methyldopa has been researched along with homovanillic acid in 30 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 20 (66.67) | 18.7374 |
| 1990's | 5 (16.67) | 18.2507 |
| 2000's | 5 (16.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Davidson, L; Hornykiewicz, O; Lloyd, KG | 1 |
| Cier, JF; Miachon, S; Peyrin, L | 1 |
| Comi, R; Fahn, S; Prasad, AL; Snider, SR | 1 |
| Deruaz, D; Gjessing, L; Greffe, J; Guilluy, R; Mathieu, P | 1 |
| Geissbühler, F; Widmer, J | 1 |
| Maître, L; Waldmeier, PC | 1 |
| Charvet, JC; Greffe, J; Mathieu, P | 1 |
| Cheng, LK; Fung, HL | 1 |
| Buckingham, RL; Radulovacki, M | 1 |
| Männistö, PT; Tuomainen, P; Tuominen, RK | 1 |
| De Klippel, N; Deleu, D; Ebinger, G; Herregodts, P; Michotte, Y; Sarre, S | 1 |
| Baumann, PA; Bischoff, S; Bittiger, H; Feldtrauer, JJ; Hauser, K; von Sprecher, G; Waldmeier, PC | 1 |
| Davoudi, H; Durso, R; Feldman, RG; Szabo, G | 1 |
| Hornykiewicz, O | 1 |
| Constantinidis, J | 1 |
| Dinapoli, RP; Muenter, MD; Sharpless, NS; Tyce, GM | 1 |
| Fahn, S; Prasad, AL | 1 |
| Uretsky, NJ | 1 |
| Fahn, S | 1 |
| Lindén, IB | 1 |
| Curzon, G; Hutson, PH; Kantamaneni, BD; Sarna, GS | 1 |
| Curzon, G; Hutson, PH; Sarna, GS | 1 |
| Boulton, AA; Juorio, AV | 1 |
| Carey, RJ; Huston, JP; Pinheiro-Carrera, M; Tomaz, C | 1 |
| Andre, MH; Bruguerolle, B; Grignon, S | 1 |
| Forsberg, M; Gogos, JA; Huotari, M; Hyttinen, J; Karayiorgou, M; Koponen, O; Männistö, PT; Raasmaja, A | 1 |
| Höcht, C; Opezzo, JA; Taira, CA | 1 |
| Allen, RP; Earley, CJ; Hyland, K | 1 |
| Högl, B | 1 |
1 review(s) available for methyldopa and homovanillic acid
| Article | Year |
|---|---|
Parkinson's disease: from brain homogenate to treatment.
Topics: Animals; Brain; Caudate Nucleus; Corpus Striatum; Dihydroxyphenylalanine; Dopa Decarboxylase; Dopamine; Dose-Response Relationship, Drug; Globus Pallidus; Homovanillic Acid; Humans; Methyldopa; Parkinson Disease; Phenylacetates; Receptors, Drug; Substantia Nigra; Tyrosine 3-Monooxygenase | 1973 |
29 other study(ies) available for methyldopa and homovanillic acid
| Article | Year |
|---|---|
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
The neurochemistry of Parkinson's disease: effect of L-dopa therapy.
Topics: Aged; Brain; Catechol O-Methyltransferase; Dihydroxyphenylalanine; Dopa Decarboxylase; Dopamine; Female; Homovanillic Acid; Humans; Levodopa; Male; Methyldopa; Middle Aged; Monoamine Oxidase; Parkinson Disease; Tyrosine 3-Monooxygenase | 1975 |
[Effects of precursors and metabolites of catecholamines on motricity of isolated rat duodenum. Particular reference to dopamine].
Topics: Animals; Catecholamines; Dihydroxyphenylalanine; Dopamine; Duodenum; Epinephrine; Gastrointestinal Motility; Homovanillic Acid; Male; Metanephrine; Methyldopa; Norepinephrine; Normetanephrine; Rats | 1979 |
Effect of a catechol-O-methyl transferase inhibitor, U-0521, with levodopa administration.
Topics: Animals; Behavior, Animal; Brain; Catechol O-Methyltransferase Inhibitors; Dihydroxyphenylalanine; Dopamine; Dose-Response Relationship, Drug; Drug Interactions; Homovanillic Acid; Levodopa; Male; Methyldopa; Propiophenones; Rats; Time Factors | 1979 |
N-Acetyl, 4-O-methyldopa, a major metabolite of L-4-O-methyldopa in man and rat.
Topics: Acetylation; Adult; Animals; Dopamine; Female; Homovanillic Acid; Humans; Isomerism; Lactates; Levodopa; Male; Methyldopa; Pyruvates; Rats; Species Specificity | 1976 |
[Urinary excretion of 3,4-dihydroxyphenyl-alanine, 3-O-methyldopa, dopamine and homovanillic acid in man. Effects of an inhibitor of decarboxylase of aromatic amino acids (Benserazide) (author's transl)].
Topics: Adult; Benserazide; Dihydroxyphenylalanine; Dopamine; Female; Homovanillic Acid; Humans; Hydrazines; Male; Methyldopa; Phenylacetates; Time Factors | 1976 |
Comparison of short and long-lasting effects of pargyline on cerebral dopamine metabolism.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain; Cisterna Magna; Corpus Striatum; Dopamine; Female; Homovanillic Acid; Injections; Injections, Intravenous; Levodopa; Methyldopa; Monoamine Oxidase; Pargyline; Rats; Time Factors; Tyrosine | 1976 |
The 4-o-methyl metabolites of catecholamines. Homo-iso-vanillic acid in rat urine and brain; urinary iso-vanyl compounds after intraperitoneal administration of dopamine and of dopamine precursors and derivatives.
Topics: Animals; Brain Chemistry; Catecholamines; Chromatography, Paper; Dihydroxyphenylalanine; Dopamine; Fasting; Female; Homovanillic Acid; Indicators and Reagents; Isomerism; Male; Methyldopa; Phenols; Phenylacetates; Rats | 1975 |
Effects of chronic oral administration on the disposition of laevodopa and its major metabolites in the plasma of the rat.
Topics: 3,4-Dihydroxyphenylacetic Acid; Administration, Oral; Animals; Catecholamines; Homovanillic Acid; Levodopa; Male; Methyldopa; Rats; Time Factors; Vanilmandelic Acid | 1975 |
The selective effects of alpha-methyl aromatic amino acids on brain monoamine metabolites and behavior in cats.
Topics: Amino Acids; Animals; Behavior, Animal; Biogenic Amines; Brain; Cats; Electroencephalography; Homovanillic Acid; Hydroxyindoleacetic Acid; Methyldopa; Methyltyrosines; Time Factors | 1975 |
Different in vivo properties of three new inhibitors of catechol O-methyltransferase in the rat.
Topics: Amidines; Animals; Benzophenones; Biogenic Monoamines; Brain; Carbidopa; Catechol O-Methyltransferase Inhibitors; Catechols; Corpus Striatum; Homovanillic Acid; Hypothalamus; Levodopa; Male; Methyldopa; Nitriles; Nitrophenols; Pyridones; Rats; Rats, Inbred Strains; Tolcapone | 1992 |
High-performance liquid chromatography with electrochemical detection for the determination of levodopa, catecholamines and their metabolites in rat brain dialysates.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain Chemistry; Catecholamines; Caudate Nucleus; Chromatography, High Pressure Liquid; Dihydroxyphenylalanine; Dopamine; Epinephrine; Homovanillic Acid; Injections, Intraperitoneal; Levodopa; Male; Methyldopa; Norepinephrine; Rats; Rats, Inbred Strains; Substantia Nigra | 1992 |
CGP 28014, a new inhibitor of cerebral catechol-O-methylation with a non-catechol structure.
Topics: 3,4-Dihydroxyphenylacetic Acid; Amidines; Animals; Brain; Catechol O-Methyltransferase Inhibitors; Catechols; Clorgyline; Corpus Striatum; Female; Homovanillic Acid; In Vitro Techniques; Male; Methylation; Methyldopa; Neurotransmitter Agents; Pyridones; Pyrogallol; Rats; Rats, Inbred Strains; Tropolone | 1990 |
Magnitude of response to levodopa in Parkinson disease as it relates to peripheral and central measurements of levodopa and associated metabolites.
Topics: Aged; Carbidopa; Drug Combinations; Homovanillic Acid; Humans; Levodopa; Male; Methyldopa; Middle Aged; Parkinson Disease | 1989 |
[Monoamines and choreic syndromes].
Topics: Amines; Butyrophenones; Chorea; Diazepam; Dihydroxyphenylalanine; Dopamine; Ganglia; Globus Pallidus; Homovanillic Acid; Humans; Huntington Disease; Mental Disorders; Methyldopa; Methyltyrosines; Models, Neurological; Movement Disorders; Phenothiazines; Physostigmine; Reserpine; Thalamus; Tranquilizing Agents; Tyrosine | 1972 |
Dopa, 3-O-methyldopa, and metabolites in urine during oral L-3-O-methyldopa therapy.
Topics: Administration, Oral; Autoanalysis; Catecholamines; Dealkylation; Decarboxylation; Dihydroxyphenylalanine; Fluorometry; Homovanillic Acid; Humans; Lactates; Male; Methoxyhydroxyphenylglycol; Methyldopa; Parkinson Disease; Vanilmandelic Acid | 1974 |
3-O-methyl metabolites of catecholamines: automated fluorometric assay and their plasma levels in patients receiving levodopa and carbidopa.
Topics: Aromatic Amino Acid Decarboxylase Inhibitors; Autoanalysis; Blood-Brain Barrier; Brain Chemistry; Carbidopa; Chromatography, Ion Exchange; Dihydroxyphenylalanine; Dopamine; Evaluation Studies as Topic; Homovanillic Acid; Humans; Methods; Methyldopa; Microchemistry; Phenylacetates; Spectrometry, Fluorescence; Time Factors | 1974 |
Effect of alpha-methyldopa on the metabolism of dopamine in the striatum of the rat.
Topics: Animals; Brain Chemistry; Chromatography, Ion Exchange; Corpus Striatum; Dopamine; Homovanillic Acid; Hydroxydopamines; Male; Methyldopa; Monoamine Oxidase; Pargyline; Phenylacetates; Rats; Time Factors; Tritium; Tyrosine | 1974 |
"On-off" phenomenon with levodopa therapy in Parkinsonism. Clinical and pharmacologic correlations and the effect of intramuscular pyridoxine.
Topics: Adult; Carbidopa; Dihydroxyphenylalanine; Drug Synergism; Evaluation Studies as Topic; Female; Homovanillic Acid; Humans; Hydrazines; Injections, Intramuscular; Male; Methyldopa; Middle Aged; Movement Disorders; Parkinson Disease; Pyridoxine | 1974 |
Effects of 3,4-dihydroxyphenylpyruvic acid and L-glutamic acid on some pharmacokinetic parameters of L-dopa in the rat.
Topics: Animals; Biological Availability; Brain Chemistry; Dopamine; Drug Interactions; Glutamates; Homovanillic Acid; Kinetics; Levodopa; Male; Methyldopa; Motor Activity; Phenylpyruvic Acids; Rats | 1980 |
Concurrent determination of brain dopamine and 5-hydroxytryptamine turnovers in individual freely moving rats using repeated sampling of cerebrospinal fluid.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain; Dopamine; Homovanillic Acid; Hydroxyindoleacetic Acid; Male; Methyldopa; Probenecid; Rats; Rats, Inbred Strains; Serotonin | 1984 |
Effect of alpha-methyl fluorodopa on dopamine metabolites: importance of conjugation and egress.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Corpus Striatum; Dopamine; Homovanillic Acid; Hydroxyindoleacetic Acid; Male; Methyldopa; Probenecid; Rats; Rats, Inbred Strains | 1984 |
Cerebral decarboxylation of meta- and para-tyrosine.
Topics: Animals; Carboxy-Lyases; Corpus Striatum; Dose-Response Relationship, Drug; Homovanillic Acid; Male; Methyldopa; Mice; Tyramine; Tyrosine | 1983 |
Early L-dopa treatment initially retards but later enhances dopamine receptor supersensitivity following unilateral dopamine denervation.
Topics: Animals; Behavior, Animal; Denervation; Functional Laterality; Homovanillic Acid; Levodopa; Male; Methyldopa; Rats; Rats, Sprague-Dawley; Receptors, Dopamine; Rotation; Time Factors | 1994 |
Circadian phase dependent pharmacokinetics of L-dopa, its main metabolites (3-OMD, HVA, DOPAC) and carbidopa in rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Analysis of Variance; Animals; Area Under Curve; Carbidopa; Circadian Rhythm; Half-Life; Homovanillic Acid; Levodopa; Male; Methyldopa; Rats; Rats, Wistar | 1996 |
Brain catecholamine metabolism in catechol-O-methyltransferase (COMT)-deficient mice.
Topics: 3,4-Dihydroxyphenylacetic Acid; Anesthesia; Animals; Carbidopa; Catechol O-Methyltransferase; Corpus Striatum; Dopamine; Dopamine Agents; Female; Homovanillic Acid; Levodopa; Male; Methoxyhydroxyphenylglycol; Methyldopa; Mice; Mice, Inbred C57BL; Mice, Knockout; Microdialysis; Norepinephrine | 2002 |
Pharmacokinetic profile of methyldopa in the brain of sinaortic-denervated rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adrenergic alpha-Agonists; Animals; Brain; Brain Chemistry; Corpus Striatum; Denervation; Dopamine; Homovanillic Acid; Hypothalamus; Male; Methyldopa; Microdialysis; Pressoreceptors; Rats; Rats, Wistar | 2003 |
Circadian changes in CSF dopaminergic measures in restless legs syndrome.
Topics: Biopterins; Chronobiology Disorders; Dopamine; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male; Methyldopa; Middle Aged; Polysomnography; Restless Legs Syndrome | 2006 |
Circadian rhythms in RLS.
Topics: Biopterins; Chronobiology Disorders; Dopamine; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Methyldopa; Nocturnal Myoclonus Syndrome; Restless Legs Syndrome | 2006 |