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methotrimeprazine and morphine

methotrimeprazine has been researched along with morphine in 35 studies

Research

Studies (35)

TimeframeStudies, this research(%)All Research%
pre-199027 (77.14)18.7374
1990's1 (2.86)18.2507
2000's3 (8.57)29.6817
2010's4 (11.43)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY1
Lombardo, F; Obach, RS; Waters, NJ1
Bellman, K; Knegtel, RM; Settimo, L1
Born, CK; St John, AB1
Kuromi, H; Satoh, M; Takagi, H1
Bantutova, I; Iakimova, K; Koleva, E; Ovcharova, R1
Hoffmeister, F1
Winter, CA1
Hálek, J; Jezdinský, J1
Kuromi, H; Sato, M; Takagi, H2
Bass, P; Kennedy, JA; Wiley, JN1
Vandam, LD1
Kocher, R; Rohrer, G1
Domino, EF; Wilson, AE1
Abe, T; Kaneko, T; Takagi, H1
Lasagna, L2
Kast, EC1
Gray, WD; Osterberg, AC; Scuto, TJ1
Evers, JL; Hobika, GH; Moore, RH; Mostert, JW; Murphy, GP1
Sulman, FG; Weller, CP2
Petts, HV; Pleuvry, BJ1
Herlitz, J; Karlson, BW; Sjölin, M1
MAXWELL, DR; PALMER, HT; RYALL, RW1
DE CASTRO, J; MUNDELEER, P1
BERNIER, J; BLOOMFIELD, S; SIMARD SAVOIE, S; TETREAULT, L1
BERNIER, J; BLOOMFIELD, S; SIMARD-SAVOIE, S; TETREAULT, L1
BELANGER, G; GAGNON, R; POIRIER, L; TETREAULT, L1
Al-Tannak, NF; Cable, CG; McArthur, DA; Watson, DG1
Ayestarán, A; Calpena, AC; Fernandez-Campos, F; Lacasa, C; Mallandrich, M1
Kaminska, E; Leppert, W; Mikolajczak, P; Okulicz-Kozaryn, I; Szulc, M1

Reviews

2 review(s) available for methotrimeprazine and morphine

ArticleYear
Drug therapy: analgetic drugs--the potent analgetics.
    The New England journal of medicine, 1972, Feb-03, Volume: 286, Issue:5

    Topics: Analgesics; Blood Circulation; Fentanyl; Humans; Intestines; Levallorphan; Meperidine; Methadone; Methotrimeprazine; Morphinans; Morphine; Nalorphine; Narcotic Antagonists; Nausea; Pain; Pentazocine; Psychopharmacology; Respiration; Substance-Related Disorders; Urinary Tract; Vomiting

1972
THE CLINICAL EVALUATION OF MORPHINE AND ITS SUBSTITUTES AS ANALGESICS.
    Pharmacological reviews, 1964, Volume: 16

    Topics: Analgesics; Analgesics, Non-Narcotic; Antipyretics; Biomedical Research; Codeine; Cyclazocine; Dextromoramide; Dextropropoxyphene; Heroin; Humans; Hydromorphone; Isonipecotic Acids; Meperidine; Methadone; Methotrimeprazine; Morphine; Nalorphine; Narcotic Antagonists; Oxymorphone; Pentazocine; Phenazocine; Substance-Related Disorders; Toxicology

1964

Trials

4 trial(s) available for methotrimeprazine and morphine

ArticleYear
[Treatment of severe chronic pains with a combination of thymoleptics and neuroleptics (author's transl)].
    Schweizerische Rundschau fur Medizin Praxis = Revue suisse de medecine Praxis, 1974, Dec-31, Volume: 63, Issue:52

    Topics: Adult; Antidepressive Agents; Atropine; Chlorpromazine; Clinical Trials as Topic; Clomipramine; Drug Combinations; Female; Haloperidol; Humans; Imipramine; Male; Methotrimeprazine; Middle Aged; Morphine; Neoplasms; Pain; Papaverine; Tranquilizing Agents

1974
Drug interaction in the field of analgesic drugs.
    Proceedings of the Royal Society of Medicine, 1965, Volume: 58, Issue:11 Part 2

    Topics: Analgesics; Aspirin; Caffeine; Clinical Trials as Topic; Cyclazocine; Drug Synergism; Humans; Meperidine; Methotrimeprazine; Morphine; Nalorphine; Narcotic Antagonists; Pentazocine; Phenacetin; Placebos; Tranquilizing Agents; Triflupromazine

1965
An understanding of pain and its measurement.
    Medical times, 1966, Volume: 94, Issue:12

    Topics: Clinical Trials as Topic; Humans; Methotrimeprazine; Morphine; Pain

1966
Interactions of morphine and methotrimeprazine in mouse and man with respect to analgesia, respiration and sedation.
    British journal of anaesthesia, 1983, Volume: 55, Issue:5

    Topics: Adult; Analgesia; Animals; Drug Synergism; Female; Humans; Hypnotics and Sedatives; Male; Methotrimeprazine; Mice; Morphine; Motor Activity; Pain; Reaction Time; Respiration; Sensory Thresholds

1983

Other Studies

29 other study(ies) available for methotrimeprazine and morphine

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
    Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5

    Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution

2004
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
    Pharmaceutical research, 2014, Volume: 31, Issue:4

    Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation

2014
Characterization of analgesic and activity effects of methotrimeprazine and morphine.
    Research communications in chemical pathology and pharmacology, 1979, Volume: 26, Issue:1

    Topics: Analgesics; Animals; Binding, Competitive; Male; Methotrimeprazine; Mice; Mice, Inbred ICR; Morphine; Motor Activity; Naloxone

1979
Inhibition of thalamic and hypothalamic somatosensory evoked potentials by stimulation of substantia nigra and its modification by morphine and methotrimeprazine (levomepromazine).
    Japanese journal of pharmacology, 1976, Volume: 26, Issue:3

    Topics: Animals; Electric Stimulation; Evoked Potentials; Female; Hypothalamus; Male; Methotrimeprazine; Morphine; Rabbits; Sciatic Nerve; Substantia Nigra; Thalamus; Time Factors

1976
[Effect on morphine hyperthermia of dopaminergic agents].
    Eksperimentalna meditsina i morfologiia, 1985, Volume: 24, Issue:4

    Topics: Animals; Apomorphine; Body Temperature; Bromocriptine; Drug Interactions; Fever; Haloperidol; Male; Methotrimeprazine; Morphine; Naloxone; Rats; Rats, Inbred Strains; Rectum; Time Factors

1985
[On the influence of analgesics on the "writhing" withdrawal symptom in rats].
    Naunyn-Schmiedebergs Archiv fur experimentelle Pathologie und Pharmakologie, 1968, Volume: 260, Issue:2

    Topics: Depression, Chemical; Dextropropoxyphene; Humans; Methotrimeprazine; Morphine; Pain; Phenacetin; Pyrazoles; Quinones; Spasm; Substance Withdrawal Syndrome; Sulfonic Acids

1968
Pharmacological properties related to the mechanism of action of potent analgesic drugs.
    Pure and applied chemistry. Chimie pure et appliquee, 1969, Volume: 19, Issue:1

    Topics: Analgesics; Animals; Benzimidazoles; Cyclazocine; Humans; Isonipecotic Acids; Methotrimeprazine; Mice; Morphinans; Morphine; Nalorphine; Pentazocine; Rabbits; Rats

1969
The effects of some analgesics and neuroleptics upon the reflexive and affective components of the formaldehyde- and bradykinin-induced nociceptive reactions in rats.
    Activitas nervosa superior, 1974, Volume: 16, Issue:3

    Topics: Aminopyrine; Analgesics; Animals; Behavior, Animal; Bradykinin; Chlorpromazine; Dose-Response Relationship, Drug; Emotions; Formaldehyde; Methotrimeprazine; Morphine; Pain; Rats; Rats, Inbred Strains; Reflex

1974
Central actions of methotrimeprazine (levomepromazine) as an analgesic. 1. Depressant action on EEG arousal response induced by different sensory stimulations.
    Japanese journal of pharmacology, 1972, Volume: 22, Issue:2

    Topics: Acoustic Stimulation; Analgesics; Animals; Arousal; Brain; Chlorpromazine; Dental Pulp; Electric Stimulation; Electroencephalography; Female; Hippocampus; Male; Methotrimeprazine; Morphine; Motor Cortex; Physical Stimulation; Rabbits; Sciatic Nerve; Somatosensory Cortex

1972
Measurement of fecal output in rats.
    The American journal of digestive diseases, 1972, Volume: 17, Issue:10

    Topics: 5-Hydroxytryptophan; Amphetamine; Animals; Apomorphine; Atropine; Chlorpromazine; Codeine; Cyclazocine; Digestive System; Feces; Housing, Animal; Levallorphan; Magnesium Sulfate; Male; Mecamylamine; Meperidine; Methotrimeprazine; Methylamines; Mineral Oil; Morphine; Muscle, Smooth; Opium; Papaverine; Pentazocine; Rats

1972
Effects of morphine and methotrimeprazine (levomepromazine) on the caudate-induced inhibition of the thalamic somatosensory evoked potential.
    European journal of pharmacology, 1973, Volume: 24, Issue:3

    Topics: Anesthesia; Animals; Caudate Nucleus; Conditioning, Psychological; Electrodes; Evoked Potentials; Methotrimeprazine; Morphine; Nalorphine; Rabbits; Thalamus; Time Factors

1973
Psychotropic drug influences on brain acetylcholine utilization.
    Psychopharmacologia, 1972, Volume: 25, Issue:4

    Topics: Acetylcholine; Animals; Antidepressive Agents; Brain; Chlordiazepoxide; Chlorpromazine; Dextroamphetamine; Hemicholinium 3; Imipramine; Lysergic Acid Diethylamide; Male; Methotrimeprazine; Morphine; Pentobarbital; Phencyclidine; Rats; Rats, Inbred Strains; Scopolamine; Tranquilizing Agents

1972
[Assessment of analgesic actions of narcotic antagonists, with special reference to nociception induced by retrograde injection of bradykinin into the carotid artery of rats].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1971, Volume: 67, Issue:1

    Topics: Acetates; Aminopyrine; Analgesics; Animals; Aspirin; Bradykinin; Carotid Arteries; Chlorpromazine; Codeine; Indomethacin; Injections, Intra-Arterial; Levallorphan; Male; Methods; Methotrimeprazine; Mice; Morphine; Nalorphine; Narcotic Antagonists; Pain; Pentazocine

1971
Measurement of the analgesic efficacy and potency of pentazocine by the D'Amour and Smith method.
    The Journal of pharmacology and experimental therapeutics, 1970, Volume: 172, Issue:1

    Topics: Analgesics; Animals; Chlorpromazine; Chlorzoxazone; Cyclazocine; Hot Temperature; Male; Meperidine; Methods; Methotrimeprazine; Morphinans; Morphine; Nalorphine; Narcotic Antagonists; Pentazocine; Phenobarbital; Rats; Reaction Time

1970
Circulatory effects of analgesic and neuroleptic drugs in patients with chronic renal failure undergoing maintenance dialysis.
    British journal of anaesthesia, 1970, Volume: 42, Issue:6

    Topics: Analgesics; Benperidol; Blood Circulation; Blood Pressure; Cardiac Output; Fentanyl; Heart Rate; Humans; Kidney Failure, Chronic; Meperidine; Methotrimeprazine; Morphine; Oxygen; Pentazocine; Pulmonary Edema; Renal Dialysis

1970
Drug action on tail shock-induced vocalization in mice and its relevance to analgesia.
    European journal of pharmacology, 1970, Volume: 9, Issue:2

    Topics: Analgesia; Animals; Cerebral Cortex; Chlorpromazine; Codeine; Cyclazocine; Electric Stimulation; Hydroxyzine; Levallorphan; Male; Methadone; Methotrimeprazine; Mice; Morphinans; Morphine; Nalorphine; Narcotic Antagonists; Narcotics; Pentazocine; Tail; Tranquilizing Agents; Vocalization, Animal

1970
Activity of major analgesics on motor nociceptive responses in decerebrate mice.
    Psychopharmacologia, 1971, Volume: 20, Issue:3

    Topics: Animals; Decerebrate State; Male; Methotrimeprazine; Mice; Morphine; Motor Neurons; Neural Conduction; Pain; Pentazocine; Perception; Reaction Time

1971
Methotrimeprazine (Levoprome)--a potent analgesic.
    The Medical letter on drugs and therapeutics, 1967, Jun-30, Volume: 9, Issue:13

    Topics: Humans; Meperidine; Methotrimeprazine; Morphine; Pain; Preanesthetic Medication

1967
Clinical factors associated with pain in acute myocardial infarction.
    Cardiology, 1993, Volume: 83, Issue:1-2

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Ambulances; Angina Pectoris; Dose-Response Relationship, Drug; Drug Therapy, Combination; Electrocardiography; Female; Humans; Infusions, Intravenous; Male; Methotrimeprazine; Middle Aged; Morphine; Myocardial Infarction; Nitroglycerin; Pain Measurement

1993
A comparison of the analgesic and some other central properties of methotrimeprazine and morphine.
    Archives internationales de pharmacodynamie et de therapie, 1961, Jun-01, Volume: 132

    Topics: Analgesics; Analgesics, Non-Narcotic; Antipyretics; Central Nervous System; Methotrimeprazine; Morphine; Nervous System; Phenothiazines

1961
[Practice of neuroleptanalgesia. (General remarks, technics and schemas)].
    Agressologie: revue internationale de physio-biologie et de pharmacologie appliquees aux effets de l'agression, 1962, Volume: 3(Special)

    Topics: Analgesics; Analgesics, Non-Narcotic; Antipyretics; Chlorpromazine; Dextromoramide; Haloperidol; Methotrimeprazine; Morphine; Neuroleptanalgesia; Preanesthetic Medication

1962
[CLINICAL EVALUATION OF THE ANALGESIC PROPERTIES OF LEVOMEPROMAZINE, MORPHINE AND A PLACEBO ON CHRONIC PAIN].
    L'union medicale du Canada, 1964, Volume: 93

    Topics: Analgesia; Analgesics; Chronic Pain; Humans; Methotrimeprazine; Morphine; Pain; Pain Management; Placebos

1964
COMPARATIVE ANALGESIC ACTIVITY OF LEVOMEPROMAZINE AND MORPHINE IN PATIENTS WITH CHRONIC PAIN.
    Canadian Medical Association journal, 1964, May-16, Volume: 90

    Topics: Analgesics; Analgesics, Non-Narcotic; Antipyretics; Biomedical Research; Chronic Disease; Chronic Pain; Cross-Over Studies; Double-Blind Method; Geriatrics; Humans; Methotrimeprazine; Morphine; Pain; Placebos; Toxicology

1964
[COMPARATIVE STUDY OF EXPERIMENTAL ANALGESIC PROPERTIES OF LEVOMEPROMAZINE IN THE MONKEY].
    Revue canadienne de biologie, 1964, Volume: 23

    Topics: Analgesia; Analgesics; Animals; Brain; Dental Pulp; Electrocoagulation; Electrophysiology; Haplorhini; Mesencephalon; Methotrimeprazine; Morphine; Pain; Pharmacology; Placebos; Research

1964
A stability indicating assay for a combination of morphine sulphate with levomepromazine hydrochloride used in palliative care.
    Journal of clinical pharmacy and therapeutics, 2012, Volume: 37, Issue:1

    Topics: Analgesics, Non-Narcotic; Analgesics, Opioid; Chromatography, High Pressure Liquid; Drug Combinations; Drug Stability; Drug Storage; Humans; Injections; Light; Methotrimeprazine; Morphine; Palliative Care; Sulfoxides; Temperature

2012
Stability studies of binary and ternary mixtures containing morphine, midazolam, levomepromazine and hyoscine butylbromide for parenteral administration.
    The Journal of pharmacy and pharmacology, 2013, Volume: 65, Issue:3

    Topics: Butylscopolammonium Bromide; Drug Combinations; Drug Stability; Drug Storage; Infusions, Parenteral; Methotrimeprazine; Midazolam; Morphine; Palliative Care

2013
Analgesic effects of morphine in combination with adjuvant drugs in rats.
    Pharmacology, 2014, Volume: 94, Issue:5-6

    Topics: Adjuvants, Pharmaceutic; Analgesics, Opioid; Animals; Butylscopolammonium Bromide; Drug Interactions; Drug Therapy, Combination; Haloperidol; Male; Methotrimeprazine; Metoclopramide; Midazolam; Morphine; Pain; Rats, Wistar

2014