methyldeoxyspergualin has been researched along with tacrolimus in 5 studies
| Studies (methyldeoxyspergualin) | Trials (methyldeoxyspergualin) | Recent Studies (post-2010) (methyldeoxyspergualin) | Studies (tacrolimus) | Trials (tacrolimus) | Recent Studies (post-2010) (tacrolimus) |
|---|---|---|---|---|---|
| 29 | 0 | 2 | 17,757 | 2,319 | 6,661 |
| Protein | Taxonomy | methyldeoxyspergualin (IC50) | tacrolimus (IC50) |
|---|---|---|---|
| Bile salt export pump | Homo sapiens (human) | 7.18 | |
| Cytochrome P450 3A4 | Homo sapiens (human) | 0.58 | |
| Cytochrome P450 3A5 | Homo sapiens (human) | 0.385 | |
| Serine/threonine-protein kinase mTOR | Homo sapiens (human) | 0.0021 | |
| Peptidyl-prolyl cis-trans isomerase FKBP1A | Homo sapiens (human) | 0.2547 | |
| Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform | Homo sapiens (human) | 0.0148 | |
| Splicing factor 3B subunit 3 | Homo sapiens (human) | 0.0123 | |
| Broad substrate specificity ATP-binding cassette transporter ABCG2 | Homo sapiens (human) | 3.3 | |
| Solute carrier organic anion transporter family member 1B1 | Homo sapiens (human) | 3.7 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 5 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ishibashi, M; Jiang, H; Kokado, Y; Okuyama, A; Sonoda, T; Takahara, S; Takano, Y | 1 |
| Ishibashi, M; Jiang, H; Kameoka, H; Kokado, Y; Li, D; Moutabarrik, A; Okuyama, A; Suguo, H; Takahara, S; Takano, Y | 1 |
| Fukuzawa, M; Ito, T; Izutani, H; Matsuda, H; Matsumiya, G; Miyagawa, S; Nakata, S; Nozaki, T; Shirakura, R; Yamamoto, S | 1 |
| Fukao, K; Otsuka, M; Yu, Y; Yuzawa, K | 1 |
| Deol, HS; Tuch, BE; Wright, DC | 1 |
5 other study(ies) available for methyldeoxyspergualin and tacrolimus
| Article | Year |
|---|---|
The in vitro immunosuppressive effect of deoxymethylspergualin in man as compared with FK506 and cyclosporine.
Topics: Cyclosporine; Cytotoxicity, Immunologic; Guanidines; Humans; Immunosuppressive Agents; Lymphocyte Activation; Lymphocyte Culture Test, Mixed; Receptors, Interleukin-2; Tacrolimus | 1992 |
Combined immunosuppressive effect of FK 506 and other immunosuppressive agents on PHA- and CD3-stimulated human lymphocyte proliferation in vitro.
Topics: Antigens, Differentiation, T-Lymphocyte; Azathioprine; CD3 Complex; Cells, Cultured; Cyclosporine; DNA Replication; Drug Interactions; Guanidines; Humans; Immunosuppressive Agents; Lymphocyte Activation; Lymphocytes; Phytohemagglutinins; Receptors, Antigen, T-Cell; Ribonucleosides; Tacrolimus | 1991 |
Immunosuppressive mechanisms of deoxymethylspergualin and FK 506 on in vitro cytotoxic T lymphocytes.
Topics: Animals; Cells, Cultured; Cytotoxicity, Immunologic; Guanidines; Heart Transplantation; Humans; Immunosuppressive Agents; Interferon-gamma; Interleukin-1; Interleukin-2; Rats; Rats, Inbred BUF; Rats, Inbred Lew; Recombinant Proteins; Skin Transplantation; T-Lymphocytes, Cytotoxic; Tacrolimus; Transplantation, Homologous | 1994 |
Mutagenicity of the new immunosuppressive drugs, FK 506, and spergualin.
Topics: Adult; Cells, Cultured; Dose-Response Relationship, Drug; Female; Guanidines; Humans; Immunosuppressive Agents; Lymphocytes; Male; Mutagenicity Tests; Mutagens; Sister Chromatid Exchange; Tacrolimus | 1993 |
A comparison of the sensitivity of pig and human peripheral blood mononuclear cells to the antiproliferative effects of traditional and newer immunosuppressive agents.
Topics: Animals; Azathioprine; Cell Division; Cyclosporine; Diabetes Mellitus, Type 1; Graft Rejection; Guanidines; Humans; Immunosuppressive Agents; In Vitro Techniques; Islets of Langerhans Transplantation; Leukocytes, Mononuclear; Lymphocyte Activation; Lymphocyte Culture Test, Mixed; Methylprednisolone; Mycophenolic Acid; Phytohemagglutinins; Sirolimus; Species Specificity; Swine; Tacrolimus; Transplantation, Homologous | 1999 |