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methylacetylphosphonate and 2,3-diphosphoglycerate

methylacetylphosphonate has been researched along with 2,3-diphosphoglycerate in 4 studies

*2,3-Diphosphoglycerate: A highly anionic organic phosphate which is present in human red blood cells at about the same molar ratio as hemoglobin. It binds to deoxyhemoglobin but not the oxygenated form, therefore diminishing the oxygen affinity of hemoglobin. This is essential in enabling hemoglobin to unload oxygen in tissue capillaries. It is also an intermediate in the conversion of 3-phosphoglycerate to 2-phosphoglycerate by phosphoglycerate mutase (EC 5.4.2.1). (From Stryer Biochemistry, 4th ed, p160; Enzyme Nomenclature, 1992, p508) [MeSH]

*2,3-Diphosphoglycerate: A highly anionic organic phosphate which is present in human red blood cells at about the same molar ratio as hemoglobin. It binds to deoxyhemoglobin but not the oxygenated form, therefore diminishing the oxygen affinity of hemoglobin. This is essential in enabling hemoglobin to unload oxygen in tissue capillaries. It is also an intermediate in the conversion of 3-phosphoglycerate to 2-phosphoglycerate by phosphoglycerate mutase (EC 5.4.2.1). (From Stryer Biochemistry, 4th ed, p160; Enzyme Nomenclature, 1992, p508) [MeSH]

Compound Research Comparison

Studies
(methylacetylphosphonate)
Trials
(methylacetylphosphonate)
Recent Studies (post-2010)
(methylacetylphosphonate)
Studies
(2,3-diphosphoglycerate)
Trials
(2,3-diphosphoglycerate)
Recent Studies (post-2010) (2,3-diphosphoglycerate)
19031,41839117

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19903 (75.00)18.7374
1990's1 (25.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Manning, JM; Ueno, H1
Benjamin, LJ; Manning, JM; Pospischil, MA; Ueno, H1
Kluger, R; Manning, JM; Pospischil, MA; Ueno, H1
Labotka, RJ; London, RE; Xu, AS1

Other Studies

4 other study(ies) available for methylacetylphosphonate and 2,3-diphosphoglycerate

ArticleYear
Methyl acetyl phosphate, a new type of antisickling agent: site-specific acetylating agent toward the 2,3-DPG binding site in hemoglobin S.
    The American journal of pediatric hematology/oncology, 1988,Winter, Volume: 10, Issue:4

    Topics: 2,3-Diphosphoglycerate; Acetylation; Antisickling Agents; Binding Sites; Diphosphoglyceric Acids; Hemoglobin, Sickle; Humans; Organophosphorus Compounds; Phosphonoacetic Acid

1988
Inhibition of the gelation of extracellular and intracellular hemoglobin S by selective acetylation with methyl acetyl phosphate.
    Biochemistry, 1987, Jun-02, Volume: 26, Issue:11

    Topics: 2,3-Diphosphoglycerate; Acetylation; Chromatography, High Pressure Liquid; Diphosphoglyceric Acids; Gels; Hemoglobin, Sickle; Humans; Kinetics; Organophosphorus Compounds; Phosphonoacetic Acid; Protein Conformation

1987
Methyl acetyl phosphate: a novel acetylating agent. Its site-specific modification of human hemoglobin A.
    Journal of chromatography, 1986, May-30, Volume: 359

    Topics: 2,3-Diphosphoglycerate; Alkylating Agents; Amino Acids; Chromatography, High Pressure Liquid; Diphosphoglyceric Acids; Hemoglobin A; Humans; Hydrolysis; Organophosphorus Compounds; Peptides; Phosphonoacetic Acid; Trypsin

1986
Acetylation of human hemoglobin by methyl acetylphosphate. Evidence of broad regio-selectivity revealed by NMR studies.
    The Journal of biological chemistry, 1999, Sep-17, Volume: 274, Issue:38

    Topics: 2,3-Diphosphoglycerate; Acetylation; Antisickling Agents; Aspirin; Binding Sites; Hemoglobins; Humans; Magnetic Resonance Spectroscopy; Phosphonoacetic Acid

1999