methylbenzoprim has been researched along with trimetrexate in 4 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (75.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lambert, PA; O'Shea, DM; Phillip, KS; Queener, SF; Rathbone, DL; Schwalbe, CH; Stevens, MF | 1 |
| Griffin, RJ; Grunwaldt, JD; Lambert, PA; Meek, MA; Queener, SF; Robson, C; Schmidt, D | 1 |
| Croughton, KA; Matthews, CS; Richardson, ML; Stevens, MF | 1 |
| Griffin, RJ; Lambert, PA; Robson, C; Twentyman, PR; Wright, KA | 1 |
4 other study(ies) available for methylbenzoprim and trimetrexate
| Article | Year |
|---|---|
Structural studies on bioactive compounds. 28. Selective activity of triazenyl-substituted pyrimethamine derivatives against Pneumocystis carinii dihydrofolate reductase.
Topics: Animals; Chemical Phenomena; Chemistry, Physical; Crystallization; Crystallography, X-Ray; Folic Acid Antagonists; Liver; Models, Molecular; Molecular Structure; Pneumocystis; Pyrimidines; Rats; Solubility; Tetrahydrofolate Dehydrogenase; Triazenes | 1997 |
Nonclassical 2,4-diamino-5-aryl-6-ethylpyrimidine antifolates: activity as inhibitors of dihydrofolate reductase from Pneumocystis carinii and Toxoplasma gondii and as antitumor agents.
Topics: Animals; Antineoplastic Agents; Cell Survival; Folic Acid Antagonists; Indicators and Reagents; Kinetics; Liver; Lymphoma, Large B-Cell, Diffuse; Mice; Pneumocystis; Pyrimidines; Rats; Structure-Activity Relationship; Tetrahydrofolate Dehydrogenase; Toxoplasma | 1997 |
Structural studies on bioactive compounds. 39. Biological consequences of the structural modification of DHFR-inhibitory 2,4-diamino-6-(4-substituted benzylamino-3-nitrophenyl)-6-ethylpyrimidines ('benzoprims').
Topics: Antineoplastic Agents; Benzylamines; Cell Division; Cell Line, Tumor; Cyclization; Drug Screening Assays, Antitumor; Folic Acid Antagonists; Humans; Protein Binding; Pyrimidines; Structure-Activity Relationship; Tetrahydrofolate Dehydrogenase | 2004 |
Chemical synthesis and biological properties of novel fluorescent antifolates in Pgp- and MRP-overexpressing tumour cell lines.
Topics: 4-Chloro-7-nitrobenzofurazan; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP-Binding Cassette Transporters; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Dansyl Compounds; Drug Screening Assays, Antitumor; Fluorescent Dyes; Folic Acid Antagonists; Growth Inhibitors; Humans; Lung Neoplasms; Multidrug Resistance-Associated Proteins; Pyrimidines; Tetrahydrofolate Dehydrogenase; Trimetrexate; Tumor Cells, Cultured; Umbelliferones | 1998 |