Page last updated: 2024-08-23

methyldopa and digoxin

methyldopa has been researched along with digoxin in 36 studies

Research

Studies (36)

Timeframe	Studies, this research(%)	All Research%
pre-1990	18 (50.00)	18.7374
1990's	1 (2.78)	18.2507
2000's	6 (16.67)	29.6817
2010's	11 (30.56)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Lombardo, F; Obach, RS; Waters, NJ	1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM	1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM	1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV	1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ	1
Avdeef, A; Tam, KY	1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ	1
Ekins, S; Williams, AJ; Xu, JJ	1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K	1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V	1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY	1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Fishel, B; Herzberg, M; Wiener, MH	1
Falase, AO	1
Markenson, JA; Sherman, RL	1
Kennedy, RD	1
Levine, L	1
Grille, W; Johnsen, K; Kolenda, KD	1
Cohen, P; McGrath, P; Newman, R; Spector, R; Uretsky, N	1
Lees, KR; Rubin, PC	1
Hunt, D; Peter, T; Sloman, G; Vohra, J	1
Amsterdam, EA; Mason, DT; Vismara, LA	1
Haft, JI; Kranz, PD; Shahabadi, AE; Venkatachalapathy, D	1
Gunnar, RM; Loeb, HS; Rahimtoola, SH; Rosen, KM; Sinno, MZ	1
Dietmann, K	1
Lamont, NM; Posel, K	1
Hancock, EW	1
Jain, A; Nicolle, FI; Sanders, CV	1
Bigger, JT; Davis, JC; Reiffel, JA	1
Love, EJ; Patten, SB	1
FRANK, MJ; LASKER, N; LEVINSON, GE; PACIFICO, AD	1
Hirai, S	1

Reviews

4 review(s) available for methyldopa and digoxin

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
Drug therapy for cardiovascular disease in the aged. Journal of the American Geriatrics Society, 1975, Volume: 23, Issue:3 Topics: Adrenergic beta-Antagonists; Aged; Anti-Bacterial Agents; Arrhythmias, Cardiac; Benzothiadiazines; Cardiac Rehabilitation; Cardiac Surgical Procedures; Cardiovascular Diseases; Coronary Disease; Delayed-Action Preparations; Digoxin; Diuretics; Endocarditis; Female; Heart Failure; Humans; Hypertension; Hypertension, Malignant; Hyperthyroidism; Hypothyroidism; Isosorbide Dinitrate; Male; Methyldopa; Middle Aged; Nitroglycerin; Sodium Chloride Symporter Inhibitors	1975
Reported ocular side effects of the ten most frequently prescribed drugs. Journal of the American Optometric Association, 1979, Volume: 50, Issue:2 Topics: Acetaminophen; Ampicillin; Brompheniramine; Codeine; Diazepam; Digoxin; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Eye; Eye Diseases; Female; Furosemide; Humans; Hydrochlorothiazide; Methyldopa; Phenylephrine; Phenylpropanolamine; Pregnancy; Propranolol; Tetracyclines; Triamterene	1979
[Dementia induced by cardiokinetic and anti-hypertensive drugs]. Nihon rinsho. Japanese journal of clinical medicine, 2004, Volume: 62 Suppl Topics: Antihypertensive Agents; Cardiotonic Agents; Clonidine; Dementia; Digitoxin; Digoxin; Half-Life; Humans; Methyldopa; Propranolol; Reserpine	2004

Trials

2 trial(s) available for methyldopa and digoxin

Article	Year
Does intervention by a nurse improve medication compliance? Archives of internal medicine, 1978, Volume: 138, Issue:1 Topics: Aged; Digoxin; Drug Therapy; Evaluation Studies as Topic; Female; Humans; Male; Methyldopa; Middle Aged; Nurse Practitioners; Patient Compliance	1978
Disopyramide phosphate: clinical efficacy of a new oral antiarrhythmic drug. Clinical pharmacology and therapeutics, 1974, Volume: 16, Issue:2 Topics: Adult; Aged; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Benzothiadiazines; Digoxin; Disopyramide; Diuretics; Electrocardiography; Female; Humans; Male; Methyldopa; Middle Aged; Placebos; Potassium Chloride; Pyridines; Sodium Chloride Symporter Inhibitors; Tachycardia	1974

Article

Year

Does intervention by a nurse improve medication compliance?

Archives of internal medicine, 1978, Volume: 138, Issue:1

Topics: Aged; Digoxin; Drug Therapy; Evaluation Studies as Topic; Female; Humans; Male; Methyldopa; Middle Aged; Nurse Practitioners; Patient Compliance

1978

Disopyramide phosphate: clinical efficacy of a new oral antiarrhythmic drug.

Clinical pharmacology and therapeutics, 1974, Volume: 16, Issue:2

Topics: Adult; Aged; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Benzothiadiazines; Digoxin; Disopyramide; Diuretics; Electrocardiography; Female; Humans; Male; Methyldopa; Middle Aged; Placebos; Potassium Chloride; Pyridines; Sodium Chloride Symporter Inhibitors; Tachycardia

1974

Other Studies

30 other study(ies) available for methyldopa and digoxin

Article	Year
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1. Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19 Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship	2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors. Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21 Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship	2008
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models. Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3 Topics:	2008
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination. Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3 Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations	2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species. Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6 Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics	2010
How well can the Caco-2/Madin-Darby canine kidney models predict effective human jejunal permeability? Journal of medicinal chemistry, 2010, May-13, Volume: 53, Issue:9 Topics: Animals; Disease Models, Animal; Dogs; Humans; Jejunal Diseases; Kidney Diseases; Models, Biological; Permeability; Porosity; Regression Analysis	2010
Developing structure-activity relationships for the prediction of hepatotoxicity. Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes	2010
A predictive ligand-based Bayesian model for human drug-induced liver injury. Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12 Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands	2010
QSAR-based permeability model for drug-like compounds. Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8 Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship	2011
FDA-approved drug labeling for the study of drug-induced liver injury. Drug discovery today, 2011, Volume: 16, Issue:15-16 Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration	2011
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds. Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10 Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding	2012
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification. Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship	2012
Hepatic microsomal enzyme induction and its evaluation in a clinical laboratory. Israel journal of medical sciences, 1977, Volume: 13, Issue:5 Topics: Adult; Aged; Diazepam; Digoxin; Enzyme Induction; Female; Furosemide; gamma-Glutamyltransferase; Glucaric Acid; Humans; Male; Methyldopa; Microsomes, Liver; Middle Aged; Quinidine	1977
Cardiomegaly of unknown origin among Nigerian adults: role of hypertension in its aetiology. British heart journal, 1977, Volume: 39, Issue:6 Topics: Adolescent; Adult; Aged; Alcoholic Beverages; Benzothiadiazines; Blood Pressure; Cardiomegaly; Cardiomyopathies; Child; Diet; Digoxin; Diuretics; Female; Furosemide; Heart Failure; Humans; Hypertension; Male; Methyldopa; Middle Aged; Nigeria; Sodium Chloride Symporter Inhibitors	1977
Renal involvement in progressive systemic sclerosis: prolonged survival with aggressive antihypertensive management. Arthritis and rheumatism, 1979, Volume: 22, Issue:10 Topics: Adult; Antihypertensive Agents; Cardiomegaly; Digoxin; Drug Therapy, Combination; Female; Furosemide; Humans; Hydralazine; Hypertension, Malignant; Hypertension, Renal; Kidney Diseases; Methyldopa; Minoxidil; Propranolol; Scleroderma, Systemic; Time Factors	1979
[Drug interaction during therapy with tolbutamide. The influence of some commonly used drugs on plasma level and half life in diabetic out-patients (author's transl)]. Medizinische Klinik, 1979, Dec-14, Volume: 74, Issue:50 Topics: Buformin; Diabetes Mellitus; Digoxin; Drug Interactions; Enzyme Inhibitors; Half-Life; Humans; Methyldopa; Phenprocoumon; Tolbutamide	1979
Treatment of cardiovascular diseases. British medical journal (Clinical research ed.), 1987, Feb-07, Volume: 294, Issue:6568 Topics: Adrenergic beta-Antagonists; Anti-Arrhythmia Agents; Antihypertensive Agents; Digoxin; Female; Humans; Lidocaine; Methyldopa; Pregnancy; Pregnancy Complications, Cardiovascular; Quinidine	1987
Verapamil induced premature ventricular beats before reversion of supraventricular tachycardia. British heart journal, 1974, Volume: 36, Issue:12 Topics: Adolescent; Adult; Aged; Arrhythmias, Cardiac; Blood Pressure; Bradycardia; Digoxin; Electrocardiography; Female; Heart Ventricles; Humans; Injections, Intravenous; Male; Methyldopa; Middle Aged; Syndrome; Tachycardia; Tachycardia, Paroxysmal; Verapamil; Wolff-Parkinson-White Syndrome	1974
Orally administered methyldopa. Hemodynamic effects in the presence and absence of congestive heart failure. Archives of internal medicine, 1974, Volume: 134, Issue:3 Topics: Administration, Oral; Adult; Aged; Blood Pressure; Cardiac Output; Digoxin; Heart Failure; Heart Rate; Hemodynamics; Humans; Hypertension; Methyldopa; Middle Aged	1974
Cardiac conduction in patients with symptomatic sinus node disease. Circulation, 1971, Volume: 43, Issue:6 Topics: Aged; Arrhythmia, Sinus; Atropine; Bundle-Branch Block; Digoxin; Electrocardiography; Female; Heart Block; Heart Conduction System; Heart Rate; Humans; Male; Methyldopa; Middle Aged; Pacemaker, Artificial; Sinoatrial Node	1971
[Promotion of organ circulation by raubasine]. Arzneimittel-Forschung, 1967, Volume: 17, Issue:8 Topics: Animals; Arteries; Blood Circulation; Blood Flow Velocity; Blood Pressure; Blood Volume; Cardiac Output; Coronary Vessels; Digoxin; Dogs; Guinea Pigs; Heart Rate; Methyldopa; Myocardium; Oxygen Consumption; Rats; Reserpine; Strophanthins; Vascular Resistance; Vasodilator Agents; Veins; Yohimbine	1967
The coronary attack: concepts on its etiology and hemodynamic management. American heart journal, 1969, Volume: 78, Issue:4 Topics: Aged; Arrhythmias, Cardiac; Aspartate Aminotransferases; Biophysical Phenomena; Biophysics; Blood Flow Velocity; Blood Pressure; Cardiac Output; Coronary Disease; Digoxin; Electrocardiography; Heart; Heart Failure; Humans; Hydrocortisone; Hypotension; Isoproterenol; Lidocaine; Male; Methyldopa; Middle Aged; Models, Biological; Propranolol; Stress, Psychological; Veins	1969
Bigeminal rhythm on multiple cardiac drug therapy. Hospital practice (Office ed.), 1984, Volume: 19, Issue:2 Topics: Arrhythmias, Cardiac; Cardiovascular Agents; Digoxin; Drug Therapy, Combination; Electrocardiography; Furosemide; Humans; Hydrochlorothiazide; Male; Methyldopa; Middle Aged; Nitroglycerin; Potassium Chloride; Quinidine	1984
Drug fever during treatment of pulmonary edema. Southern medical journal, 1982, Volume: 75, Issue:9 Topics: Aminophylline; Blood Pressure; Digoxin; Fever; Furosemide; Humans; Hydralazine; Male; Methyldopa; Middle Aged; Pulmonary Edema	1982
Sinus node dysfunction caused by methyldopa and digoxin. JAMA, 1981, Mar-27, Volume: 245, Issue:12 Topics: Aged; Digoxin; Drug Synergism; Female; Heart Failure; Heart Ventricles; Humans; Hypertension; Methyldopa; Sick Sinus Syndrome	1981
Neuropsychiatric adverse drug reactions: passive reports to Health and Welfare Canada's adverse drug reaction database (1965-present). International journal of psychiatry in medicine, 1994, Volume: 24, Issue:1 Topics: Adverse Drug Reaction Reporting Systems; Benzodiazepines; Canada; Databases, Factual; Delirium; Digoxin; Hallucinations; Histamine Agonists; Humans; Methyldopa; Mood Disorders; Substance-Related Disorders	1994
CARDIOVASCULAR FUNCTION IN PERITONEAL DIALYSIS. Transactions - American Society for Artificial Internal Organs, 1965, Volume: 11 Topics: Anemia; Blood Pressure; Blood Pressure Determination; Blood Urea Nitrogen; Blood Volume; Cardiac Catheterization; Cardiac Output; Cardiovascular System; Dialysis; Digoxin; Drug Therapy; Glomerulonephritis; Guanethidine; Humans; Methyldopa; Peritoneal Dialysis; Pyelonephritis; Renal Dialysis; Urine	1965