methyl methanesulfonate has been researched along with o-(6)-methylguanine in 20 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 12 (60.00) | 18.7374 |
| 1990's | 7 (35.00) | 18.2507 |
| 2000's | 1 (5.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Erickson, LC | 1 |
| Ahnström, G; Eizirik, DL; Sandler, S; Welsh, M | 1 |
| Hart, RW; Lipman, JM; Turturro, A | 1 |
| Deininger, C; Eder, E; Wiedenmann, M | 1 |
| Goad, DL; Rebeck, GW; Samson, L; Smith, CM | 1 |
| Hall, J; Karran, P; Kataoka, H; Stephenson, C | 1 |
| Brennand, J; Margison, GP; Ockey, CH; White, GR | 1 |
| Laval, F | 1 |
| Day, RS; DiPaolo, JA; Doniger, J | 1 |
| Abbondandolo, A; Frosina, G | 1 |
| Asbery, LJ; Chandler, PM; Harris, G; Jones, MG; Lawley, PD | 1 |
| Sklar, R; Strauss, B | 1 |
| Becker, Y; Shiloh, Y | 1 |
| Abbondandolo, A; Aprile, A; Arena, G; Bonatti, S; Cavalieri, Z; Pellerano, P; Rocco, M; Sailer, K; Viaggi, S | 1 |
| Cunningham, JM; Delaney, CA; Di Matteo, M; Dunger, A; Green, IC; Green, MH | 1 |
| Dosch, J; Kaina, B | 1 |
| Bailey, JA; Cooper, DP; Deans, B; Elder, RH; Heeran, MC; Jansen, JG; Margison, GP; Mynett, KJ; Rafferty, JA; van Zeeland, AA; Watson, AJ; Weeks, RJ; Wijnhoven, SW; Willington, MA | 1 |
| Glaab, WE; Skopek, TR; Tindall, KR | 1 |
| Brennand, J; Fox, M | 1 |
| Hidaka, M; Komori, K; Lim, TH; Nakatsu, Y; Sanada, M; Sekiguchi, M; Takagi, Y; Tsuzuki, T | 1 |
3 review(s) available for methyl methanesulfonate and o-(6)-methylguanine
| Article | Year |
|---|---|
The role of O-6 methylguanine DNA methyltransferase (MGMT) in drug resistance and strategies for its inhibition.
Topics: Animals; DNA Repair; Drug Resistance; Ethylnitrosourea; Guanine; Humans; Methyl Methanesulfonate; Methylnitronitrosoguanidine; Methyltransferases; Neoplasms; O(6)-Methylguanine-DNA Methyltransferase; Rats; Streptozocin | 1991 |
The influence of dietary restriction on DNA repair in rodents: a preliminary study.
Topics: Animals; DNA; DNA Repair; Energy Intake; Guanine; Methyl Methanesulfonate; Mice; Mice, Inbred Strains; Rats; Rats, Inbred BN; Rats, Inbred F344; Ultraviolet Rays | 1989 |
The current evidence for an adaptive response to alkylating agents in mammalian cells, with special reference to experiments with in vitro cell cultures.
Topics: Alkylating Agents; Animals; Bacterial Proteins; Cell Survival; Cells, Cultured; Chromosome Aberrations; Cricetinae; Cricetulus; DNA Glycosylases; DNA Ligases; DNA Repair; Drug Resistance; Escherichia coli; Guanine; Haplorhini; Kidney; Liver; Mammals; Methyl Methanesulfonate; Methylnitronitrosoguanidine; Methylnitrosourea; Methyltransferases; Mice; Mutation; N-Glycosyl Hydrolases; O(6)-Methylguanine-DNA Methyltransferase; Phenotype; Placenta; Rats | 1985 |
17 other study(ies) available for methyl methanesulfonate and o-(6)-methylguanine
| Article | Year |
|---|---|
Exposure of pancreatic islets to different alkylating agents decreases mitochondrial DNA content but only streptozotocin induces long-lasting functional impairment of B-cells.
Topics: Adenine; Alkylating Agents; Animals; Cytochrome b Group; DNA; Dose-Response Relationship, Drug; Glucagon; Glucose; Guanine; Immunoblotting; Insulin; Islets of Langerhans; Male; Methyl Methanesulfonate; Methylnitrosourea; Mice; Mitochondria; RNA, Messenger; Streptozocin | 1991 |
Methyl methanesulphonate (MMS) is clearly mutagenic in S. typhimurium strain TA1535; a comparison with strain TA100.
Topics: DNA, Bacterial; Guanine; Methyl Methanesulfonate; Mutagenicity Tests; Mutagens; Salmonella typhimurium; Species Specificity | 1989 |
Characterization of the major DNA repair methyltransferase activity in unadapted Escherichia coli and identification of a similar activity in Salmonella typhimurium.
Topics: Cysteine; DNA Repair; Escherichia coli; Guanine; Kinetics; Methyl Methanesulfonate; Methylnitronitrosoguanidine; Methyltransferases; Molecular Weight; O(6)-Methylguanine-DNA Methyltransferase; Salmonella typhimurium | 1989 |
The contribution of O6-methylguanine and methylphosphotriesters to the cytotoxicity of alkylating agents in mammalian cells.
Topics: Alkylating Agents; Animals; Cell Line; Cloning, Molecular; Cricetinae; DNA Damage; DNA Repair; Drug Resistance; Guanine; Methyl Methanesulfonate; Methylation; Methylnitronitrosoguanidine; Methyltransferases; O(6)-Methylguanine-DNA Methyltransferase; Organophosphates; Organophosphorus Compounds; Structure-Activity Relationship; Transfection | 1988 |
Chinese hamster cells harbouring the Escherichia coli O6-alkylguanine alkyltransferase gene are less susceptible to sister chromatid exchange induction and chromosome damage by methylating agents.
Topics: Alkylating Agents; Animals; Cell Line; Chromosome Aberrations; Cricetinae; Cricetulus; Escherichia coli; Guanine; Methyl Methanesulfonate; Methylnitrosourea; Methyltransferases; O(6)-Methylguanine-DNA Methyltransferase; Sister Chromatid Exchange | 1986 |
Adaptive response to alkylating agents in mammalian cells.
Topics: Adaptation, Physiological; Alkylating Agents; Animals; Cell Survival; Guanine; Methyl Methanesulfonate; Methylnitronitrosoguanidine; Methylnitrosourea; Methyltransferases; Mutation; O(6)-Methylguanine-DNA Methyltransferase; Rats | 1986 |
Quantitative assessment of the role of O6-methylguanine in the initiation of carcinogenesis by methylating agents.
Topics: Animals; Cell Transformation, Neoplastic; Cricetinae; DNA; Dose-Response Relationship, Drug; Female; Guanine; Mesocricetus; Methyl Methanesulfonate; Methylation; Methylnitronitrosoguanidine; Methylnitrosourea; Nitrosourea Compounds; Pregnancy | 1985 |
Autoimmune haemolytic disease in mice after exposure to a methylating carcinogen.
Topics: Anemia, Hemolytic, Autoimmune; Animals; DNA; Dose-Response Relationship, Drug; Guanine; Methyl Methanesulfonate; Methylation; Methylnitrosourea; Mice; Mice, Inbred Strains; Neoplasms, Experimental; Nitrosourea Compounds; Species Specificity; Spleen; Thymoma; Thymus Neoplasms | 1983 |
Role of the uvrE gene product and of inducible O6-methylguanine removal in the induction of mutations by N-methyl-N'-nitro-N-nitrosoguanidine in Escherichia coli.
Topics: Chloramphenicol; DNA Repair; DNA, Bacterial; Dose-Response Relationship, Drug; Escherichia coli; Ethyl Methanesulfonate; Guanine; Methyl Methanesulfonate; Methylnitronitrosoguanidine; Mutation; Protein Biosynthesis; Ultraviolet Rays | 1980 |
Kinetics of O6-methylguanine repair in human normal and ataxia telangiectasia cell lines and correlation of repair capacity with cellular sensitivity to methylating agents.
Topics: Adolescent; Adult; Alkylating Agents; Ataxia Telangiectasia; Cell Division; Cells, Cultured; Child; DNA; DNA Repair; Female; Guanine; Humans; Infant, Newborn; Kinetics; Male; Methyl Methanesulfonate; Methylation; Methylnitronitrosoguanidine; Methylnitrosourea | 1981 |
Induction of kinetochore-containing micronuclei by exogenous O6-methylguanine requires conversion of the methylated base to a nucleotide.
Topics: Adenine; Animals; Cell Line; Cricetinae; Cricetulus; Guanine; Hypoxanthine; Hypoxanthine Phosphoribosyltransferase; Hypoxanthines; Kinetochores; Methyl Methanesulfonate; Mice; Micronuclei, Chromosome-Defective; Micronucleus Tests; Mutagens | 1995 |
Comparison of inhibition of glucose-stimulated insulin secretion in rat islets of Langerhans by streptozotocin and methyl and ethyl nitrosoureas and methanesulphonates. Lack of correlation with nitric oxide-releasing or O6-alkylating ability.
Topics: Alkylating Agents; Animals; Cyclic GMP; Ethyl Methanesulfonate; Ethylnitrosourea; Glucose; Guanine; Insulin; Islets of Langerhans; Methyl Methanesulfonate; Methylnitrosourea; Nitric Oxide; Rats; Rats, Sprague-Dawley; Streptozocin; Structure-Activity Relationship | 1995 |
Induction of c-fos, c-jun, junB and junD mRNA and AP-1 by alkylating mutagens in cells deficient and proficient for the DNA repair protein O6-methylguanine-DNA methyltransferase (MGMT) and its relationship to cell death, mutation induction and chromosomal
Topics: Alkylating Agents; Animals; Cell Death; CHO Cells; Chromosome Aberrations; Cricetinae; DNA Repair; Dose-Response Relationship, Drug; Gene Expression Regulation, Neoplastic; Glycoproteins; Guanine; Methyl Methanesulfonate; Methylnitronitrosoguanidine; Methyltransferases; Mutagens; Mutation; O(6)-Methylguanine-DNA Methyltransferase; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Recombination, Genetic; RNA, Messenger; Transcription Factor AP-1; Transfection; Ultraviolet Rays | 1996 |
Alkylpurine-DNA-N-glycosylase knockout mice show increased susceptibility to induction of mutations by methyl methanesulfonate.
Topics: Animals; Bone Marrow Cells; Cells, Cultured; Dacarbazine; DNA Glycosylases; Erythrocytes; Ethylnitrosourea; Female; Fibroblasts; Guanine; Hypoxanthine Phosphoribosyltransferase; Leukocyte Count; Liver; Male; Methyl Methanesulfonate; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Mice, Knockout; Mutagens; Mutation; N-Glycosyl Hydrolases; Temozolomide | 1998 |
Specificity of mutations induced by methyl methanesulfonate in mismatch repair-deficient human cancer cell lines.
Topics: Antineoplastic Agents, Alkylating; Base Pair Mismatch; DNA Repair; Guanine; Humans; Hypoxanthine Phosphoribosyltransferase; Methyl Methanesulfonate; Mutagens; Mutation; O(6)-Methylguanine-DNA Methyltransferase; RNA, Messenger; Sequence Analysis; Tumor Cells, Cultured | 1999 |
Evidence for the involvement of lesions other than O6-alkylguanine in mammalian cell mutagenesis.
Topics: Adenine; Alkylating Agents; Animals; Carcinogens; Cricetinae; DNA; DNA Damage; Drug Resistance; Guanine; Hypoxanthine Phosphoribosyltransferase; Methyl Methanesulfonate; Methylnitrosourea; Mutagenesis; Mutagens; Sulfuric Acid Esters; Thioguanine | 1980 |
A novel protein, MAPO1, that functions in apoptosis triggered by O6-methylguanine mispair in DNA.
Topics: Adaptor Proteins, Signal Transducing; Animals; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; Apoptosis; Base Pair Mismatch; Caspase 3; DNA; DNA Modification Methylases; DNA Repair Enzymes; Etoposide; Fibroblasts; Gene Expression Regulation; Guanine; Humans; Lung; Methyl Methanesulfonate; Methylnitrosourea; Mice; Mice, Knockout; Mutagenesis; Mutation; MutL Protein Homolog 1; Nuclear Proteins; RNA, Small Interfering; Tumor Suppressor Proteins; Ultraviolet Rays | 2009 |