methyl methanethiosulfonate has been researched along with methyl methanesulfonate in 123 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 31 (25.20) | 18.7374 |
| 1990's | 54 (43.90) | 18.2507 |
| 2000's | 22 (17.89) | 29.6817 |
| 2010's | 15 (12.20) | 24.3611 |
| 2020's | 1 (0.81) | 2.80 |
| Authors | Studies |
|---|---|
| Hatanaka, Y; Hikichi, K; Ishibashi, T; Kumazaki, T; Nishi, S; Nishihira, J; Sakai, M; Tsuda, S | 1 |
| Chakraborti, PK; Garabedian, MJ; Simons, SS; Yamamoto, KR | 1 |
| Cavanaugh, AH; Simons, SS | 2 |
| Miller, CS; Smith, KO | 1 |
| Claiborne, A; Miller, H | 1 |
| Atkinson, T; Gore, MG; Scawen, MD; Spencer, P | 1 |
| Massey, V; Taylor, MG | 1 |
| Chakraborti, PK; Groner, B; Hoeck, W; Simons, SS | 1 |
| Lauf, PK; Ryu, KH | 1 |
| Hutchison, KA; Matić, G; Meshinchi, S; Pratt, WB | 1 |
| Hummel, BC; Takagi, S; Walfish, PG | 1 |
| Pardo, JP; Slayman, CW | 1 |
| Beinert, H; Emptage, MH; Kennedy, MC; Spoto, G | 1 |
| Lowe, DM; Tubbs, PK | 1 |
| Van Etten, RL; Waheed, A | 1 |
| Bloxham, DP; Salam, WH | 1 |
| Alvear, M; Cardemil, E; Jabalquinto, AM | 1 |
| Jonsson, BH; Lindskog, S; Millqvist, E; Ren, X | 1 |
| Anderson, PM; Fuchs, JA; Johnson, WV; Korte, JJ; Sung, YC; Xiong, XF | 1 |
| Daly, TJ; Matthews, KS; Olson, JS | 1 |
| Daly, TJ; Matthews, KS | 2 |
| Chung, H; Fried, J; Jarabak, J | 1 |
| Grippo, JF; Holmgren, A; Meshinchi, S; Pratt, SE; Pratt, WB; Sanchez, ER; Tienrungroj, W | 1 |
| Grippo, JF; Holmgren, A; Pratt, SE; Pratt, WB; Tienrungroj, W | 1 |
| Ballou, DP; Lewis, SD; Olson, ST; Roberts, DD; Shafer, JA | 1 |
| Egan, RW; Gale, PH | 1 |
| Kitson, TM; Loomes, KM | 1 |
| Smith, S; Witkowski, A | 1 |
| Aranda, G; Cornu, A; Dorange, JL; Dulieu, H | 1 |
| De Bruyne, CK; Kersters-Hilderson, H; Lippens, M; Van Doorslaer, E | 1 |
| Babior, BM; Kopczynski, MG | 1 |
| Goldstein, DJ; Marston, AW; Wright, HT | 1 |
| Hopff, WH; Riggio, G; Waser, PG | 1 |
| Chen, NT; DeHaven, PA; Jaffe, EK; Salowe, SP | 1 |
| Franson, RC; Kyger, EM | 1 |
| Paglia, DE; Valentine, WN | 2 |
| Lewis, SD; Misra, DC; Shafer, JA | 1 |
| Gavilanes, F; Peterson, D; Schirch, L | 1 |
| Bloxham, DP | 1 |
| Kluger, R; Tsui, WC | 1 |
| Adragna, NC; Lauf, PK | 1 |
| Jensen, PE; Shanbhag, VP; Stigbrand, T | 4 |
| Guerra, G; Pardo, JP; Uribe, S | 1 |
| Blättler, WA; Collinson, AR; Singh, R | 1 |
| Pratt, WB; Simons, SS | 1 |
| Hara, A; Hirose, Y; Kawamori, T; Mori, H; Nakamura, Y; Ohnishi, M; Satoh, K; Tanaka, T | 1 |
| Chlumsky, LJ; Jorns, MS; Ramsey, AJ; Zhang, L | 1 |
| Hendrickson, TL; Imperiali, B; Pathak, R | 1 |
| Cane, DE; Fitzsimons, BC; Hohn, TM; Shim, JH; Xue, Q | 1 |
| Cavanaugh, AH; Chakraborti, PK; Modarress, KJ; Simons, SS | 1 |
| Hou, LX; Vollmer, S | 1 |
| Matsuo, T; Nakamura, Y; Shimoi, K; Tomita, I | 1 |
| Harris, KA; Jaffe, EK; Markham, GD; Myers, CB; Volin, M | 1 |
| Kimura, T; Sawai, T; Yamaguchi, A | 1 |
| Aumelas, A; Borgna, JL; el Garrouj, D | 1 |
| Chakraborti, PK; Hutchison, KA; Pratt, WB; Simons, SS; Stancato, LF | 1 |
| Couette, B; Fagart, J; Rafestin-Oblin, ME; Souque, A | 1 |
| Bagui, TK; Datta, AK; Ghosh, M | 1 |
| Patel, MA; Salleh, HM; Woodard, RW | 1 |
| Caine, JM; Grunewald, GL; Macreadie, IG; McLeish, MJ | 1 |
| Matsuo, T; Nakamura, Y; Nakamura, YK; Shimoi, K; Tomita, I | 1 |
| Ehrlich, BE; Quinn, KE | 1 |
| Kawamori, T; Makita, H; Mori, H; Nakamura, Y; Nakamura, YK; Ohnishi, M; Okamoto, K; Sugie, S; Tanaka, T; Tomita, I; Watanabe, T | 1 |
| Becker, I; Berzunza, M; Garza-Ramos, G; Gómez-Puyou, A; Landa, A; Ostoa-Saloma, P; Pérez-Montfort, R; Ramírez, J; Tuena de Gómez-Puyou, M | 1 |
| Desoye, G; Nöhammer, G | 1 |
| Kawabata, K; Matsunaga, K; Mori, H; Morishita, Y; Sugie, S; Tanaka, T; Yoshimi, N | 1 |
| Furukawa, H; Kawai, K; Matsuo, T; Nakamura, Y; Nakamura, YK; Shimoi, K; Tomita, I | 1 |
| Ito, Y; Nakamura, Y | 1 |
| Goulding, CW; Matthews, RG | 1 |
| Brown, AM; Kirsch, GE; Pascual, JM; Shieh, CC | 1 |
| Kimura, T; Sawai, T; Shiina, Y; Yamaguchi, A | 1 |
| Ikeda, Y; Noguchi, T | 1 |
| Ha, JH; Loh, SN | 1 |
| Cabrera, N; de Gómez-Puyou, M; Garza-Ramos, G; Gómez-Puyou, A; Maldonado, E; Moreno, A; Perez-Montfort, R; Soriano-García, M | 1 |
| Barnes, MH; Brown, NC; Leo, CJ | 1 |
| Cavanaugh, AH; Edwards, DP; Modarress, KJ; Plisov, SY; Poirot, ME; Simons, SS | 1 |
| Alcántara, GH; de Gómez-Puyou, MT; Gao, XG; Garza-Ramos, G; Gómez-Puyou, A; Maldonado, E; Pérez-Montfort, R; Reyes-Vivas, H | 1 |
| Fitzpatrick, FA; Orning, L | 1 |
| Massey, V; Sanders, SA; Williams, CH | 1 |
| Aliau, S; Borgna, JL; Delettre, G; El Garrouj, D; Mattras, H; Nique, F; Teutsch, G | 1 |
| Goto, S; Hashimoto, M; Hatanaka, T; Majima, E; Onishi, M; Shinohara, Y; Terada, H | 1 |
| Bravo, DT; Keller, JE; Parsons, SM | 1 |
| Biber, J; Forster, IC; Lambert, G; Murer, H | 1 |
| Briggs, WH; Goldman, IL; Parkin, KL; Shen, C; Xiao, H | 1 |
| Loussouarn, G; Masia, R; Nichols, CG; Phillips, LR; Rose, T | 1 |
| Aliaga, C; Cohen, LA; Lubet, R; Pittman, B; Zhao, Z | 1 |
| Alam, SL; Butler, MC; Feng, Z; Loh, SN | 1 |
| Andricopulo, AD; Arscott, LD; Becker, K; Davioud-Charvet, E; Giegel, D; Kenyon, GL; McLeish, MJ; Müller, S; Schirmer, RH; Veine, DM; Williams, CH | 1 |
| Kurbannazarova, RS; Sabirov, RZ; Tashmukhamedov, BA | 1 |
| Britto, PJ; Knipling, L; McPhie, P; Wolff, J | 1 |
| Garrow, TA; Miller, CM; Szegedi, SS | 1 |
| Afzal, M; Siddique, YH | 1 |
| González-Segura, L; Mújica-Jiménez, C; Muñoz-Clares, RA; Velasco-García, R; Zaldívar-Machorro, VJ | 1 |
| Hynson, RM; Mathews, FS; Schuman Jorns, M | 1 |
| Aguirre-López, B; de Gómez-Puyou, MT; Gómez-Puyou, A; Hernández-Alcántara, G; Pérez-Montfort, R; Zomosa-Signoret, V | 1 |
| Karala, AR; Ruddock, LW | 1 |
| Au, WW; Henderson, BR | 1 |
| Bhattacharyya, J; Enkvetchakul, D; Jeliazkova, I; Nichols, CG | 1 |
| Altabef, AB; Hayes, SA; Navarro, A; Rankin, DW; Robertson, HE; Ruiz, TP; Tuttolomondo, ME; Varetti, EL; Wann, DA | 1 |
| Carvajal, K; De la Mora-De la Mora, I; Enriquez-Flores, S; Gutierrez-Castrellon, P; Hernandez-Alcantara, G; Lopez-Velazquez, G; Reyes-Vivas, H; Rodriguez-Romero, A | 1 |
| Gardonio, D; Siemann, S | 1 |
| Fukuta, M; Yamashita, I | 1 |
| Dasgupta, A; Jha, SK; Malhotra, P; Udgaonkar, JB | 1 |
| Harris, RA; Howard, RJ; Johnson, WD; Trudell, JR | 1 |
| Bhargava, P; Kumar, K; Roy, U | 1 |
| Ben Altabef, A; Defonsi Lestard, ME; Díaz, SB; Pierini, AB; Puiatti, M; Sánchez Cortez, S; Tuttolomondo, ME | 1 |
| Carroll, KS; Pan, J | 1 |
| Czajkowski, C; Ghosh, B; Satyshur, KA | 1 |
| Bechtold, E; Furdui, CM; King, SB; Poole, LB; Reisz, JA | 1 |
| Hoshina, MM; Marin-Morales, MA | 1 |
| Altabef, AB; Defonsi Lestard, ME; Díaz, SB; Miguel, V; Pierini, AB; Puiatti, M; Tuttolomondo, ME | 1 |
| Lefer, DJ; Li, Z; Organ, CL; Trivedi, RK; Wang, B; Wang, S; Yu, B; Yuan, Z; Zheng, Y | 1 |
| Alsford, S; Briggs, E; Fernandez-Cortes, F; Hamilton, G; Horn, D; Lemgruber, L; McCulloch, R; Mottram, JC; Serafim, TD; Stortz, JA; Wilkes, J | 1 |
| Akaike, T; Bianco, C; Bogdándi, V; Ditrói, T; Feelisch, M; Fukuto, JM; Henthorn, HA; Ida, T; Koster, G; Minnion, M; Nagy, P; Pluth, MD; Sutton, TR; Toscano, JP; van der Vliet, A | 1 |
| Barbosa da Silva, E; Brandstetter, H; Briza, P; Dall, E; Ferreira, RS | 1 |
| Baksheeva, VE; Gorokhovets, NV; Makarov, VA; Petushkova, AI; Savvateeva, LV; Serebryakova, MV; Tikhomirova, NK; Zamyatnin, AA; Zernii, EY | 1 |
| Choe, DH; Walton, WE; Why, AM | 1 |
123 other study(ies) available for methyl methanethiosulfonate and methyl methanesulfonate
| Article | Year |
|---|---|
Characterization of cysteine residues of glutathione S-transferase P: evidence for steric hindrance of substrate binding by a bulky adduct to cysteine 47.
Topics: Amino Acid Sequence; Base Sequence; Binding Sites; Carbon Isotopes; Cloning, Molecular; Cysteine; Escherichia coli; Glutathione Transferase; Isoenzymes; Kinetics; Magnetic Resonance Spectroscopy; Methyl Methanesulfonate; Molecular Sequence Data; Mutagenesis, Site-Directed; Oligodeoxyribonucleotides; Oxadiazoles; Peptide Fragments; Protein Binding; Protein Conformation; Recombinant Proteins | 1992 |
Role of cysteines 640, 656, and 661 in steroid binding to rat glucocorticoid receptors.
Topics: Affinity Labels; Animals; Arsenic; Arsenites; Base Sequence; Blotting, Western; Cysteine; Dexamethasone; Electrophoresis, Polyacrylamide Gel; Heat-Shock Proteins; Methyl Methanesulfonate; Molecular Sequence Data; Mutation; Peptide Fragments; Rats; Receptors, Glucocorticoid; Steroids; Substrate Specificity; Transfection | 1992 |
Glucocorticoid receptor binding to calf thymus DNA. 2. Role of a DNA-binding activity factor in receptor heterogeneity and a multistep mechanism of receptor activation.
Topics: Animals; Arsenic; Arsenites; Cattle; Chemical Phenomena; Chemistry; Chromatography, Gel; Cytosol; Dextrans; DNA; DNA-Binding Proteins; Methyl Methanesulfonate; Molybdenum; Receptors, Glucocorticoid; Sodium Compounds; Thymus Gland | 1990 |
Enhanced replication of herpes simplex virus type 1 in human cells.
Topics: Cell Line; DNA Damage; DNA Repair; DNA Replication; DNA, Viral; Fibroblasts; Gamma Rays; Humans; Lung; Methyl Methanesulfonate; Simplexvirus; Time Factors; Ultraviolet Rays; Viral Plaque Assay; Virus Activation | 1991 |
Peroxide modification of monoalkylated glutathione reductase. Stabilization of an active-site cysteine-sulfenic acid.
Topics: Alkylation; Binding Sites; Chromatography, Gel; Dithiothreitol; Electrophoresis, Polyacrylamide Gel; Glutathione Reductase; Hydrogen Peroxide; Iodoacetamide; Methyl Methanesulfonate; NADP; Oxidation-Reduction; Phenylmercuric Acetate; Saccharomyces cerevisiae | 1991 |
The identification of a structurally important cysteine residue in the glycerol dehydrogenase from Bacillus stearothermophilus.
Topics: Chemical Phenomena; Chemistry; Chromatography, High Pressure Liquid; Cobalt; Cysteine; Diethyl Pyrocarbonate; Dithionitrobenzoic Acid; Geobacillus stearothermophilus; Histidine; Iodoacetates; Iodoacetic Acid; Kinetics; Macromolecular Substances; Methyl Methanesulfonate; Molecular Weight; Peptide Fragments; Sugar Alcohol Dehydrogenases; Tritium; Trypsin; Zinc | 1991 |
6-Mercapto-FAD and 6-thiocyanato-FAD as active site probes of phenol hydroxylase.
Topics: Binding Sites; Chlorobenzoates; Dithiothreitol; Ethylmaleimide; Flavin-Adenine Dinucleotide; Hydrogen Peroxide; Hydrogen-Ion Concentration; Methyl Methanesulfonate; Mixed Function Oxygenases; Molecular Probes; Molecular Structure; Phenols; Spectrum Analysis | 1991 |
Localization of the vicinal dithiols involved in steroid binding to the rat glucocorticoid receptor.
Topics: Animals; Antibodies; Arsenic; Arsenites; Chemical Phenomena; Chemistry; Chymotrypsin; Disulfides; Methyl Methanesulfonate; Peptide Fragments; Rats; Receptors, Glucocorticoid; Sodium Compounds; Steroids; Sulfhydryl Compounds | 1990 |
Evidence for inhibitory SH groups in the thiol activated K:Cl cotransporter of low K sheep red blood cells.
Topics: Animals; Biological Transport; Carrier Proteins; Chlorides; Diamide; Dithiothreitol; Erythrocytes; Ethylmaleimide; Hydrogen-Ion Concentration; K Cl- Cotransporters; Kinetics; Methyl Methanesulfonate; Ouabain; Potassium; Sheep; Sulfhydryl Compounds; Symporters | 1990 |
Selective molybdate-directed covalent modification of sulfhydryl groups in the steroid-binding versus the DNA-binding domain of the glucocorticoid receptor.
Topics: Affinity Labels; Animals; Binding Sites; Cysteine; Cytosol; Dexamethasone; DNA-Binding Proteins; Ethylmaleimide; Hydrogen Peroxide; Kinetics; L Cells; Methyl Methanesulfonate; Mice; Molecular Weight; Molybdenum; Receptors, Glucocorticoid; Sulfhydryl Compounds; Sulfhydryl Reagents | 1990 |
Thionamides and arsenite inhibit specific T3 binding to the hepatic nuclear receptor.
Topics: Animals; Arsenic; Arsenites; Cell Nucleus; Chromatography, Liquid; Dithiothreitol; Liver; Methimazole; Methyl Methanesulfonate; Propylthiouracil; Rats; Receptors, Thyroid Hormone; Sodium Compounds; Sulfhydryl Reagents; Triiodothyronine | 1990 |
Cysteine 532 and cysteine 545 are the N-ethylmaleimide-reactive residues of the Neurospora plasma membrane H+-ATPase.
Topics: Amino Acid Sequence; Animals; Binding Sites; Cysteine; Cytoplasm; Ethylmaleimide; Fungal Proteins; Methyl Methanesulfonate; Molecular Sequence Data; Naphthalenesulfonates; Neurospora; Neurospora crassa; Peptide Fragments; Proton-Translocating ATPases; Rabbits; Rats; Sequence Homology, Nucleic Acid; Sheep; Swine | 1989 |
The active site sulfhydryl of aconitase is not required for catalytic activity.
Topics: Acetophenones; Aconitate Hydratase; Binding Sites; Dithionitrobenzoic Acid; Electron Spin Resonance Spectroscopy; Ethylmaleimide; Kinetics; Methyl Methanesulfonate; Sulfhydryl Reagents | 1988 |
3-Hydroxy-3-methylglutaryl-coenzyme A synthase from ox liver. Properties of its acetyl derivative.
Topics: Acetyl Coenzyme A; Animals; Binding Sites; Cattle; Coenzyme A; Hydroxymethylglutaryl-CoA Synthase; Macromolecular Substances; Methyl Methanesulfonate; Mitochondria, Liver; Oxo-Acid-Lyases; Pyruvates; Temperature | 1985 |
Sulfhydryl groups of rabbit liver arylsulfatase A.
Topics: Animals; Cerebroside-Sulfatase; Chromatography, Gel; Dithionitrobenzoic Acid; Fluorescent Dyes; Hydrogen-Ion Concentration; Hydroxymercuribenzoates; Liver; Methyl Methanesulfonate; Naphthalenesulfonates; Phenylmercury Compounds; Rabbits; Spectrometry, Fluorescence; Sulfatases; Sulfhydryl Compounds; Time Factors | 1985 |
Identification of subsidiary catalytic groups at the active site of beta-ketoacyl-CoA thiolase by covalent modification of the protein.
Topics: Acetyl Coenzyme A; Acetyl-CoA C-Acetyltransferase; Acetyltransferases; Acyl Coenzyme A; Amines; Anhydrides; Animals; Binding Sites; Catalysis; Cysteine; Cytosol; Hydrogen-Ion Concentration; Liver; Methyl Methanesulfonate; Rats; Sulfhydryl Compounds; Swine | 1986 |
Inactivation of chicken liver mevalonate 5-diphosphate decarboxylase by sulfhydryl-directed reagents: evidence of a functional dithiol.
Topics: Adenosine Triphosphate; Animals; Arsenicals; Carboxy-Lyases; Chickens; Dithionitrobenzoic Acid; Dithiothreitol; Enzyme Activation; Hydrogen-Ion Concentration; Kinetics; Liver; Methyl Methanesulfonate; Mevalonic Acid; Sulfhydryl Reagents; Toluene | 1989 |
A comparison of the kinetic properties of native bovine muscle carbonic anhydrase and an activated derivative with modified thiol groups.
Topics: Alkylation; Animals; Carbonic Anhydrases; Cattle; Enzyme Activation; Iodoacetamide; Kinetics; Magnetic Resonance Spectroscopy; Methyl Methanesulfonate; Muscles | 1988 |
Reversible dissociation of active octamer of cyanase to inactive dimer promoted by alteration of the sulfhydryl group.
Topics: Aminohydrolases; Azides; Bicarbonates; Carbon-Nitrogen Lyases; Chromatography, Gel; Cysteine; Enzyme Activation; Enzyme Reactivators; Escherichia coli; Ethylmaleimide; Macromolecular Substances; Mercuric Chloride; Methyl Methanesulfonate; Mutation; Oxalates; Oxalic Acid; Serine; Spectrometry, Fluorescence; Structure-Activity Relationship; Sulfhydryl Compounds; Tetranitromethane | 1988 |
Formation of mixed disulfide adducts at cysteine-281 of the lactose repressor protein affects operator and inducer binding parameters.
Topics: Cysteine; Cystine; Dansyl Compounds; Disulfides; Dithionitrobenzoic Acid; Escherichia coli; Isopropyl Thiogalactoside; Kinetics; Methyl Methanesulfonate; Nitrobenzoates; Operator Regions, Genetic; Protein Binding; Repressor Proteins; Transcription Factors | 1986 |
Characterization and modification of a monomeric mutant of the lactose repressor protein.
Topics: Antibodies, Monoclonal; Escherichia coli; Genes, Bacterial; Isopropyl Thiogalactoside; Kinetics; Methyl Methanesulfonate; Molecular Weight; Mutation; Repressor Proteins; Transcription Factors | 1986 |
Allosteric regulation of inducer and operator binding to the lactose repressor.
Topics: Allosteric Regulation; Escherichia coli; Genes, Bacterial; Genes, Regulator; Hydrogen-Ion Concentration; Kinetics; Ligands; Methyl Methanesulfonate; Operator Regions, Genetic; Protein Binding; Repressor Proteins; Transcription Factors | 1986 |
Irreversible inhibition of the human placental NADP-linked 15-hydroxyprostaglandin dehydrogenase/9-ketoprostaglandin reductase by glutathione thiosulfonate.
Topics: Binding Sites; Enzyme Inhibitors; Glutathione; Glutathione Disulfide; Humans; Hydroxyprostaglandin Dehydrogenases; Methyl Methanesulfonate; NADP; Oxidation-Reduction; Placenta; Prostaglandins A; Time Factors | 1987 |
The role of sulfhydryl groups in permitting transformation and DNA binding of the glucocorticoid receptor.
Topics: Animals; Cytosol; Dithiothreitol; DNA; Heat-Shock Proteins; Hot Temperature; Hydrogen Peroxide; Liver; Male; Methyl Methanesulfonate; Rats; Rats, Inbred Strains; Receptors, Glucocorticoid; Sulfhydryl Compounds | 1987 |
The heat-stable cytosolic factor that promotes glucocorticoid receptor binding to DNA is neither thioredoxin nor ribonuclease.
Topics: Animals; Bacterial Proteins; Cytosol; Dexamethasone; Dithiothreitol; DNA; Hot Temperature; Kinetics; Liver; Male; Methyl Methanesulfonate; Peptides; Protein Binding; Rats; Rats, Inbred Strains; Receptors, Glucocorticoid; Ribonucleases; Thioredoxins | 1987 |
Reactivity of small thiolate anions and cysteine-25 in papain toward methyl methanethiosulfonate.
Topics: Anions; Cysteine; Histidine; Hydrogen-Ion Concentration; Kinetics; Malates; Mathematics; Methyl Methanesulfonate; Papain; Protein Binding; Sulfhydryl Compounds | 1986 |
Inhibition of mammalian 5-lipoxygenase by aromatic disulfides.
Topics: Animals; Arachidonate Lipoxygenases; Arachidonic Acid; Arachidonic Acids; Basophils; Disulfides; Ethylmaleimide; Glutathione; Leukemia, Experimental; Lipoxygenase; Lipoxygenase Inhibitors; Methyl Methanesulfonate; Rats | 1985 |
Synthesis of methyl 2- and 4-pyridyl disulfide from 2- and 4-thiopyridone and methyl methanethiosulfonate.
Topics: Chemical Phenomena; Chemistry; Methyl Methanesulfonate; Pyridines; Sulfhydryl Compounds; Sulfhydryl Reagents | 1985 |
Inhibition of the functional interaction between fatty acid synthetase and thioesterase II by modification of a single cysteine thiol on the thioesterase.
Topics: Animals; Binding Sites; Chemical Phenomena; Chemistry; Cysteine; Dithionitrobenzoic Acid; Fatty Acid Synthases; Female; Hydrolysis; Kinetics; Methyl Methanesulfonate; Protein Binding; Rats; Sulfhydryl Compounds; Thiolester Hydrolases | 1985 |
Genetic toxicity of methyl methanethiosulfonate on Salmonella typhimurium, Saccharomyces cerevisiae and Nicotiana tabacum.
Topics: Cytoplasm; Methyl Methanesulfonate; Mutagenicity Tests; Nicotiana; Plants, Toxic; Saccharomyces cerevisiae; Salmonella typhimurium; Seeds | 1983 |
The pH dependence and group modification of beta-D-xylosidase from Bacillus pumilus: evidence for sulfhydryl and histidyl groups.
Topics: Allosteric Site; Bacillus; Catalysis; Chemical Phenomena; Chemistry; Diethyl Pyrocarbonate; Dithionitrobenzoic Acid; Glycoside Hydrolases; Histidine; Hydrogen-Ion Concentration; Kinetics; Methyl Methanesulfonate; Protein Binding; Sulfhydryl Compounds; Xylosidases | 1984 |
The mechanism of action of ethanolamine ammonia-lyase, an adenosylcobalamin-dependent enzyme. Evidence for a carboxyl group at the active site.
Topics: Ammonia-Lyases; Binding Sites; Cobamides; Ethanolamine Ammonia-Lyase; Ethyldimethylaminopropyl Carbodiimide; Glycine; Kinetics; Methyl Methanesulfonate | 1984 |
A functional role for cysteine disulfides in the transmembrane transport of diphtheria toxin.
Topics: Adenosine Diphosphate Ribose; Cell Survival; Diphtheria Toxin; HeLa Cells; Heparin-binding EGF-like Growth Factor; Humans; Intercellular Signaling Peptides and Proteins; Iodoacetamide; Iodoacetates; Kinetics; Mercury; Methyl Methanesulfonate; Receptors, Cell Surface; Receptors, Cholinergic | 1984 |
Blockade of acetylcholine synthesis in organophosphate poisoning.
Topics: Acetylcholine; Animals; Drug Interactions; Female; Lethal Dose 50; Male; Methyl Methanesulfonate; Mice; Organophosphorus Compounds; Rats; Sarin; Soman; Time Factors | 1984 |
Porphobilinogen synthase modification with methylmethanethiosulfonate. A protocol for the investigation of metalloproteins.
Topics: Animals; Apoproteins; Cattle; Kinetics; Ligands; Liver; Macromolecular Substances; Methyl Methanesulfonate; Porphobilinogen Synthase; Protein Binding; Zinc | 1984 |
Nonspecific inhibition of enzymes by p-bromophenacyl bromide. Inhibition of human platelet phospholipase C and modification of sulfhydryl groups.
Topics: Acetophenones; Blood Platelets; Cysteine; Cytosol; Dithionitrobenzoic Acid; Humans; Kinetics; Methyl Methanesulfonate; Phospholipases; Sulfhydryl Compounds; Type C Phospholipases | 1984 |
Studies with human erythrocyte pyruvate kinase (PK): effects of modification of sulfhydryl groups.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Alanine; Disulfides; Erythrocytes; Fructosediphosphates; Hot Temperature; Humans; Hydrogen-Ion Concentration; Kinetics; Methyl Methanesulfonate; Phosphoenolpyruvate; Pyruvate Kinase; Sulfhydryl Reagents; Tetrathionic Acid | 1983 |
Determination of interactive thiol ionizations in bovine serum albumin, glutathione, and other thiols by potentiometric difference titration.
Topics: Animals; Cattle; Chemical Phenomena; Chemistry; Glutathione; Hydrogen-Ion Concentration; Indicator Dilution Techniques; Methyl Methanesulfonate; Potentiometry; Serum Albumin, Bovine; Sulfhydryl Compounds | 1980 |
Methyl methanethiosulfonate as an active site probe of serine hydroxymethyltransferase.
Topics: Amino Acid Sequence; Animals; Binding Sites; Cytosol; Dithionitrobenzoic Acid; Glycine Hydroxymethyltransferase; Kinetics; Liver; Methyl Methanesulfonate; Peptide Fragments; Rabbits; Spectrophotometry; Transferases; Trypsin | 1982 |
Effect of chemical modification of sulfhydryl groups of human erythrocyte enzymes.
Topics: Catalysis; Erythrocytes; Glucosephosphate Dehydrogenase; Hot Temperature; Hydrogen-Ion Concentration; L-Lactate Dehydrogenase; Methyl Methanesulfonate; NADP; Phosphopyruvate Hydratase; Sulfhydryl Compounds | 1981 |
The chemical reactivity of the histidine-195 residue in lactate dehydrogenase thiomethylated at the cysteine-165 residue.
Topics: Binding Sites; Chemical Phenomena; Chemistry; Cysteine; Diethyl Pyrocarbonate; Formates; Histidine; Hydrogen-Ion Concentration; Kinetics; L-Lactate Dehydrogenase; Ligands; Methyl Methanesulfonate; Pyruvates; Sulfides | 1981 |
Amino group reactions of the sulfhydryl reagent methyl methanesulfonothioate. Inactivation of D-3-hydroxybutyrate dehydrogenase and reaction with amines in water.
Topics: Glycine; Glycylglycine; Hydroxybutyrate Dehydrogenase; Kinetics; Magnetic Resonance Spectroscopy; Methyl Methanesulfonate; Protein Binding; Sulfhydryl Reagents | 1980 |
Temperature-induced functional deocclusion of thiols inhibitory for sheep erythrocyte K-Cl cotransport.
Topics: Animals; Carrier Proteins; Erythrocytes; Ethylmaleimide; Glutathione; In Vitro Techniques; K Cl- Cotransporters; Methyl Methanesulfonate; Potassium; Sheep; Sulfhydryl Compounds; Symporters; Temperature | 1995 |
Use of hydrophobic affinity partitioning as a method for studying various conformational states of the human alpha-macroglobulins.
Topics: alpha-Macroglobulins; Centrifugation; Chemical Phenomena; Chemistry, Physical; Chymotrypsin; Humans; Macromolecular Substances; Methyl Methanesulfonate; Methylamines; Polyethylene Glycols; Protein Conformation | 1994 |
Disulfide bond formation by methanethiolation of the thiol ester sulfhydryl group of alpha 2M.
Topics: alpha-Macroglobulins; Chymotrypsin; Disulfides; Esters; Methyl Methanesulfonate; Sulfhydryl Compounds | 1994 |
Methanethiolation of the liberated cysteine residues of human alpha 2-macroglobulin treated with methylamine generates a derivative with similar functional characteristics as native alpha 2-macroglobulin.
Topics: alpha-Macroglobulins; Animals; Binding Sites; Cysteine; Drug Stability; Humans; In Vitro Techniques; Methyl Methanesulfonate; Methylamines; Mice; Molecular Structure; Sulfhydryl Reagents; Trypsin | 1995 |
Reactivity of the H(+)-ATPase from Kluyveromyces lactis to sulfhydryl reagents.
Topics: Adenosine Diphosphate; Binding Sites; Cell Membrane; Cysteine; Ethylmaleimide; Kinetics; Kluyveromyces; Magnesium Sulfate; Methyl Methanesulfonate; Proton-Translocating ATPases | 1995 |
Assay for thiols based on reactivation of papain.
Topics: Animals; Binding Sites; Cysteine; Disulfides; Dithionitrobenzoic Acid; Edetic Acid; Fabaceae; Fructose-Bisphosphate Aldolase; Indicators and Reagents; Kinetics; Methyl Methanesulfonate; Muscle, Skeletal; Oxidation-Reduction; Papain; Plants, Medicinal; Proteins; Rabbits; Sensitivity and Specificity; Serum Albumin, Bovine; Spectrophotometry; Sulfhydryl Compounds; Urease | 1995 |
Glucocorticoid receptor thiols and steroid-binding activity.
Topics: Affinity Labels; Amino Acid Sequence; Animals; Binding Sites; Chymotrypsin; Cysteine; DNA-Binding Proteins; HSP90 Heat-Shock Proteins; Kinetics; Liver; Methyl Methanesulfonate; Models, Structural; Mutagenesis, Site-Directed; Peptide Fragments; Protein Conformation; Rats; Receptors, Glucocorticoid; Recombinant Proteins; Steroids; Sulfhydryl Compounds; Sulfhydryl Reagents; Thioredoxins; Trypsin | 1995 |
Chemoprevention of azoxymethane-induced colon carcinogenesis by dietary feeding of S-methyl methane thiosulfonate in male F344 rats.
Topics: Animals; Anticarcinogenic Agents; Azoxymethane; Biogenic Polyamines; Bromodeoxyuridine; Colon; Colonic Neoplasms; Diet; Male; Methyl Methanesulfonate; Nucleolus Organizer Region; Ornithine Decarboxylase; Rats; Rats, Inbred F344 | 1995 |
Preparation and properties of recombinant corynebacterial sarcosine oxidase: evidence for posttranslational modification during turnover with sarcosine.
Topics: Chromatography, Gel; Cloning, Molecular; Corynebacterium; DNA, Bacterial; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Flavin-Adenine Dinucleotide; Methyl Methanesulfonate; Molecular Weight; Oxidoreductases, N-Demethylating; Plasmids; Protein Processing, Post-Translational; Recombinant Proteins; Sarcosine; Sarcosine Oxidase; Spectrophotometry; Sulfhydryl Compounds; Transformation, Bacterial | 1993 |
Sulfhydryl modification of the yeast Wbp1p inhibits oligosaccharyl transferase activity.
Topics: Amino Acid Sequence; Biotin; Carbohydrate Sequence; Catalysis; Cysteine; Dithiothreitol; Enzyme Stability; Hexosyltransferases; Kinetics; Macromolecular Substances; Membrane Proteins; Mesylates; Methyl Methanesulfonate; Microsomes; Molecular Sequence Data; Polyisoprenyl Phosphate Oligosaccharides; Saccharomyces cerevisiae; Structure-Activity Relationship; Sulfhydryl Compounds; Transferases | 1995 |
Trichodiene synthase. Identification of active site residues by site-directed mutagenesis.
Topics: Amino Acid Sequence; Base Sequence; Binding Sites; Carbon-Carbon Lyases; Catalysis; Cloning, Molecular; Cysteine; DNA Primers; DNA, Fungal; Escherichia coli; Fusarium; Kinetics; Lyases; Methyl Methanesulfonate; Molecular Sequence Data; Molecular Structure; Mutagenesis, Site-Directed; Polyisoprenyl Phosphates; Sesquiterpenes; Substrate Specificity | 1995 |
Metal oxyanion stabilization of the rat glucocorticoid receptor is independent of thiols.
Topics: Affinity Labels; Animals; Anions; Base Sequence; Cyclic GMP; Cysteine; Dexamethasone; Methyl Methanesulfonate; Molecular Sequence Data; Molybdenum; Mutation; Peptide Fragments; Rats; Receptors, Glucocorticoid; Structure-Activity Relationship; Sulfhydryl Compounds; Trypsin; Tungsten Compounds; Vanadates | 1994 |
The activity of S-thiomethyl modified creatine kinase is due to the regeneration of free thiol at the active site.
Topics: Animals; Binding Sites; Creatine Kinase; Dithionitrobenzoic Acid; Enzyme Activation; Methyl Methanesulfonate; Muscles; Rabbits; Sulfhydryl Compounds | 1994 |
Factor-assisted DNA binding as a possible general mechanism for steroid receptors. Functional heterogeneity among activated receptor-steroid complexes.
Topics: Animals; Arsenites; Biological Factors; Cell Line; Cell Nucleus; DNA; DNA-Binding Proteins; Electrophoresis, Gel, Two-Dimensional; HeLa Cells; Humans; Male; Methyl Methanesulfonate; Protein Binding; Rats; Rats, Sprague-Dawley; Receptors, Estrogen; Receptors, Glucocorticoid; Receptors, Progesterone; Sodium Compounds; Tumor Cells, Cultured | 1994 |
S-methyl methane thiosulfonate, a new antimutagenic compound isolated from Brassica oleracea L. var. botrytis.
Topics: Antimutagenic Agents; Brassica; Escherichia coli; Magnetic Resonance Spectroscopy; Mass Spectrometry; Methyl Methanesulfonate; Ultraviolet Rays | 1993 |
Spatial proximity and sequence localization of the reactive sulfhydryls of porphobilinogen synthase.
Topics: Amino Acid Sequence; Animals; Cattle; Cysteine; Electron Spin Resonance Spectroscopy; Methyl Methanesulfonate; Molecular Sequence Data; Molecular Structure; Peptide Mapping; Porphobilinogen Synthase; Spin Labels; Sulfhydryl Compounds | 1993 |
Effects of sulfhydryl reagents on the Cys65 mutant of the transposon Tn10-encoded metal-tetracycline/H+ antiporter of Escherichia coli.
Topics: Amino Acid Sequence; Antiporters; Aspartic Acid; Bacterial Proteins; Carrier Proteins; Cysteine; DNA Transposable Elements; Escherichia coli; Ethylmaleimide; Methyl Methanesulfonate; Models, Molecular; Molecular Sequence Data; Mutation; Protein Conformation; Repressor Proteins; Structure-Activity Relationship; Sulfhydryl Reagents; Tetracycline; Tetracycline Resistance | 1993 |
Steroidal affinity labels of the estrogen receptor. 1. 17 alpha-(Bromoacetoxy)alkyl/alkynylestradiols.
Topics: Acetates; Affinity Labels; Animals; Binding Sites; Binding, Competitive; Cytosol; Dose-Response Relationship, Drug; Epoxy Compounds; Estradiol; Female; Hydrogen-Ion Concentration; Ligands; Methyl Methanesulfonate; Receptors, Estrogen; Sheep | 1993 |
Differential effects of the reversible thiol-reactive agents arsenite and methyl methanethiosulfonate on steroid binding by the glucocorticoid receptor.
Topics: Animals; Arsenic; Arsenites; Binding Sites; Cell Line; Cytosol; Dexamethasone; DNA; Ethylmaleimide; Heat-Shock Proteins; Hydrogen-Ion Concentration; Iodoacetamide; L Cells; Methyl Methanesulfonate; Mice; Receptors, Glucocorticoid; Triamcinolone Acetonide | 1993 |
Sulfhydryl groups are involved in the binding of agonists and antagonists to the human mineralocorticoid receptor.
Topics: Aldosterone; Cell-Free System; Cysteine; Humans; Kinetics; Methyl Methanesulfonate; Mineralocorticoid Receptor Antagonists; Mineralocorticoids; Protein Binding; Receptors, Mineralocorticoid; Recombinant Proteins; Spironolactone; Sulfhydryl Reagents | 1996 |
Two conformationally vicinal thiols at the active site of Leishmania donovani adenosine kinase.
Topics: Adenosine; Adenosine Kinase; Animals; Arsenites; Binding Sites; Chromatography, Agarose; Diamide; Dimercaprol; Disulfides; Enzyme Inhibitors; Ethylmaleimide; Kinetics; Leishmania donovani; Methyl Methanesulfonate; Spectrometry, Fluorescence; Sulfhydryl Compounds | 1996 |
Essential cysteines in 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase from Escherichia coli: analysis by chemical modification and site-directed mutagenesis.
Topics: Aldehyde-Lyases; Base Sequence; Binding Sites; Cysteine; Dithionitrobenzoic Acid; Enzyme Inhibitors; Escherichia coli; Methyl Methanesulfonate; Molecular Sequence Data; Pentosephosphates; Phosphoenolpyruvate; Recombinant Proteins; Structure-Activity Relationship; Sulfhydryl Reagents | 1996 |
The conformational state of human alpha 2-macroglobulin influences its dissociation into half-molecules by sodium thiocyanate.
Topics: alpha-Macroglobulins; Humans; In Vitro Techniques; Methyl Methanesulfonate; Methylamines; Protein Conformation; Spectrometry, Fluorescence; Thiocyanates; Trypsin | 1996 |
Recombinant human phenylethanolamine N-methyltransferase: overproduction in Escherichia coli, purification, and characterization.
Topics: Amino Acid Sequence; Chromatography, Ion Exchange; Cloning, Molecular; Diethyl Pyrocarbonate; DNA Primers; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Gene Expression; Humans; Imidoesters; Iodoacetamide; Kinetics; Methyl Methanesulfonate; Molecular Sequence Data; Phenylethanolamine N-Methyltransferase; Phenylglyoxal; Plasmids; Recombinant Proteins; S-Adenosylmethionine; Tetranitromethane | 1996 |
S-methyl methanethiosulfonate, bio-antimutagen in homogenates of Cruciferae and Liliaceae vegetables.
Topics: Antimutagenic Agents; Brassica; Cysteine; Hydrogen-Ion Concentration; Methyl Methanesulfonate; Mutagenicity Tests; Vegetables | 1996 |
Methanethiosulfonate derivatives inhibit current through the ryanodine receptor/channel.
Topics: Animals; Calcium Channels; Cytoplasm; Ethyl Methanesulfonate; In Vitro Techniques; Ion Channels; Lipid Bilayers; Methyl Methanesulfonate; Microsomes; Muscle Proteins; Muscles; Rabbits; Ryanodine; Ryanodine Receptor Calcium Release Channel; Sulfhydryl Compounds; Thiosulfates | 1997 |
Suppressive effects of S-methyl methanethiosulfonate on promotion stage of diethylnitrosamine-initiated and phenobarbital-promoted hepatocarcinogenesis model.
Topics: Animals; Anticarcinogenic Agents; Diethylnitrosamine; Lipid Peroxidation; Liver Neoplasms, Experimental; Male; Methyl Methanesulfonate; Ornithine Decarboxylase; Phenobarbital; Rabbits; Rats; Rats, Inbred F344 | 1997 |
Cloning, expression, purification and characterization of triosephosphate isomerase from Trypanosoma cruzi.
Topics: Amino Acid Sequence; Animals; Base Sequence; Cloning, Molecular; DNA, Complementary; DNA, Protozoan; Enzyme Inhibitors; Gene Expression; Genes, Protozoan; Kinetics; Leishmania mexicana; Methyl Methanesulfonate; Molecular Sequence Data; Polymerase Chain Reaction; Recombinant Proteins; Sequence Homology, Amino Acid; Species Specificity; Triose-Phosphate Isomerase; Trypanosoma brucei brucei; Trypanosoma cruzi | 1997 |
Mercurochrom can be used for the histochemical demonstration and microphotometric quantitation of both protein thiols and protein (mixed) disulfides.
Topics: Animals; Carcinoma, Ehrlich Tumor; Chickens; Disulfides; Histocytochemistry; Liver; Merbromin; Methyl Methanesulfonate; Mice; Photometry; Proteins; Rats; Staining and Labeling; Sulfhydryl Compounds; Sulfhydryl Reagents; T-Lymphocytes | 1997 |
Regressive effects of various chemopreventive agents on azoxymethane-induced aberrant crypt foci in the rat colon.
Topics: 4-Butyrolactone; Animals; Anticarcinogenic Agents; Azoxymethane; Body Weight; Carcinogens; Chemoprevention; Chlorogenic Acid; Colonic Neoplasms; Drug Administration Schedule; Male; Methyl Methanesulfonate; Piroxicam; Rats; Rats, Inbred F344; Retinoids | 1997 |
Suppressing effects of S-methyl methanethiosulfonate and diphenyl disulfide on mitomycin C-induced somatic mutation and recombination in Drosophila melanogaster and micronuclei in mice.
Topics: Animals; Antimutagenic Agents; Disulfides; Drosophila melanogaster; Male; Methyl Methanesulfonate; Mice; Mice, Inbred ICR; Micronucleus Tests; Mitomycin; Mutagens; Mutation; Recombination, Genetic; Reticulocytes; Wings, Animal | 1997 |
Suppression of aflatoxin B1- or methyl methanesulfonate-induced chromosome aberrations in rat bone marrow cells after treatment with S-methyl methanethiosulfonate.
Topics: Aflatoxin B1; Animals; Antimutagenic Agents; Bone Marrow Cells; Brassica; Chromosome Aberrations; Disulfides; Male; Methyl Methanesulfonate; Mutagens; Onions; Plant Extracts; Rats; Rats, Wistar | 1997 |
Cobalamin-dependent methionine synthase from Escherichia coli: involvement of zinc in homocysteine activation.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Catalysis; Edetic Acid; Escherichia coli; Homocysteine; Methyl Methanesulfonate; Methylation; Mutagenesis; Protein Binding; Protons; Recombinant Proteins; Spectrophotometry; Spectrum Analysis; Tetrahydrofolates; Vitamin B 12; Zinc | 1997 |
Contribution of the NH2 terminus of Kv2.1 to channel activation.
Topics: Amino Acid Sequence; Amino Acid Substitution; Animals; Delayed Rectifier Potassium Channels; Dithiothreitol; Ion Channel Gating; Kinetics; Membrane Potentials; Methyl Methanesulfonate; Mutagenesis, Insertional; Mutagenesis, Site-Directed; Oocytes; Potassium Channels; Potassium Channels, Voltage-Gated; Recombinant Proteins; Sequence Deletion; Shab Potassium Channels | 1997 |
Cysteine-scanning mutagenesis around transmembrane segment III of Tn10-encoded metal-tetracycline/H+ antiporter.
Topics: Amino Acid Sequence; Antiporters; Bacterial Proteins; Biological Transport; Cysteine; DNA Transposable Elements; Ethylmaleimide; Metals; Methyl Methanesulfonate; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Structure, Secondary; Protons; Sulfhydryl Reagents; Tetracyclines | 1998 |
Allosteric regulation of pyruvate kinase M2 isozyme involves a cysteine residue in the intersubunit contact.
Topics: Allosteric Regulation; Amino Acid Sequence; Animals; Cell Line; Cysteine; Enzyme Activation; Isoenzymes; Kinetics; Methyl Methanesulfonate; Molecular Sequence Data; Mutagenesis, Site-Directed; Pyruvate Kinase; Rats; Sequence Homology, Amino Acid; Spodoptera | 1998 |
Changes in side chain packing during apomyoglobin folding characterized by pulsed thiol-disulfide exchange.
Topics: Amino Acids, Sulfur; Apoproteins; Cysteine; Cystine; Disulfides; Dithionitrobenzoic Acid; Flow Injection Analysis; Kinetics; Methyl Methanesulfonate; Models, Chemical; Models, Molecular; Mutagenesis, Site-Directed; Myoglobin; Protein Denaturation; Protein Engineering; Protein Folding; Spectrometry, Fluorescence; Sulfhydryl Compounds; Sulfhydryl Reagents | 1998 |
Differences in the intersubunit contacts in triosephosphate isomerase from two closely related pathogenic trypanosomes.
Topics: Amino Acid Sequence; Animals; Binding Sites; Crystallography, X-Ray; Dimerization; Dithionitrobenzoic Acid; Humans; Methyl Methanesulfonate; Models, Molecular; Molecular Sequence Data; Protein Conformation; Protein Structure, Secondary; Recombinant Proteins; Sequence Alignment; Sulfhydryl Reagents; Triose-Phosphate Isomerase; Trypanosoma brucei brucei; Trypanosoma cruzi | 1998 |
DNA polymerase III of Gram-positive eubacteria is a zinc metalloprotein conserving an essential finger-like domain.
Topics: Amino Acid Sequence; Bacillus subtilis; Binding Sites; Catalysis; Conserved Sequence; Cysteine; DNA Polymerase III; Electrons; Gram-Positive Bacteria; Histidine; Iron; Metalloendopeptidases; Methyl Methanesulfonate; Molecular Sequence Data; Point Mutation; Protein Structure, Tertiary; Recombinant Proteins; Zinc Fingers; Zinc Radioisotopes | 1998 |
Different populations of progesterone receptor-steroid complexes in binding to specific DNA sequences: effects of salts on kinetics and specificity.
Topics: Ammonium Sulfate; Animals; Arsenites; Base Sequence; Binding Sites; Cattle; Cell Line; DNA; Drug Stability; Humans; In Vitro Techniques; Kinetics; Methyl Methanesulfonate; Oligodeoxyribonucleotides; Rats; Receptors, Progesterone; Salts; Steroids | 1998 |
Derivatization of the interface cysteine of triosephosphate isomerase from Trypanosoma brucei and Trypanosoma cruzi as probe of the interrelationship between the catalytic sites and the dimer interface.
Topics: Animals; Catalysis; Cysteine; Dimerization; Dithionitrobenzoic Acid; Enzyme Activation; Enzyme Inhibitors; Glyceraldehyde 3-Phosphate; Glycolates; Methyl Methanesulfonate; Mutagenesis, Site-Directed; Serine; Substrate Specificity; Sulfhydryl Reagents; Triose-Phosphate Isomerase; Trypanosoma brucei brucei; Trypanosoma cruzi | 1999 |
Modification of leukotriene A(4) hydrolase/aminopeptidase by sulfhydryl-blocking reagents: differential effects on dual enzyme activities by methyl-methane thiosulfonate.
Topics: Binding, Competitive; Catalytic Domain; Enzyme Reactivators; Epoxide Hydrolases; Humans; Hydrogen-Ion Concentration; In Vitro Techniques; Kinetics; Mercaptoethanol; Methyl Methanesulfonate; Recombinant Proteins; Substrate Specificity; Sulfhydryl Reagents | 1999 |
The roles of two amino acid residues in the active site of L-lactate monooxygenase. Mutation of arginine 187 to methionine and histidine 240 to glutamine.
Topics: Arginine; Catalytic Domain; Histidine; Hydrogen Peroxide; Lactic Acid; Methyl Methanesulfonate; Mixed Function Oxygenases; Models, Chemical; Models, Molecular; Mutagenesis, Site-Directed; Mutation; Oxalates; Oxidation-Reduction; Stereoisomerism; Substrate Specificity | 1999 |
Steroidal affinity labels of the estrogen receptor alpha. 4. Electrophilic 11beta-aryl derivatives of estradiol.
Topics: Affinity Labels; Animals; Cytosol; Estradiol; Female; Humans; In Vitro Techniques; Indicators and Reagents; Methyl Methanesulfonate; Radioligand Assay; Receptors, Estrogen; Sheep; Structure-Activity Relationship; Uterus | 2000 |
Irreversible extrusion of the first loop facing the matrix of the bovine heart mitochondrial ADP/ATP carrier by labeling the Cys(56) residue with the SH-reagent methyl methanethiosulfonate.
Topics: Adenosine Diphosphate; Animals; Cattle; Cross-Linking Reagents; Cysteine; Dose-Response Relationship, Drug; Methyl Methanesulfonate; Mitochondria, Heart; Mitochondrial ADP, ATP Translocases; Models, Chemical; Phenanthrolines; Protein Conformation; Protein Structure, Tertiary; Sulfhydryl Reagents; Time Factors | 2000 |
Modification of cysteines reveals linkage to acetylcholine and vesamicol binding sites in the vesicular acetylcholine transporter of Torpedo californica.
Topics: 4-Chloromercuribenzenesulfonate; Acetylcholine; Amino Acid Sequence; Animals; Base Sequence; Binding Sites; Binding, Competitive; Carrier Proteins; Cysteine; Cytoplasm; Dose-Response Relationship, Drug; Glutathione; Membrane Transport Proteins; Methyl Methanesulfonate; Methylmercury Compounds; Molecular Sequence Data; Neuromuscular Depolarizing Agents; Organomercury Compounds; Phenylmercury Compounds; Piperidines; Protein Structure, Tertiary; Torpedo; Vesicular Acetylcholine Transport Proteins; Vesicular Transport Proteins | 2000 |
Cysteine residues and the structure of the rat renal proximal tubular type II sodium phosphate cotransporter (rat NaPi IIa).
Topics: Amino Acid Sequence; Amino Acid Substitution; Animals; Carrier Proteins; Cysteine; Disulfides; Ethyl Methanesulfonate; Kidney Tubules, Proximal; Mesylates; Methyl Methanesulfonate; Molecular Sequence Data; Mutagenesis, Site-Directed; Oocytes; Protein Structure, Tertiary; Rats; Reducing Agents; Serine; Sodium-Phosphate Cotransporter Proteins; Sodium-Phosphate Cotransporter Proteins, Type II; Sodium-Phosphate Cotransporter Proteins, Type IIa; Symporters; Xenopus laevis | 2000 |
Differential inhibition of human platelet aggregation by selected Allium thiosulfinates.
Topics: Allium; Disulfides; Humans; Methyl Methanesulfonate; Platelet Aggregation; Platelet Aggregation Inhibitors; Regression Analysis; Structure-Activity Relationship; Sulfinic Acids; Sulfonic Acids | 2000 |
Flexibility of the Kir6.2 inward rectifier K(+) channel pore.
Topics: Amino Acid Sequence; Animals; Cadmium; COS Cells; Cysteine; Dimerization; Ethyl Methanesulfonate; Indicators and Reagents; Mesylates; Methyl Methanesulfonate; Models, Biological; Models, Molecular; Molecular Sequence Data; Pliability; Point Mutation; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Inwardly Rectifying; Protein Conformation; Quaternary Ammonium Compounds; Sequence Homology, Amino Acid | 2001 |
Feeding thiol-containing compounds, derived from vegetables, fails to inhibit N-methylnitrosourea-induced mammary tumorigenesis.
Topics: Administration, Oral; Animal Feed; Animals; Chemoprevention; Female; Incidence; Mammary Neoplasms, Experimental; Methyl Methanesulfonate; Plant Extracts; Rats; Rats, Sprague-Dawley; Thiones; Thiophenes; Vegetables | 2001 |
On the nature of conformational openings: native and unfolded-state hydrogen and thiol-disulfide exchange studies of ferric aquomyoglobin.
Topics: Amides; Animals; Circular Dichroism; Cysteine; Disulfides; Dithionitrobenzoic Acid; Guanidine; Hydrogen; Kinetics; Methyl Methanesulfonate; Models, Molecular; Mutation; Myoglobin; Protein Conformation; Protein Folding; Sulfhydryl Compounds; Thermodynamics; Whales | 2001 |
Mechanism-based inactivation of thioredoxin reductase from Plasmodium falciparum by Mannich bases. Implication for cytotoxicity.
Topics: Alkylating Agents; Animals; Dithionitrobenzoic Acid; Dose-Response Relationship, Drug; Enzyme Inhibitors; Glutathione; Glutathione Reductase; Humans; Hydrogen-Ion Concentration; Kinetics; Mannich Bases; Methyl Methanesulfonate; Models, Chemical; NADP; Oxidation-Reduction; Plasmodium falciparum; Propiophenones; Thioredoxin-Disulfide Reductase | 2003 |
Osmotic water permeability and regulatory volume decrease of rat thymocytes.
Topics: Animals; Cell Membrane Permeability; Cell Size; Cells, Cultured; Dose-Response Relationship, Drug; Homeostasis; Mercuric Chloride; Methyl Methanesulfonate; Osmotic Pressure; Rats; Rats, Wistar; Sodium Chloride; T-Lymphocytes; Temperature; Thymus Gland; Water; Water-Electrolyte Balance | 2003 |
Thiol-disulphide interchange in tubulin: kinetics and the effect on polymerization.
Topics: 2,2'-Dipyridyl; Adenosine Triphosphate; Amino Acid Sequence; Biopolymers; Cysteine; Disulfides; Dithionitrobenzoic Acid; Guanosine Diphosphate; Guanosine Triphosphate; Kinetics; Methyl Methanesulfonate; Molecular Structure; Nitrobenzoates; Protein Denaturation; Sulfhydryl Compounds; Tubulin | 2005 |
Conformation-dependent inactivation of human betaine-homocysteine S-methyltransferase by hydrogen peroxide in vitro.
Topics: Betaine-Homocysteine S-Methyltransferase; Binding Sites; Circular Dichroism; Enzyme Activation; Glutaral; Homocysteine; Humans; Hydrogen Peroxide; Mercaptoethanol; Methyl Methanesulfonate; Models, Molecular; Oxidation-Reduction; Protein Binding; Protein Conformation; Zinc | 2005 |
Antigenotoxic effect of allicin against methyl methanesulphonate induced genotoxic damage.
Topics: Animals; Chromosome Aberrations; Disulfides; Dose-Response Relationship, Drug; Humans; Lymphocytes; Methyl Methanesulfonate; Microsomes, Liver; Mutagenicity Tests; Rats; Recombination, Genetic; Sulfinic Acids | 2005 |
Disulfiram irreversibly aggregates betaine aldehyde dehydrogenase--a potential target for antimicrobial agents against Pseudomonas aeruginosa.
Topics: Alanine; Anti-Infective Agents; Betaine-Aldehyde Dehydrogenase; Binding Sites; Catalysis; Chromatography; Cysteine; Disulfiram; Dithionitrobenzoic Acid; Enzyme Inhibitors; Glutathione; Kinetics; Methyl Methanesulfonate; Models, Chemical; Mutagenesis, Site-Directed; Mutation; NADP; Protein Conformation; Protein Structure, Quaternary; Proteins; Pseudomonas aeruginosa; Sulfhydryl Compounds; Temperature; Time Factors | 2006 |
Identification of a stable flavin-thiolate adduct in heterotetrameric sarcosine oxidase.
Topics: Dithionitrobenzoic Acid; Flavin Mononucleotide; Methyl Methanesulfonate; Models, Molecular; Protein Structure, Quaternary; Pseudomonas; Sarcosine Oxidase; Sulfhydryl Compounds; Sulfides; Sulfites | 2006 |
Crosstalk between the subunits of the homodimeric enzyme triosephosphate isomerase.
Topics: Amino Acid Sequence; Animals; Cysteine; Dimerization; Kinetics; Methyl Methanesulfonate; Mutagenesis, Site-Directed; Protein Interaction Mapping; Protein Structure, Quaternary; Triose-Phosphate Isomerase; Trypanosoma brucei brucei; Trypanosoma cruzi | 2007 |
Does s-methyl methanethiosulfonate trap the thiol-disulfide state of proteins?
Topics: Disulfides; Electrophoresis, Polyacrylamide Gel; Methyl Methanesulfonate; Models, Chemical; Proteins | 2007 |
Identification of sequences that target BRCA1 to nuclear foci following alkylative DNA damage.
Topics: Alkylating Agents; Amino Acid Sequence; Ataxia Telangiectasia Mutated Proteins; BRCA1 Protein; Breast Neoplasms; Cell Cycle Proteins; Cell Line, Tumor; Cell Nucleus; DNA Breaks, Single-Stranded; DNA Damage; DNA Repair; DNA-Binding Proteins; Female; Humans; Methyl Methanesulfonate; Molecular Sequence Data; Mutation; Peptides; Phosphorylation; Protein Serine-Threonine Kinases; Protein Structure, Tertiary; Protein Transport; Radiation, Ionizing; Recombinant Fusion Proteins; Structure-Activity Relationship; X-ray Repair Cross Complementing Protein 1 | 2007 |
Control of inward rectifier K channel activity by lipid tethering of cytoplasmic domains.
Topics: Bacterial Proteins; Burkholderia pseudomallei; Cell-Free System; Cloning, Molecular; Cysteine; Ethyl Methanesulfonate; Ion Channel Gating; Membrane Lipids; Mesylates; Methyl Methanesulfonate; Models, Molecular; Mutation; Potassium Channels, Inwardly Rectifying; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Rubidium Radioisotopes; Sulfhydryl Reagents | 2007 |
Gas-phase structure, rotational barrier, and vibrational properties of methyl methanethiosulfonate, CH3SO2SCH3: an experimental and computational study.
Topics: Chemistry, Physical; Computer Simulation; Electrons; Fourier Analysis; Gases; Methyl Methanesulfonate; Models, Statistical; Models, Theoretical; Molecular Conformation; Software; Spectrophotometry, Infrared; Spectrum Analysis, Raman; Temperature; Thermodynamics | 2007 |
Species-specific inhibition of Giardia lamblia triosephosphate isomerase by localized perturbation of the homodimer.
Topics: Animals; Cysteine; Dimerization; Dithionitrobenzoic Acid; Enzyme Stability; Giardia lamblia; Hot Temperature; Methyl Methanesulfonate; Models, Molecular; Protein Structure, Secondary; Protozoan Proteins; Triose-Phosphate Isomerase | 2008 |
Chelator-facilitated chemical modification of IMP-1 metallo-beta-lactamase and its consequences on metal binding.
Topics: beta-Lactamases; Chelating Agents; Cysteine; Dinitrobenzenes; Methods; Methyl Methanesulfonate; Phosphines; Protein Binding; Thiocyanates; Zinc | 2009 |
Adsorption behavior of ferritin and buffer components, buffer agents and salts, onto silane-coupled silicon substrate.
Topics: Adsorption; Animals; Buffers; Carbon; Ferritins; HEPES; Horses; Hydrophobic and Hydrophilic Interactions; Isocyanates; Methyl Methanesulfonate; Microscopy, Atomic Force; Photoelectron Spectroscopy; Salts; Silanes; Silicon; Sodium; Solutions; Sulfur; Surface Properties; Water | 2010 |
Identification of multiple folding pathways of monellin using pulsed thiol labeling and mass spectrometry.
Topics: Cysteine; Kinetics; Methyl Methanesulfonate; Models, Molecular; Plant Proteins; Protein Folding; Protein Refolding; Protein Structure, Secondary; Solvents; Spectrometry, Fluorescence; Spectrometry, Mass, Electrospray Ionization; Staining and Labeling; Sulfhydryl Compounds; Tryptophan | 2011 |
The TM2 6' position of GABA(A) receptors mediates alcohol inhibition.
Topics: Alcohols; Amino Acid Substitution; Animals; Binding Sites; Binding, Competitive; Cysteine; Cystine; DNA, Complementary; Drug Synergism; Electrophysiological Phenomena; Ethanol; Etomidate; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Humans; Methionine; Methyl Methanesulfonate; Molecular Dynamics Simulation; Oocytes; Patch-Clamp Techniques; Receptors, GABA-A; Tryptophan; Xenopus laevis | 2012 |
Cloning, overexpression and characterization of Leishmania donovani triosephosphate isomerase.
Topics: Amino Acid Sequence; Blotting, Western; Chromatography, Gel; Cloning, Molecular; Electrophoresis, Polyacrylamide Gel; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Hydrogen-Ion Concentration; Leishmania donovani; Methyl Methanesulfonate; Molecular Sequence Data; Protein Conformation; Sequence Alignment; Triose-Phosphate Isomerase | 2012 |
Interaction of S-methyl methanethiosulfonate with DPPC bilayer.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Hydrophobic and Hydrophilic Interactions; Lipid Bilayers; Methyl Methanesulfonate; Models, Molecular; Nephelometry and Turbidimetry; Spectroscopy, Fourier Transform Infrared; Spectrum Analysis, Raman; Static Electricity; Vibration | 2012 |
Persulfide reactivity in the detection of protein s-sulfhydration.
Topics: Alkylating Agents; Biochemistry; Biotin; Hydrogen Sulfide; Mesylates; Methyl Methanesulfonate; Protein S; Sulfhydryl Compounds; Sulfides | 2013 |
Propofol binding to the resting state of the gloeobacter violaceus ligand-gated ion channel (GLIC) induces structural changes in the inter- and intrasubunit transmembrane domain (TMD) cavities.
Topics: Allosteric Regulation; Amino Acid Substitution; Anesthetics, Intravenous; Animals; Bacterial Proteins; Cyanobacteria; Cysteine; Hydrogen-Ion Concentration; Ion Channel Gating; Kinetics; Ligand-Gated Ion Channels; Membrane Potentials; Methyl Methanesulfonate; Molecular Docking Simulation; Mutagenesis, Site-Directed; Propofol; Protein Binding; Protein Interaction Domains and Motifs; Protein Stability; Protein Structure, Secondary; Protein Subunits; Structural Homology, Protein; Xenopus laevis | 2013 |
Thiol-blocking electrophiles interfere with labeling and detection of protein sulfenic acids.
Topics: Ascorbic Acid; Cyclohexanones; Cysteine; Dithiothreitol; Ethylmaleimide; Iodoacetamide; Methyl Methanesulfonate; Oxidation-Reduction; Proteins; Reactive Oxygen Species; Spectrometry, Mass, Electrospray Ionization; Sulfenic Acids; Sulfhydryl Compounds | 2013 |
Anti-genotoxicity and anti-mutagenicity of Apis mellifera venom.
Topics: Animals; Antimutagenic Agents; Bee Venoms; Bees; Cell Survival; DNA Damage; Dose-Response Relationship, Drug; Hep G2 Cells; Humans; Methyl Methanesulfonate; Micronuclei, Chromosome-Defective; Mutagenicity Tests; Mutagens | 2014 |
Molecular view of the interaction of S-methyl methanethiosulfonate with DPPC bilayer.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Diffusion; Dimethyl Sulfoxide; Lipid Bilayers; Methyl Methanesulfonate; Molecular Dynamics Simulation; Thermodynamics | 2016 |
An Esterase-Sensitive Prodrug Approach for Controllable Delivery of Persulfide Species.
Topics: Activation, Metabolic; Animals; Cardiotonic Agents; Cell Line; Dose-Response Relationship, Drug; Drug Development; Esterases; Methyl Methanesulfonate; Mice; Myocardial Reperfusion Injury; Prodrugs; Sulfides | 2017 |
Genome-wide and protein kinase-focused RNAi screens reveal conserved and novel damage response pathways in Trypanosoma brucei.
Topics: DNA Damage; DNA Repair; Evolution, Molecular; Genome, Protozoan; Methyl Methanesulfonate; Mutagens; Protein Kinases; Protozoan Proteins; RNA Interference; Trypanosoma brucei brucei | 2017 |
Speciation of reactive sulfur species and their reactions with alkylating agents: do we have any clue about what is present inside the cell?
Topics: Adult; Alkylating Agents; Humans; Iodoacetamide; Maleimides; Methyl Methanesulfonate; Sulfur Compounds | 2019 |
Cruzain structures: apocruzain and cruzain bound to S-methyl thiomethanesulfonate and implications for drug design.
Topics: Apoproteins; Crystallography, X-Ray; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Drug Design; Methyl Methanesulfonate; Models, Molecular; Protein Conformation; Protozoan Proteins | 2019 |
Novel applications of modification of thiol enzymes and redox-regulated proteins using S-methyl methanethiosulfonate (MMTS).
Topics: Animals; Cysteine Proteases; Glyceraldehyde-3-Phosphate Dehydrogenases; Humans; Methyl Methanesulfonate; Oxidation-Reduction; Plant Proteins; Rabbits; Recoverin; Sulfhydryl Compounds; Triticum | 2019 |
Identification of Chemicals Associated Gambusia affinis (Cyprinodontiformes: Poeciliidae), and Their Effect on Oviposition Behavior of Culex tarsalis (Diptera: Culicidae) in the Laboratory.
Topics: Animals; Culex; Cyprinodontiformes; Disulfides; Female; Methyl Methanesulfonate; Oviposition; Sulfides; Volatile Organic Compounds | 2021 |