methyldimethylaminoazobenzene and p-dimethylaminoazobenzene
methyldimethylaminoazobenzene has been researched along with p-dimethylaminoazobenzene in 175 studies
Research
Studies (175)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 168 (96.00) | 18.7374 |
| 1990's | 6 (3.43) | 18.2507 |
| 2000's | 1 (0.57) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Kitagawa, Y; Kuroiwa, Y | 3 |
| Fiala, AE; Fiala, S; Kettering, WG; Mohindru, A; Morris, HP | 1 |
| Labuc, GE; Madsen, NP | 1 |
| Fiala, S; Pragani, B; Reuber, MD | 1 |
| Boss, JH; Okon, E; Rosenmann, E; Zajicek, G | 1 |
| Baumler, A; Carruthers, C; Neilson, A | 2 |
| Baumler, A; Carruthers, C; Lin, JK | 1 |
| Dolezalová, V; Nĕmecek, R; Simícková, M; Stratil, P | 1 |
| Emerson, RL; Smith, LD | 1 |
| Dempo, K; Enomoto, K; Mori, M; Onoé, T | 1 |
| Kitagawa, T; Miller, EC; Miller, JA; Pitot, HC | 1 |
| Flaks, A; Flaks, B | 2 |
| Hori, T; Mori, Y; Toyoshi, K | 1 |
| Aberlin, ME; Litman, GW | 1 |
| Egashira, T; Kuroiwa, Y; Uchida, A | 1 |
| Blunck, JM; Labuc, GE | 3 |
| Folse, DS; Holoubek, V; Patel, NT | 1 |
| Kojima, S; Kubodera, A; Odate, M; Yamamoto, M | 1 |
| Kitagawa, T; Sugano, H | 1 |
| Fukuda, M; Katayama, S; Nakano, Y; Yamaguchi, I | 1 |
| Akao, M; Kuroda, K | 2 |
| Christoffersen, T | 1 |
| Baumler, A; Carruthers, C; Neilson, A; Pressman, D | 1 |
| Ichikawa, M; Ichikawa, Y; Ishigami, S; Yamano, T | 1 |
| Dempo, K; Kaneko, A; Onoé, T; Yokoyama, S; Yoshida, Y | 1 |
| Lambooy, JP | 1 |
| Frenkel, JK; Reddy, JK | 1 |
| Buschmann, RJ; Chomet, B; Reddy, KP | 1 |
| Griffin, AC; Jacobs, MM | 1 |
| Holoubek, V; Patel, NT | 3 |
| Chisaka, N; Kaneko, A; Onoé, T; Yoshida, Y | 1 |
| Boyd, H; Hensley, GT | 1 |
| Boyd, H; McAfee, DA; Rubin, JJ | 1 |
| Arcos, JC; Argus, MF; Bryant, GM | 1 |
| Boyd, H; Martin, TJ | 1 |
| Mainigi, KD; Sorof, S | 1 |
| Bismuth, H; Decloître, F; Franco, D; Morin, J; Ricco, JB | 1 |
| Brown, CA; Evarts, RP | 1 |
| Blunck, JM; Crowther, CE | 1 |
| Block, JA; Roy, RM | 1 |
| Flaks, B; Nicoll, JW | 1 |
| Flaks, B; Teh, EC | 1 |
| Holoubek, V; Yoshida, M | 1 |
| Daoud, AH; Griffin, AC | 2 |
| Kanematsu, T | 1 |
| Glover, EL; Reuber, MD | 1 |
| Baba, S; Mori, Y; Tyoshi, K | 1 |
| Baba, S; Mori, Y; Toyoshi, K | 1 |
| Endo, Y; Hirai, H; Kasahara, N; Kawachi, Y; Kudo, H; Kuwa, K; Sakamoto, S; Sunaga, T; Taga, H; Uchikoshi, T | 1 |
| Chiu, JF; Dong, JM; Fukuda, K; Kilianska, Z | 1 |
| Fujimaki, M; Hirota, S; Karaki, Y; Munakata, S; Saeki, T | 1 |
| Mack, DO; Reed, VL; Smith, LD | 1 |
| Bybee, A; Kelly, MD; Pritchard, NR; Styles, JA | 1 |
| Kelly, MD; Pritchard, NR; Styles, JA | 1 |
| Chen, RM; Chen, ZQ; Chu, TH; Ge, YP; Li, WY; Wan, ZY; Yeh, HJ | 1 |
| Antoniades, D; Holoubek, V | 1 |
| Arcus, M; Douglas, A; Porter, I; Yeoh, G | 1 |
| Chakraborty, S; Dunsford, HA; Hunt, JM; Scott, RJ; Sell, S | 1 |
| Flaks, B; Winton, DJ | 2 |
| Hiasa, Y; Kamiya, T; Yamashita, M; Yanagi, S | 1 |
| Nishikawa, S | 1 |
| Higashi, K; Higashi, T; Kano, S; Kido, Y; Mori, T; Sakamoto, Y; Tateishi, N; Yano, M | 1 |
| Adamson, RH | 1 |
| Handa, Y; Miyazaki, M; Sato, J | 2 |
| Hirose, K; Hirose, M; Hosoda, K; Ito, N; Shirai, T | 1 |
| Fukui, R; Higashi, T; Sakamoto, Y; Sekiyama, M; Tateishi, N; Yoshimoto, F | 1 |
| Handa, Y; Miyazaki, M; Sato, J; Suzuki, Y | 1 |
| Kurup, CK; Saikumar, P | 3 |
| Kittler, JM; Meisler, NT; Thanassi, JW | 1 |
| Degawa, M; Hashimoto, Y; Hishinuma, T; Sato, J; Tokiwa, T | 1 |
| Kahn, A; Lamas, E; Schweighoffer, F | 1 |
| Guillouzo, A; Kahn, A; Lamas, E | 1 |
| Kamiya, T; Konishi, Y; Sakamoto, M; Shibata, K; Takahashi, S; Tsutsumi, M; Yanagi, S | 1 |
| Iwata, H; Kuniyasu, T; Mori, H; Mori, Y; Ni-i, H; Nishiwaki, A; Sugie, S; Tanaka, T | 1 |
| Aitken, A; Beale, D; Coles, B; Kadlubar, F; Ketterer, B; Lay, J; Miller, D | 1 |
| Ahn, YH; Chai, KJ; Kim, SN; Kim, YS | 1 |
| Flaks, A; Flaks, B; Winton, DJ | 1 |
| Crowne, HM; Medvedev, ZA; Medvedeva, MN | 1 |
| Ashby, J; Elliott, BM; Hart, D; Lefevre, PA; Pritchard, N; Robinson, M; Styles, J | 1 |
| Higashi, T; Masuda, S; Nishii, T; Sakamoto, Y; Takamisawa, I; Tateishi, N; Yoshimoto, F | 1 |
| Sugimoto, T; Terayama, H | 1 |
| Horng, SC; Lin, JK; Tung, TC | 1 |
| Kawada, K; Koda, A; Konishi, Y; Mori, Y; Nagai, H; Niwa, T; Ojima, A; Toyoshi, K | 1 |
| Holoubek, V; Ramagli, LS | 1 |
| Fiala, AE; Fiala, S; Ostrander, H; Trout, EC | 1 |
| Yeoh, GC | 1 |
| Matsuura, K; Miyano, K; Miyazaki, M; Nakabayashi, H; Sato, J; Tsunashima, M; Wahid, S | 1 |
| Cake, M; Godfrey, M; Toia, R; Yeoh, G | 1 |
| Wahid, S | 1 |
| Miyano, K; Miyazaki, M; Sato, J; Wahid, S; Yabe, T | 1 |
| Adler, B; Godfrey, ML; Toia, RF; Yeoh, GC | 1 |
| Ingleton, PM; Varey, SN | 1 |
| Kanai, K; Oda, T; Oka, H; Torii, M; Watabe, H | 1 |
| Nishiyama, S; Sato, J; Tokiwa, T; Yoshimoto, J | 1 |
| Briggs, RC; Gronert, BJ; Hnilica, LS; Page, DL; Schmidt, WN | 2 |
| Chiu, JF; Gabryelak, T; Schwartz, CE; Smith, CJ; Taylor, JM | 1 |
| Blunck, JM; Smith, ML; Vorrath, EM | 1 |
| Gronert, BJ; Hnilica, LS; McKusick, KB; Page, DL; Schmidt, WN | 1 |
| French, BT; Hanausek-Walaszek, M; Schumm, DE; Walaszek, Z; Webb, TE | 1 |
| Hagiwara, A; Hasegawa, R; Ito, N; Shirai, T; Tatematsu, M; Tsuda, H | 1 |
| Fujii, K | 1 |
| Nishiyama, S; Sato, J; Tanaka, T; Tokiwa, T | 1 |
| Bhargava, MM; Levine, WG; Samuels, AR | 1 |
| Flaks, A; Flaks, B; Jones, H; Milsom, A | 1 |
| Akao, M; Kuroda, K; Terao, K | 1 |
| Mori, Y; Niwa, T; Toyoshi, K | 3 |
| Egashira, T; Yamamoto, T; Yamanaka, Y | 1 |
| Daoust, R | 1 |
| Kumar, PS; Kurup, CK | 1 |
| Elliott, BM | 1 |
| Ito, N; Koyama, Y; Nakajima, T; Sato, A; Shirai, T | 1 |
| Daimon, M; Ishikawa, K; Sato, J; Tsutsumi, K; Tsutsumi, R | 1 |
| Castonguay, A; Schut, HA | 1 |
| Hirano, K; Mori, Y; Ni-i, H; Niwa, T; Sugiura, M; Toyoshi, K; Yamazaki, H | 1 |
| Hino, O; Kitagawa, T | 1 |
| Berges, J; Boisnard-Rissel, M; Guillouzo, A; Le Provost, E; Schapira, F; Weber, A | 1 |
| Dolezalová, V; Nĕmecek, R; Simícková, M | 1 |
| Holoubek, V; Patel, NT; Yoshida, M | 1 |
| Arias, IM; Bhargava, M; Ohmi, N | 1 |
| Arias, IM; Bhargava, MM; Ohmi, N | 1 |
| Kitagawa, T; Natria, T; Watanabe, R | 1 |
| Hori, T; Kawada, K; Koda, A; Mori, Y; Nagai, H; Niwa, T; Ojima, A; Toyoshi, K | 1 |
| Ashby, J; Lefevre, PA | 1 |
| Egashira, T; Kuroiwa, Y; Yamamoto, T; Yamanaka, Y | 1 |
| Hino, O; Kitagawa, T; Kosugi, A; Nagao, M; Nemoto, N | 1 |
| Egashira, T; Kuroiwa, Y; Yamamoto, T | 1 |
| Igarashi, S; Kawajiri, K; Kimura, T; Kodama, M; Nagata, C; Tagashira, Y; Watanabe, J; Yonekawa, H | 1 |
| Kojima, S; Kubodera, A; Sasaki, T | 1 |
| Esumi, H; Makino, R; Nagase, S; Sato, S; Sugimura, T; Takahashi, Y | 1 |
| Flaks, A; Flaks, B; Milsom, A | 1 |
| Kimura, T; Kodama, M; Nagata, C | 1 |
| Sato, J; Tokiwa, T | 1 |
| Bussaka, Y; Kawasaki, H; Kikuchi, S; Kojiro, M; Moriguchi, Y; Morita, S; Nishi, F; Ohtake, H; Okinaga, T; Umezaki, N; Yano, K | 1 |
| Abelmoschi, ML; Balbi, C; Pala, M; Parodi, S; Russo, P; Santi, L; Taningher, M | 1 |
| Gopalakrishna, R; Nagarajan, B | 1 |
| SCHNEIDER, WC; SHELTON, E; STRIEBICH, MJ | 1 |
| HOGEBOOM, GH; SCHNEIDER, WC; SHELTON, E; STRIEBICH, MJ | 1 |
| BEYER, V; GRAFFI, A; SCHNEIDER, EJ | 1 |
| GELBOIN, HV; MILLER, EC; MILLER, JA | 1 |
| ARCOS, JC; GOSCH, HH; ZICKAFOOSE, D | 1 |
| SCHRAMM, T | 1 |
| ARCOS, JC; CUNNINGHAM, RW; GRIFFITH, GW | 1 |
| HAWTREY, AO; SCHIRREN, V | 1 |
| ODASHIMA, S | 1 |
| TAKAHASHI, G | 1 |
| HAWTREY, AO; NOURSE, LD | 1 |
| DIJKSTRA, J; HAWTREY, AO; NOURSE, L; SCHIRREN, V; SCHOEMAN, CA | 1 |
| HIROTA, T | 2 |
| HADJIOLOV, D | 1 |
| EDWARDS, CF; HEGGEN, GE; OLSON, KB; STEIN, AA | 1 |
| ISAKA, H; ODASHIMA, S; SATOH, H | 1 |
| BROWN, RR; PETASNICK, JP; PRICE, JM | 1 |
| KOZELKA, FL; PEDRERO, E | 1 |
| BAUMANN, CA; MILLER, WL; RUMSFELD, HW | 1 |
| HARMAN, JW; MILLER, EC; MILLER, JA; PRICE, JM | 1 |
| MILLER, EC; PRICE, JM | 1 |
| Bryzgalov, LO; Ilnitskaya, SI; Kaledin, VI; Kobzev, VF; Kropachev, KY; Levashova, ZB; Merkulova, TI; Pakharukova, MY; Timofeeva, OA; Vasiliev, GV | 1 |
Reviews
1 review(s) available for methyldimethylaminoazobenzene and p-dimethylaminoazobenzene
| Article | Year |
|---|---|
Metabolism of carcinogenic amino derivatives in various species and DNA alkylation by their metabolites.
Topics: 1-Naphthylamine; 2-Acetylaminofluorene; 2-Naphthylamine; Alkylation; Amines; Aminobiphenyl Compounds; Animals; Benzidines; Carcinogens; Cricetinae; Diethylnitrosamine; Dimethylnitrosamine; DNA; Guinea Pigs; Humans; Methyldimethylaminoazobenzene; Mice; Nicotiana; Nitrosamines; p-Dimethylaminoazobenzene; Plants, Toxic; Rats; Species Specificity | 1984 |
Other Studies
174 other study(ies) available for methyldimethylaminoazobenzene and p-dimethylaminoazobenzene
| Article | Year |
|---|---|
Change in intracellular pH of rat liver during azo-dye carcinogenesis.
Topics: Animals; Carcinoma, Hepatocellular; Dose-Response Relationship, Drug; Growth; Hydrogen-Ion Concentration; Liver; Liver Neoplasms; Male; Methyldimethylaminoazobenzene; Neoplasms, Experimental; p-Dimethylaminoazobenzene; Precancerous Conditions; Rats | 1976 |
Glutathione and gamma glutamyl transpeptidase in rat liver during chemical carcinogenesis.
Topics: 2-Acetylaminofluorene; Animals; Carcinoma, Hepatocellular; Chloramphenicol; gamma-Glutamyltransferase; Glutathione; Liver Neoplasms; Male; Methylcholanthrene; Methyldimethylaminoazobenzene; p-Dimethylaminoazobenzene; Puromycin; Rats | 1976 |
Inhibition by 3'-methyl-4-dimethylamino-azobenzene of in vitro cell-free protein synthesis: possible involvement of an electrophilic metabolite.
Topics: Aminopyrine N-Demethylase; Aniline Hydroxylase; Animals; Cell-Free System; Cysteine; Depression, Chemical; Glutathione; In Vitro Techniques; Leucine; Liver; Male; Methyldimethylaminoazobenzene; NADP; Oxidoreductases; p-Dimethylaminoazobenzene; Phenobarbital; Polyethylene Glycols; Protein Biosynthesis; Rats | 1977 |
Inhibition of 3'-methyl-4-dimethylaminoazobenezene-induced hepatocarcinogenesis by portacaval shunt.
Topics: Animals; Biotransformation; Carcinoma, Hepatocellular; gamma-Glutamyltransferase; Glutathione; Hyperplasia; Liver; Liver Neoplasms; Male; Methyldimethylaminoazobenzene; Neoplasms, Experimental; p-Dimethylaminoazobenzene; Portacaval Shunt, Surgical; Rats | 1978 |
Effect of citric acid on 3'-methyl-4-dimethylaminoazobenzene induced decrease in rat liver pH.
Topics: Animals; Citrates; Hydrogen-Ion Concentration; Liver; Male; Methyldimethylaminoazobenzene; p-Dimethylaminoazobenzene; Rats | 1979 |
Effect of phenobarbital and 3-methylcholanthrene on decrease in pH in liver induced by 3'-methyl-4-dimethylaminoazobenzene, of partial hepatectomy and hepatotoxic agents.
Topics: Animals; Chemical and Drug Induced Liver Injury; Hepatectomy; Hydrogen-Ion Concentration; In Vitro Techniques; Liver; Methylcholanthrene; Methyldimethylaminoazobenzene; p-Dimethylaminoazobenzene; Phenobarbital; Rats | 1979 |
Excretion of alpha-foetoprotein in the urine of rats during exposure to 3'-methyl-4-dimethylaminoazobenzene.
Topics: alpha-Fetoproteins; Animals; Carcinoma, Hepatocellular; Female; Liver Neoplasms; Methyldimethylaminoazobenzene; Neoplasms, Experimental; p-Dimethylaminoazobenzene; Rats; Time Factors | 1977 |
A distinctive antigen present in liver carcinomas induced by 3'-methyl-p-dimethylaminoazobenzene.
Topics: Adenoma, Bile Duct; alpha-Fetoproteins; Animals; Antibodies, Neoplasm; Antigens, Neoplasm; Carcinoma, Hepatocellular; Epitopes; Immunodiffusion; Immunoelectrophoresis; Liver Neoplasms; Male; Methyldimethylaminoazobenzene; Neoplasms, Experimental; p-Dimethylaminoazobenzene; Rats; Rats, Inbred Strains | 1977 |
Detection by antihapten antibodies of liver-bound compounds related to azocarcinogens or their metabolites.
Topics: Animals; Antibodies; Azo Compounds; Epitopes; Haptens; Liver; Male; Methyldimethylaminoazobenzene; p-Aminoazobenzene; p-Dimethylaminoazobenzene; Rats; Rats, Inbred Strains | 1979 |
Relationship between alpha-fetoprotein positive cells and precancerous lesions in rat liver during 3'-methyl-4-dimethylaminoazobenzene carcinogenesis.
Topics: alpha-Fetoproteins; Animals; Cell Transformation, Neoplastic; Female; Fluorescent Antibody Technique; Liver Neoplasms; Methyldimethylaminoazobenzene; Neoplasms, Experimental; p-Dimethylaminoazobenzene; Precancerous Conditions; Rats; Time Factors | 1979 |
Adenine purine nucleotide cycle enzymes and 3' -methyl-4-dimethylaminoazobenzene injections.
Topics: Adenosine Monophosphate; AMP Deaminase; Animals; Aspartic Acid; Female; Inosine Monophosphate; Ligases; Liver; Lyases; Methyldimethylaminoazobenzene; Nucleotide Deaminases; p-Dimethylaminoazobenzene; Rats; Saccharomyces cerevisiae; Succinates | 1978 |
Histopathological and ultrastructural study on extramedullary hematopoietic foci in early stage of 3'-methyl-4-(dimethylamino)azobenzene hepatocarcinogenesis.
Topics: Animals; Cytoplasm; Hematopoietic System; Liver; Liver Neoplasms; Male; Methyldimethylaminoazobenzene; Neoplasms, Experimental; p-Dimethylaminoazobenzene; Rats | 1978 |
Promotion by dietary phenobarbital of hepatocarcinogenesis by 2-methyl-N,N-dimethyl-4-aminoazobenzene in the rat.
Topics: Animals; Drug Synergism; Liver Neoplasms, Experimental; Male; Methyldimethylaminoazobenzene; p-Dimethylaminoazobenzene; Phenobarbital; Rats | 1979 |
Histopathology of the rat liver following a single autoprotective dose of 3'-methyl-4-dimethylaminoazobenzene.
Topics: Animals; Chemical and Drug Induced Liver Injury; Liver; Liver Diseases; Liver Neoplasms; Male; Methyldimethylaminoazobenzene; p-Dimethylaminoazobenzene; Rats; Rats, Inbred Strains; Time Factors | 1978 |
Analysis of biliary and urinary metabolites of 3'-methyl-4-(dimethylamino)azobenzene in rats.
Topics: Administration, Oral; Aminobenzoates; Animals; Azo Compounds; Bile; Male; Methyldimethylaminoazobenzene; Oxidation-Reduction; p-Dimethylaminoazobenzene; Rats; Toluene | 1978 |
Differential perturbation of erythrocyte membrane-associated transport and enzyme activities by structurally related lipophilic compounds.
Topics: Acetylcholine; Acetylcholinesterase; Biological Transport, Active; Blood Glucose; Erythrocyte Membrane; Erythrocytes; Humans; Kinetics; Methyldimethylaminoazobenzene; p-Dimethylaminoazobenzene; Temperature | 1979 |
Monoamine oxidase activity in liver of rats given 3'-methyl-4-dimethylamino azobenzene (3'-Me-DAB) in the diet.
Topics: Animals; Clorgyline; Diet; Liver; Male; Methyldimethylaminoazobenzene; Monoamine Oxidase; p-Dimethylaminoazobenzene; Rats; Time Factors | 1979 |
Metabolic activation of the hepatocarcinogen 3'-methyl-4-dimethylaminoazobenzene by a rat liver cell-free system. Evidence suggesting the formation of at least two electrophilic metabolites.
Topics: Animals; Biotransformation; Cell-Free System; Kinetics; Liver; Methyldimethylaminoazobenzene; p-Dimethylaminoazobenzene; Protein Binding; Rats; RNA | 1979 |
Release of repetitive nuclear RNA into the cytoplasm in liver of rats fed 3'-methyl-4-dimethylaminoazobenzene.
Topics: Animals; Base Sequence; Cell Nucleus; Cell Transformation, Neoplastic; Cytoplasm; Liver; Male; Methyldimethylaminoazobenzene; Molecular Weight; Nucleic Acid Hybridization; p-Dimethylaminoazobenzene; Rats; RNA; Time Factors | 1979 |
Inhibition of 3'-methyl-4-dimethylaminoazobenzene (3'MeDAB)-induced hepatocarcinogenesis in the rat: chloramphenicol inhibits N,N-dimethylaniline N-oxidase and in vitro binding of [3H]3'MeDAB to protein but not to RNA.
Topics: Aniline Compounds; Animals; Chloramphenicol; Diet; In Vitro Techniques; Liver Neoplasms; Male; Methyldimethylaminoazobenzene; Microsomes, Liver; Neoplasms, Experimental; Oxygenases; p-Dimethylaminoazobenzene; Protein Binding; Rats; RNA | 1979 |
Radiorespirometric analysis of glucose metabolism in the rat during feeding with 3'-methyl-4-(dimethylamino)azobenzene--radiorespirometry after partial hepatectomy.
Topics: Animals; Carbon Radioisotopes; DNA; Glucose; Glucosephosphate Dehydrogenase; Hepatectomy; Hexokinase; Liver; Liver Regeneration; Male; Methyldimethylaminoazobenzene; p-Dimethylaminoazobenzene; Pyruvate Kinase; Rats; Spirometry; Thymidine; Tritium | 1979 |
Enhancing effect of phenobarbital on the development of enzyme-altered islands and hepatocellular carcinomas initiated by 3'-methyl-4-(dimethylamino) azobenzene or diethylnitrosamine.
Topics: Adenosine Triphosphatases; Animals; Diethylnitrosamine; Drug Synergism; Liver; Liver Neoplasms, Experimental; Male; Methyldimethylaminoazobenzene; Nitrosamines; p-Dimethylaminoazobenzene; Phenobarbital; Precancerous Conditions; Rats | 1978 |
[Proceedings: Differentation of LDH pI isozyme in 3'-MeDAB-induced liver neoplasms].
Topics: Animals; Carcinoma, Hepatocellular; Isoenzymes; L-Lactate Dehydrogenase; Liver Neoplasms; Methyldimethylaminoazobenzene; Neoplasms, Experimental; p-Dimethylaminoazobenzene; Rats | 1975 |
Effect of Capsella bursa-pastoris on liver catalase activity in rats fed 3'-methyl-4-(dimethylamino)azobenzene.
Topics: Animals; Carcinoma, Hepatocellular; Catalase; China; Japan; Liver; Liver Neoplasms; Male; Methyldimethylaminoazobenzene; Neoplasms, Experimental; p-Dimethylaminoazobenzene; Plant Extracts; Plants, Medicinal; Rats | 1975 |
Effect of treatment of rats with some chemical carcinogens on the stimulatory effect of adrenaline on cyclic AMP accumulation in liver slices.
Topics: 2-Acetylaminofluorene; Animals; Carcinogens; Cyclic AMP; Epinephrine; Liver; Male; Methyldimethylaminoazobenzene; p-Dimethylaminoazobenzene; Rats; Stimulation, Chemical; Theophylline | 1975 |
Binding of the azocarcinogen 3'-methyl-p-dimethylaminoazobenzene to cellular components of normal rat liver and azocarcinogen-induced hepatomas.
Topics: Adenoma, Bile Duct; Animals; Binding Sites; Carcinoma, Hepatocellular; Cell Membrane; Cell Nucleus; Cytoplasm; Fluorescent Antibody Technique; Immunodiffusion; Kidney; Liver; Liver Neoplasms; Male; Methyldimethylaminoazobenzene; Neoplasms, Experimental; p-Dimethylaminoazobenzene; Rats; Rats, Inbred Strains | 1975 |
Change in the mixed function oxidase system of liver microsomes in rats treated with 3'-methyl-4-dimethylaminoazobenzene.
Topics: Administration, Oral; Animals; Cytochrome P-450 Enzyme System; Cytochromes; Electron Spin Resonance Spectroscopy; Endoplasmic Reticulum; Female; Golgi Apparatus; Infusions, Parenteral; Liver; Male; Methyldimethylaminoazobenzene; Microsomes, Liver; Mixed Function Oxygenases; Organ Size; Oxidoreductases; p-Dimethylaminoazobenzene; Rats | 1976 |
Some properties and electrophoretic patterns of rat liver esterases in relation to hepatocarcinogenesis by 3'-methyl-4-(dimethylamino) azobenzene.
Topics: Acetates; Animals; Carcinoma, Hepatocellular; Cholinesterases; Cysteine; Electrophoresis, Cellulose Acetate; Enzyme Activation; Esterases; Liver; Liver Neoplasms; Male; Methyldimethylaminoazobenzene; Naphthaleneacetic Acids; Neoplasms, Experimental; p-Dimethylaminoazobenzene; Rats | 1976 |
Influence of riboflavin antagonists on azo dye hepatoma induction in the rat.
Topics: Animals; Carcinoma, Hepatocellular; Flavins; Liver Neoplasms; Male; Methyldimethylaminoazobenzene; Neoplasms, Experimental; p-Dimethylaminoazobenzene; Rats; Riboflavin; Structure-Activity Relationship | 1976 |
Induction of liver tumours by 3'-methyl-dimethylaminoazobenzene (3'-Me-DAB) in rats chronically infected with Toxoplasma or Besnoitia.
Topics: Adenoma, Bile Duct; Animals; Carcinoma, Hepatocellular; Chronic Disease; Diet; Liver Neoplasms; Male; Methyldimethylaminoazobenzene; p-Dimethylaminoazobenzene; Protozoan Infections; Rats; Toxoplasmosis | 1977 |
Cholangiocarcinomas induced by feeding 3'-methyl-4-dimethylaminoazobenzene to rats. Histopathology and ultrastructure.
Topics: Adenoma, Bile Duct; Animals; Basement Membrane; Cell Membrane; Cell Nucleus; Diet; Golgi Apparatus; Liver; Liver Neoplasms; Male; Methyldimethylaminoazobenzene; Mitochondria; Neoplasms, Experimental; p-Dimethylaminoazobenzene; Rats | 1977 |
Effects of selenium on azo dye hepatocarcinogenesis.
Topics: Animals; Benz(a)Anthracenes; Carcinoma, Hepatocellular; Liver Neoplasms; Male; Methyldimethylaminoazobenzene; p-Dimethylaminoazobenzene; Rats; Selenium | 1977 |
Protein composition of nuclear ribonucleoprotein particles isolated from liver of rats in the early stages of feeding of 3'-methyl-4-dimethylaminoazobenzene and from hepatoma induced by the same carcinogen.
Topics: Animals; Carcinoma, Hepatocellular; Cell Nucleus; Cell Transformation, Neoplastic; Electrophoresis, Polyacrylamide Gel; Liver; Liver Neoplasms; Methyldimethylaminoazobenzene; Neoplasm Proteins; Nucleoproteins; p-Dimethylaminoazobenzene; Rats; Ribonucleoproteins; Sodium Dodecyl Sulfate; Spectrum Analysis | 1977 |
Appearance of intestinal type of tumor cells in hepatoma tissue induced by 3'-methyl-4-dimethylaminoazobenzene.
Topics: Alkaline Phosphatase; Animals; Carcinoma, Hepatocellular; Cytoplasmic Granules; Intestines; Isoenzymes; Liver Neoplasms; Male; Methyldimethylaminoazobenzene; Microscopy, Electron; Microvilli; Neoplasms, Experimental; p-Dimethylaminoazobenzene; Rats | 1978 |
A study of cyclic nucleotide metabolism and the histology of rat liver during 3'-methyl-4-dimethylamino-azobenzene carcinogenesis. I. Histology.
Topics: Adenoma, Bile Duct; Animals; Cell Nucleus; Epithelium; Liver; Liver Glycogen; Liver Neoplasms; Male; Methyldimethylaminoazobenzene; Mitosis; p-Dimethylaminoazobenzene; Rats | 1978 |
A study of cyclic nucleotide metabolism and the histology of rat liver during 3'-methyl-4-dimethylamino-azobenzene carcinogenesis. II. Cyclic AMP metabolism.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adenoma, Bile Duct; Adenylyl Cyclases; Animals; Cyclic AMP; Female; Guanylyl Imidodiphosphate; Isoproterenol; Liver; Liver Neoplasms; Methyldimethylaminoazobenzene; p-Dimethylaminoazobenzene; Rats | 1978 |
Localization of minor liver-bound metabolites of 3-methyl-p-dimethylaminoazobenzene with anti-hapten antibodies.
Topics: Aniline Compounds; Animals; Antibodies; Antibody Specificity; Azo Compounds; Cytosol; Diet; Fluorescent Antibody Technique; Haptens; Immunosorbent Techniques; Liver; Male; Methyldimethylaminoazobenzene; p-Dimethylaminoazobenzene; Rats; Riboflavin | 1977 |
Mitochondrial membrane-linked reactions in carcinogenesis: change in steroselective uncoupling of oxidative phosphorylation by aliphatic dicarbonyls and in the Arrhenius plot of NADH-indophenol reductase.
Topics: 2,6-Dichloroindophenol; Animals; Dithioerythritol; Glutamates; Ketoglutaric Acids; Ketones; Kinetics; Male; Membranes; Methyldimethylaminoazobenzene; Mitochondria, Liver; NADH, NADPH Oxidoreductases; Oxidative Phosphorylation; Oxygen Consumption; p-Dimethylaminoazobenzene; Pyruvates; Rats; Stereoisomerism; Structure-Activity Relationship; Succinates; Thermodynamics | 1977 |
The effect of propranolol on induction of rat liver tumors by a chemical carcinogen.
Topics: Animals; Diet; Drug Interactions; Liver Neoplasms; Male; Methyldimethylaminoazobenzene; Neoplasms, Experimental; p-Dimethylaminoazobenzene; Propranolol; Rats; Time Factors | 1977 |
Evidence for a receptor protein of activated carcinogen.
Topics: Animals; Cytosol; Kinetics; Liver; Male; Methyldimethylaminoazobenzene; p-Dimethylaminoazobenzene; Precipitin Tests; Rats; Receptors, Drug | 1977 |
Modifications of 3'-methyl-4-dimethylaminoazobenzene carcinogenesis of rat liver and carcinogen metabolism by portacaval anastomosis.
Topics: Animals; Body Weight; Inactivation, Metabolic; Liver; Liver Neoplasms; Male; Methyldimethylaminoazobenzene; Microsomes, Liver; Neoplasms, Experimental; Organ Size; p-Dimethylaminoazobenzene; Portacaval Shunt, Surgical; Protein Binding; Rats | 1977 |
Effect of l-tryptophan on diethylnitrosamine and 3'-methyl-4-n-dimethylaminoazobenzene hepatocarcinogenesis.
Topics: Animals; Antineoplastic Agents; Diethylnitrosamine; Liver; Liver Neoplasms; Male; Methyldimethylaminoazobenzene; Nitrosamines; Organ Size; p-Dimethylaminoazobenzene; Rats; Tryptophan | 1977 |
Enhancement of azo dye carcinogenesis by dietary sodium sulphate.
Topics: Acetanilides; Animals; Azo Compounds; Body Weight; Diet; Drug Synergism; Liver; Liver Cirrhosis; Liver Neoplasms; Lung Neoplasms; Male; Methyldimethylaminoazobenzene; Neoplasm Metastasis; Neoplasms, Experimental; Organ Size; p-Dimethylaminoazobenzene; Precancerous Conditions; Rats; Reaction Time; Sodium; Spleen; Sulfates | 1975 |
The effect of dietary vitamin E on glutathione-induced liver mitochondrial swelling from mice treated with 3'-4-methyl-4-dimethylaminoazobenzene.
Topics: Animals; Diet; Glutathione; Male; Methyldimethylaminoazobenzene; Mice; Mitochondria; Mitochondria, Liver; Mitochondrial Swelling; p-Dimethylaminoazobenzene; Time Factors; Vitamin E; Vitamin E Deficiency | 1975 |
Modification of toxic liver injury in the rat II. Protective effect of cycloheximide on ethionine-induced damage and autoprotective effects of high doses of ethionine, 3'-methyl-4-dimethylaminoazobenzene, and 2-acetylaminofluorene.
Topics: 2-Acetylaminofluorene; Animals; Chemical and Drug Induced Liver Injury; Ethionine; Fluorenes; In Vitro Techniques; Liver; Male; Methionine; Methyldimethylaminoazobenzene; p-Dimethylaminoazobenzene; Rats; Time Factors | 1975 |
Fine structural changes induced in rat hepatocytes by single doses of 3'-methyl-4-dimethylaminoazobenzene.
Topics: Animals; Cytoplasm; Endoplasmic Reticulum; Liver; Liver Glycogen; Male; Methyldimethylaminoazobenzene; p-Dimethylaminoazobenzene; Rats | 1975 |
Binding of 3'-methyl-4-dimethylaminoazobenzene to nuclear ribonucleoprotein particles.
Topics: Animals; Cell Nucleus; Liver; Male; Methyldimethylaminoazobenzene; Nucleoproteins; p-Dimethylaminoazobenzene; Rats; Ribonucleoproteins | 1976 |
A phenylalanine transfer RNA azo dye complex in livers of rats fed diets containing 3'-methyl-4-dimethylaminoazobenzene.
Topics: Animals; Azo Compounds; Binding Sites; Chromatography, DEAE-Cellulose; Cytosine; Diet; Female; Liver; Male; Methyldimethylaminoazobenzene; p-Dimethylaminoazobenzene; Phenylalanine; Rats; RNA, Transfer; Spectrophotometry; Uridine | 1976 |
Promoting effect of carbon tetrachloride on azo-dye hepatocarcinogenesis in rats.
Topics: Animals; Carbon Tetrachloride; Female; Liver Neoplasms; Methyldimethylaminoazobenzene; p-Dimethylaminoazobenzene; Polychlorinated Biphenyls; Rats | 1976 |
Role of age and sex in chronic thyroiditis in rats fed 3'-methyl-4-dimethylaminoazobenzene.
Topics: Age Factors; Animals; Female; Male; Methyldimethylaminoazobenzene; p-Dimethylaminoazobenzene; Rats; Rats, Inbred BUF; Rats, Inbred Strains; Rodent Diseases; Sex Factors; Thyroid Gland; Thyroiditis | 1976 |
Protein composition of liver nuclear ribonucleoportein particles of rats fed carcinogenic aminoazo dyes.
Topics: Animals; Azo Compounds; Cell Nucleus; Liver; Male; Methyldimethylaminoazobenzene; Molecular Weight; Nucleoproteins; p-Aminoazobenzene; p-Dimethylaminoazobenzene; Protein Biosynthesis; Proteins; Rats; Ribonucleoproteins; RNA | 1976 |
Studies on carcinogenic azo dyes. VI. Effect of factors influencing drug metabolism on the NIH shift during hydroxylations of 4-dimethylamino-3'-methylazobenzene and 3-methylacetanilide.
Topics: Acetanilides; Animals; Chemical Phenomena; Chemistry; Cricetinae; Deuterium; Female; Hydroxylation; In Vitro Techniques; Male; Methyldimethylaminoazobenzene; Mice; Microsomes, Liver; p-Dimethylaminoazobenzene; Rabbits; Rats; Tritium | 1976 |
Studies on carcinogenic azo dyes. V. The NIH shift during the aryl hydroxylation of 3'-methyl-4-(dimethylamino)azobenzene and 3-methylacetanilide by the rat.
Topics: Acetanilides; Animals; Carcinogens; Deuterium; Hydroxylation; In Vitro Techniques; Male; Methyldimethylaminoazobenzene; Microsomes, Liver; p-Dimethylaminoazobenzene; Rats; Tritium | 1976 |
Thymidine kinase and alpha-fetoprotein as biochemical markers of hepatocarcinogenesis induced by 3'-methyl-4-dimethylaminoazobenzene treatment in rats.
Topics: alpha-Fetoproteins; Animals; Biomarkers, Tumor; Isoenzymes; Kinetics; Liver; Liver Neoplasms, Experimental; Male; Methyldimethylaminoazobenzene; Molecular Weight; p-Dimethylaminoazobenzene; Rats; Rats, Inbred Strains; Reference Values; Thymidine Kinase; Time Factors | 1990 |
The appearance of hepatoma-associated chromosomal non-histone proteins in rat liver after a single dose of 3'-MDAB followed by treatment of phenobarbital.
Topics: alpha-Fetoproteins; Animals; Biomarkers, Tumor; Cell Nucleus; Chromatin; Chromosomal Proteins, Non-Histone; Cocarcinogenesis; Enzyme-Linked Immunosorbent Assay; Fluorescent Antibody Technique; Hepatectomy; Immunoblotting; Liver; Liver Neoplasms, Experimental; Male; Methyldimethylaminoazobenzene; p-Dimethylaminoazobenzene; Phenobarbital; Precancerous Conditions; Rats; Rats, Inbred Strains; Time Factors | 1990 |
Appearance of a carcinoid-like pattern in rat hepatic tumors induced by 3'-methyl-4-dimethyl-aminoazobenzene.
Topics: Animals; Carcinoid Tumor; Liver Neoplasms, Experimental; Male; Methyldimethylaminoazobenzene; p-Dimethylaminoazobenzene; Rats; Silver | 1991 |
Retinyl acetate inhibition of 3'-methyl-4-dimethyl-aminoazobenzene induced hepatic neoplasia.
Topics: Adenylosuccinate Lyase; Animals; Diterpenes; Female; gamma-Glutamyltransferase; Liver; Liver Neoplasms, Experimental; Methyldimethylaminoazobenzene; N-Acetylneuraminic Acid; p-Dimethylaminoazobenzene; Precancerous Conditions; Rats; Rats, Inbred Strains; Retinyl Esters; Sialic Acids; Time Factors; Vitamin A | 1990 |
Studies on the hyperplastic responsiveness of binucleated rat hepatocytes.
Topics: Animals; Butyrates; Cell Cycle; Cell Nucleus; Clofenapate; Hyperplasia; Liver; Male; Methyldimethylaminoazobenzene; p-Dimethylaminoazobenzene; Rats | 1990 |
Analysis of cytological changes in hepatocytes from rats dosed with 3'-methyl-4-dimethylaminoazobenzene: initial response appears to involve cytokinesis of binucleated cells.
Topics: Administration, Oral; Animals; Cell Cycle; Cell Nucleus; Interphase; Liver; Male; Methyldimethylaminoazobenzene; p-Dimethylaminoazobenzene; Ploidies; Rats | 1990 |
[Induction of phenotypic changes and effect of AFP gene expression in newborn rat liver cells with N-methyl-N-nitro-N-nitrosoguanidine and 3'-methyl-4-dimethylaminoazobenzene in vitro].
Topics: alpha-Fetoproteins; Animals; Cell Line; Gene Expression Regulation; Liver; Methyldimethylaminoazobenzene; Methylnitronitrosoguanidine; p-Dimethylaminoazobenzene; Phenotype; Rats; Rats, Inbred Strains | 1986 |
Effects of 3'-methyl-4-dimethylaminoazobenzene on RNA processing in rat liver nuclei.
Topics: Animals; Cell Nucleus; Liver; Male; Methyldimethylaminoazobenzene; p-Dimethylaminoazobenzene; Rats; RNA; RNA, Small Nuclear | 1987 |
Transformation of cultured fetal rat liver cells by MDAB and phenobarbital. Morphological, biochemical and immunocytochemical characterization of cell lines.
Topics: Animals; Blotting, Northern; Cell Line; Cell Transformation, Neoplastic; Cells, Cultured; Culture Techniques; DNA; Fetus; gamma-Glutamyltransferase; Liver; Methyldimethylaminoazobenzene; Nucleic Acid Hybridization; p-Dimethylaminoazobenzene; Phenobarbital; Rats; Rats, Inbred Strains; RNA; Tyrosine Transaminase | 1989 |
Change in the ploidy state of rat liver cells during chemical hepatocarcinogenesis and its relationship to the increased expression of alpha-fetoprotein.
Topics: alpha-Fetoproteins; Animals; Flow Cytometry; Gene Expression; Immunoenzyme Techniques; Liver; Liver Neoplasms, Experimental; Methyldimethylaminoazobenzene; p-Dimethylaminoazobenzene; Ploidies; Rats | 1989 |
Quantitative electron microscopy of carcinogen-induced alterations in hepatocyte rough endoplasmic reticulum. II. Modulation of the effects of 3'MeDAB by adrenalectomy and adrenal corticosteroids.
Topics: Adrenalectomy; Animals; Desoxycorticosterone; Endoplasmic Reticulum; Liver; Male; Methyldimethylaminoazobenzene; Microscopy, Electron; p-Dimethylaminoazobenzene; Rats | 1989 |
Effect of ethanol on hepatocarcinogenesis initiated in rats with 3'-methyl-4-dimethylaminoazobenzene in the absence of liver injuries.
Topics: Animals; Cholesterol; Drug Synergism; Ethanol; Liver; Liver Neoplasms, Experimental; Male; Methyldimethylaminoazobenzene; p-Dimethylaminoazobenzene; Pyruvate Kinase; Rats; Rats, Inbred Strains; Time Factors; Triglycerides | 1989 |
[Biochemical and immunohistochemical studies on alteration of aldolase isozymes in rat liver in the process of hepatocarcinogenesis by administration of a diet containing 3'-methyl-4-dimethylaminoazobenzene].
Topics: Animals; Fructose-Bisphosphate Aldolase; Isoenzymes; Liver; Liver Neoplasms; Male; Methyldimethylaminoazobenzene; p-Dimethylaminoazobenzene; Radioimmunoassay; Rats; Rats, Inbred Strains | 1989 |
Inhibitory effect of fumaric acid on 3'-methyl-4-(dimethylamino)azobenzene-induced hepatocarcinogenesis in rats.
Topics: Animals; Antineoplastic Agents; Fumarates; Liver Neoplasms, Experimental; Male; Methyldimethylaminoazobenzene; p-Dimethylaminoazobenzene; Rats | 1989 |
Decreased activation of carcinogens in the liver of carcinogen-resistant rats.
Topics: 2-Acetylaminofluorene; Animals; Blotting, Northern; Cytochrome P-450 Enzyme System; DNA; DNA Probes; Drug Resistance; Liver; Methyldimethylaminoazobenzene; Microsomes, Liver; p-Dimethylaminoazobenzene; Rats; Receptors, Aryl Hydrocarbon; Receptors, Drug; RNA, Messenger | 1989 |
Induction of hepatocellular carcinoma in nonhuman primates by chemical carcinogens.
Topics: 2-Acetylaminofluorene; Aflatoxins; Animals; Carcinogens, Environmental; Carcinoma, Hepatocellular; Chlorocebus aethiops; Environmental Pollutants; Female; Food Additives; Liver Neoplasms; Macaca fascicularis; Macaca mulatta; Male; Methylazoxymethanol Acetate; Methyldimethylaminoazobenzene; Nitrosamines; p-Dimethylaminoazobenzene; Sterigmatocystin; Urethane | 1989 |
Transformation of primary cultured and co-cultured adult rat liver cells by 3'-methyl-4-dimethylaminoazobenzene.
Topics: Animals; Cell Transformation, Neoplastic; Cells, Cultured; Chromosome Aberrations; DNA; Female; gamma-Glutamyltransferase; Liver; Male; Methyldimethylaminoazobenzene; p-Dimethylaminoazobenzene; Rats | 1985 |
Promoting effects of phenobarbital and 3'-methyl-4-dimethylaminoazobenzene on the appearance of gamma-glutamyltranspeptidase positive foci in rat liver pretreated with varying doses of diethylnitrosamine.
Topics: Animals; Cocarcinogenesis; Diethylnitrosamine; gamma-Glutamyltransferase; Liver; Liver Neoplasms, Experimental; Male; Methyldimethylaminoazobenzene; Organ Size; p-Dimethylaminoazobenzene; Phenobarbital; Precancerous Conditions; Rats; Rats, Inbred F344 | 1985 |
Effect of phenobarbital on adult rat liver cells treated with 3'-methyl-4-dimethylaminoazobenzene in primary culture.
Topics: Animals; Cells, Cultured; Chromosome Aberrations; Dimethyl Sulfoxide; Dose-Response Relationship, Drug; Drug Synergism; gamma-Glutamyltransferase; Liver; Male; Methyldimethylaminoazobenzene; Microscopy, Phase-Contrast; p-Dimethylaminoazobenzene; Phenobarbital; Rats; Rats, Inbred Strains | 1985 |
Decreased induction of gamma-glutamyltransferase activity by 3'-methyl-4-dimethylaminoazobenzene in the liver of rats given carcinogen-containing diet for several generations.
Topics: Animals; Animals, Newborn; Drug Resistance; Enzyme Induction; Female; gamma-Glutamyltransferase; Glucocorticoids; Liver; Liver Neoplasms, Experimental; Male; Methyldimethylaminoazobenzene; p-Dimethylaminoazobenzene; Precancerous Conditions; Rats; Rats, Inbred Strains | 1986 |
Promotion of 3'-methyl-4-dimethylaminoazobenzene-initiated adult rat liver cells to malignant state by phenobarbital in culture.
Topics: Animals; Cell Cycle; Cell Transformation, Neoplastic; Epithelium; gamma-Glutamyltransferase; Liver; Liver Neoplasms, Experimental; Methyldimethylaminoazobenzene; p-Dimethylaminoazobenzene; Phenobarbital; Rats | 1986 |
Effect of administration of 2-methyl-4-dimethylaminoazobenzene on the half-lives of rat liver mitochondria and cytochrome oxidase.
Topics: Animals; Arginase; Bicarbonates; Carbon Radioisotopes; Electron Transport Complex IV; Half-Life; Kinetics; Liver; Male; Methionine; Methyldimethylaminoazobenzene; Mitochondria, Liver; p-Dimethylaminoazobenzene; Protein Biosynthesis; Rats; Sulfur Radioisotopes | 1985 |
Azo dye-induced alterations in vitamin B-6 metabolism and in pyridoxal 5'-phosphate-binding proteins in rat liver.
Topics: Animals; Cytosol; Densitometry; Enzyme-Linked Immunosorbent Assay; Liver; Liver Neoplasms, Experimental; Male; Methyldimethylaminoazobenzene; Ornithine Decarboxylase; p-Dimethylaminoazobenzene; Pyridoxal Kinase; Pyridoxal Phosphate; Pyridoxaminephosphate Oxidase; Pyridoxine; Rats; Receptors, Cell Surface | 1986 |
Malignant transformation of rat liver cells by N-benzoyloxy-3'-methyl-4-methylaminoazobenzene and its related compound.
Topics: Animals; Carcinogens; Cell Transformation, Neoplastic; Cells, Cultured; Chromosome Aberrations; DNA Repair; Liver; Methyldimethylaminoazobenzene; p-Dimethylaminoazobenzene; Rats | 1986 |
Early modifications of gene expression induced in liver by azo-dye diet.
Topics: Animals; Fructose-Bisphosphate Aldolase; Gene Expression Regulation; Kinetics; Liver; Methyldimethylaminoazobenzene; p-Dimethylaminoazobenzene; Phosphoenolpyruvate Carboxykinase (GTP); Pyruvate Kinase; Rats; RNA, Messenger | 1986 |
Detection of mRNAs present at low concentrations in rat liver by in situ hybridization: application to the study of metabolic regulation and azo dye hepatocarcinogenesis.
Topics: Animals; DNA; DNA, Recombinant; Fructose-Bisphosphate Aldolase; Liver; Liver Neoplasms, Experimental; Male; Methyldimethylaminoazobenzene; Nucleic Acid Hybridization; p-Dimethylaminoazobenzene; Pyruvate Kinase; Rats; RNA, Messenger | 1987 |
Promotion of hepatocarcinogenesis by suxibuzone in rats initiated with 3'-methyl-4-dimethylaminoazobenzene.
Topics: Administration, Oral; Animals; Body Weight; Carcinogens; Drug Interactions; Liver; Liver Neoplasms; Male; Methyldimethylaminoazobenzene; Organ Size; p-Dimethylaminoazobenzene; Phenobarbital; Phenylbutazone; Pyruvate Kinase; Rats; Rats, Inbred Strains | 1987 |
Hepatocarcinogenic activities of hydroxymethyl derivatives of 4-(N,N-dimethylamino)azobenzene in ACI/N rats.
Topics: Animals; Biotransformation; Carcinogens; Hydroxylation; Liver Neoplasms, Experimental; Methyldimethylaminoazobenzene; p-Dimethylaminoazobenzene; Rats; Rats, Inbred ACI | 1987 |
The binding of an aminoazo dye carcinogen to a specific methionine residue in rat liver alcohol dehydrogenase in vivo.
Topics: Alcohol Dehydrogenase; Amino Acid Sequence; Animals; Binding Sites; Kinetics; Liver; Male; Mass Spectrometry; Methionine; Methyldimethylaminoazobenzene; p-Dimethylaminoazobenzene; Rats; Rats, Inbred Strains | 1987 |
A study of the regulation of the glucose transporter in the plasma membranes of hepatoma cells induced by 3'-Me DAB.
Topics: Animals; Cell Membrane; Liver Neoplasms, Experimental; Male; Methyldimethylaminoazobenzene; Microsomes, Liver; Monosaccharide Transport Proteins; p-Dimethylaminoazobenzene; Rats; Rats, Inbred Strains | 1987 |
Quantitative electron microscopy of carcinogen-induced alterations in hepatocyte rough endoplasmic reticulum. I. Chronic effect of 3'MeDAB and short-term effects of azo dyes of different carcinogenic potentials.
Topics: Animals; Endoplasmic Reticulum; Liver; Liver Neoplasms, Experimental; Male; Methyldimethylaminoazobenzene; Microscopy, Electron; Organ Size; p-Dimethylaminoazobenzene; Rats; Rats, Inbred Strains | 1988 |
Effect of fasting on aggregation of hepatocyte rough endoplasmic reticulum in adrenalectomized and 3'MeDAB-treated rats: quantitative electron microscope study.
Topics: Adrenalectomy; Animals; Endoplasmic Reticulum; Fasting; Liver; Male; Methyldimethylaminoazobenzene; Microscopy, Electron; p-Dimethylaminoazobenzene; Rats; Rats, Inbred Strains | 1988 |
Age related variations of hepatocarcinogenic effect of azo dye (3'-MDAB) as linked to the level of hepatocyte polyploidization.
Topics: Aging; Animals; Histones; Liver; Liver Neoplasms, Experimental; Male; Methyldimethylaminoazobenzene; Mice; p-Dimethylaminoazobenzene; Polyploidy; Proteins; Rats; Rats, Inbred Strains | 1988 |
Irreversible depression in the ratio of tetraploid:diploid liver nuclei in rats treated with 3'-methyl-4-dimethylaminoazobenzene (3'M).
Topics: Animals; Body Weight; Cell Nucleus; Dose-Response Relationship, Drug; Liver; Male; Methyldimethylaminoazobenzene; p-Dimethylaminoazobenzene; Ploidies; Rats | 1985 |
Comparison of drug-metabolizing activities in the livers of carcinogen-sensitive parent rats and carcinogen-resistant descendants.
Topics: Animals; Benzopyrene Hydroxylase; Biotransformation; Cytochrome P-450 Enzyme System; Drug Resistance; Epoxide Hydrolases; Glutathione Transferase; Liver; Liver Neoplasms; Liver Neoplasms, Experimental; Methylcholanthrene; Methyldimethylaminoazobenzene; Mutagenicity Tests; p-Dimethylaminoazobenzene; Rats; Spectrum Analysis | 1985 |
Pattern of 2-methyl-4-dimethylaminoazobenzene-binding proteins in the livers of partially hepatectomized rats and of continuously dye-fed rats in comparison with 3'-methyl-4-dimethylaminoazobenzene.
Topics: Administration, Oral; Animals; Chromatography; Chromatography, Gel; Hepatectomy; Liver; Liver Regeneration; Male; Methane; Methyldimethylaminoazobenzene; p-Dimethylaminoazobenzene; Protein Binding; Proteins; Rats; Spectrophotometry; Time Factors | 1972 |
Studies on carcinogenic bifunctional aminoazo dyes. III. Synthesis and physico-chemical properties of (N',N'-dimethyl-4'-amino)-, (4'-amino)- and (N'-acetyl-4'-amino)-N,N-dimethyl-4-aminoazobenzene.
Topics: Azo Compounds; Carcinogens; Chemical Phenomena; Chemistry, Physical; Methyldimethylaminoazobenzene; p-Dimethylaminoazobenzene; Solubility | 1971 |
Carcinogenic activities of hydroxymethyl derivatives of 4-(dimethylamino)azobenzene in the liver of rats, mice, and hamsters.
Topics: Animals; Carcinogens; Carcinoma, Hepatocellular; Cricetinae; Dose-Response Relationship, Drug; Female; Hyperplasia; Liver; Liver Neoplasms; Male; Mesocricetus; Methyldimethylaminoazobenzene; Mice; p-Dimethylaminoazobenzene; Rats; Rats, Inbred Strains | 1984 |
Decrease in the phosphorylation of the proteins associated with heterogeneous nuclear RNA after the application of 3'-methyl-4-dimethylaminoazobenzene.
Topics: Animals; Cell Nucleus; Heterogeneous-Nuclear Ribonucleoproteins; Kinetics; Liver; Male; Methyldimethylaminoazobenzene; p-Dimethylaminoazobenzene; Phosphates; Phosphoprotein Phosphatases; Phosphorus Radioisotopes; Phosphorylation; Protein Kinases; Rats; Ribonucleoproteins; Ribonucleotides; RNA, Heterogeneous Nuclear | 1984 |
gamma-Glutamyltransferase and the inhibition of azo dye-produced neoplasia by concomitant administration of disulfiram.
Topics: Animals; Disulfiram; gamma-Glutamyltransferase; Hyperplasia; Liver; Liver Neoplasms, Experimental; Male; Methyldimethylaminoazobenzene; p-Dimethylaminoazobenzene; Precancerous Conditions; Rats | 1980 |
The effect of 3'-methyl-4-demethyl-aminoazobenzene of foetal rat hepatocytes in culture.
Topics: Animals; Cells, Cultured; Fetus; Glucose-6-Phosphatase; Liver; Methyldimethylaminoazobenzene; Microscopy, Electron; p-Dimethylaminoazobenzene; Phosphoenolpyruvate Carboxykinase (GTP); Rats; Rats, Inbred Strains; Tyrosine Transaminase | 1981 |
Effect of 3'-methyl-4-dimethylaminoazobenzene on liver cells from adult rat in primary culture.
Topics: Animals; Cell Division; Cell Survival; Cell Transformation, Neoplastic; Cells, Cultured; Chromosome Aberrations; Cytoplasm; gamma-Glutamyltransferase; Karyotyping; Liver; Methyldimethylaminoazobenzene; p-Dimethylaminoazobenzene; Rats | 1982 |
The effect of carcinogens on the accumulation of tyrosine aminotransferase by foetal rat hepatocytes in culture.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Cells, Cultured; Fetus; Liver; Methyldimethylaminoazobenzene; p-Dimethylaminoazobenzene; Rats; Rats, Inbred Strains; Receptors, Steroid; Tetradecanoylphorbol Acetate; Tyrosine Transaminase | 1982 |
In vitro transformation of adult rat liver cells by 3'-methyl-4-dimethylaminoazobenzene.
Topics: Animals; Cell Transformation, Neoplastic; Cells, Cultured; Chromosomes; gamma-Glutamyltransferase; Liver; Male; Methyldimethylaminoazobenzene; p-Dimethylaminoazobenzene; Rats; Rats, Inbred Strains | 1983 |
Expression of gamma-glutamyltranspeptidase in cultures of spontaneously and chemically transformed rat liver cells.
Topics: Animals; Cell Transformation, Neoplastic; Cells, Cultured; Epithelium; gamma-Glutamyltransferase; Liver; Methyldimethylaminoazobenzene; p-Dimethylaminoazobenzene; Rats | 1983 |
The development of mixed function amine oxidase in cultured foetal rat hepatocytes and its relation to 3'-methyl-4-N,N-dimethylaminoazobenzene effects on tyrosine aminotransferase accumulation.
Topics: Animals; Biotransformation; Cells, Cultured; Female; Fetus; Gestational Age; Liver; Methyldimethylaminoazobenzene; Mixed Function Oxygenases; Monoamine Oxidase Inhibitors; p-Dimethylaminoazobenzene; Pregnancy; Rats; Tyrosine Transaminase | 1983 |
Ultrastructure of pituitary somatotrophs of male rats during liver carcinogenesis by 3'-methyl-4-dimethylaminoazobenzene.
Topics: Animals; Cell Nucleus; Cytoplasmic Granules; Endoplasmic Reticulum; Growth Hormone; Liver Neoplasms; Male; Methyldimethylaminoazobenzene; Mitochondria; p-Dimethylaminoazobenzene; Pituitary Gland, Anterior; Radioimmunoassay; Rats; Rats, Inbred Strains | 1984 |
Effect of BCG on hepatocarcinogenesis of the rat induced by 3'-methyl-4-(dimethylamino)azobenzene.
Topics: alpha-Fetoproteins; Animals; Immunity, Cellular; Liver Neoplasms, Experimental; Male; Methyldimethylaminoazobenzene; Mycobacterium bovis; p-Dimethylaminoazobenzene; Rats; Time Factors | 1980 |
Cytological alteration of cultured rat liver cells by 3'-methyl-4-dimethylaminoazobenzene with special reference to chromosome changes, changes of growth patterns at a colony level and alpha-fetoprotein production.
Topics: alpha-Fetoproteins; Animals; Cell Division; Cell Line; Chromosome Aberrations; Liver; Methyldimethylaminoazobenzene; p-Dimethylaminoazobenzene; Rats | 1980 |
Azocarcinogen-induced release of chromatin-associated RNA into liver cytoplasm: the possible role of reiterated RNA sequences in the control of RNA processing.
Topics: Animals; Base Sequence; Chromatin; Chromosomes; Cytoplasm; DNA; Liver; Male; Methyldimethylaminoazobenzene; Nucleic Acid Hybridization; p-Dimethylaminoazobenzene; Rats; RNA | 1981 |
Antigenic changes in nonhistone proteins during azo dye hepatocarcinogenesis.
Topics: Animals; Cell Nucleus; Chromatin; Chromosomal Proteins, Non-Histone; Epitopes; Liver; Liver Neoplasms, Experimental; Male; Methyldimethylaminoazobenzene; p-Dimethylaminoazobenzene; Rats; Rats, Inbred F344 | 1982 |
The expression of alpha-fetoprotein and albumin genes in rat liver during chemical carcinogenesis.
Topics: alpha-Fetoproteins; Animals; Kinetics; Liver; Liver Neoplasms, Experimental; Methyldimethylaminoazobenzene; Nucleic Acid Hybridization; p-Dimethylaminoazobenzene; Precancerous Conditions; Rats; Rats, Inbred F344; RNA, Messenger; Serum Albumin; Transcription, Genetic | 1982 |
A series of inhibitors of azo dye hepatocarcinogenesis partially reverse the azo dye-induced decrease in liver RNA/DNA ratio.
Topics: Acetanilides; Animals; Antineoplastic Agents; Butylated Hydroxytoluene; DNA; Hydroxypropiophenone; Liver; Liver Neoplasms; Male; Methylcholanthrene; Methyldimethylaminoazobenzene; p-Dimethylaminoazobenzene; Rats; Rats, Inbred Strains; RNA | 1982 |
Cytokeratin and nonhistone protein antigenic changes in rat liver during azo dye but not hepatotoxin feeding.
Topics: 1-Naphthylisothiocyanate; Animals; Antigens; Chromosomal Proteins, Non-Histone; Keratins; Liver; Liver Neoplasms, Experimental; Male; Methyldimethylaminoazobenzene; p-Dimethylaminoazobenzene; Rats; Rats, Inbred F344; Rats, Inbred Strains | 1983 |
Nucleocytoplasmic release of repetitive DNA transcripts in carcinogenesis correlates with a 60 kilodalton cytoplasmic protein.
Topics: Animals; Cell Nucleus; Cytoplasm; Cytosol; Female; Kinetics; Liver; Liver Neoplasms, Experimental; Male; Mammary Neoplasms, Experimental; Methyldimethylaminoazobenzene; p-Dimethylaminoazobenzene; Proteins; Rats; Rats, Inbred Strains; Repetitive Sequences, Nucleic Acid; RNA; RNA, Messenger; RNA, Ribosomal; RNA, Transfer; Transcription Factors | 1984 |
Induction of hyperplastic liver nodules in hepatectomized rats treated with 3'-methyl-4-dimethylaminoazobenzene, benzo[a]pyrene or phenobarbital before or after exposure to N-2-fluorenylacetamide.
Topics: 2-Acetylaminofluorene; Animals; Benzo(a)pyrene; Benzopyrenes; Carbon Tetrachloride; Hepatectomy; Hyperplasia; Liver; Liver Neoplasms; Male; Methyldimethylaminoazobenzene; p-Dimethylaminoazobenzene; Phenobarbital; Rats; Rats, Inbred F344 | 1982 |
Induction of tumors in transplacental or neonatal mice administered 3'-methyl-4-dimethylaminoazobenzene or 4-aminoazobenzene.
Topics: Adenoma; Animals; Azo Compounds; Carcinogens; Female; Liver Neoplasms; Lung Neoplasms; Lymphoma; Maternal-Fetal Exchange; Methyldimethylaminoazobenzene; Mice; Mice, Inbred Strains; Neoplasms, Experimental; p-Aminoazobenzene; p-Dimethylaminoazobenzene; Pregnancy; Teratoma | 1983 |
Effect of 3'-methyl-N,N-dimethyl-4-aminoazobenzene in the presence or absence of liver microsomes on the liver cells having low tumor-producing capacity in culture.
Topics: Animals; Cell Transformation, Neoplastic; Cells, Cultured; Liver; Liver Neoplasms; Methyldimethylaminoazobenzene; Microsomes, Liver; Neoplasm Transplantation; p-Dimethylaminoazobenzene; Rats | 1983 |
Uptake and hepatobiliary fate of two hepatocarcinogens, N,N-dimethyl-4-aminoazobenzene and 3'-methyl-N,N-dimethyl-4-aminoazobenzene, in the rat.
Topics: Animals; Bile; Chromatography, High Pressure Liquid; Half-Life; Liver; Male; Methyldimethylaminoazobenzene; p-Dimethylaminoazobenzene; Rats; Rats, Inbred Strains; Tissue Distribution | 1983 |
Effects of inhibiting hepatocarcinogenesis upon the early fine structural changes induced in rat hepatocytes by 3'-methyl-4-dimethylaminoazobenzene.
Topics: Animals; Carcinogens; Liver; Liver Neoplasms, Experimental; Lysosomes; Male; Methylcholanthrene; Methyldimethylaminoazobenzene; Microscopy, Electron; Monoamine Oxidase Inhibitors; p-Dimethylaminoazobenzene; Rats; Rats, Inbred Strains | 1983 |
Inhibitory effect of fumaric acid on 3-methyl-4'-(dimethylamino)-azobenzene-induced hepatocarcinogenesis in rats.
Topics: Animals; Diet; Drug Interactions; Fumarates; Hyperplasia; Liver; Liver Neoplasms; Male; Methyldimethylaminoazobenzene; p-Dimethylaminoazobenzene; Rats | 1983 |
Participation of cytochrome P450 in mutagenic activation of the carcinogen 3'-hydroxymethyl-N,N-dimethyl-4-aminoazobenzene and its N-demethylated compounds by rat liver.
Topics: Animals; Biotransformation; Carcinogens; Cocarcinogenesis; Cytochrome P-450 Enzyme System; Liver; Methyldimethylaminoazobenzene; Mutagenicity Tests; p-Dimethylaminoazobenzene; Rats; Rats, Inbred Strains; Salmonella typhimurium | 1983 |
Immunochemical study on the contributions of two molecular species of cytochrome P-450 in mutagenesis by selected aminoazo dyes.
Topics: Animals; Biotransformation; Coloring Agents; Cytochrome P-450 Enzyme System; Isoenzymes; Male; Methyldimethylaminoazobenzene; Microsomes, Liver; Monoamine Oxidase Inhibitors; Mutagens; Mutation; p-Dimethylaminoazobenzene; Rats; Rats, Inbred Strains; Salmonella typhimurium | 1983 |
NADPH-dependent lipid peroxidation in the liver microsome of rats fed a 3'-methyl-4-dimethyl-aminoazobenzene (3'-Me-DAB)-containing diet.
Topics: Animals; Cytochrome P-450 Enzyme System; Lipid Peroxides; Male; Methyldimethylaminoazobenzene; Microsomes, Liver; NADP; NADPH-Ferrihemoprotein Reductase; p-Dimethylaminoazobenzene; Rats; Rats, Inbred Strains | 1983 |
Chromosomal protein antigens formed in experimental hepatocarcinogenesis by azo dyes.
Topics: Adenocarcinoma; Animals; Antigens, Neoplasm; Carcinogens; Chromosomes; Liver; Liver Neoplasms; Liver Neoplasms, Experimental; Methyldimethylaminoazobenzene; Mice; Nucleoproteins; p-Dimethylaminoazobenzene; Rats | 1983 |
Toxic effects of 2-methyl-4-dimethylaminoazobenzene in normal and partially hepatectomized rats.
Topics: Animals; Body Weight; Diet; Hepatectomy; Lethal Dose 50; Liver; Male; Methyldimethylaminoazobenzene; Mitosis; p-Dimethylaminoazobenzene; Rats; Rats, Inbred Strains | 1984 |
Inhibition of mitochondrial oxidative phosphorylation by 2-methyl-4-dimethylaminoazobenzene.
Topics: Animals; Kinetics; Methyldimethylaminoazobenzene; Mitochondria, Liver; NAD; Oxidation-Reduction; Oxidative Phosphorylation; p-Dimethylaminoazobenzene; Rats; Rotenone; Succinates; Succinic Acid; Ubiquinone | 1984 |
Azoreductase activity of Sprague Dawley and Wistar-derived rats towards both carcinogenic and non-carcinogenic analogues of 4-dimethylaminophenylazobenzene (DAB).
Topics: Age Factors; Animals; Azo Compounds; Benzothiazoles; Carcinogens; Cecum; Diet; Liver; Male; Methyldimethylaminoazobenzene; NADH, NADPH Oxidoreductases; Nitroreductases; p-Dimethylaminoazobenzene; Rats; Rats, Inbred Strains; Species Specificity; Thiazoles | 1984 |
Dietary carbohydrate level as a modifying factor of 3'-methyl-4-dimethylaminoazobenzene liver carcinogenesis in rats.
Topics: Animals; Biotransformation; Body Weight; Dietary Carbohydrates; Liver Neoplasms, Experimental; Male; Methyldimethylaminoazobenzene; Organ Size; p-Dimethylaminoazobenzene; Rats; Rats, Inbred Strains; Riboflavin Deficiency | 1984 |
Changes of aldolase A and B messenger RNA levels in rat liver during azo-dye-induced hepatocarcinogenesis.
Topics: Animals; Fructose-Bisphosphate Aldolase; Isoenzymes; Liver; Liver Neoplasms, Experimental; Male; Methyldimethylaminoazobenzene; Nucleic Acid Hybridization; p-Dimethylaminoazobenzene; Rats; Rats, Inbred Strains; RNA, Messenger; Transcription, Genetic | 1984 |
Functional changes in rat liver mitochondria on administration of 2-methyl-4-dimethylaminoazobenzene.
Topics: Animals; Cholesterol; Cytochromes; Male; Methyldimethylaminoazobenzene; Mitochondria, Liver; Oxidative Phosphorylation; p-Dimethylaminoazobenzene; Proteins; Rats; Submitochondrial Particles; Ubiquinone | 1984 |
Influence of microsomal and cytosolic fractions from the liver of 4 animal species and man on the mutagenicity of carcinogenic aminoazo dyes and nature of the mutagenicity-enhancing factor in the cytosol from rat liver.
Topics: Animals; Biotransformation; Carcinogens; Cricetinae; Cytosol; Female; Humans; Liver; Male; Mesocricetus; Methyldimethylaminoazobenzene; Microsomes, Liver; Mutagens; p-Dimethylaminoazobenzene; Polychlorinated Biphenyls; Rabbits; Rats; Rats, Inbred Strains; Temperature | 1984 |
Inhibition of mitochondrial electron transport and energy transduction by 2-methyl-4-dimethylaminoazobenzene in vitro.
Topics: Animals; Electron Transport; Energy Metabolism; In Vitro Techniques; Male; Methyldimethylaminoazobenzene; Mitochondria, Liver; p-Dimethylaminoazobenzene; Rats; Rats, Inbred Strains | 1984 |
Existence of a practical threshold dose for the hepatocarcinogen 3'-methyl-4-(dimethyl-amino) azobenzene in rat liver.
Topics: Adenosine Triphosphatases; Animals; Liver; Liver Neoplasms, Experimental; Male; Methyldimethylaminoazobenzene; p-Dimethylaminoazobenzene; Precancerous Conditions; Rats; Rats, Inbred Strains | 1981 |
Localization of fetal aldolases during early stages of azo-dye hepatocarcinogenesis in rat.
Topics: Animals; Fluorescent Antibody Technique; Fructose-Bisphosphate Aldolase; Immunoenzyme Techniques; Isoenzymes; Liver; Liver Neoplasms; Male; Methyldimethylaminoazobenzene; Neoplasms, Experimental; p-Dimethylaminoazobenzene; Rats | 1980 |
Effect of retinoic acid, butylated hydroxytoluene, selenium and sorbic acid on azo-dye hepatocarcinogenesis.
Topics: Animals; Drug Interactions; Fatty Acids, Unsaturated; Liver Neoplasms; Male; Methyldimethylaminoazobenzene; Neoplasms, Experimental; p-Dimethylaminoazobenzene; Rats; Selenium; Sorbic Acid; Time Factors; Toluene; Tretinoin | 1980 |
Correlation of deoxycytidylate deaminase activity with cell proliferation during hepatocarcinogenesis and tumour growth in transplantable rat hepatomas.
Topics: Aflatoxins; Animals; Cell Division; DCMP Deaminase; Liver; Liver Neoplasms, Experimental; Methyldimethylaminoazobenzene; Neoplasm Transplantation; Nucleotide Deaminases; p-Dimethylaminoazobenzene; Precancerous Conditions; Rats | 1980 |
Inhibition of chemical carcinogenesis: early increase in tissue uptake and macromolecular binding of [3H]-labelled metabolites of the hepatocarcinogen 3'-methyl-4-dimethylaminoazobenzene in rat liver in vivo in the presence of the tumour inhibitor chloram
Topics: Animals; Chloramphenicol; Drug Interactions; Liver; Liver Neoplasms; Male; Methyldimethylaminoazobenzene; p-Dimethylaminoazobenzene; Rats; Tritium | 1980 |
In vitro incorporation of 3'-methyl-4-dimethylaminoazobenzene into liver nuclei and release of RNA from the nuclei.
Topics: Animals; Cell Nucleus; Cell-Free System; Cytosol; Liver; Methyldimethylaminoazobenzene; p-Dimethylaminoazobenzene; Rats; RNA, Messenger | 1981 |
Binding of 3'-methyl-N,N-dimethyl-4-aminoazobenzene metabolites to rat liver cytosol proteins and ligandin subunits.
Topics: Animals; Cytosol; Electrophoresis, Polyacrylamide Gel; Glutathione Transferase; Injections, Intraperitoneal; Liver; Liver Neoplasms; Male; Methyldimethylaminoazobenzene; p-Dimethylaminoazobenzene; Protein Binding; Proteins; Rats; Time Factors | 1981 |
The effect of phenobarbital and 3'-methyl-N,N-dimethyl-4-aminoazobenzene administration on catalytic, binding and immunological properties of ligandin subunits in rat liver.
Topics: Animals; Bilirubin; Circular Dichroism; Cytosol; Electrophoresis, Polyacrylamide Gel; Glutathione Transferase; Liver; Male; Methyldimethylaminoazobenzene; Molecular Weight; p-Dimethylaminoazobenzene; Phenobarbital; Rats; Steroid Isomerases | 1981 |
Mechanisms of inhibition by simultaneously administered phenobarbital of 3'-methyl-4-(dimethylamino)azobenzene-induced hepatocarcinogenesis in the rat.
Topics: Animals; Carcinogens; Enzyme Induction; Liver; Liver Neoplasms; Male; Methyldimethylaminoazobenzene; p-Dimethylaminoazobenzene; Phenobarbital; Rats | 1980 |
Tumorigenicity of 3'-hydroxymethyl, 3'-formyl, and 3'-carboxy derivatives of 4-(dimethylamino)azobenzene in rat liver.
Topics: Animals; Body Weight; Carcinogens; Diet; Liver; Liver Neoplasms, Experimental; Male; Methyldimethylaminoazobenzene; Organ Size; p-Dimethylaminoazobenzene; Rats; Rats, Inbred Strains | 1981 |
Syntheses of deuterated 3'-hydroxymethyl-4-(dimethylamino)-azobenzene and related compound.
Topics: Carcinogens; Deuterium; Isotope Labeling; Methyldimethylaminoazobenzene; p-Dimethylaminoazobenzene | 1981 |
The effects of pre-incubation period and norharman on the mutagenic potency of 4-dimethylaminoazobenzene and 3'-methyl-4-dimethylaminoazobenzene in S. typhimurium.
Topics: Alkaloids; Animals; Carbolines; Harmine; In Vitro Techniques; Male; Methyldimethylaminoazobenzene; Mutagens; p-Dimethylaminoazobenzene; Rats; Rats, Inbred Strains; Salmonella typhimurium; Subcellular Fractions; Time Factors | 1981 |
Preferential inhibition of the B-form of monoamine oxidase in the liver of rats given 3'-methyl-4-dimethylaminoazobenzene in the diet.
Topics: Animals; Clorgyline; Diet; Kinetics; Male; Methyldimethylaminoazobenzene; Mitochondria, Liver; Monoamine Oxidase; Monoamine Oxidase Inhibitors; p-Dimethylaminoazobenzene; Pargyline; Rats; Selegiline | 1982 |
Induction of drug-metabolizing enzymes in the rat liver by 3'-methyl-4-(dimethylamino)azobenzene.
Topics: Animals; Cell Fractionation; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Enzyme Induction; Liver; Male; Methylcholanthrene; Methyldimethylaminoazobenzene; Microsomes, Liver; Mutagenicity Tests; p-Dimethylaminoazobenzene; Rats | 1982 |
Inhibition of monoamine oxidase by 3'-methyl-4-dimethylamino azobenzene (3'-me-DAB) in rat liver mitochondria.
Topics: Animals; Kinetics; Male; Methyldimethylaminoazobenzene; Mitochondria, Liver; Monoamine Oxidase Inhibitors; p-Dimethylaminoazobenzene; Pargyline; Rats; Rats, Inbred Strains | 1982 |
Participation of the microsomal electron transport system in mutagenic activation of 4-dimethylaminoazobenzene, 4-methylaminoazobenzene and their 3'-methyl-derivatives.
Topics: Animals; Azo Compounds; Biotransformation; Carcinogens; Drug Evaluation, Preclinical; Electron Transport; Kinetics; Male; Methyldimethylaminoazobenzene; Microsomes, Liver; Mutagens; NADPH-Ferrihemoprotein Reductase; p-Aminoazobenzene; p-Dimethylaminoazobenzene; Rats; Rats, Inbred Strains; Salmonella typhimurium | 1982 |
[Changes of 67Ga-citrate accumulation in the rat liver during feeding with chemical carcinogen 3'-methyl-4-dimethylaminoazobenzene (author's transl)].
Topics: Animals; Gallium Radioisotopes; Liver; Liver Neoplasms; Male; Methyldimethylaminoazobenzene; Neoplasms, Experimental; p-Dimethylaminoazobenzene; Rats; Time Factors | 1982 |
Elevation of serum albumin concentration in analbuminemic rats by administration of 3'-methyl-4-dimethylaminoazobenzene.
Topics: Animals; Blood Protein Electrophoresis; Blood Proteins; Chemical Phenomena; Chemistry; Methyldimethylaminoazobenzene; p-Dimethylaminoazobenzene; Peptides; Rats; Rats, Inbred Strains; Serum Albumin; Stimulation, Chemical | 1982 |
A comparative study of ultrastructural changes induced by chronic treatment with 3'-methyl-4-dimethylaminoazobenzene and the non-carcinogen 3'-methyl-4-diethylaminoazobenzene in the rat hepatocyte.
Topics: Animals; Diet; Liver; Liver Neoplasms; Male; Methyldimethylaminoazobenzene; Neoplasms, Experimental; p-Dimethylaminoazobenzene; Rats; Rats, Inbred Strains | 1982 |
N-Hydroxylation enzymes of carcinogenic aminoazo dyes: possible involvement of cytochrome P-448.
Topics: Animals; Azo Compounds; Cytochrome P-450 CYP1A2; Cytochromes; Free Radicals; Hydroxylation; Male; Methyldimethylaminoazobenzene; Microsomes, Liver; NAD; NADP; Oxidoreductases Acting on CH-NH Group Donors; p-Aminoazobenzene; p-Dimethylaminoazobenzene; Rats; Rats, Inbred Strains | 1982 |
Effect of 3'-methyl-4-dimethylaminoazobenzene in the induction of malignant transformation and of 8-azaguanine-resistant mutations and chromosomal aberrations in a diploid clone derived from normal rat liver cells in culture.
Topics: Animals; Azaguanine; Cell Transformation, Neoplastic; Chromosome Aberrations; Clone Cells; Drug Resistance; Liver; Liver Neoplasms; Methyldimethylaminoazobenzene; Neoplasms, Experimental; p-Dimethylaminoazobenzene; Rats | 1982 |
3-Methylcholanthrene-inhibition of hepatocarcinogenesis in the rat due to 3'-methyl-4-dimethylaminoazobenzene or 2-acetylamino-fluorene: a comparative study.
Topics: 2-Acetylaminofluorene; Animals; Liver Neoplasms; Liver Neoplasms, Experimental; Male; Methylcholanthrene; Methyldimethylaminoazobenzene; p-Dimethylaminoazobenzene; Rats | 1982 |
[Distribution of 67Ga-citrate in 3'-methyl-4-dimethylaminoazobenzene-induced hepatoma of rats].
Topics: Animals; Autoradiography; Gallium Radioisotopes; Liver Neoplasms; Liver Neoplasms, Experimental; Male; Methyldimethylaminoazobenzene; p-Dimethylaminoazobenzene; Rats; Rats, Inbred Strains | 1982 |
Decreased viscosity of rat-liver DNA treated by 3'-methyl-4-dimethylaminoazobenzene, detected with a new viscometric approach.
Topics: Animals; DNA; Liver; Male; Methods; Methyldimethylaminoazobenzene; p-Dimethylaminoazobenzene; Rats; Rats, Inbred Strains; Viscosity | 1982 |
Effect of 3'-methyl-4-dimethylaminoazobenzene on arginine metabolism in rat liver.
Topics: Animals; Arginine; Carcinogens; Liver; Methyldimethylaminoazobenzene; p-Dimethylaminoazobenzene; Rats | 1982 |
Quantitative morphological studies on the livers and liver homogenates of rats fed 2-methyl- or 3 -methyl-4-dimethylaminoazobenzene.
Topics: Animals; Coloring Agents; Liver; Methyldimethylaminoazobenzene; p-Dimethylaminoazobenzene; Rats | 1953 |
Enzymatic and chemical studies on the livers and liver mitochondria of rats fed 2-methyl- or 3-methyl-4-dimethylaminoazobenzene.
Topics: Animals; Coloring Agents; Liver; Methyldimethylaminoazobenzene; Mitochondria; Mitochondria, Liver; p-Dimethylaminoazobenzene; Rats | 1953 |
[Influencing the nitrogen fractions of rat serum by short-interval feeding of 3'methyl-4-dimethylaminoazobenzene].
Topics: Animals; Benzene; Benzene Derivatives; Blood; Methyldimethylaminoazobenzene; Nitrogen; p-Dimethylaminoazobenzene; Rats | 1953 |
Studies on hepatic protein-bound dye formation in rats given single large doses of 3'methyl-4-dimethylaminoazobenzene.
Topics: Animals; Coloring Agents; Liver; Methyldimethylaminoazobenzene; p-Dimethylaminoazobenzene; Protein Biosynthesis; Rats | 1958 |
Fine structural alterations in cell particles during chemical carcinogenesis. III. Selective action of hepatic carcinogens other than 3'-methyl-4-dimethylaminoazobenzene on different types of mitochondrial swelling. Effect of stimulated liver growth.
Topics: Animals; Carcinogenesis; Carcinogens; Guinea Pigs; Liver; Methylcholanthrene; Methyldimethylaminoazobenzene; Mitochondria; Mitochondria, Liver; Mitochondrial Swelling; p-Aminoazobenzene; p-Dimethylaminoazobenzene; Rats; Thyroxine | 1961 |
[Influence of fatty acids on carcinogenesis. I. Influence of fatty acids on carcinogenesis in the rat induced by 3-methyl-4-dimethylaminoazobenzene].
Topics: Animals; Azo Compounds; Carcinogenesis; Fatty Acids; Methyldimethylaminoazobenzene; p-Dimethylaminoazobenzene; Rats | 1961 |
Fine stuctural alterations in cell particles during chemical carcinogenesis. II. Further evidence for their involvement in the mechanism of carcinogenesis. The swelling of rat liver mitochondria during feeding of amino azo dyes.
Topics: Animals; Azo Compounds; Carcinogenesis; Carcinogens; Carcinoma, Hepatocellular; Coloring Agents; Liver; Liver Neoplasms; Methyldimethylaminoazobenzene; Mitochondria; Mitochondria, Liver; Mitochondrial Swelling; p-Dimethylaminoazobenzene; Rats | 1960 |
The effect of the carcinogen 3'-methyl-4-dimethylaminoazobenzene on protein synthesis by rat-liver microsomes.
Topics: Animals; Azo Compounds; Carcinogens; Liver; Methyldimethylaminoazobenzene; Microsomes; Microsomes, Liver; p-Dimethylaminoazobenzene; Protein Biosynthesis; Proteins; Rats | 1962 |
Comparative studies on the transplantability of liver cancers induced in rats fed with 3'-methyl-4-dimethylaminoazobenzene for 3-6 months.
Topics: Animals; Bile Duct Neoplasms; Bile Ducts, Intrahepatic; Liver Neoplasms; Methyldimethylaminoazobenzene; p-Dimethylaminoazobenzene; Rats | 1962 |
[CHANGES IN ULTRASTRUCTURES OF RAT LIVER CELLS DURING AZO DYE CARCINOGENESIS. III. CHANGES OF RAT LIVER CELLS IN PRECANCEROUS STAGE OF 3-METHYL-4-DIMETHYLAMINOAZOBENZENE FEEDING].
Topics: Azo Compounds; Carcinogenesis; Coloring Agents; Electrons; Hepatocytes; Liver; Liver Neoplasms; Methyldimethylaminoazobenzene; Microscopy; Microscopy, Electron; p-Dimethylaminoazobenzene; Physiology; Rats; Research | 1963 |
THE EFFECT OF 3'-METHYL-4-DIMETHYLAMINOAZOBENZENE ON PROTEIN SYNTHESIS AND DNA-DEPENDENT RNA-POLYMERASE ACTIVITY IN RAT-LIVER NUCLEI.
Topics: Carbon Isotopes; Cell Nucleus; DNA; Leucine; Liver; Methyldimethylaminoazobenzene; Nucleotidases; p-Dimethylaminoazobenzene; Pharmacology; Protein Biosynthesis; Proteins; Rats; Research; RNA | 1964 |
THE EFFECT OF SHORT-TERM FEEDING EXPERIMENTS WITH 3'-METHYL-4-DIMETHYLAMINOAZOBENZENE OF RAT-LIVER MITOCHONDRIAL FUNCTION.
Topics: Carcinoma, Hepatocellular; Citrates; Citric Acid Cycle; Glutamates; Hydroxybutyrates; Isocitrate Dehydrogenase; Ketoglutaric Acids; Liver; Liver Neoplasms; Malate Dehydrogenase; Metabolism; Methyldimethylaminoazobenzene; Microsomes; Mitochondria; N-Glycosyl Hydrolases; NAD; NADP; Niacinamide; Ornithine; Ornithine Carbamoyltransferase; Oxidoreductases; p-Dimethylaminoazobenzene; Rats; Research; Succinate Dehydrogenase; Toxicology | 1964 |
[CHARACTERISTICS IN THE METABOLIC CHANGES OF THE LIVER OF RATS IN THE EARLY STAGES OF 3'-METHYL-4-DIMETHYLAMINOAZOBENZENE ADMINISTRATION. I. INFLUENCES OF THE DOSAGE OF THE DYE AND THE ROUTE OF ADMINISTRATION UPON THE CHANGES OF LIVER].
Topics: Coloring Agents; DNA; Electron Transport Complex II; Electron Transport Complex IV; Liver; Metabolism; Methyldimethylaminoazobenzene; p-Dimethylaminoazobenzene; Rats; Research; RNA; Succinate Dehydrogenase | 1963 |
[CHARACTERISTICS IN THE METABOLIC CHANGES OF THE LIVER OF RATS IN THE EARLY STAGES OF 3'-METHYL-4-DIMETHYLAMINOAZOBENZENE ADMINISTRATION. II. CHANGES IN SUBCELLULAR PARTICLES OF RAT LIVER INDUCED BY 3'-METHYL-4-DIMETHYLAMINOAZOBENZENE FEEDING].
Topics: Coloring Agents; DNA; Electrons; Liver; Metabolism; Methyldimethylaminoazobenzene; Microscopy; Microscopy, Electron; Mitochondria; p-Dimethylaminoazobenzene; Rats; Research; RNA | 1963 |
HISTOCHEMICAL STUDIES OF CHOLESTEROL IN THE SUPRARENAL CORTEX OF RATS IN LIVER CANCEROGENESIS INDUCED BY 3-METHYL 4-DIMETHYLAMINOAZOBENZENE.
Topics: Adrenal Glands; Cholesterol; Histocytochemistry; Lipid Metabolism; Liver Neoplasms; Methyldimethylaminoazobenzene; Neoplasms; Neoplasms, Experimental; p-Dimethylaminoazobenzene; Pathology; Rats; Research | 1964 |
ANALYSIS OF THE LIVERS AND TUMORS FOR FOURTEEN TRACE ELEMENTS OF RATS FED 3'-METHYL-4-DIMETHYLAMINOAZOBENZENE (3'-ME-DAB).
Topics: Carcinoma; Carcinoma, Hepatocellular; Copper; Dietary Proteins; Histocytochemistry; Iron; Liver; Liver Neoplasms; Manganese; Methyldimethylaminoazobenzene; Molybdenum; NADP; Neoplasms, Experimental; Nickel; p-Dimethylaminoazobenzene; Pharmacology; Phosphorus; Phosphorus, Dietary; Rats; Research; Trace Elements; Vitamin B Deficiency; Zinc | 1964 |
DIFFERENT BIOLOGICAL CHARACTERISTICS OF LIVER CANCERS OF A SINGLE RAT INDUCED BY 3'-METHYL-4-DIMETHYLAMINOAZOBENZENE, AS REVEALED BY COMPARATIVE STUDIES OF THEIR ASCITIC FORMS.
Topics: Animals; Bile Duct Neoplasms; Bile Ducts, Intrahepatic; Chromosomes; Karyometry; Liver Neoplasms; Mechlorethamine; Methyldimethylaminoazobenzene; p-Dimethylaminoazobenzene; Pathology; Rats; Research; Toxicology | 1964 |
The effect of feeding 3'-methyl-4-dimethylaminoazobenzene on tryptophan metabolism of rats.
Topics: Animals; Carcinogens; Liver; Liver Neoplasms, Experimental; Methyldimethylaminoazobenzene; p-Dimethylaminoazobenzene; Rats; Tryptophan | 1961 |
Effect of copper on hepatic tumors produced by 3-methyl-4-dimethylaminoazobenzene.
Topics: Copper; Liver Neoplasms; Methyldimethylaminoazobenzene; p-Dimethylaminoazobenzene | 1951 |
A sex difference in the development of liver tumors in rats fed 3'-methyl-4-dimethylaminoazobenzene or 4'-fluoro-4-dimethylaminoazobenzene.
Topics: Animals; Carcinogens; Liver Neoplasms; Methyldimethylaminoazobenzene; p-Dimethylaminoazobenzene; Rats; Sex Characteristics | 1951 |
Progressive microscopic alterations in the livers of rats fed the hepatic carcinogens 3'-methyl-4-dimethylaminoazobenzene and 4'-fluoro-4-dimethylaminoazobenzene.
Topics: Animals; Carcinogens; Liver; Methyldimethylaminoazobenzene; p-Dimethylaminoazobenzene; Rats | 1952 |
Studies on the intracellular composition of livers from rats fed various aminoazo dyes; 3'-methyl-,2'-methyl-, and 2-methyl-4-dimethylaminoazobenzene,3-methyl-4-monomethylaminoazobenzene, and 4'-fluoro-4-dimethylaminoazobenzene.
Topics: Animals; Coloring Agents; Cytoplasm; Liver; Methyldimethylaminoazobenzene; p-Dimethylaminoazobenzene; Rats | 1950 |
Species-specific effects of the hepatocarcinogens 3'-methyl-4-dimethyl-aminoazobenzene and ortho-aminoazotoluene in mouse and rat liver.
Topics: Animals; Carcinogens; Cell Nucleus; Diethylnitrosamine; Enzyme Induction; Glucocorticoids; Hepatocyte Nuclear Factor 3-alpha; Liver; Liver Neoplasms, Experimental; Male; Methyldimethylaminoazobenzene; Mice; o-Aminoazotoluene; p-Dimethylaminoazobenzene; Rats; Rats, Wistar; RNA, Messenger; Species Specificity; Tyrosine Transaminase | 2005 |