methyl methanesulfonate has been researched along with guanine in 43 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 18 (41.86) | 18.7374 |
| 1990's | 14 (32.56) | 18.2507 |
| 2000's | 10 (23.26) | 29.6817 |
| 2010's | 1 (2.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Frei, JV; Lawley, PD | 1 |
| Huang, PH; Stewart, BW | 1 |
| Kleihues, P; Margison, GP | 1 |
| Gibson, NW; Prakash, AS | 1 |
| Erickson, LC | 1 |
| Ahnström, G; Eizirik, DL; Sandler, S; Welsh, M | 1 |
| Berdal, KG; Bjelland, S; Bjørås, M; Seeberg, E | 1 |
| Hart, RW; Lipman, JM; Turturro, A | 1 |
| Deininger, C; Eder, E; Wiedenmann, M | 1 |
| Goad, DL; Rebeck, GW; Samson, L; Smith, CM | 1 |
| Hall, J; Karran, P; Kataoka, H; Stephenson, C | 1 |
| Brennand, J; Margison, GP; Ockey, CH; White, GR | 1 |
| D'Ambrosio, SM; Wani, AA | 1 |
| Laval, F | 1 |
| Day, RS; DiPaolo, JA; Doniger, J | 1 |
| Abbondandolo, A; Frosina, G | 1 |
| Rajalakshmi, S; Rao, RM; Sarma, DS | 1 |
| Huang, SS; Pontzer, NJ; Shaikh, B | 1 |
| Asbery, LJ; Chandler, PM; Harris, G; Jones, MG; Lawley, PD | 1 |
| Sklar, R; Strauss, B | 1 |
| Becker, Y; Shiloh, Y | 1 |
| Abbondandolo, A; Aprile, A; Arena, G; Bonatti, S; Cavalieri, Z; Pellerano, P; Rocco, M; Sailer, K; Viaggi, S | 1 |
| Bohr, VA; Larminat, F; May, A; Petersen, LN; Pirsel, M; Stevnsner, T | 1 |
| Cunningham, JM; Delaney, CA; Di Matteo, M; Dunger, A; Green, IC; Green, MH | 1 |
| Dosch, J; Kaina, B | 1 |
| Faustman, EM; Seeley, MR | 1 |
| Bailey, JA; Cooper, DP; Deans, B; Elder, RH; Heeran, MC; Jansen, JG; Margison, GP; Mynett, KJ; Rafferty, JA; van Zeeland, AA; Watson, AJ; Weeks, RJ; Wijnhoven, SW; Willington, MA | 1 |
| Berger, MS; Blank, A; Bobola, MS; Silber, JR; Tseng, SH | 1 |
| Dobrzańska, M; Kraszewska, E; Tudek, B | 1 |
| Calléja, F; Jansen, JG; Laval, F; van Zeeland, AA; Vrieling, H | 1 |
| Glaab, WE; Skopek, TR; Tindall, KR | 1 |
| Brennand, J; Fox, M | 1 |
| Cho, HJ; Chung, MH; Hyun, JW; Jeong, HG; Kim, SH; Lee, JS; Lee, KY; Lee, MR; Moon, AR; You, HJ | 1 |
| Fowler, P; Parry, EM; Parry, JM; Quick, E | 1 |
| Connor, EE; Wilson, JJ; Wyatt, MD | 1 |
| Rusling, JF; Tarun, M | 1 |
| Cai, S; Cooper, RJ; Ferkowicz, MJ; Hartwell, JR; Kelley, MR; Pollok, KE; Xu, Y | 1 |
| He, Y; Kelley, MR; Nakamura, J; Pachkowski, BF; Rinne, ML | 1 |
| Martin, EA; O'Donovan, MR; Smith, CC | 1 |
| Brink, A; Lutz, WK; Schulz, B; Stopper, H | 1 |
| Eckardt-Schupp, F; Hematulin, A; Kröger, C; Mörtl, S; Müller, R; Sagan, D | 1 |
| Hidaka, M; Komori, K; Lim, TH; Nakatsu, Y; Sanada, M; Sekiguchi, M; Takagi, Y; Tsuzuki, T | 1 |
| Dusinska, M; Elje, E; Hesler, M; Kohl, Y; Mann, P; Mariussen, E; Rundén-Pran, E; Wagner, S | 1 |
3 review(s) available for methyl methanesulfonate and guanine
| Article | Year |
|---|---|
The role of O-6 methylguanine DNA methyltransferase (MGMT) in drug resistance and strategies for its inhibition.
Topics: Animals; DNA Repair; Drug Resistance; Ethylnitrosourea; Guanine; Humans; Methyl Methanesulfonate; Methylnitronitrosoguanidine; Methyltransferases; Neoplasms; O(6)-Methylguanine-DNA Methyltransferase; Rats; Streptozocin | 1991 |
The influence of dietary restriction on DNA repair in rodents: a preliminary study.
Topics: Animals; DNA; DNA Repair; Energy Intake; Guanine; Methyl Methanesulfonate; Mice; Mice, Inbred Strains; Rats; Rats, Inbred BN; Rats, Inbred F344; Ultraviolet Rays | 1989 |
The current evidence for an adaptive response to alkylating agents in mammalian cells, with special reference to experiments with in vitro cell cultures.
Topics: Alkylating Agents; Animals; Bacterial Proteins; Cell Survival; Cells, Cultured; Chromosome Aberrations; Cricetinae; Cricetulus; DNA Glycosylases; DNA Ligases; DNA Repair; Drug Resistance; Escherichia coli; Guanine; Haplorhini; Kidney; Liver; Mammals; Methyl Methanesulfonate; Methylnitronitrosoguanidine; Methylnitrosourea; Methyltransferases; Mice; Mutation; N-Glycosyl Hydrolases; O(6)-Methylguanine-DNA Methyltransferase; Phenotype; Placenta; Rats | 1985 |
40 other study(ies) available for methyl methanesulfonate and guanine
| Article | Year |
|---|---|
Tissue distribution and mode of DNA methylation in mice by methyl methanesulphonate and N-methyl-N' -nitro-N-nitrosoguanidine: lack of thymic lymphoma induction and low extent of methylation of target tissue DNA at 0-6 of guanine.
Topics: Animals; Carcinogens; DNA; Female; Guanine; Lymphoma; Mesylates; Methyl Methanesulfonate; Methylnitronitrosoguanidine; Mice; Mice, Inbred C57BL; Neoplasms, Experimental; Nitrosoguanidines; Thymus Gland; Thymus Neoplasms | 1976 |
Differences in patterns of structural change by rat liver DNA following administration of dimethylnitrosamine and methyl methanesulfonate.
Topics: Animals; Caffeine; Chromatography; Dimethylnitrosamine; DNA; DNA Repair; Dose-Response Relationship, Drug; Female; Guanine; Liver; Mesylates; Methyl Methanesulfonate; Nitrosamines; Rats | 1977 |
Exhaustion and recovery of repair excision of O6-methylguanine from rat liver DNA.
Topics: Animals; Carcinogens; DNA; DNA Repair; Female; Guanine; Liver; Methyl Methanesulfonate; Methylnitrosourea; Nitrosourea Compounds; Radiation Effects; Rats; Time Factors; X-Rays | 1976 |
Sequence-selective depurination, DNA interstrand cross-linking and DNA strand break formation associated with alkylated DNA.
Topics: Alkylation; Base Sequence; Cross-Linking Reagents; DNA; DNA Damage; Ellagic Acid; Ethylnitrosourea; Guanine; Methyl Methanesulfonate; Molecular Sequence Data; Spermidine | 1992 |
Exposure of pancreatic islets to different alkylating agents decreases mitochondrial DNA content but only streptozotocin induces long-lasting functional impairment of B-cells.
Topics: Adenine; Alkylating Agents; Animals; Cytochrome b Group; DNA; Dose-Response Relationship, Drug; Glucagon; Glucose; Guanine; Immunoblotting; Insulin; Islets of Langerhans; Male; Methyl Methanesulfonate; Methylnitrosourea; Mice; Mitochondria; RNA, Messenger; Streptozocin | 1991 |
Cloning and expression in Escherichia coli of a gene for an alkylbase DNA glycosylase from Saccharomyces cerevisiae; a homologue to the bacterial alkA gene.
Topics: Adenine; Amino Acid Sequence; Base Sequence; Cloning, Molecular; DNA Glycosylases; DNA Repair; Drug Resistance; Escherichia coli; Gene Expression; Genes, Bacterial; Genes, Fungal; Guanine; Methyl Methanesulfonate; Molecular Sequence Data; N-Glycosyl Hydrolases; Open Reading Frames; Restriction Mapping; Saccharomyces cerevisiae; Sequence Homology, Nucleic Acid | 1990 |
Methyl methanesulphonate (MMS) is clearly mutagenic in S. typhimurium strain TA1535; a comparison with strain TA100.
Topics: DNA, Bacterial; Guanine; Methyl Methanesulfonate; Mutagenicity Tests; Mutagens; Salmonella typhimurium; Species Specificity | 1989 |
Characterization of the major DNA repair methyltransferase activity in unadapted Escherichia coli and identification of a similar activity in Salmonella typhimurium.
Topics: Cysteine; DNA Repair; Escherichia coli; Guanine; Kinetics; Methyl Methanesulfonate; Methylnitronitrosoguanidine; Methyltransferases; Molecular Weight; O(6)-Methylguanine-DNA Methyltransferase; Salmonella typhimurium | 1989 |
The contribution of O6-methylguanine and methylphosphotriesters to the cytotoxicity of alkylating agents in mammalian cells.
Topics: Alkylating Agents; Animals; Cell Line; Cloning, Molecular; Cricetinae; DNA Damage; DNA Repair; Drug Resistance; Guanine; Methyl Methanesulfonate; Methylation; Methylnitronitrosoguanidine; Methyltransferases; O(6)-Methylguanine-DNA Methyltransferase; Organophosphates; Organophosphorus Compounds; Structure-Activity Relationship; Transfection | 1988 |
Chinese hamster cells harbouring the Escherichia coli O6-alkylguanine alkyltransferase gene are less susceptible to sister chromatid exchange induction and chromosome damage by methylating agents.
Topics: Alkylating Agents; Animals; Cell Line; Chromosome Aberrations; Cricetinae; Cricetulus; Escherichia coli; Guanine; Methyl Methanesulfonate; Methylnitrosourea; Methyltransferases; O(6)-Methylguanine-DNA Methyltransferase; Sister Chromatid Exchange | 1986 |
Specific DNA alkylation damage and its repair in carcinogen-treated rat liver and brain.
Topics: Adenine; Alkylating Agents; Animals; Brain; Carcinogens; DNA; DNA Repair; Guanine; Hydrogen-Ion Concentration; Hydrolysis; Liver; Male; Methyl Methanesulfonate; Methylnitrosourea; Rats; Rats, Inbred Strains | 1986 |
Adaptive response to alkylating agents in mammalian cells.
Topics: Adaptation, Physiological; Alkylating Agents; Animals; Cell Survival; Guanine; Methyl Methanesulfonate; Methylnitronitrosoguanidine; Methylnitrosourea; Methyltransferases; Mutation; O(6)-Methylguanine-DNA Methyltransferase; Rats | 1986 |
Quantitative assessment of the role of O6-methylguanine in the initiation of carcinogenesis by methylating agents.
Topics: Animals; Cell Transformation, Neoplastic; Cricetinae; DNA; Dose-Response Relationship, Drug; Female; Guanine; Mesocricetus; Methyl Methanesulfonate; Methylation; Methylnitronitrosoguanidine; Methylnitrosourea; Nitrosourea Compounds; Pregnancy | 1985 |
Carcinogen-DNA interaction: differential effects of distamycin-a and spermine on the formation of 7-methylguanine in DNA by N-methyl-N-nitrosourea, methylmethanesulfonate, and dimethylsulfate.
Topics: Animals; Carcinogens; Distamycins; DNA; Drug Interactions; Guanine; Liver; Methyl Methanesulfonate; Methylation; Methylnitrosourea; Pyrroles; Rats; Spermine; Sulfuric Acid Esters | 1980 |
Urinary excretion of methylated purines and 1-methyl-nicotinamide following administration of methylating carcinogens.
Topics: 1,2-Dimethylhydrazine; Adenine; Alkylating Agents; Animals; Carcinogens; Dimethylhydrazines; Dimethylnitrosamine; Guanine; Male; Methyl Methanesulfonate; Methylation; Methylnitronitrosoguanidine; Niacinamide; Rats | 1980 |
Autoimmune haemolytic disease in mice after exposure to a methylating carcinogen.
Topics: Anemia, Hemolytic, Autoimmune; Animals; DNA; Dose-Response Relationship, Drug; Guanine; Methyl Methanesulfonate; Methylation; Methylnitrosourea; Mice; Mice, Inbred Strains; Neoplasms, Experimental; Nitrosourea Compounds; Species Specificity; Spleen; Thymoma; Thymus Neoplasms | 1983 |
Role of the uvrE gene product and of inducible O6-methylguanine removal in the induction of mutations by N-methyl-N'-nitro-N-nitrosoguanidine in Escherichia coli.
Topics: Chloramphenicol; DNA Repair; DNA, Bacterial; Dose-Response Relationship, Drug; Escherichia coli; Ethyl Methanesulfonate; Guanine; Methyl Methanesulfonate; Methylnitronitrosoguanidine; Mutation; Protein Biosynthesis; Ultraviolet Rays | 1980 |
Kinetics of O6-methylguanine repair in human normal and ataxia telangiectasia cell lines and correlation of repair capacity with cellular sensitivity to methylating agents.
Topics: Adolescent; Adult; Alkylating Agents; Ataxia Telangiectasia; Cell Division; Cells, Cultured; Child; DNA; DNA Repair; Female; Guanine; Humans; Infant, Newborn; Kinetics; Male; Methyl Methanesulfonate; Methylation; Methylnitronitrosoguanidine; Methylnitrosourea | 1981 |
Induction of kinetochore-containing micronuclei by exogenous O6-methylguanine requires conversion of the methylated base to a nucleotide.
Topics: Adenine; Animals; Cell Line; Cricetinae; Cricetulus; Guanine; Hypoxanthine; Hypoxanthine Phosphoribosyltransferase; Hypoxanthines; Kinetochores; Methyl Methanesulfonate; Mice; Micronuclei, Chromosome-Defective; Micronucleus Tests; Mutagens | 1995 |
Repair of ribosomal RNA genes in hamster cells after UV irradiation, or treatment with cisplatin or alkylating agents.
Topics: Alkylating Agents; Animals; CHO Cells; Cisplatin; Cricetinae; DNA Damage; DNA Repair; DNA, Ribosomal; Genes; Guanine; Mechlorethamine; Methyl Methanesulfonate; Pyrimidine Dimers; RNA Polymerase I; RNA Polymerase II; RNA, Ribosomal; Tetrahydrofolate Dehydrogenase; Transcription, Genetic; Ultraviolet Rays | 1993 |
Comparison of inhibition of glucose-stimulated insulin secretion in rat islets of Langerhans by streptozotocin and methyl and ethyl nitrosoureas and methanesulphonates. Lack of correlation with nitric oxide-releasing or O6-alkylating ability.
Topics: Alkylating Agents; Animals; Cyclic GMP; Ethyl Methanesulfonate; Ethylnitrosourea; Glucose; Guanine; Insulin; Islets of Langerhans; Methyl Methanesulfonate; Methylnitrosourea; Nitric Oxide; Rats; Rats, Sprague-Dawley; Streptozocin; Structure-Activity Relationship | 1995 |
Induction of c-fos, c-jun, junB and junD mRNA and AP-1 by alkylating mutagens in cells deficient and proficient for the DNA repair protein O6-methylguanine-DNA methyltransferase (MGMT) and its relationship to cell death, mutation induction and chromosomal
Topics: Alkylating Agents; Animals; Cell Death; CHO Cells; Chromosome Aberrations; Cricetinae; DNA Repair; Dose-Response Relationship, Drug; Gene Expression Regulation, Neoplastic; Glycoproteins; Guanine; Methyl Methanesulfonate; Methylnitronitrosoguanidine; Methyltransferases; Mutagens; Mutation; O(6)-Methylguanine-DNA Methyltransferase; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Recombination, Genetic; RNA, Messenger; Transcription Factor AP-1; Transfection; Ultraviolet Rays | 1996 |
Effects of O6-benzylguanine on growth and differentiation of P19 embryonic carcinoma cells treated with alkylating agents.
Topics: Alkylating Agents; Animals; Antineoplastic Agents; Carcinogens; Carcinoma, Embryonal; Cell Differentiation; Cell Division; Cell Survival; DNA Repair; Ethyl Methanesulfonate; Ethylnitrosourea; Guanine; Mesencephalon; Methyl Methanesulfonate; Methylnitrosourea; Mice; Neurons; O(6)-Methylguanine-DNA Methyltransferase; Rats; Tretinoin; Tumor Cells, Cultured | 1998 |
Alkylpurine-DNA-N-glycosylase knockout mice show increased susceptibility to induction of mutations by methyl methanesulfonate.
Topics: Animals; Bone Marrow Cells; Cells, Cultured; Dacarbazine; DNA Glycosylases; Erythrocytes; Ethylnitrosourea; Female; Fibroblasts; Guanine; Hypoxanthine Phosphoribosyltransferase; Leukocyte Count; Liver; Male; Methyl Methanesulfonate; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Mice, Knockout; Mutagens; Mutation; N-Glycosyl Hydrolases; Temozolomide | 1998 |
Role of O6-methylguanine-DNA methyltransferase in resistance of human brain tumor cell lines to the clinically relevant methylating agents temozolomide and streptozotocin.
Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Drug Resistance, Neoplasm; Guanine; Humans; Methyl Methanesulfonate; Methylation; Methylnitronitrosoguanidine; O(6)-Methylguanine-DNA Methyltransferase; Streptozocin; Temozolomide; Tumor Cells, Cultured | 1996 |
Tobacco BY-2 cells excise both 3-methyladenine and 7-methylguanine from methylated DNA.
Topics: Adenine; Animals; Cattle; Cell Line; Chromatography, High Pressure Liquid; DNA; DNA Glycosylases; DNA Methylation; Guanine; Methyl Methanesulfonate; Methylnitrosourea; Mutagens; N-Glycosyl Hydrolases; Nicotiana; Plants, Toxic | 1998 |
Modulation of the toxic and mutagenic effects induced by methyl methanesulfonate in Chinese hamster ovary cells by overexpression of the rat N-alkylpurine-DNA glycosylase.
Topics: Adenine; Alkylating Agents; Animals; Base Pair Mismatch; CHO Cells; Cricetinae; Cricetulus; DNA Damage; DNA Glycosylases; DNA Ligases; DNA Methylation; DNA Repair; Enzyme Induction; Frameshift Mutation; Guanine; Hypoxanthine Phosphoribosyltransferase; Methyl Methanesulfonate; Mutagenesis; Mutagens; N-Glycosyl Hydrolases; Rats; Recombinant Fusion Proteins; Transfection | 1999 |
Specificity of mutations induced by methyl methanesulfonate in mismatch repair-deficient human cancer cell lines.
Topics: Antineoplastic Agents, Alkylating; Base Pair Mismatch; DNA Repair; Guanine; Humans; Hypoxanthine Phosphoribosyltransferase; Methyl Methanesulfonate; Mutagens; Mutation; O(6)-Methylguanine-DNA Methyltransferase; RNA, Messenger; Sequence Analysis; Tumor Cells, Cultured | 1999 |
Evidence for the involvement of lesions other than O6-alkylguanine in mammalian cell mutagenesis.
Topics: Adenine; Alkylating Agents; Animals; Carcinogens; Cricetinae; DNA; DNA Damage; Drug Resistance; Guanine; Hypoxanthine Phosphoribosyltransferase; Methyl Methanesulfonate; Methylnitrosourea; Mutagenesis; Mutagens; Sulfuric Acid Esters; Thioguanine | 1980 |
Transcription factors NF-YA regulate the induction of human OGG1 following DNA-alkylating agent methylmethane sulfonate (MMS) treatment.
Topics: Adjuvants, Immunologic; Alkylating Agents; Amino Acid Motifs; Antineoplastic Agents, Alkylating; Blotting, Western; CCAAT-Binding Factor; Cell Line, Tumor; Cell Nucleus; Cell Survival; DNA; DNA Glycosylases; DNA Repair; Dose-Response Relationship, Drug; Gene Expression Regulation, Neoplastic; Guanine; Guanosine; Humans; Hydrogen Peroxide; Luciferases; Methyl Methanesulfonate; Mutagenesis, Site-Directed; Mutation; Plasmids; Protein Binding; Reverse Transcriptase Polymerase Chain Reaction; Time Factors; Transcription Factors; Transfection; Up-Regulation | 2004 |
Investigations into the biological relevance of in vitro clastogenic and aneugenic activity.
Topics: Alkylating Agents; Amsacrine; Aneuploidy; Cells, Cultured; Chromosome Aberrations; Chromosomes, Human; Cytochalasin B; DNA Damage; Dose-Response Relationship, Drug; Enzyme Inhibitors; Etoposide; Gene Expression Profiling; Guanine; Humans; Lymphocytes; Methyl Methanesulfonate; Micronucleus Tests; Mutagens; Oxyquinoline; Risk; Topoisomerase II Inhibitors | 2004 |
Effects of substrate specificity on initiating the base excision repair of N-methylpurines by variant human 3-methyladenine DNA glycosylases.
Topics: Adenine; Animals; DNA Damage; DNA Glycosylases; DNA Repair; Dose-Response Relationship, Drug; Genetic Engineering; Guanine; Humans; Methyl Methanesulfonate; Mutagens; Saccharomyces cerevisiae; Substrate Specificity | 2005 |
Quantitative measurement of DNA adducts using neutral hydrolysis and LC-MS. Validation of genotoxicity sensors.
Topics: Chromatography, Liquid; DNA; DNA Adducts; DNA Damage; Electrochemistry; Epoxy Compounds; Guanine; Hydrogen-Ion Concentration; Hydrolysis; Methyl Methanesulfonate; Mutagenicity Tests; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization | 2005 |
Mitochondrial targeting of human O6-methylguanine DNA methyltransferase protects against cell killing by chemotherapeutic alkylating agents.
Topics: Antigens, CD34; Antineoplastic Agents, Alkylating; Carmustine; Cell Death; Cell Nucleus; Dacarbazine; DNA Damage; DNA Repair; Drug Resistance, Neoplasm; Guanine; Hematopoietic Stem Cells; Humans; K562 Cells; Methyl Methanesulfonate; Mitochondria; O(6)-Methylguanine-DNA Methyltransferase; Temozolomide; Transfection | 2005 |
N-methylpurine DNA glycosylase overexpression increases alkylation sensitivity by rapidly removing non-toxic 7-methylguanine adducts.
Topics: Alkylating Agents; Cell Line, Tumor; DNA Adducts; DNA Damage; DNA Glycosylases; Gene Expression; Guanine; Humans; Kinetics; Methyl Methanesulfonate | 2005 |
hOGG1 recognizes oxidative damage using the comet assay with greater specificity than FPG or ENDOIII.
Topics: Animals; Bromates; Comet Assay; Deoxyribonuclease (Pyrimidine Dimer); Dimethyl Sulfoxide; DNA Damage; DNA Glycosylases; DNA Repair Enzymes; DNA-Formamidopyrimidine Glycosylase; Escherichia coli Proteins; Ethylnitrosourea; Gamma Rays; Guanine; Humans; Leukemia L5178; Methyl Methanesulfonate; Mice; Oxidation-Reduction; Sensitivity and Specificity | 2006 |
Biological significance of DNA adducts investigated by simultaneous analysis of different endpoints of genotoxicity in L5178Y mouse lymphoma cells treated with methyl methanesulfonate.
Topics: Animals; Cell Line, Tumor; Chromatography, Liquid; Deoxyguanosine; DNA Adducts; DNA Breaks; DNA Methylation; Dose-Response Relationship, Drug; Guanine; Leukemia L5178; Methyl Methanesulfonate; Mice; Models, Biological; Mutagens; Tandem Mass Spectrometry | 2007 |
The DNA repair protein NBS1 influences the base excision repair pathway.
Topics: Alkylation; Cell Cycle Proteins; Cell Survival; Cells, Cultured; DNA Breaks, Double-Stranded; DNA Damage; DNA Repair; Genomic Instability; Guanine; Humans; Hydrogen Peroxide; Methyl Methanesulfonate; Nuclear Proteins; Oxidative Stress; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerases; Signal Transduction; Uracil | 2009 |
A novel protein, MAPO1, that functions in apoptosis triggered by O6-methylguanine mispair in DNA.
Topics: Adaptor Proteins, Signal Transducing; Animals; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; Apoptosis; Base Pair Mismatch; Caspase 3; DNA; DNA Modification Methylases; DNA Repair Enzymes; Etoposide; Fibroblasts; Gene Expression Regulation; Guanine; Humans; Lung; Methyl Methanesulfonate; Methylnitrosourea; Mice; Mice, Knockout; Mutagenesis; Mutation; MutL Protein Homolog 1; Nuclear Proteins; RNA, Small Interfering; Tumor Suppressor Proteins; Ultraviolet Rays | 2009 |
The comet assay applied to HepG2 liver spheroids.
Topics: Cell Culture Techniques; Cell Survival; Chlorpromazine; Colchicine; Comet Assay; DNA Damage; DNA, Neoplasm; Guanine; Hep G2 Cells; Humans; Hydrogen Peroxide; Laboratory Proficiency Testing; Methyl Methanesulfonate; Sensitivity and Specificity; Spheroids, Cellular | 2019 |