methotrimeprazine has been researched along with clozapine in 21 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (4.76) | 18.2507 |
| 2000's | 7 (33.33) | 29.6817 |
| 2010's | 9 (42.86) | 24.3611 |
| 2020's | 4 (19.05) | 2.80 |
| Authors | Studies |
|---|---|
| Topliss, JG; Yoshida, F | 1 |
| Gao, F; Lombardo, F; Shalaeva, MY; Tupper, KA | 1 |
| Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
| Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
| Bellman, K; Knegtel, RM; Settimo, L | 1 |
| Jadhav, A; Kerns, E; Nguyen, K; Shah, P; Sun, H; Xu, X; Yan, Z; Yu, KR | 1 |
| Kabir, M; Kerns, E; Nguyen, K; Shah, P; Sun, H; Wang, Y; Xu, X; Yu, KR | 1 |
| Kabir, M; Kerns, E; Neyra, J; Nguyen, K; Nguyễn, ÐT; Shah, P; Siramshetty, VB; Southall, N; Williams, J; Xu, X; Yu, KR | 1 |
| Cecyre, D; Lal, S; Nair, NP; Quirion, R | 1 |
| Baeza, I; Bernardo, M; Lázaro, ML; Mané, A; Morer, A | 1 |
| Boncompagni, G; Bugamelli, F; Franchini, L; Kenndler, E; Mercolini, L; Raggi, MA | 1 |
| Bartoletti, C; Boncompagni, G; Bugamelli, F; Kenndler, E; Mandrioli, R; Raggi, MA | 1 |
| Bramness, JG; Gjerden, P; Slørdal, L | 1 |
| Bitter, I; Gazdag, G; Tolna, J | 1 |
| Blondon, H; Bulot, V; Lemogne, C; Nebot, N; Roux, P | 1 |
| Sakamoto, S; Sato, K; Takaki, M; Yamada, N; Yoshimura, B | 1 |
| Basińska-Ziobroń, A; Danek, PJ; Daniel, WA; Wójcikowski, J | 1 |
| Abe, Y; Hamamatsu, S; Hattori, Y; Ikegami, Y; Iwata, N; Matsuo, K; Matsuoka, Y; Obara, K; Shioda, N; Tanaka, Y; Yamaki, F; Yoshio, T; Yoshioka, K | 1 |
| Araujo, ARTS; Barroso, M; Gallardo, E; Gameiro, C; Gonçalves, J; Passarinha, LA; Rosado, T; Soares, S | 1 |
1 review(s) available for methotrimeprazine and clozapine
| Article | Year |
|---|---|
[Antipsychotic drug combinations in the treatment of schizophrenia. A review of the literature].
Topics: Antipsychotic Agents; Clozapine; Drug Therapy, Combination; Haloperidol; Humans; Methotrimeprazine; Randomized Controlled Trials as Topic; Schizophrenia; Treatment Outcome | 2012 |
20 other study(ies) available for methotrimeprazine and clozapine
| Article | Year |
|---|---|
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
ElogD(oct): a tool for lipophilicity determination in drug discovery. 2. Basic and neutral compounds.
Topics: 1-Octanol; Chromatography, High Pressure Liquid; Pharmaceutical Preparations; Solubility; Water | 2001 |
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution | 2004 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation | 2014 |
Highly predictive and interpretable models for PAMPA permeability.
Topics: Artificial Intelligence; Caco-2 Cells; Cell Membrane Permeability; Humans; Models, Biological; Organic Chemicals; Regression Analysis; Support Vector Machine | 2017 |
Predictive models of aqueous solubility of organic compounds built on A large dataset of high integrity.
Topics: Drug Discovery; Organic Chemicals; Pharmaceutical Preparations; Solubility | 2019 |
Retrospective assessment of rat liver microsomal stability at NCATS: data and QSAR models.
Topics: Animals; Computer Simulation; Databases, Factual; Drug Discovery; High-Throughput Screening Assays; Liver; Machine Learning; Male; Microsomes, Liver; National Center for Advancing Translational Sciences (U.S.); Pharmaceutical Preparations; Quantitative Structure-Activity Relationship; Rats; Rats, Sprague-Dawley; Retrospective Studies; United States | 2020 |
Levomepromazine receptor binding profile in human brain--implications for treatment-resistant schizophrenia.
Topics: Adolescent; Aged; Binding, Competitive; Brain; Chlorpromazine; Clozapine; Corpus Striatum; Culture Techniques; Female; Frontal Lobe; Humans; Male; Methotrimeprazine; Receptors, Dopamine; Receptors, Neurotransmitter; Schizophrenia; Schizophrenic Psychology; Synaptic Membranes | 1993 |
Neuroleptic malignant syndrome associated with risperidone in a male with early-onset schizophrenia.
Topics: Administration, Oral; Adolescent; Antipsychotic Agents; Clozapine; Combined Modality Therapy; Electroconvulsive Therapy; Humans; Injections, Intramuscular; Male; Methotrimeprazine; Neuroleptic Malignant Syndrome; Recurrence; Risperidone; Schizophrenia | 2005 |
Simultaneous determination of the antipsychotic drugs levomepromazine and clozapine and their main metabolites in human plasma by a HPLC-UV method with solid-phase extraction.
Topics: Antipsychotic Agents; Calibration; Chromatography, High Pressure Liquid; Clozapine; Humans; Methotrimeprazine; Reference Standards; Reproducibility of Results; Sensitivity and Specificity; Spectrophotometry, Ultraviolet | 2007 |
Possible levomepromazine-clozapine interaction: two case reports.
Topics: Adolescent; Antipsychotic Agents; Clozapine; Drug Interactions; Humans; Male; Mental Disorders; Methotrimeprazine; Middle Aged | 2007 |
Prescription persistence and safety of antipsychotic medication: a national registry-based 3-year follow-up.
Topics: Adult; Aged; Antiparkinson Agents; Antipsychotic Agents; Chlorprothixene; Cholinergic Antagonists; Clopenthixol; Clozapine; Drug Prescriptions; Female; Follow-Up Studies; Haloperidol; Humans; Logistic Models; Male; Methotrimeprazine; Middle Aged; Mortality; Norway; Odds Ratio; Piperazines; Registries; Thiazoles | 2010 |
Systematic prevention of severe constipation induced by antipsychotic agents: A quasi-experimental study.
Topics: Administration, Rectal; Antipsychotic Agents; Clopenthixol; Clozapine; Constipation; Drug Administration Schedule; Drug Monitoring; Drug Therapy, Combination; Humans; Intensive Care Units; Laxatives; Methotrimeprazine; Plant Gums; Polyethylene Glycols; Severity of Illness Index; Sterculia; Surface-Active Agents | 2016 |
Predictors of remission during acute treatment of first-episode schizophrenia patients involuntarily hospitalized and treated with algorithm-based pharmacotherapy: Secondary analysis of an observational study.
Topics: Administration, Oral; Adult; Algorithms; Antipsychotic Agents; Clozapine; Commitment of Mentally Ill; Drug Therapy, Combination; Female; Haloperidol; Humans; Injections, Intramuscular; Male; Methotrimeprazine; Olanzapine; Psychotic Disorders; Quetiapine Fumarate; Retrospective Studies; Risperidone; Schizophrenia; Schizophrenic Psychology; Treatment Failure; Treatment Outcome | 2019 |
Levomepromazine and clozapine induce the main human cytochrome P450 drug metabolizing enzyme CYP3A4.
Topics: Antipsychotic Agents; Cells, Cultured; Clozapine; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Enzyme Induction; Hepatocytes; Humans; Liver; Methotrimeprazine; RNA, Messenger | 2021 |
Inhibitory Effects of Antipsychotics on the Contractile Response to Acetylcholine in Rat Urinary Bladder Smooth Muscles.
Topics: Acetylcholine; Aging; Animals; Antipsychotic Agents; Chlorpromazine; Cholinergic Antagonists; Clozapine; Dibenzothiepins; Male; Mental Disorders; Methotrimeprazine; Muscle Contraction; Muscle, Smooth; Olanzapine; Quetiapine Fumarate; Rats, Wistar; Urinary Bladder; Urologic Diseases | 2021 |
Evaluation of Antipsychotic Drugs' Stability in Oral Fluid Samples.
Topics: Antipsychotic Agents; Chlorpromazine; Clozapine; Gas Chromatography-Mass Spectrometry; Haloperidol; Methotrimeprazine; Quetiapine Fumarate | 2023 |