methyl 2-((3,4-dihydro-3,4-dioxo-1-naphthalenyl)amino)benzoate has been researched along with leukotriene b4 in 4 studies
Studies (methyl 2-((3,4-dihydro-3,4-dioxo-1-naphthalenyl)amino)benzoate) | Trials (methyl 2-((3,4-dihydro-3,4-dioxo-1-naphthalenyl)amino)benzoate) | Recent Studies (post-2010) (methyl 2-((3,4-dihydro-3,4-dioxo-1-naphthalenyl)amino)benzoate) | Studies (leukotriene b4) | Trials (leukotriene b4) | Recent Studies (post-2010) (leukotriene b4) |
---|---|---|---|---|---|
16 | 0 | 0 | 5,886 | 232 | 717 |
Protein | Taxonomy | methyl 2-((3,4-dihydro-3,4-dioxo-1-naphthalenyl)amino)benzoate (IC50) | leukotriene b4 (IC50) |
---|---|---|---|
Leukotriene B4 receptor 1 | Homo sapiens (human) | 0.0019 |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 1 (25.00) | 18.7374 |
1990's | 3 (75.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Grim, KS; Kimble, EF; Kowalski, TJ; Macchia, WM; Roland, DM; White, DH | 1 |
Colombo, C; Dotson, R; Ghai, G; Kimble, EF; Ku, EC; Lee, WH; Oglesby, TD; Raychaudhuri, A; Wasley, JW | 1 |
Kruse-Elliott, KT; Olson, NC | 1 |
Johnson, LW; Kruse-Elliott, KT; Olson, NC | 1 |
4 other study(ies) available for methyl 2-((3,4-dihydro-3,4-dioxo-1-naphthalenyl)amino)benzoate and leukotriene b4
Article | Year |
---|---|
Leukotriene biosynthesis inhibition by aryl and aroyl substituted naphthoquinones.
Topics: Animals; Biological Availability; Calcimycin; Dogs; Female; Guinea Pigs; Half-Life; In Vitro Techniques; Leukotriene B4; Lipoxygenase Inhibitors; Male; N-Formylmethionine Leucyl-Phenylalanine; Naphthoquinones; ortho-Aminobenzoates; Radioimmunoassay | 1991 |
Characterization of CGS 8515 as a selective 5-lipoxygenase inhibitor using in vitro and in vivo models.
Topics: Animals; Arachidonate Lipoxygenases; Arachidonic Acid; Arachidonic Acids; Benzoquinones; Biotransformation; Blood Platelets; Calcimycin; Dexamethasone; Guinea Pigs; Humans; Hydroxyeicosatetraenoic Acids; Indomethacin; Leukocytes; Leukotriene B4; Lipoxygenase Inhibitors; Male; Naphthoquinones; ortho-Aminobenzoates; Pleurisy; Quinones; Rats; Rats, Inbred Strains; Sheep | 1988 |
CGS 8515 and indomethacin attenuate cytokine-induced cardiopulmonary dysfunction in pigs.
Topics: 6-Ketoprostaglandin F1 alpha; Albumins; Animals; Arachidonic Acids; Bronchoalveolar Lavage Fluid; Chromatography, High Pressure Liquid; Cyclooxygenase Inhibitors; Cytokines; Dinoprost; Drug Synergism; Eicosanoids; Heart; Heart Diseases; Hydroxyeicosatetraenoic Acids; Indomethacin; Injections, Intravenous; Interleukin-1; Leukotriene B4; Lipoxygenase Inhibitors; Lung; Lung Diseases; Naphthoquinones; ortho-Aminobenzoates; Swine; Thromboxane B2; Tumor Necrosis Factor-alpha; Vascular Resistance | 1993 |
Effect of 5-lipoxygenase and cyclooxygenase blockade on porcine hemodynamics during continuous infusion of platelet-activating factor.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Azepines; Blood; Calcimycin; Chromatography, High Pressure Liquid; Cyclooxygenase Inhibitors; Hemodynamics; Hypertension, Pulmonary; In Vitro Techniques; Indomethacin; Infusions, Intra-Arterial; Leukotriene B4; Lipoxygenase Inhibitors; Naphthoquinones; ortho-Aminobenzoates; Platelet Activating Factor; Swine; Thromboxane B2; Triazoles | 1993 |