    Topics: Animals; Arginine; Bradykinin; Calcium; Cattle; Cyclic GMP; Dose-Response Relationship, Drug; Enzyme Inhibitors; Immunohistochemistry; In Vitro Techniques; Methylene Blue; Muscle, Smooth; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Pyrogallol; Superoxide Dismutase; Trachea

1995
Chlorpromazine inhibits nitric oxide-mediated increase in intracellular cGMP in a mouse teratocarcinoma cell line.
    Inflammation research : official journal of the European Histamine Research Society ... [et al.], 1995, Volume: 44, Issue:7

    Topics: Adenosine Diphosphate Ribose; Animals; Antipsychotic Agents; Autoradiography; Cell Survival; Chlorpromazine; Cyclic GMP; Hippocampus; Immunoenzyme Techniques; Male; Methylene Blue; Mice; Nitric Oxide; Nitroprusside; Teratocarcinoma; Testicular Neoplasms; Tumor Cells, Cultured

1995
Excitation of cells in the rostral medial medulla of the rat by the nitric oxide-cyclic guanosine monophosphate messenger system.
    Neuroscience letters, 1995, Aug-11, Volume: 195, Issue:3

    Topics: Animals; Arginine; Cyclic GMP; Electrophysiology; Female; Guanosine Monophosphate; Iron; Medulla Oblongata; Methylene Blue; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Nitroarginine; Raphe Nuclei; Rats; Rats, Sprague-Dawley; Rosaniline Dyes; Second Messenger Systems

1995
Effects of nitric oxide on detrusor relaxation.
    The Journal of urology, 1996, Volume: 155, Issue:6

    Topics: Animals; Arginine; Cyclic GMP; In Vitro Techniques; Isometric Contraction; Male; Methylene Blue; Muscle, Smooth; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Pyrogallol; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Streptozocin; Ultraviolet Rays; Urinary Bladder

1996
Sodium nitroprusside stimulates Ca2+ -activated K+ channels in porcine tracheal smooth muscle cells.
    The American journal of physiology, 1996, Volume: 270, Issue:3 Pt 1

    Topics: Adenosine Triphosphate; Aminoquinolines; Animals; Calcium; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Enzyme Inhibitors; Guanylate Cyclase; In Vitro Techniques; Membrane Potentials; Methylene Blue; Muscle, Smooth; Nitroprusside; Patch-Clamp Techniques; Potassium Channels; Regression Analysis; Swine; Thionucleotides; Trachea

1996
Nitric oxide-sensitive and -insensitive contractions of the isolated rabbit iris sphincter muscle.
    Investigative ophthalmology & visual science, 1996, Volume: 37, Issue:7

    Topics: Animals; Arginine; Benzoates; Carbachol; Cyclic GMP; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Guanylate Cyclase; Imidazoles; Iris; Male; Methylene Blue; Miotics; Muscle Contraction; Muscle, Smooth; Neurokinin A; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; Pupil; Rabbits; Receptors, Cholinergic

1996
Nitric oxide inhibition attenuates systemic hypotension produced by protamine.
    The Journal of thoracic and cardiovascular surgery, 1996, Volume: 111, Issue:6

    Topics: Animals; Arginine; Blood Pressure; Cardiac Output; Cyclic GMP; Dogs; Endothelium, Vascular; Enzyme Inhibitors; Female; Hemodynamics; Heparin; Hypotension; In Vitro Techniques; Male; Methylene Blue; Models, Cardiovascular; Myocardial Contraction; Nitric Oxide; omega-N-Methylarginine; Protamines; Rabbits

1996
Tricyclic antidepressants inhibit human natural killer cells.
    Toxicology and applied pharmacology, 1996, Volume: 137, Issue:2

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adult; Antidepressive Agents, Tricyclic; Cyclic GMP; Cytotoxicity, Immunologic; Humans; Intracellular Fluid; Killer Cells, Natural; Methylene Blue; Stimulation, Chemical

1996
An endogenous protectant effect of cardiac cyclic GMP against reperfusion-induced ventricular fibrillation in the rat heart.
    British journal of pharmacology, 1995, Volume: 116, Issue:7

    Topics: Animals; Cyclic GMP; Disease Susceptibility; Electrocardiography; Hemodynamics; In Vitro Techniques; Male; Methylene Blue; Myocardial Reperfusion Injury; Nucleotides, Cyclic; Phosphodiesterase Inhibitors; Purinones; Rats; Rats, Wistar; Ventricular Fibrillation

1995
Thrombin-stimulated phospholipase C activity is inhibited without visible delay by a rapid increase in the cyclic GMP levels induced by sodium nitroprusside.
    Molecular pharmacology, 1996, Volume: 50, Issue:2

    Topics: Calcium; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Humans; Methylene Blue; Nitroprusside; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Serotonin; Thrombin; Type C Phospholipases

1996
Involvement of platelet cyclic GMP but not cyclic AMP suppression in leukocyte-dependent platelet adhesion to endothelial cells induced by platelet-activating factor in vitro.
    British journal of pharmacology, 1996, Volume: 117, Issue:2

    Topics: Animals; Blood Platelets; Cyclic AMP; Cyclic GMP; Cyclooxygenase Inhibitors; Endothelium, Vascular; Humans; In Vitro Techniques; Indomethacin; Leukocytes; Methylene Blue; Neutrophils; Nitric Oxide; Nitroprusside; Phosphodiesterase Inhibitors; Platelet Activating Factor; Platelet Adhesiveness; Purinones; Rabbits

1996
Induction of guinea pig airway hyperresponsiveness by inactivation of guanylate cyclase.
    European journal of pharmacology, 1996, Apr-29, Volume: 302, Issue:1-3

    Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Airway Resistance; Analysis of Variance; Animals; Coloring Agents; Cyclic GMP; Dose-Response Relationship, Drug; Epithelium; Guinea Pigs; Histamine; Male; Methylene Blue; Muscle Contraction; Muscle Relaxation; Nitric Oxide; Purinones; Trachea

1996
Carbon monoxide enhances human neutrophil migration in a cyclic GMP-dependent way.
    Biochemical and biophysical research communications, 1996, Sep-04, Volume: 226, Issue:1

    Topics: Aminoquinolines; Carbon Monoxide; Cell Movement; Cyclic GMP; Drug Antagonism; Enzyme Activation; Guanylate Cyclase; Humans; Methylene Blue; Neutrophils

1996
Evidence for cGMP mediation of skeletal muscle arteriolar dilation to lactate.
    Journal of applied physiology (Bethesda, Md. : 1985), 1996, Volume: 81, Issue:1

    Topics: Aminoquinolines; Animals; Arterioles; Cattle; Cyclic GMP; Cyclooxygenase Inhibitors; Endothelium, Vascular; Enzyme Inhibitors; Guanylate Cyclase; Hydrogen Peroxide; Hydrogen-Ion Concentration; Image Processing, Computer-Assisted; In Vitro Techniques; Indomethacin; Lactic Acid; Male; Methylene Blue; Muscle, Skeletal; Nitric Oxide Synthase; Nitroarginine; Placenta; Pulmonary Artery; Rats; Rats, Wistar; Regional Blood Flow; Vasodilation

1996
Relaxation response to the rat stomach fundus to methylene blue.
    Research communications in molecular pathology and pharmacology, 1996, Volume: 91, Issue:2

    Topics: Animals; Atropine; Cyclic AMP; Cyclic GMP; Electric Stimulation; Gastric Fundus; Gastric Mucosa; Guanethidine; In Vitro Techniques; Male; Methylene Blue; Muscarinic Antagonists; Muscle Relaxation; Muscle, Smooth; Rats; Rats, Wistar; Serotonin; Stomach; Sympatholytics

1996
Carbon monoxide-induced relaxation of the ductus arteriosus in the lamb: evidence against the prime role of guanylyl cyclase.
    British journal of pharmacology, 1996, Volume: 118, Issue:7

    Topics: Aminoquinolines; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carbon Monoxide; Cyclic GMP; Cytochrome P-450 Enzyme System; Ductus Arteriosus; Enzyme Inhibitors; Female; Guanylate Cyclase; Indomethacin; Light; Methylene Blue; Muscle Contraction; Muscle Relaxation; Nitric Oxide Synthase; Oxygen; Pregnancy; Sheep

1996
Studies on the influence of insulin on cyclic adenosine monophosphate in human vascular smooth muscle cells: dependence on cyclic guanosine monophosphate and modulation of catecholamine effects.
    Diabetologia, 1996, Volume: 39, Issue:10

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Albuterol; Analysis of Variance; Arterioles; Cells, Cultured; Cyclic AMP; Cyclic GMP; Epinephrine; Humans; Insulin; Isoproterenol; Kinetics; Methylene Blue; Muscle, Smooth, Vascular; Norepinephrine; omega-N-Methylarginine; Propranolol; Receptors, Adrenergic, beta; Recombinant Proteins; Yohimbine

1996
Nitric oxide-donating compounds and cyclic GMP depress the spontaneous contractile activity of the isolated rabbit jejunum.
    Pharmacology, 1996, Volume: 53, Issue:2

    Topics: Analysis of Variance; Animals; Cyclic GMP; Dose-Response Relationship, Drug; Gastrointestinal Motility; Guanylate Cyclase; In Vitro Techniques; Jejunum; Methylene Blue; Muscle Contraction; Muscle, Smooth; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; Oxyhemoglobins; Rabbits

1996
Effect of cyclic GMP reduction on regional myocardial mechanics and metabolism in experimental left ventricular hypertrophy.
    Journal of cardiovascular pharmacology, 1996, Volume: 27, Issue:3

    Topics: Animals; Cyclic GMP; Dogs; Hypertrophy, Left Ventricular; Methylene Blue; Myocardial Contraction; Myocardium; Oxygen Consumption

1996
Stimulation of nitric oxide-cyclic GMP pathway by L-arginine increases the release of hepatic lipase from cultured rat hepatocytes.
    Biological & pharmaceutical bulletin, 1996, Volume: 19, Issue:10

    Topics: Alkaloids; Animals; Arginine; Carbazoles; Cyclic GMP; Enzyme Inhibitors; Indoles; Lipase; Liver; Methylene Blue; Nitric Oxide; omega-N-Methylarginine; Protein Kinase Inhibitors; Rats

1996
Evidence that guanylate cyclase is involved in modulating the resting tension and neurally-induced contraction of the guinea pig tracheal muscle.
    The West Indian medical journal, 1996, Volume: 45, Issue:3

    Topics: 1-Methyl-3-isobutylxanthine; Animals; Cyclic GMP; Electric Stimulation; Guanylate Cyclase; Guinea Pigs; Male; Methylene Blue; Muscle Contraction; Muscle Relaxation; Nitroprusside; Phosphodiesterase Inhibitors; Rest; Trachea

1996
Effect of sodium nitroprusside on compound action potential thresholds in the gerbil cochlea.
    Hearing research, 1996, Sep-15, Volume: 99, Issue:1-2

    Topics: Action Potentials; Analysis of Variance; Animals; Auditory Threshold; Blood Pressure; Cochlea; Cyclic GMP; Gerbillinae; Guanylate Cyclase; Methylene Blue; Nitroprusside; Perfusion; Perilymph; Sodium Dodecyl Sulfate; Vasodilator Agents

1996
Role of nitric oxide and cGMP system in regulation of ductus arteriosus tone in ovine fetus.
    The American journal of physiology, 1996, Volume: 271, Issue:6 Pt 2

    Topics: Animals; Cyclic GMP; Cyclooxygenase Inhibitors; Ductus Arteriosus; Endothelium, Vascular; Enzyme Inhibitors; Fetus; Immunologic Techniques; Indomethacin; Methylene Blue; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Pressure; Pulmonary Artery; Sheep; Staining and Labeling; Vasomotor System

1996
Mechanism of adrenomedullin-induced relaxation in isolated canine retinal arteries.
    Investigative ophthalmology & visual science, 1997, Volume: 38, Issue:1

    Topics: Adrenomedullin; Animals; Calcitonin Gene-Related Peptide; Cyclic AMP; Cyclic GMP; Cyclooxygenase Inhibitors; Dogs; Endothelium, Vascular; Enzyme Inhibitors; Female; Glyburide; Hypoglycemic Agents; Indomethacin; Male; Methylene Blue; Muscle Relaxation; Muscle, Smooth, Vascular; Nitroarginine; Peptides; Retinal Artery; Vasodilator Agents

1997
Effects of cGMP on L-type calcium current of adult and newborn rabbit ventricular cells.
    Cardiovascular research, 1997, Volume: 33, Issue:3

    Topics: 1-Methyl-3-isobutylxanthine; Alkaloids; Aminoquinolines; Animals; Animals, Newborn; Calcium; Calcium Channels; Carbazoles; Cells, Cultured; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Female; Glutathione; Guanylate Cyclase; Indoles; Male; Methylene Blue; Myocardium; Nitroso Compounds; Patch-Clamp Techniques; Phosphodiesterase Inhibitors; Protein Kinase Inhibitors; Rabbits; S-Nitrosoglutathione; Thionucleotides; Time Factors

1997
Carbon monoxide-induced relaxation and distribution of haem oxygenase isoenzymes in the pig urethra and lower oesophagogastric junction.
    British journal of pharmacology, 1997, Volume: 120, Issue:2

    Topics: Animals; Carbon Monoxide; Cyclic AMP; Cyclic GMP; Esophagogastric Junction; Heme Oxygenase (Decyclizing); Isoenzymes; Methylene Blue; Muscle Relaxation; Potassium Channel Blockers; Swine; Urethra

1997
[Inhibitory effect of isosorbide dinitrate on whole blood aggregation].
    Journal of cardiology, 1997, Volume: 29, Issue:4

    Topics: Angina Pectoris; Blood; Cell Aggregation; Cyclic GMP; Female; Humans; In Vitro Techniques; Isosorbide Dinitrate; Leukocytes; Male; Methylene Blue; Middle Aged; Myocardial Infarction; omega-N-Methylarginine; Platelet Aggregation; Platelet Aggregation Inhibitors; Vasodilator Agents

1997
Nitric oxide stimulates prostaglandin synthesis in cultured rabbit gastric cells.
    Prostaglandins, 1997, Volume: 53, Issue:3

    Topics: Animals; Cells, Cultured; Coloring Agents; Cyclic GMP; Dinoprostone; Enzyme Inhibitors; Epoprostenol; Gastric Mucosa; Hemoglobins; Methylene Blue; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Nitroarginine; Nitroprusside; Prostaglandins; Rabbits; Sulfhydryl Reagents

1997
Mechanism of nitric oxide-induced contraction in the rat isolated small intestine.
    British journal of pharmacology, 1997, Volume: 120, Issue:5

    Topics: Animals; Apamin; Calcium; Cyclic GMP; In Vitro Techniques; Intestine, Small; Male; Methylene Blue; Muscle Contraction; Nifedipine; Nitric Oxide; Nitroprusside; Rats; Rats, Wistar; Ryanodine

1997
The role of nitric oxide in modulating ischaemia-induced arrhythmias in rats.
    Journal of cardiovascular pharmacology, 1997, Volume: 29, Issue:4

    Topics: Analysis of Variance; Animals; Arrhythmias, Cardiac; Blood Pressure; Cyclic GMP; Disease Models, Animal; Enzyme Inhibitors; Ischemic Preconditioning, Myocardial; Male; Methylene Blue; Myocardial Ischemia; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rats; Rats, Sprague-Dawley; Sydnones; Vasodilator Agents; Ventricular Fibrillation

1997
Role of nitric oxide, cyclic GMP and superoxide in inhibition by adenosine of calcium current in rabbit atrioventricular nodal cells.
    Cardiovascular research, 1997, Volume: 34, Issue:2

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adenosine; Adrenergic beta-Agonists; Animals; Anti-Arrhythmia Agents; Atrioventricular Node; Calcium-Transporting ATPases; Cell Separation; Coloring Agents; Cyclic GMP; Isoproterenol; Methylene Blue; Nitric Oxide; Patch-Clamp Techniques; Rabbits; Superoxides; Xanthine Oxidase

1997
Local inotropic stimulation by methylene blue does not improve mechanical dysfunction due to myocardial stunning.
    Research in experimental medicine. Zeitschrift fur die gesamte experimentelle Medizin einschliesslich experimenteller Chirurgie, 1997, Volume: 197, Issue:1

    Topics: Animals; Coloring Agents; Coronary Vessels; Cyclic GMP; Diastole; Dogs; Female; Hemodynamics; Male; Methylene Blue; Myocardial Contraction; Myocardial Stunning; Myocardium; Oxygen Consumption

1997
Heterogeneity in the vasorelaxing effect of nicorandil on dog epicardial coronary arteries: comparison with other NO donors.
    Journal of cardiovascular pharmacology, 1997, Volume: 29, Issue:6

    Topics: Animals; Atrial Natriuretic Factor; Benzopyrans; Coronary Vessels; Cromakalim; Cyclic GMP; Dogs; Female; Glyburide; In Vitro Techniques; Male; Methylene Blue; Molsidomine; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Niacinamide; Nicorandil; Nitric Oxide; Nitroglycerin; Nitroprusside; Oxyhemoglobins; Pyrroles; Vasodilator Agents

1997
Carbon monoxide inhibits hypoxic pulmonary vasoconstriction in rats by a cGMP-independent mechanism.
    Pflugers Archiv : European journal of physiology, 1997, Volume: 434, Issue:6

    Topics: Animals; Carbon Monoxide; Cyclic GMP; Enzyme Inhibitors; Female; Guanylate Cyclase; Hypoxia; In Vitro Techniques; Methylene Blue; Nitric Oxide Synthase; Nitroarginine; Pulmonary Artery; Pulmonary Circulation; Rats; Rats, Wistar; Solubility; Vasoconstriction

1997
Ex vivo study of the increased sensitivity to NO of endothelium-denuded thoracic aortas isolated from dietary magnesium-deficient rats.
    Magnesium research, 1997, Volume: 10, Issue:1

    Topics: Animals; Aorta, Thoracic; Cromakalim; Cyclic GMP; Diet; Endothelium, Vascular; In Vitro Techniques; Magnesium Deficiency; Male; Methylene Blue; Muscle Relaxation; Nitric Oxide; Nitroprusside; Potassium Channel Blockers; Potassium Channels; Rats; Rats, Wistar

1997
The novel role of 3',5'-guanosine monophosphate (cGMP) on the differentiation of trophoblasts: comparison with the effects of 3',5'-adenosine monophosphate (cAMP).
    Early pregnancy : biology and medicine : the official journal of the Society for the Investigation of Early Pregnancy, 1996, Volume: 2, Issue:4

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Antibodies; Cell Count; Cell Differentiation; Cell Division; Cells, Cultured; Chorionic Gonadotropin; Cyclic AMP; Cyclic GMP; DNA; Dose-Response Relationship, Drug; Female; Humans; Immunohistochemistry; Methylene Blue; Nitroprusside; Pregnancy; Thymidine; Tritium; Trophoblasts

1996
Methylene blue induces ongoing activity in rat cutaneous primary afferents and depolarization of DRG neurons via a photosensitive mechanism.
    Naunyn-Schmiedeberg's archives of pharmacology, 1997, Volume: 356, Issue:5

    Topics: Action Potentials; Animals; Cyclic GMP; Dermatitis, Phototoxic; Ganglia, Spinal; Male; Methylene Blue; Neurons, Afferent; Rats; Rats, Wistar; Second Messenger Systems; Skin

1997
Potentiation and inhibition of fMLP-activated exocytosis in neutrophils by exogenous nitric oxide.
    Immunopharmacology, 1997, Volume: 37, Issue:2-3

    Topics: Aminoquinolines; Animals; Calcium; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Drug Synergism; Enzyme Inhibitors; Exocytosis; Female; Methylene Blue; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Nitric Oxide; Peritoneal Cavity; Rabbits; Stimulation, Chemical

1997
Nitric oxide-induced ciliary muscle relaxation during contraction with endothelin-1 is mediated through elevation of cyclic GMP.
    Current eye research, 1997, Volume: 16, Issue:12

    Topics: 1-Methyl-3-isobutylxanthine; Animals; Cattle; Ciliary Body; Cyclic GMP; Drug Combinations; Endothelin-1; Guanylate Cyclase; In Vitro Techniques; Methylene Blue; Muscle Contraction; Muscle Relaxation; Nitric Oxide; Nitroprusside; Phosphodiesterase Inhibitors

1997
Effect of atrial natriuretic peptide on sodium-glucose cotransport in the rat small intestine.
    Peptides, 1997, Volume: 18, Issue:10

    Topics: Animals; Atrial Natriuretic Factor; Biological Transport; Cyclic GMP; Electric Conductivity; Intestine, Small; Male; Methylene Blue; Monosaccharide Transport Proteins; Nitric Oxide; Patch-Clamp Techniques; Phlorhizin; Rats; Rats, Wistar; Sodium

1997
Nitric oxide and cyclic GMP regulate retinal patterning in the optic lobe of Drosophila.
    Neuron, 1998, Volume: 20, Issue:1

    Topics: Afferent Pathways; Animals; Axons; Cyclic GMP; Drosophila; Enzyme Inhibitors; Ganglia, Sensory; Guanylate Cyclase; Metamorphosis, Biological; Methylene Blue; NADPH Dehydrogenase; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Optic Lobe, Nonmammalian; Optic Nerve; Photoreceptor Cells, Invertebrate; Retina; Synaptic Transmission

1998
The deactivation of soluble guanylyl cyclase by redox-active agents.
    Archives of biochemistry and biophysics, 1998, Mar-01, Volume: 351, Issue:1

    Topics: Animals; Cattle; Cyclic GMP; Enzyme Activation; Ferricyanides; Guanylate Cyclase; Heme; Kinetics; Methylene Blue; Nitrates; Nitric Oxide; Oxidation-Reduction; Solubility

1998
The role of cGMP in the relaxation to nitric oxide donors in airway smooth muscle.
    European journal of pharmacology, 1998, Jan-12, Volume: 341, Issue:2-3

    Topics: Aminoquinolines; Animals; Antidotes; Cyclic GMP; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Guanylate Cyclase; Isometric Contraction; Methylene Blue; Muscle Relaxation; Muscle, Smooth; Nitric Oxide; Swine

1998
Pranidipine, a new 1,4-dihydropyridine calcium channel blocker, enhances cyclic GMP-independent nitric oxide-induced relaxation of the rat aorta.
    Molecular and cellular biochemistry, 1998, Volume: 178, Issue:1-2

    Topics: Amlodipine; Animals; Aorta; Calcium Channel Blockers; Cyclic GMP; Dihydropyridines; Dimethyl Sulfoxide; Dinoprost; Endothelium, Vascular; Indomethacin; Male; Methylene Blue; Muscle, Smooth, Vascular; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Wistar; Vasodilation; Vasodilator Agents

1998
Halothane attenuates nitric oxide relaxation of rat aortas by competition for the nitric oxide receptor site on soluble guanylyl cyclase.
    European journal of pharmacology, 1998, Jan-26, Volume: 342, Issue:2-3

    Topics: Aminoquinolines; Anesthetics, Inhalation; Animals; Aorta, Thoracic; Binding, Competitive; Cyclic GMP; Enzyme Inhibitors; Guanylate Cyclase; Halothane; In Vitro Techniques; Male; Methylene Blue; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; Nitroglycerin; Rats; Rats, Sprague-Dawley; Vasodilator Agents

1998
Rapid development of nitric oxide-induced hyperalgesia depends on an alternate to the cGMP-mediated pathway in the rat neuropathic pain model.
    Brain research, 1998, May-11, Volume: 792, Issue:2

    Topics: Animals; Antidotes; Cyclic GMP; Disease Models, Animal; Dizocilpine Maleate; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Hemoglobins; Hot Temperature; Hyperalgesia; Ligation; Male; Methylene Blue; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitroso Compounds; Pain; Rats; Rats, Sprague-Dawley; Sciatic Nerve; Spinal Cord

1998
Depolarization of isolated brain nerve endings by nitric oxide donors: membrane mechanisms.
    Biochemistry. Biokhimiia, 1998, Volume: 63, Issue:6

    Topics: Animals; Brain; Cyclic GMP; Enzyme Inhibitors; Guanylate Cyclase; In Vitro Techniques; Kinetics; Male; Membrane Potentials; Methylene Blue; Nerve Endings; Nitric Oxide Donors; Onium Compounds; Organophosphorus Compounds; Potassium Channels; Rats; Rats, Wistar; Rubidium; Sodium Channel Blockers; Synaptosomes; Tissue Distribution

1998
cGMP-independent mechanism of airway smooth muscle relaxation induced by S-nitrosoglutathione.
    The American journal of physiology, 1998, Volume: 275, Issue:2

    Topics: Acetylcholine; Animals; Cyclic AMP; Cyclic GMP; Cytosol; Dithiothreitol; Dogs; Enzyme Inhibitors; Female; Glutathione; Guanylate Cyclase; In Vitro Techniques; Isometric Contraction; Male; Methylene Blue; Muscle Relaxation; Muscle, Smooth; Nitroso Compounds; S-Nitrosoglutathione; Trachea

1998
Relaxant effects of sodium nitroprusside and NONOates in rabbit basilar artery.
    Pharmacology, 1998, Volume: 57, Issue:2

    Topics: Acetylcholine; Animals; Basilar Artery; Cyclic GMP; Diethylamines; Endothelium, Vascular; Histamine; Male; Methylene Blue; Nitric Oxide; Nitroprusside; Polyamines; Rabbits; Spermine; Structure-Activity Relationship; Uridine Triphosphate; Vasoconstriction; Vasodilation; Vasodilator Agents

1998
Positive functional effects of milrinone and methylene blue are not additive in control and hypertrophic canine hearts.
    The Journal of surgical research, 1998, Volume: 77, Issue:1

    Topics: Animals; Cyclic AMP; Cyclic GMP; Dogs; Drug Combinations; Drug Synergism; Enzyme Inhibitors; Guanylate Cyclase; Heart; Hemodynamics; Hypertrophy, Left Ventricular; Methylene Blue; Milrinone; Myocardium; Oxygen Consumption; Phosphodiesterase Inhibitors; Pyridones; Reference Values

1998
Cyclic GMP-dependent but G-kinase-independent inhibition of Ca2+-dependent Cl- currents by NO donors in cat tracheal smooth muscle.
    The Journal of physiology, 1998, Sep-15, Volume: 511 ( Pt 3)

    Topics: Animals; Anthracenes; Caffeine; Calcium; Carbachol; Cats; Chloride Channels; Chlorides; Cyclic GMP; Dibutyryl Cyclic GMP; Enzyme Inhibitors; Female; GTP-Binding Proteins; Male; Membrane Potentials; Methylene Blue; Muscarinic Agonists; Muscle, Smooth; Nitric Oxide Donors; Patch-Clamp Techniques; Penicillamine; Phosphodiesterase Inhibitors; Receptor, Muscarinic M3; Receptors, Muscarinic; Ryanodine; Thionucleotides; Trachea; Zinc

1998
Sodium nitroprusside-induced cGMP-independent vasodilator responses in the perfused rabbit ovarian vascular bed.
    Pharmacological research, 1998, Volume: 38, Issue:5

    Topics: Aminoquinolines; Animals; Carbachol; Cyclic GMP; Endothelium, Vascular; Enzyme Inhibitors; Female; Guanylate Cyclase; In Vitro Techniques; Methylene Blue; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Nitroarginine; Nitroprusside; Ovary; Rabbits; Vasodilation

1998
Propofol-induced relaxation of rat mesenteric arteries: evidence for a cyclic GMP-mediated mechanism.
    Journal of cardiovascular pharmacology, 1998, Volume: 32, Issue:5

    Topics: Animals; Calcium; Cyclic GMP; Dose-Response Relationship, Drug; Male; Mesenteric Arteries; Methylene Blue; Propofol; Rats; Rats, Inbred WKY; Vasodilation

1998
Nitric oxide relaxes human myometrium by a cGMP-independent mechanism.
    The American journal of physiology, 1998, Volume: 275, Issue:6

    Topics: Aminoquinolines; Charybdotoxin; Cyclic GMP; Cysteine; Enzyme Inhibitors; Female; Guanylate Cyclase; Humans; Methylene Blue; Myometrium; Nitric Oxide; Nitric Oxide Donors; Nitroso Compounds; S-Nitrosothiols; Uterine Contraction

1998
Angiotensin IV receptor-mediated activation of lung endothelial NOS is associated with vasorelaxation.
    The American journal of physiology, 1998, Volume: 275, Issue:6

    Topics: Aminopeptidases; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Cells, Cultured; Cyclic GMP; Endothelium, Vascular; Enzyme Activation; Glutamyl Aminopeptidase; Indomethacin; Methionyl Aminopeptidases; Methylene Blue; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Pulmonary Artery; Receptors, Angiotensin; Swine; Vasodilation

1998
Comparison of two soluble guanylyl cyclase inhibitors, methylene blue and ODQ, on sodium nitroprusside-induced relaxation in guinea-pig trachea.
    British journal of pharmacology, 1998, Volume: 125, Issue:6

    Topics: Animals; Cyclic GMP; Drug Interactions; Enzyme Inhibitors; Guanylate Cyclase; Guinea Pigs; Methylene Blue; Mice; Muscle Relaxation; Muscle, Smooth; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitroprusside; Oxadiazoles; Quinoxalines; Signal Transduction; Solubility; Trachea; Vasodilator Agents

1998
Role of nitric oxide and cGMP in human septic serum-induced depression of cardiac myocyte contractility.
    The American journal of physiology, 1999, Volume: 276, Issue:1

    Topics: Animals; Arginine; Blood Physiological Phenomena; Cyclic GMP; Drug Combinations; Enzyme Inhibitors; Humans; Interleukin-1; Methylene Blue; Myocardial Contraction; Myocardium; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Nucleotides, Cyclic; omega-N-Methylarginine; Rats; Shock, Septic; Tumor Necrosis Factor-alpha

1999
Nitric oxide stimulates cyclic guanosine monophosphate production and electrogenic secretion in Caco-2 colonocytes.
    Clinical science (London, England : 1979), 1999, Volume: 96, Issue:2

    Topics: Arginine; Caco-2 Cells; Cyclic GMP; Cystamine; Enzyme Inhibitors; Humans; Inflammatory Bowel Diseases; Intestinal Mucosa; Ion Transport; Isomerism; Methylene Blue; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitrites; Nitroprusside

1999
Positive inotropy due to lowering cyclic GMP is also mediated by increases in cyclic AMP in control and hypertrophic hearts.
    Canadian journal of physiology and pharmacology, 1998, Volume: 76, Issue:6

    Topics: Animals; Cardiotonic Agents; Cyclic AMP; Cyclic GMP; Dogs; Enzyme Inhibitors; Guanylate Cyclase; Heart; Hypertrophy, Left Ventricular; In Vitro Techniques; Isoproterenol; Methylene Blue; Myocardium; Oxygen Consumption

1998
Cardioprotective effect of angiotensin-converting enzyme inhibition against hypoxia/reoxygenation injury in cultured rat cardiac myocytes.
    Circulation, 1999, Feb-16, Volume: 99, Issue:6

    Topics: Adrenergic beta-Antagonists; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Bradykinin; Cell Hypoxia; Cells, Cultured; Cilazapril; Creatine Kinase; Cyclic GMP; Cyclooxygenase Inhibitors; Enzyme Inhibitors; Guanidines; Indomethacin; Methylene Blue; Muscle Fibers, Skeletal; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardium; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Oxygen; Rats; Rats, Wistar; Staurosporine; Tetrazoles

1999
Role of nitric oxide production in carbachol-induced negative chronotropy in cultured rat ventricular myocytes.
    European journal of pharmacology, 1999, Jan-29, Volume: 366, Issue:1

    Topics: Animals; Animals, Newborn; Atropine; Carbachol; Cells, Cultured; Cyclic GMP; Dose-Response Relationship, Drug; Enzyme Inhibitors; Guanylate Cyclase; Heart Ventricles; Methylene Blue; Myocardial Contraction; Myocardium; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Nitrites; omega-N-Methylarginine; Oxadiazoles; Quinoxalines; Rats; Rats, Wistar; Signal Transduction

1999
[The effect of NO-like relaxing factor on vascular reactivity in tourniquet shock rat].
    Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology, 1997, Volume: 13, Issue:3

    Topics: Animals; Cyclic GMP; Guanylate Cyclase; Male; Methylene Blue; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Rats; Rats, Wistar; Shock; Tourniquets; Vasoconstriction

1997
Activation of nitric oxide synthase (NOS3) by mechanical activity alters contractile activity in a Ca2+-independent manner in cardiac myocytes: role of troponin I phosphorylation.
    Biochemical and biophysical research communications, 1999, Mar-16, Volume: 256, Issue:2

    Topics: Actin Cytoskeleton; Alkaloids; Animals; Calcium; Carbazoles; Cardiac Pacing, Artificial; Cell Size; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Enzyme Activation; Heart Ventricles; In Vitro Techniques; Indoles; Male; Methylene Blue; Myocardial Contraction; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Nitroarginine; Phosphorylation; Rats; Rats, Sprague-Dawley; Troponin I; Ventricular Function

1999
Possible novel mechanism for bitter taste mediated through cGMP.
    Journal of neurophysiology, 1999, Volume: 81, Issue:4

    Topics: Aminoquinolines; Animals; Caffeine; Cyclic AMP; Cyclic GMP; Enzyme Inhibitors; Glycine Agents; Methylene Blue; Mice; Nitro Compounds; Nitroprusside; Oxadiazoles; Phosphodiesterase Inhibitors; Quaternary Ammonium Compounds; Quinoxalines; Signal Transduction; Strychnine; Sulfhydryl Reagents; Taste; Theophylline

1999
Intracerebroventricularly injected L-arginine-induced vasopressin release is mediated by cGMP in rats.
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1998, Volume: 19, Issue:5

    Topics: Animals; Arginine; Arginine Vasopressin; Cyclic GMP; Guanylate Cyclase; Injections, Intraventricular; Male; Methylene Blue; Rats; Rats, Sprague-Dawley

1998
Cyclic GMP regulates cromakalim-induced relaxation in the rat aortic smooth muscle: role of cyclic GMP in K(ATP)-channels.
    Life sciences, 1999, Volume: 64, Issue:26

    Topics: Adenosine Triphosphate; Animals; Aorta, Thoracic; Apamin; Calcium; Charybdotoxin; Cromakalim; Cyclic GMP; Endothelium, Vascular; Glyburide; In Vitro Techniques; Male; Methylene Blue; Molsidomine; Muscle Relaxation; Muscle, Smooth, Vascular; Nitroprusside; Potassium Channel Blockers; Potassium Channels; Rats; Rats, Inbred WKY

1999
Methylene blue, a soluble guanylyl cyclase inhibitor, reduces the sevoflurane minimum alveolar anesthetic concentration and decreases the brain cyclic guanosine monophosphate content in rats.
    Anesthesia and analgesia, 1999, Volume: 89, Issue:2

    Topics: Anesthetics, Inhalation; Animals; Brain; Cyclic GMP; Dose-Response Relationship, Drug; Enzyme Inhibitors; Guanylate Cyclase; In Vitro Techniques; Injections, Intraventricular; Methyl Ethers; Methylene Blue; Nitric Oxide; Rats; Rats, Sprague-Dawley; Sevoflurane

1999
Pacing-induced cardiac failure of hypertrophic hearts: effects of cyclic GMP reduction.
    The Journal of surgical research, 1999, Volume: 86, Issue:1

    Topics: Animals; Cardiac Output, Low; Cardiac Pacing, Artificial; Cyclic GMP; Dogs; Hypertrophy, Left Ventricular; Methylene Blue; Myocardial Contraction; Myocardium; Reference Values

1999
Central control of blood pressure by nitrergic mechanisms in organum vasculosum laminae terminalis of rat brain.
    British journal of pharmacology, 1999, Volume: 127, Issue:6

    Topics: Animals; Arginine; Blood Pressure; Brain; Cyclic GMP; Enzyme Inhibitors; Guanylate Cyclase; Hydroxylamine; Male; Methylene Blue; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitroprusside; Rats; Rats, Sprague-Dawley; Sodium Azide; Spinal Cord Injuries

1999
Effects of L-arginine on the afferent resting activity in the cephalopod statocyst.
    Brain research, 1999, Oct-16, Volume: 845, Issue:1

    Topics: Action Potentials; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Arginine; Cyclic AMP; Cyclic GMP; Cystamine; DDT; Decapodiformes; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Guanylate Cyclase; Hair Cells, Vestibular; Imines; Immunosuppressive Agents; Male; Methylene Blue; Mollusca; NADP; NG-Nitroarginine Methyl Ester; Niacin; Nitric Oxide; Nitroarginine; Oxadiazoles; Postural Balance; Quinoxalines; Sodium Chloride

1999
Endothelium-derived relaxing factor: discovery, early studies, and identification as nitric oxide.
    Bioscience reports, 1999, Volume: 19, Issue:4

    Topics: Acetylcholine; Animals; Aorta, Thoracic; Cyclic GMP; Endothelium, Vascular; Hemoglobins; Methylene Blue; Nitric Oxide; Rabbits; Time Factors; Vasodilator Agents

1999
Mechanisms for regulation of fluid shear stress response in circulating leukocytes.
    Circulation research, 2000, Jan-07, Volume: 86, Issue:1

    Topics: Aminoquinolines; Animals; Cell Adhesion; Cyclic GMP; Humans; In Vitro Techniques; Leukocytes; Methylene Blue; Mice; Mice, Inbred C57BL; Mice, Knockout; N-Formylmethionine Leucyl-Phenylalanine; Nitric Oxide Donors; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Platelet Activating Factor; Rats; Rats, Wistar; Stress, Physiological

2000
[NO production through catalase and myoglobin, hemeproteins, in vascular smooth muscle].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1999, Volume: 114 Suppl 1

    Topics: Animals; Aorta; Azides; Catalase; Cyclic GMP; Guinea Pigs; Hemeproteins; Hydroxylamine; In Vitro Techniques; Methylene Blue; Muscle, Smooth, Vascular; Myoglobin; Nitric Oxide; Nitrites; omega-N-Methylarginine; Rats; Vasodilation

1999
Does TAME induced contraction involve an endothelium dependent nitric oxide-cyclic GMP mediated pathway?
    Indian journal of experimental biology, 1999, Volume: 37, Issue:4

    Topics: Animals; Bufonidae; Cyclic GMP; Endothelium, Vascular; Ileum; In Vitro Techniques; Methylene Blue; Muscle Contraction; Muscle, Smooth; NG-Nitroarginine Methyl Ester; Nitric Oxide; Tosylarginine Methyl Ester

1999
Decreased endothelium-dependent vascular relaxation during reduction of uterine perfusion pressure in pregnant rat.
    Hypertension (Dallas, Tex. : 1979), 2000, Volume: 35, Issue:1 Pt 2

    Topics: Acetylcholine; Animals; Aorta; Blood Pressure; Cyclic GMP; Endothelium, Vascular; Enzyme Inhibitors; Female; Hypertension; Methylene Blue; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitroprusside; Phenylephrine; Pregnancy; Pregnancy Complications, Cardiovascular; Rats; Rats, Sprague-Dawley; Uterus; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents

2000
Role of the nitric oxide-cGMP system in the regulation of ductus arteriosus patency in fetal rats.
    The Journal of veterinary medical science, 1999, Volume: 61, Issue:12

    Topics: Animals; Aorta, Thoracic; Cesarean Section; Cyclic GMP; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Ductus Arteriosus; Enzyme Inhibitors; Female; Fetus; Indomethacin; Methylene Blue; NG-Nitroarginine Methyl Ester; Nitric Oxide; Pregnancy; Pulmonary Artery; Rats; Rats, Wistar

1999
Vasodilatory actions of the dietary peptide carnosine.
    Nutrition (Burbank, Los Angeles County, Calif.), 2000, Volume: 16, Issue:3

    Topics: Animals; Aorta, Thoracic; Carnosine; Cyclic GMP; Enzyme Inhibitors; Guanylate Cyclase; Male; Methylene Blue; Phenylephrine; Rats; Rats, Sprague-Dawley; Vasodilation

2000
delta-opioid receptors and nitric oxide mediate the analgesic effect of Crotalus durissus terrificus snake venom.
    European journal of pharmacology, 2000, Mar-10, Volume: 391, Issue:1-2

    Topics: Analgesics, Non-Narcotic; Animals; Arginine; Carrageenan; Crotalid Venoms; Cyclic GMP; Edema; Enzyme Inhibitors; Hyperalgesia; Male; Methylene Blue; Motor Activity; Narcotic Antagonists; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Rats; Rats, Wistar; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu

2000
Actions of L-NAME and methylene blue on the hypotensive effects of clonidine and rilmenidine in the anesthetized rat.
    Journal of cardiovascular pharmacology, 2000, Volume: 35, Issue:5

    Topics: Anesthesia; Animals; Antihypertensive Agents; Blood Pressure; Clonidine; Cyclic GMP; Drug Interactions; Enzyme Inhibitors; Hypotension; Male; Methylene Blue; NG-Nitroarginine Methyl Ester; Nitric Oxide; Oxazoles; Rats; Rats, Wistar; Rilmenidine

2000
The effect of cyclic GMP on rabbit corporal smooth muscle tone and its modulation by cyclo-oxygenase products.
    Prostaglandins, leukotrienes, and essential fatty acids, 2000, Volume: 62, Issue:3

    Topics: Acetylcholine; Aminoquinolines; Animals; Cyclic GMP; Enzyme Inhibitors; Guanylate Cyclase; Indomethacin; Male; Methylene Blue; Muscle Relaxation; Muscle Tonus; Muscle, Smooth; Penis; Prostaglandin-Endoperoxide Synthases; Rabbits

2000
The role of nitric oxide, K(+)(ATP) channels, and cGMP in the preconditioning response of the rabbit.
    The Journal of surgical research, 2000, Volume: 92, Issue:1

    Topics: Action Potentials; Adenosine Triphosphate; Animals; Arginine; Coronary Circulation; Cyclic GMP; Enzyme Inhibitors; In Vitro Techniques; Ischemic Preconditioning; Male; Methylene Blue; Muscle Fibers, Skeletal; Myocardial Infarction; Myocardial Ischemia; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide; Potassium Channels; Rabbits

2000
L-NAME causes antinociception by stimulation of the arginine-NO-cGMP pathway.
    Mediators of inflammation, 2000, Volume: 9, Issue:1

    Topics: Analgesics; Animals; Arginine; Carrageenan; Cyclic GMP; Dinoprostone; Hyperalgesia; Male; Methylene Blue; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide; omega-N-Methylarginine; Oxadiazoles; Phosphodiesterase Inhibitors; Phthalazines; Quinoxalines; Rats; Rats, Wistar; Signal Transduction

2000
Shortening of cardiac action potentials in endotoxic shock in guinea pigs is caused by an increase in nitric oxide activity and activation of the adenosine triphosphate-sensitive potassium channel.
    Critical care medicine, 2000, Volume: 28, Issue:6

    Topics: Action Potentials; Adenosine Triphosphate; Animals; Cyclic GMP; Enzyme Inhibitors; Glyburide; Guanidines; Guinea Pigs; Lipopolysaccharides; Methylene Blue; NG-Nitroarginine Methyl Ester; Nitric Oxide; Papillary Muscles; Potassium Channels; Shock, Septic; Time Factors

2000
Participation of the components of L-arginine/nitric oxide/cGMP cascade by chemically-induced abdominal constriction in the mouse.
    Life sciences, 2000, Volume: 67, Issue:10

    Topics: Abdominal Pain; Analgesics; Animals; Arginine; Benzoquinones; Cyclic GMP; Dose-Response Relationship, Drug; Enzyme Inhibitors; Guanylate Cyclase; Male; Methylene Blue; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Pain Measurement

2000
Effects of sigma receptor agonists on the impairment of spontaneous alternation behavior and decrease of cyclic GMP level induced by nitric oxide synthase inhibitors in mice.
    Neuropharmacology, 2000, Volume: 39, Issue:12

    Topics: Analgesics, Opioid; Animals; Anti-Anxiety Agents; Antipsychotic Agents; Behavior, Animal; Brain Chemistry; Cyclic GMP; Enzyme Inhibitors; Guanidines; Indazoles; Male; Methylene Blue; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Pentazocine; Phenazocine; Pyrimidines; Receptors, sigma

2000
Inhibitory effect of cyclic guanosine 3',5'-monophosphate (cGMP) on the afferent resting activity in the cephalopod statocyst.
    Brain research, 2000, Oct-13, Volume: 880, Issue:1-2

    Topics: Afferent Pathways; Animals; Cyclic GMP; Cystamine; Decapodiformes; Dibutyryl Cyclic GMP; Dideoxyadenosine; Enzyme Inhibitors; Imines; Methylene Blue; Mollusca; NG-Nitroarginine Methyl Ester; Niacin; Nitroarginine; Oxadiazoles; Quinoxalines; Sense Organs

2000
Nitric oxide is an excitatory modulator in the rostral ventrolateral medulla in rats.
    American journal of hypertension, 2000, Volume: 13, Issue:10

    Topics: Animals; Cyclic GMP; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Guanylate Cyclase; Male; Medulla Oblongata; Methylene Blue; Neurons; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitroarginine; Nitroprusside; Oligonucleotides, Antisense; Prodrugs; Proto-Oncogene Proteins c-fos; Rats; Rats, Wistar; Receptors, Glutamate; Solubility

2000
Effects of nitric oxide donors on Ca2+-dependent [14C]GABA release from brain synaptosomes: the role of SH-groups.
    Biochemistry. Biokhimiia, 2000, Volume: 65, Issue:9

    Topics: Animals; Brain; Calcium; Carbon Isotopes; Cyclic GMP; Cysteine; Dibutyryl Cyclic GMP; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Ethylmaleimide; gamma-Aminobutyric Acid; Guanylate Cyclase; Hydroxylamine; Kinetics; Male; Methylene Blue; Nitric Oxide Donors; Nitroprusside; Nitroso Compounds; Potassium; Rats; Rats, Wistar; S-Nitrosothiols; src Homology Domains; Sulfhydryl Reagents; Synaptosomes; Time Factors

2000
Mesenteric hyporesponsiveness in cirrhotic rats with ascites: role of cGMP and K+ channels.
    Clinical science (London, England : 1979), 2000, Volume: 99, Issue:5

    Topics: Animals; Cyclic GMP; Enzyme Inhibitors; Liver Cirrhosis, Experimental; Male; Mesenteric Artery, Superior; Methoxamine; Methylene Blue; Nitroarginine; Potassium Channels; Pressoreceptors; Rats; Rats, Sprague-Dawley; Tetraethylammonium; Vasoconstriction; Vasoconstrictor Agents

2000
Role of heme oxygenase-carbon monoxide pathway in pathogenesis of cirrhotic cardiomyopathy in the rat.
    American journal of physiology. Gastrointestinal and liver physiology, 2001, Volume: 280, Issue:1

    Topics: Animals; Blotting, Western; Carbon Monoxide; Cardiomyopathies; Cardiotonic Agents; Cyclic GMP; DNA Primers; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Guanylate Cyclase; Heat-Shock Proteins; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; Isoproterenol; Liver Cirrhosis; Male; Methylene Blue; Myocardial Contraction; Papillary Muscles; Protoporphyrins; Rats; Rats, Sprague-Dawley; RNA, Messenger

2001
Sodium nitroprusside increases pacemaker rhythm of sinoatrial nodes via nitric oxide-cGMP pathway.
    The Chinese journal of physiology, 2000, Sep-30, Volume: 43, Issue:3

    Topics: Action Potentials; Animals; Cyclic GMP; Electrophysiology; Enzyme Inhibitors; Guinea Pigs; In Vitro Techniques; Male; Methylene Blue; Nitric Oxide; Nitroprusside; Papillary Muscles; Periodicity; Potassium; Potassium Channels; Sinoatrial Node; Vasodilator Agents

2000
Cyclic GMP-dependent relaxation of isolated rat renal glomeruli induced by extracellular ATP.
    The Journal of physiology, 2001, Jan-01, Volume: 530, Issue:Pt 1

    Topics: Adenosine Triphosphate; Animals; Citrulline; Cyclic GMP; Enzyme Inhibitors; Extracellular Space; Guanylate Cyclase; In Vitro Techniques; Inulin; Kidney Glomerulus; Male; Methylene Blue; Muscle Relaxation; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Nitroarginine; Rats; Rats, Wistar; Receptors, Purinergic P2

2001
Polyamines, NO and cGMP mediate stimulation of DNA synthesis by tumor necrosis factor and lipopolysaccharide in chick embryo cardiomyocytes.
    Cardiovascular research, 2001, Feb-01, Volume: 49, Issue:2

    Topics: Alkaloids; Aminoquinolines; Animals; Carbazoles; Cells, Cultured; Chick Embryo; Cyclic GMP; DNA; Eflornithine; Enzyme Activation; Enzyme Inhibitors; Guanylate Cyclase; Indoles; Lipopolysaccharides; Methylene Blue; Myocardium; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Polyamines; Protein Kinase Inhibitors; Stimulation, Chemical; Tumor Necrosis Factor-alpha

2001
Modulation of Kv3 potassium channels expressed in CHO cells by a nitric oxide-activated phosphatase.
    The Journal of physiology, 2001, Feb-01, Volume: 530, Issue:Pt 3

    Topics: Alkaloids; Animals; Carbazoles; CHO Cells; Cricetinae; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Enzyme Inhibitors; Guanylate Cyclase; Indoles; Membrane Potentials; Methylene Blue; Neuropeptides; Nitric Oxide; Nitric Oxide Donors; Okadaic Acid; Patch-Clamp Techniques; Phosphoprotein Phosphatases; Potassium Channels; Potassium Channels, Voltage-Gated; Protein Kinases; Protein Phosphatase 2; Recombinant Proteins; Shaw Potassium Channels; Transfection

2001
Inhibitory effects of nicorandil on rat mesangial cell proliferation via the protein kinase G pathway.
    Nephron, 2001, Volume: 87, Issue:3

    Topics: Alkaloids; Animals; Carbazoles; Cell Division; Cells, Cultured; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Glomerular Mesangium; Guanylate Cyclase; Indoles; Male; Methylene Blue; Nicorandil; Potassium Channel Blockers; Potassium Channels; Rats; Rats, Wistar; Signal Transduction; Thymidine

2001
Nitric oxide decreases lung liquid production via guanosine 3',5'-cyclic monophosphate.
    American journal of physiology. Lung cellular and molecular physiology, 2001, Volume: 280, Issue:5

    Topics: 3',5'-Cyclic-GMP Phosphodiesterases; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Blood Gas Analysis; Blood Pressure; Cyclic GMP; Drug Administration Routes; Enzyme Inhibitors; Fetus; Guanylate Cyclase; Lung; Methylene Blue; Nitric Oxide; Pulmonary Circulation; Purinones; Sheep; Vascular Resistance

2001
Early suppression of striatal cyclic GMP may predetermine the induction and severity of chronic haloperidol-induced vacous chewing movements.
    Metabolic brain disease, 2000, Volume: 15, Issue:4

    Topics: Animals; Chronic Disease; Corpus Striatum; Cyclic GMP; Dopamine Antagonists; Dyskinesia, Drug-Induced; Enzyme Inhibitors; Extrapyramidal Tracts; Haloperidol; Male; Mastication; Methylene Blue; Motor Activity; Nitric Oxide; Rats; Rats, Sprague-Dawley

2000
Sildenafil-induced peripheral analgesia and activation of the nitric oxide-cyclic GMP pathway.
    Brain research, 2001, Aug-03, Volume: 909, Issue:1-2

    Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Acetic Acid; Analgesia; Animals; Arginine; Carrageenan; Central Nervous System; Cyclic GMP; Cyclic Nucleotide Phosphodiesterases, Type 5; Dose-Response Relationship, Drug; Female; Hyperalgesia; Male; Methylene Blue; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitroprusside; Nociceptors; Pain; Pain Measurement; Pain Threshold; Peripheral Nervous System; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Piperazines; Purines; Signal Transduction; Sildenafil Citrate; Sulfones

2001
Nitric oxide/cGMP-induced inhibition of calcium and chloride currents in retinal pericytes.
    Microvascular research, 2001, Volume: 62, Issue:2

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Calcium; Chlorides; Cyclic GMP; Enzyme Inhibitors; Ion Channels; Methylene Blue; Nifedipine; Nitric Oxide; Nitroprusside; Patch-Clamp Techniques; Pericytes; Rats; Retinal Vessels; Vasodilator Agents

2001
A xanthine-based KMUP-1 with cyclic GMP enhancing and K(+) channels opening activities in rat aortic smooth muscle.
    British journal of pharmacology, 2001, Volume: 134, Issue:2

    Topics: Acetylcholine; Adenylyl Cyclases; Animals; Aorta; Aorta, Thoracic; Blood Pressure; Cells, Cultured; Cromakalim; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Inhibitors; Glyburide; Heart Rate; In Vitro Techniques; Methylene Blue; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitroprusside; Oxadiazoles; Phosphoric Diester Hydrolases; Piperidines; Potassium Channels; Quinoxalines; Rats; Rats, Wistar; Solubility; Vasodilation; Vasodilator Agents; Xanthine; Xanthines

2001
Transplacental exposure to methylene blue initiates teratogenesis in the mouse: preliminary evidence for a mechanistic implication of cyclic GMP pathway disruption.
    Teratology, 2001, Volume: 64, Issue:4

    Topics: Animals; Bone and Bones; Cyclic GMP; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Maternal Exposure; Methylene Blue; Mice; Mice, Inbred ICR; Neural Tube Defects; Phosphodiesterase Inhibitors; Placenta; Purinones; Teratogens; Time Factors

2001
Sildenafil inhibits agonist-evoked rat uterine contractility: influence of guanylyl cyclase inhibition.
    European journal of pharmacology, 2001, Oct-12, Volume: 428, Issue:3

    Topics: Acetylcholine; Animals; Cyclic GMP; Dinoprostone; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Guanylate Cyclase; In Vitro Techniques; Methylene Blue; Muscle Contraction; Oxytocics; Oxytocin; Phosphodiesterase Inhibitors; Piperazines; Purines; Rats; Rats, Wistar; Sildenafil Citrate; Sulfones; Uterus; Vasodilator Agents

2001
The role of L-arginine/nitric oxide pathway in the antinociceptive activity of pyridoxine in mouse.
    Arzneimittel-Forschung, 2001, Volume: 51, Issue:10

    Topics: Analgesics; Analgesics, Opioid; Animals; Arginine; Cyclic GMP; Dose-Response Relationship, Drug; Enzyme Inhibitors; Male; Methylene Blue; Mice; Morphine; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Pyridoxine; Vitamin B 6

2001
The effects of SIN-1 on contractility and cyclic GMP levels in the pregnant mouse uterus.
    Proceedings of the Western Pharmacology Society, 2001, Volume: 44

    Topics: Acetylcholine; Animals; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Guanylate Cyclase; In Vitro Techniques; Isometric Contraction; Methylene Blue; Mice; Molsidomine; Nitric Oxide Donors; Pregnancy; Uterine Contraction; Uterus

2001
Role of the preoptic carbon monoxide pathway in endotoxin fever in rats.
    Brain research, 2002, Feb-08, Volume: 927, Issue:1

    Topics: Animals; Carbon Monoxide; Cyclic GMP; Deuteroporphyrins; Endotoxemia; Enzyme Inhibitors; Fever; Heme; Heme Oxygenase (Decyclizing); Injections, Intraventricular; Lipopolysaccharides; Lysine; Male; Methylene Blue; Microinjections; Preoptic Area; Rats; Rats, Wistar; Vasodilator Agents

2002
Experimental evidence for a non-renin mediated pathway during TAME-esterase induced contractions in rat aorta in vitro.
    Indian journal of experimental biology, 2001, Volume: 39, Issue:9

    Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Aorta, Thoracic; Arginine; Captopril; Cyclic GMP; Dose-Response Relationship, Drug; Endothelium, Vascular; In Vitro Techniques; Male; Methylene Blue; Muscle Contraction; Muscle, Smooth, Vascular; Peptide Hydrolases; Rats; Rats, Sprague-Dawley; Renin; Signal Transduction; Tosylarginine Methyl Ester; Vasoconstriction

2001
Endothelium-dependent vasorelaxant and antiproliferative effects of apigenin.
    General pharmacology, 2000, Volume: 35, Issue:6

    Topics: Animals; Aorta, Thoracic; Apigenin; Cell Division; Cells, Cultured; Cyclic GMP; Endothelium, Vascular; Flavonoids; Isometric Contraction; Male; Methylene Blue; Muscle Relaxation; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Phorbol 12,13-Dibutyrate; Rats; Rats, Sprague-Dawley; Thymidine

2000
Cyclic AMP-mediated increase in L-type calcium current (ICa,L) by nitroglycerin in guinea-pig ventricular myocytes.
    Cellular and molecular biology (Noisy-le-Grand, France), 2002, Volume: 48, Issue:2

    Topics: 1-Methyl-3-isobutylxanthine; Animals; Calcium Signaling; Cells, Cultured; Cyclic AMP; Cyclic GMP; Dialysis; Guinea Pigs; Heart Ventricles; Isoproterenol; Methylene Blue; Nitroglycerin

2002
Catastrophic cardiovascular adverse reactions to protamine are nitric oxide/cyclic guanosine monophosphate dependent and endothelium mediated: should methylene blue be the treatment of choice?
    Chest, 2002, Volume: 122, Issue:3

    Topics: Anaphylaxis; Animals; Cyclic GMP; Endothelium, Vascular; Hemodynamics; Humans; Methylene Blue; Nitric Oxide; Protamines; Shock

2002
The kappa-opioid agonist (+/-)-bremazocine elicits peripheral antinociception by activation of the L-arginine/nitric oxide/cyclic GMP pathway.
    European journal of pharmacology, 2002, Nov-01, Volume: 454, Issue:1

    Topics: Analgesics; Animals; Arginine; Benzomorphans; Cyclic GMP; Guanylate Cyclase; Hyperalgesia; Male; Methylene Blue; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Pain; Phosphodiesterase Inhibitors; Purinones; Rats; Rats, Wistar; Receptors, Opioid, kappa

2002
Mechanisms underlying the hydrogen peroxide-induced, endothelium-independent relaxation of the norepinephrine-contraction in guinea-pig aorta.
    European journal of pharmacology, 2003, Jan-10, Volume: 459, Issue:1

    Topics: Animals; Aorta, Thoracic; Cyclic GMP; Dose-Response Relationship, Drug; Endothelium, Vascular; Guinea Pigs; Hydrogen Peroxide; In Vitro Techniques; Male; Methylene Blue; Myosin Light Chains; Nitroglycerin; Norepinephrine; Oxadiazoles; Phosphorylation; Purinones; Quinoxalines; Rats; Vasoconstriction; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents

2003
Effects of L-arginine and sodium nitroprusside on the spontaneous contractility of human non-pregnant uterus.
    Human reproduction (Oxford, England), 2003, Volume: 18, Issue:1

    Topics: Arginine; Cyclic GMP; Dose-Response Relationship, Drug; Drug Synergism; Female; Humans; In Vitro Techniques; Methylene Blue; Middle Aged; Nitric Oxide Donors; Nitroprusside; Osmolar Concentration; Uterine Contraction; Uterus

2003
A study on the mechanism by which sodium nitroprusside, a nitric oxide donor, applied to the anteroventral third ventricular region provokes facilitation of vasopressin secretion in conscious rats.
    Brain research, 2003, Apr-04, Volume: 968, Issue:1

    Topics: Analysis of Variance; Animals; Blood Pressure; Chlorides; Cyclic GMP; Dose-Response Relationship, Drug; Heart Rate; Hemoglobins; Male; Methylene Blue; Nitric Oxide Donors; Nitroprusside; Osmolar Concentration; Potassium; Rats; Rats, Wistar; Sodium; Third Ventricle; Time Factors; Vasopressins

2003
Preischemic infusion of alpha-human atrial natriuretic peptide elicits myoprotective effects against ischemia reperfusion in isolated rat hearts.
    Molecular and cellular biochemistry, 2003, Volume: 248, Issue:1-2

    Topics: Adenosine Triphosphate; Alkaloids; Animals; Atrial Natriuretic Factor; Benzophenanthridines; Cyclic GMP; Enzyme Inhibitors; Heart; Ischemia; Ischemic Preconditioning, Myocardial; Methylene Blue; Myocardial Ischemia; Myocardial Reperfusion; Myocardial Reperfusion Injury; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide; Phenanthridines; Potassium Channel Blockers; Potassium Channels; Protein Kinase C; Rats; Reperfusion; Time Factors; Tissue Distribution

2003
Burn-induced lung damage in rat is mediated by a nitric oxide/cGMP system.
    Shock (Augusta, Ga.), 2003, Volume: 20, Issue:4

    Topics: Animals; Base Sequence; Burns; Cyclic GMP; Enzyme Inhibitors; Female; Gene Expression; Guanylate Cyclase; Lung; Lung Injury; Male; Methylene Blue; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitroprusside; Oxadiazoles; Peroxidase; Quinoxalines; Rats; Rats, Sprague-Dawley; RNA, Messenger; Signal Transduction

2003
Methylene blue blocks cGMP production and disrupts directed migration of microglia to nerve lesions in the leech CNS.
    Journal of neurobiology, 2003, Volume: 57, Issue:2

    Topics: Animals; Axons; Cell Movement; Central Nervous System; Cyclic GMP; Enzyme Inhibitors; Leeches; Methylene Blue; Microglia; Nerve Crush; Neural Conduction; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III

2003
Methylene blue: an effective treatment for contrast medium-induced anaphylaxis.
    Medical science monitor : international medical journal of experimental and clinical research, 2003, Volume: 9, Issue:11

    Topics: Anaphylaxis; Contrast Media; Cyclic GMP; Enzyme Inhibitors; Humans; Methylene Blue; Nitric Oxide

2003
NO/cyclic GMP pathway mediates the relaxation of feline lower oesophageal sphincter.
    Autonomic & autacoid pharmacology, 2003, Volume: 23, Issue:3

    Topics: Aminoquinolines; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cats; Cyclic GMP; Dose-Response Relationship, Drug; Enzyme Inhibitors; Esophagogastric Junction; In Vitro Techniques; Indomethacin; Male; Methylene Blue; Molsidomine; Muscle Relaxation; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitroprusside; omega-N-Methylarginine; Oxadiazoles; Quinoxalines; Signal Transduction; Vasoactive Intestinal Peptide

2003
Reduction in [D-Ala2, NMePhe4, Gly-ol5]enkephalin-induced peripheral antinociception in diabetic rats: the role of the L-arginine/nitric oxide/cyclic guanosine monophosphate pathway.
    Anesthesia and analgesia, 2004, Volume: 98, Issue:1

    Topics: Analgesics, Opioid; Animals; Arginine; Blood Glucose; Cyclic GMP; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enzyme Inhibitors; Formaldehyde; Guanylate Cyclase; Male; Methylene Blue; Molsidomine; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Pain; Pain Measurement; Rats; Rats, Wistar

2004
Cholinergic-NO-cGMP mediation of sildenafil-induced antinociception.
    Indian journal of experimental biology, 2004, Volume: 42, Issue:4

    Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Acetic Acid; Acetylcholine; Animals; Carrageenan; Cholinergic Agents; Cholinesterase Inhibitors; Cyclic GMP; Cyclic Nucleotide Phosphodiesterases, Type 5; Dose-Response Relationship, Drug; Drug Combinations; Enzyme Inhibitors; Female; Guanylate Cyclase; Hyperalgesia; Male; Methylene Blue; Mice; Neostigmine; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Pain; Pain Measurement; Phosphodiesterase Inhibitors; Piperazines; Purines; Rats; Sildenafil Citrate; Sulfones

2004
Relaxant action of sildenafil citrate (Viagra) on human myometrium of pregnancy.
    American journal of obstetrics and gynecology, 2004, Volume: 191, Issue:1

    Topics: Cyclic GMP; Dose-Response Relationship, Drug; Female; Humans; Methylene Blue; Myometrium; Phosphodiesterase Inhibitors; Piperazines; Potassium Channels; Pregnancy; Purines; Sildenafil Citrate; Sulfones; Uterine Contraction

2004
Involvement of a nitric oxide-cyclic guanosine monophosphate pathway in control of fallopian tube contractility.
    Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology, 2004, Volume: 19, Issue:5

    Topics: Adult; Cyclic GMP; Enzyme Inhibitors; Fallopian Tubes; Female; Guanylate Cyclase; Humans; In Vitro Techniques; Methylene Blue; Muscle Contraction; Muscle, Smooth; Nitric Oxide; Nitric Oxide Donors; Nitrogen Oxides; Oxadiazoles; Quinoxalines; Spermine

2004
Comparative relaxant effects of YC-1 and DETA/NO on spontaneous contractions and the levels of cGMP of isolated pregnant rat myometrium.
    European journal of pharmacology, 2005, Jul-11, Volume: 517, Issue:3

    Topics: Animals; Cyclic GMP; Dose-Response Relationship, Drug; Female; In Vitro Techniques; Indazoles; Male; Methylene Blue; Muscle Relaxation; Myometrium; Nitric Oxide Donors; Pregnancy; Rats; Rats, Wistar; Time Factors; Triazenes; Uterine Contraction

2005
Nitric oxide-dependent reduction in soluble guanylate cyclase functionality accounts for early lipopolysaccharide-induced changes in vascular reactivity.
    Molecular pharmacology, 2006, Volume: 69, Issue:3

    Topics: Animals; Aorta; Blood Pressure; Cyclic GMP; Endotoxemia; Enzyme Inhibitors; Female; Guanylate Cyclase; Lipopolysaccharides; Lung; Methylene Blue; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitroprusside; Phenylephrine; Rats; Rats, Wistar; Vasoconstriction; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents

2006
Probable activation of the opioid receptor-nitric oxide-cyclic GMP-K+ channels pathway by codeine.
    Pharmacology, biochemistry, and behavior, 2005, Volume: 82, Issue:4

    Topics: 4-Aminopyridine; Analgesics, Opioid; Animals; Codeine; Cyclic GMP; Female; Glyburide; Methylene Blue; Naloxone; NG-Nitroarginine Methyl Ester; Nitric Oxide; Potassium Channels; Rats; Rats, Wistar; Receptors, Opioid; Tetraethylammonium; Tolbutamide

2005
Rewarding properties of sildenafil citrate in mice: role of the nitric oxide-cyclic GMP pathway.
    Psychopharmacology, 2006, Volume: 185, Issue:2

    Topics: Animals; Arginine; Conditioning, Psychological; Cyclic GMP; Dose-Response Relationship, Drug; Guanylate Cyclase; Male; Methylene Blue; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide; Phosphodiesterase Inhibitors; Piperazines; Purines; Reward; Sildenafil Citrate; Sulfones

2006
The proconvulsant effect of sildenafil in mice: role of nitric oxide-cGMP pathway.
    British journal of pharmacology, 2006, Volume: 147, Issue:8

    Topics: Animals; Arginine; Bicuculline; Cyclic GMP; Dose-Response Relationship, Drug; Male; Methylene Blue; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitroprusside; Pentylenetetrazole; Phosphodiesterase Inhibitors; Piperazines; Purines; Seizures; Signal Transduction; Sildenafil Citrate; Sulfones

2006
Sildenafil induces hyperalgesia via activation of the NO-cGMP pathway in the rat neuropathic pain model.
    Inflammopharmacology, 2006, Volume: 14, Issue:1-2

    Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Animals; Chronic Disease; Cyclic GMP; Cyclic Nucleotide Phosphodiesterases, Type 5; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Hyperalgesia; Injections, Spinal; Male; Methylene Blue; NG-Nitroarginine Methyl Ester; Nitric Oxide; Pain; Pain Threshold; Piperazines; Purines; Rats; Rats, Wistar; Sciatic Neuropathy; Signal Transduction; Sildenafil Citrate; Sulfones

2006
The antinociceptive activity of Muntingia calabura aqueous extract and the involvement of L-arginine/nitric oxide/cyclic guanosine monophosphate pathway in its observed activity in mice.
    Fundamental & clinical pharmacology, 2006, Volume: 20, Issue:4

    Topics: Acetic Acid; Analgesics; Animals; Arginine; Cyclic GMP; Dose-Response Relationship, Drug; Elaeocarpaceae; Enzyme Inhibitors; Guanylate Cyclase; Male; Methylene Blue; Mice; Mice, Inbred BALB C; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Pain; Pain Measurement; Plant Extracts; Plant Leaves; Signal Transduction

2006
Endothelium-dependent induction of vasorelaxation by the butanol extract of Phellinus igniarius in isolated rat aorta.
    The American journal of Chinese medicine, 2006, Volume: 34, Issue:4

    Topics: Animals; Aorta; Atropine; Butanols; Cyclic GMP; Diltiazem; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Inhibitors; Glyburide; In Vitro Techniques; Indomethacin; Male; Methylene Blue; NG-Nitroarginine Methyl Ester; Oxadiazoles; Polyporaceae; Propranolol; Quinoxalines; Rats; Rats, Sprague-Dawley; Tetraethylammonium; Vasodilation; Vasodilator Agents; Verapamil

2006
Pharmacological mechanisms involved in the vasodilator effects of extracts from Echinodorus grandiflorus.
    Journal of ethnopharmacology, 2007, Apr-20, Volume: 111, Issue:1

    Topics: Alismataceae; Animals; Aorta; Azepines; Brazil; Cyclic GMP; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Inhibitors; Guanylate Cyclase; In Vitro Techniques; Kidney; Methylene Blue; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Plant Extracts; Plant Leaves; Platelet Membrane Glycoproteins; Rabbits; Receptors, G-Protein-Coupled; Renal Circulation; Triazoles; Vasodilation; Vasodilator Agents

2007
Effect of manganese on luteinizing hormone-releasing hormone secretion in adult male rats.
    Toxicological sciences : an official journal of the Society of Toxicology, 2007, Volume: 97, Issue:1

    Topics: Age Factors; Animals; Carbazoles; Chlorides; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Female; Gonadotropin-Releasing Hormone; Guanylate Cyclase; Hemoglobins; Hypothalamus; In Vitro Techniques; Indoles; Male; Manganese Compounds; Methylene Blue; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Protein Kinase Inhibitors; Rats; Rats, Sprague-Dawley; Sex Factors; Signal Transduction

2007
Modulation of vascular reactivity in normal, hypertensive and diabetic rat aortae by a non-antioxidant flavonoid.
    Pharmacological research, 2007, Volume: 55, Issue:5

    Topics: Acetylcholine; Animals; Aorta, Thoracic; Cyclic GMP; Cyclooxygenase Inhibitors; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Drug Interactions; Endothelium, Vascular; Enzyme Inhibitors; Flavones; Flavonoids; Guanylate Cyclase; Hypertension; Indomethacin; Male; Methylene Blue; Muscle, Smooth, Vascular; NAD; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; Potassium Chloride; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Vasodilation; Vasodilator Agents

2007
Deleterious effect of nitric oxide inhibition in chronic hepatopulmonary syndrome.
    European journal of gastroenterology & hepatology, 2007, Volume: 19, Issue:4

    Topics: Antihypertensive Agents; Blood Pressure; Chronic Disease; Curcumin; Cyclic GMP; Echocardiography; Female; Hepatopulmonary Syndrome; Humans; Lypressin; Methylene Blue; Middle Aged; Nitric Oxide; Terlipressin; Treatment Failure; Vascular Resistance

2007
Is the cyclic GMP system underestimated by intensive care and emergency teams?
    Medical hypotheses, 2007, Volume: 69, Issue:3

    Topics: Animals; Blood Circulation; Blood Pressure; Catecholamines; Critical Care; Cyclic GMP; Emergency Medicine; Humans; Inflammation; Lactates; Methylene Blue; Models, Biological; Nitric Oxide; Norepinephrine; Shock

2007
Intracerebroventricular administration of nitric oxide-sensitive guanylyl cyclase inhibitors induces catalepsy in mice.
    Psychopharmacology, 2007, Volume: 194, Issue:2

    Topics: Animals; Arginine; Behavior, Animal; Catalepsy; Corpus Striatum; Cyclic GMP; Dose-Response Relationship, Drug; Enzyme Inhibitors; Guanylate Cyclase; Indazoles; Injections, Intraventricular; Male; Methylene Blue; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Oxadiazoles; Quinoxalines; Receptors, Cytoplasmic and Nuclear; Signal Transduction; Soluble Guanylyl Cyclase; Time Factors

2007
Nitroglycerin on contractile force in canine cardiac Purkinje fibers.
    Methods and findings in experimental and clinical pharmacology, 2007, Volume: 29, Issue:4

    Topics: Animals; Cardiotonic Agents; Cobalt; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Dogs; Dose-Response Relationship, Drug; Electric Stimulation; Enzyme Inhibitors; Guanylate Cyclase; In Vitro Techniques; Isoproterenol; Methylene Blue; Muscle Strength; Myocardial Contraction; Nitric Oxide Donors; Nitroglycerin; Nitroprusside; Potassium; Potassium Channel Blockers; Purkinje Fibers; Tetraethylammonium

2007
Twenty-four-hour variation of L-arginine/nitric oxide/cyclic guanosine monophosphate pathway demonstrated by the mouse visceral pain model.
    Chronobiology international, 2007, Volume: 24, Issue:3

    Topics: Abdominal Pain; Analgesics; Animals; Arginine; Benzoquinones; Circadian Rhythm; Cyclic GMP; Enzyme Inhibitors; Male; Methylene Blue; Mice; Mice, Inbred Strains; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitrites; Nitroprusside; Pain; Pain Measurement; Signal Transduction

2007
Role of the spinal cord heme oxygenase-carbon monoxide-cGMP pathway in the nociceptive response of rats.
    European journal of pharmacology, 2008, Feb-26, Volume: 581, Issue:1-2

    Topics: Animals; Carbon Monoxide; Cyclic GMP; Deuteroporphyrins; Heme; Heme Oxygenase (Decyclizing); Lysine; Male; Methylene Blue; Pain; Rats; Rats, Sprague-Dawley; Spinal Cord

2008
Lysozyme, a mediator of sepsis that produces vasodilation by hydrogen peroxide signaling in an arterial preparation.
    American journal of physiology. Heart and circulatory physiology, 2008, Volume: 294, Issue:4

    Topics: Aminoquinolines; Animals; Carotid Artery, Internal; Catalase; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Cyclooxygenase Inhibitors; Dogs; Dose-Response Relationship, Drug; Enzyme Inhibitors; Ethanol; Free Radical Scavengers; Guanylate Cyclase; Humans; Hydrogen Peroxide; Hydroquinones; In Vitro Techniques; Indomethacin; Mannitol; Mesenteric Artery, Superior; Methylene Blue; Muramidase; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Oxadiazoles; Phenylephrine; Prostaglandins; Protein Kinase Inhibitors; Quinoxalines; Receptors, Cytoplasmic and Nuclear; Sepsis; Signal Transduction; Soluble Guanylyl Cyclase; Thionucleotides; Time Factors; Vasoconstrictor Agents; Vasodilation

2008
The effect of guanylate cyclase inhibitors on non-adrenergic and non-cholinergic neurogenic relaxations of the South American opossum lower esophageal sphincter.
    Fundamental & clinical pharmacology, 2008, Volume: 22, Issue:3

    Topics: Aminoquinolines; Animals; Cyclic GMP; Cysteamine; Electric Stimulation; Esophageal Sphincter, Lower; Female; Guanylate Cyclase; Hydrazines; Hydroxylamine; In Vitro Techniques; Male; Methylene Blue; Muscle Relaxation; Nitric Oxide; Nitric Oxide Donors; Nitroprusside; Opossums; Oxadiazoles; Penicillamine; Receptors, Cytoplasmic and Nuclear; Soluble Guanylyl Cyclase

2008
Antidepressant-like effect of folic acid: Involvement of NMDA receptors and L-arginine-nitric oxide-cyclic guanosine monophosphate pathway.
    European journal of pharmacology, 2008, Nov-19, Volume: 598, Issue:1-3

    Topics: Animals; Antidepressive Agents; Arginine; Cyclic GMP; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Female; Folic Acid; Indazoles; Injections, Intraventricular; Male; Methylene Blue; Mice; N-Methylaspartate; Nitric Oxide; Nitric Oxide Donors; Receptors, N-Methyl-D-Aspartate; S-Nitroso-N-Acetylpenicillamine; Signal Transduction; Swimming; Vitamin B Complex

2008
Late, but not early, inhibition of soluble guanylate cyclase decreases mortality in a rat sepsis model.
    The Journal of pharmacology and experimental therapeutics, 2009, Volume: 328, Issue:3

    Topics: Animals; Aorta, Thoracic; Blood Pressure; Cecum; Cyclic GMP; Disease Models, Animal; Drug Administration Schedule; Enzyme Inhibitors; Female; Guanylate Cyclase; Methylene Blue; Mortality; Oxadiazoles; Quinoxalines; Rats; Rats, Wistar; RNA, Messenger; Sepsis; Vasoconstriction

2009
Role of ventral hippocampal nitric oxide/cGMP pathway in anxiety-related behaviors in rats submitted to the elevated T-maze.
    Behavioural brain research, 2010, Feb-11, Volume: 207, Issue:1

    Topics: Analysis of Variance; Animals; Anti-Anxiety Agents; Anxiety; Avoidance Learning; Behavior, Animal; Cyclic GMP; Dose-Response Relationship, Drug; Enzyme Inhibitors; Escape Reaction; Exploratory Behavior; Hippocampus; Indazoles; Male; Methylene Blue; Motor Activity; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitroprusside; Rats; Rats, Wistar; Staining and Labeling

2010
Involvement of nitric oxide-cGMP pathway in the anticonvulsant effects of lithium chloride on PTZ-induced seizure in mice.
    Epilepsy research, 2010, Volume: 89, Issue:2-3

    Topics: Animals; Anticonvulsants; Arginine; Convulsants; Cyclic GMP; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Indazoles; Injections, Intraperitoneal; Lithium Chloride; Male; Methylene Blue; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Pentylenetetrazole; Phosphodiesterase Inhibitors; Piperazines; Purines; Seizures; Sildenafil Citrate; Sulfones; Treatment Outcome

2010
(+/-)-Praeruptorin A enantiomers exert distinct relaxant effects on isolated rat aorta rings dependent on endothelium and nitric oxide synthesis.
    Chemico-biological interactions, 2010, Jul-30, Volume: 186, Issue:2

    Topics: Animals; Aorta, Thoracic; Calcium Signaling; Coumarins; Cyclic GMP; Drugs, Chinese Herbal; Endothelium, Vascular; In Vitro Techniques; Ligands; Male; Methylene Blue; NG-Nitroarginine Methyl Ester; Nitric Oxide; Phenylephrine; Potassium Chloride; Rats; Rats, Sprague-Dawley; Stereoisomerism; Structure-Activity Relationship; Vasodilation; Vasodilator Agents

2010
Lead-induced phytotoxicity mechanism involved in seed germination and seedling growth of wheat (Triticum aestivum L.).
    Ecotoxicology and environmental safety, 2010, Volume: 73, Issue:8

    Topics: Cyclic GMP; Dose-Response Relationship, Drug; Enzyme Inhibitors; Germination; Guanylate Cyclase; Hydrogen Peroxide; Lead; Lipid Peroxidation; Methylene Blue; Nitric Oxide; Seedlings; Signal Transduction; Soil Pollutants; Triticum

2010
Possible participation of nitric oxide/cyclic guanosine monophosphate/protein kinase C/ATP-sensitive K(+) channels pathway in the systemic antinociception of flavokawin B.
    Basic & clinical pharmacology & toxicology, 2011, Volume: 108, Issue:6

    Topics: Analgesics; Animals; Arginine; Cyclic GMP; Dose-Response Relationship, Drug; Enzyme Inhibitors; Flavonoids; Glyburide; Hypoglycemic Agents; Male; Methylene Blue; Mice; Mice, Inbred ICR; Nitric Oxide; Nitric Oxide Synthase; Pain; Potassium Channels; Protein Kinase C; Signal Transduction

2011
Methylene blue in the treatment of refractory shock from an amlodipine overdose.
    Annals of emergency medicine, 2011, Volume: 58, Issue:6

    Topics: Adult; Amlodipine; Cyclic GMP; Female; Humans; Methylene Blue; Shock; Vasodilator Agents

2011
Endothelial nitric oxide synthase is a key mediator of interleukin-2-induced hypotension and vascular leak syndrome.
    Journal of immunotherapy (Hagerstown, Md. : 1997), 2011, Volume: 34, Issue:5

    Topics: Animals; Blood Pressure; Capillary Leak Syndrome; Carcinoma, Renal Cell; Cyclic GMP; Enzyme Inhibitors; Guanylate Cyclase; Humans; Hypotension; Interleukin-2; Manganese; Melanoma; Methylene Blue; Mice; Mice, Inbred Strains; Mice, Knockout; Nitric Oxide; Nitric Oxide Synthase Type III; omega-N-Methylarginine; Organometallic Compounds; Receptors, Cytoplasmic and Nuclear; RNA, Messenger; Soluble Guanylyl Cyclase; Superoxides

2011
Thymoquinone produced antianxiety-like effects in mice through modulation of GABA and NO levels.
    Pharmacological reports : PR, 2011, Volume: 63, Issue:3

    Topics: Animals; Anti-Anxiety Agents; Anxiety; Behavior, Animal; Benzoquinones; Brain; Cyclic GMP; Diazepam; Disease Models, Animal; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Male; Methylene Blue; Mice; Nigella sativa; Nitric Oxide; Stress, Psychological

2011
Antidepressant-like effect of 1-(7-methoxy-2-methyl-1,2,3,4-tetrahydro-isoquinolin-4-YL)-cyclohexanol, a putative trace amine receptor ligand involves l-arginine-nitric oxide-cyclic guanosine monophosphate pathway.
    Neuroscience letters, 2011, Oct-03, Volume: 503, Issue:2

    Topics: Analysis of Variance; Animals; Antidepressive Agents; Arginine; Biogenic Amines; Brain Chemistry; Cyclic GMP; Cyclohexanols; Depression; Guanylate Cyclase; Indazoles; Isoquinolines; Male; Methylene Blue; Mice; Motor Activity; Neurotransmitter Agents; Nitric Oxide; Nitric Oxide Synthase; Phosphodiesterase Inhibitors; Piperazines; Purines; Signal Transduction; Sildenafil Citrate; Sulfones; Swimming

2011
Cinnamyl alcohol attenuates vasoconstriction by activation of K⁺ channels via NO-cGMP-protein kinase G pathway and inhibition of Rho-kinase.
    Experimental & molecular medicine, 2012, Dec-31, Volume: 44, Issue:12

    Topics: Animals; Aorta; Atrial Natriuretic Factor; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Dipeptides; Human Umbilical Vein Endothelial Cells; Humans; In Vitro Techniques; Male; Methylene Blue; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Oxadiazoles; Phenylephrine; Phosphorylation; Potassium Channel Blockers; Potassium Channels; Propanols; Quinoxalines; Rats; Rats, Sprague-Dawley; rho-Associated Kinases; Signal Transduction; Vasoconstriction; Vasodilation

2012
Vasorelaxant effect of Prunus yedoensis bark.
    BMC complementary and alternative medicine, 2013, Feb-14, Volume: 13

    Topics: Animals; Aorta; Arginine; Calcium; Calcium Channel Blockers; Calcium Channels; Cyclic GMP; Endothelium, Vascular; Methylene Blue; NG-Nitroarginine Methyl Ester; Nitric Oxide; Phenylephrine; Plant Bark; Plant Extracts; Prunus; Rats; Rats, Sprague-Dawley; Vasoconstriction; Vasodilator Agents

2013
Antinociceptive effect of ethanol extract of leaves of Lannea coromandelica.
    Journal of ethnopharmacology, 2014, May-28, Volume: 154, Issue:1

    Topics: Acetic Acid; Anacardiaceae; Analgesics; Animals; Cyclic GMP; Ethanol; Female; Formaldehyde; Glutamic Acid; Glyburide; Hot Temperature; KATP Channels; Male; Methylene Blue; Mice; Pain; Phytotherapy; Plant Extracts; Plant Leaves; Solvents; Toxicity Tests, Acute

2014
Involvement of L-arginine/NO/cGMP/K(ATP) channel pathway in the peripheral antinociceptive actions of ellagic acid in the rat formalin test.
    Pharmacology, biochemistry, and behavior, 2014, Volume: 126

    Topics: Analgesics; Animals; Arginine; Cyclic GMP; Dose-Response Relationship, Drug; Drug Interactions; Ellagic Acid; Glyburide; KATP Channels; Male; Methylene Blue; Morphine; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitroprusside; Pain Measurement; Rats; Signal Transduction

2014
Possible involvement of L-arginine-nitric oxide (NO)-cyclic guanosine monophosphate (cGMP) signaling pathway in the antidepressant-like effect of Wuling mycelia powder in rat.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2016, Volume: 78

    Topics: Animals; Antidepressive Agents; Arginine; Cyclic GMP; Disease Models, Animal; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Feeding Behavior; Food Preferences; Hippocampus; Indazoles; Male; Methylene Blue; Mycelium; Nitric Oxide; Powders; Rats, Sprague-Dawley; Signal Transduction; Sildenafil Citrate; Stress, Psychological; Sucrose

2016
Antidepressant effect of pramipexole in mice forced swimming test: A cross talk between dopamine receptor and NMDA/nitric oxide/cGMP pathway.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2016, Volume: 81

    Topics: Animals; Antidepressive Agents; Arginine; Benzothiazoles; Cyclic GMP; Dizocilpine Maleate; Haloperidol; Immobilization; Injections, Intraperitoneal; Male; Methylene Blue; Mice; Motor Activity; N-Methylaspartate; NG-Nitroarginine Methyl Ester; Nitric Oxide; Pramipexole; Receptors, Dopamine; Signal Transduction; Sildenafil Citrate; Swimming

2016
Blocking soluble guanylate cyclase could be the present and future of NO/cGMP inhibition for vasoplegia treatment.
    Critical care (London, England), 2018, 04-20, Volume: 22, Issue:1

    Topics: Cyclic GMP; Drug Discovery; Humans; Methylene Blue; Nitrous Oxide; Soluble Guanylyl Cyclase; Vasoplegia

2018
Methylene Blue Analogues with Marginal Monoamine Oxidase Inhibition Retain Antidepressant-like Activity.
    ACS chemical neuroscience, 2018, 12-19, Volume: 9, Issue:12

    Topics: Animals; Antidepressive Agents; Antidepressive Agents, Tricyclic; Behavior, Animal; Cyclic GMP; Imipramine; Locomotion; Methylene Blue; Mitochondria; Monoamine Oxidase Inhibitors; Nitric Oxide; Rats

2018
The role of nitric oxide-cGMP pathway in selegiline antidepressant-like effect in the mice forced swim test.
    Pharmacological reports : PR, 2018, Volume: 70, Issue:5

    Topics: Animals; Antidepressive Agents; Arginine; Cyclic GMP; Drug Synergism; Fluoxetine; Guanidines; Hippocampus; Immobility Response, Tonic; Indazoles; Male; Methylene Blue; Mice; Motor Activity; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitrites; Prefrontal Cortex; Selegiline; Signal Transduction; Sildenafil Citrate; Swimming

2018
Pharmacological evidence for the relationship between the NMDA receptor and nitric oxide pathway and the antidepressant-like effects of glucagon-like peptide-2 in the mouse forced-swim test.
    Behavioural brain research, 2019, 05-17, Volume: 364

    Topics: Animals; Antidepressive Agents; Arginine; Cyclic GMP; Depression; Dizocilpine Maleate; Glucagon-Like Peptide 2; Indazoles; Male; Methylene Blue; Mice; Motor Activity; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Phosphodiesterase 5 Inhibitors; Receptors, N-Methyl-D-Aspartate; Serine; Signal Transduction; Sildenafil Citrate; Swimming

2019
Sub-lethal antimicrobial photodynamic inactivation affects Pseudomonas aeruginosa PAO1 quorum sensing and cyclic di-GMP regulatory systems.
    Photodiagnosis and photodynamic therapy, 2019, Volume: 27

    Topics: Biofilms; Cyclic GMP; Gene Expression Regulation, Bacterial; Genes, Bacterial; Methylene Blue; Photochemotherapy; Photosensitizing Agents; Pseudomonas aeruginosa; Quorum Sensing; Real-Time Polymerase Chain Reaction; Virulence Factors

2019
Methylene blue and the NO/cGMP pathway in solid organs transplants.
    Minerva anestesiologica, 2020, Volume: 86, Issue:4

    Topics: Cyclic GMP; Hemodynamics; Humans; Hypotension; Liver; Lung; Methylene Blue; Nitric Oxide; Reperfusion; Reperfusion Injury; Signal Transduction; Transplants; Vascular Resistance

2020
Effects of NO/cGMP inhibitors in a rat model of anaphylactoid shock.
    Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 2020, Volume: 53, Issue:3

    Topics: Anaphylaxis; Animals; Cyclic GMP; Disease Models, Animal; Enzyme Inhibitors; Indigo Carmine; Male; Methylene Blue; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rats; Rats, Wistar

2020
Antispasmodic Effect of Asperidine B, a Pyrrolidine Derivative, through Inhibition of L-Type Ca
    Molecules (Basel, Switzerland), 2021, Sep-09, Volume: 26, Issue:18

    Topics: Acetylcholine; Animals; Calcium; Calcium Channel Blockers; Calcium Channels, L-Type; Cyclic GMP; Ileum; Male; Methylene Blue; Muscle Contraction; Muscle, Smooth; NG-Nitroarginine Methyl Ester; Parasympatholytics; Potassium Chloride; Pyrrolidines; Rats, Wistar; Tetraethylammonium

2021
Mechanistic pathways of fibromyalgia induced by intermittent cold stress in mice is sex-dependently.
    Brain research bulletin, 2022, Volume: 187

    Topics: Adenosine Triphosphatases; Animals; Arginine; Cold-Shock Response; Cyclic GMP; Dizocilpine Maleate; Female; Fibromyalgia; Male; Methylene Blue; Mice; N-Methylaspartate; Nitric Oxide; Quality of Life; Receptors, N-Methyl-D-Aspartate

2022
The role of l -arginine/NO/cGMP/K ATP channel pathway in the local antinociceptive effect of berberine in the rat formalin test.
    Behavioural pharmacology, 2023, 12-01, Volume: 34, Issue:8

    Topics: Adenosine Triphosphate; Analgesics; Animals; Arginine; Berberine; Cyclic GMP; Glyburide; KATP Channels; Methylene Blue; NG-Nitroarginine Methyl Ester; Nitric Oxide; Pain Measurement; Rats; Rats, Wistar

2023
The L-arginine-NO-cGMP pathway mediates the locomotor activity alterations during the expression of sensitization to mephedrone in mice.
    Clinical and experimental pharmacology & physiology, 2023, Volume: 50, Issue:8

    Topics: Animals; Arginine; Cyclic GMP; Locomotion; Male; Methylene Blue; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide

2023