Page last updated: 2024-08-23

methyldopa and hydrazine

methyldopa has been researched along with hydrazine in 117 studies

Research

Studies (117)

Timeframe	Studies, this research(%)	All Research%
pre-1990	114 (97.44)	18.7374
1990's	0 (0.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	3 (2.56)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ	1
Glen, RC; Lowe, R; Mitchell, JB	1
Ekins, S; Williams, AJ; Xu, JJ	1
Bertrand, JC; Lareng, L	1
Gierlichs, HW; Hawlina, A; Planz, G; Planz, R; Rahn, KH; Stephany, W	1
Doyle, AE; Jarrott, B; Louis, WJ; McNeil, JJ; Vajda, FJ	1
Combépine, C; Geissbühler, F; Hovaguimian, T; Raffin, Y; Streiff, U	1
Dybing, E; McMurtry, RJ; Mitchell, JR; Nelson, SD; Thorgeirsson, SS	1
Weinreich, D	1
Goodale, DB; Moore, KE	1
Mosnaim, AD; Silkaitis, RP	1
Geissbühler, F; Widmer, J	1
Ludden, CT; Scriabine, A; Stone, CA; Watkins, CJ; Wurtman, RJ	1
Nevsímal, O; Roth, B; Vymazal, J	1
Hey, JA; Ito, T; Koss, MC	1
Chase, TN; Ng, L; Passananti, GT; Vesell, ES	1
Chase, TN; Fermaglich, J	1
Korf, J; Postema, F; Venema, K	1
Lotti, VJ; Stone, CA; Torchiana, ML	1
Atkins, FL; Beaven, MA; Keiser, HR	1
Fournier, A; Lagrue, G; Schmitt, H	1
Munro, HN; Roel, LE; Weiss, BF; Wurtman, RJ	1
Andén, NE; Engel, J; Rubenson, A	1
Dunkley, B; Friedman, E; Gershion, S; Sanghvi, I	1
Senault, B	1
Modigh, K	1
Seiden, LS; Uretsky, NJ	1
Henning, M	3
Brodie, HK; Bunney, WE; Goodwin, FK; Murphy, DL	1
Robson, RD	1
Gershon, S; Wallach, MB	2
Delesie, R; Fahn, S; Prasad, AL	1
Adlercreutz, H; Castrén, O; Härkönen, M; Raij, K; Saarikoski, S	1
Shore, PA	1
Gal, EM; Marshall, FD; Morgan, M	1
Norberg, KA	1
Renyi, AL; Ross, SB	1
Robinson, D; Sharman, DF	1
Batson, HM; Birchall, R; Weber, GF	1
Clarke, DE; Leach, GD	1
Cottier, P	1
McGill, JS; Pruss, TP	1
Barrett, AM	1
Hamilton, AE; Horita, A	1
Porter, CC; Torchiana, ML	1
Hitzenberger, G	1
Henning, M; Rubenson, A	1
Dineen, JK; Love, RJ; Rothwell, TL	1
Baldessarini, RJ	1
Eichelman, B; Ng, KY; Thoa, NB	1
Munro, HN; Ordonez, LA; Weiss, BF; Wurtman, RJ	1
Henning, M; Rubenson, A; Trolin, G	1
Bessler, H; Djaldetti, M; Lewinski, U; Mandel, EM	1
Hamilton, AE; Horita, A; Nair, X	1
Kellogg, C; Lundborg, P	1
Hare, TA; Mahoney, K; Vogel, WH	1
Chase, TN; Colburn, RW; Kopin, IJ; Ng, LK	1
Bell, MA; Cotzias, GC; Düby, SE; Fehling, C; Papavasiliou, PS; Steck, AJ	1
Galanter, M; Green, R; Kaplan, J; Vaughan, T; Wyatt, RJ	1
Allen, JG; Calne, DB; Davies, CA; Reid, JL; Vakil, SD	1
Chase, TN; Ng, LK; Watanabe, AM	1
Mones, RJ	1
Andén, NE; Engel, J	1
Anagnoste, B; Battista, AF; Fuxe, K; Goldstein, M; Ohmoto, T	1
Bianchine, JR; Hsu, TH; Messiha, FS	1
Calne, DB; George, CF; Reid, JL; Vakil, SD	1
Mars, H	1
Calne, DB; Reid, JL	1
Froment, A; Milon, H	1
Bartholini, G; Constantinidis, J; de Ajuriaguerra, J; Eisenring, JJ; Geissbühler, F; Tissot, R; Yanniotis, G	1
Andén, NE; Henning, M	1
Cohen, Y; Jacquot, C; Rapin, J; Wepierre, J	1
Fahn, S	1
Cotzias, GC; Ginos, JZ; Nicholson, AR; Papavasiliou, PS; Tang, L	1
Calne, DB; Gawler, J; Hilson, A; Pallis, CA; Petrie, A; Rao, S; Reid, JL; Thomas, PK; Vakil, SD	1
Sundermann, A	1
Calne, DB; Petrie, A; Rao, S; Reid, JL; Vakil, SD	1
Lampart, C; Rose, C; Schwartz, JC	2
Jonsson, G; Sachs, C	1
Day, MD; Roach, AG; Whiting, RL	1
Bravo, EL; Dustan, HP; Tarazi, RC	1
Chase, TN; Watanabe, AM	1
Barrera, ER; Bennett, S; Mars, H	1
Colburn, RW; Kopin, IJ; Ng, LK	1
Hagino, K	1
Constantinidis, J; Eisenring, JJ; Geissbühler, F; Krassoievitch, M; Tissot, R; Yanniotis, G	1
Krall, J; Mars, H	1
Landsberg, L	1
Snyder, SH; Taylor, KM	1
Barrett, RE; Duvoisin, RC; Mendoza, MR; Schear, MJ; Yahr, MD	1
Cotzias, GC	1
Aramaki, Y; Kikuchi, K; Nagaoka, A	1
Chase, TN	1
Colburn, RW; Kopin, IJ; Ng, KY	1
Shepherd, DM; Woodcock, BG	1
Bruinvels, J; Sourkes, TL	1
Dalla Volta, S	1
Bartholini, G; Pletscher, A; Tissot, R	1
Erickson, RW; Green, H	1
Christensen, HD; Gherezghiher, T; Koss, MC	2
BYER, SS; PORTER, CC; TITUS, DC; TOTARO, JA; WATSON, LS	1
DAVIS, RA; DRAIN, DJ; HORLINGTON, M; LAZARE, R; URBANSKA, A	1
KAHLSON, G; ROSENGREN, E; THUNBERG, R	1
KUNZ, E	1
MONTANDON, A	1
BURKARD, WP; GEY, KF; PLETSCHER, A	1
BOLLINGER, FW; CHEMERDA, JM; SLETZINGER, M	1
DUHAULT, J; FENARD, S; GONNARD, P	1
LEVINE, RJ; SATO, TL; SJOERDSMA, A	1
HIGH, DP; SHEPHERD, DM; WOODCOCK, BG	1
PLETSCHER, A; PRADAM, DA; STEINER, FA	1

Reviews

2 review(s) available for methyldopa and hydrazine

Article	Year
Metabolic activation: biochemical basis for many drug-induced liver injuries. Progress in liver diseases, 1976, Volume: 5 Topics: Acetaminophen; Animals; Binding Sites; Carcinogens; Chemical and Drug Induced Liver Injury; Drug Hypersensitivity; Drug-Related Side Effects and Adverse Reactions; Furosemide; Humans; Hydrazines; Isoniazid; Liver; Methyldopa; Necrosis; Pharmaceutical Preparations; Phenacetin; Thiophenes	1976
Studies on the mode of action of alpha-methyldopa. Acta physiologica Scandinavica. Supplementum, 1969, Volume: 322 Topics: Aminocaproates; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Blood Pressure; Brain Chemistry; Catecholamines; Hydrazines; Hypertension; Injections; Methyldopa; Methyltyrosines; Muscles; Myocardium; Neurons; Propionates; Rats; Reserpine; Sympathetic Nervous System; Synaptic Transmission; Time Factors	1969

Article

Year

Metabolic activation: biochemical basis for many drug-induced liver injuries.

Progress in liver diseases, 1976, Volume: 5

Topics: Acetaminophen; Animals; Binding Sites; Carcinogens; Chemical and Drug Induced Liver Injury; Drug Hypersensitivity; Drug-Related Side Effects and Adverse Reactions; Furosemide; Humans; Hydrazines; Isoniazid; Liver; Methyldopa; Necrosis; Pharmaceutical Preparations; Phenacetin; Thiophenes

1976

Studies on the mode of action of alpha-methyldopa.

Acta physiologica Scandinavica. Supplementum, 1969, Volume: 322

Topics: Aminocaproates; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Blood Pressure; Brain Chemistry; Catecholamines; Hydrazines; Hypertension; Injections; Methyldopa; Methyltyrosines; Muscles; Myocardium; Neurons; Propionates; Rats; Reserpine; Sympathetic Nervous System; Synaptic Transmission; Time Factors

1969

Trials

12 trial(s) available for methyldopa and hydrazine

Article	Year
Influence of the decarboxylase inhibitor benserazide on the antihypertensive effect and metabolism of alpha-methyldopa in patients with essential hypertension. European journal of clinical pharmacology, 1977, Dec-02, Volume: 12, Issue:4 Topics: Adult; Benserazide; Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Drug Interactions; Female; Humans; Hydrazines; Hypertension; Male; Methyldopa; Middle Aged; Placebos	1977
The combined use of L-alpha-methyldopa hydrazine and methyldopa in the treatment of hypertension. Clinical and experimental pharmacology & physiology. Supplement, 1978, Volume: 4 Topics: Adult; Aged; Clinical Trials as Topic; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydrazines; Hypertension; Levodopa; Male; Methyldopa; Middle Aged; Placebos; Time Factors	1978
Methyldopa or methyldopahydrazine as levodopa synergists. Lancet (London, England), 1973, Jun-02, Volume: 1, Issue:7814 Topics: Carbidopa; Dihydroxyphenylalanine; Drug Synergism; Humans; Hydrazines; Methyldopa; Parkinson Disease	1973
Regular induction of hypomania by L-dopa in "bipolar" manic-depressive patients. Nature, 1971, Jan-08, Volume: 229, Issue:5280 Topics: Antidepressive Agents; Bipolar Disorder; Catecholamines; Clinical Trials as Topic; Dihydroxyphenylalanine; Dopamine; Euphoria; Female; Humans; Hydrazines; Male; Methyldopa; Methyltyrosines; Middle Aged; Phenylacetates; Placebos; Psychomotor Disorders; Sleep, REM; Stereoisomerism; Visual Cortex	1971
Levodopa in Parkinsonism: potentiation of central effects with a peripheral inhibitor. The New England journal of medicine, 1972, Jan-06, Volume: 286, Issue:1 Topics: Administration, Oral; Adult; Biotransformation; Brain; Carbon Monoxide Poisoning; Cerebral Palsy; Child; Clinical Trials as Topic; Dihydroxyphenylalanine; Dopamine; Drug Synergism; Female; Humans; Hydrazines; Male; Methyldopa; Neurologic Examination; Neuromuscular Diseases; Parkinson Disease; Phenylacetates; Pyridoxine; Time Factors	1972
Behavioral changes of chronic schizophrenic patients given L-5-hydroxytryptophan. Science (New York, N.Y.), 1972, Sep-22, Volume: 177, Issue:4054 Topics: 5-Hydroxytryptophan; Administration, Oral; Adult; Brain; Carboxy-Lyases; Clinical Trials as Topic; Humans; Hydrazines; Hydroxyindoleacetic Acid; Male; Methyldopa; Paranoid Disorders; Placebos; Schizophrenia; Serotonin	1972
Plasma concentration of levodopa in Parkinsonism before and after inhibition of peripheral decarboxylase. Journal of the neurological sciences, 1972, Volume: 17, Issue:1 Topics: Carboxy-Lyases; Clinical Trials as Topic; Dihydroxyphenylalanine; Humans; Hydrazines; Male; Methyldopa; Movement Disorders; Parkinson Disease	1972
Parkinson's disease. Modification by 5-hydroxytryptophan. Neurology, 1972, Volume: 22, Issue:5 Topics: 5-Hydroxytryptophan; Adult; Aged; Brain; Carboxy-Lyases; Clinical Trials as Topic; Drug Synergism; Evaluation Studies as Topic; Extrapyramidal Tracts; Female; Humans; Hydrazines; Hydroxyindoleacetic Acid; Male; Methyldopa; Middle Aged; Parkinson Disease; Phenylacetates; Placebos; Serotonin	1972
Evaluation of alpha methyl dopa and alpha methyl dopa hydrazine with L-dopa therapy. New York state journal of medicine, 1974, Volume: 74, Issue:1 Topics: Adult; Aged; Carbidopa; Clinical Trials as Topic; Dihydroxyphenylalanine; Drug Evaluation; Drug Therapy, Combination; Humans; Hydrazines; Methyldopa; Middle Aged; Parkinson Disease	1974
Idiopathic Parkinsonism treated with an extracerebral decarboxylase inhibitor in combination with levodopa. British medical journal, 1971, Sep-25, Volume: 3, Issue:5777 Topics: Adult; Aged; Aromatic Amino Acid Decarboxylase Inhibitors; Clinical Trials as Topic; Dihydroxyphenylalanine; Drug Synergism; Female; Humans; Hydrazines; Male; Methyldopa; Middle Aged; Nausea; Parkinson Disease; Vomiting	1971
Action of L- -methyldopa-hydrazine on the blood pressure of patients receiving levodopa. British journal of pharmacology, 1972, Volume: 44, Issue:1 Topics: Adult; Aged; Blood Pressure; Dihydroxyphenylalanine; Dopamine; Female; Humans; Hydrazines; Hypotension; Male; Methyldopa; Middle Aged; Parkinson Disease; Pulse	1972
Methyldopahydrazine as an adjunct to L-dopa therapy in parkinsonism. Neurology, 1972, Volume: 22, Issue:4 Topics: Adolescent; Adult; Aged; Blood Pressure; Brain; Child; Dihydroxyphenylalanine; Dopamine; Evaluation Studies as Topic; Female; Gastrointestinal Diseases; Heart; Humans; Hydrazines; Hydroxyindoleacetic Acid; Male; Methyldopa; Middle Aged; Motor Skills; Parkinson Disease; Phenylacetates; Serotonin	1972

Other Studies

103 other study(ies) available for methyldopa and hydrazine

Article	Year
Developing structure-activity relationships for the prediction of hepatotoxicity. Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes	2010
Predicting phospholipidosis using machine learning. Molecular pharmaceutics, 2010, Oct-04, Volume: 7, Issue:5 Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine	2010
A predictive ligand-based Bayesian model for human drug-induced liver injury. Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12 Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands	2010
[Drug interference and the role of anesthesia in such interference]. Annales de l'anesthesiologie francaise, 1975, Volume: 16 Spec No 1 Topics: Adrenal Cortex Hormones; Adrenergic alpha-Antagonists; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Anesthesia, Obstetrical; Antidepressive Agents; Antihypertensive Agents; Barbiturates; Diuretics; Drug Antagonism; Drug Synergism; Estrogens; Female; Histamine H1 Antagonists; Humans; Hydrazines; Insulin; Methyldopa; Monoamine Oxidase Inhibitors; Oxytocics; Phthalazines; Pregnancy; Pregnancy Complications; Progestins; Reserpine; Tranquilizing Agents	1975
[Endogenous 3-O-methyldopa in man: normal level and effect of an inhibitor of aromatic amino-acid decarboxylase (Benserazid) (author's transl)]. Journal of clinical chemistry and clinical biochemistry. Zeitschrift fur klinische Chemie und klinische Biochemie, 1978, Volume: 16, Issue:6 Topics: Aromatic Amino Acid Decarboxylase Inhibitors; Benserazide; Humans; Hydrazines; Methyldopa; Spectrometry, Fluorescence	1978
The characterization of histidine decarboxylase and its distribution in nerves, ganglia and in single neuronal cell bodies from the CNS of Aplysia californica. Journal of neurochemistry, 1977, Volume: 28, Issue:2 Topics: Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Brocresine; Caffeic Acids; Carboxy-Lyases; Dopa Decarboxylase; Ganglia; Histamine; Histidine; Histidine Decarboxylase; Hydrazines; Methyldopa; Mollusca; Nervous System; Neurons; Organ Culture Techniques; Organ Specificity; Salicylates	1977
A comparison of the effects of decarboxylase inhibitors on L-dopa-induced circling behavior and the conversion of dopa to dopamine in the brain. Life sciences, 1976, Sep-01, Volume: 19, Issue:5 Topics: Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Behavior, Animal; Benserazide; Brain; Brocresine; Carbidopa; Dopamine; Hydrazines; Levodopa; Male; Methyldopa; Rats; Time Factors	1976
Pathways linking L-phenylalanine and 2-phenylethylamine with p-tyramine in rabbit brain. Brain research, 1976, Sep-10, Volume: 114, Issue:1 Topics: Animals; Brain; Hydrazines; Male; Methyldopa; Pargyline; Phenethylamines; Phenylalanine; Rabbits; Tyramine	1976
[Urinary excretion of 3,4-dihydroxyphenyl-alanine, 3-O-methyldopa, dopamine and homovanillic acid in man. Effects of an inhibitor of decarboxylase of aromatic amino acids (Benserazide) (author's transl)]. Journal of clinical chemistry and clinical biochemistry. Zeitschrift fur klinische Chemie und klinische Biochemie, 1976, Volume: 14, Issue:11 Topics: Adult; Benserazide; Dihydroxyphenylalanine; Dopamine; Female; Homovanillic Acid; Humans; Hydrazines; Male; Methyldopa; Phenylacetates; Time Factors	1976
Enhancement of the anti-hypertensive effect of methyldopa and other anti-hypertensive drugs by carbidopa in spontaneously hypertensive rats. Clinical science and molecular medicine. Supplement, 1976, Volume: 3 Topics: Animals; Antihypertensive Agents; Carbidopa; Catecholamines; Dose-Response Relationship, Drug; Drug Synergism; Hydrazines; Hypertension; Male; Methyldopa; Myocardium; Rats	1976
[Experiences in the treatment of Parkinsonism using a combination of L-dopa and alpha-methyldopa-hydrazine]. Ceskoslovenska neurologie a neurochirurgie, 1976, Volume: 39, Issue:2 Topics: Adult; Aged; Drug Combinations; Drug Evaluation; Drug Synergism; Humans; Hydrazines; Levodopa; Methyldopa; Middle Aged; Parkinson Disease	1976
alpha-Methyldopa produces mydriasis in the rat by stimulation of CNS alpha 2-adrenoceptors. British journal of pharmacology, 1988, Volume: 94, Issue:3 Topics: Adrenergic alpha-Antagonists; Animals; Biogenic Monoamines; Bis(4-Methyl-1-Homopiperazinylthiocarbonyl)disulfide; Central Nervous System; Enzyme Inhibitors; Hydrazines; Male; Methyldopa; Pupil; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha	1988
Inhibition of drug metabolism by levodopa in combination with a dopa-decarboxylase inhibitor. Lancet (London, England), 1971, Aug-14, Volume: 2, Issue:7720 Topics: Administration, Oral; Adult; Aged; Antipyrine; Aromatic Amino Acid Decarboxylase Inhibitors; Dihydroxyphenylalanine; Drug Synergism; Humans; Hydrazines; Methyldopa; Middle Aged; Pharmaceutical Preparations; Time	1971
Decarboxylation of exogenous L-5-hydroxytryptophan after destruction of the cerebral raphe system. Journal of neurochemistry, 1974, Volume: 23, Issue:1 Topics: 5-Hydroxytryptophan; Animals; Autoanalysis; Brain; Carboxy-Lyases; Cerebral Cortex; Histocytochemistry; Hydrazines; Hydroxyindoleacetic Acid; Male; Methyldopa; Phenylalanine; Rats; Serotonin; Staining and Labeling; Stereotaxic Techniques; Time Factors	1974
The anticonvulsant effect of carbonic anhydrase inhibitors in mice--a noradrenergic mechanism of action. European journal of pharmacology, 1973, Volume: 21, Issue:3 Topics: Acetazolamide; Amino Acids; Animals; Anticonvulsants; Carbonic Anhydrase Inhibitors; Carboxy-Lyases; Dichlorphenamide; Dihydroxyphenylalanine; Disulfiram; Dopamine beta-Hydroxylase; Dose-Response Relationship, Drug; Electroshock; Female; Hydrazines; Methazolamide; Methyldopa; Mice; Monoamine Oxidase Inhibitors; Picolinic Acids; Reserpine	1973
Dopa decarboxylase in medullary carcinoma of the thyroid. The New England journal of medicine, 1973, Sep-13, Volume: 289, Issue:11 Topics: Adrenal Gland Neoplasms; Amine Oxidase (Copper-Containing); Aromatic Amino Acid Decarboxylase Inhibitors; Carbidopa; Carcinoma; Cresols; Dihydroxyphenylalanine; Dopa Decarboxylase; Histamine; Histidine; Humans; Hydrazines; Hydroxylamines; Methyldopa; Methylhistidines; Norepinephrine; Pheochromocytoma; Serotonin; Thyroid Gland; Thyroid Neoplasms; Tryptophan; Tyrosine; Tyrosine 3-Monooxygenase	1973
[Pharmacological basis of the symptomatic treatment of arterial hypertension. II. Antihypertensive agent combinations]. La Nouvelle presse medicale, 1973, Nov-03, Volume: 2, Issue:39 Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Clonidine; Diazoxide; Diuretics; Drug Antagonism; Drug Synergism; Drug Therapy, Combination; Ganglionic Blockers; Guanethidine; Heterocyclic Compounds; Humans; Hydrazines; Hypertension; Methyldopa; Monoamine Oxidase Inhibitors; Reserpine	1973
The effect of L-DOPA on brain polysomes and protein synthesis: probable mediation by intracellular dopamine. Advances in neurology, 1974, Volume: 5 Topics: 5-Hydroxytryptophan; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Brain; Carbon Radioisotopes; Decarboxylation; Depression, Chemical; Dihydroxyphenylalanine; Dopamine; Drug Interactions; Enzyme Inhibitors; Hydrazines; Leucine; Levodopa; Lysine; Male; Methyldopa; Nerve Tissue Proteins; Norepinephrine; Polyribosomes; Rats; S-Adenosylmethionine; Time Factors	1974
Central decarboxylation and uptake of L-DOPA. Naunyn-Schmiedeberg's archives of pharmacology, 1972, Volume: 273, Issue:1 Topics: Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Capillaries; Decarboxylation; Dihydroxyphenylalanine; Dopamine; Hydrazines; Male; Methyldopa; Nerve Endings; Rats; Receptors, Adrenergic; Spinal Cord	1972
Comparison of behavioral and cardiovascular effects of L-DOPA and 5-HTP in conscious dogs. Psychopharmacologia, 1972, Volume: 26, Issue:2 Topics: Animals; Behavior, Animal; Blood Pressure; Cardiovascular System; Dihydroxyphenylalanine; Dogs; Female; Fenclonine; Haloperidol; Hydrazines; Injections, Intramuscular; Injections, Intraperitoneal; Injections, Intravenous; Male; Methyldopa; Methysergide; Serotonin	1972
[Brain amines and apomorphine-induced intraspecific aggressive behavior in the rat (author's transl)]. Psychopharmacologia, 1974, Jan-11, Volume: 34, Issue:2 Topics: 5-Hydroxytryptophan; Aggression; Animals; Apomorphine; Biogenic Amines; Brain; Brain Chemistry; Clonidine; Dihydroxyphenylalanine; Dioxoles; Disulfides; Fenclonine; Humans; Hydrazines; Hydroxybutyrates; Imidazoles; Iproniazid; Male; Methyldopa; Methyltyrosines; Phenoxybenzamine; Piperazines; Rats; Reserpine; Serotonin; Thiocarbamates; Time Factors	1974
Functional aspects of 5-hydroxytryptamine turnover in the central nervous system. Acta physiologica Scandinavica. Supplementum, 1974, Volume: 403 Topics: 5-Hydroxytryptophan; Acetamides; Animals; Antidepressive Agents; Brain; Catecholamines; Depression, Chemical; Dihydroxyphenylalanine; Fenclonine; Humans; Hydrazines; Imipramine; Male; Methyldopa; Motor Activity; Nialamide; Receptors, Drug; Reserpine; Serotonin; Stimulation, Chemical; Stress, Psychological; Tryptophan; Tyrosine	1974
Effect of alpha-methyl dopa on the reserpine-induced suppression of motor activity and the conditioned avoidance response. The Journal of pharmacology and experimental therapeutics, 1969, Volume: 168, Issue:1 Topics: Amines; Animals; Avoidance Learning; Brain Chemistry; Carboxy-Lyases; Conditioning, Psychological; Dopamine; Hydrazines; Methyldopa; Motor Activity; Norepinephrine; Pharmaceutical Vehicles; Rats; Reserpine; Synaptic Transmission	1969
Modification of the cardiovascular effects of L-dopa in anesthetized dogs by inhibitors of enzymes involved in catecholamine metabolism. Circulation research, 1971, Volume: 28, Issue:6 Topics: Angiotensin II; Animals; Blood Pressure; Bradycardia; Carboxy-Lyases; Cresols; Dihydroxyphenylalanine; Dogs; Dopamine; Female; Heart Rate; Hydrazines; Hypertension; Hypotension; Male; Methyldopa; Monoamine Oxidase Inhibitors; Norepinephrine; Tachycardia; Thiocarbamates	1971
A neuropsychopharmacological comparison of d-amphetamine, L-dopa and cocaine. Neuropharmacology, 1971, Volume: 10, Issue:6 Topics: Animals; Behavior, Animal; Cats; Cocaine; Cortical Synchronization; Dextroamphetamine; Dihydroxyphenylalanine; Electroencephalography; Female; Hair; Humans; Hydrazines; Male; Methyldopa; Paranoid Disorders; Parkinson Disease; Phenethylamines; Reticular Formation; Salivation; Sleep, REM; Stereoisomerism	1971
A reliable and simple method for simultaneous determination of DOPA and 3-O-methyldopa in plasma and brain. Analytical biochemistry, 1972, Volume: 46, Issue:2 Topics: Antiparkinson Agents; Brain Chemistry; Carbon Isotopes; Chromatography, Ion Exchange; Cold Temperature; Dihydroxyphenylalanine; Edetic Acid; Epinephrine; Ferricyanides; Humans; Hydrazines; Hydrogen-Ion Concentration; Iodine; Methods; Methyldopa; Norepinephrine; Oxidation-Reduction; Parkinson Disease; Perchlorates; Periodic Acid; Spectrometry, Fluorescence	1972
Urinary cyclic AMP excretion in toxaemia of pregnancy. Scandinavian journal of clinical and laboratory investigation, 1973, Volume: 32, Issue:3 Topics: Cyclic AMP; Cyclohexanes; Diazepam; Estriol; Female; Furosemide; Heterocyclic Compounds; Humans; Hydrazines; Hydrochlorothiazide; Isoxsuprine; Mandelic Acids; Methyldopa; Pre-Eclampsia; Pregnancy; Protoveratrines; Pyridazines; Radioimmunoassay; Reserpine	1973
The mechanism of norepinephrine depletion by reserpine, metaraminol and related agents. The role of monoamine oxidase. Pharmacological reviews, 1966, Volume: 18, Issue:1 Topics: Animals; Hydrazines; In Vitro Techniques; Metaraminol; Methyldopa; Monoamine Oxidase; Myocardium; Norepinephrine; Rats; Reserpine	1966
Studies on the metabolism of 5-hydroxytryptamine (serotonin). IV. The effect of various drugs on the in vivo hydroxylation of tryptophan by the brain tissue. Life sciences, 1965, Volume: 4, Issue:18 Topics: Animals; Birds; Brain; Chromatography; Hydrazines; In Vitro Techniques; Intestine, Small; Kidney; Liver; Methotrexate; Methyldopa; Mixed Function Oxygenases; Myocardium; Rats; Reserpine; Serotonin; Tryptophan	1965
Drug-induced changes in monoamine levels in the sympathetic adrenergic ganglion cells and terminals. A histochemical study. Acta physiologica Scandinavica, 1965, Volume: 65, Issue:3 Topics: 5-Hydroxytryptophan; Animals; Catecholamines; Dihydroxyphenylalanine; Dopamine; Ephedrine; Ganglia, Autonomic; Hydrazines; Methyldopa; Microscopy, Fluorescence; Nerve Endings; Neurochemistry; Nialamide; Pargyline; Rats; Reserpine; Tranylcypromine; Tyrosine	1965
In vitro inhibition of noradrenaline-3H uptake by reserpine and tetrabenazine in mouse cerebral cortex tissues. Acta pharmacologica et toxicologica, 1966, Volume: 24, Issue:1 Topics: Animals; Cerebral Cortex; Chlorpromazine; Diiodotyrosine; Hydrazines; In Vitro Techniques; Methyldopa; Mice; Norepinephrine; Normetanephrine; Pargyline; Reserpine; Tetrabenazine; Tranylcypromine; Tritium	1966
The action of 2-amino-tetralin (beta-tetrahydronaphthylamine) on the metabolism of 5-hydroxytryptamine in the brain of the mouse. British journal of pharmacology and chemotherapy, 1967, Volume: 29, Issue:3 Topics: Animals; Brain; Hydrazines; Hydroxyindoleacetic Acid; Injections, Intraperitoneal; Male; Methyldopa; Mice; Naphthalenes; Serotonin; Tryptophan	1967
Hypertension: current trends in diagnosis and treatment. Geriatrics, 1967, Volume: 22, Issue:11 Topics: Aortic Coarctation; Azides; Cushing Syndrome; Ganglionic Blockers; Humans; Hydrazines; Hyperaldosteronism; Hypertension; Hypertension, Malignant; Hypertension, Renal; Methyldopa; Renal Artery Obstruction; Reserpine; Trimethaphan	1967
The influence of bretylium on the interactions of infused sympathomi- metic amines and tyramine in the reserpine-treated pithed rat. British journal of pharmacology and chemotherapy, 1968, Volume: 32, Issue:2 Topics: Animal Population Groups; Animals; Blood Pressure; Bretylium Compounds; Decerebrate State; Drug Synergism; Female; Heart Rate; Hydrazines; Methyldopa; Monoamine Oxidase Inhibitors; Nialamide; Norepinephrine; Normetanephrine; Rats; Reserpine; Sympathomimetics; Tritium; Tyramine	1968
[On the choice of hypotensive drugs with reference to their cardiac effect]. Schweizerische medizinische Wochenschrift, 1967, Dec-30, Volume: 97, Issue:52 Topics: Antihypertensive Agents; Diuretics; Ganglionic Blockers; Guanethidine; Heart; Humans; Hydrazines; Hypertension; Imidazoles; Methyldopa; Monoamine Oxidase Inhibitors; Reserpine; Triamterene	1967
The effect of various agents on the pressor response to dopa in the anesthetized dog. European journal of pharmacology, 1969, Volume: 8, Issue:1 Topics: Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Arteries; Blood Pressure; Bretylium Compounds; Cocaine; Cresols; Dihydroxyphenylalanine; Dogs; Dopamine Antagonists; Female; Guanethidine; Hydrazines; Male; Methyldopa; Norepinephrine; Oxidoreductases; Stimulation, Chemical; Thiocarbamates	1969
The mode of action of insulin potentiation by mebanazine. The Journal of pharmacy and pharmacology, 1970, Volume: 22, Issue:4 Topics: Animals; Antihypertensive Agents; Brain Chemistry; Drug Synergism; Glycogen; Guanethidine; Guanidines; Hydrazines; Hypoglycemia; Insulin; Liver; Male; Methyldopa; Monoamine Oxidase Inhibitors; Myocardium; Norepinephrine; Octopamine; Rats; Reserpine; Tranylcypromine	1970
Potentiation of the central actions of 5-hydroxytryptophan in rabbits by DL-alpha-hydrazino-alpha-methyldopa. The Journal of pharmacy and pharmacology, 1970, Volume: 22, Issue:5 Topics: 5-Hydroxytryptophan; Animals; Behavior, Animal; Body Temperature; Brain Chemistry; Central Nervous System; Drug Synergism; Hydrazines; Methyldopa; Rabbits	1970
4,4,6-trimethyl-3,4-dihydropyrimidine-2-thiol, an effective inhibitor of dopamine-beta-hydroxylation in vivo. Biochemical pharmacology, 1971, Volume: 20, Issue:1 Topics: Acetaldehyde; Amino Alcohols; Animals; Benzyl Compounds; Blood Pressure; Brain Chemistry; Carbon Isotopes; Cattle; Dihydroxyphenylalanine; Disulfiram; Dopamine; Ethanol; Ethylamines; Female; Heart; Hydrazines; Iodine; Male; Metaraminol; Methyldopa; Methyltyrosines; Mice; Mixed Function Oxygenases; Monoamine Oxidase Inhibitors; Myocardium; Norepinephrine; Normetanephrine; Propylthiouracil; Pyrimidines; Rats; Reserpine; Stereoisomerism; Sulfhydryl Compounds; Thyroid Gland; Tyramine	1971
[Clinical pharmacology of hypertension]. Wiener klinische Wochenschrift, 1971, Sep-17, Volume: 83, Issue:37 Topics: Adrenergic beta-Antagonists; Blood Pressure; Bretylium Compounds; Cardiac Volume; Diuretics; Ganglionic Blockers; Guanethidine; Humans; Hydrazines; Hypertension; Imidazoles; Methyldopa; Monoamine Oxidase Inhibitors; Phytotherapy; Plants, Medicinal; Plants, Toxic; Rauwolfia; Veratrum; Water-Electrolyte Balance	1971
Evidence for a centrally mediated hypotensive effect of L-dopa in the rat. The Journal of pharmacy and pharmacology, 1970, Volume: 22, Issue:3 Topics: Animals; Blood Pressure; Central Nervous System; Depression, Chemical; Dihydroxyphenylalanine; Disulfides; Disulfiram; Dopamine beta-Hydroxylase; Hydrazines; Imidazoles; Male; Methyldopa; Rats; Rats, Inbred Strains	1970
The role of pharmacologically-active amines in resistance to Trichostrongylus colubriformis in the guinea-pig. Immunology, 1971, Volume: 21, Issue:6 Topics: 5-Hydroxytryptophan; Animals; Basophils; Eosinophils; Feces; Guinea Pigs; Histamine; Histamine H1 Antagonists; Histidine; Hydrazines; Immunity; Immunization; Lymph Nodes; Lymphocytes; Methyldopa; Methysergide; Parasite Egg Count; Promethazine; Pyrroles; Reserpine; Serotonin; Transplantation, Homologous; Trichostrongyloidiasis; Tryptophan	1971
Inhibition of catechol-O-methyl transferase by L-dopa and decarboxylase inhibitors. The Journal of pharmacy and pharmacology, 1972, Volume: 24, Issue:1 Topics: Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Catechols; Dihydroxyphenylalanine; Hydrazines; Liver; Methyldopa; Methyltransferases; Norepinephrine; Normetanephrine; Propionates; Pyrogallol; Rats; Tritium	1972
Aggression in rats treated with dopa and 6-hydroxydopamine. The Journal of pharmacy and pharmacology, 1972, Volume: 24, Issue:4 Topics: Adrenal Glands; Aggression; Animals; Apomorphine; Dihydroxyphenylalanine; Humans; Hydrazines; Methyldopa; Phenethylamines; Propionates; Rats; Thiocarbamates; Tyrosine 3-Monooxygenase	1972
Dopamine: mediator of brain polysome disaggregation after L-dopa. Science (New York, N.Y.), 1972, Aug-18, Volume: 177, Issue:4049 Topics: Animals; Benzyl Compounds; Brain; Brain Chemistry; Carboxy-Lyases; Dihydroxyphenylalanine; Dopamine; Hydrazines; Injections, Intraperitoneal; Male; Methyldopa; Norepinephrine; Rats; Rats, Inbred Strains; Ribosomes; S-Adenosylmethionine; Serine	1972
On the localization of the hypotensive effect of L-dopa. The Journal of pharmacy and pharmacology, 1972, Volume: 24, Issue:6 Topics: Animals; Arteries; Blood Pressure; Brain Chemistry; Cordotomy; Decerebrate State; Depression, Chemical; Dihydroxyphenylalanine; Dopamine; Drug Synergism; Hydrazines; Male; Methyldopa; Norepinephrine; Propionates; Rats	1972
The treatment of malignant hypertension and hypertensive emergencies. A statement by the AMA committee on hypertension. JAMA, 1974, Jun-24, Volume: 228, Issue:13 Topics: Administration, Oral; Antihypertensive Agents; Blood Pressure; Diazoxide; Drug Evaluation; Emergencies; Female; Humans; Hydrazines; Hypertension, Malignant; Hypotension; Injections, Intramuscular; Injections, Intravenous; Male; Methods; Methyldopa; Pentolinium Tartrate; Phentolamine; Reserpine; Trimethaphan	1974
Inhibition of uridine incorporation in proerythroblasts patients with alpha-methyldopa induced haemolytic anaemia. British journal of haematology, 1974, Volume: 27, Issue:4 Topics: Anemia, Hemolytic; Animals; Autoradiography; Coombs Test; Erythrocytes; Female; Hematopoietic Stem Cells; Hemoglobins; Humans; Hydrazines; Hypertension; Injections, Intraperitoneal; Male; Methyldopa; Mice; Middle Aged; Osmotic Fragility; Prednisolone; Reticulocytes; Thymidine; Tritium; Uridine	1974
L- -methyl- -hydrazino- -(3,4-dihydroxyphenyl)propionic acid: relative lack of antidecarboxylase activity in adrenals. Science (New York, N.Y.), 1972, May-26, Volume: 176, Issue:4037 Topics: 5-Hydroxytryptophan; Adrenal Glands; Animals; Brain Chemistry; Carboxy-Lyases; Catechols; Female; Hydrazines; Kidney; Methyldopa; Pargyline; Propionates; Rats; Serotonin; Time Factors	1972
Uptake and utilization of ( 3 H-)5-hydroxytryptophan by brain tissue during development. Neuropharmacology, 1972, Volume: 11, Issue:3 Topics: 5-Hydroxytryptophan; Animals; Brain; Brain Stem; Carboxy-Lyases; Diencephalon; Hydrazines; Hydroxyindoleacetic Acid; Kinetics; Methyldopa; Rats; Serotonin; Telencephalon; Tritium	1972
Inhibition of dopa decarboxylation by RO4-4602, MK 485 and MK 486 in human liver homogenates. Archives internationales de pharmacodynamie et de therapie, 1972, Volume: 198, Issue:1 Topics: 5-Hydroxytryptophan; Aromatic Amino Acid Decarboxylase Inhibitors; Benzyl Compounds; Binding Sites; Carbon Isotopes; Copper; Decarboxylation; Depression, Chemical; Dihydroxyphenylalanine; Humans; Hydrazines; In Vitro Techniques; Kinetics; Liver; Methyldopa; Serine	1972
Release of ( 3 H)dopamine by L-5-hydroxytryptophan. Brain research, 1972, Oct-27, Volume: 45, Issue:2 Topics: 5-Hydroxytryptophan; Animals; Basal Ganglia; Corpus Striatum; Dopamine; Hydrazines; Male; Methyldopa; Rats; Serotonin; Synaptic Vesicles; Tritium	1972
Effect of L-DOPA and analogues on central dopamine and noradrenaline mechanisms. Advances in neurology, 1974, Volume: 5 Topics: 5-Hydroxytryptophan; Acetamides; Animals; Apomorphine; Brain Chemistry; Clonidine; Corpus Striatum; Dopamine; Hydrazines; Levodopa; Methyldopa; Methyltyrosines; Movement; Nialamide; Norepinephrine; Octopamine; Rats; Receptors, Drug; Reflex; Reserpine; Spinal Cord; Stimulation, Chemical; Tyramine; Tyrosine	1974
Tremor and involuntary movements in monkeys: effect of L-dopa and of a dopamine receptor stimulating agent. Science (New York, N.Y.), 1973, Feb-23, Volume: 179, Issue:4075 Topics: 5-Hydroxytryptophan; Animals; Benzyl Compounds; Dihydroxyphenylalanine; Dioxoles; Drug Interactions; Electroencephalography; Haloperidol; Haplorhini; Humans; Hydrazines; Hyperkinesis; Injections, Intraperitoneal; Methyldopa; Methyltyrosines; Picolinic Acids; Piperazines; Pyrimidines; Tremor	1973
Effects of peripheral aromatic L-amino acids decarboxylase inhibitor on L-(2- 14 C)-3,4-dihydroxyphenylalanine metabolism in man. Biochemical pharmacology, 1972, Aug-01, Volume: 21, Issue:15 Topics: Amino Acids; Carbon Isotopes; Carboxy-Lyases; Catecholamines; Dihydroxyphenylalanine; Dopamine; Hydrazines; Methyldopa; Phenols; Phenylacetates; Time Factors	1972
The action of L(-)-dopa on baroreflexes in Parkinsonism. Clinical science, 1972, Volume: 43, Issue:6 Topics: Adult; Aged; Aromatic Amino Acid Decarboxylase Inhibitors; Blood Pressure; Dihydroxyphenylalanine; Female; Humans; Hydrazines; Male; Methyldopa; Middle Aged; Parkinson Disease; Posture; Pressoreceptors; Reflex; Valsalva Maneuver	1972
Modification of levodopa effect by systemic decarboxylase inhibition. Archives of neurology, 1973, Volume: 28, Issue:2 Topics: Arrhythmias, Cardiac; Carboxy-Lyases; Dihydroxyphenylalanine; Dopamine; Drug Synergism; Electrocardiography; Humans; Hydrazines; Methyldopa; Parkinson Disease	1973
Action of levodopa on the blood pressure of conscious rabbits. Clinical science, 1973, Volume: 44, Issue:4 Topics: Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Blood Pressure; Dihydroxyphenylalanine; Hydrazines; Iproniazid; Methyldopa; Rabbits	1973
[Medical treatment of arterial hypertension in adults]. La Revue du praticien, 1973, Feb-11, Volume: 23, Issue:9 Topics: Adult; Antihypertensive Agents; Clonidine; Diet, Sodium-Restricted; Guanethidine; Humans; Hydrazines; Hypertension; Male; Methyldopa; Reserpine; Spironolactone; Time Factors	1973
[Treatment of Parkinson's syndrome with L-dopa and its methylated derivatives: 3-OMD and 4-OMD associated with a decarboxylase inhibitor. Clinical and biochemical study]. Schweizerische medizinische Wochenschrift, 1973, Oct-20, Volume: 103, Issue:42 Topics: Aged; Benserazide; Carboxy-Lyases; Depression; Dihydroxyphenylalanine; Drug Evaluation; Drug Therapy, Combination; Humans; Hydrazines; Methyldopa; Middle Aged; Paralysis; Parkinson Disease; Sleep Wake Disorders; Time Factors	1973
Urinary excretion of noradrenaline after treatment with alpha-methyldopa: inhibition by a central nervous mechanism. Acta physiologica Scandinavica, 1974, Volume: 90, Issue:1 Topics: Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Carbidopa; Depression, Chemical; Epinephrine; Hydrazines; Injections, Intraperitoneal; Male; Methyldopa; Norepinephrine; Rats; Tritium	1974
[Relationship between the antihypertensive activity of methyldopa and the appearance of its metabolites in the heart and brain of the hypertensive rat]. Archives internationales de pharmacodynamie et de therapie, 1974, Volume: 207, Issue:2 Topics: Animals; Antihypertensive Agents; Aromatic Amino Acid Decarboxylase Inhibitors; Benserazide; Biotransformation; Blood Pressure; Brain; Disulfides; Disulfiram; Dopamine; Dopamine beta-Hydroxylase; Hydrazines; Hypertension; Imidazoles; Male; Methane; Methyldopa; Myocardium; Norepinephrine; Rats; Sympatholytics; Time Factors; Tritium	1974
"On-off" phenomenon with levodopa therapy in Parkinsonism. Clinical and pharmacologic correlations and the effect of intramuscular pyridoxine. Neurology, 1974, Volume: 24, Issue:5 Topics: Adult; Carbidopa; Dihydroxyphenylalanine; Drug Synergism; Evaluation Studies as Topic; Female; Homovanillic Acid; Humans; Hydrazines; Injections, Intramuscular; Male; Methyldopa; Middle Aged; Movement Disorders; Parkinson Disease; Pyridoxine	1974
Block of cerebral actions of L-dopa with methyl receptor substances. Nature, 1971, Jun-25, Volume: 231, Issue:5304 Topics: Age Factors; Animals; Apomorphine; Aromatic Amino Acid Decarboxylase Inhibitors; Brain; Brain Chemistry; Dihydroxyphenylalanine; Dopamine; Drug Synergism; Hydrazines; Lethal Dose 50; Methyldopa; Mice; Phenylacetates; Postural Balance; Time Factors	1971
[Current treatment of cardiovascular diseases with special reference to long-term therapy]. Zeitschrift fur arztliche Fortbildung, 1967, Jun-15, Volume: 61, Issue:12 Topics: Angina Pectoris; Anti-Bacterial Agents; Anticoagulants; Antihypertensive Agents; Arrhythmias, Cardiac; Diet Therapy; Digitalis Glycosides; Heart Diseases; Heart Failure; Humans; Hydrazines; Hypertension; Long-Term Care; Methyldopa; Phytotherapy; Plants, Medicinal; Rauwolfia; Rheumatic Fever; Sympatholytics; Sympathomimetics	1967
Histamine formation in rat brain in vivo: effects of histidine loads. Journal of neurochemistry, 1972, Volume: 19, Issue:3 Topics: Animals; Benzyl Compounds; Brain; Brain Chemistry; Carboxy-Lyases; Cycloheximide; Enzyme Activation; Histamine; Histidine; Hydrazines; Hypothalamus; Male; Methyldopa; Rats; Serine	1972
The induction and antagonism of central nervous system stimulant-induced stereotyped behavior in the cat. European journal of pharmacology, 1972, Volume: 18, Issue:1 Topics: Amphetamine; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Behavior, Animal; Benzyl Compounds; Cats; Central Nervous System; Cocaine; Dextroamphetamine; Dihydroxyphenylalanine; Drug Antagonism; Hydrazines; Methyldopa; Methylphenidate; Methyltyrosines; Pemoline; Reserpine; Serine; Stimulation, Chemical	1972
Degeneration of central and peripheral noradrenaline neurons produced by 6-hydroxy-DOPA. Journal of neurochemistry, 1972, Volume: 19, Issue:6 Topics: Alcohols; Animals; Animals, Newborn; Basal Ganglia; Brain; Carbon Isotopes; Cerebral Cortex; Dihydroxyphenylalanine; Heart Atria; Histocytochemistry; Hydrazines; Iris; Male; Metaraminol; Methyldopa; Mice; Microscopy, Fluorescence; Neurons; Nialamide; Norepinephrine; Receptors, Adrenergic; Receptors, Drug; Sensory Receptor Cells; Serotonin; Tritium	1972
The mode of action of -methyldopa. British journal of pharmacology, 1972, Volume: 45, Issue:1 Topics: Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Disulfiram; Hydrazines; Hypertension; Methyldopa; Rats; Thiocarbamates	1972
Dependence of arterial pressure on intravascular volume in treated hypertensive patients. The New England journal of medicine, 1972, Apr-20, Volume: 286, Issue:16 Topics: Adult; Aged; Arteries; Blood Pressure; Female; Furosemide; Guanethidine; Humans; Hydrazines; Hydrochlorothiazide; Hypertension; Male; Methyldopa; Middle Aged; Plasma Volume; Propranolol; Spironolactone; Triamterene	1972
Levadopa and pyridoxine. JAMA, 1972, Mar-27, Volume: 219, Issue:13 Topics: Animals; Brain; Carboxy-Lyases; Decarboxylation; Dihydroxyphenylalanine; Drug Interactions; Humans; Hydrazines; Injections, Intraperitoneal; Methyldopa; Mice; Parkinson Disease; Propionates; Pyridoxine	1972
Effects of L-dopa on accumulation and efflux of monoamines in particles of rat brain homogenates. The Journal of pharmacology and experimental therapeutics, 1972, Volume: 183, Issue:2 Topics: Amino Acids; Animals; Brain; Brain Chemistry; Carbon Isotopes; Dihydroxyphenylalanine; Dopamine; Hydrazines; Male; Methyldopa; Microsomes; Mitochondria; Myelin Sheath; Norepinephrine; Rats; Serotonin; Stimulation, Chemical; Synaptosomes; Tritium	1972
[Hypertension--malignant hypertension]. Naika. Internal medicine, 1971, Volume: 27, Issue:6 Topics: Diuretics; Hexamethonium Compounds; Humans; Hydrazines; Hypertension, Malignant; Male; Methyldopa; Middle Aged; Reserpine; Triamterene	1971
[Parkinsonism and plasma metabolism of dihydroxyphenylalanine administered with an inhibitor of decarboxylase]. Clinica chimica acta; international journal of clinical chemistry, 1971, Volume: 33, Issue:1 Topics: Aromatic Amino Acid Decarboxylase Inhibitors; Dihydroxyphenylalanine; Humans; Hydrazines; Hydrochloric Acid; Methyldopa; Parkinson Disease; Phenylacetates; Sodium Hydroxide	1971
L-dopa and cardiac arrhythmias. The New England journal of medicine, 1971, Dec-16, Volume: 285, Issue:25 Topics: Arrhythmias, Cardiac; Dihydroxyphenylalanine; Humans; Hydrazines; Methyldopa; Parkinson Disease; Propionates	1971
L-3,4-dihydroxyphenylalanine-induced of norepinephrine from the rat heart. Biochemical pharmacology, 1971, Volume: 20, Issue:12 Topics: Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Chlorisondamine; Dihydroxyphenylalanine; Dopamine; Female; Heart; Hydrazines; Methyldopa; Myocardium; Nerve Endings; Norepinephrine; Rats; Stimulation, Chemical; Sympathetic Nervous System; Tritium	1971
Histamine in rat brain: sensitive assay of endogenous levels, formation in vivo and lowering by inhibitors of histidine decarboxylase. The Journal of pharmacology and experimental therapeutics, 1971, Volume: 179, Issue:3 Topics: Animals; Brain; Brain Chemistry; Carbon Isotopes; Carboxy-Lyases; Chromatography, Ion Exchange; Histamine; Histidine; Hydrazines; Hypothalamus; Kinetics; Male; Methyldopa; Methyltransferases; Rats; Rats, Inbred Strains; Temperature; Tritium	1971
Modification of L-dopa therapy of Parkinsonism by alpha-methyldopa hydrazine (MK-486). Transactions of the American Neurological Association, 1971, Volume: 96 Topics: Dihydroxyphenylalanine; Drug Synergism; Humans; Hydrazines; Methyldopa; Parkinson Disease	1971
Levodopa in the treatment of Parkinsonism. JAMA, 1971, Dec-27, Volume: 218, Issue:13 Topics: Animals; Apomorphine; Aromatic Amino Acid Decarboxylase Inhibitors; Brain; Dihydroxyphenylalanine; Dopamine; Esters; Humans; Hydrazines; Manganese Poisoning; Methylation; Methyldopa; Mice; Movement; Parkinson Disease; Parkinson Disease, Secondary; Phenylacetates	1971
Depressor responses of the spontaneously hypertensive rats to the anti-hypertensive agents. Japanese journal of pharmacology, 1969, Volume: 19, Issue:3 Topics: Anesthesia; Animals; Antihypertensive Agents; Blood Pressure; Depression, Chemical; Guanethidine; Heart Rate; Hexamethonium Compounds; Hydrazines; Hypertension; Injections, Subcutaneous; Methyldopa; Protoveratrines; Rats; Reserpine	1969
Cerebrospinal fluid monoamine metabolites and peripheral decarboxylase inhibitors in parkinsonism. Neurology, 1970, Volume: 20, Issue:12 Topics: 5-Hydroxytryptophan; Adult; Aromatic Amino Acid Decarboxylase Inhibitors; Dihydroxyphenylalanine; Drug Synergism; Female; Humans; Hydrazines; Hydroxyindoleacetic Acid; Methyldopa; Middle Aged; Parkinson Disease; Phenylacetates	1970
Properties and regional distribution of histidine decarboxylase in rat brain. Journal of neurochemistry, 1970, Volume: 17, Issue:11 Topics: Animals; Basal Ganglia; Benzene; Brain; Carboxy-Lyases; Centrifugation; Cerebellum; Cerebral Cortex; Cresols; Fluorometry; Hippocampus; Histidine; Hydrazines; Hydrogen-Ion Concentration; Hypothalamus; Limbic System; Male; Medulla Oblongata; Mesencephalon; Methyldopa; Rats; Spinal Cord	1970
Effects of L-dopa on efflux of cerebral monoamines from synaptosomes. Nature, 1971, Apr-02, Volume: 230, Issue:5292 Topics: Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Carbon Isotopes; Dihydroxyphenylalanine; Dopamine; Hydrazines; Methyldopa; Nerve Endings; Neurosecretion; Norepinephrine; Propionates; Rats; Serotonin; Synapses; Tritium	1971
Effect of different dopa decarboxylase inhibitors on the hypotensive response to alpha-methyldopa in rats. British journal of pharmacology, 1968, Volume: 34, Issue:1 Topics: Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Blood Pressure; Brain Chemistry; Catecholamines; Hydrazines; Methyldopa; Muscles; Myocardium; Rats	1968
Histamine formation in normal and totally-gastrectomised rats. Archives internationales de pharmacodynamie et de therapie, 1968, Volume: 174, Issue:1 Topics: Animals; Carbon Isotopes; Diet; Female; Gastrectomy; Gastric Mucosa; Histamine; Hydrazines; Methyldopa; Rats	1968
Influence of drugs on the temperature-lowering effect of harmaline. European journal of pharmacology, 1968, Volume: 4, Issue:1 Topics: Alkaloids; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Body Temperature Regulation; Brain; Female; Hydrazines; Hypothermia; Indoles; Male; Methyldopa; Methyltyrosines; Monoamine Oxidase Inhibitors; Norepinephrine; Picolines; Rats; Reserpine; Sensory Receptor Cells; Serotonin; Serotonin Antagonists; Thermography; Time Factors; Uterus	1968
[Medical therapy of arterial hypertension]. Cardiologia pratica, 1968, Volume: 19, Issue:5 Topics: Antihypertensive Agents; Arteries; Diuretics; Guanethidine; Humans; Hydrazines; Hypertension; Mecamylamine; Methyldopa; Phytotherapy; Plants, Medicinal; Rauwolfia; Reserpine	1968
Drug-induced changes of extracerebral dopa metabolism in man. Archives of neurology, 1969, Volume: 20, Issue:2 Topics: Blood-Brain Barrier; Carbon Isotopes; Dihydroxyphenylalanine; Humans; Hydrazines; Intestinal Absorption; Methyldopa; Phenylacetates	1969
Interaction of DOPA decarboxylase inhibitors with the effect of alpha-methyldopa on blood pressure and tissue monoamines in rats. Acta pharmacologica et toxicologica, 1969, Volume: 27, Issue:2 Topics: Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Blood Pressure; Brain Chemistry; Catecholamines; Dopamine; Drug Synergism; Hydrazines; Male; Methods; Methyldopa; Myocardium; Norepinephrine; Rats; Serotonin; Time Factors	1969
Effect of some drugs upon the histamine concentration of rat heart. Archives internationales de pharmacodynamie et de therapie, 1967, Volume: 166, Issue:1 Topics: Amines; Animals; Chlorpromazine; Guanethidine; Heart; Histamine; Histidine; Hydrazines; Iproniazid; Male; Methyldopa; Myocardium; Phenoxybenzamine; Rats; Tranylcypromine	1967
Alpha-methyl-DOPA induced mydriasis in the cat. Relationship between pupillary response and the oculomotor perfusate concentration of methyldopa and its metabolites. Naunyn-Schmiedeberg's archives of pharmacology, 1983, Volume: 324, Issue:3 Topics: Animals; Biogenic Amines; Bis(4-Methyl-1-Homopiperazinylthiocarbonyl)disulfide; Brain; Cats; Female; Hydrazines; Male; Methyldopa; Pupil	1983
Studies on the mechanism of methyl-dopa-induced mydriasis in the cat. Naunyn-Schmiedeberg's archives of pharmacology, 1982, Volume: 320, Issue:1 Topics: Animals; Bis(4-Methyl-1-Homopiperazinylthiocarbonyl)disulfide; Cats; Female; Hydrazines; Injections, Intraventricular; Male; Methyldopa; Mydriatics; Prazosin; Pupil; Time Factors; Yohimbine	1982
Inhibition of DOPA decarboxylase by the hydrazino analog of alpha-methylDOPA. Biochemical pharmacology, 1962, Volume: 11 Topics: Dopa Decarboxylase; Humans; Hydrazines; Inorganic Chemicals; Methyldopa; Organic Chemicals	1962
The effect of L-alpha-methyl DOPA and N-2-hydroxybenzyl-N-methyl hydrazine (NSD 1039) on the blood pressure of renal hypertensive rates. Life sciences (1962), 1963, Volume: 3 Topics: Blood Pressure; Dihydroxyphenylalanine; Hydrazines; Hypertension; Hypertension, Renal; Kidney; Methyldopa; Methylhydrazines	1963
OBSERVATIONS ON THE INHIBITION OF HISTAMINE FORMATION. The Journal of physiology, 1963, Volume: 169 Topics: Anti-Allergic Agents; Carbon Isotopes; Carboxy-Lyases; Chromatography; Cortisone; Enzyme Inhibitors; Gastric Juice; Histamine; Histamine H1 Antagonists; Histidine; Hydrazines; Mast Cells; Methyldopa; Physiology; Prednisolone; Pyridoxal Phosphate; Pyridoxine; Rats; Research; Urine	1963
[COMPARATIVE ACTION OF 2 DECARBOXYLASE INHIBITORS ON THE METABOLISM OF ENDOGENOUS AND EXOGENOUS 5-HYDROXYTRYPTAMINE]. Archives internationales de pharmacodynamie et de therapie, 1964, Jan-01, Volume: 147 Topics: 5-Hydroxytryptophan; Antihypertensive Agents; Brain; Carboxy-Lyases; Enzyme Inhibitors; Hydrazines; Metabolism; Methyldopa; Pharmacology; Rats; Research; Serotonin	1964
[ANTIHYPERTENSIVE PROPERTIES OF POLYTHIAZIDE]. Therapeutische Umschau. Revue therapeutique, 1963, Volume: 20 Topics: Antihypertensive Agents; Benzothiadiazines; Chlorthalidone; Diuretics; Hydrazines; Hypertension; Methyldopa; Polythiazide	1963
EFFECT OF MONOAMINE RELEASERS AND DECARBOXYLASE INHIBITORS ON ENDOGENOUS 5-HYDROXYINDOLE DERIVATIVES IN BRAIN. Biochemical pharmacology, 1964, Volume: 13 Topics: Brain; Brain Stem; Carboxy-Lyases; Chromatography; Enzyme Inhibitors; Fluorometry; Hydrazines; Hydroxyindoleacetic Acid; Indoleacetic Acids; Indoles; Methyldopa; Pharmacology; Rats; Research; Reserpine; Serotonin; Spectrophotometry; Tranquilizing Agents	1964
POTENT DECARBOXYLASE INHIBITORS. ANALOGS OF METHYLDOPA. Journal of medicinal chemistry, 1963, Volume: 6 Topics: Chemistry, Pharmaceutical; Dopa Decarboxylase; Enzyme Inhibitors; Hydrazines; Methyldopa; Organic Chemicals; Rats; Research	1963
[ACTION OF ALPHA-METHYL-HYDRAZINO-DOPA AND OF ITS PHOSPHO-5'-PYRIDOXAL HYDRAZINE ON AMINO ACID DECARBOXYLASES]. Journal of neurochemistry, 1964, Volume: 11 Topics: Amino Acids; Biochemical Phenomena; Biochemistry; Carboxy-Lyases; Dopa Decarboxylase; Glutamates; Hydrazines; Methyldopa; Monoamine Oxidase; Pharmacology; Phosphotransferases; Pyridoxal; Pyridoxal Phosphate; Research; Serotonin; Tyrosine Decarboxylase	1964
INHIBITION OF HISTAMINE SYNTHESIS IN THE RAT BY ALPHA-HYDRAZINO ANALOG OF HISTIDINE AND 4-BROMO-3-HYDROXY BENZYLOXYAMINE. Biochemical pharmacology, 1965, Volume: 14 Topics: Amines; Carboxy-Lyases; Enzyme Inhibitors; Germ-Free Life; Histamine; Histamine Release; Histidine; Hydrazines; Hydroxylamines; Mast Cells; Metabolism; Methyldopa; Myocardium; p-Methoxy-N-methylphenethylamine; Pharmacology; Rats; Research; Stomach; Urine	1965
URINARY HISTAMINE EXCRETION IN THE GASTRECTOMISED RAT. Life sciences (1962), 1965, Volume: 4 Topics: Carbon Isotopes; Carboxy-Lyases; Enzyme Inhibitors; Gastrectomy; Gastric Mucosa; Histamine; Histidine; Hydrazines; Hydroxylamines; Metabolism; Methyldopa; Pharmacology; Pylorus; Radiometry; Rats; Research; Thyroxine; Urine	1965
INHIBITION OF CEREBRAL DECARBOXYLASE AND BEHAVIOUR. International journal of neuropharmacology, 1964, Volume: 3 Topics: 5-Hydroxytryptophan; Animals; Behavior, Animal; Brain; Brain Chemistry; Carboxy-Lyases; Dopamine; Enzyme Inhibitors; Hydrazines; Metabolism; Methyldopa; Mice; Norepinephrine; Pharmacology; Research; Serotonin	1964