Page last updated: 2024-08-23

methyldopa and yohimbine

methyldopa has been researched along with yohimbine in 25 studies

Research

Studies (25)

TimeframeStudies, this research(%)All Research%
pre-199017 (68.00)18.7374
1990's6 (24.00)18.2507
2000's0 (0.00)29.6817
2010's2 (8.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Andén, NE1
da Cunha, SP; Dias, CC; França, LC; Meirelles, RS; Yassin, A1
Bhandare, PN; D'Souza, RS; Rataboli, PV1
Christensen, HD; Koss, MC; Mutzig, M1
Adithan, C; Bapna, JS; Raveendran, R; Sivagnanam, G; Thakur, LC1
Heise, A; Kroneberg, G2
Fähse, C; Lietz, W; Matthies, H1
Dietmann, K1
Boissier, JR; Giudicelli, JF; Simon, P3
van Zwieten, PA1
Farsang, C; Kunos, G; Mucci, L; Ramirez-Gonzalez, MD1
Clineschmidt, BV; Faison, EP; Flataker, LM; Haubrich, DR1
Koss, MC1
Fersel, J; Melman, A; Weinstein, P1
Christensen, HD; Gherezghiher, T; Koss, MC1
Roszkowski, AP; Schuler, ME1
Castro, RM; Cunha, SP; França, LC; Nagata, NY1
Gantenberg, NS; Járai, Z; Kunos, G; Lazar-Wesley, E; Li, SJ; Scanlon, MN; Varga, K1
Bock, C; Niederhoffer, N; Szabo, B1
HUDOCK, JJ; KHENTIGAN, A; LAWRENCE, W; VANAMEE, P1

Reviews

1 review(s) available for methyldopa and yohimbine

ArticleYear
Pharmacology of centrally acting hypotensive drugs.
    British journal of clinical pharmacology, 1980, Volume: 10 Suppl 1

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Antihypertensive Agents; Blood Pressure; Brain; Clonidine; Guanfacine; Guanidines; Heart Rate; Humans; Imidazoles; Methyldopa; Phenylacetates; Prazosin; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Receptors, Cholinergic; Yohimbine

1980

Other Studies

24 other study(ies) available for methyldopa and yohimbine

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Selective stimulation of central alpha-autoreceptors following treatment with alpha-methyldopa and FLA 136.
    Naunyn-Schmiedeberg's archives of pharmacology, 1979, Volume: 306, Issue:3

    Topics: Adrenergic alpha-Agonists; Animals; Brain; Drug Interactions; Male; Methyldopa; Nialamide; Norepinephrine; Normetanephrine; Rats; Reflex; Triazoles; Yohimbine

1979
Action of alpha-methyldopa on human umbilical circulation in vitro.
    Gynecologic and obstetric investigation, 1992, Volume: 33, Issue:4

    Topics: Blood Circulation; Drug Evaluation, Preclinical; Drug Therapy, Combination; Hemodynamics; Humans; Infant, Newborn; Methyldopa; Umbilical Arteries; Yohimbine

1992
Dual action of clonidine on ethanol-induced gastric lesions: is the imidazoline-preferring receptor involved?
    European journal of pharmacology, 1991, Jun-25, Volume: 199, Issue:2

    Topics: Adrenergic alpha-Agonists; Animals; Clonidine; Dose-Response Relationship, Drug; Ethanol; Guanabenz; Imidazoline Receptors; Male; Methyldopa; Oxymetazoline; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Drug; Stomach; Yohimbine

1991
CNS alpha 2-adrenoceptor induced mydriasis in conscious rats.
    Journal of ocular pharmacology, 1990,Summer, Volume: 6, Issue:2

    Topics: Anesthesia; Animals; Bis(4-Methyl-1-Homopiperazinylthiocarbonyl)disulfide; Central Nervous System; Clonidine; Light; Male; Methyldopa; Premedication; Pupil; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Yohimbine

1990
Alphamethyldopa analgesia: its possible mechanism of action.
    Archives internationales de pharmacodynamie et de therapie, 1985, Volume: 277, Issue:1

    Topics: Analgesics; Animals; Male; Methyldopa; Mice; Naloxone; Pain; Physostigmine; Reaction Time; Time Factors; Yohimbine

1985
Central nervous alpha-adrenergic receptors and the mode of action of alpha-methyldopa.
    Naunyn-Schmiedeberg's archives of pharmacology, 1973, Volume: 279, Issue:3

    Topics: Adrenergic alpha-Antagonists; Angiotensin II; Animals; Aorta; Blood Pressure; Catecholamines; Cats; Cerebral Ventricles; Cocaine; Dopamine; Dose-Response Relationship, Drug; Drug Interactions; Hypotension; Isoproterenol; Methyldopa; Norepinephrine; Perfusion; Phentolamine; Propranolol; Rats; Receptors, Adrenergic; Reserpine; Tyramine; Yohimbine

1973
-Sympathetic receptor stimulation in the brain and hypotensive activity of -methyldopa.
    European journal of pharmacology, 1972, Volume: 17, Issue:2

    Topics: Adrenergic alpha-Antagonists; Animals; Antihypertensive Agents; Blood Pressure; Brain; Cats; Cerebral Ventricles; Depression, Chemical; Dopamine; Dopamine Antagonists; Female; Male; Methyldopa; Normetanephrine; Perfusion; Phentolamine; Receptors, Adrenergic; Receptors, Drug; Yohimbine

1972
[Methamphetamine stimulation in mice].
    Acta biologica et medica Germanica, 1971, Volume: 26, Issue:6

    Topics: Animals; Dihydroxyphenylalanine; Methamphetamine; Methyldopa; Mice; Mice, Inbred Strains; Motor Activity; Reserpine; Stimulation, Chemical; Tetrabenazine; Yohimbine

1971
[Promotion of organ circulation by raubasine].
    Arzneimittel-Forschung, 1967, Volume: 17, Issue:8

    Topics: Animals; Arteries; Blood Circulation; Blood Flow Velocity; Blood Pressure; Blood Volume; Cardiac Output; Coronary Vessels; Digoxin; Dogs; Guinea Pigs; Heart Rate; Methyldopa; Myocardium; Oxygen Consumption; Rats; Reserpine; Strophanthins; Vascular Resistance; Vasodilator Agents; Veins; Yohimbine

1967
[Central effects of some adreno- and-or sympatholytic substances. 3. Ptosis, catalepsy, antagonism with respect to apomorphine and amphetamine].
    Archives internationales de pharmacodynamie et de therapie, 1968, Volume: 171, Issue:1

    Topics: Animals; Apomorphine; Blepharoptosis; Bretylium Compounds; Catalepsy; Central Nervous System; Chlorpromazine; Dextroamphetamine; Dibenzylchlorethamine; Ergotamine; Eyelids; Guanethidine; Humans; Methyldopa; Mice; Phenoxybenzamine; Phentolamine; Propranolol; Rats; Tranquilizing Agents; Yohimbine

1968
[Central effects of some adrenal- and/or sympatholytic substances. I. Action on the rectal temperature].
    Archives internationales de pharmacodynamie et de therapie, 1967, Volume: 168, Issue:1

    Topics: Animals; Body Temperature; Bretylium Compounds; Chlorpromazine; Dibenzylchlorethamine; Ergotamine; Guanethidine; Male; Methyldopa; Mice; Phenoxybenzamine; Phentolamine; Propranolol; Rats; Sympatholytics; Temperature; Tranquilizing Agents; Yohimbine

1967
[Central effects of some adrenergic blocking and-or sympatholytic substances. II. Action on spontaneous motility and potentialization of pentobarbital].
    Archives internationales de pharmacodynamie et de therapie, 1967, Volume: 169, Issue:2

    Topics: Animals; Antihypertensive Agents; Bretylium Compounds; Dibenzylchlorethamine; Drug Synergism; Ergotamine; Guanethidine; Methyldopa; Mice; Motor Activity; Pentobarbital; Phenoxybenzamine; Phentolamine; Propranolol; Sympatholytics; Yohimbine

1967
Possible role of an endogenous opiate in the cardiovascular effects of central alpha adrenoceptor stimulation in spontaneously hypertensive rats.
    The Journal of pharmacology and experimental therapeutics, 1980, Volume: 214, Issue:1

    Topics: Anesthesia; Animals; Blood Pressure; Clonidine; Dose-Response Relationship, Drug; Drug Interactions; Endorphins; Heart Rate; Hypertension; Male; Methyldopa; Morphine; Naloxone; Naltrexone; Rats; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Receptors, Opioid; Time Factors; Yohimbine

1980
alpha-methyldopa reduces locomotor activity in rats via its metabolite, alpha-methylnorepinephrine, acting on alpha 2-adrenoceptors.
    Archives internationales de pharmacodynamie et de therapie, 1980, Volume: 244, Issue:2

    Topics: Animals; Clonidine; Depression, Chemical; Dose-Response Relationship, Drug; Drug Antagonism; Female; Methyldopa; Motor Activity; Nordefrin; Norepinephrine; Prazosin; Rats; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Yohimbine

1980
Methyldopa produces central inhibition of parasympathetic activity in the cat.
    Naunyn-Schmiedeberg's archives of pharmacology, 1980, Volume: 314, Issue:2

    Topics: Animals; Cats; Ciliary Body; Epinephrine; Female; Iris; Male; Methyldopa; Mydriatics; Parasympathetic Nervous System; Phenoxybenzamine; Pupil; Receptors, Adrenergic, alpha; Yohimbine

1980
Further studies on the effect of chronic alpha-methyldopa administration upon the central nervous system and sexual function in male rats.
    The Journal of urology, 1984, Volume: 132, Issue:4

    Topics: Animals; Carbidopa; Central Nervous System; Erectile Dysfunction; Humans; Libido; Male; Methyldopa; Norepinephrine; Penis; Rats; Reflex; Sexual Behavior, Animal; Substance Withdrawal Syndrome; Yohimbine

1984
Studies on the mechanism of methyl-dopa-induced mydriasis in the cat.
    Naunyn-Schmiedeberg's archives of pharmacology, 1982, Volume: 320, Issue:1

    Topics: Animals; Bis(4-Methyl-1-Homopiperazinylthiocarbonyl)disulfide; Cats; Female; Hydrazines; Injections, Intraventricular; Male; Methyldopa; Mydriatics; Prazosin; Pupil; Time Factors; Yohimbine

1982
Augmentation of chloral hydrate induced sleep by centrally acting antihypertensive agents.
    Proceedings of the Western Pharmacology Society, 1982, Volume: 25

    Topics: Animals; Antihypertensive Agents; Chloral Hydrate; Drug Synergism; Male; Methyldopa; Mice; Sleep; Yohimbine

1982
In vitro study of the effect of clonidine on human umbilical artery motility.
    Gynecologic and obstetric investigation, 1994, Volume: 38, Issue:1

    Topics: Clonidine; Humans; In Vitro Techniques; Infant, Newborn; Methyldopa; Umbilical Arteries; Vasoconstriction; Yohimbine

1994
alpha-2-Adrenergic activation of proopiomelanocortin-containing neurons in the arcuate nucleus causes opioid-mediated hypotension and bradycardia.
    Neuroendocrinology, 1996, Volume: 63, Issue:3

    Topics: Adrenergic alpha-Agonists; Animals; Arcuate Nucleus of Hypothalamus; beta-Endorphin; Bradycardia; Hypotension; In Situ Hybridization; Male; Methyldopa; Microinjections; Neurons; Nordefrin; Pro-Opiomelanocortin; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha; RNA, Messenger; Yohimbine

1996
Analysis of the receptor involved in the central hypotensive effect of rilmenidine and moxonidine.
    Naunyn-Schmiedeberg's archives of pharmacology, 1999, Volume: 359, Issue:4

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Antihypertensive Agents; Benzazepines; Benzofurans; Blood Pressure; Dose-Response Relationship, Drug; Drug Interactions; Female; Heart Rate; Imidazoles; Imidazoline Receptors; Male; Methyldopa; Norepinephrine; Oxazoles; Rabbits; Receptors, Adrenergic, alpha-2; Receptors, Drug; Rilmenidine; Sympathetic Nervous System; Yohimbine

1999
THE EFFECT OF SEROTONIN AND SEROTONIN ANTAGONISTS ON EXTERNAL PANCREATIC SECRETION IN DOGS.
    The Journal of surgical research, 1963, Volume: 3

    Topics: Antihypertensive Agents; Cyproheptadine; Diphenhydramine; Dogs; Ergot Alkaloids; Ergotamine; Indoles; Methyldopa; Methylergonovine; Oxytocics; Pancreatic Juice; Prochlorperazine; Pyrimidines; Research; Reserpine; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Antagonists; Yohimbine

1963