Page last updated: 2024-08-23

methyldopa and cocaine

methyldopa has been researched along with cocaine in 21 studies

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-199017 (80.95)18.7374
1990's0 (0.00)18.2507
2000's2 (9.52)29.6817
2010's2 (9.52)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lombardo, F; Obach, RS; Waters, NJ1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Bellman, K; Knegtel, RM; Settimo, L1
van Zwieten, PA1
Luchins, D1
Heise, A; Kroneberg, G1
Güther, W; Schümann, HJ1
Gershon, S; Wallach, MB2
Stock, K; Westermann, E1
Bhargava, KP; Jaju, BP; Tangri, KK1
McGill, JS; Pruss, TP1
Afrikanov, II; Vedernikov, YP1
Aihara, H; Kasai, A; Sakai, T1
Baldessarini, RJ; Karobath, M1
Araki, H1
Ehinger, B; Falck, B1
Gulati, OD; Parikh, HM; Ringe, SY; Sherlekar, ML1
Smith, CB2

Other Studies

21 other study(ies) available for methyldopa and cocaine

ArticleYear
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
    Pharmaceutical research, 2014, Volume: 31, Issue:4

    Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation

2014
Interaction between centrally acting hypotensive drugs and tricyclic antidepressants.
    Archives internationales de pharmacodynamie et de therapie, 1975, Volume: 214, Issue:1

    Topics: Amphetamine; Animals; Antidepressive Agents, Tricyclic; Antihypertensive Agents; Benzimidazoles; Blood Pressure; Cats; Clonidine; Cocaine; Desipramine; Dioxanes; Drug Interactions; Ephedrine; Female; Male; Methyldopa; Piperidines; Reserpine

1975
The dopamine hypothesis of schizophrenia. A critical analysis.
    Neuropsychobiology, 1975, Volume: 1, Issue:6

    Topics: Acetylcholine; Amphetamine; Apomorphine; Cocaine; Dopamine; Electroconvulsive Therapy; gamma-Aminobutyric Acid; Humans; Levodopa; Methyldopa; Methyltyrosines; Models, Neurological; Psychoses, Substance-Induced; Schizophrenia; Tranquilizing Agents

1975
Central nervous alpha-adrenergic receptors and the mode of action of alpha-methyldopa.
    Naunyn-Schmiedeberg's archives of pharmacology, 1973, Volume: 279, Issue:3

    Topics: Adrenergic alpha-Antagonists; Angiotensin II; Animals; Aorta; Blood Pressure; Catecholamines; Cats; Cerebral Ventricles; Cocaine; Dopamine; Dose-Response Relationship, Drug; Drug Interactions; Hypotension; Isoproterenol; Methyldopa; Norepinephrine; Perfusion; Phentolamine; Propranolol; Rats; Receptors, Adrenergic; Reserpine; Tyramine; Yohimbine

1973
[Studies on the mechanism of action of angiotensin on the isolated aorta preparation and on the blood pressure of rats and guinea pigs].
    Naunyn-Schmiedebergs Archiv fur experimentelle Pathologie und Pharmakologie, 1967, Volume: 256, Issue:2

    Topics: Angiotensin II; Animals; Aorta; Blood Pressure; Cocaine; Guinea Pigs; In Vitro Techniques; Male; Methyldopa; Muscle, Smooth; Normetanephrine; Phentolamine; Rats; Reserpine; Tyramine

1967
A neuropsychopharmacological comparison of d-amphetamine, L-dopa and cocaine.
    Neuropharmacology, 1971, Volume: 10, Issue:6

    Topics: Animals; Behavior, Animal; Cats; Cocaine; Cortical Synchronization; Dextroamphetamine; Dihydroxyphenylalanine; Electroencephalography; Female; Hair; Humans; Hydrazines; Male; Methyldopa; Paranoid Disorders; Parkinson Disease; Phenethylamines; Reticular Formation; Salivation; Sleep, REM; Stereoisomerism

1971
[On the significance of the noradrenaline content of fatty tissue for the mobilization of unesterified fatty acids].
    Naunyn-Schmiedebergs Archiv fur experimentelle Pathologie und Pharmakologie, 1965, Sep-27, Volume: 251, Issue:5

    Topics: Adipose Tissue; Adrenal Medulla; Animals; Cocaine; Cold Temperature; Enzymes; Epididymis; Epinephrine; Fatty Acids; In Vitro Techniques; Lipids; Male; Metaraminol; Methyldopa; Methyltyrosines; Nialamide; Norepinephrine; Normetanephrine; Octopamine; Pargyline; Rats; Reserpine; Transaminases; Tyramine; Tyrosine; Tyrosine Transaminase

1965
Mechanism of the central hypotensive action of guanethidine.
    British journal of pharmacology and chemotherapy, 1966, Volume: 27, Issue:3

    Topics: Animals; Brain; Cerebral Ventricles; Cocaine; Dogs; Ethanolamines; Guanethidine; Injections; Methyldopa; Norepinephrine; Phenoxybenzamine; Reserpine; Tetrabenazine; Tranylcypromine; Vasomotor System

1966
The effect of various agents on the pressor response to dopa in the anesthetized dog.
    European journal of pharmacology, 1969, Volume: 8, Issue:1

    Topics: Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Arteries; Blood Pressure; Bretylium Compounds; Cocaine; Cresols; Dihydroxyphenylalanine; Dogs; Dopamine Antagonists; Female; Guanethidine; Hydrazines; Male; Methyldopa; Norepinephrine; Oxidoreductases; Stimulation, Chemical; Thiocarbamates

1969
On the role of a central adrenergic mechanism in morphine analgesic action.
    The Journal of pharmacy and pharmacology, 1969, Volume: 21, Issue:12

    Topics: Amphetamine; Animals; Brain; Cocaine; Disulfiram; Drug Synergism; Female; Iproniazid; Methyldopa; Morphine; Norepinephrine; Pyrogallol; Rats; Reserpine; Tryptophan

1969
The effect of dopamine on peripheral vasculature of the rat.
    Japanese journal of pharmacology, 1972, Volume: 22, Issue:5

    Topics: Animals; Blood Pressure; Blood Vessels; Cocaine; Constriction; Depression, Chemical; Disulfiram; Dopamine; Dopamine Antagonists; Drug Synergism; Ephedrine; Ergotamine; Haloperidol; Hindlimb; Kidney; Male; Methyldopa; Morphine; Norepinephrine; Perfusion; Propranolol; Rats; Reserpine; Stimulation, Chemical; Tyramine

1972
Effects of L-DOPA and L-3-O-methyl-DOPA on uptake of (3H)L-methionine by synaptosomes.
    Neuropharmacology, 1972, Volume: 11, Issue:5

    Topics: Animals; Binding, Competitive; Biological Transport, Active; Brain; Centrifugation; Cocaine; Depression, Chemical; Desipramine; Dihydroxyphenylalanine; Dinitrophenols; In Vitro Techniques; Kinetics; Male; Methionine; Methyldopa; Mitochondria; Nerve Endings; Ouabain; Rats; Sodium; Synaptosomes; Temperature; Time Factors; Tritium

1972
[The mechanism of relaxation produced by periarterial nerve stimulation, nicotine and tyramine in the isolated rabbit ileum, particularly in relation to acetylcholine and calcium].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1972, Volume: 68, Issue:4

    Topics: Acetylcholine; Animals; Bretylium Compounds; Calcium; Cocaine; Depression, Chemical; Dibenzylchlorethamine; Electric Stimulation; Epinephrine; Female; Guanethidine; Hemicholinium 3; Hexamethonium Compounds; Ileum; In Vitro Techniques; Intestine, Small; Male; Methyldopa; Muscle Contraction; Muscle, Smooth; Nicotine; Norepinephrine; Propranolol; Rabbits; Tachyphylaxis; Tyramine

1972
Cellular uptake of some amino acids and amines in vitro into rabbit and monkey anterior eye segment preparations.
    Experimental eye research, 1970, Volume: 10, Issue:2

    Topics: 5-Hydroxytryptophan; Amino Acids; Animals; Biological Transport, Active; Capillaries; Ciliary Body; Cocaine; Desipramine; Dihydroxyphenylalanine; Dopamine; Epithelium; Formaldehyde; Haplorhini; In Vitro Techniques; Iris; Melanocytes; Methyldopa; Methyltyrosines; Microscopy, Fluorescence; Norepinephrine; Normetanephrine; Ouabain; Pilocarpine; Quaternary Ammonium Compounds; Rabbits

1970
The induction and antagonism of central nervous system stimulant-induced stereotyped behavior in the cat.
    European journal of pharmacology, 1972, Volume: 18, Issue:1

    Topics: Amphetamine; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Behavior, Animal; Benzyl Compounds; Cats; Central Nervous System; Cocaine; Dextroamphetamine; Dihydroxyphenylalanine; Drug Antagonism; Hydrazines; Methyldopa; Methylphenidate; Methyltyrosines; Pemoline; Reserpine; Serine; Stimulation, Chemical

1972
An investigation of alpha-methyl amino-acids and their derivatives on isolated tissue preparations.
    British journal of pharmacology, 1970, Volume: 40, Issue:4

    Topics: Amino Acids; Animals; Cocaine; Disulfiram; Dopamine; Ear, External; Heart; Ileum; In Vitro Techniques; Metaraminol; Methyldopa; Methyltyrosines; Normetanephrine; Perfusion; Rabbits; Rats; Reserpine; Sodium; Tyramine

1970
The role of monoamine oxidase in the intraneuronal metabolism of norepinephrine released by indirectly-acting sympathomimetic amines or by adrenergic nerve stimulation.
    The Journal of pharmacology and experimental therapeutics, 1966, Volume: 151, Issue:2

    Topics: Animals; Cocaine; Dextroamphetamine; Female; Guinea Pigs; Heart Atria; In Vitro Techniques; Male; Mephentermine; Methyldopa; Monoamine Oxidase; Neurons; Norepinephrine; Pargyline; Sympathetic Nervous System; Sympathomimetics; Tritium; Tyramine; Urine

1966
ENHANCEMENT BY RESERPINE AND ALPHA-METHYL DOPA OF THE EFFECTS OF D-AMPHETAMINE UPON THE LOCOMOTOR ACTIVITY OF MICE.
    The Journal of pharmacology and experimental therapeutics, 1963, Volume: 142

    Topics: Antihypertensive Agents; Brain; Cocaine; Dextroamphetamine; Dihydroxyphenylalanine; Dopamine; Locomotion; Methyldopa; Mice; Motor Activity; Pharmacology; Piperidines; Research; Reserpine; Serotonin

1963