Compounds > methiothepin

methiothepin and sb 269970

methiothepin has been researched along with sb 269970 in 9 studies

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (44.44)29.6817
2010's4 (44.44)24.3611
2020's1 (11.11)2.80

Authors

AuthorsStudies
Glennon, RA1
Bojarski, AJ; Grychowska, K; Kurczab, R; Pawłowski, M; Satała, G; Zajdel, P1
Bienkowski, P; Bucki, A; Jaśkowska, J; Kazek, G; Kowalski, P; Kołaczkowski, M; Marcinkowska, M; Mierzejewski, P; Mitka, K; Pawłowski, M; Siwek, A; Wasik, A; Wesołowska, A1
Bucki, A; Chrzanowska, A; Czopek, A; Drop, M; Głuch-Lutwin, M; Kołaczkowski, M; Partyka, A; Pawłowski, M; Pękala, E; Siwek, A; Struga, M; Wesołowska, A; Zagórska, A1
Lepailleur, A; Rochais, C; Thirumaran, SL1
Bucki, A; Głuch-Lutwin, M; Jakubczyk, M; Jamrozik, M; Jastrzębska-Więsek, M; Kołaczkowski, M; Marcinkowska, M; Mierzejewski, P; Partyka, A; Pawłowski, M; Pytka, K; Siwek, A; Śniecikowska, J; Wesołowska, A; Zagórska, A1
Honda, M; Ono, H1
Feuerbach, D; Loetscher, E; Mahé, C; Müller, W; Schoeffter, P; Seiler, MP1
Andressen, KW; Krobert, KA; Levy, FO1

Reviews

2 review(s) available for methiothepin and sb 269970

ArticleYear
Higher-end serotonin receptors: 5-HT(5), 5-HT(6), and 5-HT(7).
    Journal of medicinal chemistry, 2003, Jul-03, Volume: 46, Issue:14

    Topics: Animals; Humans; Ligands; Receptors, Serotonin; Serotonin Agents; Serotonin Antagonists; Serotonin Receptor Agonists

2003
Structure-activity relationships of serotonin 5-HT
    European journal of medicinal chemistry, 2019, Dec-01, Volume: 183

    Topics: Animals; Humans; Ligands; Receptors, Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Structure-Activity Relationship

2019

Other Studies

7 other study(ies) available for methiothepin and sb 269970

ArticleYear
The multiobjective based design, synthesis and evaluation of the arylsulfonamide/amide derivatives of aryloxyethyl- and arylthioethyl- piperidines and pyrrolidines as a novel class of potent 5-HT₇ receptor antagonists.
    European journal of medicinal chemistry, 2012, Volume: 56

    Topics: Amides; Cells, Cultured; Combinatorial Chemistry Techniques; Dose-Response Relationship, Drug; Drug Design; HEK293 Cells; Humans; Ligands; Models, Molecular; Molecular Structure; Piperidines; Pyrrolidines; Receptors, Serotonin; Serotonin Antagonists; Software; Structure-Activity Relationship

2012
Novel arylsulfonamide derivatives with 5-HT₆/5-HT₇ receptor antagonism targeting behavioral and psychological symptoms of dementia.
    Journal of medicinal chemistry, 2014, Jun-12, Volume: 57, Issue:11

    Topics: Animals; Antidepressive Agents; Antipsychotic Agents; Avoidance Learning; Benzoxazoles; Catalepsy; CHO Cells; Cricetulus; Dementia; Dopamine D2 Receptor Antagonists; HEK293 Cells; Humans; Male; Models, Molecular; Motor Activity; Radioligand Assay; Rats, Wistar; Receptors, Serotonin; Serotonin Antagonists; Structure-Activity Relationship; Sulfonamides

2014
Novel multitarget 5-arylidenehydantoins with arylpiperazinealkyl fragment: Pharmacological evaluation and investigation of cytotoxicity and metabolic stability.
    Bioorganic & medicinal chemistry, 2019, 09-15, Volume: 27, Issue:18

    Topics: Animals; Antidepressive Agents; Depression; Disease Models, Animal; Humans; Receptors, Serotonin; Structure-Activity Relationship

2019
Multifunctional 6-fluoro-3-[3-(pyrrolidin-1-yl)propyl]-1,2-benzoxazoles targeting behavioral and psychological symptoms of dementia (BPSD).
    European journal of medicinal chemistry, 2020, Apr-01, Volume: 191

    Topics: Animals; Antipsychotic Agents; Behavior, Animal; Benzoxazoles; Dementia; Dizocilpine Maleate; Dose-Response Relationship, Drug; Ether-A-Go-Go Potassium Channels; Humans; Male; Mice; Models, Molecular; Molecular Structure; Structure-Activity Relationship

2020
No involvement of 5-HT(7) or 5-HT(1D) receptors in the (R)-8-OH-DPAT-induced depression of the monosynaptic reflex in spinalized rats.
    European journal of pharmacology, 2001, Sep-14, Volume: 427, Issue:2

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Clozapine; Decerebrate State; Dose-Response Relationship, Drug; Ergolines; Indoles; Male; Methiothepin; Oxadiazoles; Phenols; Piperazines; Pyridines; Rats; Receptor, Serotonin, 5-HT1D; Receptors, Serotonin; Reflex, Monosynaptic; Serotonin Antagonists; Serotonin Receptor Agonists; Sulfonamides; Time Factors

2001
Differential inverse agonist efficacies of SB-258719, SB-258741 and SB-269970 at human recombinant serotonin 5-HT7 receptors.
    European journal of pharmacology, 2004, Jul-14, Volume: 495, Issue:2-3

    Topics: Animals; Binding, Competitive; CHO Cells; Clozapine; Cricetinae; Cricetulus; Cyclic AMP; Dose-Response Relationship, Drug; Ergolines; Humans; Loxapine; Methiothepin; Phenols; Pimozide; Pindolol; Piperidines; Plasmids; Pyrrolidines; Radioligand Assay; Receptors, Serotonin; Ritanserin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Sulfonamides; Tosyl Compounds; Transfection

2004
Heterologous desensitization is evoked by both agonist and antagonist stimulation of the human 5-HT(7) serotonin receptor.
    European journal of pharmacology, 2006, Feb-17, Volume: 532, Issue:1-2

    Topics: Adenylyl Cyclases; Alternative Splicing; Binding, Competitive; Cell Line; Cell Membrane; Clozapine; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Ergolines; Gene Expression; Humans; Isoproterenol; Isoquinolines; Methiothepin; Multivariate Analysis; Phenols; Protein Isoforms; Protein Kinase Inhibitors; Radioligand Assay; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Sulfonamides; Time Factors; Tritium

2006