Page last updated: 2024-08-23

methyldopa and tyrosine

methyldopa has been researched along with tyrosine in 79 studies

Research

Studies (79)

TimeframeStudies, this research(%)All Research%
pre-199074 (93.67)18.7374
1990's1 (1.27)18.2507
2000's3 (3.80)29.6817
2010's1 (1.27)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cha, SH; Chairoungdua, A; Endou, H; Kanai, Y; Kim, DK; Matsuo, H1
Bellman, K; Knegtel, RM; Settimo, L1
Chase, GJ; Lorenzo, AV; Uretsky, NJ1
Clay, KL; Murphy, RC1
Chiflikian, MD; Esaian, NA; Manukhin, BN1
Nikolić, JV; Stepanović, SR; Varagić, VM1
Maître, L; Waldmeier, PC1
Atkins, FL; Beaven, MA; Keiser, HR1
Benoiton, NL; D'lorio, A; Sharma, S; Tong, JH1
Cotzias, GC; Gellene, R; Papavasiliou, PS1
Constantinidis, J1
Modigh, K1
Kopin, IJ; Sedvall, GC; Weise, VK1
Boyd, AE; Feldman, JM; Lebovitz, HE1
Mennear, JH; Rudzik, AD2
Stock, K; Westermann, E2
Norberg, KA1
Zenker, N1
Marxer, A; Schier, O1
Andén, NE; Butcher, SG; Engel, J1
Rubenson, A1
Karobath, M1
Axelrod, J; Weinshilboum, R1
Colombo, JP; Küffer, H; Peheim, E; Richterich, R1
Kledzik, GS; Meites, J1
Johnson, DG; Kopin, IJ; Thoa, NB1
Buse, MG; Rossini, AA1
Presthus, J1
Andén, NE; Engel, J1
Chase, TN; Colburn, RW; Kopin, IJ; Ng, LK1
Atkinson, M; Hartley, D; Lunts, LH; Ritchie, AC1
Crespin, SR; Jarett, L; Smith, RM1
Uretsky, NJ1
Laverty, R; Taylor, KM1
Ruthven, CR; Sandler, M1
Koe, BK; Weissman, A2
De Ropp, RS; Furst, A1
Kawabata, K1
Borud, O; Gjessing, LR; Nishimura, T1
Muscholl, E1
Goldberg, ME; Salama, AI1
Vanderkamp, H1
Dominic, JA; Moore, KE1
Mishima, Y; Tanay, A1
Chan, WC; Johnson, GE1
Degroot, LJ; Jaksina, S1
Jaques, R1
Hakanson, R1
Sachs, C1
Maître, L1
Holtmeier, HJ; Marongiu, F; von Klein-Wisenberg, A1
Ashcroft, GW; Berger, RJ; Eccleston, D; Evans, JI; Oswald, I; Thacore, VR1
Haefely, W; Hürlimann, A; Thoenen, H1
Burcin, A; Porter, CC; Totaro, JA; Wynosky, ER1
Kobayashi, I; Shichijo, K; Yamlada, T1
Bhargava, KP; Gupta, ML1
Arimura, A; Müller, EE; Sawano, S; Schally, AV1
Fernstrom, JD1
Gerhart, F; Hornsperger, JM; Jung, MJ; Wagner, J1
Iwao, J; Kato, E; Kawashima, Y; Matsumoto, J; Oya, M1
Boulton, AA; Juorio, AV1
Deleu, D; Ebinger, G; Michotte, Y; Sarre, S; Van Belle, K1
CONNAMACHER, RH; HESS, SM; OZAKI, M; UDENFRIEND, S1
CHAVEZ, B; MORAN, JF; SOURKES, TL1
KIMURA, S; MIKUNI, M; TAKESHIMA, M1
CONTRERAS, E; CROXATTO, R; HUIDOBRO, F1
BURKARD, WP; GEY, KF; PLETSCHER, A1
HORWITZ, D; SJOERDSMA, A1
JACOBY, GA; LADU, BN1
CAHEN, RL1
CARDOT, J1
ANDEN, NE1
MORAN, JF; SOURKES, TL1
CHO, MH; DOBKIN, AB; LEE, PK1
d'Ischia, M; Manini, P; Napolitano, A1
Borst, C; Holzgrabe, U1

Reviews

6 review(s) available for methyldopa and tyrosine

ArticleYear
Antihypertensive agents 1962-1968.
    Progress in drug research. Fortschritte der Arzneimittelforschung. Progres des recherches pharmaceutiques, 1969, Volume: 13

    Topics: Adrenergic beta-Antagonists; Animals; Antihypertensive Agents; Aromatic Amino Acid Decarboxylase Inhibitors; Blood Pressure; Butyrophenones; Catecholamines; Diazoxide; Guanidines; Heterocyclic Compounds; Humans; Hydrolases; Imidazoles; Indoles; Methyldopa; Monoamine Oxidase Inhibitors; Peptides; Piperazines; Propranolol; Prostaglandins; Pyrimidines; Quinazolines; Quinolines; Transferases; Triazines; Tyrosine

1969
Catecholamines.
    The New England journal of medicine, 1972, Aug-03, Volume: 287, Issue:5

    Topics: Adrenal Medulla; Affective Symptoms; Animals; Brain; Catechol O-Methyltransferase; Catecholamines; Dihydroxyphenylalanine; Dopamine beta-Hydroxylase; Humans; Hypertension; Methyldopa; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Nerve Endings; Neurons; Parkinson Disease; Receptors, Drug; Sympathetic Nervous System; Sympathomimetics; Synaptic Transmission; Tyrosine; Tyrosine 3-Monooxygenase

1972
[Other trials with drug therapy in parkinsonism].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1973, Oct-10, Volume: 93, Issue:28

    Topics: 5-Hydroxytryptophan; Amitriptyline; Animals; Dihydroxyphenylalanine; Disulfiram; Drug Evaluation; Drug Therapy, Combination; Humans; Imipramine; Methyldopa; Monoamine Oxidase Inhibitors; Parkinson Disease; Picolinic Acids; Rats; Serine; Time Factors; Tryptophan; Tyrosine

1973
The biosynthesis and metabolism of the catecholamines.
    Progress in medicinal chemistry, 1969, Volume: 6

    Topics: Alcohol Oxidoreductases; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Catecholamines; Dopa Decarboxylase; Dopamine; Epinephrine; Humans; Methyldopa; Methyltyrosines; Mixed Function Oxygenases; Monoamine Oxidase; Norepinephrine; Phenethylamines; Phenylalanine; Radioisotopes; Schizophrenia; Transferases; Tyrosine; Vanilmandelic Acid

1969
Autonomic nervous system: newer mechanisms of adrenergic blockade.
    Annual review of pharmacology, 1966, Volume: 6

    Topics: Methyldopa; Sympatholytics; Tyrosine

1966
Role of precursor availability in control of monoamine biosynthesis in brain.
    Physiological reviews, 1983, Volume: 63, Issue:2

    Topics: Animals; Appetite; Blood Pressure; Brain; Brain Chemistry; Catecholamines; Diabetes Mellitus; Diet; Growth Hormone; Humans; Liver Cirrhosis; Methyldopa; Pain; Phenylketonurias; Protein Binding; Rats; Serotonin; Serum Albumin; Tryptophan; Tryptophan Hydroxylase; Tyrosine; Tyrosine 3-Monooxygenase

1983

Trials

1 trial(s) available for methyldopa and tyrosine

ArticleYear
Modification of Parkinsonism--chronic treatment with L-dopa.
    The New England journal of medicine, 1969, Feb-13, Volume: 280, Issue:7

    Topics: Adult; Aged; Agranulocytosis; Aromatic Amino Acid Decarboxylase Inhibitors; Blood Urea Nitrogen; Blood-Brain Barrier; Chronic Disease; Dihydroxyphenylalanine; Dopamine; Feeding and Eating Disorders; Female; Humans; Huntington Disease; Male; Manganese; Mental Processes; Methyldopa; Middle Aged; Movement Disorders; Nausea; Neurologic Manifestations; Parkinson Disease; Phenylacetates; Placebos; Thyroid Function Tests; Tyrosine; Vomiting

1969

Other Studies

72 other study(ies) available for methyldopa and tyrosine

ArticleYear
Expression cloning of a Na+-independent aromatic amino acid transporter with structural similarity to H+/monocarboxylate transporters.
    The Journal of biological chemistry, 2001, May-18, Volume: 276, Issue:20

    Topics: Amino Acid Sequence; Amino Acid Transport Systems; Amino Acid Transport Systems, Neutral; Animals; Anion Transport Proteins; Bacterial Proteins; Carrier Proteins; Cloning, Molecular; Escherichia coli Proteins; Female; Intestine, Small; Kinetics; Levodopa; Mice; Molecular Sequence Data; Oocytes; Phenylalanine; Rats; Recombinant Proteins; Sequence Alignment; Sequence Homology, Amino Acid; Substrate Specificity; Tryptophan; Tyrosine; Xenopus laevis

2001
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
    Pharmaceutical research, 2014, Volume: 31, Issue:4

    Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation

2014
Effect of alpha-methyldopa on dopamine synthesis and release in rat striatum in vitro.
    The Journal of pharmacology and experimental therapeutics, 1975, Volume: 193, Issue:1

    Topics: Animals; Body Water; Brocresine; Corpus Striatum; Deoxyepinephrine; Dopamine; In Vitro Techniques; Male; Methyldopa; Rats; Tritium; Tyrosine; Tyrosine 3-Monooxygenase

1975
New procedure for isolation of amino acids based on selective hydrolysis of trimethylsilyl derivatives.
    Journal of chromatography, 1979, Dec-01, Volume: 164, Issue:4

    Topics: Amino Acids; Gas Chromatography-Mass Spectrometry; Humans; Levodopa; Methyldopa; Trimethylsilyl Compounds; Tyrosine

1979
[Effect of GABA on the synthesis, uptake and release of noradrenaline-H3 from brain slices].
    Fiziologicheskii zhurnal SSSR imeni I. M. Sechenova, 1978, Volume: 64, Issue:8

    Topics: Animals; Brain; Dopamine; Electric Stimulation; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Methyldopa; Norepinephrine; Rats; Tyrosine

1978
Effect of alpha-methyldopa and alpha-methyl-m-tyrosine on the amount of noradrenaline in the heart and brain of irradiated rats.
    Strahlentherapie, 1977, Volume: 153, Issue:6

    Topics: Animals; Brain; Heart; Male; Methyldopa; Myocardium; Norepinephrine; Radiation Injuries, Experimental; Rats; Tyrosine; X-Rays

1977
Comparison of short and long-lasting effects of pargyline on cerebral dopamine metabolism.
    Naunyn-Schmiedeberg's archives of pharmacology, 1976, Volume: 294, Issue:2

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain; Cisterna Magna; Corpus Striatum; Dopamine; Female; Homovanillic Acid; Injections; Injections, Intravenous; Levodopa; Methyldopa; Monoamine Oxidase; Pargyline; Rats; Time Factors; Tyrosine

1976
Dopa decarboxylase in medullary carcinoma of the thyroid.
    The New England journal of medicine, 1973, Sep-13, Volume: 289, Issue:11

    Topics: Adrenal Gland Neoplasms; Amine Oxidase (Copper-Containing); Aromatic Amino Acid Decarboxylase Inhibitors; Carbidopa; Carcinoma; Cresols; Dihydroxyphenylalanine; Dopa Decarboxylase; Histamine; Histidine; Humans; Hydrazines; Hydroxylamines; Methyldopa; Methylhistidines; Norepinephrine; Pheochromocytoma; Serotonin; Thyroid Gland; Thyroid Neoplasms; Tryptophan; Tyrosine; Tyrosine 3-Monooxygenase

1973
A new biosynthetic pathway to catecholamines via m-tyrosine.
    Advances in neurology, 1974, Volume: 5

    Topics: Adrenal Glands; Animals; Benzyl Compounds; Brain; Carbon Radioisotopes; Catalysis; Catecholamines; Dihydroxyphenylalanine; Hydroxylation; In Vitro Techniques; Iron; Liver; Methyldopa; Methyltyrosines; Mice; Monoiodotyrosine; NADP; Phenylalanine; Phenylalanine Hydroxylase; Phosphates; Pterins; Rats; Structure-Activity Relationship; Tyrosine

1974
[Monoamines and choreic syndromes].
    Revue neurologique, 1972, Volume: 127, Issue:1

    Topics: Amines; Butyrophenones; Chorea; Diazepam; Dihydroxyphenylalanine; Dopamine; Ganglia; Globus Pallidus; Homovanillic Acid; Humans; Huntington Disease; Mental Disorders; Methyldopa; Methyltyrosines; Models, Neurological; Movement Disorders; Phenothiazines; Physostigmine; Reserpine; Thalamus; Tranquilizing Agents; Tyrosine

1972
Functional aspects of 5-hydroxytryptamine turnover in the central nervous system.
    Acta physiologica Scandinavica. Supplementum, 1974, Volume: 403

    Topics: 5-Hydroxytryptophan; Acetamides; Animals; Antidepressive Agents; Brain; Catecholamines; Depression, Chemical; Dihydroxyphenylalanine; Fenclonine; Humans; Hydrazines; Imipramine; Male; Methyldopa; Motor Activity; Nialamide; Receptors, Drug; Reserpine; Serotonin; Stimulation, Chemical; Stress, Psychological; Tryptophan; Tyrosine

1974
Effect of false transmitters on norepinephrine synthesis.
    The Journal of pharmacology and experimental therapeutics, 1969, Volume: 170, Issue:2

    Topics: Animals; Carbon Isotopes; Chlorisondamine; Dihydroxyphenylalanine; Dopamine; Heart; In Vitro Techniques; Metaraminol; Methyldopa; Mixed Function Oxygenases; Myocardium; Norepinephrine; Octopamine; Pempidine; Rats; Synaptic Transmission; Time Factors; Tritium; Tyrosine

1969
Structural determinants of catecholamine action on in vitro insulin release.
    The Journal of pharmacology and experimental therapeutics, 1971, Volume: 176, Issue:3

    Topics: Animals; Butyrates; Catecholamines; Cricetinae; Cyclic AMP; Dihydroxyphenylalanine; Dopamine; Epinephrine; Glucose; In Vitro Techniques; Insulin; Insulin Secretion; Isoproterenol; Methyldopa; Norepinephrine; Pancreas; Phenethylamines; Phentolamine; Phenylacetates; Phenylalanine; Phenylephrine; Structure-Activity Relationship; Tyramine; Tyrosine

1971
Antagonism of analgesics by amine-depleting agents.
    The Journal of pharmacy and pharmacology, 1965, Volume: 17, Issue:5

    Topics: Animals; Aspirin; Biological Assay; Catecholamines; Methyldopa; Mice; Morphine; Reserpine; Tyrosine

1965
Effect of alpha-methyldopa and alpha-methyl-m-tyrosine on the mobilization of free fatty acids.
    Experientia, 1964, Sep-15, Volume: 20, Issue:9

    Topics: Adipose Tissue; Animals; Catecholamines; Enzymes; Fatty Acids; Glycerides; In Vitro Techniques; Metaraminol; Methyldopa; Methyltyrosines; Norepinephrine; Rats; Reserpine; Triglycerides; Tyramine; Tyrosine

1964
[On the significance of the noradrenaline content of fatty tissue for the mobilization of unesterified fatty acids].
    Naunyn-Schmiedebergs Archiv fur experimentelle Pathologie und Pharmakologie, 1965, Sep-27, Volume: 251, Issue:5

    Topics: Adipose Tissue; Adrenal Medulla; Animals; Cocaine; Cold Temperature; Enzymes; Epididymis; Epinephrine; Fatty Acids; In Vitro Techniques; Lipids; Male; Metaraminol; Methyldopa; Methyltyrosines; Nialamide; Norepinephrine; Normetanephrine; Octopamine; Pargyline; Rats; Reserpine; Transaminases; Tyramine; Tyrosine; Tyrosine Transaminase

1965
Drug-induced changes in monoamine levels in the sympathetic adrenergic ganglion cells and terminals. A histochemical study.
    Acta physiologica Scandinavica, 1965, Volume: 65, Issue:3

    Topics: 5-Hydroxytryptophan; Animals; Catecholamines; Dihydroxyphenylalanine; Dopamine; Ephedrine; Ganglia, Autonomic; Hydrazines; Methyldopa; Microscopy, Fluorescence; Nerve Endings; Neurochemistry; Nialamide; Pargyline; Rats; Reserpine; Tranylcypromine; Tyrosine

1965
The interaction of pyridoxal phosphate with tyrosine analogs.
    Journal of medicinal chemistry, 1966, Volume: 9, Issue:6

    Topics: Animals; Dihydroxyphenylalanine; Dopamine; Enzymes; Epinephrine; In Vitro Techniques; Liver; Male; Methyldopa; Methyltyrosines; Normetanephrine; Octopamine; Phenylalanine; Pyridoxal Phosphate; Rats; Transaminases; Tyramine; Tyrosine; Tyrosine Transaminase; Ultraviolet Rays

1966
Central dopamine and noradrenaline receptor activity of the amines formed from m-tyrosine, alpha-methyl-m-tyrosine and alpha-methyldopa.
    The Journal of pharmacy and pharmacology, 1970, Volume: 22, Issue:7

    Topics: Animals; Behavior, Animal; Brain; Dopamine; Male; Methyldopa; Methyltyrosines; Motor Activity; Norepinephrine; Rats; Receptors, Drug; Spinal Cord; Tyramine; Tyrosine

1970
Further studies on the mechanism of the central hypotensive effect of L-dopa, DL-m-tyrosine and L-alpha-methyldopa.
    The Journal of pharmacy and pharmacology, 1971, Volume: 23, Issue:3

    Topics: Animals; Arteries; Blood Pressure; Brain; Brain Chemistry; Depression, Chemical; Dihydroxyphenylalanine; Dopamine; Male; Methyldopa; Norepinephrine; Propionates; Rats; Tyrosine

1971
Catecholamines and the hydroxylation of tyrosine in synaptosomes isolated from rat brain.
    Proceedings of the National Academy of Sciences of the United States of America, 1971, Volume: 68, Issue:10

    Topics: Animals; Autoradiography; Brain; Catecholamines; Chromatography, Ion Exchange; Dihydroxyphenylalanine; Dopamine; Male; Methyldopa; Methyltyrosines; Mixed Function Oxygenases; Monoiodotyrosine; Norepinephrine; Normetanephrine; Octopamine; Phenethylamines; Rats; Serotonin; Synaptic Vesicles; Time Factors; Tritium; Tyramine; Tyrosine; Tyrosine 3-Monooxygenase

1971
[The determination of bilirubin as azobilirubin in plasma and serum with the Greiner electronic selective analyzer GSA II (author's transl)].
    Zeitschrift fur klinische Chemie und klinische Biochemie, 1974, Volume: 12, Issue:6

    Topics: Ascorbic Acid; Azo Compounds; Bilirubin; Chemistry, Clinical; Diazonium Compounds; Epinephrine; Hemoglobins; Hemolysis; Histidine; Humans; Hyperlipidemias; Levodopa; Methyldopa; Norepinephrine; Rifampin; Spectrophotometry, Ultraviolet; Statistics as Topic; Tyrosine

1974
Reinitiation of estrous cycles in light-induced constant estrous female rats by drugs.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1974, Volume: 146, Issue:4

    Topics: Amphetamine; Amphetamines; Animals; Autonomic Agents; Brain; Catecholamines; Dihydroxyphenylalanine; Estrus; Female; Iproniazid; Light; Luteinizing Hormone; Methyldopa; Ovulation; Periodicity; Pregnancy; Rats; Reserpine; Serotonin; Tyrosine

1974
Inhibition of norepinephrine biosynthesis by -methyl amino acids in the guinea-pig vas deferens.
    The Journal of pharmacology and experimental therapeutics, 1972, Volume: 180, Issue:1

    Topics: Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Carbon Isotopes; Dihydroxyphenylalanine; Dopamine; Guinea Pigs; Hypogastric Plexus; In Vitro Techniques; Male; Methylamines; Methyldopa; Methyltyrosines; Norepinephrine; Octopamine; Tritium; Tyramine; Tyrosine; Vas Deferens

1972
The effect of L-dopa on insulin release by isolated pancreatic islets of the rat.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 1973, Volume: 5, Issue:1

    Topics: Animals; Dihydroxyphenylalanine; Drug Synergism; Insulin; Insulin Secretion; Islets of Langerhans; Male; Methyldopa; Organ Culture Techniques; Radioimmunoassay; Rats; Species Specificity; Structure-Activity Relationship; Tyrosine

1973
Effect of L-DOPA and analogues on central dopamine and noradrenaline mechanisms.
    Advances in neurology, 1974, Volume: 5

    Topics: 5-Hydroxytryptophan; Acetamides; Animals; Apomorphine; Brain Chemistry; Clonidine; Corpus Striatum; Dopamine; Hydrazines; Levodopa; Methyldopa; Methyltyrosines; Movement; Nialamide; Norepinephrine; Octopamine; Rats; Receptors, Drug; Reflex; Reserpine; Spinal Cord; Stimulation, Chemical; Tyramine; Tyrosine

1974
L-dopa in Parkinsonism. A possible mechanism of action.
    Neurology, 1972, Volume: 22, Issue:7

    Topics: Amines; Animals; Basal Ganglia; Brain; Carbon Isotopes; Cerebral Cortex; Corpus Striatum; Dihydroxyphenylalanine; Dopamine; Frontal Lobe; Hydroxydopamines; Methyldopa; Norepinephrine; Parkinson Disease; Rats; Serotonin; Tritium; Tyrosine; Urea

1972
Saligenin analogs of l-DOPA and dl-alpha-methyl-DOPA.
    Journal of medicinal chemistry, 1974, Volume: 17, Issue:2

    Topics: Animals; Antiparkinson Agents; Blood Pressure; Desoxycorticosterone; Dihydroxyphenylalanine; Dopa Decarboxylase; Guinea Pigs; Haloperidol; Kidney; Methanol; Methyldopa; Methyltyrosines; Mice; Myocardium; Norepinephrine; Rats; Tyrosine

1974
Epinephrine binding to rat adipocytes and their subcellular fractions.
    Endocrinology, 1974, Volume: 94, Issue:3

    Topics: Adipose Tissue; Animals; Binding Sites; Cell Membrane; Dihydroxyphenylalanine; Epinephrine; Isoproterenol; Liver; Methyldopa; Microsomes; Mitochondria; Mitochondria, Liver; Phentolamine; Propranolol; Rats; Tritium; Tyrosine

1974
Effect of alpha-methyldopa on the metabolism of dopamine in the striatum of the rat.
    The Journal of pharmacology and experimental therapeutics, 1974, Volume: 189, Issue:2

    Topics: Animals; Brain Chemistry; Chromatography, Ion Exchange; Corpus Striatum; Dopamine; Homovanillic Acid; Hydroxydopamines; Male; Methyldopa; Monoamine Oxidase; Pargyline; Phenylacetates; Rats; Time Factors; Tritium; Tyrosine

1974
The fluorometric assay of catecholamines and related compounds: improvements and extensions to the hydroxyindole technique.
    Analytical biochemistry, 1968, Volume: 22, Issue:2

    Topics: Animals; Brain Chemistry; Catecholamines; Dihydroxyphenylalanine; Dopamine; Epinephrine; Fluorometry; Hydrogen-Ion Concentration; Indoles; Iodine; Methyldopa; Methyltyrosines; Norepinephrine; Normetanephrine; Octopamine; Oxidation-Reduction; Phenethylamines; Rats; Tissue Extracts; Tyramine; Tyrosine

1968
m-Fluorotyrosine convulsions and mortality: relationship to catecholamine and citrate metabolism.
    The Journal of pharmacology and experimental therapeutics, 1967, Volume: 155, Issue:1

    Topics: 5-Hydroxytryptophan; Amphetamine; Animals; Anticonvulsants; Atropine; Azoles; Brain; Chlordiazepoxide; Chlorpromazine; Citrates; Dihydroxyphenylalanine; Disulfiram; Drug Antagonism; Drug Synergism; Kidney; Lysergic Acid Diethylamide; Male; Methyldopa; Mice; Morphine; Nialamide; Norepinephrine; Pargyline; Phenobarbital; Phenytoin; Reserpine; Seizures; Serotonin; Strychnine; Tetrabenazine; Trimethadione; Tyrosine; Urea

1967
Effect of analogs of phenylalanine and tryptophan on kinetics of DOPA decarboxylase in rat brain.
    Brain research, 1966, Volume: 2, Issue:4

    Topics: 5-Hydroxytryptophan; Animals; Brain; Carbon Isotopes; Dihydroxyphenylalanine; Dopa Decarboxylase; Hydrogen-Ion Concentration; Kinetics; Male; Methyldopa; Phenylalanine; Pyridoxal Phosphate; Rats; Tryptophan; Tyrosine

1966
[Autoradiographic study of the basal clear cell in the gastric gland].
    Archivum histologicum Japonicum = Nihon soshikigaku kiroku, 1967, Volume: 28, Issue:3

    Topics: 5-Hydroxytryptophan; Animals; Autoradiography; Chromium; Dihydroxyphenylalanine; Gastric Mucosa; Histocytochemistry; Injections, Intraperitoneal; Injections, Subcutaneous; Male; Methyldopa; Mice; Rats; Reserpine; Serotonin; Silver; Tryptophan; Tyrosine

1967
Studies on urinary phenolic compounds in man. I. Excretion of p-hydroxy-mandelic acid by man.
    Scandinavian journal of clinical and laboratory investigation, 1965, Volume: 17, Issue:5

    Topics: Amino Acid Metabolism, Inborn Errors; Chromatography; Disulfiram; Humans; In Vitro Techniques; Mandelic Acids; Methyldopa; Neuroblastoma; Octopamine; Phenelzine; Phenylketonurias; Thyroxine; Triiodothyronine; Tyrosine; Urine

1965
Effect of alpha-methyltyrosine on stress-induced changes in seizure susceptibility.
    European journal of pharmacology, 1970, Volume: 9, Issue:2

    Topics: Animals; Brain Chemistry; Catecholamines; Chlorpromazine; Disulfiram; Male; Methyldopa; Methyltyrosines; Mice; Monoamine Oxidase Inhibitors; Phenylalanine; Reserpine; Seizures; Stress, Physiological; Tetrabenazine; Time Factors; Tyrosine

1970
Clinical anomalies in patients with schizophrenia.
    Experimental medicine and surgery, 1970, Volume: 28, Issue:3

    Topics: Ascorbic Acid; Chronic Disease; Dopamine; Humans; Metabolism, Inborn Errors; Methyldopa; Schizophrenia; Thalamus; Tyrosine

1970
Depression of behavior and the brain content of alpha-methylnorepinephrine and alpha-methyldopamine following the administration of alpha-methyldopa.
    Neuropharmacology, 1971, Volume: 10, Issue:1

    Topics: Animals; Behavior, Animal; Brain Chemistry; Carbon Isotopes; Catecholamines; Dopamine; Locomotion; Male; Methods; Methyldopa; Normetanephrine; Rats; Tyrosine

1971
The effect of alpha-methyldopa and ultraviolet irradiation on melanogenesis.
    Dermatologica, 1968, Volume: 136, Issue:2

    Topics: Adult; Chromatophores; Humans; Male; Melanins; Methyldopa; Middle Aged; Radiation Effects; Tyrosine; Ultraviolet Rays

1968
Influence of cold exposure on catecholamine depleting actions of hydroxylase inhibitors.
    European journal of pharmacology, 1968, Volume: 3, Issue:1

    Topics: Adaptation, Physiological; Adrenal Glands; Adrenal Medulla; Adrenalectomy; Animals; Cold Temperature; Epinephrine; Liver; Male; Methyldopa; Methyltyrosines; Mixed Function Oxygenases; Myocardium; Norepinephrine; Phenylalanine; Rats; Spleen; Time Factors; Tyrosine

1968
Inhibition of iodotyrosine formation by analogs of tyrosine.
    The Journal of laboratory and clinical medicine, 1969, Volume: 74, Issue:2

    Topics: Animals; Cattle; Chemical Phenomena; Chemistry; Chromatography; Culture Techniques; Humans; Iodine; Iodine Isotopes; Methane; Methyldopa; Monoiodotyrosine; Protein Binding; Thyroid Gland; Thyroid Hormones; Tyrosine

1969
Behavioral effects of L-alpha-methyltyrosine, an inhibitor of tyrosine hydroxylase.
    Life sciences, 1965, Volume: 4, Issue:10

    Topics: Amphetamine; Animals; Avoidance Learning; Behavior, Animal; Brain Chemistry; Chlorpromazine; Dopamine; Enzymes; Methyldopa; Methyltyrosines; Mixed Function Oxygenases; Nialamide; Norepinephrine; Pargyline; Rats; Serotonin; Tranylcypromine; Tyrosine

1965
Suppression, by alpha-methyl-DOPA and alpha-methyl-p-tyrosine, of the anti-inflammatory action of aminopyrine.
    Helvetica physiologica et pharmacologica acta, 1965, Volume: 23, Issue:3

    Topics: Aminopyrine; Animals; Enzymes; Methyldopa; Methyltyrosines; Pleurisy; Rats; Turpentine; Tyrosine

1965
Formation of amines in the gastric mucosa of the rat.
    Nature, 1965, Nov-20, Volume: 208, Issue:5012

    Topics: Animals; Dopa Decarboxylase; Dopamine; Enzymes; Gastric Mucosa; Methyldopa; Rats; Serotonin; Tyrosine

1965
Demonstration of metaraminol in nervous and non-nervous tissues by a histochemical fluorescence reaction.
    Biochemical pharmacology, 1965, Volume: 14, Issue:12

    Topics: Animals; Brain; Fluorescence; In Vitro Techniques; Iris; Metaraminol; Methyldopa; Neurochemistry; Rats; Reserpine; Sympathetic Nervous System; Tongue; Tyrosine

1965
Presence of alpha-methyl-DOPA metabolites in heart and brain of guinea pigs treated with alpha-methyl-tyrosine.
    Life sciences, 1965, Volume: 4, Issue:23

    Topics: Animals; Brain; Catecholamines; Enzymes; Fluorometry; Guinea Pigs; Heart; In Vitro Techniques; Methyldopa; Methyltyrosines; Myocardium; Norepinephrine; Tyrosine

1965
[Comparative studies on the hypotensive action of alpha-methyldopa and alpha-methyl-m-tyrosine].
    Deutsche medizinische Wochenschrift (1946), 1966, Feb-04, Volume: 91, Issue:5

    Topics: Humans; Hypertension; Hypotension, Orthostatic; Methyldopa; Tyrosine

1966
Some experiments in the chemistry of normal sleep.
    The British journal of psychiatry : the journal of mental science, 1966, Volume: 112, Issue:485

    Topics: Arousal; Attention; Brain; Electroencephalography; Eye Movements; Humans; Methionine; Methyldopa; Methysergide; Serotonin; Sleep; Tryptophan; Tyrosine; Urine

1966
The effect of stimulation of sympathetic nerves in the cat treated with reserpine, alpha-methyldopa and alpha-methylmetatyrosine.
    British journal of pharmacology and chemotherapy, 1966, Volume: 26, Issue:1

    Topics: Animals; Blood Pressure; Cats; Heart Conduction System; Heart Rate; Methyldopa; Nictitating Membrane; Norepinephrine; Piperazines; Reserpine; Sympathetic Nervous System; Sympathomimetics; Tyramine; Tyrosine

1966
The mechanism of action of anticonvulsants. II. Acetazolamide.
    Life sciences, 1966, Volume: 5, Issue:8

    Topics: Acetazolamide; Animals; Dextroamphetamine; Dihydroxyphenylalanine; Electric Stimulation; Electroshock; Enzymes; Male; Methyldopa; Mice; Reserpine; Seizures; Stress, Physiological; Tyrosine

1966
The effect of the optical isomers of alpha-methyl-p-tyrosine upon brain and heart catecholamines in the mouse.
    Biochemical pharmacology, 1966, Volume: 15, Issue:5

    Topics: Animals; Brain; Carbon Isotopes; Catecholamines; Dihydroxyphenylalanine; Enzymes; Female; Methyldopa; Methyltyrosines; Mice; Myocardium; Norepinephrine; Tritium; Tyrosine

1966
Effects of epinephrine and chemically related compounds on enzymatic deiodination of thyroxine, triiodothyronine, monoiodotyrosine and diiodotyrosine in vitro.
    Metabolism: clinical and experimental, 1966, Volume: 15, Issue:8

    Topics: Animals; Diiodotyrosine; Ephedrine; Epinephrine; In Vitro Techniques; Iodine; Liver; Methyldopa; Muscles; Norepinephrine; Phenethylamines; Rats; Sympathomimetics; Thyroxine; Triiodothyronine; Tyrosine

1966
A study of central adrenergic mechanisms in the regulation of the oestrous cycle of albino mice.
    British journal of pharmacology and chemotherapy, 1966, Volume: 26, Issue:3

    Topics: Animals; Catecholamines; Estrus; Female; Imipramine; Methyldopa; Methyltyrosines; Mice; Monoamine Oxidase Inhibitors; Pregnancy; Sensory Receptor Cells; Sympathetic Nervous System; Tyrosine

1966
Blockade of release of growth hormone by brain norepinephrine depletors.
    Endocrinology, 1967, Volume: 80, Issue:3

    Topics: Animals; Blood Glucose; Drug Antagonism; Enzymes; Epiphyses; Female; Growth Hormone; Guanethidine; Hypothalamus; Insulin; Iproniazid; Methyldopa; Methyltyrosines; Neurosecretion; Norepinephrine; Rats; Reserpine; Serotonin; Tetrabenazine; Tyramine; Tyrosine

1967
Inhibition of aromatic amino acid decarboxylase and depletion of biogenic amines in brain of rats treated with alpha-monofluoromethyl p-tyrosine: similitudes and differences with the effects of alpha-monofluoromethyldopa.
    Biochemical pharmacology, 1984, Jan-15, Volume: 33, Issue:2

    Topics: Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Biogenic Amines; Brain Chemistry; Kidney; Male; Methyldopa; Methyltyrosines; Rats; Rats, Inbred Strains; Swine; Tyrosine

1984
Thiol compounds. III Synthesis and antihypertensive activity of mercaptoacylamino acids.
    Chemical & pharmaceutical bulletin, 1981, Volume: 29, Issue:5

    Topics: Amino Acids; Animals; Antihypertensive Agents; Dihydroxyphenylalanine; Methyldopa; Phenylalanine; Sulfhydryl Compounds; Tyrosine

1981
Cerebral decarboxylation of meta- and para-tyrosine.
    Experientia, 1983, Feb-15, Volume: 39, Issue:2

    Topics: Animals; Carboxy-Lyases; Corpus Striatum; Dose-Response Relationship, Drug; Homovanillic Acid; Male; Methyldopa; Mice; Tyramine; Tyrosine

1983
Quantitative microdialysis for studying the in vivo L-DOPA kinetics in blood and skeletal muscle of the dog.
    Pharmaceutical research, 1995, Volume: 12, Issue:5

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Blood Proteins; Calibration; Dialysis; Dogs; Dopamine; Injections, Intramuscular; Injections, Intravenous; Levodopa; Male; Methyldopa; Microchemistry; Muscle, Skeletal; Protein Binding; Reference Standards; Reproducibility of Results; Tyrosine

1995
The effects of alpha-methyl-DOPA and alpha-methyl-metatyrosine on the metabolism of norepinephrine and serotonin in vivo.
    The Journal of pharmacology and experimental therapeutics, 1961, Volume: 134

    Topics: Dihydroxyphenylalanine; Methyldopa; Methyltyrosines; Norepinephrine; Serotonin; Tyrosine

1961
INHIBITORY EFFECTS OF DECARBOXYLASE INHIBITORS ON THE METABOLISM OF TYROSINE-C14 IN THE RAT.
    Canadian journal of biochemistry and physiology, 1963, Volume: 41

    Topics: Amino Acids; Carbon Dioxide; Carbon Isotopes; Carboxy-Lyases; Enzyme Inhibitors; Methyldopa; Pharmacology; Proteins; Rats; Research; Tyrosine; Tyrosine Decarboxylase

1963
[TRIALS OF A NEW ANTIHYPERTENSIVE, ALPHA-METHYL-DOPA (ALDOMET) WITH SPECIAL REFERENCE TO CHANGES IN RETINAL BLOOD FLOW].
    Rinsho ganka. Japanese journal of clinical ophthalmology, 1963, Volume: 17

    Topics: Angiotensins; Antihypertensive Agents; Blood Circulation; Blood Pressure; Blood Pressure Determination; Dopamine; Epinephrine; Hemodynamics; Methyldopa; NAD; Norepinephrine; Phenylalanine; Renin; Retinal Vessels; Serotonin; Tryptophan; Tyrosine

1963
STUDIES ON MORPHINE. III. ACTION OF METABOLIC PRECURSORS TO SEROTONIN AND NORADRENALINE AND RELATED SUBSTANCES ON THE "ABSTINENCE SYNDROME" TO MORPHINE ON WHITE MICE.
    Archives internationales de pharmacodynamie et de therapie, 1963, Dec-01, Volume: 146

    Topics: Brain; Catecholamines; Dihydroxyphenylalanine; Ergot Alkaloids; Iproniazid; Kynurenine; Lysergic Acid Diethylamide; Methyldopa; Mice; Morphine; Nalorphine; Norepinephrine; ortho-Aminobenzoates; Pharmacology; Phenylalanine; Research; Serotonin; Shikimic Acid; Toxicology; Tryptophan; Tyrosine

1963
INHIBITION OF THE HYDROXYLATION OF TRYPTOPHAN AND PHENYLALANINE BY ALPHA-METHYL-DOPA AND SIMILAR COMPOUNDS.
    Life sciences (1962), 1964, Volume: 3

    Topics: Antihypertensive Agents; Carboxy-Lyases; Enzyme Inhibitors; Hydroxylation; Liver; Metabolism; Methyldopa; Mixed Function Oxygenases; Pharmacology; Phenylalanine; Rats; Research; Research Design; Tissue Culture Techniques; Tryptophan; Tyrosine

1964
EFFECTS OF ALPHA-METHYL-META-TYROSINE INTRAVENOUSLY IN MAN.
    Life sciences (1962), 1964, Volume: 3

    Topics: Antihypertensive Agents; Blood Pressure Determination; Humans; Injections; Injections, Intravenous; Male; Methyldopa; Methyltyrosines; Tyrosine

1964
STUDIES ON THE SPECIFICITY OF TYROSINE-ALPHA-KETOGLUTARATE TRANSAMINASE.
    The Journal of biological chemistry, 1964, Volume: 239

    Topics: 5-Hydroxytryptophan; Alanine; Amphetamine; Benzoates; Butyrates; Catecholamines; Dihydroxyphenylalanine; Enzyme Inhibitors; Ephedrine; Indoleacetic Acids; Ketoglutaric Acids; Lactates; Liver; Mandelic Acids; Methyldopa; Normetanephrine; Pharmacology; Phenylacetates; Phenylalanine; Propionates; Rats; Research; Transaminases; Tryptophan; Tyramine; Tyrosine; Tyrosine Transaminase

1964
ON THE MECHANISM OF EMESIS INDUCED BY 5-HYDROXYTRYPTAMINE.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1964, Volume: 116

    Topics: Brain Chemistry; Cats; Chlorpromazine; Iproniazid; Isocarboxazid; Methyldopa; Monoamine Oxidase Inhibitors; Nialamide; Pentobarbital; Pharmacology; Research; Reserpine; Serotonin; Toxicology; Tyrosine; Vomiting

1964
[5-HYDROXYTRYPTOPHAN DOPA DECARBOXYLASE IN NERVOUS AND CARDIAC TISSUES IN THE MOLLUSC HELIX POMATIA. INTERACTION OF SUBSTRATES IN VITRO].
    Comptes rendus hebdomadaires des seances de l'Academie des sciences, 1964, Jul-27, Volume: 259

    Topics: 5-Hydroxytryptophan; Aromatic-L-Amino-Acid Decarboxylases; Dihydroxyphenylalanine; Dopa Decarboxylase; Heart; In Vitro Techniques; Methyldopa; Mollusca; Myocardium; Nerve Tissue; Physiology, Comparative; Research; Serotonin; Tryptophan; Tyrosine

1964
ON THE MECHANISM OF NORADRENALINE DEPLETION BY ALPHA-METHYL METATYROSINE AND METARAMINOL.
    Acta pharmacologica et toxicologica, 1964, Volume: 21

    Topics: Animals; Basal Ganglia; Brain Chemistry; Brain Stem; Cerebellum; Dopamine; Ganglia; Heart; Metaraminol; Methyldopa; Methyltyrosines; Norepinephrine; Pharmacology; Rabbits; Rats; Research; Tyramine; Tyrosine

1964
MULTIPLE INHIBITORY EFFECTS OF ALPHA-METHYLAMINO ACIDS ON THE METABOLISM OF C14-LABELED TYROSINE, DOPA AND ALPHA-METHYLDOPA.
    The Journal of pharmacology and experimental therapeutics, 1965, Volume: 148

    Topics: Amino Acid Oxidoreductases; Amino Acids; Carbon Isotopes; Carboxy-Lyases; D-Amino-Acid Oxidase; Dihydroxyphenylalanine; Enzyme Inhibitors; Metabolism; Methyldopa; Pharmacology; Radiometry; Rats; Research; Tyrosine

1965
EFFECT OF CATECHOLAMINE PRECURSORS AND PHENYLETHYLAMINES ON SPONTANEOUS ACTIVITY AND ON THE RESPONSE TO METHOHEXITAL ANAESTHESIA.
    Canadian Anaesthetists' Society journal, 1965, Volume: 12

    Topics: Amphetamine; Amphetamines; Anesthesia; Anesthetics; Animals; Arousal; Behavior, Animal; Catecholamines; Dihydroxyphenylalanine; Dopamine; Electroencephalography; Hypnosis; Hypnosis, Anesthetic; Methohexital; Methyldopa; Phenethylamines; Psychopharmacology; Rats; Research; Tyramine; Tyrosine

1965
Reactions of D-glucose with phenolic amino acids: further insights into the competition between Maillard and Pictet-Spengler condensation pathways.
    Carbohydrate research, 2005, Dec-30, Volume: 340, Issue:18

    Topics: Catalysis; Cysteinyldopa; Glucose; Hydrogen-Ion Concentration; Maillard Reaction; Metals, Heavy; Methyldopa; Molecular Conformation; Stereoisomerism; Tyrosine

2005
Enantioseparation of dopa and related compounds by cyclodextrin-modified microemulsion electrokinetic chromatography.
    Journal of chromatography. A, 2008, Sep-19, Volume: 1204, Issue:2

    Topics: Amino Acids, Aromatic; Chromatography; Chromatography, Micellar Electrokinetic Capillary; Cyclodextrins; Dihydroxyphenylalanine; Hydrogen-Ion Concentration; Methyldopa; Phenylalanine; Reproducibility of Results; Stereoisomerism; Tyrosine

2008