methiothepin and ritanserin

methiothepin has been researched along with ritanserin in 30 studies

Research

Studies (30)

TimeframeStudies, this research(%)All Research%
pre-19902 (6.67)18.7374
1990's18 (60.00)18.2507
2000's10 (33.33)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hamblin, MW; Monsma, FJ; Shen, Y; Sibley, DR; Ward, RP1
Adham, N; Bard, JA; Branchek, TA; Vaysse, P; Weinshank, RL; Zgombick, J1
Hamblin, MW; Jose, PA; Metcalf, MA; Monsma, FJ; Shen, Y; Sibley, DR1
Druck, T; Hamblin, MW; Huebner, K; Khan, N; Kohen, R; Lachowicz, JE; Meltzer, HY; Metcalf, MA; Roth, BL; Sibley, DR1
Gommeren, W; Haegeman, G; Heylen, L; Lesage, AS; Leysen, JE; Luyten, WH; Schotte, A; Van de Weyer, I; Van Gompel, P; Vanhoenacker, P; Wouters, R1
Boess, FG; Meyer, V; Monsma, FJ; Sleight, AJ; Zwingelstein, C1
Beleta, J; Doménech, T; Palacios, JM1
Baez, M; Kursar, JD; Lucaites, VL; Nelson, DL; Sasso, DA; Wainscott, DB1
Bentley, J; Boess, FG; Bös, M; Bourson, A; Riemer, C; Sleight, AJ1
Boess, FG; Monsma, FJ; Sleight, AJ1
Grabtree, GW; Grailhe, R; Hen, R1
Bach, T; Krobert, KA; Kvingedal, AM; Levy, FO; Syversveen, T1
Glennon, RA1
Benwell, K; Bickerdike, M; Kennett, G; Knight, AR; Misra, A; Quirk, K; Revell, D1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Holmgren, B; Leon, BA; Ugarte, A; Urbá-Holmgren, R1
Carlsson, S; Hoffmann, P; Skarphedinsson, JO; Thorén, P1
Gibb, JW; Hanson, GR; Johnson, M1
Ramage, AG1
Björklund, M; Jäkälä, P; Kaukua, J; Koivisto, E; Riekkinen, P; Sirviö, J1
Hong, E; López-Muñoz, FJ; Terrón, JA; Villalón, CM1
Branchek, TA; Kucharewicz, SA; Schechter, LE; Weinshank, RL; Zgombick, JM1
Böing, C; Bühlen, M; Fink, K; Göthert, M1
Dudley, MW; Kehne, JH; Ketteler, HJ; McCloskey, TC; Schmidt, CJ; Sullivan, CK1
Kaisar, M; Naylor, RJ; Tuladhar, BR1
Chi, J; Stephens, RL; Varanasi, S1
Feuerbach, D; Loetscher, E; Mahé, C; Müller, W; Schoeffter, P; Seiler, MP1
Calama, E; Martín, ML; Morán, A; Ortíz de Urbina, AV; San Román, L1
Centurión, D; Gupta, S; Mehrotra, S; Saxena, PR; VandenBrink, AM; Villalón, CM1
Bray, JK; Goddard, WA1

Reviews

1 review(s) available for methiothepin and ritanserin

ArticleYear
Higher-end serotonin receptors: 5-HT(5), 5-HT(6), and 5-HT(7).
    Journal of medicinal chemistry, 2003, Jul-03, Volume: 46, Issue:14

    Topics: Animals; Humans; Ligands; Receptors, Serotonin; Serotonin Agents; Serotonin Antagonists; Serotonin Receptor Agonists

2003

Other Studies

29 other study(ies) available for methiothepin and ritanserin

ArticleYear
Cloning and expression of a novel serotonin receptor with high affinity for tricyclic psychotropic drugs.
    Molecular pharmacology, 1993, Volume: 43, Issue:3

    Topics: Amino Acid Sequence; Animals; Base Sequence; Binding, Competitive; Blotting, Northern; Brain Chemistry; Cell Line; Cloning, Molecular; DNA; GTP-Binding Proteins; Lysergic Acid Diethylamide; Molecular Sequence Data; Polymerase Chain Reaction; Psychotropic Drugs; Rats; Receptors, Serotonin; RNA; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Transfection

1993
Cloning of a novel human serotonin receptor (5-HT7) positively linked to adenylate cyclase.
    The Journal of biological chemistry, 1993, Nov-05, Volume: 268, Issue:31

    Topics: Adenylyl Cyclases; Base Sequence; Cloning, Molecular; DNA Primers; Humans; Molecular Sequence Data; Receptors, Serotonin; Sequence Alignment; Sequence Homology, Amino Acid; Serotonin Antagonists; Serotonin Receptor Agonists; Signal Transduction

1993
Molecular cloning and expression of a 5-hydroxytryptamine7 serotonin receptor subtype.
    The Journal of biological chemistry, 1993, Aug-25, Volume: 268, Issue:24

    Topics: Amino Acid Sequence; Animals; Base Sequence; Binding, Competitive; Cell Line; Cell Membrane; Cloning, Molecular; Cyclic AMP; Gene Expression; Kidney Tubules, Proximal; Lysergic Acid Diethylamide; Molecular Sequence Data; Oligodeoxyribonucleotides; Polymerase Chain Reaction; Radioligand Assay; Rats; Receptors, Serotonin; Recombinant Proteins; Serotonin; Transfection

1993
Cloning, characterization, and chromosomal localization of a human 5-HT6 serotonin receptor.
    Journal of neurochemistry, 1996, Volume: 66, Issue:1

    Topics: Adenylyl Cyclases; Amino Acid Sequence; Animals; Antipsychotic Agents; Base Sequence; Brain Chemistry; Cell Line, Transformed; Chlorocebus aethiops; Chromosome Mapping; Chromosomes, Human, Pair 1; Cloning, Molecular; Clozapine; DNA, Complementary; Genes; Humans; Kinetics; Molecular Sequence Data; Open Reading Frames; Protein Conformation; Rats; Receptors, Serotonin; Recombinant Proteins; Sequence Alignment; Sequence Homology, Nucleic Acid; Serotonin Agents; Signal Transduction; Species Specificity

1996
Alniditan, a new 5-hydroxytryptamine1D agonist and migraine-abortive agent: ligand-binding properties of human 5-hydroxytryptamine1D alpha, human 5-hydroxytryptamine1D beta, and calf 5-hydroxytryptamine1D receptors investigated with [3H]5-hydroxytryptamin
    Molecular pharmacology, 1996, Volume: 50, Issue:6

    Topics: Animals; Benzopyrans; Cattle; Cloning, Molecular; Glioma; HeLa Cells; Humans; Mice; Migraine Disorders; Propylamines; Protein Binding; Pyrimidines; Radioligand Assay; Receptors, Serotonin; Serotonin Receptor Agonists; Signal Transduction; Tritium; Tumor Cells, Cultured; Vasoconstrictor Agents

1996
Interaction of tryptamine and ergoline compounds with threonine 196 in the ligand binding site of the 5-hydroxytryptamine6 receptor.
    Molecular pharmacology, 1997, Volume: 52, Issue:3

    Topics: Amino Acid Sequence; Animals; Binding Sites; Cells, Cultured; Cloning, Molecular; Cricetinae; Dogs; Drug Interactions; Ergolines; Guinea Pigs; Humans; Kidney; Ligands; Lysergic Acid Diethylamide; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Rats; Receptors, Serotonin; Sequence Homology, Amino Acid; Serotonin; Threonine; Tryptamines

1997
Characterization of human serotonin 1D and 1B receptors using [3H]-GR-125743, a novel radiolabelled serotonin 5HT1D/1B receptor antagonist.
    Naunyn-Schmiedeberg's archives of pharmacology, 1997, Volume: 356, Issue:3

    Topics: Benzamides; Binding, Competitive; Gene Expression; HeLa Cells; Humans; Kinetics; Ligands; Pyridines; Receptor, Serotonin, 5-HT1B; Receptor, Serotonin, 5-HT1D; Receptors, Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Substantia Nigra; Tritium

1997
[3H]Rauwolscine: an antagonist radioligand for the cloned human 5-hydroxytryptamine2b (5-HT2B) receptor.
    Naunyn-Schmiedeberg's archives of pharmacology, 1998, Volume: 357, Issue:1

    Topics: Adrenergic alpha-Antagonists; Benzofurans; Binding, Competitive; Cell Line; Cloning, Molecular; Humans; Imidazoles; Radioligand Assay; Receptor, Serotonin, 5-HT2B; Receptors, Serotonin; Serotonin Antagonists; Transfection; Tritium; Yohimbine

1998
The 5-hydroxytryptamine6 receptor-selective radioligand [3H]Ro 63-0563 labels 5-hydroxytryptamine receptor binding sites in rat and porcine striatum.
    Molecular pharmacology, 1998, Volume: 54, Issue:3

    Topics: Aminopyridines; Animals; Binding Sites; Corpus Striatum; HeLa Cells; Humans; Radioligand Assay; Rats; Receptors, Serotonin; Serotonin Antagonists; Species Specificity; Swine; Tritium

1998
Identification of residues in transmembrane regions III and VI that contribute to the ligand binding site of the serotonin 5-HT6 receptor.
    Journal of neurochemistry, 1998, Volume: 71, Issue:5

    Topics: Adenylyl Cyclases; Amino Acid Substitution; Binding Sites; Binding, Competitive; Cell Line; Cyclic AMP; Humans; Ligands; Lysergic Acid Diethylamide; Mutagenesis, Site-Directed; Mutation; Receptors, Serotonin; Serotonin; Serotonin Receptor Agonists

1998
Human 5-HT(5) receptors: the 5-HT(5A) receptor is functional but the 5-HT(5B) receptor was lost during mammalian evolution.
    European journal of pharmacology, 2001, Apr-27, Volume: 418, Issue:3

    Topics: 3T3 Cells; Amino Acid Sequence; Animals; Base Sequence; Binding, Competitive; Cell Line; COS Cells; DNA; Evolution, Molecular; Gene Expression; Genes; Humans; Membranes; Mice; Molecular Sequence Data; Phylogeny; Radioligand Assay; Receptors, Serotonin; Sequence Alignment; Sequence Analysis, DNA; Sequence Homology, Amino Acid

2001
The cloned human 5-HT7 receptor splice variants: a comparative characterization of their pharmacology, function and distribution.
    Naunyn-Schmiedeberg's archives of pharmacology, 2001, Volume: 363, Issue:6

    Topics: Adenylyl Cyclases; Alternative Splicing; Binding, Competitive; Brain; Cell Line; Cloning, Organism; Genetic Variation; Humans; Radioligand Assay; Receptors, Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Tissue Distribution

2001
Pharmacological characterisation of the agonist radioligand binding site of 5-HT(2A), 5-HT(2B) and 5-HT(2C) receptors.
    Naunyn-Schmiedeberg's archives of pharmacology, 2004, Volume: 370, Issue:2

    Topics: Binding Sites; Binding, Competitive; Cell Line; Humans; Radioligand Assay; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2B; Receptor, Serotonin, 5-HT2C; Recombinant Proteins; Serotonin 5-HT2 Receptor Agonists; Serotonin 5-HT2 Receptor Antagonists; Serotonin Antagonists; Serotonin Receptor Agonists

2004
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
Age-dependent changes in serotonergic modulation of yawning in the rat.
    Pharmacology, biochemistry, and behavior, 1992, Volume: 43, Issue:2

    Topics: Aging; Animals; Citalopram; Male; Methiothepin; Physostigmine; Rats; Rats, Sprague-Dawley; Ritanserin; Serotonin; Serotonin Antagonists; Yawning

1992
Role of different serotonergic receptors in the long-lasting blood pressure depression following muscle stimulation in the spontaneously hypertensive rat.
    Acta physiologica Scandinavica, 1990, Volume: 139, Issue:2

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Blood Pressure; Electric Stimulation; Heart Rate; Indoles; Male; Methiothepin; Muscles; Piperidines; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Receptors, Serotonin; Ritanserin; Serotonin Antagonists; Tetrahydronaphthalenes; Time Factors; Tropisetron

1990
Effects of dopaminergic and serotonergic receptor blockade on neurochemical changes induced by acute administration of methamphetamine and 3,4-methylenedioxymethamphetamine.
    Neuropharmacology, 1988, Volume: 27, Issue:11

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; Animals; Haloperidol; Male; Methamphetamine; Methiothepin; Piperidines; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Serotonin; Ritanserin; Serotonin Antagonists

1988
Examination of the effects of some 5-HT2 receptor antagonists on central sympathetic outflow and blood pressure in anaesthetised cats.
    Naunyn-Schmiedeberg's archives of pharmacology, 1988, Volume: 338, Issue:6

    Topics: Anesthesia; Animals; Blood Pressure; Cats; Cinanserin; Cyproheptadine; Male; Metergoline; Methiothepin; Piperidines; Quinolines; Ritanserin; Serotonin Antagonists; Sympathetic Nervous System

1988
Modulation of rat neocortical high-voltage spindle activity by 5-HT1/5-HT2 receptor subtype specific drugs.
    European journal of pharmacology, 1995, Aug-25, Volume: 282, Issue:1-3

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Analysis of Variance; Animals; Cerebral Cortex; Electroencephalography; Infusions, Parenteral; Ketanserin; Male; Methiothepin; Methysergide; Neural Pathways; Rats; Rats, Wistar; Receptors, Serotonin; Ritanserin; Thalamus

1995
Inhibition of serotonin-induced increase in canine external carotid blood flow by drugs that decrease the sympathetic outflow.
    Journal of autonomic pharmacology, 1994, Volume: 14, Issue:3

    Topics: Animals; Blood Pressure; Carotid Arteries; Dioxanes; Dogs; Dose-Response Relationship, Drug; Female; Heart Rate; Infusions, Intra-Arterial; Injections, Intravenous; Ketanserin; Male; Mecamylamine; Methiothepin; Prazosin; Receptors, Serotonin; Regional Blood Flow; Regression Analysis; Ritanserin; Serotonin; Spiro Compounds; Vascular Resistance

1994
Ketanserin and ritanserin discriminate between recombinant human 5-HT1D alpha and 5-HT1D beta receptor subtypes.
    European journal of pharmacology, 1995, Sep-15, Volume: 291, Issue:1

    Topics: Binding, Competitive; Humans; Ketanserin; Methiothepin; Radioligand Assay; Receptors, Serotonin; Recombinant Proteins; Ritanserin; Second Messenger Systems; Serotonin Antagonists

1995
Evidence for presynaptic location of inhibitory 5-HT1D beta-like autoreceptors in the guinea-pig brain cortex.
    Naunyn-Schmiedeberg's archives of pharmacology, 1996, Volume: 353, Issue:3

    Topics: Animals; Autoreceptors; Binding, Competitive; Cerebral Cortex; Guinea Pigs; Humans; Indoles; Ketanserin; Male; Methiothepin; Oxadiazoles; Oxymetazoline; Potassium; Radioligand Assay; Receptors, Serotonin; Ritanserin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Structure-Activity Relationship; Sumatriptan; Synaptosomes; Tritium; Tryptamines

1996
Effects of the selective 5-HT2A receptor antagonist MDL 100,907 on MDMA-induced locomotor stimulation in rats.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 1996, Volume: 15, Issue:2

    Topics: 5,7-Dihydroxytryptamine; Animals; Brain Chemistry; Clozapine; Dopamine Antagonists; Fluorobenzenes; Male; Methiothepin; Motor Activity; N-Methyl-3,4-methylenedioxyamphetamine; Piperidines; Presynaptic Terminals; Rats; Receptors, Neurotransmitter; Ritanserin; Serotonin; Serotonin Agents; Serotonin Antagonists; Stimulation, Chemical

1996
Evidence for a 5-HT3 receptor involvement in the facilitation of peristalsis on mucosal application of 5-HT in the guinea pig isolated ileum.
    British journal of pharmacology, 1997, Volume: 122, Issue:6

    Topics: Animals; Dioxanes; Female; Granisetron; Guinea Pigs; Ileum; In Vitro Techniques; Male; Methiothepin; Mucous Membrane; Ondansetron; Peristalsis; Piperidines; Receptors, Serotonin; Receptors, Serotonin, 5-HT3; Ritanserin; Serotonin; Serotonin Antagonists

1997
Methiothepin attenuates gastric secretion and motility effects of vagal stimulants at the dorsal vagal complex.
    European journal of pharmacology, 2002, Feb-01, Volume: 436, Issue:1-2

    Topics: Animals; Dose-Response Relationship, Drug; Gastric Acid; Gastrointestinal Motility; Glutamic Acid; Kainic Acid; Male; Methiothepin; Methysergide; Pindolol; Raphe Nuclei; Rats; Rats, Sprague-Dawley; Ritanserin; Serotonin Antagonists; Solitary Nucleus; Time Factors; Vagus Nerve

2002
Differential inverse agonist efficacies of SB-258719, SB-258741 and SB-269970 at human recombinant serotonin 5-HT7 receptors.
    European journal of pharmacology, 2004, Jul-14, Volume: 495, Issue:2-3

    Topics: Animals; Binding, Competitive; CHO Cells; Clozapine; Cricetinae; Cricetulus; Cyclic AMP; Dose-Response Relationship, Drug; Ergolines; Humans; Loxapine; Methiothepin; Phenols; Pimozide; Pindolol; Piperidines; Plasmids; Pyrrolidines; Radioligand Assay; Receptors, Serotonin; Ritanserin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Sulfonamides; Tosyl Compounds; Transfection

2004
Effect of 5-hydroxytryptamine on neurogenic vasoconstriction in the isolated, autoperfused hindquarters of the rat.
    Clinical and experimental pharmacology & physiology, 2005, Volume: 32, Issue:10

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Biguanides; Biphenyl Compounds; Dose-Response Relationship, Drug; Electric Stimulation; Hindlimb; In Vitro Techniques; Infusions, Intravenous; Male; Methiothepin; Oxadiazoles; Perfusion; Piperazines; Pressure; Quinoxalines; Rats; Rats, Wistar; Ritanserin; Serotonin; Serotonin 5-HT1 Receptor Agonists; Serotonin 5-HT2 Receptor Agonists; Serotonin 5-HT3 Receptor Agonists; Serotonin Agents; Serotonin Antagonists; Serotonin Receptor Agonists; Tryptamines; Vasoconstriction

2005
A61603-induced contractions of the porcine meningeal artery are mediated by alpha1- and alpha2-adrenoceptors.
    Basic & clinical pharmacology & toxicology, 2007, Volume: 100, Issue:4

    Topics: Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Antagonists; Alkaloids; Animals; Benzophenanthridines; Colforsin; Dose-Response Relationship, Drug; Female; Forecasting; Imidazoles; In Vitro Techniques; Meningeal Arteries; Methiothepin; Norepinephrine; Oxadiazoles; Phenylephrine; Piperazines; Potassium Chloride; Prazosin; Protein Kinase C; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2; Ritanserin; Serotonin 5-HT1 Receptor Antagonists; Serotonin Antagonists; Swine; Tetrahydronaphthalenes; Vasoconstriction; Yohimbine

2007
The structure of human serotonin 2c G-protein-coupled receptor bound to agonists and antagonists.
    Journal of molecular graphics & modelling, 2008, Volume: 27, Issue:1

    Topics: Amino Acid Sequence; Binding Sites; Humans; Kinetics; Metergoline; Methiothepin; Molecular Sequence Data; Mutagenesis; Protein Structure, Secondary; Psilocybin; Receptor, Serotonin, 5-HT2B; Receptor, Serotonin, 5-HT2C; Ritanserin; Serotonin; Serotonin 5-HT2 Receptor Agonists; Serotonin 5-HT2 Receptor Antagonists; Structure-Activity Relationship; Thermodynamics

2008