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methyldopa and isoproterenol

methyldopa has been researched along with isoproterenol in 39 studies

Research

Studies (39)

TimeframeStudies, this research(%)All Research%
pre-199026 (66.67)18.7374
1990's3 (7.69)18.2507
2000's2 (5.13)29.6817
2010's8 (20.51)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lombardo, F; Obach, RS; Waters, NJ1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Barber, J; Dawson, S; Kenna, JG; Paul, N; Stahl, S1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Bellman, K; Knegtel, RM; Settimo, L1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Harrewijn, P1
Day, MD; Roach, AG1
Barnard, EA; Bhargava, AK; Hudecki, MS1
Fontan, M; Gallo, A; Gómez Llambi, H; Kuraja, I; Massadi, A; Taquini, CM1
Daya, S; Welman, AD1
Gray, RM; Harrison, WH; Solomon, LM1
Heise, A; Kroneberg, G1
Muscholl, E; Rahn, KH1
Dzoljić, M1
Klaniecki, T; Ratkin, G; Sapira, JD1
Boyd, AE; Feldman, JM; Lebovitz, HE1
Prichard, BN1
Bliss, EL; Eyzaguirre, C; Hess, A; Zapata, P1
Boudier, HA; Cools, AR; Geilen, W; Van Rossum, JM1
Saito, H; Shudo, I1
Antikainen, PJ; Witikainen, U1
Crespin, SR; Jarett, L; Smith, RM1
Cranston, WI1
Wade, OL1
Bencosme, SA; Berger, JM1
Murakami, H; Yamafuji, K1
Luczak, J; Sidor, H1
Lamont, NM; Posel, K1
Graubner, W; Wolf, M1
Dunlap, WP; Harston, CT; Hennig, CW; Macphee, AA1
Abassi, ZA; Cuda, G; Golomb, E; Keiser, HR; Panchal, VR; Stylianou, M; Trachewsky, D1
ROSS, SB1
HALJASMAA, O; ROSS, SB1
Casoni, D; Sârbu, C; Sima Tuhuţiu, IA1
Rajendiran, N; Saravanan, J; Thulasidhasan, J1

Reviews

4 review(s) available for methyldopa and isoproterenol

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Advances in medicine.
    The Practitioner, 1968, Volume: 201, Issue:204

    Topics: Acute Kidney Injury; Asthma; Blindness; Catecholamines; Contraceptives, Oral; Coronary Disease; Guanethidine; Humans; Hypertension, Malignant; Intensive Care Units; Isoproterenol; Kidney Failure, Chronic; Methyldopa; Myocardial Infarction; Obesity; Propranolol; Prostheses and Implants; Renal Dialysis; Respiratory Therapy; Starvation; Therapeutics; Thrombosis

1968
Pattern of drug-induced disease in the community. An unsolved enigma.
    British medical bulletin, 1970, Volume: 26, Issue:3

    Topics: Age Factors; Analgesics; Contraceptives, Oral; Digitalis Glycosides; Diuretics; Drug Hypersensitivity; Drug-Related Side Effects and Adverse Reactions; Humans; Isoproterenol; Methyldopa; Monoamine Oxidase Inhibitors; Registries; Sex Factors; Thromboembolism

1970
Specific granules in mammalian and non-mammalian vertebrate cardiocytes.
    Methods and achievements in experimental pathology, 1971, Volume: 5

    Topics: Animals; Atropine; Bethanechol Compounds; Catecholamines; Cats; Cattle; Cytoplasmic Granules; Dihydroxyphenylalanine; Fishes; Heart Atria; Heart Ventricles; Hemicholinium 3; Histocytochemistry; Humans; Isoproterenol; Lysosomes; Methyldopa; Microscopy, Electron; Myocardium; Nialamide; Norepinephrine; Propranolol; Rabbits; Rats; Reserpine; Sympatholytics; Sympathomimetics

1971

Other Studies

35 other study(ies) available for methyldopa and isoproterenol

ArticleYear
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
In vitro inhibition of the bile salt export pump correlates with risk of cholestatic drug-induced liver injury in humans.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Cholestasis; Drug-Related Side Effects and Adverse Reactions; Humans; Insecta; Rats; Risk Factors

2012
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
    Pharmaceutical research, 2014, Volume: 31, Issue:4

    Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation

2014
Role of monoamine metabolism in wing dimorphism of the aphid Myzus persicae.
    Comparative biochemistry and physiology. C: Comparative pharmacology, 1976, Volume: 55, Issue:2

    Topics: Animals; Aphids; Autonomic Agents; Dopamine; Fenclonine; Isoproterenol; Levodopa; Methyldopa; Norepinephrine; Physostigmine; Reserpine; Tryptamines; Wings, Animal

1976
Cardiovascular effects of dopamine after central administration into conscious cats.
    British journal of pharmacology, 1976, Volume: 58, Issue:4

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Blood Pressure; Cats; Cisterna Magna; Dopamine; Dopamine beta-Hydroxylase; Female; Ganglionic Blockers; Heart Rate; Hemodynamics; Injections; Isoproterenol; Male; Methyldopa; Receptors, Dopamine

1976
Effects of serotonin antagonists on the development of inherited muscular dystrophy in the chicken.
    Experimental neurology, 1977, Volume: 55, Issue:3 PT. 1

    Topics: Age Factors; Alkaline Phosphatase; Animals; Aspartate Aminotransferases; Body Weight; Chickens; Creatine Kinase; Cyproheptadine; Female; Isoproterenol; L-Lactate Dehydrogenase; Male; Methyldopa; Methysergide; Muscular Dystrophy, Animal; Posture; Serotonin; Serotonin Antagonists

1977
[Effect of alpha methyldopa on heart in renovascular hypertension].
    Medicina, 1990, Volume: 50, Issue:2

    Topics: Animals; Blood Pressure; Cardiomegaly; Heart Rate; Hypertension, Renovascular; Isoproterenol; Male; Methyldopa; Myocardial Contraction; Organ Size; Rats; Rats, Inbred Strains

1990
Pineal gland as a model to elucidate the primary mode of action of alpha-methyldopa: alpha-methyldopa induces an increase in the synthesis of N-acetylserotonin and melatonin levels by the rat pineal gland.
    Journal of neuroscience research, 1990, Volume: 26, Issue:1

    Topics: Animals; Isoproterenol; Male; Melatonin; Methyldopa; Organ Culture Techniques; Pineal Gland; Rats; Rats, Inbred Strains; Serotonin

1990
Incorporation of L-dopa, L-alpha-methyldopa and DL-isoproterenol into guinea pig hair.
    Acta dermato-venereologica, 1974, Volume: 54, Issue:4

    Topics: Animals; Carbon Radioisotopes; Dihydroxyphenylalanine; Guinea Pigs; Hair; Isoproterenol; Melanins; Melanocytes; Methyldopa; Skin; Time Factors; Tritium

1974
Central nervous alpha-adrenergic receptors and the mode of action of alpha-methyldopa.
    Naunyn-Schmiedeberg's archives of pharmacology, 1973, Volume: 279, Issue:3

    Topics: Adrenergic alpha-Antagonists; Angiotensin II; Animals; Aorta; Blood Pressure; Catecholamines; Cats; Cerebral Ventricles; Cocaine; Dopamine; Dose-Response Relationship, Drug; Drug Interactions; Hypotension; Isoproterenol; Methyldopa; Norepinephrine; Perfusion; Phentolamine; Propranolol; Rats; Receptors, Adrenergic; Reserpine; Tyramine; Yohimbine

1973
[On the importance of the formation of metabolites for the blood pressure-lowering effect of alpha-methyldopa].
    Naunyn-Schmiedebergs Archiv fur experimentelle Pathologie und Pharmakologie, 1967, Volume: 257, Issue:1

    Topics: Blood Pressure; Catecholamines; Hypertension; Isoproterenol; Methyldopa; Propranolol

1967
Peristaltic reflex and hypotensive drugs.
    Archives internationales de pharmacodynamie et de therapie, 1965, Volume: 156, Issue:2

    Topics: Acetylcholine; Angiotensin II; Animals; Bis-Trimethylammonium Compounds; Gastrointestinal Motility; Guanethidine; Guinea Pigs; Ileum; In Vitro Techniques; Isoproterenol; Methyldopa; Nicotine; Phentolamine; Reflex; Reserpine; Serotonin

1965
"Non-pheochromocytoma".
    JAMA, 1970, Jun-29, Volume: 212, Issue:13

    Topics: Adrenal Gland Neoplasms; Adult; Arteriovenous Fistula; Asthma; Celiac Disease; Child, Preschool; Diagnosis, Differential; Female; Humans; Hypertension; Isoproterenol; Kidney Neoplasms; Male; Methyldopa; Middle Aged; Pheochromocytoma; Renal Artery Obstruction; Vanilmandelic Acid; Wilms Tumor

1970
Structural determinants of catecholamine action on in vitro insulin release.
    The Journal of pharmacology and experimental therapeutics, 1971, Volume: 176, Issue:3

    Topics: Animals; Butyrates; Catecholamines; Cricetinae; Cyclic AMP; Dihydroxyphenylalanine; Dopamine; Epinephrine; Glucose; In Vitro Techniques; Insulin; Insulin Secretion; Isoproterenol; Methyldopa; Norepinephrine; Pancreas; Phenethylamines; Phentolamine; Phenylacetates; Phenylalanine; Phenylephrine; Structure-Activity Relationship; Tyramine; Tyrosine

1971
The treatment of hypertension by beta adrenergic blocking drugs.
    Angiologica, 1966, Volume: 3, Issue:5

    Topics: Antihypertensive Agents; Ergot Alkaloids; Ethanolamines; Guanethidine; Humans; Hypertension; Isoproterenol; Methyldopa; Norepinephrine; Phenoxybenzamine; Propranolol; Reserpine

1966
Chemical, electron microscopic and physiological observations on the role of catecholamines in the carotid body.
    Brain research, 1969, Volume: 14, Issue:2

    Topics: Adrenalectomy; Animals; Carotid Body; Catecholamines; Cats; Chemoreceptor Cells; Dihydroxyphenylalanine; Dopamine; Epinephrine; In Vitro Techniques; Injections, Intravenous; Isoproterenol; Methyldopa; Microscopy, Electron; Norepinephrine; Peripheral Nerves; Pressoreceptors; Reserpine; Sympathectomy; Tyramine

1969
Pharmacological analysis of dopamine-induced inhibition and excitation of neurones of the snail Helix aspersa.
    Archives internationales de pharmacodynamie et de therapie, 1974, Volume: 209, Issue:2

    Topics: Animals; Apomorphine; Butyrophenones; Dopamine; Dopamine Antagonists; Droperidol; Epinephrine; Ergot Alkaloids; Haloperidol; In Vitro Techniques; Isoproterenol; Methyldopa; Neurons; Norepinephrine; Phenylephrine; Snails; Time Factors

1974
[Micro-fluorescence method for the determination of isoproterenol, protokylol and alpha-methyl dopa].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1972, Volume: 68, Issue:4

    Topics: Animals; Brain Chemistry; Dioxoles; Fluorescence; Intestines; Isoproterenol; Kidney; Liver; Lung; Methyldopa; Microchemistry; Muscles; Myocardium; Phenethylamines; Rats; Spectrum Analysis; Spleen; Sympathomimetics

1972
A comparative study on the ionization of catechol amines in aqueous solutions.
    Acta chemica Scandinavica, 1973, Volume: 27, Issue:6

    Topics: Boric Acids; Catecholamines; Dihydroxyphenylalanine; Dopamine; Isoproterenol; Methyldopa; Potassium Chloride; Potentiometry

1973
A problem in pulmonary hypertension. 1. The clinical course. A clinicopathologic conference from the Division of Pulmonary Diseases, Hahnemann Medical College and Hospital, Philadelphia.
    Chest, 1974, Volume: 65, Issue:1

    Topics: Acetylcholine; Adult; Cardiac Catheterization; Diagnosis, Differential; Edrophonium; Electrocardiography; Hemodynamics; Humans; Hypertension, Pulmonary; Isoproterenol; Lung; Male; Methyldopa; Oxygen; Pulmonary Artery; Pulmonary Embolism; Radiography; Radionuclide Imaging; Respiratory Function Tests; Vascular Resistance

1974
Epinephrine binding to rat adipocytes and their subcellular fractions.
    Endocrinology, 1974, Volume: 94, Issue:3

    Topics: Adipose Tissue; Animals; Binding Sites; Cell Membrane; Dihydroxyphenylalanine; Epinephrine; Isoproterenol; Liver; Methyldopa; Microsomes; Mitochondria; Mitochondria, Liver; Phentolamine; Propranolol; Rats; Tritium; Tyrosine

1974
Mode of action of some catecholamines and sugar oximes on deoxyribonucleic acid.
    Enzymologia, 1970, Jun-30, Volume: 38, Issue:6

    Topics: Acetates; Arabinose; Chemical Phenomena; Chemistry; Cobalt; Copper; DNA; Galactose; Glucose; Isoproterenol; Ketoglutaric Acids; Kinetics; Methyldopa; Models, Chemical; Models, Structural; Nucleotides; Oximes; Polynucleotides; Pyrimidines; Pyruvates; Spectrophotometry; Ultraviolet Rays; Viscosity; Zinc

1970
[A case of carcinoid treated conservatively].
    Polski tygodnik lekarski (Warsaw, Poland : 1960), 1969, Jan-27, Volume: 24, Issue:4

    Topics: Adult; Carcinoid Tumor; Ergolines; Female; Humans; Isoproterenol; Liver Neoplasms; Methyldopa; Phenylacetates

1969
The coronary attack: concepts on its etiology and hemodynamic management.
    American heart journal, 1969, Volume: 78, Issue:4

    Topics: Aged; Arrhythmias, Cardiac; Aspartate Aminotransferases; Biophysical Phenomena; Biophysics; Blood Flow Velocity; Blood Pressure; Cardiac Output; Coronary Disease; Digoxin; Electrocardiography; Heart; Heart Failure; Humans; Hydrocortisone; Hypotension; Isoproterenol; Lidocaine; Male; Methyldopa; Middle Aged; Models, Biological; Propranolol; Stress, Psychological; Veins

1969
[Critical considerations on the method of action of 2-(2,6-dichlorophenylamino)-2-imidazoline-hydrochloride].
    Arzneimittel-Forschung, 1966, Volume: 16, Issue:8

    Topics: Animals; Antihypertensive Agents; Bretylium Compounds; Cats; Guanethidine; Humans; Imidazoles; Isoproterenol; Methyldopa; Mice; Parasympathetic Nervous System; Phentolamine; Rabbits; Rats; Reserpine; Sympathetic Nervous System

1966
Tonic immobility and the alpha-adrenergic system in chickens.
    Physiology & behavior, 1980, Volume: 24, Issue:1

    Topics: Animals; Chickens; Clonidine; Epinephrine; Isoproterenol; Methoxamine; Methyldopa; Motor Activity; Norepinephrine; Phenylephrine; Receptors, Adrenergic; Receptors, Adrenergic, alpha

1980
Angiotensin II maintains, but does not mediate, isoproterenol-induced cardiac hypertrophy in rats.
    The American journal of physiology, 1994, Volume: 267, Issue:4 Pt 2

    Topics: Actins; Angiotensin II; Animals; Base Sequence; Biphenyl Compounds; Blood Pressure; Captopril; Cardiomegaly; DNA; DNA Primers; Dose-Response Relationship, Drug; Gene Expression; Genes, fos; Heart; Hydralazine; Hydroxyproline; Imidazoles; Isoproterenol; Labetalol; Losartan; Male; Methyldopa; Molecular Sequence Data; Myocardium; Myosins; Polymerase Chain Reaction; Rats; Rats, Sprague-Dawley; RNA; RNA, Messenger; Tetrazoles; Transcription, Genetic

1994
EFFECTS OF VARIOUS COMPOUNDS ON ADRENERGIC MECHANISMS RECORDED BY CHANGES IN HEART RATES OF ANESTHETISED MICE.
    Acta pharmacologica et toxicologica, 1963, Volume: 20

    Topics: Adrenergic Agents; Antihypertensive Agents; Epinephrine; Heart; Heart Rate; Isoproterenol; Methyldopa; Mice; Monoamine Oxidase Inhibitors; Norepinephrine; Pharmacology; Research; Sympatholytics; Tyramine

1963
CATECHOL-O-METHYL TRANSFERASE INHIBITORS. IN VIVO INHIBITION IN MICE.
    Acta pharmacologica et toxicologica, 1964, Volume: 21

    Topics: Aldehydes; Benzoates; Brain; Catechol O-Methyltransferase; Catecholamines; Cinnamates; Enzyme Inhibitors; Flavonoids; Gallic Acid; Hydrolyzable Tannins; Isoproterenol; Methyldopa; Pharmacology; Phenols; Pyrogallol; Quinolines; Research; Sympatholytics; Sympathomimetics; Tachycardia; Tannins; Transferases

1964
High sensitive and selective HPTLC method assisted by digital image processing for simultaneous determination of catecholamines and related drugs.
    Talanta, 2013, Sep-30, Volume: 114

    Topics: Biphenyl Compounds; Catecholamines; Chromatography, Thin Layer; Image Processing, Computer-Assisted; Isoproterenol; Methyldopa; Picrates; Reproducibility of Results

2013
Inclusion complexation of isoprenaline and methyl dopa with α- and β-cyclodextrin nanocavities: spectral and theoretical study.
    Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2014, 03-25, Volume: 122

    Topics: alpha-Cyclodextrins; Antihypertensive Agents; beta-Cyclodextrins; Bronchodilator Agents; Calorimetry, Differential Scanning; Isoproterenol; Magnetic Resonance Spectroscopy; Methyldopa; Models, Molecular; Nanostructures; Solubility; Spectroscopy, Fourier Transform Infrared; X-Ray Diffraction

2014