methyl isocyanate has been researched along with hydrazine in 4 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (75.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Baumann, RP; Brent, TP; Penketh, PG; Remack, JS; Sartorelli, AC; Shyam, K | 1 |
| Baumann, RP; Penketh, PG; Sartorelli, AC; Seow, HA; Shyam, K | 1 |
| Pigneux, A | 1 |
| Cincotta, DJ; Ghazvinian, R; He, Y; Ji, W; Li, Y; Min, W; Praggastis, A; Rice, KP; Yang, M; Zhou, HJ | 1 |
1 review(s) available for methyl isocyanate and hydrazine
| Article | Year |
|---|---|
Laromustine, a sulfonyl hydrolyzing alkylating prodrug for cancer therapy.
Topics: Aged; Animals; Antineoplastic Agents, Alkylating; Clinical Trials as Topic; Humans; Hydrazines; Isocyanates; Middle Aged; Neoplasms; Prodrugs; Sulfonamides | 2009 |
3 other study(ies) available for methyl isocyanate and hydrazine
| Article | Year |
|---|---|
1,2-Bis(methylsulfonyl)-1-(2-chloroethyl)-2-[(methylamino)carbonyl]hydrazine (VNP40101M): II. Role of O6-alkylguanine-DNA alkyltransferase in cytotoxicity.
Topics: Animals; Antineoplastic Agents, Alkylating; Cell Survival; CHO Cells; Cricetinae; Cricetulus; Drug Resistance, Neoplasm; Drug Synergism; Humans; Hydrazines; Isocyanates; O(6)-Methylguanine-DNA Methyltransferase; Structure-Activity Relationship; Transfection | 2004 |
The antineoplastic efficacy of the prodrug Cloretazine is produced by the synergistic interaction of carbamoylating and alkylating products of its activation.
Topics: Animals; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Biotransformation; Cell Line; Cells, Cultured; CHO Cells; Cricetinae; Drug Synergism; Guanine; HL-60 Cells; Humans; Hydrazines; Isocyanates; O(6)-Methylguanine-DNA Methyltransferase; Prodrugs; Sulfonamides; Transfection | 2005 |
Carbamoylating activity associated with the activation of the antitumor agent laromustine inhibits angiogenesis by inducing ASK1-dependent endothelial cell death.
Topics: Animals; Antineoplastic Agents; Biocatalysis; Carbamates; Cattle; Cell Death; Cells, Cultured; Endothelial Cells; Humans; Hydrazines; Immunoblotting; Isocyanates; MAP Kinase Kinase Kinase 5; Mitogen-Activated Protein Kinase 8; Neovascularization, Physiologic; Signal Transduction; Sulfonamides; Thioredoxin Reductase 1; Thioredoxins | 2014 |