methoctramine has been researched along with carbachol in 74 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (8.11) | 18.7374 |
| 1990's | 33 (44.59) | 18.2507 |
| 2000's | 27 (36.49) | 29.6817 |
| 2010's | 8 (10.81) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Sastry, BV; Stephan, CC | 1 |
| Lau, WM; Szilagyi, M | 1 |
| Martin, JR | 1 |
| Cost, M; Majewski, H | 1 |
| Budriesi, R; Chiarini, A; Melchiorre, C; Minarini, A; Tumiatti, V | 1 |
| Costa, G; Massi, M; Melchiorre, C; Perfumi, M; Polidori, C; Sajia, A | 1 |
| Yang, CM | 1 |
| Massi, M; Melchiorre, C; Perfumi, M; Polidori, C; Pompei, PL | 1 |
| Fischofer-Hahn, C; McLeskey, SW; Takahashi, K; Wojcik, WJ | 1 |
| Bagetta, G; Constanti, A | 1 |
| el-Fakahany, EE; Forray, C; Lee, NH | 1 |
| Massi, M; Melchiorre, C; Polidori, C | 1 |
| Delmendo, R; Michel, AD; Stefanich, E; Whiting, RL | 1 |
| Cornett, CM; Eglen, RM; Kunysz, EA; Michel, AD; Whiting, RL | 1 |
| Angeli, P; Brasili, L; Giardinà, D; Melchiorre, C; Picchio, MT; Quaglia, W | 1 |
| Angeli, P; Lambrecht, G; Melchiorre, C; Mutschler, E; Picchio, MT; Wess, J | 1 |
| Hackmiller, RC; Jumblatt, JE | 1 |
| Imaizumi, Y; Kawai, T; Masuda, Y; Ryang, S; Tanaka, M; Watanabe, M; Yamahara, NS | 1 |
| Bolognesi, ML; Budriesi, R; Chiarini, A; Melchiorre, C; Minarini, A | 1 |
| Birmingham, AT; Harriss, DR; Hill, SJ; Marsh, KA | 1 |
| Ko, FN; Lin, CH; Teng, CM; Wu, YC; Yang, CM | 1 |
| Almazan, G; Cohen, RI | 1 |
| Iwamoto, ET; Marion, L | 1 |
| Costa, E; de Erausquin, G; Fohrman, EB; Wojcik, WJ | 1 |
| De Klippel, N; Ebinger, G; Michotte, Y; Sarre, S | 1 |
| Angeli, P; Bianchi, S; Imeri, L; Mancia, M | 1 |
| Datta, S; Hobson, JA; Quattrochi, JJ | 1 |
| Sjögren, C; Tobin, G | 1 |
| Latifpour, J; Mutoh, S; Saito, M; Weiss, RM | 1 |
| Levin, RJ; Przyborski, SA | 1 |
| Semba, K; White, TD | 1 |
| Aslan, N; Gören, Z; Oktay, S; Onat, F | 1 |
| Baba, H; Goldstein, PA; Kohno, T; Okamoto, M; Shimoji, K; Yoshimura, M | 1 |
| Cobuzzi, A; Lai, FM; Spinelli, W | 1 |
| Kawana, S; Miyamoto, A; Namiki, A; Ohshika, H; Yamamoto, S | 1 |
| Braverman, A; Legos, J; Luthin, G; Ruggieri, M; Young, W | 1 |
| Haapalinna, A; Larson, J; Niittykoski, M; Ruotsalainen, S; Sirviö, J | 1 |
| Bernardi, G; Bonci, A; Grillner, P; Mercuri, NB; Svensson, TH | 1 |
| Chitravanshi, VC; Sapru, HN | 1 |
| Levendusky, M; Longhurst, PA | 1 |
| Chapple, CR; Chess-Williams, R; Yamanishi, T; Yasuda, K | 1 |
| Daniels, DV; Eglen, RM; Ford, AP; Hegde, SS; Meloy, TD | 1 |
| Dohi, S; Ishizawa, Y; Ma, HC; Wang, YF; Yanagidate, F | 1 |
| Kadota, H; Kuwahara, M; Mikami, H; Nishibata, R; Tsubone, H | 1 |
| Choritz, L; Hildebrandt, J; Strauss, O; Thieme, H; Wiederholt, M | 1 |
| Choppin, A; Eglen, RM | 1 |
| Alzheimer, C; Seeger, T | 1 |
| Herzog, M; Liu, J; Scherer, EQ; Scofield, MA; Shimozono, M; Wangemann, P | 1 |
| Delbro, DS; Giglio, D; Tobin, G | 1 |
| Goodhead, LH; Mitchell, SN; Moss, S; Sharott, A | 1 |
| Gomeza, J; Klebroff, W; Trendelenburg, AU; Wess, J; Zhou, H | 1 |
| Bukharaeva, EA; Magazanik, LG; Nikolsky, EE; Samigullin, D; Vyskocil, F | 1 |
| Freund, TF; Hájos, N; Pálhalmi, J; Paulsen, O | 1 |
| Chen, HZ; Cui, XL; Wu, BW; Wu, DM | 1 |
| Izumi, Y; Komori, S; Matsuyama, H; Okamoto, H; Sakamoto, T; Uchiyama, M; Unno, T; Wess, J; Yamada, M | 1 |
| Avellar, MC; Maróstica, E; Porto, CS; Siu, ER; Yasuhara, F | 1 |
| Cabadak, H; Kan, B | 1 |
| Hattori, M; Komori, S; Matsuyama, H; Nishimura, M; Sakamoto, T; Uchiyama, M; Unno, T | 1 |
| de Groat, WC; Ng, YK; Wu, HY | 1 |
| Braverman, AS; Lebed, B; Linder, M; Ruggieri, MR | 1 |
| Chapple, CR; Chess-Williams, R; Stevens, LA | 1 |
| Andersson, M; Aronsson, P; Delbro, DS; Giglio, D; Haraldsson, B; Tobin, G | 1 |
| Chen, H; Chen, YH; Li, J; Li, L; Liang, L; Liu, X; Liu, Y; Ma, J; Peng, L; Qi, J; Wu, X; Xiao, J; Xu, J; Yang, Y; Zhang, Y; Zhao, C | 1 |
| Luo, L; Luo, Y; Ruan, DY; Tang, M; Wang, H; Wang, M; Zhu, D | 1 |
| Choi, S; Choi, SJ; Jun, JY; Kim, SH; Parajuli, SP; So, KY; Sohn, HM; Yeum, CH; Yoon, PJ | 1 |
| Braverman, AS; Khayyam, U; Miller, LS; Ruggieri, MR; Tallarida, RJ; Tiwana, MI; Vegesna, AK | 1 |
| Amari, G; Bassani, F; Battipaglia, L; Bergamaschi, M; Berti, F; Bolzoni, PT; Cacciani, F; Cenacchi, V; Civelli, M; Delcanale, M; Geppetti, PA; Harrison, S; Mannini, F; Pastore, F; Patacchini, R; Petrillo, P; Razzetti, R; Rizzi, A; Rossoni, G; Santoro, E; Scudellaro, R; Villetti, G; Volta, R; Zaniboni, M | 1 |
| Jragh, DM; Khan, I; Oriowo, MA | 1 |
| Chess-Williams, R; Moro, C; Uchiyama, J | 1 |
| Chapman, CA; Glasgow, SD | 1 |
| Parajuli, SP; Petkov, GV | 1 |
| Jackson, MW; Park, K; Park, S | 1 |
| Deng, J; Li, L; Shi, C; Song, B; Wu, Y; Zhang, X | 1 |
74 other study(ies) available for methoctramine and carbachol
| Article | Year |
|---|---|
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
Characterization of the subtype of muscarinic receptor coupled to the stimulation of phosphoinositide hydrolysis in 132-1N1 human astrocytoma cells.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Astrocytoma; Atropine; Carbachol; Diamines; Humans; Hydrolysis; Parasympathomimetics; Phosphatidylinositols; Piperidines; Pirenzepine; Receptors, Muscarinic; Scopolamine; Tumor Cells, Cultured | 1992 |
A pharmacological profile of glycopyrrolate: interactions at the muscarinic acetylcholine receptor.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Acetylcholine; Animals; Binding, Competitive; Carbachol; Diamines; Female; Gallamine Triethiodide; Glycopyrrolate; Guinea Pigs; In Vitro Techniques; Ligands; Muscarinic Antagonists; Myocardial Contraction; Parasympatholytics; Pirenzepine; Quinuclidinyl Benzilate | 1992 |
Pressor response to posterior hypothalamic administration of carbachol is mediated by muscarinic M3 receptor.
Topics: Animals; Atropine Derivatives; Blood Pressure; Carbachol; Diamines; Dose-Response Relationship, Drug; Hypothalamus, Posterior; Kinetics; Male; Microinjections; Muscarinic Antagonists; Parasympatholytics; Piperidines; Pirenzepine; Rats; Rats, Inbred Strains; Receptors, Muscarinic | 1992 |
Evidence for facilitatory and inhibitory muscarinic receptors on postganglionic sympathetic nerves in mouse isolated atria.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Animals; Atropine; Carbachol; Cocaine; Diamines; Dicyclomine; Female; Heart; Hexamethonium Compounds; In Vitro Techniques; Mice; Myocardium; Nerve Endings; Neurons; Norepinephrine; Parasympatholytics; Pirenzepine; Receptors, Muscarinic; Sympathetic Nervous System; Synaptic Transmission | 1991 |
Further investigation on methoctramine-related tetraamines: effects of terminal N-substitution and of chain length separating the four nitrogens on M2 muscarinic receptor blocking activity.
Topics: Animals; Carbachol; Diamines; Electric Stimulation; Female; Guinea Pigs; Heart; Heart Atria; Ileum; In Vitro Techniques; Magnetic Resonance Spectroscopy; Male; Muscarinic Antagonists; Muscle, Smooth; Parasympatholytics; Spectrophotometry, Infrared | 1991 |
The release of atrial natriuretic factor induced by central carbachol injection may be mediated by muscarinic M1 receptors.
Topics: Animals; Atrial Natriuretic Factor; Brain; Carbachol; Diamines; Dose-Response Relationship, Drug; Injections, Intraventricular; Injections, Subcutaneous; Male; Parasympatholytics; Piperidines; Pirenzepine; Rats; Rats, Inbred Strains; Receptors, Muscarinic | 1991 |
Characterization of muscarinic receptors in dog tracheal smooth muscle cells.
Topics: Animals; Atropine; Carbachol; Diamines; Dogs; In Vitro Techniques; Kinetics; Muscle, Smooth; N-Methylscopolamine; Parasympatholytics; Piperidines; Pirenzepine; Receptors, Muscarinic; Scopolamine Derivatives; Trachea | 1991 |
Natriuresis, kaliuresis and antidiuresis induced by central carbachol injection are mediated by muscarinic M1 receptors.
Topics: Animals; Carbachol; Diamines; Diuresis; Dose-Response Relationship, Drug; Injections, Intraventricular; Male; Muscarinic Antagonists; Natriuresis; Piperidines; Potassium; Rats; Rats, Inbred Strains; Receptors, Muscarinic | 1991 |
Specificity of methoctramine in blocking muscarinic receptors which inhibit adenylate cyclase in cerebellar granule cells.
Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Carbachol; Cells, Cultured; Cerebellum; Diamines; Hydrolysis; Parasympatholytics; Phosphatidylinositols; Pirenzepine; Quinuclidinyl Benzilate; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Synaptosomes | 1990 |
Muscarinic suppression of the evoked N-wave by oxotremorine-M recorded in the guinea-pig olfactory cortex slice.
Topics: Action Potentials; Animals; Carbachol; Cerebral Cortex; Diamines; Electric Stimulation; Electroencephalography; Evoked Potentials; Guinea Pigs; In Vitro Techniques; Olfactory Bulb; Oxotremorine; Parasympatholytics; Parasympathomimetics; Pirenzepine; Receptors, Muscarinic | 1990 |
Methoctramine, a cardioselective muscarinic antagonist, stimulates phosphoinositide hydrolysis in rat cerebral cortex.
Topics: Animals; Atropine; Carbachol; Cerebral Cortex; Diamines; Hydrolysis; In Vitro Techniques; Male; Parasympatholytics; Phosphatidylinositols; Rats; Rats, Inbred Strains | 1989 |
Methoctramine, a selective M2 alpha muscarinic receptor antagonist, does not inhibit carbachol-induced drinking in the rat.
Topics: Angiotensin II; Animals; Carbachol; Diamines; Dose-Response Relationship, Drug; Drinking; Injections, Intraventricular; Male; Parasympatholytics; Rats; Rats, Inbred Strains | 1989 |
Binding characteristics of the muscarinic receptor subtype of the NG108-15 cell line.
Topics: Animals; Carbachol; Cell Membrane; Cerebral Cortex; Diamines; Humans; Myocardium; Pirenzepine; Rats; Receptors, Muscarinic; Submandibular Gland; Tumor Cells, Cultured; Virulence Factors, Bordetella | 1989 |
The interaction of hexamethonium with muscarinic receptor subtypes in vitro.
Topics: Animals; Carbachol; Diamines; Guinea Pigs; Hexamethonium Compounds; In Vitro Techniques; Kinetics; Muscle Contraction; Muscle, Smooth, Vascular; Myocardium; N-Methylscopolamine; Pirenzepine; Potassium Chloride; Receptors, Muscarinic; Scopolamine Derivatives; Submandibular Gland | 1989 |
Structure-activity relationships among methoctramine-related polymethylene tetraamines. Chain-length and substituent effects on M-2 muscarinic receptor blocking activity.
Topics: Animals; Carbachol; Chemical Phenomena; Chemistry; Diamines; Guinea Pigs; In Vitro Techniques; Male; Parasympatholytics; Polyamines; Rats; Receptors, Muscarinic; Structure-Activity Relationship | 1989 |
Antimuscarinic action of methoctramine, a new cardioselective M-2 muscarinic receptor antagonist, alone and in combination with atropine and gallamine.
Topics: Animals; Atropine; Carbachol; Diamines; Drug Interactions; Gallamine Triethiodide; Guinea Pigs; Heart Atria; Ileum; In Vitro Techniques; Muscle Contraction; Myocardial Contraction; Rats; Receptors, Muscarinic | 1987 |
M2-type muscarinic receptors mediate prejunctional inhibition of norepinephrine release in the human iris-ciliary body.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Carbachol; Child; Ciliary Body; Diamines; Dose-Response Relationship, Drug; Electric Stimulation; Humans; In Vitro Techniques; Iris; Middle Aged; Muscarine; Norepinephrine; Pilocarpine; Piperidines; Pirenzepine; Receptors, Muscarinic | 1994 |
Characterization of muscarinic receptors mediating relaxation and contraction in the rat iris dilator muscle.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Acetylcholine; Alkaloids; Animals; Arecoline; Bethanechol; Carbachol; Diamines; Dose-Response Relationship, Drug; Furans; Ganglia, Parasympathetic; Ganglionectomy; Iris; Male; Methacholine Chloride; Muscarinic Agonists; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Naphthalenes; Parasympatholytics; Pilocarpine; Piperidines; Pirenzepine; Rats; Rats, Wistar; Receptors, Muscarinic | 1995 |
In vitro characterization of tripitramine, a polymethylene tetraamine displaying high selectivity and affinity for muscarinic M2 receptors.
Topics: Animals; Benzodiazepines; Carbachol; Diamines; Dose-Response Relationship, Drug; Duodenum; Guinea Pigs; Heart Atria; Ileum; In Vitro Techniques; Lung; Male; Muscarinic Antagonists; Rats; Receptors, Muscarinic; Trachea; Vas Deferens | 1995 |
Expression of muscarinic M3-receptors coupled to inositol phospholipid hydrolysis in human detrusor cultured smooth muscle cells.
Topics: Carbachol; Cells, Cultured; Diamines; Humans; Hydrolysis; Inositol Phosphates; Methacholine Chloride; Muscarinic Agonists; Muscle, Smooth; Oxotremorine; Phosphatidylinositols; Pilocarpine; Pirenzepine; Receptors, Muscarinic; Urinary Bladder | 1995 |
Antimuscarinic action of liriodenine, isolated from Fissistigma glaucescens, in canine tracheal smooth muscle.
Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Antineoplastic Agents, Phytogenic; Aporphines; Binding, Competitive; Carbachol; Cells, Cultured; Cyclic AMP; Diamines; Dogs; Female; Hydrolysis; Inositol Phosphates; Male; Muscarinic Antagonists; Muscle Contraction; Muscle, Smooth; Parasympatholytics; Phosphatidylinositols; Piperidines; Plants, Medicinal; Receptors, Muscarinic; Trachea | 1994 |
Rat oligodendrocytes express muscarinic receptors coupled to phosphoinositide hydrolysis and adenylyl cyclase.
Topics: Adenylyl Cyclases; Animals; Carbachol; Cells, Cultured; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Diamines; Hydrolysis; Isoproterenol; Nerve Tissue Proteins; Oligodendroglia; Phosphatidylinositols; Pirenzepine; Polymerase Chain Reaction; Rats; Receptors, Muscarinic; Signal Transduction; Tetradecanoylphorbol Acetate | 1994 |
Characterization of the antinociception produced by intrathecally administered muscarinic agonists in rats.
Topics: Adrenergic alpha-Antagonists; Analgesia; Animals; Carbachol; Diamines; Dioxolanes; Dose-Response Relationship, Drug; Drug Interactions; Injections, Spinal; Male; Mecamylamine; Muscarine; Narcotic Antagonists; Nociceptors; Pain Measurement; Parasympathomimetics; Pirenzepine; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha; Receptors, Muscarinic; Receptors, Serotonin; Spinal Cord; Time Factors; Tissue Distribution | 1993 |
Muscarinic m3 receptors and dynamics of intracellular Ca2+ cerebellar granule neurons.
Topics: Animals; Calcium; Carbachol; Cells, Cultured; Cerebellum; Dantrolene; Diamines; Fura-2; Glutamates; Glutamic Acid; Microscopy, Fluorescence; Neurons; Parasympatholytics; Quinuclidines; Rats; Receptors, Glutamate; Receptors, Muscarinic; Terpenes; Thapsigargin; Xanthenes | 1993 |
Effect of M1- and M2-muscarinic drugs on striatal dopamine release and metabolism: an in vivo microdialysis study comparing normal and 6-hydroxydopamine-lesioned rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Atropine; Carbachol; Corpus Striatum; Diamines; Dopamine; Homovanillic Acid; Male; Microdialysis; Oxidopamine; Pirenzepine; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic; Reference Values | 1993 |
Selective blockade of different brain stem muscarinic receptor subtypes: effects on the sleep-wake cycle.
Topics: Animals; Brain Stem; Carbachol; Diamines; Electroencephalography; Male; Microinjections; Muscarinic Antagonists; Parasympatholytics; Piperidines; Pirenzepine; Polysomnography; Rats; Reticular Formation; Sleep; Wakefulness | 1994 |
Effect of specific muscarinic M2 receptor antagonist on carbachol induced long-term REM sleep.
Topics: Animals; Carbachol; Cats; Diamines; Electroencephalography; Male; Microinjections; Parasympatholytics; Receptors, Muscarinic; Sleep, REM; Time Factors | 1993 |
In vivo and in vitro effects of muscarinic receptor antagonists on contractions and release of [3H]acetylcholine in the rabbit urinary bladder.
Topics: Acetylcholine; Animals; Carbachol; Diamines; Female; Gallamine Triethiodide; Muscarinic Antagonists; Muscle Contraction; Parasympatholytics; Piperidines; Pirenzepine; Rabbits; Receptors, Muscarinic; Tritium; Urinary Bladder | 1995 |
Evidence for the presence of regional differences in the subtype specificity of muscarinic receptors in rabbit lower urinary tract.
Topics: Animals; Atropine; Carbachol; Diamines; Female; Muscarinic Antagonists; Muscle Contraction; Muscle, Smooth; Parasympatholytics; Pirenzepine; Rabbits; Receptors, Muscarinic; Species Specificity; Urethra; Urinary Bladder | 1997 |
Cholinergic modulation of electrogenic ion transport in different regions of the rat small intestine.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Analysis of Variance; Animals; Atropine; Bethanechol; Carbachol; Chlorides; Diamines; Duodenum; Ileum; Intestinal Mucosa; Ion Transport; Jejunum; Male; Muscarinic Agonists; Muscarinic Antagonists; Piperidines; Pirenzepine; Rats; Rats, Wistar; Receptor, Muscarinic M3; Receptors, Muscarinic; Structure-Activity Relationship; Tetrodotoxin | 1997 |
M3 muscarinic receptor-mediated enhancement of NMDA-evoked adenosine release in rat cortical slices in vitro.
Topics: Adenosine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Atropine; Carbachol; Cerebral Cortex; Diamines; Drug Synergism; In Vitro Techniques; Kinetics; Magnesium; Male; Muscarinic Agonists; Muscarinic Antagonists; N-Methylaspartate; Piperidines; Pirenzepine; Rats; Rats, Wistar; Receptor, Muscarinic M3; Receptors, Muscarinic | 1997 |
Carbachol-induced pressor responses and muscarinic M1 receptors in the central nucleus of amygdala in conscious rats.
Topics: Amygdala; Animals; Blood Pressure; Carbachol; Diamines; Dose-Response Relationship, Drug; Female; Heart Rate; Injections, Intraventricular; Male; Muscarinic Agonists; Muscarinic Antagonists; Parasympatholytics; Pirenzepine; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic | 1997 |
Muscarinic facilitation of GABA release in substantia gelatinosa of the rat spinal dorsal horn.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Animals; Atropine; Carbachol; Diamines; Evoked Potentials; gamma-Aminobutyric Acid; In Vitro Techniques; Interneurons; Muscarinic Agonists; Neostigmine; Neurons; Parasympatholytics; Piperidines; Pirenzepine; Rats; Receptor, Muscarinic M1; Receptors, Muscarinic; Substantia Gelatinosa; Synaptic Transmission; Tetrodotoxin | 1998 |
Characterization of muscarinic receptors mediating the contraction of the urinary detrusor muscle in cynomolgus monkeys and guinea pigs.
Topics: Animals; Carbachol; Diamines; Female; Guinea Pigs; Macaca fascicularis; Male; Muscarinic Agonists; Muscarinic Antagonists; Muscle Contraction; Muscle, Smooth; Piperidines; Pirenzepine; Receptor, Muscarinic M2; Receptors, Muscarinic; Urinary Bladder | 1998 |
Role of nitric oxide production through M2-cholinergic receptors in cultured rat ventricular myocytes.
Topics: Animals; Carbachol; Cells, Cultured; Diamines; Guanylate Cyclase; Heart Ventricles; Muscarinic Antagonists; Myocardial Contraction; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Pirenzepine; Quinuclidinyl Benzilate; Rats; Receptor, Muscarinic M2; Receptors, Muscarinic; Signal Transduction | 1998 |
M2 receptors in genito-urinary smooth muscle pathology.
Topics: Animals; Binding Sites; Carbachol; Diamines; Dose-Response Relationship, Drug; Female; Hypertrophy; Muscarinic Agonists; Muscarinic Antagonists; Muscle Contraction; Muscle Denervation; Muscle, Smooth; Organ Size; Piperidines; Rats; Rats, Sprague-Dawley; Receptor, Muscarinic M2; Receptors, Muscarinic; Spinal Cord Injuries; Urinary Bladder; Urinary Bladder, Neurogenic | 1999 |
Activation of muscarinic M3-like receptors and beta-adrenoceptors, but not M2-like muscarinic receptors or alpha-adrenoceptors, directly modulates corticostriatal neurotransmission in vitro.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; 6-Cyano-7-nitroquinoxaline-2,3-dione; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic beta-Agonists; Adrenergic Fibers; Animals; Carbachol; Cerebral Cortex; Cholinergic Fibers; Corpus Striatum; Diamines; Excitatory Amino Acid Agonists; Excitatory Postsynaptic Potentials; Glutamic Acid; Imidazoles; Isoproterenol; Male; Medetomidine; Mice; Mice, Inbred DBA; Muscarinic Agonists; Muscarinic Antagonists; Phenylephrine; Piperidines; Pirenzepine; Pyrrolidinones; Receptor, Muscarinic M2; Receptor, Muscarinic M3; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Receptors, AMPA; Receptors, Muscarinic; Scopolamine; Synaptic Transmission | 1999 |
Presynaptic muscarinic (M3) receptors reduce excitatory transmission in dopamine neurons of the rat mesencephalon.
Topics: 4-Aminopyridine; Acetylcholine; Animals; Atropine; Carbachol; Diamines; Dicyclomine; Dopamine; Electric Stimulation; Excitatory Postsynaptic Potentials; Mesencephalon; Muscarine; Muscarinic Agonists; Muscarinic Antagonists; Neurons; Parasympatholytics; Physostigmine; Piperidines; Pirenzepine; Presynaptic Terminals; Rats; Rats, Sprague-Dawley; Rats, Wistar; Reaction Time; Receptor, Muscarinic M3; Receptors, Muscarinic; Synaptic Transmission; Tetrodotoxin | 1999 |
Microinjections of carbachol into the phrenic motor nucleus inhibit phrenic nerve activity in the rat.
Topics: Animals; Carbachol; Diamines; Male; Microinjections; Parasympatholytics; Phrenic Nerve; Pirenzepine; Rats; Rats, Wistar; Receptor, Muscarinic M1; Receptor, Muscarinic M2; Receptors, Muscarinic; Spinal Cord | 1999 |
Influence of gender and the oestrous cycle on in vitro contractile responses of the rat urinary bladder to cholinergic stimulation.
Topics: Animals; Carbachol; Cholinergic Agonists; Diamines; Electric Stimulation; Estrus; Female; Male; Muscarinic Antagonists; Parasympatholytics; Piperidines; Pirenzepine; Rats; Rats, Sprague-Dawley; Receptors, Cholinergic; Sex Characteristics; Time Factors; Urinary Bladder; Uterine Contraction | 2000 |
The role of M(2)-muscarinic receptors in mediating contraction of the pig urinary bladder in vitro.
Topics: Animals; Benzofurans; Binding, Competitive; Carbachol; Diamines; Dose-Response Relationship, Drug; Female; In Vitro Techniques; Membranes; Muscarinic Antagonists; Muscle Contraction; Piperidines; Pyrrolidines; Quinuclidinyl Benzilate; Radioligand Assay; Receptor, Muscarinic M2; Receptor, Muscarinic M3; Receptors, Muscarinic; Swine; Tritium; Urinary Bladder | 2000 |
Functional characterization of rat submaxillary gland muscarinic receptors using microphysiometry.
Topics: Alkaloids; Animals; Atropine; Benzhydryl Compounds; Benzodiazepinones; Binding, Competitive; Biosensing Techniques; Carbachol; Cholinergic Agonists; Cresols; Diamines; Dose-Response Relationship, Drug; Furans; Male; Mandelic Acids; Muscarinic Antagonists; Naphthalenes; Phenethylamines; Phenylpropanolamine; Piperidines; Pirenzepine; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic; Submandibular Gland; Tolterodine Tartrate | 2001 |
The antinociceptive and sedative effects of carbachol and oxycodone administered into brainstem pontine reticular formation and spinal subarachnoid space in rats.
Topics: Analgesics, Non-Narcotic; Analgesics, Opioid; Animals; Atropine; Behavior, Animal; Carbachol; Cholinergic Agonists; Conscious Sedation; Diamines; Injections, Spinal; Male; Microinjections; Motor Activity; Muscarinic Antagonists; Pain Threshold; Piperidines; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic; Reticular Formation; Subarachnoid Space | 2001 |
Effect of M2 and M3 muscarinic receptors on airway responsiveness to carbachol in bronchial-hypersensitive (BHS) and bronchial-hyposensitive (BHR) guinea pigs.
Topics: Animals; Bronchial Hyperreactivity; Carbachol; Diamines; Gene Expression; Guinea Pigs; Lung; Male; Muscarinic Antagonists; Muscle Contraction; Muscle, Smooth; Piperidines; Receptor, Muscarinic M2; Receptor, Muscarinic M3; Receptors, Muscarinic; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Trachea | 2001 |
Muscarinic receptors of the M2 subtype in human and bovine trabecular meshwork.
Topics: Animals; Blotting, Western; Carbachol; Cattle; Cell Culture Techniques; Cevanes; Cholinergic Agonists; Diamines; Humans; Isometric Contraction; Molecular Weight; Muscarinic Antagonists; Muscle, Smooth; Parasympatholytics; Receptor, Muscarinic M2; Receptors, Muscarinic; Trabecular Meshwork | 2001 |
Pharmacological characterization of muscarinic receptors in mouse isolated urinary bladder smooth muscle.
Topics: Acetylcholine; Animals; Carbachol; Diamines; Dioxolanes; Dose-Response Relationship, Drug; In Vitro Techniques; Male; Mice; Mice, Inbred C57BL; Muscarinic Agonists; Muscarinic Antagonists; Muscle Contraction; Muscle, Smooth; Oxotremorine; Pilocarpine; Piperidines; Receptors, Muscarinic; Urinary Bladder | 2001 |
Muscarinic activation of inwardly rectifying K(+) conductance reduces EPSPs in rat hippocampal CA1 pyramidal cells.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Carbachol; Cholinergic Agents; Diamines; Excitatory Amino Acid Agonists; Excitatory Postsynaptic Potentials; Gallamine Triethiodide; Glutamic Acid; Hippocampus; Muscarinic Antagonists; Nicotinic Antagonists; Organ Culture Techniques; Parasympatholytics; Patch-Clamp Techniques; Pirenzepine; Potassium Channels, Inwardly Rectifying; Pyramidal Cells; Rats; Rats, Wistar; Receptor, Muscarinic M2; Receptors, Muscarinic; Stimulation, Chemical | 2001 |
Muscarinic receptors control K+ secretion in inner ear strial marginal cells.
Topics: Adrenergic beta-Agonists; Animals; Atropine; Calcium; Carbachol; Cholinergic Agonists; Cloning, Molecular; Cyclic AMP; Diamines; Dose-Response Relationship, Drug; Gerbillinae; Isoproterenol; Muscarinic Antagonists; Parasympatholytics; Piperidines; Pirenzepine; Potassium; Receptors, Muscarinic; Reverse Transcriptase Polymerase Chain Reaction; Stria Vascularis | 2001 |
On the functional role of muscarinic M2 receptors in cholinergic and purinergic responses in the rat urinary bladder.
Topics: 2-Chloroadenosine; Adenosine; Adenosine Triphosphate; Animals; Carbachol; Diamines; Dose-Response Relationship, Drug; In Vitro Techniques; Male; Muscarinic Agonists; Muscarinic Antagonists; Muscle Contraction; Piperidines; Pirenzepine; Purinergic Agonists; Purinergic Antagonists; Rats; Rats, Sprague-Dawley; Receptor, Muscarinic M2; Receptors, Muscarinic; Receptors, Purinergic; Theophylline; Urinary Bladder | 2001 |
Role of muscarinic receptors in the activation of the ventral subiculum and the consequences for dopamine release in the nucleus accumbens.
Topics: Animals; Atropine; Bicuculline; Bridged-Ring Compounds; Carbachol; Cholinergic Agonists; Diamines; Dopamine; Hippocampus; Male; Microdialysis; Muscarinic Agonists; Muscarinic Antagonists; Nicotine; Nucleus Accumbens; Oxotremorine; Pilocarpine; Pyridines; Rats; Receptors, Muscarinic; Spiro Compounds; Thiadiazoles; Tropanes | 2003 |
Heterogeneity of presynaptic muscarinic receptors mediating inhibition of sympathetic transmitter release: a study with M2- and M4-receptor-deficient mice.
Topics: Acetylcholine; Animals; Carbachol; Cholinergic Agonists; Diamines; Genetic Heterogeneity; Heart Atria; Male; Mice; Mice, Knockout; Muscarinic Antagonists; Norepinephrine; Pirenzepine; Receptor, Muscarinic M2; Receptor, Muscarinic M4; Receptors, Muscarinic; Receptors, Presynaptic; Urinary Bladder; Vas Deferens | 2003 |
Cholinergic regulation of the evoked quantal release at frog neuromuscular junction.
Topics: Acetylcholine; Action Potentials; Animals; Arecoline; Carbachol; Cholinergic Agonists; Diamines; Motor Neurons; Muscarinic Agonists; Muscarinic Antagonists; Neural Conduction; Neuromuscular Junction; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Oxotremorine; Parasympatholytics; Pirenzepine; Rana ridibunda; Receptors, Muscarinic; Synaptic Transmission; Tubocurarine | 2004 |
Distinct properties of carbachol- and DHPG-induced network oscillations in hippocampal slices.
Topics: Action Potentials; Amino Acids; Animals; Animals, Newborn; Benzodiazepines; Bicuculline; Carbachol; Cholinergic Agonists; Diamines; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Antagonists; GABA Agonists; GABA Antagonists; Hippocampus; In Vitro Techniques; Male; Methoxyhydroxyphenylglycol; Muscarinic Antagonists; Pirenzepine; Pyridines; Rats; Receptors, Metabotropic Glutamate; Spectrum Analysis; Substance P; Xanthenes; Zolpidem | 2004 |
Carbachol augments Na/Ca exchange current via M2 muscarinic receptors in guinea pig ventricular myocytes.
Topics: Animals; Calcium Channels, L-Type; Carbachol; Cardiotonic Agents; Diamines; Female; Guinea Pigs; Heart Ventricles; Male; Myocytes, Cardiac; Patch-Clamp Techniques; Receptor, Muscarinic M2; Sodium-Calcium Exchanger | 2004 |
M(2) and M(3) muscarinic receptor-mediated contractions in longitudinal smooth muscle of the ileum studied with receptor knockout mice.
Topics: Animals; Calcium Channel Blockers; Carbachol; Cholinergic Agonists; Diamines; Female; Ileum; In Vitro Techniques; Male; Mice; Mice, Knockout; Muscarinic Antagonists; Muscle Contraction; Muscle, Smooth; Nicardipine; Pertussis Toxin; Piperidines; Receptor, Muscarinic M2; Receptor, Muscarinic M3 | 2005 |
Expression and localization of muscarinic acetylcholine receptor subtypes in rat efferent ductules and epididymis.
Topics: Animals; Atropine; Carbachol; Cell Membrane; Diamines; Ejaculatory Ducts; Epididymis; Immunohistochemistry; In Vitro Techniques; Male; Muscarinic Antagonists; Pirenzepine; Rats; Rats, Wistar; Receptors, Muscarinic | 2006 |
Methoctramine and gallamine inhibit PI hydrolysis in guinea-pig gallbladder.
Topics: Animals; Carbachol; Depression, Chemical; Diamines; Female; Gallamine Triethiodide; Gallbladder; Guinea Pigs; Hydrolysis; In Vitro Techniques; Male; Muscarinic Agonists; Muscarinic Antagonists; Phosphatidylinositols; Receptor, Muscarinic M2; Receptor, Muscarinic M4 | 2005 |
Characterization of muscarinic receptor-mediated cationic currents in longitudinal smooth muscle cells of mouse small intestine.
Topics: Animals; Carbachol; Cations; Cholinergic Agonists; Diamines; Dose-Response Relationship, Drug; Enzyme Inhibitors; Estrenes; Guinea Pigs; In Vitro Techniques; Intestine, Small; Ion Channel Gating; Ion Channels; Male; Membrane Potentials; Mice; Muscarinic Antagonists; Myocytes, Smooth Muscle; Pertussis Toxin; Piperidines; Pyrrolidinones; Receptor, Muscarinic M2; Receptor, Muscarinic M3; Type C Phospholipases | 2006 |
Muscarinic regulation of neonatal rat bladder spontaneous contractions.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Animals, Newborn; Calcium Channel Agonists; Carbachol; Cholinergic Agonists; Cholinesterase Inhibitors; Diamines; Electric Stimulation; Muscle Contraction; Muscle Hypertonia; Muscle, Smooth; Parasympatholytics; Peptides; Physostigmine; Piperidines; Pirenzepine; Rats; Rats, Sprague-Dawley; Receptor, Muscarinic M2; Receptor, Muscarinic M3; Urinary Bladder | 2006 |
M2 mediated contractions of human bladder from organ donors is associated with an increase in urothelial muscarinic receptors.
Topics: Adolescent; Adult; Aged; Animals; Benzofurans; Carbachol; Child; Child, Preschool; Cholinergic Agonists; Diamines; Female; Humans; In Vitro Techniques; Male; Middle Aged; Muscarinic Antagonists; Muscle Contraction; Muscle, Smooth; Parasympatholytics; Pyrrolidines; Receptor, Muscarinic M2; Sus scrofa; Tissue Donors; Urinary Bladder; Urothelium | 2007 |
Human idiopathic and neurogenic overactive bladders and the role of M2 muscarinic receptors in contraction.
Topics: Adult; Aged; Benzofurans; Carbachol; Diamines; Dose-Response Relationship, Drug; Female; Humans; In Vitro Techniques; Male; Middle Aged; Muscle Contraction; Muscle, Smooth; Piperidines; Pirenzepine; Pyrrolidines; Receptors, Muscarinic; Urinary Bladder; Urinary Bladder, Neurogenic; Urinary Bladder, Overactive | 2007 |
Changes in muscarinic receptors in the toad urothelial cell line TBM-54 following acrolein treatment.
Topics: Acrolein; Animals; Blotting, Western; Bufo marinus; Carbachol; Cell Line; Diamines; Dose-Response Relationship, Drug; Extracellular Fluid; Hydrogen-Ion Concentration; Muscarinic Agonists; Muscarinic Antagonists; Piperidines; Pirenzepine; Receptors, Muscarinic; Urinary Bladder; Urothelium | 2008 |
Refractoriness of the sheep superior vena cava myocardial sleeve.
Topics: Acetylcholine; Animals; Carbachol; Cholinergic Agonists; Diamines; Electrophysiologic Techniques, Cardiac; In Vitro Techniques; Microelectrodes; Muscarinic Antagonists; Myocardium; Myocytes, Cardiac; Piperidines; Refractometry; Sheep; Tropicamide; Vasodilator Agents; Vena Cava, Superior | 2008 |
Muscarinic cholinergic modulation of synaptic transmission and plasticity in rat hippocampus following chronic lead exposure.
Topics: Animals; Carbachol; Diamines; Environmental Pollutants; Excitatory Postsynaptic Potentials; Female; Hippocampus; In Vitro Techniques; Lead; Learning; Long-Term Potentiation; Male; Memory; Muscarinic Agonists; Muscarinic Antagonists; Neuronal Plasticity; Pirenzepine; Rats; Rats, Wistar; Receptors, Muscarinic; Synaptic Transmission | 2009 |
Carbachol regulates pacemaker activities in cultured interstitial cells of Cajal from the mouse small intestine.
Topics: Animals; Anti-Inflammatory Agents; Biological Clocks; Calcium; Calcium-Transporting ATPases; Carbachol; Cation Transport Proteins; Cells, Cultured; Diamines; Flufenamic Acid; Guanosine Diphosphate; Intestine, Small; Membrane Potentials; Mice; Mice, Inbred BALB C; Neuromuscular Depolarizing Agents; Patch-Clamp Techniques; Piperidines; Plant Roots; Receptor, Muscarinic M2; Receptor, Muscarinic M3; Thapsia; Thapsigargin; Thionucleotides | 2009 |
Comparison of human and porcine gastric clasp and sling fiber contraction by M2 and M3 muscarinic receptors.
Topics: Animals; Benzofurans; Carbachol; Diamines; Dose-Response Relationship, Drug; Esophagogastric Junction; Humans; Isometric Contraction; Muscarinic Antagonists; Muscle Contraction; Muscle, Smooth; Pyrrolidines; Receptor, Muscarinic M2; Receptor, Muscarinic M3; Sus scrofa | 2010 |
Bronchodilator activity of (3R)-3-[[[(3-fluorophenyl)[(3,4,5-trifluorophenyl)methyl]amino] carbonyl]oxy]-1-[2-oxo-2-(2-thienyl)ethyl]-1-azoniabicyclo[2.2.2]octane bromide (CHF5407), a potent, long-acting, and selective muscarinic M3 receptor antagonist.
Topics: Acetylcholine; Aged; Anesthesia; Animals; Blood Pressure; Bronchi; Bronchial Spasm; Bronchoconstriction; Bronchoconstrictor Agents; Bronchodilator Agents; Carbachol; Carbamates; CHO Cells; Cricetinae; Cricetulus; Diamines; Guinea Pigs; Heart Atria; Heart Rate; Humans; Kinetics; Male; Middle Aged; Molecular Structure; Muscarinic Antagonists; Myocardial Contraction; Quinuclidines; Receptor, Muscarinic M1; Receptor, Muscarinic M2; Receptor, Muscarinic M3; Scopolamine Derivatives; Tiotropium Bromide; Trachea; Transfection; Ventricular Function, Left | 2010 |
Colonic inflammation increases the contribution of muscarinic M2 receptors to carbachol-induced contraction of the rat colon.
Topics: Animals; Carbachol; Colitis; Colon; Diamines; Disease Models, Animal; Inflammation; Isometric Contraction; Male; Muscarinic Agonists; Muscarinic Antagonists; Pirenzepine; Rats; Rats, Sprague-Dawley; Receptor, Muscarinic M2 | 2011 |
Urothelial/lamina propria spontaneous activity and the role of M3 muscarinic receptors in mediating rate responses to stretch and carbachol.
Topics: Animals; Atropine; Benzhydryl Compounds; Benzofurans; Carbachol; Cresols; Diamines; Mandelic Acids; Mucous Membrane; Muscarinic Antagonists; Muscle Contraction; Phenylpropanolamine; Piperidines; Pirenzepine; Pyrrolidines; Quinuclidines; Receptor, Muscarinic M3; Solifenacin Succinate; Stress, Mechanical; Swine; Tetrahydroisoquinolines; Tolterodine Tartrate; Urinary Bladder; Urothelium | 2011 |
Muscarinic depolarization of layer II neurons of the parasubiculum.
Topics: Animals; Anthracenes; Carbachol; Cholinergic Agonists; Diamines; KCNQ2 Potassium Channel; KCNQ3 Potassium Channel; Male; Membrane Potentials; Muscarinic Antagonists; Neurons; Parasympatholytics; Pirenzepine; Pyramidal Cells; Rats; Rats, Long-Evans; Receptor, Muscarinic M1 | 2013 |
Activation of muscarinic M3 receptors inhibits large-conductance voltage- and Ca2+-activated K+ channels in rat urinary bladder smooth muscle cells.
Topics: Amphotericin B; Animals; Carbachol; Cholinergic Agonists; Diamines; Evoked Potentials; Gene Expression Regulation; Large-Conductance Calcium-Activated Potassium Channels; Male; Membrane Potentials; Muscarinic Antagonists; Myocytes, Smooth Muscle; Patch-Clamp Techniques; Piperidines; Rats; Rats, Sprague-Dawley; Receptor, Muscarinic M3; Urinary Bladder | 2013 |
The inhibitory effects of antimuscarinic autoantibodies in the sera of primary Sjogren syndrome patients on the gastrointestinal motility.
Topics: Animals; Autoantibodies; Carbachol; Cholinergic Agonists; Colon; Diamines; Dose-Response Relationship, Drug; Gastrointestinal Motility; Humans; In Vitro Techniques; Male; Mice; Mice, Inbred BALB C; Muscarinic Antagonists; Muscle Contraction; Muscle, Smooth; Piperidines; Receptor, Muscarinic M2; Receptor, Muscarinic M3; Sjogren's Syndrome; Stomach | 2013 |
Expression and function of muscarinic subtype receptors in bladder interstitial cells of cajal in rats.
Topics: Action Potentials; Animals; Atropine; Calcium Channels; Carbachol; Cholinergic Agonists; Diamines; Interstitial Cells of Cajal; Male; Muscarinic Antagonists; Patch-Clamp Techniques; Piperidines; Rats; Rats, Sprague-Dawley; Receptor, Muscarinic M2; Receptor, Muscarinic M3; Urinary Bladder | 2014 |