methoxyacetic acid has been researched along with phenyl acetate in 135 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 26 (19.26) | 18.7374 |
| 1990's | 50 (37.04) | 18.2507 |
| 2000's | 36 (26.67) | 29.6817 |
| 2010's | 20 (14.81) | 24.3611 |
| 2020's | 3 (2.22) | 2.80 |
| Authors | Studies |
|---|---|
| Creasy, DM; Gray, TJ; Moore, NP; Timbrell, JA | 1 |
| Drozhzhina, NA; Gurova, AI; Smoliar, NIa | 1 |
| Andrews, DL; Copeland, CB; Luebke, RW; Riddle, MM; Smialowicz, RJ; Williams, WC | 1 |
| McKinnell, C; Sharpe, RM | 2 |
| Clarke, DO; Duignan, JM; Welsch, F | 1 |
| Allenby, G; Foster, PM; Sharpe, RM | 2 |
| Clarke, DO; Mebus, CA; Stedman, DB; Welsch, F | 1 |
| Datu, AR; Rasjad, C; Yamashita, K; Yasuda, M | 2 |
| Andrews, DL; Copeland, CB; Luebke, RW; Riddle, MM; Rogers, RR; Smialowicz, RJ | 1 |
| Amendola, R; Bartoleschi, C; Cordelli, E; Emiliani, S; Julien, R; Petit, JM; Ratinaud, MH; Spanò, M | 1 |
| Allenby, G; Bartlett, JM; Sharpe, RM | 1 |
| Stedman, DB; Welsch, F | 1 |
| Mebus, CA; Welsch, F | 1 |
| Ratnasooriya, WD; Sharpe, RM | 1 |
| Groeseneken, D; Masschelein, R; Van Vlem, E; Veulemans, H | 3 |
| Fradkin, R; Nau, H; Scott, WJ; Wittfoht, W | 1 |
| Begley, KB; Cheever, KL; Richards, DE; Weigel, WW | 1 |
| Foster, PM; Williams, J | 1 |
| Nau, H; Scott, WJ; Wittfoht, W | 1 |
| Beattie, PJ; Brabec, MJ | 1 |
| Greene, JA; Sleet, RB; Welsch, F | 1 |
| Cheever, KL; Daniel, FB; Dinsmore, AM; Lal, JB; Richards, DE; Weigel, WW | 1 |
| Merker, HJ; Nau, H; Scott, WJ; Wittfoht, W | 1 |
| Blackburn, DM; Foster, PM; Lloyd, SC | 1 |
| Dean, JH; House, RV; Lauer, LD; Murray, MJ; Ward, EC | 1 |
| Randall, JL; Ritter, EJ; Ritter, JM; Scott, WJ | 1 |
| Cook, MW; Creasy, DM; Foster, PM; Gray, TJ; Moss, EJ; Thomas, LV; Walters, DG | 1 |
| Creasy, DM; Gangolli, SD; Gray, TJ; Moss, EJ | 1 |
| Brown, NA; Rawlings, SJ; Shuker, DE; Webb, M | 1 |
| Brown, NA; Holt, D; Webb, M | 1 |
| Beattie, PJ; Brabec, MJ; Welsh, MJ | 1 |
| Creasy, DM; Foster, JR; Foster, PM; Gray, TJ | 1 |
| DeBord, KE; Lowry, LK; Smallwood, AW | 1 |
| Brown, NA; Webb, M; Yonemoto, J | 1 |
| Brinkworth, MH; Nieschlag, E; Schlatt, S; Weinbauer, GF | 1 |
| Eisses, KT | 1 |
| Conolly, RB; Elswick, BA; Terry, KK; Welsch, F | 1 |
| Frayne, J; Greenfield, HM; Nicholson, HD | 1 |
| Comment, CE; Holladay, SD; Kwon, J; Luster, MI | 1 |
| Riddle, MM; Smialowicz, RJ; Williams, WC | 2 |
| Elswick, BA; Stedman, DB; Terry, KK; Welsch, F | 1 |
| Bremner, WJ; Millar, MR; Saunders, PT; Sharpe, RM | 1 |
| Butterfield, DA; Lee, J; Trad, CH | 1 |
| Khera, KS | 1 |
| Clarke, DO; Conolly, RB; Elswick, BA; Welsch, F | 1 |
| Maguire, SM; Millar, MR; Saunders, PT; Sharpe, RM | 1 |
| McKinnell, C; Millar, M; Sharpe, RM | 1 |
| Groeseneken, D; Masschelein, R; Steeno, O; Veulemans, H | 1 |
| Araki, T; Masuyama, Y; Sakai, T | 1 |
| Fennell, TR; Sumner, SC | 1 |
| Beliles, RP; McCandless, D; Nau, H; O'Flaherty, EJ; Schreiner, CM; Scott, WJ | 1 |
| Blumenthal, GM; Conolly, RB; Welsch, F | 1 |
| Almekinder, JL; Davis, BJ; Flagler, N; Maronpot, RR; Travlos, G; Wilson, R | 1 |
| de Wolff, FA; Kezić, S; Mahieu, K; Monster, AC | 1 |
| Chapin, RE; Li, LH; Miller, DS; Reece, JM; Smith, M; Wine, RN | 1 |
| Almekinder, JL; Davis, BJ; Lennard, DE; Walmer, DK | 1 |
| Clark, AM; Griswold, MD; Maguire, SM | 1 |
| Kim, BS; Smialowicz, RJ | 1 |
| Aarbakke, J; Aasmoe, L | 1 |
| Arashidani, K; Kawamoto, T; Kodama, Y | 1 |
| Fukushima, T; Homma, H; Imai, K; Iwatsubo, T; Lee, JA; Sakai, K; Santa, T; Tashiro, K | 1 |
| Hecht, NB; Syed, V | 1 |
| Loch-Caruso, R; Marty, MS | 1 |
| Bechter, R; Bobadilla, M; Meier, G; Suter, L | 1 |
| Carney, EW; Pitt, JA | 1 |
| Aasmoe, L; Mathiesen, M; Sager, G | 1 |
| Chen, CY; Chou, JS; Shih, TS; Smith, TJ | 1 |
| Chen, CY; Chou, JS; Liou, SH; Shih, TS | 1 |
| Blumenthal, GM; Conolly, RB; Elswick, BA; Gargas, ML; Hays, SM; Welsch, F | 1 |
| Jégou, B; Samson, M; Toppari, J; Yan, W | 1 |
| Corley, RA; Gargas, ML; Hays, SM; Mast, TJ; Paustenbach, DJ; Sweeney, LM; Tyler, TR; Weitz, KK | 1 |
| Balvers, M; Ivell, R; Pusch, W; Weinbauer, GF | 1 |
| Kido, T; Namiki, H | 1 |
| Kero, J; Suominen, J; Toppari, J; Yan, W | 1 |
| Cheever, KL; Conover, DL; DeBord, DG; Edwards, RM; Nelson, BK; Swearengin, TF; Werren, DW | 1 |
| Moore, HD; Peiris, LD | 1 |
| Aronow, B; Bailey, RW; Griswold, MD; Harmony, JA | 1 |
| Rao, AV; Shaha, C | 1 |
| Hayashi, K; Ichihara, G; Kojima, T; Murate, T; Nakade, Y; Shibata, E; Takagi, A; Takamatsu, J; Takeuchi, Y; Yamada, T | 1 |
| Breslin, WJ; Carney, EW; Dryzga, MD; Hansen, SC; Johnson, KA; Liberacki, AB; Pottenger, LH; Tornesi, B | 1 |
| Danielsen, M; Martinez, ED; Munell, F; Reventós, J; Rodriguez, OC; Selva, DM; Suárez-Quian, CA; Tirado, OM | 1 |
| Gloe, T; Ruyani, A; Sudarwati, S; Sumarsono, SH; Sutasurya, LA | 1 |
| Grossman, G; Jeyaraj, DA; Petrusz, P | 1 |
| BALIAKINA, MV; BASOVA, AK; MIKHAILOV, GS; ZHDANOVICH, ES | 1 |
| Aguanno, S; Barone, F; D'Agostino, A; D'Alessio, A | 1 |
| Afshari, CA; Jansen, MS; Lobenhofer, EK; McDonnell, DP; Miranda, PJ; Nagel, SC | 1 |
| Chan, H; Chang, HY; Chou, JS; Huang, YS; Lin, CC; Shih, TS | 1 |
| Cho, YB; Choi, HS; Park, JH; Song, JS | 1 |
| Aguanno, S; Barone, F; D'Agostino, A | 1 |
| Fischer, A; Hahn, C | 1 |
| Chung, JH; Kim, DJ; Ruyani, A; Sudarwati, S; Sumarsono, SH; Sutasurya, LA | 1 |
| Ikeda, N; Johyama, Y; Michitsuji, H; Yamada, S; Yokota, K | 1 |
| Chu, I; Poon, R; Valli, VE; Wade, M | 1 |
| Chu, I; Lee, A; Li, N; McMahon, A; Poon, R; Wade, MG | 1 |
| Henley, DV; Korach, KS | 1 |
| Chu, I; Li, N; Poon, R; Wade, MG | 1 |
| Anderson, GL; Funk, AB; Henderson, WM; Scofield, EH; Smith, MA | 1 |
| Cammenberg, M; Hult, K; Park, S | 1 |
| Li, W; Liu, X; Xu, R; Zhang, J; Zhang, Y | 1 |
| Ikeda, N; Johyama, Y; Michitsuji, H; Ueno, H; Yamada, S; Yokota, K | 1 |
| Du, LL; Li, BL; Wang, W; Zhang, ZG | 1 |
| Kawata, A; Wade, MG; Williams, A; Yauk, C | 1 |
| Bagchi, G; Hurst, CH; Waxman, DJ | 1 |
| Hou, WG; Li, Z; Liu, XP; Liu, XW; Shen, L; Yao, LB; Zhang, YQ; Zhao, J; Zhao, Y | 1 |
| Henley, DV; Korach, KS; Mueller, S | 1 |
| Curran, DP; Sui, B; Yeh, EA | 1 |
| Bagchi, G; Waxman, DJ; Zhang, Y | 1 |
| Elkin, ND; Piner, JA; Sharpe, RM | 1 |
| Luijten, M; Pennings, JL; Piersma, AH; Renkens, MF; Robinson, JF; van Beelen, VA; van Herwijnen, MH; Verhoef, A; Westerman, A | 1 |
| Bagchi, G; Stanley, KA; Waxman, DJ; Zhang, Y | 1 |
| Ishii, T; Kaul, SC; Priyandoko, D; Wadhwa, R | 1 |
| Hermsen, SA; Piersma, AH; Pronk, TE; van den Brandhof, EJ; van der Ven, LT | 1 |
| Budziszewska, B; Miranowicz-Dzierżawska, K; Starek, A; Starek-Świechowicz, B; Szymczak, W | 1 |
| Hou, W; Jian, B; Li, W; Sun, H; Wang, H; Yang, B; Yao, B; Yuan, J; Zhu, C | 1 |
| Dayan, C; Hales, BF | 1 |
| Hasegawa, R; Hayashi, M; Hirose, A; Ono, A; Sakuratani, Y; Tanaka, Y; Yamada, T; Yamazoe, Y | 1 |
| Bursová, M; Čabala, R; Coufal, P; Hložek, T | 1 |
| Liu, S; Parajuli, KR; You, Z; Zhang, Q | 1 |
| Fischer, K; Luch, A; Riebeling, C; Seiler, AE | 1 |
| Baker, TK; Durand, P; Goldstein, KM; Perrard, MH; Seyler, DE | 1 |
| Di Bona, KR; Ghaffari, R; Murphy, CJ; Richburg, JH; Stermer, AR; Voss, JJ | 1 |
| Botton, J; Charles, MA; Cordier, S; Garlantézec, R; Heude, B; Khoshnood, B; Labat, L; Le Gléau, F; Lelong, N; Monfort, C; Multigner, L; Pierre, F; Rouget, F; Slama, R; Warembourg, C | 1 |
| Bannier, E; Barillot, C; Binter, AC; Chevrier, C; Cordier, S; Ferré, JC; Monfort, C; Pelé, F; Saint-Amour, D; Simon, G | 1 |
| Williams, SJ | 1 |
| Bogaards, JJP; Braakman, RBH; Cnubben, NHP; Kelsey, JR; Smet, K; van Stee, LLP | 1 |
| Li, ASW; Marikawa, Y | 1 |
| Antonine, B; Guillaume, M; Marie-Hélène, P; Philippe, D | 1 |
1 review(s) available for methoxyacetic acid and phenyl acetate
| Article | Year |
|---|---|
Endocrine-disrupting chemicals use distinct mechanisms of action to modulate endocrine system function.
Topics: Acetates; Animals; Dibutyl Phthalate; Diethylstilbestrol; Endocrine Disruptors; Endocrine System; Female; Genistein; Genitalia, Female; Genitalia, Male; Humans; Male; Receptors, Cytoplasmic and Nuclear; Receptors, Estrogen | 2006 |
134 other study(ies) available for methoxyacetic acid and phenyl acetate
| Article | Year |
|---|---|
Urinary creatine profiles after administration of cell-specific testicular toxicants to the rat.
Topics: Acetates; Animals; Chromatography, High Pressure Liquid; Creatine; Dinitrobenzenes; Liver; Male; Mesylates; Phthalic Acids; Rats; Rats, Sprague-Dawley; Sertoli Cells | 1992 |
[The establishment of the MPEL for carboxylic acid derivatives in the air of a work area by using mathematical models].
Topics: Acetates; Acetoacetates; Air Pollutants, Occupational; Animals; Carboxylic Acids; Dose-Response Relationship, Drug; Guinea Pigs; Hydrocarbons, Chlorinated; Lethal Dose 50; Mathematics; Maximum Allowable Concentration; Mice; Models, Biological; Propionates; Rats | 1992 |
Differences between rats and mice in the immunosuppressive activity of 2-methoxyethanol and 2-methoxyacetic acid.
Topics: Acetates; Animals; Antibody Formation; Body Weight; Dose-Response Relationship, Drug; Ethylene Glycols; Female; Immune Tolerance; Lipopolysaccharides; Lymphocyte Activation; Mice; Mice, Inbred C57BL; Mitogens; Organ Size; Rats; Rats, Inbred F344; Species Specificity; Spleen; Thymus Gland | 1992 |
The role of specific germ cell types in modulation of the secretion of androgen-regulated proteins (ARPs) by stage VI-VIII seminiferous tubules from the adult rat.
Topics: Acetates; Animals; Cell Division; Culture Techniques; Electrophoresis, Gel, Two-Dimensional; Male; Proteins; Rats; Rats, Inbred Strains; Seminiferous Tubules; Spermatids; Spermatocytes; Spermatogenesis; Testosterone | 1992 |
2-Methoxyacetic acid dosimetry-teratogenicity relationships in CD-1 mice exposed to 2-methoxyethanol.
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Acetates; Animals; Dose-Response Relationship, Drug; Embryo, Mammalian; Ethylene Glycols; Metabolic Clearance Rate; Mice; Mice, Inbred Strains | 1992 |
Evaluation of changes in the secretion of immunoactive inhibin by adult rat seminiferous tubules in vitro as an indicator of early toxicant action on spermatogenesis.
Topics: Acetates; Animals; Body Fluids; Bucladesine; Culture Media; Culture Techniques; Dinitrobenzenes; Evaluation Studies as Topic; Follicle Stimulating Hormone; Germ Cells; Inhibins; Male; Radioimmunoassay; Rats; Rats, Inbred Strains; Seminiferous Tubules; Sertoli Cells; Spermatogenesis; Testis; Toluene; Toxicology | 1991 |
2-Methoxyethanol metabolism in pregnant CD-1 mice and embryos.
Topics: Acetates; Animals; Carbon Dioxide; Carbon Radioisotopes; Citric Acid Cycle; Embryo, Mammalian; Ethylene Glycols; Female; Male; Mice; Mice, Inbred Strains; Pregnancy; Pregnancy, Animal | 1992 |
Pathogenesis of limb malformations in mice induced by methoxyacetic acid.
Topics: Abnormalities, Drug-Induced; Acetates; Animals; Cell Death; Female; Limb Deformities, Congenital; Mice; Mice, Inbred ICR; Plasticizers; Pregnancy; Teratogens | 1991 |
Pattern of limb malformations in mice induced by methoxyacetic acid.
Topics: Abnormalities, Drug-Induced; Acetates; Animals; Female; Limb Deformities, Congenital; Mice; Mice, Inbred ICR; Plasticizers; Pregnancy; Teratogens | 1991 |
Evaluation of the immunotoxicity of orally administered 2-methoxyacetic acid in Fischer 344 rats.
Topics: Acetates; Animals; Body Weight; Erythrocytes; Ethylene Glycols; Hemolytic Plaque Technique; Immunity; Killer Cells, Natural; Lymphocytes; Male; Mitogens; Organ Size; Rats; Rats, Inbred F344; Sheep; Spleen; T-Lymphocytes | 1991 |
Evaluation of 2-methoxyacetic acid toxicity on mouse germ cells by flow cytometry.
Topics: Acetates; Animals; Energy Metabolism; Flow Cytometry; Male; Mice; Mice, Inbred C57BL; Mitochondria; Organ Size; Spermatids; Spermatocytes; Testis | 1991 |
Evidence that secretion of immunoactive inhibin by seminiferous tubules from the adult rat testis is regulated by specific germ cell types: correlation between in vivo and in vitro studies.
Topics: Acetates; Animals; Follicle Stimulating Hormone; Inhibins; Luteinizing Hormone; Male; Organ Culture Techniques; Radioimmunoassay; Rats; Rats, Inbred Strains; Reference Values; Seminiferous Tubules; Spermatocytes; Spermatozoa; Testis; Time Factors | 1991 |
Evidence for the control of testicular interstitial fluid volume in the rat by specific germ cell types.
Topics: Acetates; Animals; Extracellular Space; Follicle Stimulating Hormone; Hot Temperature; Luteinizing Hormone; Male; Organ Size; Rats; Rats, Inbred Strains; Spermatozoa; Testis | 1991 |
Inhibition of DNA synthesis in mouse whole embryo culture by 2-methoxyacetic acid and attenuation of the effects by simple physiological compounds.
Topics: Acetates; Animals; Cardiovascular System; Culture Techniques; DNA; Dose-Response Relationship, Drug; Embryo, Mammalian; Ethylene Glycols; Formates; Mice; Sarcosine; Teratogens; Thymidine | 1989 |
The possible role of one-carbon moieties in 2-methoxyethanol and 2-methoxyacetic acid-induced developmental toxicity.
Topics: Abnormalities, Drug-Induced; Acetates; Animals; Carbon; Ethylene Glycols; Female; Humans; Male; Mice; Oxidation-Reduction; Pregnancy; Sarcosine; Serine; Solvents; Toes | 1989 |
Evaluation of the effect of selective germ cell depletion on subsequent spermatogenesis and fertility in the rat.
Topics: Acetates; Animals; Fertility; Male; Rats; Rats, Inbred Strains; Seminiferous Tubules; Sperm Count; Spermatogenesis; Spermatozoa | 1989 |
Experimental human exposure to ethylene glycol monomethyl ether.
Topics: Acetates; Adult; Ethylene Glycols; Half-Life; Humans; Male; Respiration; Solvents | 1989 |
An improved method for the determination in urine of alkoxyacetic acids.
Topics: Acetates; Alkylation; Chromatography, Gas; Ethylene Glycols; Glycolates; Humans; Hydrogen-Ion Concentration; Solvents; Urine | 1989 |
Teratologic potential of 2-methoxyethanol and transplacental distribution of its metabolite, 2-methoxyacetic acid, in non-human primates.
Topics: Acetates; Animals; Body Weight; Dose-Response Relationship, Drug; Embryo, Mammalian; Ethylene Glycols; Female; Macaca fascicularis; Maternal-Fetal Exchange; Pregnancy; Solvents; Teratogens | 1989 |
The role of enzyme induction on metabolite formation of bis(2-methoxyethyl) ether in the rat.
Topics: Acetates; Animals; Biotransformation; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Induction; Ethylene Glycols; Male; Methyl Ethers; Phenobarbital; Rats; Rats, Inbred Strains; Sleep | 1989 |
The production of lactate and pyruvate as sensitive indices of altered rat Sertoli cell function in vitro following the addition of various testicular toxicants.
Topics: Acetates; Animals; Cells, Cultured; Diethylhexyl Phthalate; Dinitrobenzenes; Ethylene Glycols; Follicle Stimulating Hormone; Lactates; Lactic Acid; Male; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains; Sertoli Cells; Testis; Time Factors | 1988 |
Assay of methoxyacetic acid in body fluids and tissues by gas chromatography-mass spectrometry following tert.-butyldimethylsilylation.
Topics: Acetates; Animals; Embryo, Mammalian; Female; Gas Chromatography-Mass Spectrometry; Haplorhini; Indicators and Reagents; Organosilicon Compounds; Pregnancy; Silicon | 1988 |
Methoxyacetic acid and ethoxyacetic acid inhibit mitochondrial function in vitro.
Topics: Acetates; Animals; Ethylene Glycols; In Vitro Techniques; Male; Mitochondria; Mitochondria, Liver; Oxidative Phosphorylation; Oxygen Consumption; Rats; Rats, Inbred Strains; Testis | 1986 |
The relationship of embryotoxicity to disposition of 2-methoxyethanol in mice.
Topics: Abnormalities, Drug-Induced; Acetates; Aldehyde Dehydrogenase; Animals; Carbon Radioisotopes; Embryo, Mammalian; Ethanol; Ethylene Glycols; Female; Fomepizole; Male; Mice; Placenta; Pyrazoles | 1988 |
Metabolism of bis(2-methoxyethyl) ether in the adult male rat: evaluation of the principal metabolite as a testicular toxicant.
Topics: Acetates; Animals; Carbon Radioisotopes; Chromatography, High Pressure Liquid; Dealkylation; Ethylene Glycols; Male; Methyl Ethers; Rats; Rats, Inbred Strains; Testis | 1988 |
Ventral duplication of the autopod: chemical induction by methoxyacetic acid in rat embryos.
Topics: Abnormalities, Drug-Induced; Acetates; Animals; Embryo, Mammalian; Female; Foot; Foot Deformities, Congenital; Hindlimb; Maternal-Fetal Exchange; Microscopy, Electron, Scanning; Pregnancy; Rats | 1987 |
Comparison of the in vivo and in vitro testicular effects produced by methoxy-, ethoxy- and N-butoxy acetic acids in the rat.
Topics: Acetates; Animals; Glycolates; Male; Rats; Rats, Inbred Strains; Spermatocytes; Testis | 1987 |
Immunological studies in B6C3F1 mice following exposure to ethylene glycol monomethyl ether and its principal metabolite methoxyacetic acid.
Topics: Acetates; Animals; Antibody Formation; Bone Marrow; Ethylene Glycols; Female; Hemolytic Plaque Technique; Immunity; Immunity, Cellular; Immunity, Innate; Lymphatic System; Macrophages; Mice; Spleen; Thymus Gland | 1985 |
Gas chromatographic determination of methoxyacetic and ethoxyacetic acid in urine.
Topics: Acetates; Chromatography, Gas; Environmental Exposure; Ethylene Glycols; Humans | 1986 |
Teratogenicity of dimethoxyethyl phthalate and its metabolites methoxyethanol and methoxyacetic acid in the rat.
Topics: Abnormalities, Drug-Induced; Acetates; Animals; Dose-Response Relationship, Drug; Embryo, Mammalian; Ethylene Glycols; Female; Fingers; Heart Defects, Congenital; Hydronephrosis; Limb Deformities, Congenital; Phthalic Acids; Pregnancy; Rats; Rats, Inbred Strains; Toes | 1985 |
The role of metabolism in 2-methoxyethanol-induced testicular toxicity.
Topics: Acetates; Animals; Chromatography, High Pressure Liquid; Disulfiram; Ethylene Glycols; Gas Chromatography-Mass Spectrometry; Male; Mass Spectrometry; Pyrazoles; Rats; Rats, Inbred Strains; Seminiferous Tubules; Testis | 1985 |
Studies on the toxicity of some glycol ethers and alkoxyacetic acids in primary testicular cell cultures.
Topics: Acetates; Animals; Carnitine O-Acetyltransferase; Cells, Cultured; Ethylene Glycols; L-Lactate Dehydrogenase; Male; Rats; Rats, Inbred Strains; Sertoli Cells; Spermatocytes; Spermatogonia; Spermatozoa; Testis | 1985 |
The teratogenic potential of alkoxy acids in post-implantation rat embryo culture: structure-activity relationships.
Topics: Abnormalities, Drug-Induced; Acetates; Animals; Embryo, Mammalian; Female; Male; Organ Culture Techniques; Pregnancy; Rats; Structure-Activity Relationship | 1985 |
The teratogenicity of methoxyacetic acid in the rat.
Topics: Abnormalities, Drug-Induced; Acetates; Animals; Female; Fetal Resorption; Fetus; Gestational Age; Injections, Intraperitoneal; Maternal-Fetal Exchange; Pregnancy; Rats; Rats, Inbred Strains | 1984 |
The effect of 2-methoxyethanol and methoxyacetic acid on Sertoli cell lactate production and protein synthesis in vitro.
Topics: Acetates; Animals; Ethylene Glycols; Lactates; Lactic Acid; Male; Protein Biosynthesis; Rats; Rats, Inbred Strains; Sertoli Cells; Spermatogenesis | 1984 |
Testicular toxicity produced by ethylene glycol monomethyl and monoethyl ethers in the rat.
Topics: Acetates; Animals; Biotransformation; Cells, Cultured; Disulfiram; Ethylene Glycols; Male; Organ Size; Pargyline; Pyrazoles; Rats; Seminiferous Tubules; Testicular Diseases; Testis; Time Factors; Tissue Distribution | 1984 |
Analyses of ethylene glycol monoalkyl ethers and their proposed metabolites in blood and urine.
Topics: Acetates; Chemical Phenomena; Chemistry; Chromatography, Gas; Ethylene Glycols; Fluorobenzenes; Humans | 1984 |
Effects of dimethoxyethyl phthalate, monomethoxyethyl phthalate, 2-methoxyethanol and methoxyacetic acid on post implantation rat embryos in culture.
Topics: Acetates; Animals; Embryo, Mammalian; Ethylene Glycols; Gestational Age; Organ Culture Techniques; Phthalic Acids; Rats; Rats, Inbred Strains | 1984 |
Identification of male germ cells undergoing apoptosis in adult rats.
Topics: Acetates; Animals; Apoptosis; Follicle Stimulating Hormone; Gonadotropin-Releasing Hormone; Male; Rats; Rats, Sprague-Dawley; Spermatogenesis; Spermatozoa; Staining and Labeling; Testis; Testosterone | 1995 |
Differences in teratogenic and toxic properties of alcohol dehydrogenase inhibitors pyrazole and 4-methylpyrazole in Drosophila melanogaster: I. ADH allozymes in variable genetic backgrounds.
Topics: Acetates; Alcohol Dehydrogenase; Animals; Drosophila melanogaster; Drug Synergism; Female; Fomepizole; Larva; Male; Pyrazoles | 1995 |
Development of a physiologically based pharmacokinetic model describing 2-methoxyacetic acid disposition in the pregnant mouse.
Topics: Acetates; Animals; Embryonic and Fetal Development; Female; Fetus; Mice; Mice, Inbred Strains; Models, Biological; Placenta; Pregnancy; Pregnancy, Animal; Regional Blood Flow | 1995 |
The effect of germ cell complement on the presence of oxytocin in the interstitial and seminiferous tubule fluid of the rat testis.
Topics: Acetates; Animals; Extracellular Space; Hot Temperature; Male; Oxytocin; Rats; Rats, Wistar; Semen; Seminiferous Epithelium; Spermatocytes | 1994 |
Fetal hematopoietic alterations after maternal exposure to ethylene glycol monomethyl ether: prolymphoid cell targeting.
Topics: Acetates; Animals; Antigens, Surface; CD28 Antigens; CD4-CD8 Ratio; Cell Division; Cell Survival; Embryonic and Fetal Development; Environmental Pollutants; Erythrocytes; Ethylene Glycols; Female; Flow Cytometry; Gene Expression Regulation, Developmental; Gestational Age; Hematopoiesis; Immunosuppression Therapy; Liver; Male; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Placenta; Pregnancy; Prenatal Exposure Delayed Effects; Solvents; Thymus Gland | 1994 |
Species and strain comparisons of immunosuppression by 2-methoxyethanol and 2-methoxyacetic acid.
Topics: Acetates; Animals; Ethylene Glycols; Female; Immune Tolerance; Immunosuppressive Agents; Lipopolysaccharides; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Inbred Strains; Rats; Rats, Inbred F344; Rats, Inbred Lew; Rats, Inbred Strains; Rats, Inbred WF; Rats, Sprague-Dawley; Species Specificity | 1994 |
Developmental phase alters dosimetry-teratogenicity relationship for 2-methoxyethanol in CD-1 mice.
Topics: Abnormalities, Drug-Induced; Acetates; Animals; Biotransformation; Brain; Dose-Response Relationship, Drug; Embryonic and Fetal Development; Ethylene Glycols; Female; Fetal Death; Gestational Age; Infusion Pumps; Infusions, Parenteral; Injections, Intravenous; Male; Mice; Mice, Inbred Strains; Morphogenesis; Neural Tube Defects; Pregnancy; Ribs; Skull; Spine | 1994 |
Immunohistochemical localization of androgen receptors in the rat testis: evidence for stage-dependent expression and regulation by androgens.
Topics: Acetates; Aging; Androgens; Animals; Immunohistochemistry; Male; Mesylates; Rats; Rats, Sprague-Dawley; Receptors, Androgen; Reference Values; Spermatogenesis; Testis; Tissue Distribution | 1994 |
Electron paramagnetic resonance studies of the effects of methoxyacetic acid, a teratologic toxin, on human erythrocyte membranes.
Topics: Acetates; Carbohydrates; Cytoskeletal Proteins; Dose-Response Relationship, Drug; Electron Spin Resonance Spectroscopy; Erythrocyte Membrane; Humans; Lipid Bilayers; Membrane Proteins; Structure-Activity Relationship; Teratogens | 1993 |
Mouse placenta: hemodynamics in the main maternal vessel and histopathologic changes induced by 2-methoxyethanol and 2-methoxyacetic acid following maternal dosing.
Topics: Acetates; Animals; Ethylene Glycols; Female; Fetal Diseases; Fibrin; Hemodynamics; Hemorrhage; Mice; Placenta; Pregnancy; Pregnancy Complications, Cardiovascular; Regional Blood Flow; Uterine Hemorrhage | 1993 |
Pharmacokinetics of 2-methoxyethanol and 2-methoxyacetic acid in the pregnant mouse: a physiologically based mathematical model.
Topics: Acetates; Animals; Ethylene Glycols; Female; Mice; Models, Biological; Organ Size; Pregnancy; Tissue Distribution | 1993 |
Stage-dependent expression of mRNA for cyclic protein 2 during spermatogenesis is modulated by elongate spermatids.
Topics: Acetates; Animals; Base Sequence; Cathepsin L; Cathepsins; Cell Communication; Cysteine Endopeptidases; DNA; Endopeptidases; Enzyme Induction; Male; Molecular Sequence Data; Rats; Rats, Wistar; RNA, Messenger; Sertoli Cells; Spermatids; Spermatocytes; Spermatogenesis; Testis | 1993 |
Relative roles of testosterone and the germ cell complement in determining stage-dependent changes in protein secretion by isolated rat seminiferous tubules.
Topics: Acetates; Animals; Clusterin; Culture Techniques; Glycoproteins; Male; Mesylates; Molecular Chaperones; Organ Size; Rats; Rats, Wistar; Seminiferous Tubules; Spermatogenesis; Testis; Testosterone | 1993 |
Exposure to ethylene glycol ethers and spermatogenic disorders in man: a case-control study.
Topics: Acetates; Adult; Case-Control Studies; Ethylene Glycols; Humans; Infertility, Male; Male; Middle Aged; Occupational Exposure; Sperm Count; Sperm Motility; Spermatogenesis | 1993 |
Determination of urinary alkoxyacetic acids by a rapid and simple method for biological monitoring of workers exposed to glycol ethers and their acetates.
Topics: Acetates; Adult; Environmental Monitoring; Ethylene Glycols; Female; Humans; Occupational Exposure; Solvents | 1993 |
A possible mechanism for the formation of 14CO2 via 2-methoxyacetic acid in mice exposed to 14C-labeled 2-methoxyethanol.
Topics: Acetates; Animals; Carbon Dioxide; Carbon Radioisotopes; Ethylene Glycols; Mice; Models, Chemical | 1993 |
Physiologically based pharmacokinetics of methoxyacetic acid: dose-effect considerations in C57BL/6 mice.
Topics: Abnormalities, Drug-Induced; Acetates; Animals; Computer Simulation; Dose-Response Relationship, Drug; Embryo, Mammalian; Female; Fetus; Image Processing, Computer-Assisted; Immunosuppressive Agents; Injections, Intraperitoneal; Limb Buds; Maternal-Fetal Exchange; Mice; Mice, Inbred C57BL; Models, Biological; Pregnancy; Tissue Distribution | 1995 |
Physiologically based pharmacokinetic models applicable to organogenesis: extrapolation between species and potential use in prenatal toxicity risk assessments.
Topics: Acetates; Animals; Ethylene Glycols; Female; Fetus; Humans; Models, Biological; Pregnancy; Pregnancy, Animal; Risk Assessment | 1995 |
Repeated high dose oral exposure or continuous subcutaneous infusion of 2-methoxyacetic acid does not suppress humoral immunity in the mouse.
Topics: Acetates; Administration, Oral; Animals; Antibody Formation; Antigens, T-Independent; Biological Availability; Dose-Response Relationship, Drug; Erythrocytes; Female; Hemolytic Plaque Technique; Immunosuppressive Agents; Infusion Pumps, Implantable; Injections, Subcutaneous; Lipopolysaccharides; Mice; Organ Size; Osmolar Concentration; Rats; Rats, Inbred F344; Sheep; Species Specificity; Spleen; Thymus Gland | 1996 |
Ovarian luteal cell toxicity of ethylene glycol monomethyl ether and methoxy acetic acid in vivo and in vitro.
Topics: Acetates; Administration, Oral; Animals; Cells, Cultured; Corpus Luteum; Estradiol; Estrus; Ethylene Glycols; Female; Follicle Stimulating Hormone; Immunosuppressive Agents; Luteinizing Hormone; Progesterone; Rats; Rats, Sprague-Dawley; Solvents; Vagina | 1997 |
Dermal absorption of vaporous and liquid 2-methoxyethanol and 2-ethoxyethanol in volunteers.
Topics: Acetates; Administration, Cutaneous; Administration, Inhalation; Adult; Chromatography, Gas; Ethylene Glycols; Female; Humans; Male; Skin Absorption; Solvents | 1997 |
Reproductive toxicology. Methoxyacetic acid.
Topics: Acetates; Animals; Birth Weight; Body Weight; Dose-Response Relationship, Drug; Drinking; Female; Fertility; Kidney; Litter Size; Liver; Male; Mice; Organ Size; Pregnancy; Reproduction; Sperm Count; Sperm Motility; Spermatozoa; Testis | 1997 |
Protection against methoxyacetic-acid-induced spermatocyte apoptosis with calcium channel blockers in cultured rat seminiferous tubules: possible mechanisms.
Topics: 4-Aminopyridine; Acetates; Animals; Apoptosis; Calcium; Calcium Channel Blockers; Male; Potassium Channel Blockers; Rats; Rats, Sprague-Dawley; Seminiferous Tubules; Spermatocytes; Tetraethylammonium; Tetraethylammonium Compounds | 1997 |
Toxicity of methoxyacetic acid in cultured human luteal cells.
Topics: Acetates; Animals; Cells, Cultured; Cyclic AMP; Ethylene Glycols; Female; Granulosa Cells; Humans; Hydrogen-Ion Concentration; Ovary; Progesterone; Radioimmunoassay; Rats; Solvents | 1997 |
Accumulation of clusterin/sulfated glycoprotein-2 in degenerating pachytene spermatocytes of adult rats treated with methoxyacetic acid.
Topics: Acetates; Animals; Blotting, Northern; Cell Survival; Cells, Cultured; Clusterin; DNA Fragmentation; Glycoproteins; Immunohistochemistry; In Situ Hybridization; Male; Molecular Chaperones; Rats; Rats, Sprague-Dawley; RNA, Messenger; Spermatocytes | 1997 |
Regulation of the secretion and synthesis of rat Sertoli cell SGP-1, SGP-2 and CP-2 by elongate spermatids.
Topics: Acetates; Animals; Cathepsin L; Cathepsins; Clusterin; Cysteine Endopeptidases; Endopeptidases; Enzyme Precursors; Epithelium; Glycoproteins; Male; Molecular Chaperones; Protein Precursors; Rats; Rats, Sprague-Dawley; Rats, Wistar; Saposins; Seminiferous Tubules; Sertoli Cells; Spermatids; Spermatogenesis | 1997 |
The role of metabolism in 2-methoxyethanol-induced suppression of in vitro polyclonal antibody responses by rat and mouse lymphocytes.
Topics: Acetaldehyde; Acetates; Animals; Antibody Formation; B-Lymphocytes; Cells, Cultured; Coculture Techniques; Ethylene Glycols; Female; Immunoglobulin G; Immunoglobulin M; Immunosuppressive Agents; Liver; Mice; Rats; Rats, Inbred F344; Species Specificity | 1997 |
Gender difference in the elimination of 2-methoxyethanol, methoxyacetic acid and ethoxyacetic acid in rat.
Topics: Acetates; Alcohol Dehydrogenase; Animals; Ethylene Glycols; Female; Half-Life; Immunosuppressive Agents; Male; Rats; Rats, Wistar; Sex Characteristics; Solvents | 1997 |
Induction of sister-chromatid exchange by ethylene glycol monomethylether and its metabolite.
Topics: Acetates; Animals; Bone Marrow; Ethylene Glycols; Female; Humans; Lymphocytes; Male; Mice; Mutagens; Sister Chromatid Exchange | 1998 |
Localization of D-aspartic acid in elongate spermatids in rat testis.
Topics: Acetates; Amino Acids; Animals; Aspartic Acid; Cytoplasm; Epididymis; Immunohistochemistry; Male; Mesylates; Rats; Rats, Sprague-Dawley; Seminiferous Tubules; Sertoli Cells; Spermatids; Spermatozoa; Testis | 1998 |
Rat pachytene spermatocytes down-regulate a polo-like kinase and up-regulate a thiol-specific antioxidant protein, whereas sertoli cells down-regulate a phosphodiesterase and up-regulate an oxidative stress protein after exposure to methoxyethanol and met
Topics: Acetates; Amino Acid Sequence; Animals; Antioxidants; Base Sequence; Cells, Cultured; Ethylene Glycols; Gene Expression Regulation; Heat-Shock Proteins; Male; Molecular Sequence Data; Oxidative Stress; Peroxidases; Peroxiredoxins; Phosphoric Diester Hydrolases; Protein Serine-Threonine Kinases; Proteins; Rats; Rats, Sprague-Dawley; RNA, Messenger; Sequestosome-1 Protein; Sertoli Cells; Spermatocytes | 1998 |
2-Methoxyethanol inhibits gap junctional communication in rat myometrial myocytes.
Topics: Acetates; Animals; Cell Communication; Cells, Cultured; Ethylene Glycols; Female; Fluorescent Dyes; Gap Junctions; Isoquinolines; Myometrium; Rats; Time Factors | 1998 |
Flow cytometry as a sensitive tool to assess testicular damage in rat.
Topics: Acetates; Administration, Oral; Animals; Epididymis; Flow Cytometry; Male; Organ Size; Rats; Rats, Wistar; Sensitivity and Specificity; Sperm Head; Testis; Toxicity Tests | 1998 |
Evaluation of various toxicants in rabbit whole-embryo culture using a new morphologically-based evaluation system.
Topics: 6-Aminonicotinamide; Acetates; Animals; Culture Techniques; Dose-Response Relationship, Drug; Embryo, Mammalian; Ethanol; Female; Penicillin G; Rabbits; Somites; Teratogens | 1999 |
Elimination of methoxyacetic acid and ethoxyacetic acid in rat.
Topics: Acetates; Animals; Female; Kinetics; Male; Rats; Rats, Wistar; Sex Factors; Time Factors | 1999 |
Improved method to measure urinary alkoxyacetic acids.
Topics: Acetates; Environmental Monitoring; Gas Chromatography-Mass Spectrometry; Glycolates; Humans; Hydrogen-Ion Concentration; Occupational Exposure; Reference Values; Reproducibility of Results; Sensitivity and Specificity; Specimen Handling | 1999 |
Correlation between urinary 2-methoxy acetic acid and exposure of 2-methoxy ethanol.
Topics: Acetates; China; Chromatography, Gas; Environmental Monitoring; Ethylene Glycols; Gas Chromatography-Mass Spectrometry; Humans; Occupational Exposure; Teratogens | 1999 |
Development of a physiologically based pharmacokinetic model of 2-methoxyethanol and 2-methoxyacetic acid disposition in pregnant rats.
Topics: Acetates; Animals; Body Fluid Compartments; Body Weight; Dose-Response Relationship, Drug; Embryo, Mammalian; Ethylene Glycols; Female; Mammary Glands, Animal; Mice; Models, Biological; Organ Size; Placenta; Pregnancy; Pregnancy, Animal; Rats; Teratogens; Tissue Distribution | 2000 |
Bcl-w forms complexes with Bax and Bak, and elevated ratios of Bax/Bcl-w and Bak/Bcl-w correspond to spermatogonial and spermatocyte apoptosis in the testis.
Topics: Acetates; Animals; Apoptosis; Apoptosis Regulatory Proteins; bcl-2 Homologous Antagonist-Killer Protein; bcl-2-Associated X Protein; Follicle Stimulating Hormone; Gene Expression Regulation, Developmental; Leydig Cells; Macromolecular Substances; Male; Membrane Proteins; Mesylates; Mice; Mice, Knockout; Proteins; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley; RNA, Messenger; Sertoli Cells; Spermatocytes; Spermatogonia; Subcellular Fractions; Testis; Testosterone | 2000 |
A toxicokinetic study of inhaled ethylene glycol monomethyl ether (2-ME) and validation of a physiologically based pharmacokinetic model for the pregnant rat and human.
Topics: Acetates; Animals; Ethylene Glycols; Female; Humans; Immunosuppressive Agents; Inhalation Exposure; Models, Biological; Predictive Value of Tests; Pregnancy; Radiotherapy Planning, Computer-Assisted; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Teratogens | 2000 |
The rat endozepine-like peptide gene is highly expressed in late haploid stages of male germ cell development.
Topics: Acetates; Animals; Carrier Proteins; Diazepam Binding Inhibitor; Gene Expression; Haploidy; Immunohistochemistry; Male; Rats; Rats, Wistar; RNA, Messenger; Spermatids; Spermatozoa; Testis | 2000 |
Expression of testicular fatty acid-binding protein PERF 15 during germ cell apoptosis.
Topics: Acetates; Animals; Antibodies, Monoclonal; Apoptosis; Carrier Proteins; Electrophoresis, Polyacrylamide Gel; Fatty Acid-Binding Proteins; Fluorescent Antibody Technique, Indirect; Germ Cells; Immunohistochemistry; Immunosuppressive Agents; In Situ Nick-End Labeling; Injections, Intraperitoneal; Male; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Wistar; Spermatogenesis; Testis | 2000 |
Differential expression and regulation of the retinoblastoma family of proteins during testicular development and spermatogenesis: roles in the control of germ cell proliferation, differentiation and apoptosis.
Topics: Acetates; Animals; Apoptosis; Cell Differentiation; Cell Division; Gene Expression Regulation; Male; Mesylates; Multigene Family; Nuclear Proteins; Phosphoproteins; Phosphorylation; Proteins; Rats; Rats, Sprague-Dawley; Retinoblastoma Protein; Retinoblastoma-Like Protein p130; Seminiferous Tubules; Spermatocytes; Spermatogenesis; Testis | 2001 |
2-Methoxyethanol metabolism, embryonic distribution, and macromolecular adduct formation in the rat: the effect of radiofrequency radiation-induced hyperthermia.
Topics: Acetates; Animals; Biomarkers; Chromatography, High Pressure Liquid; Embryo, Mammalian; Ethylene Glycols; Female; Fever; Gas Chromatography-Mass Spectrometry; Kinetics; Macromolecular Substances; Male; Pregnancy; Radio Waves; Rats; Rats, Sprague-Dawley; Teratogens | 2001 |
Effects of acute and chronic doses of methoxy acetic acid on hamster sperm fertilising ability.
Topics: Acetates; Animals; Benzimidazoles; Cricetinae; Fertilization in Vitro; Fluorescent Dyes; Immunosuppressive Agents; Male; Mesocricetus; Spermatogenesis; Spermatozoa; Testis | 2001 |
Heat shock-initiated apoptosis is accelerated and removal of damaged cells is delayed in the testis of clusterin/ApoJ knock-out mice.
Topics: Acetates; Animals; Apoptosis; Clusterin; Cytoplasm; DNA Fragmentation; Female; Glycoproteins; Hot Temperature; Immunohistochemistry; In Situ Nick-End Labeling; Male; Mice; Mice, Knockout; Molecular Chaperones; Organ Size; Sertoli Cells; Sperm Count; Spermatogenesis; Spermatozoa; Testis | 2002 |
N-acetylcysteine prevents MAA induced male germ cell apoptosis: role of glutathione and cytochrome c.
Topics: Acetates; Acetylcysteine; Animals; Antioxidants; Apoptosis; Caspase 3; Caspase 9; Caspases; Cytochrome c Group; Enzyme Activation; Germ Cells; Glutathione; Lipid Peroxidation; Mitochondria; Oxidation-Reduction; Rats; Reactive Oxygen Species | 2002 |
Involvement of caspase 3 mediated apoptosis in hematopoietic cytotoxicity of metabolites of ethylene glycol monomethyl ether.
Topics: Acetaldehyde; Acetates; Apoptosis; Caspase 3; Caspases; Ethylene Glycols; Hematopoietic Stem Cells; HL-60 Cells; Humans; In Vitro Techniques; Japan; Male | 2002 |
Significance of 2-methoxypropionic acid formed from beta-propylene glycol monomethyl ether: integration of pharmacokinetic and developmental toxicity assessments in rabbits.
Topics: Abnormalities, Drug-Induced; Acetates; Administration, Oral; Animals; Area Under Curve; Dose-Response Relationship, Drug; Embryo, Mammalian; Embryonic and Fetal Development; Female; Fetal Viability; No-Observed-Adverse-Effect Level; Organ Culture Techniques; Pregnancy; Propionates; Propylene Glycols; Rabbits; Teratogens; Tissue Distribution | 2003 |
Methoxyacetic acid disregulation of androgen receptor and androgen-binding protein expression in adult rat testis.
Topics: Acetates; Androgen-Binding Protein; Androgens; Animals; Apoptosis; Cell Line; Dihydrotestosterone; Dissection; Drug Synergism; Immunohistochemistry; Lasers; Male; Meiosis; Mice; Rats; Rats, Sprague-Dawley; Receptors, Androgen; RNA, Messenger; Spermatocytes; Testis; Tissue and Organ Harvesting | 2003 |
The laminin binding protein p40 is involved in inducing limb abnormality of mouse fetuses as the effects of methoxyacetic acid treatment.
Topics: Acetates; Amino Acid Sequence; Animals; Blotting, Western; Carrier Proteins; Electrophoresis; Electrophoresis, Polyacrylamide Gel; Embryonic and Fetal Development; Female; Forelimb; Laminin; Male; Mice; Molecular Sequence Data; Pregnancy | 2003 |
Dynamics of testicular germ cell apoptosis in normal mice and transgenic mice overexpressing rat androgen-binding protein.
Topics: Acetates; Age Factors; Androgen-Binding Protein; Animals; Apoptosis; Cell Division; Gene Expression; Infertility, Male; Male; Mice; Mice, Transgenic; Rats; Recombinant Fusion Proteins; S Phase; Sexual Maturation; Spermatogenesis; Spermatozoa; Testis | 2003 |
[On the method of synthesis of the methyl ester of methoxyacetic acid].
Topics: Acetates; Esters | 1962 |
Sertoli cell modulates MAA-induced apoptosis of germ cells throughout voltage-operated calcium channels.
Topics: Acetates; Animals; Apoptosis; Calcium Channel Blockers; Calcium Channels; Cells, Cultured; Clusterin; Flow Cytometry; Germ Cells; Glycoproteins; Ion Channel Gating; Male; Molecular Chaperones; Rats; Seminiferous Epithelium; Sertoli Cells | 2004 |
Short-chain fatty acids enhance nuclear receptor activity through mitogen-activated protein kinase activation and histone deacetylase inhibition.
Topics: Acetates; Animals; Fatty Acids, Volatile; Gonadal Steroid Hormones; Histone Deacetylase Inhibitors; Immunosuppressive Agents; Mice; Mitogen-Activated Protein Kinases; Receptors, Cytoplasmic and Nuclear; Receptors, Progesterone; Signal Transduction; Xenobiotics | 2004 |
Evaluation of the protective effectiveness of gloves from occupational exposure to 2-methoxyethanol using the biomarkers of 2-methoxyacetic acid levels in the urine and plasma.
Topics: Acetates; Air Pollution, Indoor; Biomarkers; Environmental Monitoring; Ethylene Glycols; Gloves, Protective; Humans; Immunosuppressive Agents; Male; Manufactured Materials; Occupational Exposure; Semiconductors; Skin; Solvents; Teratogens | 2004 |
Determination of urinary metabolites of alkyl cellosolves by solid phase extraction and GC/FID.
Topics: Acetates; Chromatography, Gas; Ethylene Glycols; Flame Ionization; Humans; Particle Size | 2004 |
Modulation of MAA-induced apoptosis in male germ cells: role of Sertoli cell P/Q-type calcium channels.
Topics: Acetates; Animals; Apoptosis; Calcium Channel Blockers; Calcium Channels; Calcium Channels, P-Type; Calcium Channels, Q-Type; Cells, Cultured; Clusterin; Male; omega-Agatoxin IVA; Rats; Rats, Wistar; Seminiferous Tubules; Sertoli Cells; Spermatocytes; Spermatogenesis | 2005 |
Biotic and abiotic degradation behaviour of ethylene glycol monomethyl ether (EGME).
Topics: Acetaldehyde; Acetates; Acids; Aspergillus; Biodegradation, Environmental; Hydrogen-Ion Concentration; Iron; Organic Chemicals; Oxidation-Reduction; Polyethylene Glycols; Sodium Chloride; Sodium Hydroxide; Time Factors; Waste Disposal, Fluid; Water Supply | 2005 |
A teratoproteomics analysis: heat shock protein 70 is upregulated in mouse forelimb bud by methoxyacetic acid treatment.
Topics: Abnormalities, Drug-Induced; Acetates; Amino Acid Sequence; Animals; Blotting, Western; Electrophoresis, Gel, Two-Dimensional; Female; Forelimb; HSP70 Heat-Shock Proteins; Limb Deformities, Congenital; Male; Mice; Molecular Sequence Data; Pregnancy; Pregnancy, Animal; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Teratogens; Up-Regulation | 2005 |
Urinary methoxyacetic acid as an indicator of occupational exposure to ethylene glycol dimethyl ether.
Topics: Acetates; Air Pollutants, Occupational; Biomarkers; Electronics; Environmental Monitoring; Ethyl Ethers; Humans; Immunosuppressive Agents; Industry; Male; Occupational Exposure | 2005 |
Short-term oral toxicity of butyl ether, ethyl hexyl ether, methyl heptyl ether and 1,6-dimethoxyhexane in male rats and the role of 2-methoxyacetic acid.
Topics: Acetates; Administration, Oral; Animals; Biomarkers; Creatine; Creatinine; Dose-Response Relationship, Drug; Ethers; Ethyl Ethers; Gasoline; Hexanes; Male; Methyl Ethers; Organ Size; Organ Specificity; Oxidative Stress; Rats; Rats, Sprague-Dawley; Testis; Thymus Gland; Toxicity Tests | 2005 |
Testicular toxicity of candidate fuel additive 1,6-dimethoxyhexane: comparison with several similar aliphatic ethers.
Topics: Acetates; Animals; Apoptosis; Ethyl Ethers; Flow Cytometry; Gasoline; Hexanes; Male; Organ Size; Pachytene Stage; Rats; Rats, Sprague-Dawley; Seminiferous Tubules; Spermatogenesis; Structure-Activity Relationship; Testis; Thymus Gland | 2006 |
Gas chromatography analysis of urinary alkoxyacetic acids as biomarkers of exposure to aliphatic alkyl ethers.
Topics: Acetates; Animals; Biomarkers; Ethers; Flame Ionization; Gas Chromatography-Mass Spectrometry; Glycolates; Rats; Sensitivity and Specificity | 2006 |
Diethylene glycol monomethyl ether, ethylene glycol monomethyl ether and the metabolite, 2-methoxyacetic acid affect in vitro chondrogenesis.
Topics: Acetates; Animals; Apoptosis; Caspase 3; Caspase 9; Cell Proliferation; Cells, Cultured; Chick Embryo; Chondrogenesis; DNA Fragmentation; Dose-Response Relationship, Drug; Electrophoresis, Agar Gel; Ethylene Glycols; Limb Buds; Mitochondria; Polymerase Chain Reaction; Proteoglycans; Time Factors | 2006 |
Molecular basis for the enhanced lipase-catalyzed N-acylation of 1-phenylethanamine with methoxyacetate.
Topics: Acetates; Acylation; Catalysis; Hydrogen Bonding; Lipase; Models, Molecular; Molecular Structure; Phenethylamines; Phenylethyl Alcohol; Substrate Specificity | 2006 |
Correlation of appearance of metastasis-associated protein1 (Mta1) with spermatogenesis in developing mouse testis.
Topics: Acetates; Animals; Apoptosis; Blotting, Western; Immunohistochemistry; Male; Mice; Mice, Inbred BALB C; Pachytene Stage; Repressor Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Spermatocytes; Spermatogenesis; Testis; Trans-Activators; Transcription Factors | 2007 |
Correlation between urinary methoxyacetic acid and exposure of ethylene glycol dimethyl ether in a lithium battery plant.
Topics: Acetates; Ethyl Ethers; Ethylene Glycols; Female; Humans; Industry; Japan; Lithium; Male; Occupational Exposure | 2007 |
Chiral resolutions of (9-anthryl)methoxyacetic acid and (9-anthryl)hydroxyacetic acid by capillary electrophoresis.
Topics: Acetates; Electrophoresis, Capillary; Glycolates; Magnetic Resonance Spectroscopy; Stereoisomerism | 2008 |
Methoxyacetic acid-induced spermatocyte death is associated with histone hyperacetylation in rats.
Topics: Acetates; Acetylation; Animals; Cell Death; Gene Expression Profiling; Gene Expression Regulation; Histone Deacetylases; Histones; Immunosuppressive Agents; Male; Microarray Analysis; Rats; Rats, Sprague-Dawley; Spermatozoa; Testis | 2008 |
Interactions of methoxyacetic acid with androgen receptor.
Topics: Acetates; Animals; Cell Line; Endocrine Disruptors; Extracellular Signal-Regulated MAP Kinases; Gene Expression Profiling; Gene Expression Regulation; Humans; Leydig Cells; Male; Mice; Phosphatidylinositols; Receptors, Androgen; Signal Transduction; Testis; Transcriptional Activation | 2009 |
Differential expression of N-Myc downstream regulated gene 2 (NDRG2) in the rat testis during postnatal development.
Topics: Acetates; Age Factors; Animals; Apoptosis; Immunosuppressive Agents; Leydig Cells; Male; Nerve Tissue Proteins; Rats; Rats, Sprague-Dawley; Spermatogenesis; Testis | 2009 |
The short-chain fatty acid methoxyacetic acid disrupts endogenous estrogen receptor-alpha-mediated signaling.
Topics: Acetates; Animals; Cell Line, Tumor; Cytomegalovirus; Endocrine Disruptors; Estradiol; Estrogen Receptor alpha; Estrogen Receptor beta; Female; Gene Expression Regulation; HeLa Cells; Humans; Mice; Mice, Inbred C57BL; Promoter Regions, Genetic; Research Design; Signal Transduction; Uterus | 2009 |
Assignment of the structure of petrocortyne A by mixture syntheses of four candidate stereoisomers.
Topics: Acetates; Animals; Biological Products; Esters; Fatty Alcohols; Molecular Structure; Petrosia; Phenylacetates; Stereoisomerism | 2010 |
Impact of methoxyacetic acid on mouse Leydig cell gene expression.
Topics: Acetates; Animals; Cells, Cultured; Cluster Analysis; Cytotoxins; Gene Expression; Gene Expression Profiling; Leydig Cells; Male; Mice; Oligonucleotide Array Sequence Analysis; Response Elements; Validation Studies as Topic | 2010 |
Toxicant-induced leakage of germ cell-specific proteins from seminiferous tubules in the rat: relationship to blood-testis barrier integrity and prospects for biomonitoring.
Topics: Acetates; Animals; Biomarkers; Blood-Testis Barrier; Cadmium Chloride; Dinitrobenzenes; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Extracellular Fluid; Fatty Acid-Binding Proteins; Male; Rats; Rats, Wistar; Seminiferous Tubules; Sertoli Cells; Spermatozoa | 2010 |
Embryotoxicant-specific transcriptomic responses in rat postimplantation whole-embryo culture.
Topics: Abnormalities, Drug-Induced; Acetates; Animals; Caffeine; Embryo Culture Techniques; Embryo Implantation; Embryo, Mammalian; Embryonic Development; Gene Expression Profiling; Gene Expression Regulation, Developmental; Methylmercury Compounds; Oligonucleotide Array Sequence Analysis; Phthalic Acids; Rats; RNA, Messenger; Teratogens; Transcription, Genetic | 2010 |
Complex modulation of androgen responsive gene expression by methoxyacetic acid.
Topics: Acetates; Animals; Apoptosis; Cell Adhesion; Cell Line; Gene Expression Regulation; Ion Transport; Leydig Cells; Male; Mice; Phosphorylation; Receptors, Androgen; Testosterone | 2011 |
Ashwagandha leaf derived withanone protects normal human cells against the toxicity of methoxyacetic acid, a major industrial metabolite.
Topics: Acetates; Antioxidants; Cell Proliferation; Cellular Senescence; Cyclin-Dependent Kinase Inhibitor p16; Cyclin-Dependent Kinase Inhibitor p21; Cytoprotection; DNA Damage; Fibroblasts; Humans; Industry; Membrane Potential, Mitochondrial; Mitochondria; NF-E2-Related Factor 2; Plant Extracts; Plant Leaves; Reactive Oxygen Species; Response Elements; Retinoblastoma Protein; Signal Transduction; Triterpenes; Tumor Suppressor Protein p53; Withania; Withanolides | 2011 |
Chemical class-specific gene expression changes in the zebrafish embryo after exposure to glycol ether alkoxy acids and 1,2,4-triazole antifungals.
Topics: Acetates; Animal Testing Alternatives; Animals; Dose-Response Relationship, Drug; Embryo, Nonmammalian; Embryonic Development; Fungicides, Industrial; Gene Expression Profiling; Gene Expression Regulation, Developmental; Principal Component Analysis; Triazoles; Zebrafish | 2011 |
Hematological effects of exposure to mixtures of selected ethylene glycol alkyl ethers in rats.
Topics: Acetates; Alcohol Dehydrogenase; Aldehyde Dehydrogenase; Anemia, Hemolytic; Animals; Complex Mixtures; Dose-Response Relationship, Drug; Drug Tolerance; Erythrocyte Indices; Ethers; Ethylene Glycol; Ethylene Glycols; Hematologic Agents; Leukocytes; Male; Rats; Rats, Wistar | 2012 |
Expression of Rap1 during germ cell development in the rat and its functional implications in 2-methoxyacetic acid-induced spermatocyte apoptosis.
Topics: Acetates; Animals; Apoptosis; Germ Cells; Immunosuppressive Agents; Male; rap GTP-Binding Proteins; Rats; Rats, Sprague-Dawley; Spermatocytes; Testis | 2013 |
[Substance monograph for glycol ethers metabolized to methoxy acetic acid--reference and human biomonitoring (HBM) values for MAA in urine. Opinion of the Human Biomonitoring Commission of the German Federal Environment Agency (UBA)].
Topics: Acetates; Biological Assay; Environmental Monitoring; Environmental Pollutants; Ethylene Glycol; Germany; Guidelines as Topic; Humans; Urinalysis | 2014 |
Effects of ethylene glycol monomethyl ether and its metabolite, 2-methoxyacetic acid, on organogenesis stage mouse limbs in vitro.
Topics: Acetates; Animals; Apoptosis; Caspase 3; Cell Cycle Checkpoints; Cell Line, Tumor; Ethylene Glycols; Extremities; Histones; Mice; Organogenesis; RNA; Toxicity Tests | 2014 |
Development of a category approach to predict the testicular toxicity of chemical substances structurally related to ethylene glycol methyl ether.
Topics: Acetates; Animals; Databases, Factual; Ethylene Glycols; Male; Mice; Rats; Risk Assessment; Testis | 2014 |
Identification and quantification of acidosis inducing metabolites in cases of alcohols intoxication by GC-MS for emergency toxicology.
Topics: Acetates; Acidosis; Alcoholic Intoxication; Blood Chemical Analysis; Calibration; Chemistry Techniques, Analytical; Female; Formates; Gas Chromatography-Mass Spectrometry; Glycolates; Humans; Limit of Detection; Male; Reproducibility of Results; Toxicology; Urinalysis | 2015 |
Aminomethylphosphonic acid and methoxyacetic acid induce apoptosis in prostate cancer cells.
Topics: Acetates; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cell Cycle; Cell Line, Tumor; G1 Phase; Gene Expression Regulation, Neoplastic; Humans; Isoxazoles; Male; Organophosphonates; Prostate; Prostatic Neoplasms; Tetrazoles | 2015 |
Classification of reproductive toxicants with diverse mechanisms in the embryonic stem cell test.
Topics: 3T3 Cells; Acetates; Acetoacetates; Aminobutyrates; Animals; Benzhydryl Compounds; Benzimidazoles; Cadmium Chloride; Carbamates; Cells, Cultured; Embryonic Stem Cells; Mice; Oxazoles; Phenols; Sodium Chloride; Toxicity Tests | 2015 |
Use of a rat ex-vivo testis culture method to assess toxicity of select known male reproductive toxicants.
Topics: Acetates; Animals; Benzhydryl Compounds; Cells, Cultured; Dinitrobenzenes; Germ Cells; Hexachlorocyclohexane; Male; Phenols; Pilot Projects; Rats; Rats, Sprague-Dawley; Seminiferous Tubules; Sertoli Cells; Tissue Culture Techniques; Toxicity Tests | 2016 |
Mono-(2-ethylhexyl) phthalate-induced Sertoli cell injury stimulates the production of pro-inflammatory cytokines in Fischer 344 rats.
Topics: Acetates; Animals; Apoptosis; Cell Line; Cells, Cultured; Cytokines; Diethylhexyl Phthalate; Endocrine Disruptors; Macrophages; Male; Mice, Inbred C57BL; Rats, Inbred F344; RNA, Messenger; Sertoli Cells; Species Specificity | 2017 |
Prenatal exposure to glycol ethers and cryptorchidism and hypospadias: a nested case-control study.
Topics: Acetates; Adult; Case-Control Studies; Cohort Studies; Cryptorchidism; Endocrine Disruptors; Ethers; Female; Glycols; Hazardous Substances; Humans; Hypospadias; Logistic Models; Male; Maternal Exposure; Occupational Exposure; Odds Ratio; Pregnancy; Prenatal Exposure Delayed Effects; Risk Factors; Solvents; Young Adult | 2018 |
Prenatal exposure to glycol ethers and motor inhibition function evaluated by functional MRI at the age of 10 to 12 years in the PELAGIE mother-child cohort.
Topics: Acetates; Adult; Brain; Child; Cohort Studies; Environmental Pollutants; Ethers; Female; France; Glycols; Humans; Magnetic Resonance Imaging; Male; Maternal Exposure; Motor Activity; Pregnancy; Prenatal Exposure Delayed Effects; Solvents | 2019 |
Methoxyacetic acid esters: Applications in protecting group and glycosylation chemistry.
Topics: Acetates; Esters; Glycosylation; Stereoisomerism | 2019 |
The urinary metabolic profile of diethylene glycol methyl ether and triethylene glycol methyl ether in Sprague-Dawley rats and the role of the metabolite methoxyacetic acid in their toxicity.
Topics: Acetates; Administration, Oral; Animals; Ethylene Glycols; Male; Methyl Ethers; Rats, Sprague-Dawley; Solvents | 2020 |
Methoxyacetic acid inhibits histone deacetylase and impairs axial elongation morphogenesis of mouse gastruloids in a retinoic acid signaling-dependent manner.
Topics: Acetates; Animals; Gastrulation; Histone Deacetylases; Mice; Tretinoin | 2020 |
A comparative study of the effects of 3 testicular toxicants in cultures of seminiferous tubules of rats or of domestic cats (veterinary waste): An alternative method for reprotoxicology.
Topics: Acetates; Animals; Benzimidazoles; Carbamates; Cats; Dinitrobenzenes; Male; Rats; Seminiferous Tubules; Sertoli Cells; Spermatogenesis; Testis | 2022 |