methyldopa has been researched along with enalapril in 21 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (23.81) | 18.7374 |
| 1990's | 4 (19.05) | 18.2507 |
| 2000's | 5 (23.81) | 29.6817 |
| 2010's | 7 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Amidon, GL; Han, HK; Hsu, CP; Oh, DM; Rhie, JK; Saito, G; Stewart, BH | 1 |
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Campillo, NE; Guerra, A; Páez, JA | 1 |
| Avdeef, A; Tam, KY | 1 |
| Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K | 1 |
| Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V | 1 |
| Bellman, K; Knegtel, RM; Settimo, L | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Herlitz, H | 1 |
| Ambrosioni, E; Cinotti, G; Cuspidi, C; Leonetti, G; Malini, PL; Morabito, S; Pessina, A; Rappelli, A; Sampieri, L; Semplicini, A | 1 |
| Bhatnagar, D; Henkel, TW; Johnson, A; Thind, GS | 1 |
| Elghozi, JL; Meyer, P; Saad, MA | 1 |
| Ambrosioni, E; Magnani, B; Malini, PL; Strocchi, E | 1 |
| Kramsch, DM; Kulaga, SF; Walker, JF | 1 |
| Coull, A; Goodman, C; Rosendorff, C | 1 |
| Acevedo, E; Ebensperger, R; Gálvez, A; González-Jara, F; Jalil, JE; Lavandero, S; Meléndez, J; Pérez-Montes, V; Sapag-Hagar, M | 1 |
| Candy, G; Libhaber, E; Radevski, I; Sareli, P; Skudicky, D; Staessen, JA; Thijs, L; Tshele, E; Valtchanova, Z; Wang, JG | 1 |
| Ofor, OO | 1 |
2 review(s) available for methyldopa and enalapril
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
ACE-inhibitors and quality of life.
Topics: Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Atenolol; Captopril; Enalapril; Health Status; Humans; Hypertension; Methyldopa; Middle Aged; Oxprenolol; Quality of Life | 1990 |
5 trial(s) available for methyldopa and enalapril
| Article | Year |
|---|---|
Evaluation of the efficacy and safety of enalapril plus hydrochlorothiazide plus methyldopa vs standard triple therapy in the treatment of moderate to severe hypertension: results from a multicentre study.
Topics: Blood Pressure; Double-Blind Method; Drug Evaluation; Drug Therapy, Combination; Enalapril; Female; Heart Rate; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Male; Methyldopa; Middle Aged; Multicenter Studies as Topic; Propranolol; Randomized Controlled Trials as Topic | 1990 |
A parallel study of enalapril and captopril and 1 year of experience with enalapril treatment in moderate-to-severe essential hypertension.
Topics: Blood Pressure; Captopril; Clinical Trials as Topic; Dipeptides; Double-Blind Method; Enalapril; Female; Humans; Hypertension; Male; Methyldopa; Middle Aged; Proline; Pulse; Random Allocation | 1985 |
Long-term antihypertensive, metabolic and cellular effects of enalapril.
Topics: Adult; Blood Pressure; Double-Blind Method; Drug Evaluation; Drug Therapy, Combination; Enalapril; Erythrocyte Membrane; Humans; Hydrochlorothiazide; Hypertension; Methyldopa; Middle Aged; Sodium; Sodium-Potassium-Exchanging ATPase; Uric Acid | 1984 |
The efficacy and safety of enalapril in moderate to severe essential hypertension.
Topics: Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Captopril; Clinical Trials as Topic; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Enalapril; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Methyldopa; Middle Aged; Random Allocation; Statistics as Topic | 1984 |
Relationship between treatment-induced changes in left ventricular mass and blood pressure in black african hypertensive patients: results of the Baragwanath Trial.
Topics: Angiotensin-Converting Enzyme Inhibitors; Black People; Blood Pressure; Body Mass Index; Calcium Channel Blockers; Diastole; Diuretics; Echocardiography; Enalapril; Female; Humans; Hydrochlorothiazide; Hypertension; Hypertrophy, Left Ventricular; Male; Methyldopa; Middle Aged; Nifedipine; Patient Compliance; Regression Analysis; South Africa; Systole; Verapamil | 2002 |
14 other study(ies) available for methyldopa and enalapril
| Article | Year |
|---|---|
CHO/hPEPT1 cells overexpressing the human peptide transporter (hPEPT1) as an alternative in vitro model for peptidomimetic drugs.
Topics: Animals; Biological Transport; Caco-2 Cells; Carrier Proteins; CHO Cells; Cricetinae; Dipeptides; Humans; Kinetics; Peptide Transporter 1; Reproducibility of Results; Symporters; Transfection | 1999 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship | 2008 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical | 2010 |
How well can the Caco-2/Madin-Darby canine kidney models predict effective human jejunal permeability?
Topics: Animals; Disease Models, Animal; Dogs; Humans; Jejunal Diseases; Kidney Diseases; Models, Biological; Permeability; Porosity; Regression Analysis | 2010 |
QSAR-based permeability model for drug-like compounds.
Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2011 |
FDA-approved drug labeling for the study of drug-induced liver injury.
Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration | 2011 |
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation | 2014 |
Baroreflex sensitivity alteration following transient hemispheric ischaemia in rats: protective effect of alphamethyldopa and guanfacine.
Topics: Animals; Blood Pressure; Enalapril; Guanfacine; Guanidines; Heart Rate; Ischemic Attack, Transient; Labetalol; Male; Methyldopa; Nicardipine; Phenylacetates; Pressoreceptors; Rats; Rats, Inbred Strains; Reflex; Tachycardia | 1986 |
Effect of antihypertensive therapy on left ventricular function and myocardial perfusion at rest and during exercise.
Topics: Adult; Aged; Antihypertensive Agents; Blood Pressure; Coronary Circulation; Enalapril; Female; Heart; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Male; Methyldopa; Middle Aged; Physical Exertion; Propranolol; Random Allocation; Stroke Volume | 1984 |
Effects of antihypertensive treatment on cardiac IGF-1 during prevention of ventricular hypertrophy in the rat.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Enalapril; Heart; Hypertrophy, Left Ventricular; Insulin-Like Growth Factor I; Losartan; Male; Methyldopa; Myocardium; Propranolol; Radioimmunoassay; Rats; Rats, Sprague-Dawley | 1999 |
Oral enalapril-hydrochlorothiazide-methyldopa as first line treatment for severe hypertension in Nigerians.
Topics: Acute Disease; Administration, Oral; Adult; Aged; Antihypertensive Agents; Drug Therapy, Combination; Enalapril; Humans; Hydrochlorothiazide; Hypertension; Methyldopa; Middle Aged; Nigeria; Prospective Studies; Treatment Outcome | 2004 |