Page last updated: 2024-08-23

methyldopa and isradipine

methyldopa has been researched along with isradipine in 12 studies

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's7 (58.33)18.2507
2000's3 (25.00)29.6817
2010's2 (16.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Lombardo, F; Obach, RS; Waters, NJ1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Amir, M; Bar-On, D; Cristal, N; Loidl, A1
Arulkumaran, S; Ingemarsson, I; Montan, S; Ratnam, SS; Wide-Swensson, D1
Cristal, N; Yodfat, Y1
Amir, M; Bar-On, D1
Anandakumar, C; Arulkumaran, S; Ingemarsson, I; Montan, S; Ratnam, S1
Amir, M; Bar-On, D; Cristal, N; Yodfat, Y1
Arulkumaran, S; Biswas, A; Koh, SC; Malcus, P; Ratnam, SS; SvenMontan, S; Yin, KH1

Reviews

1 review(s) available for methyldopa and isradipine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

7 trial(s) available for methyldopa and isradipine

ArticleYear
Does the combination of ACE inhibitor and calcium antagonist control hypertension and improve quality of life? The LOMIR-MCT-IL study experience.
    Blood pressure. Supplement, 1994, Volume: 1

    Topics: Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Calcium Channel Blockers; Captopril; Double-Blind Method; Drug Therapy, Combination; Humans; Hypertension; Isradipine; Male; Methyldopa; Middle Aged; Quality of Life

1994
Effect of methyldopa and isradipine on fetal heart rate pattern assessed by computerized cardiotocography in human pregnancy.
    American journal of obstetrics and gynecology, 1993, Volume: 169, Issue:6

    Topics: Adolescent; Adult; Cardiotocography; Female; Heart Rate, Fetal; Humans; Isradipine; Methyldopa; Pre-Eclampsia; Pregnancy; Prospective Studies; Signal Processing, Computer-Assisted

1993
A multicenter, double-blind, randomized, placebo-controlled study of isradipine and methyldopa as monotherapy or in combination with captopril in the treatment of hypertension. The LOMIR-MCT-IH Research Group.
    American journal of hypertension, 1993, Volume: 6, Issue:3 Pt 2

    Topics: Adult; Captopril; Double-Blind Method; Drug Therapy, Combination; Humans; Hypertension; Isradipine; Male; Methyldopa; Middle Aged; Treatment Outcome

1993
Reexamining the quality of life of hypertensive patients. A new self-structured measure.
    American journal of hypertension, 1993, Volume: 6, Issue:3 Pt 2

    Topics: Adult; Analysis of Variance; Factor Analysis, Statistical; Humans; Hypertension; Isradipine; Male; Methyldopa; Middle Aged; Quality of Life; Reproducibility of Results; Self-Assessment; Surveys and Questionnaires

1993
Randomised controlled trial of methyldopa and isradipine in preeclampsia--effects on uteroplacental and fetal hemodynamics.
    Journal of perinatal medicine, 1996, Volume: 24, Issue:2

    Topics: Antihypertensive Agents; Blood Pressure; Female; Gestational Age; Heart Rate; Heart Rate, Fetal; Humans; Isradipine; Methyldopa; Pre-Eclampsia; Pregnancy; Pregnancy Outcome; Prospective Studies; Pulsatile Flow

1996
Quality of life in normotensives compared to hypertensive men treated with isradipine or methyldopa as monotherapy or in combination with captopril: the LOMIR-MCT-IL study.
    Journal of human hypertension, 1996, Volume: 10, Issue:2

    Topics: Adult; Aged; Analysis of Variance; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Calcium Channel Blockers; Captopril; Case-Control Studies; Double-Blind Method; Drug Therapy, Combination; Humans; Hypertension; Isradipine; Male; Methyldopa; Middle Aged; Quality of Life; Treatment Outcome

1996
Preeclampsia: haemostatic status and the short-term effects of methyldopa and isradipine therapy.
    The journal of obstetrics and gynaecology research, 1998, Volume: 24, Issue:3

    Topics: Antihypertensive Agents; Female; Hemostasis; Humans; Isradipine; Methyldopa; Pre-Eclampsia; Pregnancy; Time Factors; Treatment Outcome

1998

Other Studies

4 other study(ies) available for methyldopa and isradipine

ArticleYear
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010