methoctramine has been researched along with piperidines in 127 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (3.94) | 18.7374 |
| 1990's | 62 (48.82) | 18.2507 |
| 2000's | 48 (37.80) | 29.6817 |
| 2010's | 12 (9.45) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sastry, BV; Stephan, CC | 1 |
| Hey, C; Racké, K; Wessler, I | 1 |
| Martin, JR | 1 |
| Blazynski, C; McIntosh, H | 1 |
| Anderson, DJ; Connolly, T; McKinney, M; Miller, JH; Vella-Rountree, L | 1 |
| Jaiswal, N; Lambrecht, G; Malik, KU; Mutschler, E; Tacke, R | 1 |
| Angeli, P; Brasili, L; Cingolani, ML; Marucci, G; Pigini, P; Tonnini, MC | 1 |
| Costa, G; Massi, M; Melchiorre, C; Perfumi, M; Polidori, C; Sajia, A | 1 |
| Jaiswal, N; Malik, KU | 1 |
| Angeli, P; Bianchi, S; Imeri, L; Mancia, M | 3 |
| Yang, CM | 1 |
| Bast, A; Doelman, CJ; Nagtegaal, JE; Rodrigues de Miranda, JF; Sprong, RC | 1 |
| Massi, M; Melchiorre, C; Perfumi, M; Polidori, C; Pompei, PL | 1 |
| Duckles, SP; Ehlert, FJ; Garcia-Villalon, AL; Krause, DN | 1 |
| Michel, AD; Whiting, RL | 1 |
| Barnes, PJ; Mak, JC | 1 |
| Alonso, R; Didier, M; Soubrie, P | 1 |
| el-Fakahany, EE; Lee, NH | 1 |
| Camus, J; Christophe, J; Tastenoy, M; Waelbroeck, M | 1 |
| Anderson, D; el-Fakahany, EE; Forray, C; McKinney, M | 1 |
| Boddeke, H; Christophe, J; Feifel, R; Lambrecht, G; Mutschler, E; Strohmann, C; Tacke, R; Waelbroeck, M; Wagner-Röder, M; Zilch, H | 1 |
| Field, JL; Newberry, NR | 1 |
| Dainty, IA; Dubuque, LK; Eglen, RM; Montgomery, WW; Whiting, RL | 1 |
| Barnes, PJ; Mak, JC; McCormack, DG; Minette, P | 1 |
| Hackmiller, RC; Jumblatt, JE | 1 |
| Imaizumi, Y; Kawai, T; Masuda, Y; Ryang, S; Tanaka, M; Watanabe, M; Yamahara, NS | 1 |
| Eglen, RM; Reddy, H; Watson, N | 1 |
| Boselli, C; Grana, E | 1 |
| Nakamura, K; Okuma, Y; Osumi, Y; Yokotani, K | 1 |
| Howell, RE; Kovalsky, MP | 1 |
| Imaizumi, Y; Tanaka, M; Watanabe, M; Yamahara, NS | 1 |
| Hamstra, JJ; Roffel, AF; Santing, RE; ten Berge, RE; Zaagsma, J | 1 |
| Ballabeni, V; Barocelli, E; Caretta, A; Chiavarini, M; Impicciatore, M; Molina, E | 1 |
| Howell, RE; Kovalsky, MP; Laemont, KD | 1 |
| Ko, FN; Lin, CH; Teng, CM; Wu, YC; Yang, CM | 1 |
| Bissonnette, BM; Brasitus, TA; Khare, S; Sitrin, MD; Tien, XY; Wali, RK; Wilson, D | 1 |
| Abysique, A; Blanquet, F; Gonella, J | 1 |
| Eglen, RM; Watson, N | 1 |
| Davenport, TA; Fukumoto, Y; Gousse, A; Kamai, T; Latifpour, J; Weiss, RM; Yoshida, M | 1 |
| Fukomoto, Y; Latifpour, J; Weiss, RM; Yoshida, M | 1 |
| Eglen, RM; Harris, GC | 1 |
| Osumi, Y; Yokotani, K | 1 |
| Sjögren, C; Tobin, G | 1 |
| Asano, T; Ito, S; Nakazato, Y; Ohta, T; Otsuguro, K | 1 |
| Haddad, EB; Khawaja, AM; Mak, JC; Ramnarine, SI; Rogers, DF | 1 |
| Acs, Z; Makara, GB; Pintér, I | 1 |
| Janković, SM; Milovanović, DR | 1 |
| Cheng, JT; Hung, YC; Lin, SN; Tong, YC | 1 |
| Levin, RJ; Przyborski, SA | 1 |
| Semba, K; White, TD | 1 |
| Hoover, DB; Neely, DA | 1 |
| Baba, H; Goldstein, PA; Kohno, T; Okamoto, M; Shimoji, K; Yoshimura, M | 1 |
| Cobuzzi, A; Lai, FM; Spinelli, W | 1 |
| Amenta, F; Tayebati, SK; Vitaioli, L; Zaccheo, D | 1 |
| Brefel-Courbon, C; Freslon, JL; Lazartigues, E; Montastruc, JL; Pelat, M; Rascol, O; Tellioglu, T; Tran, MA | 1 |
| Inadome, A; Kawano, T; Miyamoto, Y; Seshita, H; Takahashi, W; Ueda, S; Yono, M; Yoshida, M | 1 |
| Braverman, A; Legos, J; Luthin, G; Ruggieri, M; Young, W | 1 |
| Budriesi, R; Chiarini, A; Melchiorre, C; Minarini, A; Spampinato, S; Tumiatti, V | 1 |
| Haapalinna, A; Larson, J; Niittykoski, M; Ruotsalainen, S; Sirviö, J | 1 |
| Pagano, AP; Parkman, HP; Ryan, JP | 1 |
| Bernardi, G; Bonci, A; Grillner, P; Mercuri, NB; Svensson, TH | 1 |
| Capasso, F; Di Carlo, G; Izzo, AA; Mascolo, N | 1 |
| Goldie, RG; Preuss, JM | 1 |
| Baghdoyan, HA; Lydic, R | 1 |
| Grbović, L; Jovanović, A; Pesić, S; Radenković, M | 1 |
| Halayko, AJ; Kahraman, S; Mitchell, RW; Solway, J; Wylam, ME | 1 |
| Levendusky, M; Longhurst, PA | 1 |
| Bourreau, JP; Huang, Y; Shen, S | 1 |
| Krysiak, PS; Laurier, LG; Preiksaitis, HG; Sims, SM; Wang, J | 1 |
| Chapple, CR; Chess-Williams, R; Yamanishi, T; Yasuda, K | 2 |
| Daniels, DV; Eglen, RM; Ford, AP; Hegde, SS; Meloy, TD | 1 |
| Dohi, S; Ishizawa, Y; Ma, HC; Wang, YF; Yanagidate, F | 1 |
| Kadota, H; Kuwahara, M; Mikami, H; Nishibata, R; Tsubone, H | 1 |
| Choppin, A; Eglen, RM | 1 |
| Herzog, M; Liu, J; Scherer, EQ; Scofield, MA; Shimozono, M; Wangemann, P | 1 |
| Avellar, MC; Guaze, EF; Maróstica, E; Porto, CS | 1 |
| Grbović, L; Jovanović, A; Pesić, S | 2 |
| Delbro, DS; Giglio, D; Tobin, G | 2 |
| Abdel-Wahab, YH; Flatt, PR; Mathias, PC; Miguel, JC | 1 |
| Giglio, D; Götrick, B; Tobin, G | 1 |
| Emala, CW; Hirshman, CA; Jooste, E; Klafter, F | 1 |
| Abe, K; Chikuma, T; Hojyo, H; Kato, M; Miyatake, T; Taguchi, K; Utsunomiya, I | 1 |
| Benavides-Haro, DE; Navarro-Polanco, RA; Sánchez-Chapula, JA | 1 |
| Jankovic, SM; Jankovic, SV; Protic, BA | 2 |
| Aita, T; Ishihata, A; Katano, Y; Tezuka, A | 1 |
| Callaghan, B; Keef, KD; Koh, SD | 1 |
| Dagaev, SG; Dolgo-Saburov, VB; Fil'ko, OA; Glukhova, RI; Khrabrova, AV; Kubarskaya, LG; Mukovskii, LA; Sanotskii, VI | 1 |
| Ando, S; Harasawa, I; Honda, K; Kamiya, HO; Koga, K; Takano, Y | 1 |
| Izumi, Y; Komori, S; Matsuyama, H; Okamoto, H; Sakamoto, T; Uchiyama, M; Unno, T; Wess, J; Yamada, M | 1 |
| Boselli, E; Chassard, D; Duflo, F; Ryvlin, P | 1 |
| Gobbi, MD; Hita, FJ; Pujol Lereis, VA; Rodriguez, MC; Rothlin, RP; Verdi, MG | 1 |
| Hattori, M; Komori, S; Matsuyama, H; Nishimura, M; Sakamoto, T; Uchiyama, M; Unno, T | 1 |
| de Groat, WC; Ng, YK; Wu, HY | 1 |
| Chapple, CR; Chess-Williams, R; Stevens, LA | 1 |
| Aronsson, P; Eriksson, L; Giglio, D; Tobin, G | 1 |
| Jurkiewicz, A; Jurkiewicz, NH; Lopes, GS; Neto, AC; Smaili, SS; Vladimirova, I | 1 |
| Blackshaw, LA; Fraser, RJ; Frisby, CL; Schirmer, MB; Yeoh, EK | 1 |
| Eguchi, K; Ohtubo, Y; Yoshii, K | 1 |
| Osadchii, OE | 1 |
| Andersson, M; Aronsson, P; Delbro, DS; Giglio, D; Haraldsson, B; Tobin, G | 1 |
| Huang, TJ; Ko, WC; Lin, LH; Lin, YL; Wang, SH; Wu, SN | 1 |
| Advenier, C; Chen, HZ; Cui, YY; Devillier, P; Wang, H; Zhu, L | 1 |
| Chen, H; Chen, YH; Li, J; Li, L; Liang, L; Liu, X; Liu, Y; Ma, J; Peng, L; Qi, J; Wu, X; Xiao, J; Xu, J; Yang, Y; Zhang, Y; Zhao, C | 1 |
| Borella, TL; Colombari, DS; De Luca, LA; Menani, JV | 1 |
| Djokic, J; Grbovic, L; Nikolic, V; Pesic, S; Stoiljkovic, M | 1 |
| Bae, H; Choi, SM; Kim, HN; Kim, SK; Koo, S; Min, BI; Park, JH; Sun, B | 1 |
| Cueva-Rolón, R; Gómez-Martínez, LE | 1 |
| Choi, S; Choi, SJ; Jun, JY; Kim, SH; Parajuli, SP; So, KY; Sohn, HM; Yeum, CH; Yoon, PJ | 1 |
| Li, N; Sun, DW; Zhang, QG; Zhou, R; Zhu, FG | 1 |
| Orii, R; Sawamura, S; Sugawara, Y; Yamada, Y | 1 |
| Chess-Williams, R; Moro, C; Uchiyama, J | 1 |
| Abramochkin, DV; Nikolsky, EE; Nurullin, LF; Sukhova, GS; Tapilina, SV | 1 |
| Carew, MA; Fry, CH; Matharu, R; Young, JS | 1 |
| Abramochkin, DV; Sukhova, GS; Tapilina, SV | 1 |
| Parajuli, SP; Petkov, GV | 1 |
| Jackson, MW; Park, K; Park, S | 1 |
| Bertini, S; Delvescovo, B; Menozzi, A; Poli, E; Pozzoli, C; Serventi, P | 1 |
| Deng, J; Li, L; Shi, C; Song, B; Wu, Y; Zhang, X | 1 |
| Abramochkin, DV; Tapilina, SV | 1 |
| Ahn, TS; Hong, NR; Kim, BJ; Kim, SJ; Kwon, YK; Park, HS; Sung, SK | 1 |
| Miles, GB; Nascimento, F; Spindler, LRB | 1 |
1 review(s) available for methoctramine and piperidines
| Article | Year |
|---|---|
The influence of the muscarinic receptor subtypes on the sleep-wake cycle.
Topics: Animals; Diamines; Humans; Parasympatholytics; Piperidines; Receptors, Muscarinic; Sleep | 1993 |
126 other study(ies) available for methoctramine and piperidines
| Article | Year |
|---|---|
Characterization of the subtype of muscarinic receptor coupled to the stimulation of phosphoinositide hydrolysis in 132-1N1 human astrocytoma cells.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Astrocytoma; Atropine; Carbachol; Diamines; Humans; Hydrolysis; Parasympathomimetics; Phosphatidylinositols; Piperidines; Pirenzepine; Receptors, Muscarinic; Scopolamine; Tumor Cells, Cultured | 1992 |
Endogenous noradrenaline release from guinea-pig isolated trachea is inhibited by activation of M2 receptors.
Topics: Animals; Diamines; Dose-Response Relationship, Drug; Female; Guinea Pigs; In Vitro Techniques; Male; Muscarinic Antagonists; Norepinephrine; Oxotremorine; Parasympatholytics; Piperidines; Pirenzepine; Receptors, Muscarinic; Trachea | 1992 |
Pressor response to posterior hypothalamic administration of carbachol is mediated by muscarinic M3 receptor.
Topics: Animals; Atropine Derivatives; Blood Pressure; Carbachol; Diamines; Dose-Response Relationship, Drug; Hypothalamus, Posterior; Kinetics; Male; Microinjections; Muscarinic Antagonists; Parasympatholytics; Piperidines; Pirenzepine; Rats; Rats, Inbred Strains; Receptors, Muscarinic | 1992 |
Muscarinic receptor stimulated GTPase activity in synaptic membranes from bovine retina.
Topics: Animals; Cattle; Chromatography, Thin Layer; Diamines; Dose-Response Relationship, Drug; GTP Phosphohydrolases; Guanosine Triphosphate; Muscarinic Antagonists; Parasympatholytics; Parasympathomimetics; Piperidines; Pirenzepine; Receptors, Muscarinic; Retina; Stimulation, Chemical; Synaptic Membranes | 1992 |
Pharmacological profiles for rat cortical M1 and M2 muscarinic receptors using selective antagonists: comparison with N1E-115 muscarinic receptors.
Topics: Animals; Cerebral Cortex; Cyclic AMP; Diamines; In Vitro Techniques; Muscarinic Antagonists; Parasympatholytics; Phenethylamines; Phosphatidylinositols; Piperidines; Pirenzepine; Rats; Receptors, Muscarinic; Tumor Cells, Cultured | 1991 |
Pharmacological characterization of the vascular muscarinic receptors mediating relaxation and contraction in rabbit aorta.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Acetylcholine; Animals; Antihypertensive Agents; Aorta, Abdominal; Arecoline; Atropine; Diamines; Endothelium, Vascular; Hexamethonium; Hexamethonium Compounds; Indomethacin; Male; Muscarinic Antagonists; Muscle Contraction; Muscle Relaxation; Norepinephrine; Parasympatholytics; Piperidines; Pirenzepine; Rabbits; Receptors, Muscarinic | 1991 |
Pharmacological characterization of muscarinic receptor subtypes in rabbit isolated tissue preparations.
Topics: Animals; Aorta, Thoracic; Atropine; Diamines; Jejunum; Male; Muscarinic Antagonists; Muscle Contraction; Myocardium; Parasympatholytics; Piperidines; Pirenzepine; Rabbits; Receptors, Muscarinic; Vas Deferens; Vasodilation | 1991 |
The release of atrial natriuretic factor induced by central carbachol injection may be mediated by muscarinic M1 receptors.
Topics: Animals; Atrial Natriuretic Factor; Brain; Carbachol; Diamines; Dose-Response Relationship, Drug; Injections, Intraventricular; Injections, Subcutaneous; Male; Parasympatholytics; Piperidines; Pirenzepine; Rats; Rats, Inbred Strains; Receptors, Muscarinic | 1991 |
Methoctramine, a cardioselective antagonist: muscarinic receptor mediating prostaglandin synthesis in isolated rabbit heart.
Topics: 6-Ketoprostaglandin F1 alpha; Acetylcholine; Animals; Arachidonic Acid; Arachidonic Acids; Arecoline; Coronary Circulation; Diamines; Heart; Heart Rate; In Vitro Techniques; Isoproterenol; Male; Myocardium; Parasympatholytics; Piperidines; Prostaglandins; Rabbits; Receptors, Muscarinic | 1991 |
Differential effects of M2 and M3 muscarinic antagonists on the sleep-wake cycle.
Topics: Animals; Cerebral Ventricles; Diamines; Dose-Response Relationship, Drug; Injections, Intraventricular; Male; Piperidines; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Reference Values; Sleep; Sympatholytics; Wakefulness | 1991 |
Characterization of muscarinic receptors in dog tracheal smooth muscle cells.
Topics: Animals; Atropine; Carbachol; Diamines; Dogs; In Vitro Techniques; Kinetics; Muscle, Smooth; N-Methylscopolamine; Parasympatholytics; Piperidines; Pirenzepine; Receptors, Muscarinic; Scopolamine Derivatives; Trachea | 1991 |
Prejunctional muscarinic receptors on cholinergic nerves in guinea pig airways are of the M2 subtype.
Topics: Animals; Diamines; Electric Stimulation; Gallamine Triethiodide; Guinea Pigs; In Vitro Techniques; Male; Parasympathetic Nervous System; Parasympatholytics; Piperidines; Pirenzepine; Receptors, Muscarinic; Trachea | 1991 |
Natriuresis, kaliuresis and antidiuresis induced by central carbachol injection are mediated by muscarinic M1 receptors.
Topics: Animals; Carbachol; Diamines; Diuresis; Dose-Response Relationship, Drug; Injections, Intraventricular; Male; Muscarinic Antagonists; Natriuresis; Piperidines; Potassium; Rats; Rats, Inbred Strains; Receptors, Muscarinic | 1991 |
Muscarinic M1 receptors stimulate phosphoinositide hydrolysis in bovine cerebral arteries.
Topics: Animals; Cattle; Cerebral Arteries; Diamines; Endothelium, Vascular; Hydrolysis; Inositol Phosphates; Kinetics; Oxotremorine; Phosphatidylinositols; Piperidines; Pirenzepine; Receptors, Muscarinic; Signal Transduction | 1990 |
The binding of [3H]4-diphenylacetoxy-N-methylpiperidine methiodide to longitudinal ileal smooth muscle muscarinic receptors.
Topics: Animals; Binding, Competitive; Diamines; Gallamine Triethiodide; Guinea Pigs; Ileum; In Vitro Techniques; Male; Muscle, Smooth; Piperidines; Pirenzepine; Receptors, Muscarinic | 1990 |
Autoradiographic visualization of muscarinic receptor subtypes in human and guinea pig lung.
Topics: Animals; Autoradiography; Binding Sites; Diamines; Guinea Pigs; Humans; Lung; Parasympatholytics; Piperidines; Pirenzepine; Quinuclidinyl Benzilate; Radioligand Assay; Receptors, Muscarinic; Tritium | 1990 |
[3H]N-methylscopolamine binding studies reveal M2 and M3 muscarinic receptor subtypes on cerebellar granule cells in primary culture.
Topics: Animals; Atropine; Binding, Competitive; Cell Survival; Cells, Cultured; Cerebellum; Diamines; Granulocytes; N-Methylscopolamine; Parasympatholytics; Piperidines; Pirenzepine; Receptors, Muscarinic; Scopolamine Derivatives; Tritium | 1990 |
The allosteric binding profile of himbacine: a comparison with other cardioselective muscarinic antagonists.
Topics: Alkaloids; Allosteric Regulation; Animals; Atropine; Binding, Competitive; Diamines; Dose-Response Relationship, Drug; Furans; Gallamine Triethiodide; Male; Myocardium; N-Methylscopolamine; Naphthalenes; Piperidines; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Scopolamine Derivatives | 1990 |
Binding of selective antagonists to four muscarinic receptors (M1 to M4) in rat forebrain.
Topics: Alkaloids; Animals; Brain; Diamines; Furans; Humans; Hybrid Cells; N-Methylscopolamine; Naphthalenes; Parasympatholytics; Piperidines; Rats; Receptors, Muscarinic; Scopolamine Derivatives; Tumor Cells, Cultured | 1990 |
Characterization of the striatal M2 muscarinic receptor mediating inhibition of cyclic AMP using selective antagonists: a comparison with the brainstem M2 receptor.
Topics: Animals; Brain Stem; Corpus Striatum; Cyclic AMP; Diamines; Parasympatholytics; Piperidines; Pirenzepine; Rats; Receptors, Muscarinic | 1989 |
Affinity profiles of hexahydro-sila-difenidol analogues at muscarinic receptor subtypes.
Topics: Animals; Diamines; Female; Ganglia, Sympathetic; Guinea Pigs; Heart; Ileum; In Vitro Techniques; Male; Muscle, Smooth, Vascular; Piperidines; Pirenzepine; Rabbits; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Vas Deferens | 1989 |
Methoctramine and hexahydrodifenidol antagonise two muscarinic responses on the rat superior cervical ganglion with opposite selectivity.
Topics: Animals; Diamines; Ganglia, Sympathetic; In Vitro Techniques; Male; Membrane Potentials; Muscarine; Piperidines; Rats; Rats, Inbred Strains; Receptors, Muscarinic | 1989 |
The interaction of methoctramine and himbacine at atrial, smooth muscle and endothelial muscarinic receptors in vitro.
Topics: Alkaloids; Animals; Diamines; Drug Interactions; Endothelium; Furans; Guinea Pigs; Heart Atria; In Vitro Techniques; Male; Muscle, Smooth; Naphthalenes; Piperidines; Rats; Rats, Inbred Strains; Receptors, Muscarinic | 1988 |
Muscarinic receptor subtypes mediating vasodilation in the pulmonary artery.
Topics: Animals; Binding Sites; Cell Membrane; Diamines; Endothelium, Vascular; Lung; Male; Piperidines; Pirenzepine; Pulmonary Artery; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Vasodilation | 1988 |
M2-type muscarinic receptors mediate prejunctional inhibition of norepinephrine release in the human iris-ciliary body.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Carbachol; Child; Ciliary Body; Diamines; Dose-Response Relationship, Drug; Electric Stimulation; Humans; In Vitro Techniques; Iris; Middle Aged; Muscarine; Norepinephrine; Pilocarpine; Piperidines; Pirenzepine; Receptors, Muscarinic | 1994 |
Characterization of muscarinic receptors mediating relaxation and contraction in the rat iris dilator muscle.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Acetylcholine; Alkaloids; Animals; Arecoline; Bethanechol; Carbachol; Diamines; Dose-Response Relationship, Drug; Furans; Ganglia, Parasympathetic; Ganglionectomy; Iris; Male; Methacholine Chloride; Muscarinic Agonists; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Naphthalenes; Parasympatholytics; Pilocarpine; Piperidines; Pirenzepine; Rats; Rats, Wistar; Receptors, Muscarinic | 1995 |
Role of muscarinic M2 and M3 receptors in guinea-pig trachea: effects of receptor alkylation.
Topics: Alkylation; Animals; Diamines; Dioxolanes; Diphenylacetic Acids; Drug Interactions; Guinea Pigs; Histamine; Isoproterenol; Kinetics; Male; Muscle Contraction; Muscle, Smooth; Oxotremorine; Piperidines; Receptors, Muscarinic; Stimulation, Chemical; Trachea | 1995 |
Mode of antagonism of methoctramine, AF-DX 116 and hexahydrosiladifenidol in guinea-pig left atrium and ileum: comparison of Schild and resultant analysis.
Topics: Animals; Diamines; Guinea Pigs; Ileum; In Vitro Techniques; Male; Muscarinic Agonists; Muscarinic Antagonists; Muscle Contraction; Muscle, Smooth; Myocardial Contraction; Parasympatholytics; Piperidines; Pirenzepine | 1995 |
Release of endogenous acetylcholine from a vascularly perfused rat stomach in vitro; inhibition by M3 muscarinic autoreceptors and alpha-2 adrenoceptors.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Acetylcholine; Adrenergic alpha-Antagonists; Animals; Atropine; Calcium; Clonidine; Diamines; Drug Interactions; Electric Stimulation; Gastric Mucosa; Hexamethonium; Hexamethonium Compounds; Male; Muscarinic Antagonists; Oxotremorine; Parasympatholytics; Perfusion; Phenylephrine; Piperidines; Pirenzepine; Rats; Rats, Wistar; Receptors, Adrenergic, alpha; Receptors, Muscarinic; Stomach; Sympathetic Nervous System; Tetrodotoxin; Vagus Nerve | 1993 |
Hypotensive effect of an M2-selective muscarinic antagonist in anaesthetized guinea-pigs.
Topics: Animals; Atropine; Blood Pressure; Depression, Chemical; Diamines; Guinea Pigs; Heart Rate; Male; Muscarinic Antagonists; Norepinephrine; Parasympatholytics; Piperidines; Pirenzepine; Receptors, Muscarinic | 1995 |
Pertussis toxin-sensitive muscarinic relaxation in the rat iris dilator muscle.
Topics: Acetylcholine; Alkaloids; Animals; Atropine; Diamines; Dose-Response Relationship, Drug; Furans; GTP-Binding Proteins; In Vitro Techniques; Iris; Male; Microinjections; Muscarinic Antagonists; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Naphthalenes; Parasympatholytics; Pertussis Toxin; Phentolamine; Piperidines; Pirenzepine; Rats; Rats, Wistar; Receptors, Muscarinic; Virulence Factors, Bordetella | 1995 |
Dysfunction of muscarinic M2 receptors after the early allergic reaction: possible contribution to bronchial hyperresponsiveness in allergic guinea-pigs.
Topics: Administration, Inhalation; Allergens; Animals; Asthma; Benzodiazepinones; Bronchial Hyperreactivity; Diamines; Disease Models, Animal; Electric Stimulation; Female; Gallamine Triethiodide; Guinea Pigs; Heart; Histamine; Hypersensitivity; In Vitro Techniques; Male; Muscarinic Antagonists; Muscle, Smooth; Neuromuscular Junction; Parasympatholytics; Pilocarpine; Piperidines; Pirenzepine; Receptors, Muscarinic; Trachea | 1995 |
Regional differences in motor responsiveness to antimuscarinic drugs in rabbit isolated small and large intestine.
Topics: Animals; Atropine; Benzodiazepinones; Diamines; Dose-Response Relationship, Drug; Gastrointestinal Motility; Intestine, Large; Intestine, Small; Male; Muscarinic Antagonists; Parasympatholytics; Piperidines; Pirenzepine; Rabbits; Receptors, Muscarinic | 1995 |
Methoctramine induces nonspecific airway hyperresponsiveness in vivo.
Topics: Aerosols; Albuterol; Animals; Arachidonic Acid; Atropine; Bronchial Hyperreactivity; Bronchoconstriction; Diamines; Drug Synergism; Gallamine Triethiodide; Guinea Pigs; Histamine; Male; Muscarinic Antagonists; Ovalbumin; Parasympatholytics; Piperazines; Piperidines; Platelet Activating Factor; Propranolol; Receptors, Muscarinic | 1994 |
Antimuscarinic action of liriodenine, isolated from Fissistigma glaucescens, in canine tracheal smooth muscle.
Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Antineoplastic Agents, Phytogenic; Aporphines; Binding, Competitive; Carbachol; Cells, Cultured; Cyclic AMP; Diamines; Dogs; Female; Hydrolysis; Inositol Phosphates; Male; Muscarinic Antagonists; Muscle Contraction; Muscle, Smooth; Parasympatholytics; Phosphatidylinositols; Piperidines; Plants, Medicinal; Receptors, Muscarinic; Trachea | 1994 |
Vitamin D status modulates rat colonic M3 muscarinic receptor characteristics and coupling to guanylate cyclase.
Topics: Animals; Atropine; Colon; Diamines; Enzyme Activation; Guanylate Cyclase; Male; Muscarinic Antagonists; Nutritional Status; Parasympatholytics; Piperidines; Pirenzepine; Quinuclidinyl Benzilate; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic; Vitamin D | 1994 |
In vivo study of the role of muscarinic receptors in the parasympathetic control of rabbit colonic motility.
Topics: Action Potentials; Animals; Colon; Diamines; Electric Stimulation; Gallamine Triethiodide; Gastrointestinal Motility; Male; Muscle, Smooth; Parasympathetic Nervous System; Piperidines; Pirenzepine; Rabbits; Receptors, Muscarinic; Vagus Nerve | 1994 |
Effects of muscarinic M2 and M3 receptor stimulation and antagonism on responses to isoprenaline of guinea-pig trachea in vitro.
Topics: Animals; Diamines; Dioxolanes; Guinea Pigs; Histamine; In Vitro Techniques; Isometric Contraction; Isoproterenol; Male; Muscarinic Antagonists; Muscle Relaxation; Muscle, Smooth; Parasympatholytics; Piperidines; Receptors, Muscarinic; Trachea | 1994 |
Diabetes-induced alterations in the properties of muscarinic cholinergic receptors in rat vas deferens.
Topics: Animals; Atropine; Binding, Competitive; Diabetes Mellitus, Experimental; Diamines; Insulin; Male; Parasympatholytics; Piperidines; Pirenzepine; Quinuclidinyl Benzilate; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic; Up-Regulation; Vas Deferens | 1994 |
Selective blockade of different brain stem muscarinic receptor subtypes: effects on the sleep-wake cycle.
Topics: Animals; Brain Stem; Carbachol; Diamines; Electroencephalography; Male; Microinjections; Muscarinic Antagonists; Parasympatholytics; Piperidines; Pirenzepine; Polysomnography; Rats; Reticular Formation; Sleep; Wakefulness | 1994 |
Reversibility of diabetes- and diuresis-induced alterations in rat bladder dome muscarinic receptors.
Topics: Animals; Binding, Competitive; Body Weight; Cell Membrane; Diabetes Mellitus, Experimental; Diamines; Diuresis; Drinking Behavior; Insulin; Kinetics; Male; Myocardium; Organ Size; Parasympatholytics; Piperidines; Pirenzepine; Prostate; Quinuclidinyl Benzilate; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic; Sucrose; Testosterone; Up-Regulation; Urinary Bladder | 1994 |
Selective inactivation of muscarinic M2 and M3 receptors in guinea-pig ileum and atria in vitro.
Topics: Alkylating Agents; Animals; Atropine; Diamines; Dioxolanes; Diphenylacetic Acids; Guinea Pigs; Heart; Heart Atria; Ileum; In Vitro Techniques; Isometric Contraction; Male; Muscarinic Antagonists; Muscle, Smooth; Parasympatholytics; Phenoxybenzamine; Pilocarpine; Piperidines; Receptors, Muscarinic | 1993 |
Cholinergic M2 muscarinic receptor-mediated inhibition of endogenous noradrenaline release from the isolated vascularly perfused rat stomach.
Topics: Animals; Arteries; Atrial Function; Atropine; Depression, Chemical; Diamines; Electric Stimulation; Ethylmaleimide; Heart Atria; Male; Myocardial Contraction; Nerve Endings; Norepinephrine; Oxotremorine; Parasympatholytics; Perfusion; Pertussis Toxin; Phentolamine; Piperidines; Pirenzepine; Rats; Rats, Wistar; Receptors, Muscarinic; Stomach; Sympathetic Nervous System; Vagus Nerve; Virulence Factors, Bordetella | 1993 |
In vivo and in vitro effects of muscarinic receptor antagonists on contractions and release of [3H]acetylcholine in the rabbit urinary bladder.
Topics: Acetylcholine; Animals; Carbachol; Diamines; Female; Gallamine Triethiodide; Muscarinic Antagonists; Muscle Contraction; Parasympatholytics; Piperidines; Pirenzepine; Rabbits; Receptors, Muscarinic; Tritium; Urinary Bladder | 1995 |
Muscarinic receptor subtypes mediating catecholamine secretion and increase in intracellular Ca2+ concentration in adrenal chromaffin cells of the guinea pig.
Topics: Adrenal Medulla; Animals; Calcium; Cells, Cultured; Cholinergic Agents; Chromatography, High Pressure Liquid; Diamines; Dose-Response Relationship, Drug; Epinephrine; Female; Guinea Pigs; Kinetics; Male; Methacholine Chloride; Muscarine; Norepinephrine; Oxotremorine; Parasympatholytics; Piperidines; Pirenzepine; Receptors, Muscarinic | 1995 |
On muscarinic control of neurogenic mucus secretion in ferret trachea.
Topics: Animals; Diamines; Electric Stimulation; Ferrets; In Vitro Techniques; Male; Mucus; Muscarinic Antagonists; Muscle, Smooth; Piperidines; Pirenzepine; Quinuclidinyl Benzilate; Radioligand Assay; Receptors, Muscarinic; Scopolamine; Sulfates; Sulfur Radioisotopes; Trachea; Tritium | 1996 |
Acetylcholine stimulates growth hormone secretion in the neonatal rat pituitary.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Acetylcholine; Age Factors; Animals; Animals, Newborn; Atropine; Diamines; Dose-Response Relationship, Drug; Female; Growth Hormone; Male; Muscarinic Agonists; Muscarinic Antagonists; Parasympatholytics; Piperidines; Pirenzepine; Pituitary Gland; Rats; Rats, Wistar | 1996 |
Pharmacologic characterization of muscarine receptor subtypes in rat gastric fundus mediating contractile responses.
Topics: Acetylcholine; Animals; Atropine; Diamines; Female; Gastric Fundus; Gastrointestinal Motility; Male; Muscarinic Antagonists; Piperazines; Piperidines; Pirenzepine; Rats; Rats, Wistar; Receptors, Muscarinic | 1997 |
Pharmacological characterization of the muscarinic receptor subtypes responsible for the contractile response in the rat urinary bladder.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Acetylcholine; Analysis of Variance; Animals; Bethanechol; Diamines; Dose-Response Relationship, Drug; Female; Gallamine Triethiodide; Muscarinic Agonists; Muscarinic Antagonists; Muscle Contraction; Muscle, Smooth; Nicotinic Antagonists; Oxotremorine; Parasympatholytics; Piperidines; Rats; Rats, Wistar; Receptors, Muscarinic; Structure-Activity Relationship; Urinary Bladder | 1997 |
Cholinergic modulation of electrogenic ion transport in different regions of the rat small intestine.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Analysis of Variance; Animals; Atropine; Bethanechol; Carbachol; Chlorides; Diamines; Duodenum; Ileum; Intestinal Mucosa; Ion Transport; Jejunum; Male; Muscarinic Agonists; Muscarinic Antagonists; Piperidines; Pirenzepine; Rats; Rats, Wistar; Receptor, Muscarinic M3; Receptors, Muscarinic; Structure-Activity Relationship; Tetrodotoxin | 1997 |
M3 muscarinic receptor-mediated enhancement of NMDA-evoked adenosine release in rat cortical slices in vitro.
Topics: Adenosine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Atropine; Carbachol; Cerebral Cortex; Diamines; Drug Synergism; In Vitro Techniques; Kinetics; Magnesium; Male; Muscarinic Agonists; Muscarinic Antagonists; N-Methylaspartate; Piperidines; Pirenzepine; Rats; Rats, Wistar; Receptor, Muscarinic M3; Receptors, Muscarinic | 1997 |
Differentiation of muscarinic receptors mediating negative chronotropic and vasoconstrictor responses to acetylcholine in isolated rat hearts.
Topics: Acetylcholine; Animals; Atropine; Coronary Vessels; Depression, Chemical; Diamines; Heart Rate; In Vitro Techniques; Male; Pertussis Toxin; Piperidines; Pirenzepine; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic; Vasoconstriction; Virulence Factors, Bordetella | 1997 |
Muscarinic facilitation of GABA release in substantia gelatinosa of the rat spinal dorsal horn.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Animals; Atropine; Carbachol; Diamines; Evoked Potentials; gamma-Aminobutyric Acid; In Vitro Techniques; Interneurons; Muscarinic Agonists; Neostigmine; Neurons; Parasympatholytics; Piperidines; Pirenzepine; Rats; Receptor, Muscarinic M1; Receptors, Muscarinic; Substantia Gelatinosa; Synaptic Transmission; Tetrodotoxin | 1998 |
Characterization of muscarinic receptors mediating the contraction of the urinary detrusor muscle in cynomolgus monkeys and guinea pigs.
Topics: Animals; Carbachol; Diamines; Female; Guinea Pigs; Macaca fascicularis; Male; Muscarinic Agonists; Muscarinic Antagonists; Muscle Contraction; Muscle, Smooth; Piperidines; Pirenzepine; Receptor, Muscarinic M2; Receptors, Muscarinic; Urinary Bladder | 1998 |
Autoradiographic localisation of muscarinic cholinergic receptor subtypes in human placenta.
Topics: Adult; Binding, Competitive; Diamines; Female; Humans; Microvilli; Muscarinic Antagonists; Piperidines; Pirenzepine; Placenta; Pregnancy; Receptors, Muscarinic; Trophoblasts; Tropicamide | 1998 |
Pressor and bradycardic effects of tacrine and other acetylcholinesterase inhibitors in the rat.
Topics: Adrenergic Antagonists; Animals; Antidiuretic Hormone Receptor Antagonists; Atropine; Atropine Derivatives; Blood Pressure; Carbamates; Cardiovascular Agents; Chlorisondamine; Cholinergic Antagonists; Cholinesterase Inhibitors; Diamines; Diastole; Dose-Response Relationship, Drug; Heart Rate; Male; Phenylcarbamates; Physostigmine; Piperidines; Pirenzepine; Rats; Rats, Wistar; Rivastigmine; Systole; Tacrine | 1998 |
Prejunctional muscarinic receptors modulating acetylcholine release in rabbit detrusor smooth muscles.
Topics: Acetylcholine; Animals; Chromatography, High Pressure Liquid; Culture Techniques; Diamines; Female; Muscarinic Antagonists; Muscle Contraction; Muscle, Skeletal; Muscle, Smooth; Parasympatholytics; Piperidines; Pirenzepine; Rabbits; Receptors, Muscarinic; Reference Values | 1998 |
M2 receptors in genito-urinary smooth muscle pathology.
Topics: Animals; Binding Sites; Carbachol; Diamines; Dose-Response Relationship, Drug; Female; Hypertrophy; Muscarinic Agonists; Muscarinic Antagonists; Muscle Contraction; Muscle Denervation; Muscle, Smooth; Organ Size; Piperidines; Rats; Rats, Sprague-Dawley; Receptor, Muscarinic M2; Receptors, Muscarinic; Spinal Cord Injuries; Urinary Bladder; Urinary Bladder, Neurogenic | 1999 |
The design of novel methoctramine-related tetraamines as muscarinic receptor subtype selective antagonists.
Topics: Animals; Atrial Function; Benzodiazepines; Benzodiazepinones; Diamines; Drug Design; Guinea Pigs; Heart Atria; Ileum; Muscarinic Antagonists; Muscle Contraction; Muscle, Smooth; Parasympatholytics; Piperidines; Pirenzepine; Rats; Receptors, Muscarinic; Structure-Activity Relationship; Submandibular Gland; Trachea | 1995 |
Activation of muscarinic M3-like receptors and beta-adrenoceptors, but not M2-like muscarinic receptors or alpha-adrenoceptors, directly modulates corticostriatal neurotransmission in vitro.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; 6-Cyano-7-nitroquinoxaline-2,3-dione; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic beta-Agonists; Adrenergic Fibers; Animals; Carbachol; Cerebral Cortex; Cholinergic Fibers; Corpus Striatum; Diamines; Excitatory Amino Acid Agonists; Excitatory Postsynaptic Potentials; Glutamic Acid; Imidazoles; Isoproterenol; Male; Medetomidine; Mice; Mice, Inbred DBA; Muscarinic Agonists; Muscarinic Antagonists; Phenylephrine; Piperidines; Pirenzepine; Pyrrolidinones; Receptor, Muscarinic M2; Receptor, Muscarinic M3; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Receptors, AMPA; Receptors, Muscarinic; Scopolamine; Synaptic Transmission | 1999 |
Subtypes of muscarinic receptors regulating gallbladder cholinergic contractions.
Topics: Acetylcholine; Animals; Atropine; Diamines; Electric Stimulation; Gallbladder; Guinea Pigs; Hexamethonium; Muscarinic Antagonists; Muscle Contraction; Parasympatholytics; Piperidines; Pirenzepine; Receptor, Muscarinic M1; Receptor, Muscarinic M2; Receptor, Muscarinic M3; Receptors, Muscarinic; Tetrodotoxin; Tropicamide | 1999 |
Presynaptic muscarinic (M3) receptors reduce excitatory transmission in dopamine neurons of the rat mesencephalon.
Topics: 4-Aminopyridine; Acetylcholine; Animals; Atropine; Carbachol; Diamines; Dicyclomine; Dopamine; Electric Stimulation; Excitatory Postsynaptic Potentials; Mesencephalon; Muscarine; Muscarinic Agonists; Muscarinic Antagonists; Neurons; Parasympatholytics; Physostigmine; Piperidines; Pirenzepine; Presynaptic Terminals; Rats; Rats, Sprague-Dawley; Rats, Wistar; Reaction Time; Receptor, Muscarinic M3; Receptors, Muscarinic; Synaptic Transmission; Tetrodotoxin | 1999 |
Ascending neural pathways in the isolated guinea-pig ileum: effect of muscarinic M1, M2 and M3 cholinergic antagonists.
Topics: Acetylcholine; Afferent Pathways; Anal Canal; Animals; Diamines; Electric Stimulation; Guinea Pigs; Ileum; In Vitro Techniques; Male; Mouth; Muscarinic Antagonists; Muscle Contraction; Muscle, Smooth; Piperidines; Pirenzepine | 1999 |
Muscarinic cholinoceptor subtypes mediating tracheal smooth muscle contraction and inositol phosphate generation in guinea pig and rat.
Topics: Animals; Atropine; Diamines; Guinea Pigs; In Vitro Techniques; Inositol Phosphates; Male; Muscarinic Antagonists; Muscle Contraction; Muscle, Smooth; Piperidines; Pirenzepine; Rats; Rats, Wistar; Receptors, Muscarinic; Trachea | 1999 |
M2 muscarinic receptor subtype in the feline medial pontine reticular formation modulates the amount of rapid eye movement sleep.
Topics: Animals; Bethanechol; Cats; Diamines; Muscarinic Agonists; Muscarinic Antagonists; Piperidines; Pons; Receptors, Muscarinic; Respiration; Reticular Formation; Sleep, REM; Time Factors; Wakefulness | 1999 |
Acetylcholine-induced contractions in the porcine internal mammary artery: possible role of muscarinic receptors.
Topics: Acetylcholine; Animals; Diamines; Endothelium, Vascular; In Vitro Techniques; Mammary Arteries; Muscle Contraction; Muscle, Smooth, Vascular; Parasympatholytics; Piperidines; Pirenzepine; Receptors, Muscarinic; Swine | 1999 |
Selective restoration of calcium coupling to muscarinic M(3) receptors in contractile cultured airway myocytes.
Topics: Acetylcholine; Animals; Atropine; Blood Proteins; Blotting, Western; Bradykinin; Calcium; Calcium Channels; Cells, Cultured; Diamines; Dogs; Dose-Response Relationship, Drug; Fluorescent Dyes; Fura-2; Inositol 1,4,5-Trisphosphate Receptors; Macrocyclic Compounds; Muscarinic Antagonists; Muscle, Smooth; Oxazoles; Parasympatholytics; Phenotype; Piperidines; Pirenzepine; Receptor, Muscarinic M3; Receptors, Bradykinin; Receptors, Cytoplasmic and Nuclear; Receptors, Muscarinic; Trachea; Vasodilator Agents | 2000 |
Influence of gender and the oestrous cycle on in vitro contractile responses of the rat urinary bladder to cholinergic stimulation.
Topics: Animals; Carbachol; Cholinergic Agonists; Diamines; Electric Stimulation; Estrus; Female; Male; Muscarinic Antagonists; Parasympatholytics; Piperidines; Pirenzepine; Rats; Rats, Sprague-Dawley; Receptors, Cholinergic; Sex Characteristics; Time Factors; Urinary Bladder; Uterine Contraction | 2000 |
Efficacy of muscarinic stimulation and mode of excitation-contraction coupling in bovine trachealis muscle.
Topics: Acetylcholine; Animals; Calcium; Cattle; Cromakalim; Diamines; Dose-Response Relationship, Drug; Drug Interactions; In Vitro Techniques; Muscarinic Agonists; Muscle Contraction; Muscle, Smooth; Nifedipine; Phenoxybenzamine; Pilocarpine; Piperidines; Pirenzepine; Receptors, Muscarinic; Stress, Mechanical; Tetraethylammonium; Trachea | 2000 |
Human esophageal smooth muscle cells express muscarinic receptor subtypes M(1) through M(5).
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Acetylcholine; Blotting, Western; Calcium; Calcium Channel Agonists; Calcium Signaling; Cells, Cultured; Diamines; DNA Primers; Esophagus; Humans; Immunohistochemistry; Muscarinic Antagonists; Muscle Fibers, Skeletal; Muscle, Smooth; Parasympatholytics; Piperidines; Pirenzepine; Receptor, Muscarinic M1; Receptor, Muscarinic M2; Receptor, Muscarinic M3; Receptor, Muscarinic M4; Receptor, Muscarinic M5; Receptors, Muscarinic; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Vasodilator Agents | 2000 |
The role of M(2)-muscarinic receptors in mediating contraction of the pig urinary bladder in vitro.
Topics: Animals; Benzofurans; Binding, Competitive; Carbachol; Diamines; Dose-Response Relationship, Drug; Female; In Vitro Techniques; Membranes; Muscarinic Antagonists; Muscle Contraction; Piperidines; Pyrrolidines; Quinuclidinyl Benzilate; Radioligand Assay; Receptor, Muscarinic M2; Receptor, Muscarinic M3; Receptors, Muscarinic; Swine; Tritium; Urinary Bladder | 2000 |
Functional characterization of rat submaxillary gland muscarinic receptors using microphysiometry.
Topics: Alkaloids; Animals; Atropine; Benzhydryl Compounds; Benzodiazepinones; Binding, Competitive; Biosensing Techniques; Carbachol; Cholinergic Agonists; Cresols; Diamines; Dose-Response Relationship, Drug; Furans; Male; Mandelic Acids; Muscarinic Antagonists; Naphthalenes; Phenethylamines; Phenylpropanolamine; Piperidines; Pirenzepine; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic; Submandibular Gland; Tolterodine Tartrate | 2001 |
The antinociceptive and sedative effects of carbachol and oxycodone administered into brainstem pontine reticular formation and spinal subarachnoid space in rats.
Topics: Analgesics, Non-Narcotic; Analgesics, Opioid; Animals; Atropine; Behavior, Animal; Carbachol; Cholinergic Agonists; Conscious Sedation; Diamines; Injections, Spinal; Male; Microinjections; Motor Activity; Muscarinic Antagonists; Pain Threshold; Piperidines; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic; Reticular Formation; Subarachnoid Space | 2001 |
Effect of M2 and M3 muscarinic receptors on airway responsiveness to carbachol in bronchial-hypersensitive (BHS) and bronchial-hyposensitive (BHR) guinea pigs.
Topics: Animals; Bronchial Hyperreactivity; Carbachol; Diamines; Gene Expression; Guinea Pigs; Lung; Male; Muscarinic Antagonists; Muscle Contraction; Muscle, Smooth; Piperidines; Receptor, Muscarinic M2; Receptor, Muscarinic M3; Receptors, Muscarinic; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Trachea | 2001 |
Pharmacological characterization of muscarinic receptors in mouse isolated urinary bladder smooth muscle.
Topics: Acetylcholine; Animals; Carbachol; Diamines; Dioxolanes; Dose-Response Relationship, Drug; In Vitro Techniques; Male; Mice; Mice, Inbred C57BL; Muscarinic Agonists; Muscarinic Antagonists; Muscle Contraction; Muscle, Smooth; Oxotremorine; Pilocarpine; Piperidines; Receptors, Muscarinic; Urinary Bladder | 2001 |
Muscarinic receptors control K+ secretion in inner ear strial marginal cells.
Topics: Adrenergic beta-Agonists; Animals; Atropine; Calcium; Carbachol; Cholinergic Agonists; Cloning, Molecular; Cyclic AMP; Diamines; Dose-Response Relationship, Drug; Gerbillinae; Isoproterenol; Muscarinic Antagonists; Parasympatholytics; Piperidines; Pirenzepine; Potassium; Receptors, Muscarinic; Reverse Transcriptase Polymerase Chain Reaction; Stria Vascularis | 2001 |
Characterization of muscarinic acetylcholine receptors in the rat epididymis.
Topics: Animals; Atropine; Cell Membrane; Diamines; Epididymis; Male; Muscarinic Antagonists; Piperidines; Pirenzepine; Quinuclidinyl Benzilate; Rats; Rats, Wistar; Receptors, Muscarinic; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tritium | 2001 |
Muscarinic receptor subtypes mediating vasorelaxation of the perforating branch of the human internal mammary artery.
Topics: Acetylcholine; Adult; Aged; Atropine; Diamines; Dose-Response Relationship, Drug; Endothelium, Vascular; Female; Humans; In Vitro Techniques; Mammary Arteries; Middle Aged; Muscarinic Antagonists; Piperidines; Pirenzepine; Receptors, Muscarinic; Vasodilation; Vasodilator Agents | 2001 |
On the functional role of muscarinic M2 receptors in cholinergic and purinergic responses in the rat urinary bladder.
Topics: 2-Chloroadenosine; Adenosine; Adenosine Triphosphate; Animals; Carbachol; Diamines; Dose-Response Relationship, Drug; In Vitro Techniques; Male; Muscarinic Agonists; Muscarinic Antagonists; Muscle Contraction; Piperidines; Pirenzepine; Purinergic Agonists; Purinergic Antagonists; Rats; Rats, Sprague-Dawley; Receptor, Muscarinic M2; Receptors, Muscarinic; Receptors, Purinergic; Theophylline; Urinary Bladder | 2001 |
The role of M2 muscarinic receptor subtypes in mediating contraction of the pig bladder base after cyclic adenosine monophosphate elevation and/or selective M3 inactivation.
Topics: Animals; Cyclic AMP; Diamines; Female; In Vitro Techniques; Isoproterenol; Muscle Contraction; Muscle, Smooth; Piperidines; Potassium Chloride; Receptor, Muscarinic M2; Receptor, Muscarinic M3; Receptors, Muscarinic; Swine; Urinary Bladder | 2002 |
Muscarinic receptor subtypes mediate stimulatory and paradoxical inhibitory effects on an insulin-secreting beta cell line.
Topics: Acetylcholine; Animals; Cell Line; Diamines; Insulin; Insulin Secretion; Islets of Langerhans; Muscarinic Antagonists; Piperidines; Pirenzepine; Receptors, Muscarinic; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2002 |
Acetylcholine-induced contractions in the perforating branch of the human internal mammary artery: protective role of the vascular endothelium.
Topics: Acetylcholine; Atropine; Diamines; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Inhibitors; Female; Humans; In Vitro Techniques; Indomethacin; Mammary Arteries; Middle Aged; Muscarinic Antagonists; Nitric Oxide Synthase; omega-N-Methylarginine; Phenylephrine; Piperidines; Pirenzepine; Vasoconstriction; Vasoconstrictor Agents; Vasodilator Agents | 2002 |
Studies of muscarinic receptor subtypes in salivary gland function in anaesthetized rats.
Topics: Acetylcholine; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Analysis of Variance; Anesthesia; Animals; Blood Pressure; Diamines; Dose-Response Relationship, Drug; Drug Interactions; Female; Muscarinic Antagonists; Parotid Gland; Phentolamine; Piperidines; Pirenzepine; Propranolol; Rats; Rats, Sprague-Dawley; Receptor, Muscarinic M3; Receptors, Muscarinic; Saliva; Salivary Glands; Sublingual Gland; Submandibular Gland; Vasodilator Agents | 2002 |
A mechanism for rapacuronium-induced bronchospasm: M2 muscarinic receptor antagonism.
Topics: Animals; Atracurium; Binding, Competitive; Bronchial Spasm; Cell Membrane; CHO Cells; Cricetinae; Diamines; Indicators and Reagents; Muscarinic Antagonists; Neuromuscular Nondepolarizing Agents; Piperidines; Quinuclidinyl Benzilate; Radioligand Assay; Receptor, Muscarinic M2; Receptor, Muscarinic M3; Receptors, Muscarinic; Vecuronium Bromide | 2003 |
Characterization of muscarinic receptor subtypes in the rostral ventrolateral medulla and effects on morphine-induced antinociception in rats.
Topics: Analgesics, Opioid; Animals; Atropine; Diamines; Male; Mecamylamine; Medulla Oblongata; Microinjections; Morphine; Naloxone; Narcotic Antagonists; Pain Measurement; Piperidines; Pirenzepine; Rats; Rats, Wistar; Receptor, Muscarinic M1; Receptor, Muscarinic M2; Receptor, Muscarinic M3; Time Factors | 2003 |
The cholinomimetic agent bethanechol activates IK(ACh) in feline atrial myocytes.
Topics: Animals; Barium; Bee Venoms; Benzodiazepines; Bethanechol; Cats; Cholinergic Agents; Diamines; Heart Atria; In Vitro Techniques; Membrane Potentials; Muscarinic Agonists; Muscarinic Antagonists; Muscle Cells; Phenethylamines; Piperidines; Potassium Channel Blockers; Potassium Channels, Inwardly Rectifying; Receptor, Muscarinic M1; Receptor, Muscarinic M2; Receptor, Muscarinic M3; Receptor, Muscarinic M4; Sulfonamides; Tropicamide | 2003 |
Contractile effect of acetylcholine on isolated ampullar segment of Fallopian tubes.
Topics: Acetylcholine; Adult; Aged; Diamines; Fallopian Tubes; Female; Follicular Phase; Humans; Lidocaine; Luteal Phase; Mecamylamine; Menopause; Middle Aged; Muscle Contraction; Muscle, Smooth; Nifedipine; Piperidines; Pirenzepine; Verapamil | 2004 |
Aging-related alterations in the contractile responses to acetylcholine, muscarinic cholinoceptors and cholinesterase activities in jejunum and colon of the male Fischer 344 rats.
Topics: Acetylcholine; Aging; Animals; Atropine; Cholinesterases; Colon; Diamines; Dose-Response Relationship, Drug; Gastrointestinal Motility; In Vitro Techniques; Intestine, Large; Jejunum; Male; Muscarinic Antagonists; Muscle, Smooth; Piperidines; Pirenzepine; Rats; Rats, Inbred F344 | 2004 |
Muscarinic M2 receptor stimulation of Cav1.2b requires phosphatidylinositol 3-kinase, protein kinase C, and c-Src.
Topics: Acetylcholine; Animals; Barium; Calcium Channels, L-Type; Carbazoles; Cells, Cultured; Chromones; Class Ib Phosphatidylinositol 3-Kinase; Diamines; Enzyme Inhibitors; GTP-Binding Protein beta Subunits; GTP-Binding Protein gamma Subunits; Indoles; Ion Channel Gating; Ion Transport; Isoenzymes; Male; Morpholines; Muscarinic Agonists; Muscarinic Antagonists; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Naphthalenes; Patch-Clamp Techniques; Phorbol 12,13-Dibutyrate; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Piperidines; Portal Vein; Protein Kinase C; Proto-Oncogene Proteins pp60(c-src); Pyrimidines; Rabbits; Receptor, Muscarinic M2; Receptor, Muscarinic M3; Signal Transduction | 2004 |
Contractile effect of acetylcholine on isolated isthmic segment of fallopian tubes.
Topics: Acetylcholine; Adult; Aged; Atropine; Diamines; Dose-Response Relationship, Drug; Fallopian Tubes; Female; Follicular Phase; Humans; Lidocaine; Luteal Phase; Mecamylamine; Middle Aged; Muscle Contraction; Muscle, Smooth; Nifedipine; Piperidines; Pirenzepine; Postmenopause; Receptors, Muscarinic | 2004 |
Effect of M2 muscarinic receptor blockade in rats with haloperidol-produced catatonic syndrome.
Topics: Animals; Catalepsy; Cyclopentanes; Diamines; Dopamine; Haloperidol; Male; Mandelic Acids; Muscarinic Antagonists; Piperidines; Receptor, Muscarinic M2; Syndrome; Trihexyphenidyl | 2004 |
Intrathecal clonidine inhibits mechanical allodynia via activation of the spinal muscarinic M1 receptor in streptozotocin-induced diabetic mice.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Analgesics; Animals; Atropine; Blood Glucose; Clonidine; Diabetes Mellitus, Experimental; Diamines; Injections, Spinal; Male; Mice; Motor Activity; Muscarinic Agonists; Muscarinic Antagonists; Pain; Pain Threshold; Piperidines; Pirenzepine; Receptor, Muscarinic M1; Receptor, Muscarinic M2; Receptor, Muscarinic M3; Spinal Cord; Streptozocin; Stress, Mechanical; Time Factors | 2004 |
Postjunctional modulation by muscarinic M2 receptors of responses to electrical field stimulation of rat detrusor muscle preparations.
Topics: Animals; Diamines; Electric Stimulation; In Vitro Techniques; Muscarinic Antagonists; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Parasympatholytics; Piperidines; Propranolol; Rats; Rats, Sprague-Dawley; Receptor, Muscarinic M2; Theophylline; Time Factors; Urinary Bladder; Vasodilator Agents | 2005 |
M(2) and M(3) muscarinic receptor-mediated contractions in longitudinal smooth muscle of the ileum studied with receptor knockout mice.
Topics: Animals; Calcium Channel Blockers; Carbachol; Cholinergic Agonists; Diamines; Female; Ileum; In Vitro Techniques; Male; Mice; Mice, Knockout; Muscarinic Antagonists; Muscle Contraction; Muscle, Smooth; Nicardipine; Pertussis Toxin; Piperidines; Receptor, Muscarinic M2; Receptor, Muscarinic M3 | 2005 |
Spinal muscarinic and nicotinic subtypes activated by clonidine in postincisional pain.
Topics: Aconitine; Adrenergic alpha-Agonists; Animals; Behavior, Animal; Clonidine; Diamines; Dihydro-beta-Erythroidine; Injections, Spinal; Male; Muscarinic Agonists; Nicotinic Agonists; Pain; Piperidines; Rats; Rats, Sprague-Dawley; Receptor, Muscarinic M1; Receptor, Muscarinic M2; Receptors, Muscarinic; Receptors, Nicotinic; Spine | 2005 |
Pharmacological characterization of muscarinic receptor subtypes mediating vasoconstriction of human umbilical vein.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Acetylcholine; Atropine; Diamines; Humans; In Vitro Techniques; Piperidines; Pirenzepine; Receptors, Muscarinic; Umbilical Veins; Vasoconstriction | 2006 |
Characterization of muscarinic receptor-mediated cationic currents in longitudinal smooth muscle cells of mouse small intestine.
Topics: Animals; Carbachol; Cations; Cholinergic Agonists; Diamines; Dose-Response Relationship, Drug; Enzyme Inhibitors; Estrenes; Guinea Pigs; In Vitro Techniques; Intestine, Small; Ion Channel Gating; Ion Channels; Male; Membrane Potentials; Mice; Muscarinic Antagonists; Myocytes, Smooth Muscle; Pertussis Toxin; Piperidines; Pyrrolidinones; Receptor, Muscarinic M2; Receptor, Muscarinic M3; Type C Phospholipases | 2006 |
Muscarinic regulation of neonatal rat bladder spontaneous contractions.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Animals, Newborn; Calcium Channel Agonists; Carbachol; Cholinergic Agonists; Cholinesterase Inhibitors; Diamines; Electric Stimulation; Muscle Contraction; Muscle Hypertonia; Muscle, Smooth; Parasympatholytics; Peptides; Physostigmine; Piperidines; Pirenzepine; Rats; Rats, Sprague-Dawley; Receptor, Muscarinic M2; Receptor, Muscarinic M3; Urinary Bladder | 2006 |
Human idiopathic and neurogenic overactive bladders and the role of M2 muscarinic receptors in contraction.
Topics: Adult; Aged; Benzofurans; Carbachol; Diamines; Dose-Response Relationship, Drug; Female; Humans; In Vitro Techniques; Male; Middle Aged; Muscle Contraction; Muscle, Smooth; Piperidines; Pirenzepine; Pyrrolidines; Receptors, Muscarinic; Urinary Bladder; Urinary Bladder, Neurogenic; Urinary Bladder, Overactive | 2007 |
In vitro characterization of parasympathetic and sympathetic responses in cyclophosphamide-induced cystitis in the rat.
Topics: Adenosine Triphosphate; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Cyclophosphamide; Cystitis; Diamines; Electric Stimulation; In Vitro Techniques; Male; Muscarinic Antagonists; Muscle Contraction; Parasympatholytics; Phentolamine; Piperidines; Pirenzepine; Propranolol; Purinergic P2 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Suramin; Sympatholytics; Urinary Bladder | 2007 |
Aging-induced decrease of cholinergic response and calcium sensitivity on rat jejunum contractions.
Topics: Adrenergic Agonists; Aging; Animals; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Signaling; Diamines; Isradipine; Jejunum; Male; Methacholine Chloride; Muscarinic Agonists; Muscarinic Antagonists; Peristalsis; Piperidines; Pirenzepine; Rats; Rats, Wistar; Receptor, Muscarinic M1; Receptor, Muscarinic M2; Receptor, Muscarinic M3; Receptors, Adrenergic, alpha; Receptors, Muscarinic | 2007 |
Roles of muscarinic receptor subtypes in small intestinal motor dysfunction in acute radiation enteritis.
Topics: Animals; Diamines; Enteritis; Gastrointestinal Motility; Ileum; Male; Manometry; Piperidines; Pirenzepine; Radiation Injuries, Experimental; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic | 2007 |
Functional expression of M3, a muscarinic acetylcholine receptor subtype, in taste bud cells of mouse fungiform papillae.
Topics: Acetylcholine; Animals; Atropine; Calcium Signaling; Cells, Cultured; Diamines; Electrophysiology; Gene Expression; Inositol 1,4,5-Trisphosphate Receptors; Mice; Mice, Inbred Strains; Muscarinic Antagonists; Patch-Clamp Techniques; Phospholipase C beta; Piperidines; Pirenzepine; Receptor, Muscarinic M3; Receptors, Muscarinic; Reverse Transcriptase Polymerase Chain Reaction; Synaptosomal-Associated Protein 25; Taste Buds; Tropicamide; Vesicular Acetylcholine Transport Proteins | 2008 |
Subtype-selective blockade of cardiac muscarinic receptors inhibits vagal chronotropic responses in cats.
Topics: Animals; Cats; Diamines; Electrocardiography; Female; Gallamine Triethiodide; Heart; Heart Rate; Male; Muscarinic Antagonists; Nicotinic Antagonists; Parasympatholytics; Piperidines; Pirenzepine; Receptor, Muscarinic M1; Receptor, Muscarinic M2; Receptor, Muscarinic M3; Receptors, Muscarinic; Vagus Nerve | 2008 |
Changes in muscarinic receptors in the toad urothelial cell line TBM-54 following acrolein treatment.
Topics: Acrolein; Animals; Blotting, Western; Bufo marinus; Carbachol; Cell Line; Diamines; Dose-Response Relationship, Drug; Extracellular Fluid; Hydrogen-Ion Concentration; Muscarinic Agonists; Muscarinic Antagonists; Piperidines; Pirenzepine; Receptors, Muscarinic; Urinary Bladder; Urothelium | 2008 |
Bronchodilatory effects of S-isopetasin, an antimuscarinic sesquiterpene of Petasites formosanus, on obstructive airway hyperresponsiveness.
Topics: Acetylcholine; Animals; Atropine; Binding, Competitive; Bronchial Hyperreactivity; Bronchoconstrictor Agents; Bronchodilator Agents; Cells, Cultured; Cholinesterase Inhibitors; Diamines; Dose-Response Relationship, Drug; Guinea Pigs; Humans; Ipratropium; Male; Muscarinic Antagonists; Muscle, Smooth; N-Methylscopolamine; Neostigmine; Petasites; Piperidines; Protein Binding; Receptor, Muscarinic M3; Sesquiterpenes; Time Factors; Trachea | 2008 |
Muscarinic receptors involved in airway vascular leakage induced by experimental gastro-oesophageal reflux.
Topics: Animals; Atropine; Capillary Permeability; Diamines; Female; Ganglionic Blockers; Gastroesophageal Reflux; Guinea Pigs; Hexamethonium; In Vitro Techniques; Male; Muscarinic Antagonists; Nicotinic Antagonists; Parasympatholytics; Piperidines; Pirenzepine; Receptor, Muscarinic M1; Receptor, Muscarinic M2; Receptor, Muscarinic M4; Receptors, Muscarinic; Receptors, Nicotinic; Regional Blood Flow; Respiratory System | 2008 |
Refractoriness of the sheep superior vena cava myocardial sleeve.
Topics: Acetylcholine; Animals; Carbachol; Cholinergic Agonists; Diamines; Electrophysiologic Techniques, Cardiac; In Vitro Techniques; Microelectrodes; Muscarinic Antagonists; Myocardium; Myocytes, Cardiac; Piperidines; Refractometry; Sheep; Tropicamide; Vasodilator Agents; Vena Cava, Superior | 2008 |
Central muscarinic receptor subtypes involved in pilocarpine-induced salivation, hypertension and water intake.
Topics: Animals; Blood Pressure; Diamines; Drinking Behavior; Heart Rate; Hypertension; Injections, Intraventricular; Male; Muscarinic Antagonists; Pilocarpine; Piperidines; Pirenzepine; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic; Saliva; Tropicamide | 2008 |
Functional characterization of the muscarinic receptors involved in endothelium-dependent relaxation in isolated canine uterine artery.
Topics: Acetylcholine; Animals; Arteries; Atropine; Cholinergic Agents; Diamines; Dogs; Endothelium, Vascular; Female; Hysterectomy; In Vitro Techniques; Muscarinic Antagonists; Parasympatholytics; Piperidines; Pirenzepine; Receptors, Muscarinic; Uterus | 2009 |
Spinal cholinergic mechanism of the relieving effects of electroacupuncture on cold and warm allodynia in a rat model of neuropathic pain.
Topics: Animals; Atropine; Cholinergic Agents; Cholinergic Fibers; Cold Temperature; Diamines; Disease Models, Animal; Electroacupuncture; Hot Temperature; Hyperesthesia; Male; Mecamylamine; Neuralgia; Pain Threshold; Piperidines; Pirenzepine; Rats; Rats, Sprague-Dawley; Receptor, Muscarinic M1; Spinal Nerves | 2009 |
Muscarinic receptor antagonism at the spinal cord level causes inhibitory effects on male rat sexual behavior.
Topics: Animals; Diamines; Injections, Spinal; Male; Muscarinic Antagonists; Piperidines; Rats; Rats, Wistar; Rotarod Performance Test; Sexual Behavior, Animal; Spinal Cord; Tropicamide | 2009 |
Carbachol regulates pacemaker activities in cultured interstitial cells of Cajal from the mouse small intestine.
Topics: Animals; Anti-Inflammatory Agents; Biological Clocks; Calcium; Calcium-Transporting ATPases; Carbachol; Cation Transport Proteins; Cells, Cultured; Diamines; Flufenamic Acid; Guanosine Diphosphate; Intestine, Small; Membrane Potentials; Mice; Mice, Inbred BALB C; Neuromuscular Depolarizing Agents; Patch-Clamp Techniques; Piperidines; Plant Roots; Receptor, Muscarinic M2; Receptor, Muscarinic M3; Thapsia; Thapsigargin; Thionucleotides | 2009 |
An increase in intracelluar free calcium ions modulated by cholinergic receptors in rat facial nucleus.
Topics: Acetylcholine; Aniline Compounds; Animals; Brain Stem; Calcium; Diamines; Facial Nerve; Female; Fluorescent Dyes; In Vitro Techniques; Male; Microscopy, Confocal; Motor Neurons; Muscarinic Agonists; Nicotine; Nicotinic Agonists; Piperidines; Pirenzepine; Rats; Rats, Sprague-Dawley; Receptors, Cholinergic; Receptors, Muscarinic; Receptors, Nicotinic; Tropicamide; Xanthenes | 2009 |
M₃muscarinic receptors mediate acetylcholine-induced pulmonary vasodilation in pulmonary hypertension.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acetylcholine; Animals; Diamines; Hypertension, Pulmonary; Lung; Piperidines; Pirenzepine; Rabbits; Receptor, Muscarinic M3; Vasodilation | 2010 |
Urothelial/lamina propria spontaneous activity and the role of M3 muscarinic receptors in mediating rate responses to stretch and carbachol.
Topics: Animals; Atropine; Benzhydryl Compounds; Benzofurans; Carbachol; Cresols; Diamines; Mandelic Acids; Mucous Membrane; Muscarinic Antagonists; Muscle Contraction; Phenylpropanolamine; Piperidines; Pirenzepine; Pyrrolidines; Quinuclidines; Receptor, Muscarinic M3; Solifenacin Succinate; Stress, Mechanical; Swine; Tetrahydroisoquinolines; Tolterodine Tartrate; Urinary Bladder; Urothelium | 2011 |
Functional M3 cholinoreceptors are present in pacemaker and working myocardium of murine heart.
Topics: Action Potentials; Animals; Diamines; Male; Mice; Muscarinic Agonists; Muscarinic Antagonists; Myocardium; Pilocarpine; Piperidines; Pirenzepine; Receptor, Muscarinic M1; Receptor, Muscarinic M2; Receptor, Muscarinic M3; Sinoatrial Node | 2012 |
Inhibition of stretching-evoked ATP release from bladder mucosa by anticholinergic agents.
Topics: Adenosine Triphosphate; Animals; Biomechanical Phenomena; Diamines; Guinea Pigs; In Vitro Techniques; Male; Mucous Membrane; Muscarinic Antagonists; Piperidines; Urinary Bladder; Urothelium | 2012 |
Effect of selective stimulation of muscarinic M3 cholinoceptors on electrical and contractile activity of rat ventricular myocardium.
Topics: Action Potentials; Animals; Diamines; Heart; Muscarinic Agonists; Muscarinic Antagonists; Myocardial Contraction; Myocardium; Parasympatholytics; Pilocarpine; Piperidines; Rats; Receptor, Muscarinic M2; Receptor, Muscarinic M3; Ventricular Function | 2013 |
Activation of muscarinic M3 receptors inhibits large-conductance voltage- and Ca2+-activated K+ channels in rat urinary bladder smooth muscle cells.
Topics: Amphotericin B; Animals; Carbachol; Cholinergic Agonists; Diamines; Evoked Potentials; Gene Expression Regulation; Large-Conductance Calcium-Activated Potassium Channels; Male; Membrane Potentials; Muscarinic Antagonists; Myocytes, Smooth Muscle; Patch-Clamp Techniques; Piperidines; Rats; Rats, Sprague-Dawley; Receptor, Muscarinic M3; Urinary Bladder | 2013 |
The inhibitory effects of antimuscarinic autoantibodies in the sera of primary Sjogren syndrome patients on the gastrointestinal motility.
Topics: Animals; Autoantibodies; Carbachol; Cholinergic Agonists; Colon; Diamines; Dose-Response Relationship, Drug; Gastrointestinal Motility; Humans; In Vitro Techniques; Male; Mice; Mice, Inbred BALB C; Muscarinic Antagonists; Muscle Contraction; Muscle, Smooth; Piperidines; Receptor, Muscarinic M2; Receptor, Muscarinic M3; Sjogren's Syndrome; Stomach | 2013 |
Pharmacological characterization of muscarinic receptors in the contractions of isolated bronchi in the horse.
Topics: Animals; Bronchi; Bronchial Spasm; Diamines; Gene Expression Regulation; Horses; Male; Parasympatholytics; Piperidines; Receptor, Muscarinic M1; Receptor, Muscarinic M2; Receptor, Muscarinic M3; Sulfonamides; Thiadiazoles | 2014 |
Expression and function of muscarinic subtype receptors in bladder interstitial cells of cajal in rats.
Topics: Action Potentials; Animals; Atropine; Calcium Channels; Carbachol; Cholinergic Agonists; Diamines; Interstitial Cells of Cajal; Male; Muscarinic Antagonists; Patch-Clamp Techniques; Piperidines; Rats; Rats, Sprague-Dawley; Receptor, Muscarinic M2; Receptor, Muscarinic M3; Urinary Bladder | 2014 |
Different Myocardial Sensitivity in Newborn and Mature Rats to Selective Stimulation of M3 Cholinoreceptors.
Topics: Action Potentials; Age Factors; Animals; Animals, Newborn; Diamines; Heart Atria; Heart Ventricles; Male; Muscarinic Agonists; Muscarinic Antagonists; Pilocarpine; Piperidines; Rats; Receptor, Muscarinic M2; Receptor, Muscarinic M3 | 2015 |
Effects of Dangkwisoo‑san, a traditional herbal medicine for treating pain and blood stagnation, on the pacemaker activities of cultured interstitial cells of Cajal.
Topics: Animals; Calcium-Transporting ATPases; Cells, Cultured; Diamines; Female; Gastrointestinal Motility; Guanosine Diphosphate; Interstitial Cells of Cajal; Intestine, Small; Male; Mice; Mice, Inbred BALB C; Pain; Phytotherapy; Piperidines; Plants, Medicinal; Receptor, Muscarinic M2; Receptor, Muscarinic M3; Thapsigargin; Thionucleotides | 2015 |
Balanced cholinergic modulation of spinal locomotor circuits via M2 and M3 muscarinic receptors.
Topics: Acetylcholine; Action Potentials; Animals; Animals, Newborn; Diamines; In Vitro Techniques; Locomotion; Mice; Mice, Inbred C57BL; Motor Neurons; Muscarine; Piperidines; Receptor, Muscarinic M2; Receptor, Muscarinic M3; Spinal Cord | 2019 |