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methyl 2-((3,4-dihydro-3,4-dioxo-1-naphthalenyl)amino)benzoate and leukotriene b4

methyl 2-((3,4-dihydro-3,4-dioxo-1-naphthalenyl)amino)benzoate has been researched along with leukotriene b4 in 4 studies

Compound Research Comparison

Studies
(methyl 2-((3,4-dihydro-3,4-dioxo-1-naphthalenyl)amino)benzoate)
Trials
(methyl 2-((3,4-dihydro-3,4-dioxo-1-naphthalenyl)amino)benzoate)
Recent Studies (post-2010)
(methyl 2-((3,4-dihydro-3,4-dioxo-1-naphthalenyl)amino)benzoate)
Studies
(leukotriene b4)
Trials
(leukotriene b4)
Recent Studies (post-2010) (leukotriene b4)
16005,886232717

Protein Interaction Comparison

ProteinTaxonomymethyl 2-((3,4-dihydro-3,4-dioxo-1-naphthalenyl)amino)benzoate (IC50)leukotriene b4 (IC50)
Leukotriene B4 receptor 1Homo sapiens (human)0.0019

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19901 (25.00)18.7374
1990's3 (75.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Grim, KS; Kimble, EF; Kowalski, TJ; Macchia, WM; Roland, DM; White, DH1
Colombo, C; Dotson, R; Ghai, G; Kimble, EF; Ku, EC; Lee, WH; Oglesby, TD; Raychaudhuri, A; Wasley, JW1
Kruse-Elliott, KT; Olson, NC1
Johnson, LW; Kruse-Elliott, KT; Olson, NC1

Other Studies

4 other study(ies) available for methyl 2-((3,4-dihydro-3,4-dioxo-1-naphthalenyl)amino)benzoate and leukotriene b4

ArticleYear
Leukotriene biosynthesis inhibition by aryl and aroyl substituted naphthoquinones.
    Agents and actions, 1991, Volume: 34, Issue:1-2

    Topics: Animals; Biological Availability; Calcimycin; Dogs; Female; Guinea Pigs; Half-Life; In Vitro Techniques; Leukotriene B4; Lipoxygenase Inhibitors; Male; N-Formylmethionine Leucyl-Phenylalanine; Naphthoquinones; ortho-Aminobenzoates; Radioimmunoassay

1991
Characterization of CGS 8515 as a selective 5-lipoxygenase inhibitor using in vitro and in vivo models.
    Biochimica et biophysica acta, 1988, Apr-15, Volume: 959, Issue:3

    Topics: Animals; Arachidonate Lipoxygenases; Arachidonic Acid; Arachidonic Acids; Benzoquinones; Biotransformation; Blood Platelets; Calcimycin; Dexamethasone; Guinea Pigs; Humans; Hydroxyeicosatetraenoic Acids; Indomethacin; Leukocytes; Leukotriene B4; Lipoxygenase Inhibitors; Male; Naphthoquinones; ortho-Aminobenzoates; Pleurisy; Quinones; Rats; Rats, Inbred Strains; Sheep

1988
CGS 8515 and indomethacin attenuate cytokine-induced cardiopulmonary dysfunction in pigs.
    The American journal of physiology, 1993, Volume: 264, Issue:4 Pt 2

    Topics: 6-Ketoprostaglandin F1 alpha; Albumins; Animals; Arachidonic Acids; Bronchoalveolar Lavage Fluid; Chromatography, High Pressure Liquid; Cyclooxygenase Inhibitors; Cytokines; Dinoprost; Drug Synergism; Eicosanoids; Heart; Heart Diseases; Hydroxyeicosatetraenoic Acids; Indomethacin; Injections, Intravenous; Interleukin-1; Leukotriene B4; Lipoxygenase Inhibitors; Lung; Lung Diseases; Naphthoquinones; ortho-Aminobenzoates; Swine; Thromboxane B2; Tumor Necrosis Factor-alpha; Vascular Resistance

1993
Effect of 5-lipoxygenase and cyclooxygenase blockade on porcine hemodynamics during continuous infusion of platelet-activating factor.
    Prostaglandins, leukotrienes, and essential fatty acids, 1993, Volume: 49, Issue:2

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Azepines; Blood; Calcimycin; Chromatography, High Pressure Liquid; Cyclooxygenase Inhibitors; Hemodynamics; Hypertension, Pulmonary; In Vitro Techniques; Indomethacin; Infusions, Intra-Arterial; Leukotriene B4; Lipoxygenase Inhibitors; Naphthoquinones; ortho-Aminobenzoates; Platelet Activating Factor; Swine; Thromboxane B2; Triazoles

1993