methyldopa has been researched along with nordefrin in 27 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 26 (96.30) | 18.7374 |
| 1990's | 1 (3.70) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Werner, U | 1 |
| Buckley, JP; Jandhyala, BS; Lokhandwala, MF | 1 |
| Bolme, P; Forsyth, RP; Ishizaki, T; Melmon, KL | 1 |
| van Zwieten, AP | 1 |
| Frankel, RJ; Ganong, WF; Reid, IA | 1 |
| Ames, MM; Castagnoli, N; Melmon, KL | 1 |
| De Jong, W; Nijkamp, FP | 1 |
| Freed, CR; Murphy, RC; Quintero, E | 1 |
| Conway, EL; Jarrott, B; Louis, WJ | 1 |
| Abe, K; Aoyagi, H; Chiba, S; Irokawa, N; Kusaka, T; Miyazaki, S; Otsuka, Y; Saito, K; Sakurai, Y; Seino, M; Yasujima, M; Yoshinaga, K | 1 |
| Henning, M | 1 |
| Altura, BM | 1 |
| Chen, SZ; Hsu, CH; Tseng, CJ; Tung, CS | 1 |
| Goldberg, MR; Hollister, AS; Robertson, D; Sweetman, BJ; Tung, CS | 1 |
| Bobik, A; Mill, GK; Oddie, CJ; Scott, PJ | 1 |
| Clineschmidt, BV; Faison, EP; Flataker, LM; Haubrich, DR | 1 |
| Goldberg, MR; Hollister, AS; Oates, JA; Robertson, D; Tung, CS | 1 |
| Bobik, A; Jackman, GP; Oddie, CJ; Skews, H | 1 |
| Hu, GY; Ji, XQ; Yi, QC; Zhao, DD; Zou, G | 1 |
| Fernstrom, JD; Sved, AF; Wiggins, JF | 1 |
| Fujita, Y; Kawano, T; Maemura, S; Niwa, M; Ozaki, M | 1 |
| Dougan, DF; Duffield, AM; Duffield, PH; Wade, DN | 1 |
| Mwaluko, G; Weinshilboum, R | 1 |
| Gantenberg, NS; Járai, Z; Kunos, G; Lazar-Wesley, E; Li, SJ; Scanlon, MN; Varga, K | 1 |
| MAITRE, L; MUSCHOLL, E | 1 |
| DAY, MD; RAND, MJ | 1 |
| CARLSSON, A; DAHLSTROEM, A; FUXE, K; HILLARP, NA | 1 |
1 review(s) available for methyldopa and nordefrin
| Article | Year |
|---|---|
Central sympathetic transmitters and hypertension.
Topics: Acetylcholine; Animals; Blood Pressure; Cardiac Output; Cats; Clonidine; Dihydroxyphenylalanine; Dogs; Heart Rate; Humans; Hypertension; Methyldopa; Nordefrin; Norepinephrine; Rabbits; Rats; Serotonin | 1975 |
1 trial(s) available for methyldopa and nordefrin
| Article | Year |
|---|---|
Interaction of dopamine, methyldopa and reserpine in the sympatho-adrenal system in essential hypertension.
Topics: Adult; Dopamine; Dose-Response Relationship, Drug; Drug Synergism; Humans; Hypertension; Methyldopa; Middle Aged; Nordefrin; Reserpine; Urine | 1976 |
25 other study(ies) available for methyldopa and nordefrin
| Article | Year |
|---|---|
[An improved trihydroxyindole method for the determination of urinary catecholamines].
Topics: Chromatography, Ion Exchange; Copper; Epinephrine; Humans; Hydrogen-Ion Concentration; Hypertension; Indoles; Methyldopa; Nordefrin; Norepinephrine; Pheochromocytoma | 1975 |
Studies on the mechanism of the cardiovascualr effects of methyldopa.
Topics: Animals; Blood Pressure; Cardiac Output; Dogs; Female; Ganglionic Blockers; Heart Rate; Hemodynamics; Kidney; Male; Mesenteric Arteries; Methyldopa; Nordefrin; Norepinephrine; Sympathetic Nervous System | 1976 |
Hemodynamic effects of systemic and central administration of alpha-methyldopa.
Topics: Animals; Dopamine; Female; Haplorhini; Hemodynamics; Infusions, Parenteral; Injections, Intraventricular; Macaca mulatta; Male; Methyldopa; Nordefrin; Norepinephrine; Time Factors | 1978 |
Antihypertensive action of clonidine (Catapresan).
Topics: Animals; Blood Pressure; Bradycardia; Brain Stem; Cats; Clonidine; Depression, Chemical; Drug Evaluation; Humans; Hypertension; Methyldopa; Nordefrin; Receptors, Adrenergic, alpha; Stimulation, Chemical; Sympathetic Nervous System | 1977 |
Role of central and peripheral mechanisms in the action of alpha-methyldopa on blood pressure and renin secretion.
Topics: Animals; Blood Pressure; Carbidopa; Depression, Chemical; Dogs; Drug Interactions; Female; Infusions, Parenteral; Injections, Intraventricular; Male; Methyldopa; Nordefrin; Renin; Time Factors | 1977 |
Stereochemical course in vivo of alpha-methyldopa decarboxylation in rat brains.
Topics: Amino Acids; Animals; Brain; Caudate Nucleus; Decarboxylation; Deoxyepinephrine; Dopamine; Hypothalamus; Male; Mass Spectrometry; Methyldopa; Nordefrin; Norepinephrine; Rats; Stereoisomerism | 1977 |
Centrally induced hypotension by alpha-methyldopa and alpha-methylnoradrenaline in normotensive and renal hypertensive rats.
Topics: Animals; Blood Pressure; Brain; Dogs; Heart Rate; Hypertension, Renal; Methyldopa; Nordefrin; Norepinephrine; Rats | 1977 |
Hypotension and hypothalamic amine metabolism after long-term alpha-methyldopa infusions.
Topics: Amines; Animals; Blood Pressure; Hypothalamus; Infusions, Parenteral; Male; Methyldopa; Nordefrin; Rats; Time Factors | 1978 |
The effect of acute alpha-methyldopa administration on catecholamine levels in anterior hypothalamic-preoptic and medullary nuclei in rat brain.
Topics: Animals; Catecholamines; Hypothalamus; Hypothalamus, Anterior; Male; Medulla Oblongata; Methyldopa; Nordefrin; Preoptic Area; Rats; Time Factors | 1979 |
Pharmacological effects of alpha-methyldopa, alpha-methylnorepinephrine, and octopamine on rat arteriolar, arterial, and terminal vascular smooth.
Topics: Administration, Topical; Animals; Aorta, Thoracic; Blood Vessels; Dopamine; Dose-Response Relationship, Drug; Epinephrine; In Vitro Techniques; Injections, Intra-Arterial; Injections, Intraperitoneal; Male; Mesenteric Arteries; Methyldopa; Muscle Contraction; Muscle, Smooth; Nordefrin; Norepinephrine; Octopamine; Phenylephrine; Rats; Structure-Activity Relationship; Vasomotor System | 1975 |
Limitation of the alpha-methylnorepinephrine hypothesis in the hypotensive effect of alpha-methyldopa.
Topics: Animals; Blood Pressure; Brain; Chromatography, High Pressure Liquid; Consciousness; Electrochemistry; Kinetics; Male; Methyldopa; Models, Cardiovascular; Nordefrin; Norepinephrine; Osmolar Concentration; Peripheral Nerves; Rats; Rats, Inbred Strains | 1989 |
Depletion of brainstem epinephrine stores by alpha-methyldopa: possible relation to attenuated sympathetic outflow.
Topics: Adrenal Glands; Animals; Brain Stem; Chromatography, Liquid; Dopamine; Epinephrine; Gas Chromatography-Mass Spectrometry; Male; Methyldopa; Myocardium; Nordefrin; Norepinephrine; Rats; Rats, Inbred Strains | 1988 |
High-performance liquid chromatographic analysis of norepinephrine and alpha-methylnorepinephrine in microdissected noradrenergic cell groups of the rabbit brain.
Topics: Animals; Brain; Brain Chemistry; Catecholamines; Chromatography, High Pressure Liquid; Histocytochemistry; In Vitro Techniques; Indicators and Reagents; Methyldopa; Nordefrin; Norepinephrine; Rabbits; Spectrometry, Fluorescence | 1986 |
alpha-methyldopa reduces locomotor activity in rats via its metabolite, alpha-methylnorepinephrine, acting on alpha 2-adrenoceptors.
Topics: Animals; Clonidine; Depression, Chemical; Dose-Response Relationship, Drug; Drug Antagonism; Female; Methyldopa; Motor Activity; Nordefrin; Norepinephrine; Prazosin; Rats; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Yohimbine | 1980 |
Central and peripheral cardiovascular effects of alpha-methylepinephrine.
Topics: Animals; Blood Pressure; Epinephrine; Heart Rate; Male; Methyldopa; Nordefrin; Rats; Rats, Inbred Strains | 1983 |
High-performance liquid chromatographic determination of plasma catecholamines during alpha-methyldopa therapy.
Topics: Animals; Catecholamines; Chromatography, High Pressure Liquid; Epinephrine; Humans; Hypertension; Methyldopa; Nordefrin; Norepinephrine; Rabbits; Species Specificity | 1984 |
[The role of noradrenergic neurons in morphine analgesia (author's transl)].
Topics: Analgesia; Animals; Methyldopa; Morphine; Neurons; Nordefrin; Norepinephrine; Rats; Sympathetic Nervous System | 1980 |
Effects of alpha-methyldopa and its metabolites on prolactin release: in vivo and in vitro studies.
Topics: Animals; Deoxyepinephrine; Dopamine; Haloperidol; In Vitro Techniques; Male; Methyldopa; Nordefrin; Pituitary Gland; Prolactin; Rats; Receptors, Dopamine; Thyrotropin-Releasing Hormone; Time Factors | 1980 |
[Alpha-methyldopa and brain monoamines].
Topics: Animals; Antihypertensive Agents; Biotransformation; Brain; Catecholamines; Dihydroxyphenylalanine; Female; Gestational Age; Hypertension; Male; Methyldopa; Neurons; Nordefrin; Pregnancy; Rats; Rats, Inbred Strains; Spinal Cord; Sympathectomy, Chemical | 1982 |
Absence of alpha-methyldopamine in rat striatum after chronic administration of d-amphetamine.
Topics: alpha-Methyltyrosine; Animals; Chromatography, Gas; Corpus Striatum; Decarboxylation; Deoxyepinephrine; Dextroamphetamine; Dopamine; Male; Methyldopa; Methyltyrosines; Nordefrin; p-Hydroxyamphetamine; Rats; Time Factors | 1982 |
alpha-Methyldopa, alpha-methyldopamine an alpha-methylnoradrenaline: substrates for the thermolabile form of human platelet phenol sulphotransferase.
Topics: Arylsulfotransferase; Blood Platelets; Deoxyepinephrine; Dopamine; Hot Temperature; Humans; Hydrogen-Ion Concentration; In Vitro Techniques; Kinetics; Methyldopa; Nordefrin; Norepinephrine; Sulfurtransferases | 1982 |
alpha-2-Adrenergic activation of proopiomelanocortin-containing neurons in the arcuate nucleus causes opioid-mediated hypotension and bradycardia.
Topics: Adrenergic alpha-Agonists; Animals; Arcuate Nucleus of Hypothalamus; beta-Endorphin; Bradycardia; Hypotension; In Situ Hybridization; Male; Methyldopa; Microinjections; Neurons; Nordefrin; Pro-Opiomelanocortin; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha; RNA, Messenger; Yohimbine | 1996 |
RELEASE BY SYMPATHETIC STIMULATION OF ALPHA-METHYLNORADRENALINE STORED IN THE HEART AFTER ADMINISTRATION OF ALPHA-METHYLDOPA.
Topics: Animals; Catecholamines; Ganglionic Blockers; Heart; Methyldopa; Nordefrin; Norepinephrine; Perfusion; Pharmacology; Piperazines; Rabbits; Research; Selective Serotonin Reuptake Inhibitors; Serotonin; Sympathetic Nervous System | 1963 |
SOME OBSERVATIONS ON THE PHARMACOLOGY OF ALPHA-METHYLDOPA.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Carotid Sinus; Cats; Deoxyepinephrine; Dihydroxyphenylalanine; Dogs; Dopamine; Guinea Pigs; Humans; Ileum; Lagomorpha; Male; Methyldopa; Nictitating Membrane; Nordefrin; Norepinephrine; Pharmacology; Pressoreceptors; Rabbits; Rats; Research; Reserpine; Spleen; Sympathetic Nervous System; Tyramine; Vas Deferens | 1964 |
FAILURE OF RESERPINE TO DEPLETE NORADRENALINE NEURONS OF ALPHA-METHYLNORADRENALINE FORMED FROM ALPHA-METHYL DOPA.
Topics: Basal Ganglia; Brain; Catecholamines; Caudate Nucleus; Dopamine; Fluorescence; Ganglia; Histocytochemistry; Hypothalamus; Methyldopa; Neurons; Nordefrin; Norepinephrine; Pharmacology; Rats; Research; Reserpine; Spinal Cord | 1965 |