Compounds > methoxychlor

methoxychlor and 1,1,1-trichloro-2-(4-hydroxyphenyl)-2-(4-methoxyphenyl)ethane

methoxychlor has been researched along with 1,1,1-trichloro-2-(4-hydroxyphenyl)-2-(4-methoxyphenyl)ethane in 5 studies

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (40.00)29.6817
2010's3 (60.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Gagne, PV; Hazai, E; Kupfer, D1
Flaws, JA; Gupta, RK; Miller, KP1
Craig, ZR; Flaws, JA; Gupta, RK; Hatfield, KP; Leslie, TC1
Basavarajappa, MS; Flaws, JA; Hernández-Ochoa, I; Paulose, T; Peretz, J1
Craig, ZR; Flaws, JA; Hannon, PR1

Other Studies

5 other study(ies) available for methoxychlor and 1,1,1-trichloro-2-(4-hydroxyphenyl)-2-(4-methoxyphenyl)ethane

ArticleYear
Glucuronidation of the oxidative cytochrome P450-mediated phenolic metabolites of the endocrine disruptor pesticide: methoxychlor by human hepatic UDP-glucuronosyl transferases.
    Drug metabolism and disposition: the biological fate of chemicals, 2004, Volume: 32, Issue:7

    Topics: Blotting, Western; Chromatography, Liquid; Cytochrome P-450 Enzyme System; Glucuronosyltransferase; Humans; Hydrocarbons, Chlorinated; In Vitro Techniques; Insecticides; Mass Spectrometry; Methoxychlor; Microsomes, Liver; Oxidation-Reduction; Phenols; Stereoisomerism; Time Factors

2004
Methoxychlor metabolites may cause ovarian toxicity through estrogen-regulated pathways.
    Toxicological sciences : an official journal of the Society of Toxicology, 2006, Volume: 93, Issue:1

    Topics: Animals; Estrogens; Female; Hydrocarbons, Chlorinated; Methoxychlor; Mice; Ovarian Follicle; Ovary; Phenols

2006
Mono-hydroxy methoxychlor alters levels of key sex steroids and steroidogenic enzymes in cultured mouse antral follicles.
    Toxicology and applied pharmacology, 2010, Dec-01, Volume: 249, Issue:2

    Topics: Androstenes; Animals; Cytochrome P-450 Enzyme System; Dimethyl Sulfoxide; Dose-Response Relationship, Drug; Estradiol; Female; Hydroxysteroid Dehydrogenases; In Vitro Techniques; Insecticides; Methoxychlor; Mice; Ovarian Follicle; Phosphoproteins; Progesterone; RNA, Messenger

2010
Increased sensitivity of estrogen receptor alpha overexpressing antral follicles to methoxychlor and its metabolites.
    Toxicological sciences : an official journal of the Society of Toxicology, 2011, Volume: 120, Issue:2

    Topics: Animals; Cell Size; Cells, Cultured; Cytochrome P-450 CYP1A2; Cytochrome P-450 Enzyme System; Cytochrome P450 Family 2; Estrogen Receptor alpha; Female; Gene Expression; Immunohistochemistry; Methoxychlor; Mice; Mice, Transgenic; Ovarian Follicle; Phenols; Reverse Transcriptase Polymerase Chain Reaction

2011
Pregnenolone co-treatment partially restores steroidogenesis, but does not prevent growth inhibition and increased atresia in mouse ovarian antral follicles treated with mono-hydroxy methoxychlor.
    Toxicology and applied pharmacology, 2013, Nov-01, Volume: 272, Issue:3

    Topics: Animals; Cells, Cultured; Female; Follicular Atresia; Gonadal Steroid Hormones; Growth Inhibitors; Humans; Insecticides; Methoxychlor; Mice; Ovarian Follicle; Pregnenolone; Treatment Outcome

2013