methyl(acetoxymethyl)nitrosamine has been researched along with dimethylnitrosamine in 78 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 58 (74.36) | 18.7374 |
| 1990's | 15 (19.23) | 18.2507 |
| 2000's | 4 (5.13) | 29.6817 |
| 2010's | 1 (1.28) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Jurs, PC; Rose, SL | 1 |
| Berman, JJ; Rice, JM; Roller, PP; Wenk, ML | 2 |
| Doerjer, G; Hodgson, RM; Keefer, LK; Kleihues, P; Rice, JM; Roller, PP | 1 |
| Habs, M; Schmähl, D; Wagner, I | 1 |
| Joshi, SR; Keefer, LK; Rice, JM; Roller, PP; Wenk, ML | 1 |
| Kaufman, DG; Kaufmann, WK; Zhang, Y | 1 |
| Higinbotham, KG; Perantoni, AO; Rice, JM | 1 |
| Azuine, MA; Bhide, SV | 2 |
| Funae, Y; Guengerich, FP; Imaoka, S; Inui, Y; Oda, Y; Shimada, T; Yamazaki, H | 1 |
| Berger, MR; Garzon, F; Petru, E; Salas, M; Schmähl, D; Schwulera, U | 1 |
| Devor, D; Kaufman, DG; Kaufmann, WK; MacKenzie, SA; Qaqish, BF; Rice, JM; Smith, GJ; Wenk, ML | 1 |
| Hecht, SS; Peterson, LA | 1 |
| Berger, MR; Einecke, H; Garzon, FT; Koch, A; Maiwald, M; Peters, TJ; Rideout, JM; Seitz, HK; Simanowski, UA | 1 |
| Archer, MC; Catz-Biro, L; Hirani-Hojatti, S; Milligan, JR | 1 |
| Enomoto, T; Perantoni, AO; Reed, CD; Rice, JM; Watatani, M; Wenk, ML | 1 |
| Glickman, BW; Horsfall, MJ | 1 |
| Archer, MC; Brown, K; Hirani-Hojatti, S; Kovnat, A; Milligan, JR | 1 |
| Dolan, M; Fausto, N; Goyette, M; Kaufman, D; Kaufmann, W; Shank, PR | 1 |
| Brendler, S; Klein, RG; Monarca, S; Pasquini, R; Pool, BL; Schmezer, P; Zeller, WJ | 1 |
| Diwan, BA; Ohshima, M; Rice, JM | 1 |
| Berger, MR; Garzon, FT; Keppler, BK; Schmähl, D | 2 |
| Kaufman, DG; Kaufmann, WK; MacKenzie, SA; Rahija, RJ | 1 |
| Frank, N; Wiessler, M | 1 |
| Kaufman, DG; Kaufmann, WK; Ririe, DG | 1 |
| Berger, MR; Garzon, FT; Kommerell, B; Schmähl, D; Seitz, HK; Simanowski, UA | 1 |
| Berger, MR; Garzon, FT; Kirchner, H; Salas, M | 1 |
| Berger, MR; Bischoff, H; Keppler, BK; Schmähl, D | 1 |
| Archer, MC; Hirani-Hojatti, S; Milligan, JR | 1 |
| Kaufmann, WK; Novicki, DL; Tsao, MS | 1 |
| Anisimov, VN; Likhachev, AIa; Ovsiannikov, AI | 2 |
| Klein, RG; Komitowski, D; Schmezer, P | 1 |
| Amberger, H | 1 |
| Caesar, R; Frank, N; Scherf, HR; Wiessler, M | 1 |
| Appel, KE; Hildebrandt, AG; Rühl, CS; Schoepke, M; Wiessler, M | 1 |
| Berger, MR; Bischoff, H; Garzon, FT; Schmähl, D | 1 |
| Devor, D; Kaufman, DG; Kaufmann, WK; Rice, JM; Wenk, ML | 1 |
| Likhachev, AJ | 2 |
| Berger, MR; Bischoff, H; Fritschi, E; Henne, T; Herrmann, M; Pool, BL; Satzinger, G; Schmähl, D; Weiershausen, U | 1 |
| Blankenburg, G; Bochert, G; Neubert, D; Platzek, T; Wiessler, M | 1 |
| Kaufman, DG; Kaufmann, WK; MacKenzie, SA | 1 |
| Agrawal, RC; Bhide, SV; Lalitha, VS; Sarode, AV | 1 |
| Bertram, B; Pool, BL; Tacchi, AM; Wiessler, M | 1 |
| Biwer, E; Habs, M; Lorenz, M; Schmähl, D | 1 |
| Hermanek, PJ; Narisawa, T | 1 |
| Giedl, J; Hermanek, PJ | 1 |
| Habs, M; Hermanek, P; Narisawa, T; Schmähl, D | 1 |
| Gold, B; Hines, L | 1 |
| Caesar, R; Frank, N; Wiessler, M | 1 |
| Bicker, U; Edler, L; Heim, ME; Pahlke, W; Swoboda, M | 1 |
| Bhide, SV; Munir, KM; Sarode, AV; Soman, CS; Wiessler, M | 1 |
| Klein, RG | 1 |
| Amberger, H; Bachmann, U; Habs, M; Schmähl, D; Wagner, I | 1 |
| Habs, H; Habs, M; Schmähl, D | 1 |
| Bochert, G; Platzek, T; Rahm, U | 1 |
| Anisimov, VN; Keefer, LK; Likhachev, AJ; Ohshima, H; Ovsyannikov, AI; Reist, EJ | 1 |
| Berman, JJ; Reddick, R; Rice, JM | 1 |
| Amberger, H; Bachmann, U; Habs, M; Merz, R; Schmähl, D; Wagner, I | 1 |
| Eid, P; Goeldner, MP; Hirth, CG; Jost, P | 1 |
| Doertenbach, J; Hettler, J; Ivankovic, S; Junghanns, K; Siebert, A; von Gerstenbergk, L; Wiessler, M | 1 |
| Appel, KE; Frank, N; Wiessler, M | 1 |
| Frank, N; Janzowski, C; Wiessler, M | 1 |
| Habs, M; Kretzer, H; Schmähl, D | 1 |
| Gradia, S; Hecht, SS; Peterson, LA; Ronai, ZA | 1 |
| Buzard, GS; Dragnev, KH; Rice, JM; Thorne, KL; Vandeborne, GF; Vincent, KA; Weghorst, CM | 1 |
| Bhide, SV; Chakradeo, PP; Kayal, JJ | 1 |
| Guttenplan, JB | 1 |
| Berger, MR; Seelig, MH | 1 |
| Castonguay, A; Cloutier, JF; Drouin, R | 1 |
| Crankshaw, DL; Donaldson, EE; Kenney, PJ; Peterson, LA; Thomson, NM | 1 |
| Peterson, LA; Thomson, NM; Wattenberg, EV; Wichmann, AE | 1 |
| Jones, R; Shallop, A; Tretyakova, N; Upadhyaya, P; Ziegel, R | 1 |
| Augusto, LA; Bissonnette, EY; Castonguay, A; Gaudreault, M; Proulx, LI; Turmel, V | 1 |
| Brown, LC; Cummings, ME; Li, L; Patel, Y; Pegg, AE; Peterson, LA; Stram, DO; Urban, AM; Vu, CC; Warmka, JK; Wattenberg, EV | 1 |
1 review(s) available for methyl(acetoxymethyl)nitrosamine and dimethylnitrosamine
| Article | Year |
|---|---|
DNA repair induced by alkylating carcinogens.
Topics: 1,2-Dimethylhydrazine; Aging; Alkylating Agents; Animals; Carcinogens; Cricetinae; Dimethylhydrazines; Dimethylnitrosamine; DNA Repair; Ethylnitrosourea; Mesocricetus; Methylation; Methylnitrosourea; Rats | 1983 |
77 other study(ies) available for methyl(acetoxymethyl)nitrosamine and dimethylnitrosamine
| Article | Year |
|---|---|
Computer-assisted studies of structure-activity relationships of N-nitroso compounds using pattern recognition.
Topics: Carcinogens; Computers; Nitrosamines; Nitroso Compounds; Pattern Recognition, Automated; Structure-Activity Relationship | 1982 |
Dependence of tumor spectrum on route of administration in Sprague-Dawley rats as a result of single or multiple injections of methyl(acetoxymethyl)nitrosamine.
Topics: Administration, Oral; Animals; Dimethylnitrosamine; Female; Gastrointestinal Neoplasms; Injections; Male; Neoplasms, Experimental; Nitrosamines; Organ Specificity; Rats; Rats, Inbred Strains; Sex Factors | 1979 |
Intestinal tumors induced by a single intraperitoneal injection of methyl(acetoxymethyl)nitrosamine in three strains of rats.
Topics: Animals; Dimethylnitrosamine; Female; Intestinal Neoplasms; Male; Neoplasms, Experimental; Nitrosamines; Rats; Rats, Inbred BUF; Rats, Inbred F344; Sex Factors; Species Specificity; Splenic Neoplasms; Testicular Neoplasms | 1979 |
Correlation of DNA methylation by methyl(acetoxymethyl)nitrosamine with organ-specific carcinogenicity in rats.
Topics: Animals; Biotransformation; Dimethylnitrosamine; DNA; Lung; Male; Methylation; Neoplasms, Experimental; Organ Specificity; Rats | 1979 |
Occult blood testing using the guaiac method (haemoccult-test) for detection of tumorous lesions induced with 1,2-dimethyl-hydrazine and acetoxymethyl-methyl-nitrosamine in rats.
Topics: Adenocarcinoma; Animals; Colonic Neoplasms; Dimethylhydrazines; Dimethylnitrosamine; Guaiac; Male; Occult Blood; Rats | 1979 |
Selective induction of intestinal tumors in rats by methyl(acetoxymethyl)nitrosamine, an ester of the presumed reactive metabolite of dimethylnitrosamine.
Topics: Adenocarcinoma; Animals; Dimethylnitrosamine; Dose-Response Relationship, Drug; Female; Intestinal Neoplasms; Male; Neoplasms, Experimental; Nitrosamines; Rats; Sarcoma, Experimental; Sex Factors | 1977 |
Association between expression of transforming growth factor-alpha and progression of hepatocellular foci to neoplasms.
Topics: Adenoma; Animals; Carcinogens; Carcinoma; Cell Transformation, Neoplastic; Chrysenes; Dimethylnitrosamine; Glutathione Transferase; Liver Neoplasms, Experimental; Rats; Transforming Growth Factor alpha | 1992 |
Activating point mutation in Ki-ras codon 63 in a chemically induced rat renal tumor.
Topics: 3T3 Cells; Animals; Base Sequence; Carcinogens; Codon; Dimethylnitrosamine; Exons; Gene Expression Regulation, Neoplastic; Genes, ras; Kidney Neoplasms; Mice; Molecular Sequence Data; Mutation; Rats; Rats, Inbred F344 | 1992 |
Protective single/combined treatment with betel leaf and turmeric against methyl (acetoxymethyl) nitrosamine-induced hamster oral carcinogenesis.
Topics: Animals; Areca; beta Carotene; Carcinogens; Carotenoids; Cricetinae; Curcuma; Dimethylnitrosamine; Drug Screening Assays, Antitumor; Drug Therapy, Combination; Female; Mesocricetus; Mouth Neoplasms; Plant Extracts; Plants, Medicinal; Vitamin E | 1992 |
Participation of rat liver cytochrome P450 2E1 in the activation of N-nitrosodimethylamine and N-nitrosodiethylamine to products genotoxic in an acetyltransferase-overexpressing Salmonella typhimurium strain (NM2009).
Topics: Acetyltransferases; Animals; Biotransformation; Cytochrome P-450 CYP2E1; Cytochrome P-450 Enzyme System; Diethylnitrosamine; Dimethylnitrosamine; Hydroxylation; Male; Methylation; Microsomes, Liver; Nitroso Compounds; Oxidoreductases, N-Demethylating; Rats; Rats, Inbred Strains; Salmonella typhimurium | 1992 |
Treatment of chemically induced autochthonous rat mammary and colorectal carcinomas with interleukin-2.
Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carcinogens; Colorectal Neoplasms; Cyclophosphamide; Dimethylnitrosamine; Female; Interleukin-2; Male; Mammary Neoplasms, Experimental; Methylnitrosourea; Neoplasm Transplantation; Rats; Rats, Inbred Strains | 1991 |
Proliferation of carcinogen-damaged hepatocytes during cell-cycle-dependent initiation of hepatocarcinogenesis in the rat.
Topics: Animals; Carcinogens; Cell Cycle; Cocarcinogenesis; Deoxyguanosine; Dimethylnitrosamine; DNA Damage; DNA Repair; Guanine; Liver; Liver Neoplasms, Experimental; Liver Regeneration; Male; Rats; Rats, Inbred F344 | 1991 |
O6-methylguanine is a critical determinant of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone tumorigenesis in A/J mouse lung.
Topics: Animals; Carcinogens; Dimethylnitrosamine; DNA; Female; Guanine; Hydroxylation; Lung Neoplasms; Methylation; Mice; Nitrosamines | 1991 |
Possible role of acetaldehyde in ethanol-related rectal cocarcinogenesis in the rat.
Topics: Acetaldehyde; Animals; Carcinogens; Cocarcinogenesis; Cyanamide; Dimethylnitrosamine; Ethanol; Intestinal Mucosa; Male; Rats; Rats, Inbred Strains; Rectal Neoplasms; Rectum | 1990 |
Methylation of DNA by three N-nitroso compounds: evidence for sequence specific methylation by a common intermediate.
Topics: Base Sequence; Dimethylnitrosamine; DNA; DNA Restriction Enzymes; Guanine; Methylation; Methylnitrosourea; Nitrosamines; Nitroso Compounds; Plasmids; Polydeoxyribonucleotides | 1989 |
Infrequent activation of K-ras, H-ras, and other oncogenes in hepatocellular neoplasms initiated by methyl(acetoxymethyl)nitrosamine, a methylating agent, and promoted by phenobarbital in F344 rats.
Topics: Animals; Carcinogens; Dimethylnitrosamine; Female; Genes, ras; Liver Neoplasms, Experimental; Male; Nucleic Acid Hybridization; Phenobarbital; Proto-Oncogene Proteins; Proto-Oncogene Proteins p21(ras); Rats; Rats, Inbred F344; Transfection | 1989 |
Mutational specificities of environmental carcinogens in the lacI gene of Escherichia coli. I. The direct-acting analogue N-nitroso-N-methyl-N-alpha-acetoxymethylamine.
Topics: Base Composition; Base Sequence; Carcinogens; Cloning, Molecular; Dimethylnitrosamine; Environmental Pollution; Escherichia coli; Genes; Genes, Bacterial; Molecular Sequence Data; Mutagenicity Tests | 1989 |
Activation of the c-Ha-ras-1 proto-oncogene by methylation in vitro with alpha-acetoxy-N-nitrosodimethylamine.
Topics: Animals; Blotting, Southern; Carcinogenicity Tests; Cell Line; Cell Transformation, Neoplastic; Dimethylnitrosamine; DNA; DNA Mutational Analysis; DNA-Directed DNA Polymerase; Gene Amplification; Gene Expression Regulation; Genes, ras; Humans; Male; Methylation; Mice; Mice, Inbred CBA; Oligonucleotide Probes; Plasmids; Proto-Oncogene Mas; Taq Polymerase; Transfection | 1989 |
Transforming activity of DNA from rat liver tumors induced by the carcinogen methyl(acetoxymethyl)nitrosamine.
Topics: Animals; Blotting, Southern; Carcinogenicity Tests; Carcinogens; Cell Line; Cell Transformation, Neoplastic; Dimethylnitrosamine; DNA Restriction Enzymes; DNA, Neoplasm; Liver Neoplasms; Male; Mice; Mice, Nude; Molecular Weight; Proto-Oncogene Proteins; Proto-Oncogene Proteins p21(ras); Proto-Oncogenes; Rats; Transfection | 1988 |
Effects of SO2 or NOx on toxic and genotoxic properties of chemical carcinogens. II. Short term in vivo studies.
Topics: Air Pollutants; Alanine Transaminase; Alkaline Phosphatase; Animals; Aryl Hydrocarbon Hydroxylases; Aspartate Aminotransferases; Carcinogens; Cell Membrane Permeability; Cell Survival; Cytochrome P-450 CYP2E1; Dimethylnitrosamine; DNA Damage; gamma-Glutamyltransferase; L-Lactate Dehydrogenase; Liver; Lung; Nitrogen Oxides; Oxidoreductases, N-Demethylating; Rats; Sulfur Dioxide; Time Factors | 1988 |
Promotion by sodium barbital of renal cortical and transitional cell tumors, but not intestinal tumors, in F344 rats given methyl(acetoxymethyl)nitrosamine, and lack of effect of phenobarbital, amobarbital, or barbituric acid on development of either rena
Topics: Adenoma; Amobarbital; Animals; Barbital; Barbiturates; Carcinogens; Carcinoma; Carcinoma, Renal Cell; Carcinoma, Transitional Cell; Cocarcinogenesis; Dimethylnitrosamine; Intestinal Neoplasms; Kidney Neoplasms; Liver Neoplasms; Phenobarbital; Rats; Rats, Inbred F344; Thyroid Neoplasms | 1989 |
Comparative antitumor activity of ruthenium derivatives with 5'-deoxy-5-fluorouridine in chemically induced colorectal tumors in SD rats.
Topics: Adenocarcinoma; Animals; Colonic Neoplasms; Dimethylnitrosamine; Floxuridine; Imidazoles; Male; Organometallic Compounds; Rats; Rats, Inbred Strains; Rectal Neoplasms; Ruthenium | 1987 |
Quantitative relationship between initiation of hepatocarcinogenesis and induction of altered cell islands.
Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Animals; Benzopyrenes; Dimethylnitrosamine; DNA; Gamma Rays; Hepatectomy; Kinetics; Liver; Liver Neoplasms, Experimental; Liver Regeneration; Male; Neoplasms, Radiation-Induced; Phenobarbital; Rats; Rats, Inbred F344 | 1986 |
Inhibition of the metabolism of N-nitrosoacetoxymethylmethylamine in the rat by disulfiram.
Topics: Animals; Carbon Dioxide; Carbon Radioisotopes; Carcinogens; Depression, Chemical; Dimethylnitrosamine; Disulfiram; Esterases; Glutathione; Half-Life; Male; Rats; Rats, Inbred Strains | 1986 |
Phenobarbital-dependent proliferation of putative initiated rat hepatocytes.
Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Animals; Cell Division; Cells, Cultured; Dimethylnitrosamine; Liver; Liver Neoplasms, Experimental; Male; Phenobarbital; Rats; Rats, Inbred F344 | 1988 |
Acetoxymethyl-methylnitrosamine (AMMN) induced colorectal carcinogenesis is stimulated by chronic alcohol consumption.
Topics: Animals; Colonic Neoplasms; Dimethylnitrosamine; Drug Synergism; Ethanol; Male; Rats; Rats, Inbred Strains; Rectal Neoplasms | 1987 |
Effect of interleukin-2 on the manifestation and growth of acetoxymethyl-methylnitrosamine-induced colorectal rat adenocarcinoma.
Topics: Adenocarcinoma; Animals; Colonic Neoplasms; Dimethylnitrosamine; Immunotherapy; Interleukin-2; Lymphocyte Activation; Male; Rats; Rectal Neoplasms | 1986 |
Efficacy of beta-diketonato complexes of titanium, zirconium, and hafnium against chemically induced autochthonous colonic tumors in rats.
Topics: Animals; Body Weight; Carcinogens; Colonic Neoplasms; Dimethylnitrosamine; Hafnium; Male; Metals; Organometallic Compounds; Rats; Rats, Inbred Strains; Titanium; Zirconium | 1987 |
Activation of the human c-Ha-ras-1 proto-oncogene by in-vitro reaction with N-nitrosomethyl(acetoxymethyl)amine.
Topics: Animals; Carcinogens; Cell Line; Dimethylnitrosamine; DNA; Gene Expression Regulation; Humans; In Vitro Techniques; Methylation; Mice; Mice, Inbred CBA; Plasmids; Proto-Oncogene Mas; Proto-Oncogenes; Transfection | 1987 |
In vitro colonization ability appears soon after initiation of hepatocarcinogenesis in the rat.
Topics: Animals; Dimethylnitrosamine; Liver Neoplasms; Male; Phenobarbital; Rats; Rats, Inbred F344 | 1986 |
[Characteristics of the carcinogenic action of methyl(acetoxymethyl)nitrosamine and DNA repair in rats of different ages].
Topics: Aging; Animals; Carcinogens; Dimethylnitrosamine; DNA; DNA Repair; Female; Methylation; Methyltransferases; Neoplasms, Experimental; O(6)-Methylguanine-DNA Methyltransferase; Rats | 1986 |
Carcinogenicity of small doses of inhaled N-nitrosoacetoxymethyl-N-methylamine in Syrian golden hamsters.
Topics: Animals; Carcinoma; Carcinoma, Squamous Cell; Cricetinae; Dimethylnitrosamine; Dose-Response Relationship, Drug; Male; Mesocricetus; Nose Neoplasms; Time Factors | 1986 |
Different autochthonous models of colorectal cancer in the rat.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Animals; Colonic Neoplasms; Dimethylhydrazines; Dimethylnitrosamine; Disease Models, Animal; Methylnitronitrosoguanidine; Methylnitrosourea; Rats; Rectal Neoplasms | 1986 |
Influence of the carboxylesterase inhibitor bis-p-nitrophenylphosphate on the rates of hydrolysis of various alpha-esters of 1-(N-methyl-N-nitrosamino)-methanol in vitro and in vivo and on the acute toxicity and carcinogenicity of 1-(N-methyl-N-nitrosamin
Topics: Animals; Carboxylic Ester Hydrolases; Carcinogens; Dimethylnitrosamine; Dose-Response Relationship, Drug; Drug Interactions; Half-Life; Hydrolysis; Lethal Dose 50; Male; Neoplasms, Experimental; Nitrophenols; Rats; Rats, Inbred Strains; Time Factors | 1986 |
Metabolic nitrite formation from N-nitrosamines: are there other pathways than reductive denitrosation by cytochrome P-450?
Topics: Animals; Cytochrome P-450 Enzyme System; Dimethylnitrosamine; Female; Hypoxanthine; Hypoxanthines; Mice; Microsomes, Liver; NADP; Nitrites; Nitrosamines; Xanthine Oxidase | 1986 |
Autochthonous, acetoxymethylmethylnitrosamine-induced colorectal cancer in rats: a useful tool in selecting new active antineoplastic compounds?
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Carcinogens; Colonic Neoplasms; Dimethylnitrosamine; Dose-Response Relationship, Drug; Male; Organometallic Compounds; Rats; Rectal Neoplasms; Titanium | 1986 |
Cell cycle-dependent initiation of hepatocarcinogenesis in rats by methyl(acetoxymethyl)nitrosamine.
Topics: Animals; Carcinogens; Cell Cycle; Cell Division; Dimethylnitrosamine; DNA Repair; DNA Replication; Guanine; Hepatectomy; Hydrocortisone; Liver Neoplasms, Experimental; Male; Methylnitrosourea; Rats; Rats, Inbred F344; Time Factors | 1987 |
Paradoxical effect of dichlorobis(1-phenylbutane-1,3-dionato)molybdenum (IV), (Mo(bzac)2Cl2 on the growth of autochthonous chemically induced colorectal tumors in SD rats.
Topics: Animals; Antineoplastic Agents; Colonic Neoplasms; Dimethylnitrosamine; Male; Molybdenum; Organometallic Compounds; Rats; Rectal Neoplasms | 1987 |
Effect of age on DNA repair in carcinogenesis due to alkylating agents.
Topics: Age Factors; Aging; Alkylating Agents; Animals; Dimethylnitrosamine; DNA; DNA Repair; Liver; Methylation; Methyltransferases; Neoplasms, Experimental; O(6)-Methylguanine-DNA Methyltransferase; Rats | 1985 |
Synthesis, toxicity, and therapeutic efficacy of 4-amino-N-(2'-aminophenyl)-benzamide: a new compound preferentially active in slowly growing tumors.
Topics: Animals; Antineoplastic Agents; Cell Line; Dimethylnitrosamine; Dogs; Drug Evaluation, Preclinical; Female; Lethal Dose 50; Male; Methylnitrosourea; Mice; Mutagenicity Tests; Neoplasms, Experimental; Phenylenediamines; Rats; Rats, Inbred Strains; Time Factors | 1985 |
Embryotoxicity induced by alkylating agents: left-sided preponderance of paw malformations induced by acetoxymethyl-methylnitrosamine in mice.
Topics: Abnormalities, Drug-Induced; Alkylating Agents; Animals; Carcinogens; Dimethylnitrosamine; Female; Fingers; Foot Deformities, Congenital; Forelimb; Gestational Age; Hindlimb; Methylnitrosourea; Mice; Pregnancy | 1985 |
Quantitative relationship between hepatocytic neoplasms and islands of cellular alteration during hepatocarcinogenesis in the male F344 rat.
Topics: Animals; Carcinogens; Dimethylnitrosamine; Liver Neoplasms; Male; Phenobarbital; Rats; Rats, Inbred F344; Time Factors | 1985 |
[Effect of age on carcinogenesis in female rats induced by methyl (acetoxymethyl) nitrosamine].
Topics: Aging; Alkylation; Animals; Carcinogens; Dimethylnitrosamine; DNA, Neoplasm; Male; Methylation; Neoplasms, Experimental; Purines; Rats; Time Factors; Tissue Distribution | 1985 |
Chilli extract treatment and induction of eye lesions in hamsters.
Topics: Animals; Capsicum; Cricetinae; Dimethylnitrosamine; Eye; Female; Male; Mesocricetus; Plants, Edible; Plants, Medicinal; Vitamin A | 1985 |
In vitro formation of methyldiethyldithiocarbamate after the reaction of nitrosoacetoxymethylmethylamine or methylnitrosourea with disulfiram.
Topics: Animals; Biotransformation; Chemical Phenomena; Chemistry; Cytosol; Dimethylnitrosamine; Disulfiram; Ditiocarb; Drug Interactions; Liver; Male; Methylnitrosourea; Microsomes, Liver; Nitrosourea Compounds; Rats; Rats, Inbred Strains; Thiocarbamates | 1982 |
[Effect of local moderate hyperthermia in combination with N-nitroso-1,3-bis-(2-chloroethyl)urea (BCNU) and 5-fluoro-(tetrahydro-2-furyl)uracil (ftorafur) on induced autochthonous colonic cancers in the rat. 3: Polychemotherapy in combination with hyperth
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Carcinogens; Carmustine; Colon; Colonic Neoplasms; Combined Modality Therapy; Dimethylnitrosamine; Hyperthermia, Induced; Male; Prognosis; Rats; Rats, Inbred Strains; Tegafur | 1984 |
Nitrosamine-induced colonic carcinogenesis in rats after jejuno-ileal bypass.
Topics: Animals; Carcinogens; Colonic Neoplasms; Dimethylnitrosamine; Ileum; Jejunum; Male; Obesity; Random Allocation; Rats; Rats, Inbred Strains; Risk | 1984 |
The adenoma-carcinoma sequence in AMMN-induced colonic tumors of the rat.
Topics: Adenocarcinoma; Adenoma; Animals; Carcinogens; Carcinoma; Colonic Neoplasms; Dimethylnitrosamine; Endoscopy; Male; Rats; Rats, Inbred Strains; Rectal Neoplasms; Time Factors | 1984 |
Reduction of acetoxymethyl-methylnitrosamine-induced large bowel cancer in rats by indomethacin.
Topics: Animals; Dimethylnitrosamine; Indomethacin; Intestinal Neoplasms; Intestine, Large; Male; Rats; Rats, Inbred Strains | 1984 |
Evidence for penetration of the nuclear envelope by N-nitrosomethylhydroxymethylamine.
Topics: Animals; Biotransformation; Carcinogens; Cell Membrane Permeability; Dimethylnitrosamine; In Vitro Techniques; Liver; Nitrosamines; Nuclear Envelope; Rats | 1984 |
Stability of various alpha-esters of 1-(N-methyl-N-nitrosamino)-methanol in vitro and in vivo.
Topics: Animals; Carcinogens; Dimethylnitrosamine; Drug Stability; Esterases; Hydrolysis; Male; Rats; Rats, Inbred Strains | 1984 |
Treatment of autochthonous rat colonic adenocarcinomas with a thioether-lysophospholipid derivative in mono- and combination chemotherapy.
Topics: Adenocarcinoma; Administration, Oral; Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carcinogens; Carmustine; Colonic Neoplasms; Dimethylnitrosamine; Drug Administration Schedule; Fluorouracil; Injections, Intraperitoneal; Intestines; Male; Organ Size; Organophosphates; Organophosphorus Compounds; Phospholipid Ethers; Rats; Rats, Inbred Strains | 1984 |
Induction of oral mucosal tumors in hamsters and rats treated with methyl(acetoxymethyl)nitrosamine.
Topics: Animals; Carcinogens; Cheek; Cricetinae; Dimethylnitrosamine; Mouth Mucosa; Mouth Neoplasms; Rats; Tetradecanoylphorbol Acetate | 1984 |
Carcinogenicity of N-nitroso-acetoxymethyl-methylamine (acetoxymethyl-methylnitrosamine) after inhalation in rats.
Topics: Animals; Carcinogens; Dimethylnitrosamine; Dose-Response Relationship, Drug; Lung Neoplasms; Male; Neoplasms, Experimental; Rats; Rats, Inbred Strains | 1983 |
Chemotherapeutic studies on N-nitrosoacetoxymethyl-methylamine-and 1,2-dimethylhydrazine-induced colonic tumors in rats: monotherapy with 5-fluorouracil, ftorafur, CGP 6809, and CGP 15'720A.
Topics: 1,2-Dimethylhydrazine; Animals; Antineoplastic Agents; Carcinogens; Colonic Neoplasms; Dimethylhydrazines; Dimethylnitrosamine; Fluorouracil; Male; Methylhydrazines; Neoplasms, Experimental; Nitrosourea Compounds; Phenylurea Compounds; Rats; Rats, Inbred Strains; Tegafur | 1982 |
Influence of a non-synthetic diet with a high fat content on the local occurrence of colonic carcinomas induced by N-nitroso-acetoxymethylmethylamine (AMMN) in Sprague-Dawley Rats.
Topics: Animals; Colonic Neoplasms; Dietary Fats; Dimethylnitrosamine; Female; Male; Neoplasms, Experimental; Rats; Rats, Inbred Strains | 1983 |
Embryotoxicity induced by alkylating agents. Teratogenicity of acetoxymethyl-methylnitrosamine: dose-response relationship, application route dependency and phase specificity.
Topics: Alkylating Agents; Animals; Dimethylnitrosamine; Dose-Response Relationship, Drug; Embryo, Mammalian; Female; Fetus; Injections, Intraperitoneal; Injections, Intravenous; Injections, Subcutaneous; Maternal-Fetal Exchange; Mice; Pregnancy; Teratogens | 1983 |
Carcinogenesis and aging. II. Modifying effect of aging on metabolism of methyl(acetoxymethyl)nitrosamine and its interaction with DNA of various tissues in rats.
Topics: Aging; Animals; Carcinogens; Dimethylnitrosamine; DNA; Female; Intestinal Mucosa; Liver; Lung; Methylation; Rats; Uterus | 1983 |
Endocardial schwannomas in rats. Their characterization by light and electron microscopy.
Topics: Animals; Basement Membrane; Cell Membrane; Cell Nucleus; Dimethylnitrosamine; Endocardium; Heart Neoplasms; Male; Microscopy, Electron; Neoplasms, Experimental; Neurilemmoma; Rats; Reticulin | 1980 |
Endoscopic diagnosis of chemically induced autochthonous colonic tumors in rats.
Topics: Adenocarcinoma; Animals; Carcinogens; Colon; Colonic Neoplasms; Colonoscopy; Dimethylnitrosamine; Evaluation Studies as Topic; Hyperplasia; Intestinal Polyps; Male; Methylamines; Methylnitronitrosoguanidine; Methylnitrosourea; Rats | 1981 |
Photosuicide inactivation of acetylcholinesterase by nitrosamine derivatives.
Topics: Animals; Binding Sites; Binding, Competitive; Butyrylcholinesterase; Cholinesterase Inhibitors; Dimethylnitrosamine; Electrophorus; Horses; Kinetics; Nitrosamines; Photochemistry; Substrate Specificity | 1981 |
[Selective induction of tumors in Wistar rats with loop colostomy after administration of methyl-(acetoxymethyl)-nitrosamine (MAOMN) (author's transl)].
Topics: Adenocarcinoma; Adenoma; Animals; Carcinogens; Colonic Neoplasms; Colostomy; Dimethylnitrosamine; Female; Male; Neoplasms, Experimental; Papilloma; Rats; Time Factors | 1981 |
Metabolism of nitrosoacetoxymethylmethylamine in liver microsomes.
Topics: Animals; Carcinogens; Dimethylnitrosamine; Female; Formaldehyde; Half-Life; Hydrolysis; In Vitro Techniques; Kinetics; Methanol; Mice; Microsomes, Liver; NADP; Oxidation-Reduction | 1981 |
Stability of nitrosoacetoxymethylmethylamine in in vitro systems and in vivo and its excretion by the rat organism.
Topics: Animals; Carcinogens; Chemical Phenomena; Chemistry; Dimethylnitrosamine; Drug Stability; Half-Life; In Vitro Techniques; Kinetics; Male; Rats | 1980 |
Effect of disulfiram on acetoxymethyl-methyl-nitrosamine-induced tumors in rats.
Topics: Adenocarcinoma; Animals; Carcinoma, Squamous Cell; Dimethylnitrosamine; Disulfiram; Ear Neoplasms; Fibrosarcoma; Heart Neoplasms; Injections, Intravenous; Intubation, Gastrointestinal; Lung Neoplasms; Male; Neoplasms, Experimental; Peripheral Nervous System Neoplasms; Rats; Sarcoma | 1981 |
Adjuvant chemoprevention of experimental cancer: catechin and dietary turmeric in forestomach and oral cancer models.
Topics: Adjuvants, Pharmaceutic; Animals; Anticarcinogenic Agents; Benzo(a)pyrene; Catechin; Cricetinae; Curcumin; Diet; Dimethylnitrosamine; Female; Glutathione Transferase; Liver; Male; Mesocricetus; Mice; Mouth Neoplasms; Neoplasms, Experimental; Stomach Neoplasms | 1994 |
G to A transitions and G to T transversions in codon 12 of the Ki-ras oncogene isolated from mouse lung tumors induced by 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) and related DNA methylating and pyridyloxobutylating agents.
Topics: Adenine; Animals; Base Sequence; Carcinogens; Codon; Dimethylnitrosamine; DNA, Neoplasm; Female; Genes, ras; Guanine; Lung Neoplasms; Methylation; Mice; Mice, Inbred A; Nitrosamines; Point Mutation; Polymorphism, Restriction Fragment Length; Pyridines; Thymine | 1993 |
Low incidence of point mutations detected in the p53 tumor suppressor gene from chemically induced rat renal mesenchymal tumors.
Topics: Animals; Base Sequence; Dimethylnitrosamine; DNA Primers; Genes, p53; Kidney Neoplasms; Male; Molecular Sequence Data; Nickel; Point Mutation; Rats; Rats, Inbred F344; Sequence Analysis, DNA | 1994 |
Effect of benzo(a)pyrene and methyl(acetoxymethyl) nitrosamine on thymidine uptake and induction of aryl hydrocarbon hydroxylase activity in human fetal oesophageal cells in culture.
Topics: Aryl Hydrocarbon Hydroxylases; Benzo(a)pyrene; Carcinogens; Cells, Cultured; Dimethylnitrosamine; Enzyme Induction; Esophageal Neoplasms; Esophagus; Humans; Thymidine | 1993 |
Effects of cytosol on mutagenesis induced by N-nitrosodimethylamine, N-nitrosomethylurea and alpha-acetoxy-N-nitrosodimethylamine in different strains of Salmonella: evidence for different ultimate mutagens from N-nitrosodimethylamine.
Topics: Animals; Biotransformation; Carcinogens; Cricetinae; Cytosol; Dimethylnitrosamine; Dose-Response Relationship, Drug; Liver; Male; Mesocricetus; Methylnitrosourea; Microsomes, Liver; Mutagenesis; Mutagenicity Tests; Rats; Rats, Sprague-Dawley; Salmonella typhimurium; Species Specificity | 1993 |
Efficacy of dinaline and its methyl and acetyl derivatives against colorectal cancer in vivo and in vitro.
Topics: Animals; Antineoplastic Agents; Benzamides; Carcinogens; Colonic Neoplasms; Colorectal Neoplasms; Dimethylnitrosamine; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Male; Phenylenediamines; Rats; Rats, Sprague-Dawley; Tumor Cells, Cultured | 1996 |
Treatment of human cells with N-Nitroso(acetoxymethyl)methylamine: distribution patterns of piperidine-sensitive DNA damage at the nucleotide level of resolution are related to the sequence context.
Topics: Base Sequence; Carcinogens; Cells, Cultured; Dimethylnitrosamine; DNA; DNA Damage; DNA Footprinting; DNA Ligases; DNA Primers; Fibroblasts; Genes, jun; Genes, p53; Genes, ras; Humans; Methylnitrosourea; Molecular Sequence Data; Polymerase Chain Reaction; Skin | 1999 |
Interactions between methylating and pyridyloxobutylating agents in A/J mouse lungs: implications for 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced lung tumorigenesis.
Topics: Alkylating Agents; Animals; Carcinogens; Dimethylnitrosamine; DNA Methylation; DNA Repair; Drug Synergism; Female; Guanine; Liver; Lung; Lung Neoplasms; Mice; Mice, Inbred A; Nitrosamines; O(6)-Methylguanine-DNA Methyltransferase; Pyridines | 2001 |
Genotoxic methylating agents modulate extracellular signal regulated kinase activity through MEK-dependent, glutathione-, and DNA methylation-independent mechanisms in lung epithelial cells.
Topics: Animals; Cell Line, Transformed; Dimethylnitrosamine; DNA; DNA Methylation; Dose-Response Relationship, Drug; Glutathione; Lung; Methylnitrosourea; Mitogen-Activated Protein Kinases; Mutagens; Nitrosomethylurethane; Protein Serine-Threonine Kinases; Rats; Respiratory Mucosa | 2003 |
Endogenous 5-methylcytosine protects neighboring guanines from N7 and O6-methylation and O6-pyridyloxobutylation by the tobacco carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone.
Topics: 5-Methylcytosine; Base Sequence; Carcinogens; Chromatography, High Pressure Liquid; Deoxyguanosine; Dimethylnitrosamine; DNA Adducts; DNA Methylation; Genes, p53; Guanine; Hydrolysis; Nicotiana; Nitrosamines; Spectrometry, Mass, Electrospray Ionization | 2004 |
4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone, a component of tobacco smoke, modulates mediator release from human bronchial and alveolar epithelial cells.
Topics: Bronchi; Carcinogens; Cell Line; Chemokine CCL2; Cytokines; Dimethylnitrosamine; Dinoprostone; Epithelial Cells; Humans; Hydroxylation; Interleukin-6; Interleukin-8; Nitrosamines; Pulmonary Alveoli; Pyridines | 2005 |
Role of aldehydes in the toxic and mutagenic effects of nitrosamines.
Topics: Aldehydes; Animals; CHO Cells; Cricetinae; Cricetulus; Dimethylnitrosamine; DNA Adducts; DNA Damage; DNA Methylation; Humans; Models, Chemical; Mutagenicity Tests; Nitrosamines; Nitrosomethylurethane; O(6)-Methylguanine-DNA Methyltransferase; Pyrazines | 2013 |