methyldopa has been researched along with metoprolol in 32 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 18 (56.25) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (15.63) | 29.6817 |
| 2010's | 8 (25.00) | 24.3611 |
| 2020's | 1 (3.13) | 2.80 |
| Authors | Studies |
|---|---|
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM | 1 |
| Campillo, NE; Guerra, A; Páez, JA | 1 |
| Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
| Avdeef, A; Tam, KY | 1 |
| Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K | 1 |
| Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V | 1 |
| Bellman, K; Knegtel, RM; Settimo, L | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Lund-Johansen, P | 1 |
| Agabiti-Rosei, E; Alicandri, C; Motolese, M; Muiesan, G | 1 |
| Alexandre, JM; Andrejak, M; Caillens, C; Coevoet, B; de Fremont, JF; Fournier, A; Gueris, J; Harichaux, P; Lambrey, G; Makdassi, R; Quichaud, J | 1 |
| Barbour, MP; Hillis, WS; Lawrie, TD; Linden, RJ; Lorimer, AR; Sreeharan, N; Stoker, JB | 1 |
| Berglund, G; Bergstrand, RH; Vedin, JA; Wilhelmsson, CE | 1 |
| Betts, TA; Blake, A; Crowe, A; Harvey, P; Knight, R; Mortiboy, D | 1 |
| Weinshilboum, RM | 1 |
| Johnson, JM | 1 |
| Sandström, B | 1 |
| Condorelli, M; Cuocolo, A; De Luca, N; De Simone, A; Ricciardelli, B; Rosiello, G; Trimarco, B; Veniero, AM; Volpe, M | 1 |
| Hallbäck-Nordlander, MI; Lundin, SA | 1 |
| Lepäntalo, M | 1 |
| Lepäntalo, M; von Knorring, J | 1 |
| Karachalios, GN | 1 |
| Freed, CR; Gerber, JG; Nies, AS | 1 |
| Checchi, M; Galeone, F; Giuntoli, F; Guidi, G; Locci, P; Saba, GC; Saba, P | 1 |
| Agabiti-Rosei, E; Buoninconti, R; Carotti, A; Fariello, R; Innocenti, P; Motolese, M; Muiesan, G; Solinas, E; Toso, M | 1 |
| Barbour, M; Hillis, WS; Lawrie, TD; Leanage, RU; Linden, RJ; Lorimer, AR; Sreeharan, N; Stoker, JB | 1 |
| Ghafarzadeh, M; Namdari, P; Shakarami, A; Yari, F | 1 |
3 review(s) available for methyldopa and metoprolol
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Psychiatric uses of antiadrenergic and adrenergic blocking drugs.
Topics: Adult; Alcohol Amnestic Disorder; Antipsychotic Agents; Bipolar Disorder; Clinical Trials as Topic; Clonidine; Depressive Disorder; Drug Therapy, Combination; Dyskinesia, Drug-Induced; Female; Humans; Male; Mental Disorders; Methyldopa; Metoprolol; Migraine Disorders; Propranolol; Reserpine; Schizophrenia; Substance Withdrawal Syndrome | 1984 |
Antihypertensive pharmacology.
Topics: Adolescent; Adult; Antihypertensive Agents; Clonidine; Diazoxide; Diuretics; Guanethidine; Humans; Hydralazine; Hypertension; Methyldopa; Metoprolol; Minoxidil; Nitroprusside; Patient Compliance; Prazosin; Propranolol; Reserpine; Sodium Chloride Symporter Inhibitors | 1980 |
8 trial(s) available for methyldopa and metoprolol
| Article | Year |
|---|---|
Antihypertensive activity of alpha-methyldopa on a twice daily regimen in comparison to metoprolol. A multi-centre controlled clinical trial.
Topics: Adult; Aged; Blood Pressure; Clinical Trials as Topic; Female; Heart Rate; Humans; Hypertension; Male; Methyldopa; Metoprolol; Middle Aged; Norepinephrine; Placebos; Propanolamines; Renin | 1978 |
Effect of exercise in hypertension controlled with metoprolol or methyldopa.
Topics: Adult; Aged; Blood Pressure; Female; Heart Rate; Humans; Hypertension; Male; Methyldopa; Metoprolol; Middle Aged; Physical Exertion; Propanolamines | 1979 |
Comparative study of metoprolol and alpha-methyldopa in untreated essential hypertension.
Topics: Blood Pressure; Clinical Trials as Topic; Drug Administration Schedule; Drug Evaluation; Heart Rate; Humans; Hypertension; Male; Methyldopa; Metoprolol; Middle Aged; Propanolamines | 1976 |
Psychiatric uses of antiadrenergic and adrenergic blocking drugs.
Topics: Adult; Alcohol Amnestic Disorder; Antipsychotic Agents; Bipolar Disorder; Clinical Trials as Topic; Clonidine; Depressive Disorder; Drug Therapy, Combination; Dyskinesia, Drug-Induced; Female; Humans; Male; Mental Disorders; Methyldopa; Metoprolol; Migraine Disorders; Propranolol; Reserpine; Schizophrenia; Substance Withdrawal Syndrome | 1984 |
Chronic effects of metoprolol and methyldopa on calf blood flow in intermittent claudication.
Topics: Adult; Aged; Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Female; Heart Rate; Humans; Hypertension; Intermittent Claudication; Leg; Male; Methyldopa; Metoprolol; Middle Aged; Regional Blood Flow; Vascular Resistance | 1984 |
Walking capacity of patients with intermittent claudication during chronic antihypertensive treatment with metoprolol and methyldopa.
Topics: Adult; Aged; Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Exercise Test; Female; Heart Rate; Humans; Hypertension; Intermittent Claudication; Locomotion; Male; Methyldopa; Metoprolol; Middle Aged | 1984 |
[Double-blind comparative study of the hypotensive effect of combination therapy with chlorthalidone and metoprolol or alpha-methyldopa].
Topics: Chlorthalidone; Clinical Trials as Topic; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hypertension; Male; Methyldopa; Metoprolol; Middle Aged; Propanolamines | 1981 |
[A comparative evaluation of metoprolol and methyldopa in hypertension therapy (author's transl)].
Topics: Adult; Aged; Blood Pressure; Female; Heart Rate; Humans; Hypertension; Male; Methyldopa; Metoprolol; Middle Aged; Propanolamines; Regression Analysis | 1980 |
22 other study(ies) available for methyldopa and metoprolol
| Article | Year |
|---|---|
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
Topics: | 2008 |
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical | 2010 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
How well can the Caco-2/Madin-Darby canine kidney models predict effective human jejunal permeability?
Topics: Animals; Disease Models, Animal; Dogs; Humans; Jejunal Diseases; Kidney Diseases; Models, Biological; Permeability; Porosity; Regression Analysis | 2010 |
QSAR-based permeability model for drug-like compounds.
Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2011 |
FDA-approved drug labeling for the study of drug-induced liver injury.
Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration | 2011 |
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation | 2014 |
alpha-Methyldopa and beta-blockers in hypertension--a comparison of their haemodynamic effects.
Topics: Adrenergic beta-Antagonists; Alprenolol; Hemodynamics; Humans; Hypertension; Methyldopa; Metoprolol; Physical Exertion; Propranolol; Time Factors; Timolol | 1978 |
Effects of antihypertensive drugs on dialysis-resistant hypertension, plasma renin and dopamine betahydroxylase activities, metabolic risk factors and calcium phosphate homeostasis: comparison of metoprolol, alphamethyldopa and clonidine in a cross-over t
Topics: Clonidine; Dopamine beta-Hydroxylase; Humans; Hypertension, Renal; Kidney Failure, Chronic; Methyldopa; Metoprolol; Propanolamines; Renal Dialysis; Renin; Risk | 1979 |
Effect of beta-blockers on psychomotor performance in normal volunteers.
Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Anxiety; Arousal; Atenolol; Diazepam; Drug Interactions; Electroencephalography; Emotions; Evoked Potentials; False Positive Reactions; Female; Health Planning; Humans; Kinetics; Male; Methyldopa; Metoprolol; Propranolol; Psychometrics; Psychomotor Performance; Reaction Time; Reference Values; Reserpine; Time Factors; Visual Acuity | 1985 |
Antihypertensive drugs that alter adrenergic function.
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Catecholamines; Central Nervous System; Clonidine; Guanethidine; Humans; Methyldopa; Metoprolol; Nadolol; Prazosin; Propanolamines; Propranolol; Receptors, Adrenergic; Reserpine; Sympathetic Nervous System | 1980 |
Clinical trials of adrenergic antagonists in pregnancy hypertension.
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Apgar Score; Birth Weight; Female; Fetal Growth Retardation; Humans; Hydralazine; Hypertension; Infant, Newborn; Methyldopa; Metoprolol; Oxprenolol; Pregnancy; Pregnancy Complications, Cardiovascular; Respiratory Distress Syndrome, Newborn | 1984 |
[Effects of long-term treatment with various antihypertensive drugs on the cardiac mass and on the hemodynamics of patients with essential arterial hypertension].
Topics: Adult; Cardiac Output; Cardiomegaly; Clonidine; Echocardiography; Heart; Humans; Hypertension; Methyldopa; Metoprolol; Middle Aged | 1983 |
Regression of structural cardiovascular changes by antihypertensive therapy in spontaneously hypertensive rats.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Cardiomegaly; Cardiovascular System; Circadian Rhythm; Felodipine; Heart Rate; Hypertension; Methyldopa; Metoprolol; Nifedipine; Rats; Rats, Inbred SHR; Time Factors | 1984 |
A comparative study of metoprolol and methyldopa in the treatment of hypertension.
Topics: Adult; Aged; Blood Pressure; Female; Heart Rate; Humans; Hypertension; Male; Methyldopa; Metoprolol; Middle Aged | 1983 |
Long-term comparison of metoprolol and methyldopa in the treatment of hypertension.
Topics: Adult; Aged; Female; Humans; Hypertension; Male; Methyldopa; Metoprolol; Middle Aged; Propanolamines; Stress, Mechanical | 1980 |
The comparison of side effects of methyldopa, amlodipine, and metoprolol in pregnant women with chronic hypertension.
Topics: Adult; Amlodipine; Antihypertensive Agents; Blood Pressure; Female; Humans; Hypertension; Incidence; Methyldopa; Metoprolol; Obstetric Labor, Premature; Pregnancy; Pregnancy Complications, Cardiovascular; Prevalence; Retrospective Studies; Risk | 2020 |