methyldopa has been researched along with morphine in 30 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 19 (63.33) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (13.33) | 29.6817 |
| 2010's | 7 (23.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Campillo, NE; Guerra, A; Páez, JA | 1 |
| García-Mera, X; González-Díaz, H; Prado-Prado, FJ | 1 |
| Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K | 1 |
| Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY | 1 |
| Bellman, K; Knegtel, RM; Settimo, L | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Cox-van Put, J; de Jong, W; Sandor, P; van den Berg, MH; van Giersbergen, PL | 1 |
| Bergmann, F; Chaimovitz, M; Pasternak, V; Ramu, A | 1 |
| Mennear, JH; Rudzik, AD | 1 |
| Contreras, E; Tamayo, L | 1 |
| Ashford, A; Ross, JW | 1 |
| Contreras, E; Quijada, L; Tamayo, L | 2 |
| Afrikanov, II; Vedernikov, YP | 1 |
| Aihara, H; Kasai, A; Sakai, T | 1 |
| Deneau, GA; Seevers, MH; Segal, M | 1 |
| Spoerlein, MT; Vander Wende, C | 1 |
| Koe, BK; Weissman, A | 1 |
| Gunne, LM | 1 |
| Nijkamp, FP; Sitsen, JM | 1 |
| Farsang, C; Kunos, G; Mucci, L; Ramirez-Gonzalez, MD | 1 |
| Forman, LJ; Meites, J; Miki, N; Ramos, T; Sonntag, WE | 1 |
| Hu, GY; Ji, XQ; Yi, QC; Zhao, DD; Zou, G | 1 |
| TSOU, K; TU, ZH | 1 |
| CONTRERAS, E; CROXATTO, R; HUIDOBRO, F | 1 |
1 review(s) available for methyldopa and morphine
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
29 other study(ies) available for methyldopa and morphine
| Article | Year |
|---|---|
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical | 2010 |
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics | 2010 |
QSAR-based permeability model for drug-like compounds.
Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2011 |
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding | 2012 |
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation | 2014 |
Beta-endorphin and central control of arterial blood pressure during challenge of circulatory homeostasis.
Topics: Animals; beta-Endorphin; Blood Pressure; Blood Volume; Bloodletting; Dose-Response Relationship, Drug; Endorphins; Homeostasis; Male; Methyldopa; Morphine; Naloxone; Rats; Rats, Inbred Strains; Shock | 1989 |
Compulsive gnawing in rats after implantation of drugs into the ventral thalamus. A contribution to the mechanism of morphine action.
Topics: Amphetamine; Animals; Apomorphine; Brain; Chlorpromazine; Compulsive Behavior; Corpus Striatum; Disulfiram; Dose-Response Relationship, Drug; Drug Synergism; Fenclonine; Haloperidol; Humans; Meperidine; Methadone; Methyldopa; Methyltyrosines; Morphine; Nalorphine; Phenoxybenzamine; Phentolamine; Pimozide; Rats; Thalamus | 1974 |
Antagonism of analgesics by amine-depleting agents.
Topics: Animals; Aspirin; Biological Assay; Catecholamines; Methyldopa; Mice; Morphine; Reserpine; Tyrosine | 1965 |
Effects of drugs acting in relation to sympathetic functions on the analgesic action of morphine.
Topics: Animals; Bretylium Compounds; Dibenzylchlorethamine; Dopamine; Drug Antagonism; Epinephrine; Ethanolamines; Female; Guanethidine; Male; Methamphetamine; Methyldopa; Methyltyrosines; Morphine; Norepinephrine; Phenoxybenzamine; Pyrogallol; Rats; Reserpine; Tolazoline; Tyramine | 1966 |
The effect of reserpine and alpha-methyldopa on the analgesic action of morphine in the mouse.
Topics: Analgesia; Animals; Drug Antagonism; Drug Synergism; Hot Temperature; Male; Methyldopa; Mice; Morphine; Pain; Reserpine | 1967 |
Effect of nialamide and methyldopa on the analgesic action of morphine in rats and mice.
Topics: Analgesia; Animals; Drug Synergism; Electric Stimulation; Male; Methyldopa; Mice; Morphine; Nialamide; Rats; Reaction Time | 1969 |
On the role of a central adrenergic mechanism in morphine analgesic action.
Topics: Amphetamine; Animals; Brain; Cocaine; Disulfiram; Drug Synergism; Female; Iproniazid; Methyldopa; Morphine; Norepinephrine; Pyrogallol; Rats; Reserpine; Tryptophan | 1969 |
The effect of dopamine on peripheral vasculature of the rat.
Topics: Animals; Blood Pressure; Blood Vessels; Cocaine; Constriction; Depression, Chemical; Disulfiram; Dopamine; Dopamine Antagonists; Drug Synergism; Ephedrine; Ergotamine; Haloperidol; Hindlimb; Kidney; Male; Methyldopa; Morphine; Norepinephrine; Perfusion; Propranolol; Rats; Reserpine; Stimulation, Chemical; Tyramine | 1972 |
Levels and distribution of central nervous system amines in normal and morphine-dependent monkeys.
Topics: Animals; Behavior, Animal; Brain Chemistry; Caudate Nucleus; Cerebellum; Cerebral Cortex; Dopamine; Haplorhini; Humans; Hypothalamus; Iproniazid; Macaca; Medulla Oblongata; Mesencephalon; Methyldopa; Morphine; Norepinephrine; Pons; Reserpine; Serotonin; Spinal Cord; Substance Withdrawal Syndrome; Substance-Related Disorders; Thalamus; Thebaine | 1972 |
Antagonism by dopa of morphine analgesia. A hypothesis for morphine tolerance.
Topics: Animals; Brain; Brain Chemistry; Dihydroxyphenylalanine; Dopamine; Drug Combinations; Drug Interactions; Drug Tolerance; Male; Methyldopa; Mice; Mice, Inbred Strains; Morphine; Norepinephrine; Serotonin; Time Factors | 1972 |
m-Fluorotyrosine convulsions and mortality: relationship to catecholamine and citrate metabolism.
Topics: 5-Hydroxytryptophan; Amphetamine; Animals; Anticonvulsants; Atropine; Azoles; Brain; Chlordiazepoxide; Chlorpromazine; Citrates; Dihydroxyphenylalanine; Disulfiram; Drug Antagonism; Drug Synergism; Kidney; Lysergic Acid Diethylamide; Male; Methyldopa; Mice; Morphine; Nialamide; Norepinephrine; Pargyline; Phenobarbital; Phenytoin; Reserpine; Seizures; Serotonin; Strychnine; Tetrabenazine; Trimethadione; Tyrosine; Urea | 1967 |
Influence of nalorphine upon the synergistic effect of methyldopa and ergonovine on morphine analgesia.
Topics: Animals; Drug Synergism; Ergonovine; Female; Male; Methyldopa; Morphine; Nalorphine; Pain; Proadifen; Rats | 1967 |
Some pharmacological agents modifying the morphine abstinence syndrome in dogs.
Topics: Animals; Dihydroxyphenylalanine; Dogs; Drug Tolerance; Humans; Methyldopa; Methyltyrosines; Morphine; Nalorphine; Nialamide; Reserpine; Substance Withdrawal Syndrome | 1965 |
Is the hypothermic effect of alpha-methyldopa mediated by opioid peptides?
Topics: Animals; Body Temperature; Endorphins; Male; Methyldopa; Morphine; Naltrexone; Rats; Rats, Inbred Strains | 1984 |
Possible role of an endogenous opiate in the cardiovascular effects of central alpha adrenoceptor stimulation in spontaneously hypertensive rats.
Topics: Anesthesia; Animals; Blood Pressure; Clonidine; Dose-Response Relationship, Drug; Drug Interactions; Endorphins; Heart Rate; Hypertension; Male; Methyldopa; Morphine; Naloxone; Naltrexone; Rats; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Receptors, Opioid; Time Factors; Yohimbine | 1980 |
Comparison of the effects of central acting drugs on prolactin release in young and old male rats.
Topics: Age Factors; Animals; Haloperidol; Male; Methyldopa; Morphine; Naloxone; Prolactin; Quinolines; Quipazine; Radioimmunoassay; Rats | 1981 |
[The role of noradrenergic neurons in morphine analgesia (author's transl)].
Topics: Analgesia; Animals; Methyldopa; Morphine; Neurons; Nordefrin; Norepinephrine; Rats; Sympathetic Nervous System | 1980 |
[EFFECTS OF RESERPINE, ALPHA-METHYL-DOPA AND THEIR INTERACTIONS ON MORPHINE ANALGESIA].
Topics: Analgesia; Animals; Antihypertensive Agents; Catecholamines; Dihydroxyphenylalanine; Electricity; Hot Temperature; Injections; Methyldopa; Mice; Morphine; Pain; Pharmacology; Research; Reserpine; Selective Serotonin Reuptake Inhibitors; Serotonin | 1963 |
STUDIES ON MORPHINE. III. ACTION OF METABOLIC PRECURSORS TO SEROTONIN AND NORADRENALINE AND RELATED SUBSTANCES ON THE "ABSTINENCE SYNDROME" TO MORPHINE ON WHITE MICE.
Topics: Brain; Catecholamines; Dihydroxyphenylalanine; Ergot Alkaloids; Iproniazid; Kynurenine; Lysergic Acid Diethylamide; Methyldopa; Mice; Morphine; Nalorphine; Norepinephrine; ortho-Aminobenzoates; Pharmacology; Phenylalanine; Research; Serotonin; Shikimic Acid; Toxicology; Tryptophan; Tyrosine | 1963 |