methyl-ethyl-ketone-peroxide and diethyl-maleate

methyl-ethyl-ketone-peroxide has been researched along with diethyl-maleate* in 1 studies

Other Studies

1 other study(ies) available for methyl-ethyl-ketone-peroxide and diethyl-maleate

ArticleYear
Skin-tumour promoting activity of methyl ethyl ketone peroxide--a potent lipid-peroxidizing agent.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 1984, Volume: 22, Issue:11

    The tumour-promoting activity of methyl ethyl ketone peroxide (MEKP) was tested on the skin of hairless mice using a two-stage initiation-promotion protocol. When ultraviolet radiation in the UVB region (280-320 nm) was used as tumour initiator, MEKP showed weak promoting activity. The promotional activity of MEKP was potentiated by diethyl maleate, which is known to deplete intracellular glutathione, suggesting that lipid peroxidation may be important in the tumour promotion.

    Topics: Acetone; Administration, Topical; Animals; Butanones; Carcinogens; Dibutyl Phthalate; Drug Synergism; Female; Lipid Peroxides; Male; Maleates; Mice; Mice, Hairless; Peroxides; Skin Neoplasms; Ultraviolet Rays

1984