Page last updated: 2024-08-23

methyldopa and urea

methyldopa has been researched along with urea in 28 studies

Research

Studies (28)

Timeframe	Studies, this research(%)	All Research%
pre-1990	24 (85.71)	18.7374
1990's	1 (3.57)	18.2507
2000's	0 (0.00)	29.6817
2010's	2 (7.14)	24.3611
2020's	1 (3.57)	2.80

Authors

Authors	Studies
Ax, F; Bonham, NM; Hallberg, A; Karlén, A; Lennernäs, H; Winiwarter, S	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Avdeef, A; Tam, KY	1
Lubbe, WF	1
Eales, L; Jessop, S	1
Bellinghieri, G; Ceruso, D; Emanuele, M; Frisina, N; Nicita-Mauro, V; Petrelli, LD	1
Giezendanner, L; Solheim, SB; Sundsfjord, JA	1
Bulpitt, CJ	2
Clark, AD; Hawkins, DF; Sevitt, LH	1
Gottlieb, AJ; Wurzel, HA	1
Pohl, JE; Swales, JD; Thurston, H	1
Seedat, YK	1
Baglin, A; Merceron, R; Milliez, P; Safar, M; Sobel, A	1
Chase, TN; Colburn, RW; Kopin, IJ; Ng, LK	1
Naidoo, DN; Seedat, YK	1
Gifford, RW	1
Brodwall, EK; Hansen, T; Myhre, E; Stenbaek, O	1
Koe, BK; Weissman, A	1
Holler, HD; Steinorth, G	1
Ashcroft, R; Eccleston, DW; Elliott, RW; Kerr, DN; Rastogi, SP; Volans, G; Webster, D	1
Hope, JG; Provan, GC	1
Bolzano, K; Krempler, F; Sandhofer, F	1
BARBOUR, BH; CHESNE, RB; WEIL, MH	1
CHEMERDA, JM; JACOB, TA; VITALI, RA	1
CHAZAN, JA; KLAPPER, MS; RICHARD, L	1
HARRIS, JE	1
Anireddy, JS; Avula, VKR; Chamarthi, NR; Mallepogu, V; Pasupuleti, VR; Ponne, VC; Vadabingi, N; Vallela, S; Zyryanov, GV	1

Trials

6 trial(s) available for methyldopa and urea

Article	Year
Antihypertensive therapy with timolol and alpha-methyldopa. A double-blind trial in patients with moderately severe hypertension. South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1976, Feb-28, Volume: 50, Issue:9 Topics: Adrenergic beta-Antagonists; Adult; Clinical Trials as Topic; Creatinine; Drug Therapy, Combination; Female; Heart; Humans; Hypertension; Male; Methyldopa; Middle Aged; Placebos; Propanolamines; Thiadiazoles; Urea	1976
The effect of spironolactone (Aldactone) and methyldopa in low and normal renin hypertension. Acta medica Scandinavica, 1975, Volume: 197, Issue:6 Topics: Adult; Aged; Blood Pressure; Cholesterol; Clinical Trials as Topic; Depression, Chemical; Drug Therapy, Combination; Female; Humans; Hypertension; Male; Methyldopa; Middle Aged; Placebos; Potassium; Renin; Spironolactone; Time Factors; Urea; Uric Acid	1975
Methyldopa combined with prindolol in the treatment of severe hypertension. South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1974, Aug-10, Volume: 48, Issue:38 Topics: Blood Pressure; Clinical Trials as Topic; Drug Synergism; Drug Therapy, Combination; Female; Furosemide; Humans; Hypertension; Male; Methyldopa; Pindolol; Pulse; Urea	1974
Ethacrynic acid alone and in combination with methyldopa in the management of mild hypertension. A report of 23 patients. Internationale Zeitschrift fur klinische Pharmakologie, Therapie, und Toxikologie. International journal of clinical pharmacology, therapy, and toxicology, 1970, Volume: 3, Issue:3 Topics: Adult; Aged; Blood Pressure; Clinical Trials as Topic; Diarrhea; Drug Synergism; Ethacrynic Acid; Feeding and Eating Disorders; Female; Flatulence; Headache; Humans; Hypertension; Male; Methyldopa; Middle Aged; Nausea; Potassium; Taste; Urea; Uric Acid; Vomiting	1970
[Report on the clinical testing of the Sembrina--Saltucin. Drug combination for the treatment of hypertension]. Die Medizinische Welt, 1969, Oct-18, Volume: 42 Topics: Adult; Aged; Blood Glucose; Blood Pressure; Creatinine; Diuretics; Humans; Hypertension; Hypertension, Renal; Methyldopa; Middle Aged; Nitrogen; Potassium; Urea	1969
[A combination of methyldopa, hydrochlorothiazide and amiloride in the treatment of essential hypertension]. Acta medica Austriaca, 1984, Volume: 11, Issue:2 Topics: Adult; Aged; Amiloride; Blood Pressure; Clinical Trials as Topic; Creatinine; Drug Combinations; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Methyldopa; Middle Aged; Placebos; Posture; Pulse; Pyrazines; Urea; Uric Acid	1984

Other Studies

22 other study(ies) available for methyldopa and urea

Article	Year
Correlation of human jejunal permeability (in vivo) of drugs with experimentally and theoretically derived parameters. A multivariate data analysis approach. Journal of medicinal chemistry, 1998, Dec-03, Volume: 41, Issue:25 Topics: Humans; Intestinal Absorption; Jejunum; Models, Biological; Multivariate Analysis; Permeability; Pharmaceutical Preparations; Structure-Activity Relationship	1998
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
How well can the Caco-2/Madin-Darby canine kidney models predict effective human jejunal permeability? Journal of medicinal chemistry, 2010, May-13, Volume: 53, Issue:9 Topics: Animals; Disease Models, Animal; Dogs; Humans; Jejunal Diseases; Kidney Diseases; Models, Biological; Permeability; Porosity; Regression Analysis	2010
Erythrocyte electrolyte content and sodium efflux in chronic renal failure. Nephron, 1977, Volume: 18, Issue:2 Topics: Adolescent; Adult; Biological Transport; Blood Pressure; Electrolytes; Erythrocytes; Female; Furosemide; Humans; Kidney Failure, Chronic; Male; Methyldopa; Middle Aged; Potassium; Sodium; Urea	1977
[Effect of alphamethyldopa on kidney function and of plasma renin activity in arterial hypertensive syndromes]. Bollettino della Societa italiana di cardiologia, 1976, Volume: 21, Issue:5 Topics: Adult; Glomerular Filtration Rate; Humans; Hypertension; Metabolic Clearance Rate; Methyldopa; Middle Aged; Potassium; Renin; Sodium; Urea	1976
Serum uric acid in hypertensive patients. British heart journal, 1975, Volume: 37, Issue:12 Topics: Adult; Age Factors; Aged; Benzothiadiazines; Blood Pressure; Diuretics; Female; Humans; Hypertension; Male; Methyldopa; Middle Aged; Sex Factors; Sodium Chloride Symporter Inhibitors; Time Factors; Urea; Uric Acid	1975
Use of frusemide in severe toxaemia of pregnancy. Lancet (London, England), 1972, Jan-01, Volume: 1, Issue:7740 Topics: Adult; Antihypertensive Agents; Female; Furosemide; Humans; Hypertension; Methyldopa; Pre-Eclampsia; Pregnancy; Renal Dialysis; Urea	1972
Protein-quinone interaction: in vitro induction of indirect antiglobulin reactions with methyldopa. Blood, 1974, Volume: 43, Issue:1 Topics: Antibodies, Anti-Idiotypic; Binding Sites, Antibody; Buffers; Carbon Radioisotopes; Chemical Precipitation; Coombs Test; Dialysis; Erythrocytes; gamma-Globulins; Humans; Hydroquinones; Immunoglobulin Fragments; Immunoglobulin G; Latex; Methyldopa; Microspheres; Molecular Weight; Papain; Protein Binding; Serum Albumin; Temperature; Time Factors; Trichloroacetic Acid; Ultracentrifugation; Urea	1974
Hypertension with renal impairment: influence of intensive therapy. The Quarterly journal of medicine, 1974, Volume: 43, Issue:172 Topics: Adolescent; Adult; Chronic Disease; Creatinine; Diazoxide; Female; Glomerulonephritis; Humans; Hypertension; Ischemia; Kidney; Kidney Diseases; Kidney Function Tests; Male; Methyldopa; Middle Aged; Papilledema; Polycystic Kidney Diseases; Propranolol; Pyelonephritis; Urea	1974
[Treatment of arterial hypertension with new drugs. 1. Severe arterial hypertension]. Acquisitions medicales recentes, 1972 Topics: Antihypertensive Agents; Body Weight; Clonidine; Diuresis; Furosemide; Hemodynamics; Humans; Hypertension; Methyldopa; Sodium; Sodium Chloride; Spironolactone; Urea	1972
L-dopa in Parkinsonism. A possible mechanism of action. Neurology, 1972, Volume: 22, Issue:7 Topics: Amines; Animals; Basal Ganglia; Brain; Carbon Isotopes; Cerebral Cortex; Corpus Striatum; Dihydroxyphenylalanine; Dopamine; Frontal Lobe; Hydroxydopamines; Methyldopa; Norepinephrine; Parkinson Disease; Rats; Serotonin; Tritium; Tyrosine; Urea	1972
Evaluation of amiloride combined with hydrochlorothiazide (Moduretic) in the treatment of hypertension. South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1973, Jul-21, Volume: 47, Issue:28 Topics: Adult; Aged; Amiloride; Benzothiadiazines; Diuretics; Drug Combinations; Female; Guanethidine; Humans; Hydrochlorothiazide; Hypertension; Male; Methyldopa; Middle Aged; Potassium; Propranolol; Pyrazines; Urea; Uremia	1973
Blood urea changes in hypertensive patients according to therapy given, blood pressure control, and serum potassium levels. British heart journal, 1974, Volume: 36, Issue:4 Topics: Benzyl Compounds; Diuretics; Female; Glomerular Filtration Rate; Guanethidine; Guanidines; Humans; Hypertension; Male; Methyldopa; Potassium; Reserpine; Urea	1974
Hypotensive effect of methyldopa in renal failure associated with hypertension. Acta medica Scandinavica, 1972, Volume: 191, Issue:4 Topics: Administration, Oral; Adult; Creatinine; Female; Humans; Hypertension, Renal; Injections, Intravenous; Kidney Failure, Chronic; Male; Methyldopa; Middle Aged; Physical Exertion; Posture; Urea	1972
m-Fluorotyrosine convulsions and mortality: relationship to catecholamine and citrate metabolism. The Journal of pharmacology and experimental therapeutics, 1967, Volume: 155, Issue:1 Topics: 5-Hydroxytryptophan; Amphetamine; Animals; Anticonvulsants; Atropine; Azoles; Brain; Chlordiazepoxide; Chlorpromazine; Citrates; Dihydroxyphenylalanine; Disulfiram; Drug Antagonism; Drug Synergism; Kidney; Lysergic Acid Diethylamide; Male; Methyldopa; Mice; Morphine; Nialamide; Norepinephrine; Pargyline; Phenobarbital; Phenytoin; Reserpine; Seizures; Serotonin; Strychnine; Tetrabenazine; Trimethadione; Tyrosine; Urea	1967
High dose frusemide in the treatment of hypertension in chronic renal insufficiency and of terminal renal failure. Postgraduate medical journal, 1971, Volume: 47 Topics: Adolescent; Adult; Creatine; Creatinine; Diuresis; Female; Furosemide; Gout; Humans; Hypertension, Renal; Hypokalemia; Kidney Failure, Chronic; Male; Metabolic Clearance Rate; Methyldopa; Middle Aged; Potassium; Pyelonephritis; Sodium; Spironolactone; Urea; Uric Acid; Urine	1971
Hematological effects of alpha-methyldopa. Scottish medical journal, 1967, Volume: 12, Issue:6 Topics: Adult; Aged; Anemia, Hemolytic; Blood Group Antigens; Coombs Test; Erythrocyte Aging; Female; Hemoglobinometry; Humans; Hypertension; Male; Methyldopa; Middle Aged; Urea	1967
ALPHA-METHYL DOPA FOR THE TREATMENT OF HYPERTENSION: CLINICAL AND PHARMACODYNAMIC STUDIES. Circulation, 1963, Volume: 28 Topics: Alkaline Phosphatase; Antihypertensive Agents; Bilirubin; Blood Cell Count; Blood Glucose; Blood Pressure; Blood Pressure Determination; Creatine; Creatinine; Dye Dilution Technique; Electrocardiography; Geriatrics; Humans; Hypertension; Methyldopa; Nitrogen; Sulfobromophthalein; Toxicology; Urea	1963
ANALOGS OF METHYLDOPA AND DOPA. HYDANTOIC ACIDS AND HYDANTOINS. Journal of medicinal chemistry, 1964, Volume: 7 Topics: Antihypertensive Agents; Chemistry, Pharmaceutical; Dihydroxyphenylalanine; Hydantoins; Methyldopa; Organic Chemicals; Research; Urea	1964
THE USE OF METHYLDOPA IN HYPERTENSION. Southern medical journal, 1964, Volume: 57 Topics: Aspartate Aminotransferases; Biomedical Research; Blood; Blood Urea Nitrogen; Chlorothiazide; Drug Therapy; Hydrochlorothiazide; Hypertension; Methyldopa; Pharmacology; Placebos; Sex; Toxicology; Urea	1964
CARDIOVASCULAR RENAL AGENTS AS THEY IMPINGE ON OPHTHALMIC PRACTICE. Investigative ophthalmology, 1964, Volume: 3 Topics: Antihypertensive Agents; Benzothiadiazines; Bretylium Compounds; Carbonic Anhydrase Inhibitors; Cardiovascular Agents; Diuretics; Drug Therapy; Glycerol; Guanethidine; Hexamethonium Compounds; Hydralazine; Mannitol; Mecamylamine; Methyldopa; Mineralocorticoid Receptor Antagonists; Ophthalmology; Organomercury Compounds; Pargyline; Pentolinium Tartrate; Renal Agents; Reserpine; Tetraethylammonium Compounds; Toxicology; Urea; Veratrum; Veratrum Alkaloids	1964
Multiple molecular targets mediated antioxidant activity, molecular docking, ADMET, QSAR and bioactivity studies of halo substituted urea derivatives of α-Methyl-l-DOPA. Bioorganic chemistry, 2020, Volume: 97 Topics: Animals; Antioxidants; Caco-2 Cells; Dogs; Humans; Madin Darby Canine Kidney Cells; Methyldopa; Molecular Docking Simulation; Quantitative Structure-Activity Relationship; Urea	2020