methyl diethyldithiocarbamate has been researched along with ditiocarb in 26 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (34.62) | 18.7374 |
| 1990's | 16 (61.54) | 18.2507 |
| 2000's | 1 (3.85) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Angelo, HR; Christensen, JK; Johansson, B; Møller, IW; Rønsted, P | 1 |
| Kitson, TM | 1 |
| Faiman, MD; Yourick, JJ | 2 |
| Brazier, JL; Coquet, B; Desage, M; Rousseau-Tsangaris, M; Scappaticci, B; Soubeyrand, J | 1 |
| Johansson, B | 3 |
| Arnold, E; Johansson, B; Petersen, EN | 1 |
| Johansson, B; Stankiewicz, Z | 1 |
| Helander, A; Johansson, B | 1 |
| Petersen, EN | 1 |
| Bertram, B; Pool, BL; Tacchi, AM; Wiessler, M | 1 |
| Artman, L; Faiman, MD; Maziasz, T | 1 |
| Faiman, MD; Madan, A; Williams, TD | 1 |
| Faiman, MD; Madan, A | 1 |
| Faiman, MD; Hart, BW | 1 |
| Goh, L; Kitson, KE; Kitson, TM | 1 |
| Glauser, TA; Lipsky, JJ; Nelson, AN; Weinshilboum, RM; Zembower, DE | 1 |
| Fauq, AH; Lam-Holt, J; Lipsky, JJ; Mays, DC; Nelson, AN | 1 |
| Johnson, KL; Lipsky, JJ; Mays, DC; Naylor, S; Veverka, KA | 1 |
| Aquilina, JW; Berti, JJ; Lipsky, JJ; Mays, DC | 1 |
| Johnson, KL; Lam-Holt, J; Lipsky, JJ; Mays, DC; Naylor, S; Tomlinson, AJ | 1 |
| Faiman, MD; Madan, A; Parkinson, A | 1 |
| Akiyoshi, T; Arakaki, M; Kase, A | 1 |
| Lipsky, JJ; Macomber, DW; Mays, DC; Pike, MG | 1 |
26 other study(ies) available for methyl diethyldithiocarbamate and ditiocarb
| Article | Year |
|---|---|
Dose-effect relationship of disulfiram in human volunteers. II: A study of the relation between the disulfiram-alcohol reaction and plasma concentrations of acetaldehyde, diethyldithiocarbamic acid methyl ester, and erythrocyte aldehyde dehydrogenase acti
Topics: Acetaldehyde; Adult; Aldehyde Dehydrogenase; Catecholamines; Disulfiram; Ditiocarb; Dopamine beta-Hydroxylase; Dose-Response Relationship, Drug; Erythrocytes; Ethanol; Female; Hemodynamics; Humans; Male; Middle Aged | 1991 |
Effect of some thiocarbamate compounds on aldehyde dehydrogenase and implications for the disulfiram ethanol reaction.
Topics: Aldehyde Dehydrogenase; Animals; Carbamates; Disulfides; Disulfiram; Ditiocarb; Kinetics; Liver; Sheep; Thiocarbamates | 1991 |
Disulfiram metabolism as a requirement for the inhibition of rat liver mitochondrial low Km aldehyde dehydrogenase.
Topics: Aldehyde Dehydrogenase; Animals; Cytochrome P-450 Enzyme System; Disulfiram; Ditiocarb; Dose-Response Relationship, Drug; Female; Imidazoles; Kinetics; Mitochondria, Liver; Rats; Rats, Inbred Strains | 1991 |
Determination of sodium diethyldithiocarbamate (Imuthiol) and its S-methyl metabolite by gas chromatography-mass spectrometry. Use of deuteromethyl iodide derivatization.
Topics: Deuterium; Disulfiram; Ditiocarb; Gas Chromatography-Mass Spectrometry; Humans | 1990 |
Plasma protein binding of disulfiram and its metabolite diethylthiocarbamic acid methyl ester.
Topics: Aldehyde Dehydrogenase; Binding Sites; Blood Proteins; Disulfiram; Ditiocarb; Electrophoresis, Agar Gel; Humans; Serum Albumin | 1990 |
Comparative aspects of disulfiram and its metabolites in the disulfiram-ethanol reaction in the rat.
Topics: Acetaldehyde; Aldehyde Dehydrogenase; Animals; Blood Pressure; Disulfiram; Ditiocarb; Ethanol; Female; Rats; Rats, Inbred Strains | 1989 |
Diethylthiocarbamic acid methyl ester. A potent inhibitor of aldehyde dehydrogenase found in rats treated with disulfiram or diethyldithiocarbamic acid methyl ester.
Topics: Aldehyde Dehydrogenase; Animals; Blood Pressure; Cytochrome P-450 Enzyme System; Disulfiram; Ditiocarb; Ethanol; Heart Rate; Humans; Male; Microsomes, Liver; Mixed Function Oxygenases; Rats; Rats, Inbred Strains; Thiocarbamates | 1989 |
Inhibition of erythrocyte aldehyde dehydrogenase activity and elimination kinetics of diethyldithiocarbamic acid methyl ester and its monothio analogue after administration of single and repeated doses of disulfiram to man.
Topics: Adult; Alcoholism; Aldehyde Dehydrogenase; Disulfiram; Ditiocarb; Erythrocytes; Ethanol; Female; Humans; Male; Middle Aged; Oxidation-Reduction | 1989 |
Inhibition of human erythrocyte and leukocyte aldehyde dehydrogenase activities by diethylthiocarbamic acid methyl ester. An in vivo metabolite of disulfiram.
Topics: Aldehyde Dehydrogenase; Disulfiram; Ditiocarb; Erythrocytes; Humans; In Vitro Techniques; Kinetics; Leukocytes; Structure-Activity Relationship; Thiocarbamates | 1989 |
Diethylthiocarbamic acid methyl ester: a suicide inhibitor of liver aldehyde dehydrogenases?
Topics: Aldehyde Dehydrogenase; Animals; Cattle; Ditiocarb; Glutathione; In Vitro Techniques; Kinetics; Liver; Mercaptoethanol; Thiocarbamates | 1989 |
Pharmacological effects of diethylthiocarbamic acid methyl ester, the active metabolite of disulfiram?
Topics: Animals; Blood Pressure; Body Temperature; Disulfiram; Ditiocarb; Dose-Response Relationship, Drug; Ethanol; Hemodynamics; Injections, Intraperitoneal; Male; Mice; Rats; Rats, Inbred Strains; Thiocarbamates | 1989 |
Rapid and sensitive on-line precolumn purification and high-performance liquid chromatographic assay for disulfiram and its metabolites.
Topics: Alcoholism; Biotransformation; Chemical Phenomena; Chemistry; Chromatography, High Pressure Liquid; Disulfiram; Ditiocarb; Humans; Male; Protein Binding; Thiocarbamates | 1986 |
In vitro formation of methyldiethyldithiocarbamate after the reaction of nitrosoacetoxymethylmethylamine or methylnitrosourea with disulfiram.
Topics: Animals; Biotransformation; Chemical Phenomena; Chemistry; Cytosol; Dimethylnitrosamine; Disulfiram; Ditiocarb; Drug Interactions; Liver; Male; Methylnitrosourea; Microsomes, Liver; Nitrosourea Compounds; Rats; Rats, Inbred Strains; Thiocarbamates | 1982 |
Diethyldithiocarbamic acid-methyl ester distribution, elimination, and LD50 in the rat after intraperitoneal administration.
Topics: Animals; Ditiocarb; Injections, Intraperitoneal; Lethal Dose 50; Male; Metabolic Clearance Rate; Mice; Mice, Inbred ICR; Rats; Rats, Inbred Strains; Thiocarbamates; Tissue Distribution | 1983 |
Glutathione- and glutathione-S-transferase-dependent oxidative desulfuration of the thione xenobiotic diethyldithiocarbamate methyl ester.
Topics: Aldehyde Dehydrogenase; Animals; Ditiocarb; Glutathione; Glutathione Transferase; Male; Microsomes, Liver; Oxidation-Reduction; Rats; Rats, Sprague-Dawley; Sulfur | 1994 |
Characterization of diethyldithiocarbamate methyl ester sulfine as an intermediate in the bioactivation of disulfiram.
Topics: Aldehyde Dehydrogenase; Animals; Biotransformation; Cytochrome P-450 Enzyme Inhibitors; Disulfiram; Ditiocarb; Ethanol; Male; Rats; Rats, Sprague-Dawley; Sulfoxides | 1995 |
In vivo pharmacodynamic studies of the disulfiram metabolite S-methyl N,N-diethylthiolcarbamate sulfoxide: inhibition of liver aldehyde dehydrogenase.
Topics: Acetaldehyde; Aldehyde Dehydrogenase; Animals; Cattle; Culture Techniques; Disulfiram; Ditiocarb; Dose-Response Relationship, Drug; Liver; Male; Mitochondria, Liver; Rats; Rats, Sprague-Dawley | 1994 |
Effect of some compounds related to disulfiram on mitochondrial aldehyde dehydrogenase in vitro and in vivo.
Topics: Aldehyde Dehydrogenase; Animals; Carbamates; Disulfides; Disulfiram; Ditiocarb; Female; In Vitro Techniques; Mitochondria, Liver; Rats; Rats, Sprague-Dawley; Sheep | 1993 |
Diethyldithiocarbamate S-methylation: evidence for catalysis by human liver thiol methyltransferase and thiopurine methyltransferase.
Topics: Aldehyde Dehydrogenase; Catalysis; Cations; Chromatography, Ion Exchange; Cytosol; Ditiocarb; Enzyme Stability; Hot Temperature; Humans; Hydrogen-Ion Concentration; Kinetics; Liver; Methylation; Methyltransferases; Microsomes, Liver; Proteins; S-Adenosylmethionine; Time Factors | 1993 |
S-methyl-N,N-diethylthiocarbamate sulfoxide and S-methyl-N,N-diethylthiocarbamate sulfone, two candidates for the active metabolite of disulfiram.
Topics: Alcohol Deterrents; Aldehyde Dehydrogenase; Animals; Biotransformation; Disulfiram; Ditiocarb; Dose-Response Relationship, Drug; Enzyme Inhibitors; Glutathione; Liver; Male; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship | 1996 |
Inhibition of aldehyde dehydrogenase by disulfiram and its metabolite methyl diethylthiocarbamoyl-sulfoxide.
Topics: Aldehyde Dehydrogenase; Disulfiram; Dithiothreitol; Ditiocarb; Enzyme Inhibitors; Sulfoxides | 1997 |
Effect of a disulfiram metabolite on retinaldehyde metabolism.
Topics: Aldehyde Dehydrogenase; Disulfiram; Ditiocarb; Enzyme Inhibitors; Humans; Male; Retinaldehyde | 1997 |
Inhibition of human mitochondrial aldehyde dehydrogenase by the disulfiram metabolite S-methyl-N,N-diethylthiocarbamoyl sulfoxide: structural characterization of the enzyme adduct by HPLC-tandem mass spectrometry.
Topics: Aldehyde Dehydrogenase; Amino Acid Sequence; Disulfiram; Ditiocarb; Enzyme Inhibitors; Humans; Mass Spectrometry; Mitochondria; Molecular Sequence Data; Sulfoxides | 1997 |
Identification of the human P-450 enzymes responsible for the sulfoxidation and thiono-oxidation of diethyldithiocarbamate methyl ester: role of P-450 enzymes in disulfiram bioactivation.
Topics: Alcohol Deterrents; Aldehyde Dehydrogenase; Biotransformation; Culture Techniques; Cytochrome P-450 Enzyme System; Disulfiram; Ditiocarb; Enzyme Inhibitors; Humans; Microsomes, Liver; Oxidation-Reduction | 1998 |
[Studies on the biological effects of disulufiram--effect of an active metabolite of disulfiram on the activity of delta-aminolevulinic acid synthetase].
Topics: 5-Aminolevulinate Synthetase; Animals; Dactinomycin; Ditiocarb; Dose-Response Relationship, Drug; Drug Combinations; Drugs, Chinese Herbal; Enzyme Inhibitors; Glycyrrhiza; Ketones; Liver; Male; Nucleic Acid Synthesis Inhibitors; Paeonia; Phenobarbital; Rats; Rats, Wistar | 1998 |
Metabolism of a disulfiram metabolite, S-methyl N,N-diethyldithiocarbamate, by flavin monooxygenase in human renal microsomes.
Topics: Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Ditiocarb; Enzyme Inhibitors; Humans; Imidazoles; Isoenzymes; Kidney; Kinetics; Microsomes; NADP; Oxygenases; Spectrophotometry, Ultraviolet | 2001 |