methyl methanesulfonate has been researched along with cysteine in 62 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 16 (25.81) | 18.7374 |
| 1990's | 25 (40.32) | 18.2507 |
| 2000's | 16 (25.81) | 29.6817 |
| 2010's | 5 (8.06) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Dunlap, RB; Lewis, CA; Munroe, WA | 1 |
| Bloxham, DP; Sharma, RP; Wilton, DC | 1 |
| Rosin, MP; Stich, HF | 1 |
| Hatanaka, Y; Hikichi, K; Ishibashi, T; Kumazaki, T; Nishi, S; Nishihira, J; Sakai, M; Tsuda, S | 1 |
| Chakraborti, PK; Garabedian, MJ; Simons, SS; Yamamoto, KR | 1 |
| Atkinson, T; Gore, MG; Scawen, MD; Spencer, P | 1 |
| Hutchison, KA; Matić, G; Meshinchi, S; Pratt, WB | 1 |
| Pardo, JP; Slayman, CW | 1 |
| Goad, DL; Rebeck, GW; Samson, L; Smith, CM | 1 |
| Bloxham, DP; Salam, WH | 1 |
| Anderson, PM; Fuchs, JA; Johnson, WV; Korte, JJ; Sung, YC; Xiong, XF | 1 |
| Daly, TJ; Matthews, KS; Olson, JS | 1 |
| Evelo, CT; Henderson, PT; Niessen, HJ; Roelofs, HM | 1 |
| Ballou, DP; Lewis, SD; Olson, ST; Roberts, DD; Shafer, JA | 1 |
| Smith, S; Witkowski, A | 1 |
| Franson, RC; Kyger, EM | 1 |
| Rubluo, A | 1 |
| Bailey, E; Connors, TA; Farmer, PB; Gorf, SM; Rickard, J | 1 |
| Bloxham, DP | 1 |
| Bailey, E; Connors, TA; Farmer, PB; Lamb, JH | 1 |
| Jensen, PE; Shanbhag, VP; Stigbrand, T | 1 |
| Guerra, G; Pardo, JP; Uribe, S | 1 |
| Blättler, WA; Collinson, AR; Singh, R | 1 |
| Pratt, WB; Simons, SS | 1 |
| Hendrickson, TL; Imperiali, B; Pathak, R | 1 |
| Cane, DE; Fitzsimons, BC; Hohn, TM; Shim, JH; Xue, Q | 1 |
| Cavanaugh, AH; Chakraborti, PK; Modarress, KJ; Simons, SS | 1 |
| Harris, KA; Jaffe, EK; Markham, GD; Myers, CB; Volin, M | 1 |
| Kimura, T; Sawai, T; Yamaguchi, A | 1 |
| Jurman, ME; Liu, Y; Yellen, G | 1 |
| Couette, B; Fagart, J; Rafestin-Oblin, ME; Souque, A | 1 |
| Patel, MA; Salleh, HM; Woodard, RW | 1 |
| Matsuo, T; Nakamura, Y; Nakamura, YK; Shimoi, K; Tomita, I | 1 |
| Kimura, T; Sawai, T; Shiina, Y; Yamaguchi, A | 1 |
| Berliner, LJ; Narayan, M | 1 |
| Ikeda, Y; Noguchi, T | 1 |
| Cabrera, N; Garza-Ramos, G; Gómez-Puyou, A; Ostoa-Saloma, P; Pérez-Montfort, R; Saavedra-Lira, E; Tuena de Gómez-Puyou, M | 1 |
| Ha, JH; Loh, SN | 1 |
| Barnes, MH; Brown, NC; Leo, CJ | 1 |
| Alcántara, GH; de Gómez-Puyou, MT; Gao, XG; Garza-Ramos, G; Gómez-Puyou, A; Maldonado, E; Pérez-Montfort, R; Reyes-Vivas, H | 1 |
| Ho, CK; Schwer, B; Shuman, S; Sriskanda, V | 1 |
| Goto, S; Hashimoto, M; Hatanaka, T; Majima, E; Onishi, M; Shinohara, Y; Terada, H | 1 |
| Bravo, DT; Keller, JE; Parsons, SM | 1 |
| Biber, J; Forster, IC; Lambert, G; Murer, H | 1 |
| Cabrera, N; de Gómez-Puyou, MT; Gómez-Puyou, A; Hernández-Alcantara, G; López-Velazquez, G; Pérez-Montfort, R; Reyes-Vivas, H | 1 |
| Loussouarn, G; Masia, R; Nichols, CG; Phillips, LR; Rose, T | 1 |
| Alam, SL; Butler, MC; Feng, Z; Loh, SN | 1 |
| Gordon, DJ; Gupta, V; Makinen, MW; Mustafi, D; Sosa-Peinado, A | 1 |
| Britto, PJ; Knipling, L; McPhie, P; Wolff, J | 1 |
| González-Segura, L; Mújica-Jiménez, C; Muñoz-Clares, RA; Velasco-García, R; Zaldívar-Machorro, VJ | 1 |
| Aguirre-López, B; de Gómez-Puyou, MT; Gómez-Puyou, A; Hernández-Alcántara, G; Pérez-Montfort, R; Zomosa-Signoret, V | 1 |
| Ciarimboli, G; Gorboulev, V; Gorbunov, D; Keller, T; Koepsell, H; Schlachtbauer, P; Schmitt, BM; Sturm, A; Volk, C | 1 |
| Ruf, W; Versteeg, HH | 1 |
| Bhattacharyya, J; Enkvetchakul, D; Jeliazkova, I; Nichols, CG | 1 |
| Carvajal, K; De la Mora-De la Mora, I; Enriquez-Flores, S; Gutierrez-Castrellon, P; Hernandez-Alcantara, G; Lopez-Velazquez, G; Reyes-Vivas, H; Rodriguez-Romero, A | 1 |
| Azam, S; Jilani, A; Jouvet, N; Ramotar, D; Vongsamphanh, R; Yang, S; Yang, X | 1 |
| Gardonio, D; Siemann, S | 1 |
| Dasgupta, A; Jha, SK; Malhotra, P; Udgaonkar, JB | 1 |
| Harris, RA; Howard, RJ; Johnson, WD; Trudell, JR | 1 |
| Czajkowski, C; Ghosh, B; Satyshur, KA | 1 |
| Bechtold, E; Furdui, CM; King, SB; Poole, LB; Reisz, JA | 1 |
| Chan, CK; Chan, HW; Chan, W; Chung, PY; Ham, YH; Jin, L; Wong, YL | 1 |
62 other study(ies) available for methyl methanesulfonate and cysteine
| Article | Year |
|---|---|
Kinetics of sulfhydryl group modification of thymidylate synthetase: a proposal for activation of catalytic cysteinly residues.
Topics: Binding Sites; Cysteine; Dithionitrobenzoic Acid; Hydrogen-Ion Concentration; Kinetics; Lacticaseibacillus casei; Methyl Methanesulfonate; Methyltransferases; Thymidylate Synthase | 1978 |
A detailed investigation of the properties of lactate dehydrogenase in which the 'Essential' cysteine-165 is modified by thioalkylation.
Topics: Alkylation; Binding Sites; Butyrates; Cysteine; Glyoxylates; Hydrogen-Ion Concentration; Kinetics; L-Lactate Dehydrogenase; Methyl Methanesulfonate; NAD; Protein Conformation; Pyruvates; Thiosulfonic Acids | 1979 |
The inhibitory effect of cysteine on the mutagenic activities of several carcinogens.
Topics: 2-Acetylaminofluorene; 4-Nitroquinoline-1-oxide; Acrylamides; Aflatoxins; Carcinogens; Cysteine; Genetic Techniques; Histidine; Methyl Methanesulfonate; Methylnitronitrosoguanidine; Microsomes, Liver; Mutagens; Salmonella typhimurium; Semicarbazones | 1978 |
Characterization of cysteine residues of glutathione S-transferase P: evidence for steric hindrance of substrate binding by a bulky adduct to cysteine 47.
Topics: Amino Acid Sequence; Base Sequence; Binding Sites; Carbon Isotopes; Cloning, Molecular; Cysteine; Escherichia coli; Glutathione Transferase; Isoenzymes; Kinetics; Magnetic Resonance Spectroscopy; Methyl Methanesulfonate; Molecular Sequence Data; Mutagenesis, Site-Directed; Oligodeoxyribonucleotides; Oxadiazoles; Peptide Fragments; Protein Binding; Protein Conformation; Recombinant Proteins | 1992 |
Role of cysteines 640, 656, and 661 in steroid binding to rat glucocorticoid receptors.
Topics: Affinity Labels; Animals; Arsenic; Arsenites; Base Sequence; Blotting, Western; Cysteine; Dexamethasone; Electrophoresis, Polyacrylamide Gel; Heat-Shock Proteins; Methyl Methanesulfonate; Molecular Sequence Data; Mutation; Peptide Fragments; Rats; Receptors, Glucocorticoid; Steroids; Substrate Specificity; Transfection | 1992 |
The identification of a structurally important cysteine residue in the glycerol dehydrogenase from Bacillus stearothermophilus.
Topics: Chemical Phenomena; Chemistry; Chromatography, High Pressure Liquid; Cobalt; Cysteine; Diethyl Pyrocarbonate; Dithionitrobenzoic Acid; Geobacillus stearothermophilus; Histidine; Iodoacetates; Iodoacetic Acid; Kinetics; Macromolecular Substances; Methyl Methanesulfonate; Molecular Weight; Peptide Fragments; Sugar Alcohol Dehydrogenases; Tritium; Trypsin; Zinc | 1991 |
Selective molybdate-directed covalent modification of sulfhydryl groups in the steroid-binding versus the DNA-binding domain of the glucocorticoid receptor.
Topics: Affinity Labels; Animals; Binding Sites; Cysteine; Cytosol; Dexamethasone; DNA-Binding Proteins; Ethylmaleimide; Hydrogen Peroxide; Kinetics; L Cells; Methyl Methanesulfonate; Mice; Molecular Weight; Molybdenum; Receptors, Glucocorticoid; Sulfhydryl Compounds; Sulfhydryl Reagents | 1990 |
Cysteine 532 and cysteine 545 are the N-ethylmaleimide-reactive residues of the Neurospora plasma membrane H+-ATPase.
Topics: Amino Acid Sequence; Animals; Binding Sites; Cysteine; Cytoplasm; Ethylmaleimide; Fungal Proteins; Methyl Methanesulfonate; Molecular Sequence Data; Naphthalenesulfonates; Neurospora; Neurospora crassa; Peptide Fragments; Proton-Translocating ATPases; Rabbits; Rats; Sequence Homology, Nucleic Acid; Sheep; Swine | 1989 |
Characterization of the major DNA repair methyltransferase activity in unadapted Escherichia coli and identification of a similar activity in Salmonella typhimurium.
Topics: Cysteine; DNA Repair; Escherichia coli; Guanine; Kinetics; Methyl Methanesulfonate; Methylnitronitrosoguanidine; Methyltransferases; Molecular Weight; O(6)-Methylguanine-DNA Methyltransferase; Salmonella typhimurium | 1989 |
Identification of subsidiary catalytic groups at the active site of beta-ketoacyl-CoA thiolase by covalent modification of the protein.
Topics: Acetyl Coenzyme A; Acetyl-CoA C-Acetyltransferase; Acetyltransferases; Acyl Coenzyme A; Amines; Anhydrides; Animals; Binding Sites; Catalysis; Cysteine; Cytosol; Hydrogen-Ion Concentration; Liver; Methyl Methanesulfonate; Rats; Sulfhydryl Compounds; Swine | 1986 |
Reversible dissociation of active octamer of cyanase to inactive dimer promoted by alteration of the sulfhydryl group.
Topics: Aminohydrolases; Azides; Bicarbonates; Carbon-Nitrogen Lyases; Chromatography, Gel; Cysteine; Enzyme Activation; Enzyme Reactivators; Escherichia coli; Ethylmaleimide; Macromolecular Substances; Mercuric Chloride; Methyl Methanesulfonate; Mutation; Oxalates; Oxalic Acid; Serine; Spectrometry, Fluorescence; Structure-Activity Relationship; Sulfhydryl Compounds; Tetranitromethane | 1988 |
Formation of mixed disulfide adducts at cysteine-281 of the lactose repressor protein affects operator and inducer binding parameters.
Topics: Cysteine; Cystine; Dansyl Compounds; Disulfides; Dithionitrobenzoic Acid; Escherichia coli; Isopropyl Thiogalactoside; Kinetics; Methyl Methanesulfonate; Nitrobenzoates; Operator Regions, Genetic; Protein Binding; Repressor Proteins; Transcription Factors | 1986 |
Cysteine adducts of human haemoglobin measured by isoelectric focusing in polyacrylamide gels with a non-linear pH gradient.
Topics: Alkylation; Cysteine; Hemoglobins; Humans; Hydrogen-Ion Concentration; Isoelectric Focusing; Methyl Methanesulfonate | 1987 |
Reactivity of small thiolate anions and cysteine-25 in papain toward methyl methanethiosulfonate.
Topics: Anions; Cysteine; Histidine; Hydrogen-Ion Concentration; Kinetics; Malates; Mathematics; Methyl Methanesulfonate; Papain; Protein Binding; Sulfhydryl Compounds | 1986 |
Inhibition of the functional interaction between fatty acid synthetase and thioesterase II by modification of a single cysteine thiol on the thioesterase.
Topics: Animals; Binding Sites; Chemical Phenomena; Chemistry; Cysteine; Dithionitrobenzoic Acid; Fatty Acid Synthases; Female; Hydrolysis; Kinetics; Methyl Methanesulfonate; Protein Binding; Rats; Sulfhydryl Compounds; Thiolester Hydrolases | 1985 |
Nonspecific inhibition of enzymes by p-bromophenacyl bromide. Inhibition of human platelet phospholipase C and modification of sulfhydryl groups.
Topics: Acetophenones; Blood Platelets; Cysteine; Cytosol; Dithionitrobenzoic Acid; Humans; Kinetics; Methyl Methanesulfonate; Phospholipases; Sulfhydryl Compounds; Type C Phospholipases | 1984 |
The effect of L-cysteine on presoaked barley seeds treated with methyl methanesulfonate.
Topics: Cysteine; Hordeum; Methyl Methanesulfonate; Mutation; Plants | 1982 |
Methylation of cysteine in hemoglobin following exposure to methylating agents.
Topics: Alkylating Agents; Animals; Chemical Phenomena; Chemistry; Cricetinae; Cysteine; Dacarbazine; Dimethylnitrosamine; Dose-Response Relationship, Drug; Environmental Exposure; Gas Chromatography-Mass Spectrometry; Guinea Pigs; Hemoglobins; Humans; Methyl Methanesulfonate; Methylation; Mice; Poultry; Rats; Species Specificity | 1981 |
The chemical reactivity of the histidine-195 residue in lactate dehydrogenase thiomethylated at the cysteine-165 residue.
Topics: Binding Sites; Chemical Phenomena; Chemistry; Cysteine; Diethyl Pyrocarbonate; Formates; Histidine; Hydrogen-Ion Concentration; Kinetics; L-Lactate Dehydrogenase; Ligands; Methyl Methanesulfonate; Pyruvates; Sulfides | 1981 |
Approach to the quantitation of alkylated amino acids in haemoglobin by gas chromatography mass spectrometry.
Topics: Alkylating Agents; Alkylation; Amino Acids; Animals; Carcinogens; Chemical Phenomena; Chemistry; Cysteine; Gas Chromatography-Mass Spectrometry; Hemoglobins; Methyl Methanesulfonate; Rats | 1980 |
Methanethiolation of the liberated cysteine residues of human alpha 2-macroglobulin treated with methylamine generates a derivative with similar functional characteristics as native alpha 2-macroglobulin.
Topics: alpha-Macroglobulins; Animals; Binding Sites; Cysteine; Drug Stability; Humans; In Vitro Techniques; Methyl Methanesulfonate; Methylamines; Mice; Molecular Structure; Sulfhydryl Reagents; Trypsin | 1995 |
Reactivity of the H(+)-ATPase from Kluyveromyces lactis to sulfhydryl reagents.
Topics: Adenosine Diphosphate; Binding Sites; Cell Membrane; Cysteine; Ethylmaleimide; Kinetics; Kluyveromyces; Magnesium Sulfate; Methyl Methanesulfonate; Proton-Translocating ATPases | 1995 |
Assay for thiols based on reactivation of papain.
Topics: Animals; Binding Sites; Cysteine; Disulfides; Dithionitrobenzoic Acid; Edetic Acid; Fabaceae; Fructose-Bisphosphate Aldolase; Indicators and Reagents; Kinetics; Methyl Methanesulfonate; Muscle, Skeletal; Oxidation-Reduction; Papain; Plants, Medicinal; Proteins; Rabbits; Sensitivity and Specificity; Serum Albumin, Bovine; Spectrophotometry; Sulfhydryl Compounds; Urease | 1995 |
Glucocorticoid receptor thiols and steroid-binding activity.
Topics: Affinity Labels; Amino Acid Sequence; Animals; Binding Sites; Chymotrypsin; Cysteine; DNA-Binding Proteins; HSP90 Heat-Shock Proteins; Kinetics; Liver; Methyl Methanesulfonate; Models, Structural; Mutagenesis, Site-Directed; Peptide Fragments; Protein Conformation; Rats; Receptors, Glucocorticoid; Recombinant Proteins; Steroids; Sulfhydryl Compounds; Sulfhydryl Reagents; Thioredoxins; Trypsin | 1995 |
Sulfhydryl modification of the yeast Wbp1p inhibits oligosaccharyl transferase activity.
Topics: Amino Acid Sequence; Biotin; Carbohydrate Sequence; Catalysis; Cysteine; Dithiothreitol; Enzyme Stability; Hexosyltransferases; Kinetics; Macromolecular Substances; Membrane Proteins; Mesylates; Methyl Methanesulfonate; Microsomes; Molecular Sequence Data; Polyisoprenyl Phosphate Oligosaccharides; Saccharomyces cerevisiae; Structure-Activity Relationship; Sulfhydryl Compounds; Transferases | 1995 |
Trichodiene synthase. Identification of active site residues by site-directed mutagenesis.
Topics: Amino Acid Sequence; Base Sequence; Binding Sites; Carbon-Carbon Lyases; Catalysis; Cloning, Molecular; Cysteine; DNA Primers; DNA, Fungal; Escherichia coli; Fusarium; Kinetics; Lyases; Methyl Methanesulfonate; Molecular Sequence Data; Molecular Structure; Mutagenesis, Site-Directed; Polyisoprenyl Phosphates; Sesquiterpenes; Substrate Specificity | 1995 |
Metal oxyanion stabilization of the rat glucocorticoid receptor is independent of thiols.
Topics: Affinity Labels; Animals; Anions; Base Sequence; Cyclic GMP; Cysteine; Dexamethasone; Methyl Methanesulfonate; Molecular Sequence Data; Molybdenum; Mutation; Peptide Fragments; Rats; Receptors, Glucocorticoid; Structure-Activity Relationship; Sulfhydryl Compounds; Trypsin; Tungsten Compounds; Vanadates | 1994 |
Spatial proximity and sequence localization of the reactive sulfhydryls of porphobilinogen synthase.
Topics: Amino Acid Sequence; Animals; Cattle; Cysteine; Electron Spin Resonance Spectroscopy; Methyl Methanesulfonate; Molecular Sequence Data; Molecular Structure; Peptide Mapping; Porphobilinogen Synthase; Spin Labels; Sulfhydryl Compounds | 1993 |
Effects of sulfhydryl reagents on the Cys65 mutant of the transposon Tn10-encoded metal-tetracycline/H+ antiporter of Escherichia coli.
Topics: Amino Acid Sequence; Antiporters; Aspartic Acid; Bacterial Proteins; Carrier Proteins; Cysteine; DNA Transposable Elements; Escherichia coli; Ethylmaleimide; Methyl Methanesulfonate; Models, Molecular; Molecular Sequence Data; Mutation; Protein Conformation; Repressor Proteins; Structure-Activity Relationship; Sulfhydryl Reagents; Tetracycline; Tetracycline Resistance | 1993 |
Dynamic rearrangement of the outer mouth of a K+ channel during gating.
Topics: Cell Line; Cross-Linking Reagents; Cysteine; Dithiothreitol; Electric Conductivity; Embryo, Mammalian; Humans; Ion Channel Gating; Kidney; Macromolecular Substances; Membrane Potentials; Methyl Methanesulfonate; Mutagenesis, Site-Directed; Potassium Channels; Protein Conformation; Structure-Activity Relationship; Transfection | 1996 |
Sulfhydryl groups are involved in the binding of agonists and antagonists to the human mineralocorticoid receptor.
Topics: Aldosterone; Cell-Free System; Cysteine; Humans; Kinetics; Methyl Methanesulfonate; Mineralocorticoid Receptor Antagonists; Mineralocorticoids; Protein Binding; Receptors, Mineralocorticoid; Recombinant Proteins; Spironolactone; Sulfhydryl Reagents | 1996 |
Essential cysteines in 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase from Escherichia coli: analysis by chemical modification and site-directed mutagenesis.
Topics: Aldehyde-Lyases; Base Sequence; Binding Sites; Cysteine; Dithionitrobenzoic Acid; Enzyme Inhibitors; Escherichia coli; Methyl Methanesulfonate; Molecular Sequence Data; Pentosephosphates; Phosphoenolpyruvate; Recombinant Proteins; Structure-Activity Relationship; Sulfhydryl Reagents | 1996 |
S-methyl methanethiosulfonate, bio-antimutagen in homogenates of Cruciferae and Liliaceae vegetables.
Topics: Antimutagenic Agents; Brassica; Cysteine; Hydrogen-Ion Concentration; Methyl Methanesulfonate; Mutagenicity Tests; Vegetables | 1996 |
Cysteine-scanning mutagenesis around transmembrane segment III of Tn10-encoded metal-tetracycline/H+ antiporter.
Topics: Amino Acid Sequence; Antiporters; Bacterial Proteins; Biological Transport; Cysteine; DNA Transposable Elements; Ethylmaleimide; Metals; Methyl Methanesulfonate; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Structure, Secondary; Protons; Sulfhydryl Reagents; Tetracyclines | 1998 |
Mapping fatty acid binding to beta-lactoglobulin: Ligand binding is restricted by modification of Cys 121.
Topics: Anilino Naphthalenesulfonates; Animals; Binding Sites; Cattle; Cyclic N-Oxides; Cysteine; Electron Spin Resonance Spectroscopy; Fluorescence; Fluorescent Dyes; Hydrogen-Ion Concentration; Lactoglobulins; Ligands; Methyl Methanesulfonate; Methylation; Models, Molecular; Molecular Structure; Palmitic Acid; Protein Binding; Spin Labels; Vitamin A | 1998 |
Allosteric regulation of pyruvate kinase M2 isozyme involves a cysteine residue in the intersubunit contact.
Topics: Allosteric Regulation; Amino Acid Sequence; Animals; Cell Line; Cysteine; Enzyme Activation; Isoenzymes; Kinetics; Methyl Methanesulfonate; Molecular Sequence Data; Mutagenesis, Site-Directed; Pyruvate Kinase; Rats; Sequence Homology, Amino Acid; Spodoptera | 1998 |
Sulfhydryl reagent susceptibility in proteins with high sequence similarity--triosephosphate isomerase from Trypanosoma brucei, Trypanosoma cruzi and Leishmania mexicana.
Topics: Animals; Cysteine; Dithionitrobenzoic Acid; Kinetics; Leishmania mexicana; Methyl Methanesulfonate; Mutagenesis, Site-Directed; Polymerase Chain Reaction; Protein Conformation; Recombinant Proteins; Sulfhydryl Reagents; Triose-Phosphate Isomerase; Trypanosoma brucei brucei; Trypanosoma cruzi | 1998 |
Changes in side chain packing during apomyoglobin folding characterized by pulsed thiol-disulfide exchange.
Topics: Amino Acids, Sulfur; Apoproteins; Cysteine; Cystine; Disulfides; Dithionitrobenzoic Acid; Flow Injection Analysis; Kinetics; Methyl Methanesulfonate; Models, Chemical; Models, Molecular; Mutagenesis, Site-Directed; Myoglobin; Protein Denaturation; Protein Engineering; Protein Folding; Spectrometry, Fluorescence; Sulfhydryl Compounds; Sulfhydryl Reagents | 1998 |
DNA polymerase III of Gram-positive eubacteria is a zinc metalloprotein conserving an essential finger-like domain.
Topics: Amino Acid Sequence; Bacillus subtilis; Binding Sites; Catalysis; Conserved Sequence; Cysteine; DNA Polymerase III; Electrons; Gram-Positive Bacteria; Histidine; Iron; Metalloendopeptidases; Methyl Methanesulfonate; Molecular Sequence Data; Point Mutation; Protein Structure, Tertiary; Recombinant Proteins; Zinc Fingers; Zinc Radioisotopes | 1998 |
Derivatization of the interface cysteine of triosephosphate isomerase from Trypanosoma brucei and Trypanosoma cruzi as probe of the interrelationship between the catalytic sites and the dimer interface.
Topics: Animals; Catalysis; Cysteine; Dimerization; Dithionitrobenzoic Acid; Enzyme Activation; Enzyme Inhibitors; Glyceraldehyde 3-Phosphate; Glycolates; Methyl Methanesulfonate; Mutagenesis, Site-Directed; Serine; Substrate Specificity; Sulfhydryl Reagents; Triose-Phosphate Isomerase; Trypanosoma brucei brucei; Trypanosoma cruzi | 1999 |
Mutational analysis of Escherichia coli DNA ligase identifies amino acids required for nick-ligation in vitro and for in vivo complementation of the growth of yeast cells deleted for CDC9 and LIG4.
Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Conserved Sequence; Cysteine; DNA Ligase ATP; DNA Ligases; DNA Mutational Analysis; DNA Repair; Escherichia coli; Genetic Complementation Test; Ligases; Methyl Methanesulfonate; Molecular Sequence Data; Mutagens; Saccharomyces cerevisiae; Structure-Activity Relationship; Ultraviolet Rays; Viral Proteins | 1999 |
Irreversible extrusion of the first loop facing the matrix of the bovine heart mitochondrial ADP/ATP carrier by labeling the Cys(56) residue with the SH-reagent methyl methanethiosulfonate.
Topics: Adenosine Diphosphate; Animals; Cattle; Cross-Linking Reagents; Cysteine; Dose-Response Relationship, Drug; Methyl Methanesulfonate; Mitochondria, Heart; Mitochondrial ADP, ATP Translocases; Models, Chemical; Phenanthrolines; Protein Conformation; Protein Structure, Tertiary; Sulfhydryl Reagents; Time Factors | 2000 |
Modification of cysteines reveals linkage to acetylcholine and vesamicol binding sites in the vesicular acetylcholine transporter of Torpedo californica.
Topics: 4-Chloromercuribenzenesulfonate; Acetylcholine; Amino Acid Sequence; Animals; Base Sequence; Binding Sites; Binding, Competitive; Carrier Proteins; Cysteine; Cytoplasm; Dose-Response Relationship, Drug; Glutathione; Membrane Transport Proteins; Methyl Methanesulfonate; Methylmercury Compounds; Molecular Sequence Data; Neuromuscular Depolarizing Agents; Organomercury Compounds; Phenylmercury Compounds; Piperidines; Protein Structure, Tertiary; Torpedo; Vesicular Acetylcholine Transport Proteins; Vesicular Transport Proteins | 2000 |
Cysteine residues and the structure of the rat renal proximal tubular type II sodium phosphate cotransporter (rat NaPi IIa).
Topics: Amino Acid Sequence; Amino Acid Substitution; Animals; Carrier Proteins; Cysteine; Disulfides; Ethyl Methanesulfonate; Kidney Tubules, Proximal; Mesylates; Methyl Methanesulfonate; Molecular Sequence Data; Mutagenesis, Site-Directed; Oocytes; Protein Structure, Tertiary; Rats; Reducing Agents; Serine; Sodium-Phosphate Cotransporter Proteins; Sodium-Phosphate Cotransporter Proteins, Type II; Sodium-Phosphate Cotransporter Proteins, Type IIa; Symporters; Xenopus laevis | 2000 |
Factors that control the reactivity of the interface cysteine of triosephosphate isomerase from Trypanosoma brucei and Trypanosoma cruzi.
Topics: Amino Acid Sequence; Amino Acid Substitution; Animals; Cysteine; Dimerization; Enzyme Activation; Enzyme Inhibitors; Glutamic Acid; Glutamine; Glycolates; Hydrogen-Ion Concentration; Leishmania mexicana; Methyl Methanesulfonate; Molecular Sequence Data; Mutagenesis, Site-Directed; Peptide Fragments; Proline; Protein Structure, Tertiary; Triose-Phosphate Isomerase; Trypanosoma brucei brucei; Trypanosoma cruzi | 2001 |
Flexibility of the Kir6.2 inward rectifier K(+) channel pore.
Topics: Amino Acid Sequence; Animals; Cadmium; COS Cells; Cysteine; Dimerization; Ethyl Methanesulfonate; Indicators and Reagents; Mesylates; Methyl Methanesulfonate; Models, Biological; Models, Molecular; Molecular Sequence Data; Pliability; Point Mutation; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Inwardly Rectifying; Protein Conformation; Quaternary Ammonium Compounds; Sequence Homology, Amino Acid | 2001 |
On the nature of conformational openings: native and unfolded-state hydrogen and thiol-disulfide exchange studies of ferric aquomyoglobin.
Topics: Amides; Animals; Circular Dichroism; Cysteine; Disulfides; Dithionitrobenzoic Acid; Guanidine; Hydrogen; Kinetics; Methyl Methanesulfonate; Models, Molecular; Mutation; Myoglobin; Protein Conformation; Protein Folding; Sulfhydryl Compounds; Thermodynamics; Whales | 2001 |
Structure of spin-labeled methylmethanethiolsulfonate in solution and bound to TEM-1 beta-lactamase determined by electron nuclear double resonance spectroscopy.
Topics: beta-Lactamases; Binding Sites; Cysteine; Electron Spin Resonance Spectroscopy; Methyl Methanesulfonate; Models, Molecular; Protein Conformation; Protein Structure, Secondary; Solvents; Spin Labels; Surface Properties | 2002 |
Thiol-disulphide interchange in tubulin: kinetics and the effect on polymerization.
Topics: 2,2'-Dipyridyl; Adenosine Triphosphate; Amino Acid Sequence; Biopolymers; Cysteine; Disulfides; Dithionitrobenzoic Acid; Guanosine Diphosphate; Guanosine Triphosphate; Kinetics; Methyl Methanesulfonate; Molecular Structure; Nitrobenzoates; Protein Denaturation; Sulfhydryl Compounds; Tubulin | 2005 |
Disulfiram irreversibly aggregates betaine aldehyde dehydrogenase--a potential target for antimicrobial agents against Pseudomonas aeruginosa.
Topics: Alanine; Anti-Infective Agents; Betaine-Aldehyde Dehydrogenase; Binding Sites; Catalysis; Chromatography; Cysteine; Disulfiram; Dithionitrobenzoic Acid; Enzyme Inhibitors; Glutathione; Kinetics; Methyl Methanesulfonate; Models, Chemical; Mutagenesis, Site-Directed; Mutation; NADP; Protein Conformation; Protein Structure, Quaternary; Proteins; Pseudomonas aeruginosa; Sulfhydryl Compounds; Temperature; Time Factors | 2006 |
Crosstalk between the subunits of the homodimeric enzyme triosephosphate isomerase.
Topics: Amino Acid Sequence; Animals; Cysteine; Dimerization; Kinetics; Methyl Methanesulfonate; Mutagenesis, Site-Directed; Protein Interaction Mapping; Protein Structure, Quaternary; Triose-Phosphate Isomerase; Trypanosoma brucei brucei; Trypanosoma cruzi | 2007 |
Identification of cysteines in rat organic cation transporters rOCT1 (C322, C451) and rOCT2 (C451) critical for transport activity and substrate affinity.
Topics: Animals; Biological Transport, Active; Catecholamine Plasma Membrane Transport Proteins; Cysteine; Electric Capacitance; Electrophysiology; Exocytosis; Methyl Methanesulfonate; Models, Molecular; Oocytes; Organic Cation Transport Proteins; Organic Cation Transporter 2; Protein Binding; Protein Conformation; Rats; Substrate Specificity; Xenopus laevis | 2007 |
Tissue factor coagulant function is enhanced by protein-disulfide isomerase independent of oxidoreductase activity.
Topics: Animals; Bacitracin; Binding Sites; Cattle; Cells, Cultured; Cysteine; Enzyme Activation; Ethylmaleimide; Factor VIIa; Factor X; Humans; Methyl Methanesulfonate; Molecular Chaperones; Multienzyme Complexes; Oxidation-Reduction; Phospholipids; Protein Disulfide-Isomerases; Protein Structure, Quaternary; Signal Transduction; Thromboplastin | 2007 |
Control of inward rectifier K channel activity by lipid tethering of cytoplasmic domains.
Topics: Bacterial Proteins; Burkholderia pseudomallei; Cell-Free System; Cloning, Molecular; Cysteine; Ethyl Methanesulfonate; Ion Channel Gating; Membrane Lipids; Mesylates; Methyl Methanesulfonate; Models, Molecular; Mutation; Potassium Channels, Inwardly Rectifying; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Rubidium Radioisotopes; Sulfhydryl Reagents | 2007 |
Species-specific inhibition of Giardia lamblia triosephosphate isomerase by localized perturbation of the homodimer.
Topics: Animals; Cysteine; Dimerization; Dithionitrobenzoic Acid; Enzyme Stability; Giardia lamblia; Hot Temperature; Methyl Methanesulfonate; Models, Molecular; Protein Structure, Secondary; Protozoan Proteins; Triose-Phosphate Isomerase | 2008 |
Human glyceraldehyde-3-phosphate dehydrogenase plays a direct role in reactivating oxidized forms of the DNA repair enzyme APE1.
Topics: Active Transport, Cell Nucleus; Antibiotics, Antineoplastic; Bleomycin; Cell Line, Tumor; Cell Nucleus; Cysteine; DNA Repair; DNA-(Apurinic or Apyrimidinic Site) Lyase; Enzyme Activation; Genome, Human; Glyceraldehyde-3-Phosphate Dehydrogenases; Humans; Methyl Methanesulfonate; Mutagens; Oxidation-Reduction; Oxidative Stress; RNA, Small Interfering; Ultraviolet Rays | 2008 |
Chelator-facilitated chemical modification of IMP-1 metallo-beta-lactamase and its consequences on metal binding.
Topics: beta-Lactamases; Chelating Agents; Cysteine; Dinitrobenzenes; Methods; Methyl Methanesulfonate; Phosphines; Protein Binding; Thiocyanates; Zinc | 2009 |
Identification of multiple folding pathways of monellin using pulsed thiol labeling and mass spectrometry.
Topics: Cysteine; Kinetics; Methyl Methanesulfonate; Models, Molecular; Plant Proteins; Protein Folding; Protein Refolding; Protein Structure, Secondary; Solvents; Spectrometry, Fluorescence; Spectrometry, Mass, Electrospray Ionization; Staining and Labeling; Sulfhydryl Compounds; Tryptophan | 2011 |
The TM2 6' position of GABA(A) receptors mediates alcohol inhibition.
Topics: Alcohols; Amino Acid Substitution; Animals; Binding Sites; Binding, Competitive; Cysteine; Cystine; DNA, Complementary; Drug Synergism; Electrophysiological Phenomena; Ethanol; Etomidate; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Humans; Methionine; Methyl Methanesulfonate; Molecular Dynamics Simulation; Oocytes; Patch-Clamp Techniques; Receptors, GABA-A; Tryptophan; Xenopus laevis | 2012 |
Propofol binding to the resting state of the gloeobacter violaceus ligand-gated ion channel (GLIC) induces structural changes in the inter- and intrasubunit transmembrane domain (TMD) cavities.
Topics: Allosteric Regulation; Amino Acid Substitution; Anesthetics, Intravenous; Animals; Bacterial Proteins; Cyanobacteria; Cysteine; Hydrogen-Ion Concentration; Ion Channel Gating; Kinetics; Ligand-Gated Ion Channels; Membrane Potentials; Methyl Methanesulfonate; Molecular Docking Simulation; Mutagenesis, Site-Directed; Propofol; Protein Binding; Protein Interaction Domains and Motifs; Protein Stability; Protein Structure, Secondary; Protein Subunits; Structural Homology, Protein; Xenopus laevis | 2013 |
Thiol-blocking electrophiles interfere with labeling and detection of protein sulfenic acids.
Topics: Ascorbic Acid; Cyclohexanones; Cysteine; Dithiothreitol; Ethylmaleimide; Iodoacetamide; Methyl Methanesulfonate; Oxidation-Reduction; Proteins; Reactive Oxygen Species; Spectrometry, Mass, Electrospray Ionization; Sulfenic Acids; Sulfhydryl Compounds | 2013 |
Quantification of a Novel DNA-Protein Cross-Link Product Formed by Reacting Apurinic/Apyrimidinic Sites in DNA with Cysteine Residues in Protein by Liquid Chromatography-Tandem Mass Spectrometry Coupled with the Stable Isotope-Dilution Method.
Topics: Amino Acid Sequence; Chromatography, Liquid; Cysteine; DNA; HeLa Cells; Humans; Isotopes; Kinetics; Methyl Methanesulfonate; Models, Molecular; Nucleic Acid Conformation; Protein Binding; Protein Conformation; Tandem Mass Spectrometry | 2019 |