methyl 2-((3,4-dihydro-3,4-dioxo-1-naphthalenyl)amino)benzoate has been researched along with naphthoquinones in 15 studies
| Studies (methyl 2-((3,4-dihydro-3,4-dioxo-1-naphthalenyl)amino)benzoate) | Trials (methyl 2-((3,4-dihydro-3,4-dioxo-1-naphthalenyl)amino)benzoate) | Recent Studies (post-2010) (methyl 2-((3,4-dihydro-3,4-dioxo-1-naphthalenyl)amino)benzoate) | Studies (naphthoquinones) | Trials (naphthoquinones) | Recent Studies (post-2010) (naphthoquinones) |
|---|---|---|---|---|---|
| 16 | 0 | 0 | 7,110 | 149 | 2,923 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (40.00) | 18.7374 |
| 1990's | 8 (53.33) | 18.2507 |
| 2000's | 1 (6.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Grim, KS; Kimble, EF; Kowalski, TJ; Macchia, WM; Roland, DM; White, DH | 1 |
| Brubaker, WF; Douglas, FL; Kotake, AN; Kuwahara, SK; Tripp, S; Williams, E | 1 |
| Douglas, FL; Jones, DR; Kotake, AN; Kuwahara, SK; Oglesby, TD; Rakhit, A; Soliman, VF; Tripp, SL; Wasley, JW | 1 |
| Piper, PJ; Yaacob, HB | 2 |
| Colombo, C; Dotson, R; Ghai, G; Kimble, EF; Ku, EC; Lee, WH; Oglesby, TD; Raychaudhuri, A; Wasley, JW; White, D | 1 |
| Colombo, C; Dotson, R; Ghai, G; Kimble, EF; Ku, EC; Lee, WH; Oglesby, TD; Raychaudhuri, A; Wasley, JW | 1 |
| Cooper, DR; Kelliher, GJ; Kowey, PR | 1 |
| Cook, JA; Halushka, PV; Hennigar, RA; Matera, G; Oglesby, TD; Tempel, GE; Wise, WC | 1 |
| Holladay, CS; Spangelo, BL; Wright, RM | 1 |
| Kruse-Elliott, KT; Olson, NC | 1 |
| Johnson, LW; Kruse-Elliott, KT; Olson, NC | 1 |
| Cathcart, MK; Folcik, VA | 1 |
| Abacioğlu, N; Cakici, I; Kanzik, I; Tunçtan, B | 1 |
| Beckmann, N; Blé, FX; Cannet, C; Fozard, JR; Karmouty-Quintana, H; Page, CP; Zurbruegg, S | 1 |
15 other study(ies) available for methyl 2-((3,4-dihydro-3,4-dioxo-1-naphthalenyl)amino)benzoate and naphthoquinones
| Article | Year |
|---|---|
Leukotriene biosynthesis inhibition by aryl and aroyl substituted naphthoquinones.
Topics: Animals; Biological Availability; Calcimycin; Dogs; Female; Guinea Pigs; Half-Life; In Vitro Techniques; Leukotriene B4; Lipoxygenase Inhibitors; Male; N-Formylmethionine Leucyl-Phenylalanine; Naphthoquinones; ortho-Aminobenzoates; Radioimmunoassay | 1991 |
Determination of the 5-lipoxygenase inhibitor (CGS 8515) in plasma by high-performance liquid chromatography using reductive electrochemical detection.
Topics: Animals; Chromatography, High Pressure Liquid; Dogs; Electrochemistry; Lipoxygenase Inhibitors; Naphthoquinones; ortho-Aminobenzoates | 1990 |
Pharmacokinetic screening of o-naphthoquinone 5-lipoxygenase inhibitors.
Topics: Administration, Oral; Animals; Dogs; Dose-Response Relationship, Drug; Enzyme Inhibitors; Humans; Lipoxygenase Inhibitors; Liver; Naphthoquinones; ortho-Aminobenzoates; Portacaval Shunt, Surgical; Solubility | 1990 |
Interactions of platelet activating factor, thromboxane A2 and leukotrienes in guinea-pig heart.
Topics: Anaphylaxis; Animals; Azepines; Cyclooxygenase Inhibitors; Guinea Pigs; Heart; In Vitro Techniques; Indomethacin; Leukotrienes; Lipoxygenase Inhibitors; Naphthoquinones; ortho-Aminobenzoates; Platelet Activating Factor; Thromboxane A2; Triazines; Triazoles | 1989 |
Characterization of CGS 8515 as a selective 5-lipoxygenase (5-LO) inhibitor.
Topics: Animals; Arachidonate 5-Lipoxygenase; Arachidonate Lipoxygenases; Arachidonic Acids; Calcimycin; Cell Movement; Humans; Kinetics; Leukocytes; Lipoxygenase Inhibitors; Naphthoquinones; ortho-Aminobenzoates; Rats | 1989 |
Characterization of CGS 8515 as a selective 5-lipoxygenase inhibitor using in vitro and in vivo models.
Topics: Animals; Arachidonate Lipoxygenases; Arachidonic Acid; Arachidonic Acids; Benzoquinones; Biotransformation; Blood Platelets; Calcimycin; Dexamethasone; Guinea Pigs; Humans; Hydroxyeicosatetraenoic Acids; Indomethacin; Leukocytes; Leukotriene B4; Lipoxygenase Inhibitors; Male; Naphthoquinones; ortho-Aminobenzoates; Pleurisy; Quinones; Rats; Rats, Inbred Strains; Sheep | 1988 |
Modulation of arachidonic acid metabolites and vulnerability to ventricular fibrillation during myocardial ischemia in the cat.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Arachidonic Acids; Cardiac Pacing, Artificial; Cats; Chromones; Coronary Disease; Female; Male; Naphthoquinones; ortho-Aminobenzoates; Pyrazoles; SRS-A; Sulfinpyrazone; Ventricular Fibrillation | 1988 |
Inhibition of leukotriene release in anaphylactic guinea-pig hearts by a 5-lipoxygenase inhibitor, CGS 8515.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Anaphylaxis; Animals; Guinea Pigs; Heart; In Vitro Techniques; Lipoxygenase Inhibitors; Male; Naphthoquinones; ortho-Aminobenzoates; Ovalbumin; Perfusion; Prostaglandin-Endoperoxide Synthases; Pyrazoles; SRS-A | 1988 |
Beneficial effects of a 5-lipoxygenase inhibitor in endotoxic shock in the rat.
Topics: Animals; Arachidonate Lipoxygenases; Blood Pressure; Hematocrit; Leukopenia; Lipoxygenase Inhibitors; Male; Naphthoquinones; ortho-Aminobenzoates; Rats; Shock, Septic; Thrombocytopenia; Thromboxane B2 | 1988 |
Lipopolysaccharide induces interleukin-6 release from rat peritoneal macrophages in vitro: evidence for a novel mechanism.
Topics: Animals; Antigens, CD; Antigens, Differentiation, Myelomonocytic; In Vitro Techniques; Indomethacin; Interleukin-1; Interleukin-6; Lipopolysaccharide Receptors; Lipopolysaccharides; Macrophages, Peritoneal; Male; Naphthoquinones; ortho-Aminobenzoates; Pertussis Toxin; Rats; Signal Transduction; Thromboxane B2; Virulence Factors, Bordetella | 1993 |
CGS 8515 and indomethacin attenuate cytokine-induced cardiopulmonary dysfunction in pigs.
Topics: 6-Ketoprostaglandin F1 alpha; Albumins; Animals; Arachidonic Acids; Bronchoalveolar Lavage Fluid; Chromatography, High Pressure Liquid; Cyclooxygenase Inhibitors; Cytokines; Dinoprost; Drug Synergism; Eicosanoids; Heart; Heart Diseases; Hydroxyeicosatetraenoic Acids; Indomethacin; Injections, Intravenous; Interleukin-1; Leukotriene B4; Lipoxygenase Inhibitors; Lung; Lung Diseases; Naphthoquinones; ortho-Aminobenzoates; Swine; Thromboxane B2; Tumor Necrosis Factor-alpha; Vascular Resistance | 1993 |
Effect of 5-lipoxygenase and cyclooxygenase blockade on porcine hemodynamics during continuous infusion of platelet-activating factor.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Azepines; Blood; Calcimycin; Chromatography, High Pressure Liquid; Cyclooxygenase Inhibitors; Hemodynamics; Hypertension, Pulmonary; In Vitro Techniques; Indomethacin; Infusions, Intra-Arterial; Leukotriene B4; Lipoxygenase Inhibitors; Naphthoquinones; ortho-Aminobenzoates; Platelet Activating Factor; Swine; Thromboxane B2; Triazoles | 1993 |
Assessment of 5-lipoxygenase involvement in human monocyte-mediated LDL oxidation.
Topics: Acetamides; Arachidonate 15-Lipoxygenase; Arachidonate 5-Lipoxygenase; Benzyl Compounds; Humans; Hydroxamic Acids; In Vitro Techniques; Lipoproteins, LDL; Lipoxygenase Inhibitors; Monocytes; Naphthoquinones; ortho-Aminobenzoates; Oxidation-Reduction; Phenyl Ethers | 1993 |
Bradykinin-induced responses in a coaxial bioassay system composed of rat anococcygeus muscle and guinea pig trachea.
Topics: Anal Canal; Animals; Biological Assay; Bradykinin; Capsaicin; Dose-Response Relationship, Drug; Epithelium; Guinea Pigs; Lipoxygenase Inhibitors; Male; Muscle Contraction; Muscle Relaxation; Naphthoquinones; ortho-Aminobenzoates; Rats; Trachea | 1998 |
In vivo pharmacological evaluation of compound 48/80-induced airways oedema by MRI.
Topics: Androstadienes; Animals; Anti-Inflammatory Agents; Aza Compounds; Benzamides; Bronchoalveolar Lavage Fluid; Budesonide; Capsaicin; Cell Degranulation; Cromolyn Sodium; Disease Models, Animal; Drug Evaluation, Preclinical; Indomethacin; Lung; Magnetic Resonance Imaging; Male; Mast Cells; Naphthoquinones; ortho-Aminobenzoates; p-Methoxy-N-methylphenethylamine; Proteins; Pulmonary Edema; Rats; Rats, Inbred BN; Respiratory System Agents; Time Factors; Wortmannin | 2008 |