methiothepin and mianserin

methiothepin has been researched along with mianserin in 25 studies

Research

Studies (25)

TimeframeStudies, this research(%)All Research%
pre-19906 (24.00)18.7374
1990's10 (40.00)18.2507
2000's6 (24.00)29.6817
2010's2 (8.00)24.3611
2020's1 (4.00)2.80

Authors

AuthorsStudies
Hamblin, MW; Monsma, FJ; Shen, Y; Sibley, DR; Ward, RP1
Hamblin, MW; Jose, PA; Metcalf, MA; Monsma, FJ; Shen, Y; Sibley, DR1
Amlaiky, N; Hen, R; Plassat, JL1
Druck, T; Hamblin, MW; Huebner, K; Khan, N; Kohen, R; Lachowicz, JE; Meltzer, HY; Metcalf, MA; Roth, BL; Sibley, DR1
Boess, FG; Meyer, V; Monsma, FJ; Sleight, AJ; Zwingelstein, C1
Chang, DJ; Eglen, RM; Jasper, JR; Kosaka, A; To, ZP1
Baez, M; Kursar, JD; Lucaites, VL; Nelson, DL; Sasso, DA; Wainscott, DB1
Bentley, J; Boess, FG; Bös, M; Bourson, A; Riemer, C; Sleight, AJ1
Andersen, K; Balle, T; Larsen, AK; Liljefors, T; Perregaard, J; Ramirez, MT; Søby, KK1
Glennon, RA1
Benwell, K; Bickerdike, M; Kennett, G; Knight, AR; Misra, A; Quirk, K; Revell, D1
Buck, LB; Petrascheck, M; Ye, X1
Bączek, T; Belka, M; Bojarski, A; Herold, F; Kleps, J; Kozioł, AE; Król, M; Nowak, G; Podsadni, P; Siwek, A; Ślifirski, G; Stachowicz, K; Szewczyk, B; Turło, J1
Bucki, A; Chrzanowska, A; Czopek, A; Drop, M; Głuch-Lutwin, M; Kołaczkowski, M; Partyka, A; Pawłowski, M; Pękala, E; Siwek, A; Struga, M; Wesołowska, A; Zagórska, A1
Bucki, A; Głuch-Lutwin, M; Jakubczyk, M; Jamrozik, M; Jastrzębska-Więsek, M; Kołaczkowski, M; Marcinkowska, M; Mierzejewski, P; Partyka, A; Pawłowski, M; Pytka, K; Siwek, A; Śniecikowska, J; Wesołowska, A; Zagórska, A1
Segal, M1
Barnett, A; Malick, JB1
Schönbaum, E; Van Proosdij, J; Van Riezen, H1
Jenner, P; Marsden, CD; Stewart, BR1
Berge, OG1
Segawa, T; Uehara, M1
Gobbi, M; Mennini, T; Parotti, L1
Nishida, A; Shimizu, M; Yamawaki, S; Zensho, H1
Boyle, JP; Yoshino, TP; Zaide, JV1
Ristow, M; Zarse, K1

Reviews

1 review(s) available for methiothepin and mianserin

ArticleYear
Higher-end serotonin receptors: 5-HT(5), 5-HT(6), and 5-HT(7).
    Journal of medicinal chemistry, 2003, Jul-03, Volume: 46, Issue:14

    Topics: Animals; Humans; Ligands; Receptors, Serotonin; Serotonin Agents; Serotonin Antagonists; Serotonin Receptor Agonists

2003

Other Studies

24 other study(ies) available for methiothepin and mianserin

ArticleYear
Cloning and expression of a novel serotonin receptor with high affinity for tricyclic psychotropic drugs.
    Molecular pharmacology, 1993, Volume: 43, Issue:3

    Topics: Amino Acid Sequence; Animals; Base Sequence; Binding, Competitive; Blotting, Northern; Brain Chemistry; Cell Line; Cloning, Molecular; DNA; GTP-Binding Proteins; Lysergic Acid Diethylamide; Molecular Sequence Data; Polymerase Chain Reaction; Psychotropic Drugs; Rats; Receptors, Serotonin; RNA; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Transfection

1993
Molecular cloning and expression of a 5-hydroxytryptamine7 serotonin receptor subtype.
    The Journal of biological chemistry, 1993, Aug-25, Volume: 268, Issue:24

    Topics: Amino Acid Sequence; Animals; Base Sequence; Binding, Competitive; Cell Line; Cell Membrane; Cloning, Molecular; Cyclic AMP; Gene Expression; Kidney Tubules, Proximal; Lysergic Acid Diethylamide; Molecular Sequence Data; Oligodeoxyribonucleotides; Polymerase Chain Reaction; Radioligand Assay; Rats; Receptors, Serotonin; Recombinant Proteins; Serotonin; Transfection

1993
Molecular cloning of a mammalian serotonin receptor that activates adenylate cyclase.
    Molecular pharmacology, 1993, Volume: 44, Issue:2

    Topics: Adenylyl Cyclases; Amino Acid Sequence; Animals; Base Sequence; Brain; Cloning, Molecular; Cyclic AMP; DNA; Drosophila; Enzyme Activation; Humans; Intestinal Mucosa; Mice; Molecular Sequence Data; Myocardium; Receptors, Serotonin; Sequence Homology, Amino Acid; Serotonin Antagonists; Serotonin Receptor Agonists

1993
Cloning, characterization, and chromosomal localization of a human 5-HT6 serotonin receptor.
    Journal of neurochemistry, 1996, Volume: 66, Issue:1

    Topics: Adenylyl Cyclases; Amino Acid Sequence; Animals; Antipsychotic Agents; Base Sequence; Brain Chemistry; Cell Line, Transformed; Chlorocebus aethiops; Chromosome Mapping; Chromosomes, Human, Pair 1; Cloning, Molecular; Clozapine; DNA, Complementary; Genes; Humans; Kinetics; Molecular Sequence Data; Open Reading Frames; Protein Conformation; Rats; Receptors, Serotonin; Recombinant Proteins; Sequence Alignment; Sequence Homology, Nucleic Acid; Serotonin Agents; Signal Transduction; Species Specificity

1996
Interaction of tryptamine and ergoline compounds with threonine 196 in the ligand binding site of the 5-hydroxytryptamine6 receptor.
    Molecular pharmacology, 1997, Volume: 52, Issue:3

    Topics: Amino Acid Sequence; Animals; Binding Sites; Cells, Cultured; Cloning, Molecular; Cricetinae; Dogs; Drug Interactions; Ergolines; Guinea Pigs; Humans; Kidney; Ligands; Lysergic Acid Diethylamide; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Rats; Receptors, Serotonin; Sequence Homology, Amino Acid; Serotonin; Threonine; Tryptamines

1997
Cloning, expression and pharmacology of a truncated splice variant of the human 5-HT7 receptor (h5-HT7b).
    British journal of pharmacology, 1997, Volume: 122, Issue:1

    Topics: Alternative Splicing; Amino Acid Sequence; Animals; Base Sequence; Cloning, Molecular; Cyclic AMP; DNA, Complementary; Humans; Molecular Sequence Data; Placenta; Radioligand Assay; Rats; Receptors, Serotonin; RNA, Messenger; Sequence Homology, Amino Acid; Sequence Homology, Nucleic Acid

1997
[3H]Rauwolscine: an antagonist radioligand for the cloned human 5-hydroxytryptamine2b (5-HT2B) receptor.
    Naunyn-Schmiedeberg's archives of pharmacology, 1998, Volume: 357, Issue:1

    Topics: Adrenergic alpha-Antagonists; Benzofurans; Binding, Competitive; Cell Line; Cloning, Molecular; Humans; Imidazoles; Radioligand Assay; Receptor, Serotonin, 5-HT2B; Receptors, Serotonin; Serotonin Antagonists; Transfection; Tritium; Yohimbine

1998
The 5-hydroxytryptamine6 receptor-selective radioligand [3H]Ro 63-0563 labels 5-hydroxytryptamine receptor binding sites in rat and porcine striatum.
    Molecular pharmacology, 1998, Volume: 54, Issue:3

    Topics: Aminopyridines; Animals; Binding Sites; Corpus Striatum; HeLa Cells; Humans; Radioligand Assay; Rats; Receptors, Serotonin; Serotonin Antagonists; Species Specificity; Swine; Tritium

1998
Synthesis and structure-affinity relationship investigations of 5-heteroaryl-substituted analogues of the antipsychotic sertindole. A new class of highly selective alpha(1) adrenoceptor antagonists.
    Journal of medicinal chemistry, 2003, Jan-16, Volume: 46, Issue:2

    Topics: Adrenergic alpha-Antagonists; Animals; Antipsychotic Agents; Azoles; Brain; Cell Line; Cricetinae; Humans; Imidazoles; In Vitro Techniques; Indoles; Pyridines; Pyrimidines; Radioligand Assay; Rats; Receptors, Adrenergic, alpha-1; Receptors, Dopamine; Receptors, Serotonin; Structure-Activity Relationship; Triazoles

2003
Pharmacological characterisation of the agonist radioligand binding site of 5-HT(2A), 5-HT(2B) and 5-HT(2C) receptors.
    Naunyn-Schmiedeberg's archives of pharmacology, 2004, Volume: 370, Issue:2

    Topics: Binding Sites; Binding, Competitive; Cell Line; Humans; Radioligand Assay; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2B; Receptor, Serotonin, 5-HT2C; Recombinant Proteins; Serotonin 5-HT2 Receptor Agonists; Serotonin 5-HT2 Receptor Antagonists; Serotonin Antagonists; Serotonin Receptor Agonists

2004
An antidepressant that extends lifespan in adult Caenorhabditis elegans.
    Nature, 2007, Nov-22, Volume: 450, Issue:7169

    Topics: Aging; Animals; Antidepressive Agents; Caenorhabditis elegans; Caloric Restriction; Humans; Longevity; Methiothepin; Mianserin; Octopamine; Receptors, Biogenic Amine; Receptors, Serotonin, 5-HT4; Serotonin; Serotonin 5-HT4 Receptor Antagonists; Serotonin Antagonists; Signal Transduction; Starvation

2007
Synthesis of new 5,6,7,8-tetrahydropyrido[1,2-c]pyrimidine derivatives with rigidized tryptamine moiety as potential SSRI and 5-HT
    European journal of medicinal chemistry, 2019, Oct-15, Volume: 180

    Topics: Animals; Cells, Cultured; Crystallography, X-Ray; Dose-Response Relationship, Drug; HEK293 Cells; Humans; Ligands; Male; Mice; Models, Molecular; Molecular Structure; Pyrimidines; Rats; Receptor, Serotonin, 5-HT1A; RNA-Binding Proteins; Structure-Activity Relationship; Tryptamines

2019
Novel multitarget 5-arylidenehydantoins with arylpiperazinealkyl fragment: Pharmacological evaluation and investigation of cytotoxicity and metabolic stability.
    Bioorganic & medicinal chemistry, 2019, 09-15, Volume: 27, Issue:18

    Topics: Animals; Antidepressive Agents; Depression; Disease Models, Animal; Humans; Receptors, Serotonin; Structure-Activity Relationship

2019
Multifunctional 6-fluoro-3-[3-(pyrrolidin-1-yl)propyl]-1,2-benzoxazoles targeting behavioral and psychological symptoms of dementia (BPSD).
    European journal of medicinal chemistry, 2020, Apr-01, Volume: 191

    Topics: Animals; Antipsychotic Agents; Behavior, Animal; Benzoxazoles; Dementia; Dizocilpine Maleate; Dose-Response Relationship, Drug; Ether-A-Go-Go Potassium Channels; Humans; Male; Mice; Models, Molecular; Molecular Structure; Structure-Activity Relationship

2020
5-HT antagonists in rat hippocampus.
    Brain research, 1976, Feb-13, Volume: 103, Issue:1

    Topics: Acetylcholine; Animals; Bicuculline; Cinanserin; Cyproheptadine; Evoked Potentials; gamma-Aminobutyric Acid; Hippocampus; Lysergic Acid Diethylamide; Male; Methiothepin; Methysergide; Mianserin; Norepinephrine; Picrotoxin; Rats; Serotonin; Serotonin Antagonists; Stimulation, Chemical

1976
The role of serotonergic pathways in isolation-induced aggression in mice.
    Pharmacology, biochemistry, and behavior, 1976, Volume: 5, Issue:1

    Topics: 5-Hydroxytryptophan; Aggression; Amidines; Animals; Cinanserin; Cyproheptadine; Depression, Chemical; Drug Interactions; Fenclonine; Humans; Male; Methiothepin; Methysergide; Mianserin; Mice; Motor Activity; Neural Pathways; Phenyl Ethers; Physostigmine; Pizotyline; Receptors, Serotonin; Scopolamine; Serotonin; Social Isolation

1976
Effects of various drugs supposed to interact with serotonin on PGO frequency changes induced by reserpine and 5-hydroxytryptophan.
    Monographs in neural sciences, 1976, Volume: 3

    Topics: 5-Hydroxytryptophan; Animals; Atropine; Cats; Drug Interactions; Electrodes, Implanted; Electroencephalography; Imipramine; Male; Methiothepin; Mianserin; Reserpine; Serotonin; Time Factors

1976
Induction of purposeless chewing behaviour in rats by 5-HT agonist drugs.
    European journal of pharmacology, 1989, Mar-14, Volume: 162, Issue:1

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Behavior, Animal; Male; Methiothepin; Methoxydimethyltryptamines; Mianserin; Parasympatholytics; Piperazines; Propranolol; Quipazine; Rats; Rats, Inbred Strains; Receptors, Serotonin; Spiperone; Tetrahydronaphthalenes

1989
Effects of 5-HT receptor agonists and antagonists on a reflex response to radiant heat in normal and spinally transected rats.
    Pain, 1982, Volume: 13, Issue:3

    Topics: 5-Hydroxytryptophan; Animals; Carbidopa; Circadian Rhythm; Hot Temperature; Male; Metergoline; Methiothepin; Mianserin; Neurotransmitter Agents; Nociceptors; Rats; Rats, Inbred Strains; Receptors, Serotonin; Reflex; Serotonin; Serotonin Antagonists; Spinal Cord

1982
Effect of methiothepin on imipramine- or mianserin- induced subsensitivity of serotonergic receptors.
    Life sciences, 1982, Mar-08, Volume: 30, Issue:10

    Topics: Animals; Brain; Dibenzazepines; Dibenzothiepins; Imipramine; Kinetics; Male; Methiothepin; Mianserin; Mitochondria; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin

1982
Are 5-hydroxytryptamine7 receptors involved in [3H]5-hydroxytryptamine binding to 5-hydroxytryptamine 1nonA-nonB receptors in rat hypothalamus?
    Molecular pharmacology, 1996, Volume: 49, Issue:3

    Topics: Animals; Binding Sites; Binding, Competitive; Hypothalamus; Kinetics; Male; Methiothepin; Mianserin; Pindolol; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Tritium

1996
Chronic antidepressant exposure enhances 5-hydroxytryptamine7 receptor-mediated cyclic adenosine monophosphate accumulation in rat frontocortical astrocytes.
    The Journal of pharmacology and experimental therapeutics, 1996, Volume: 279, Issue:3

    Topics: Adenylyl Cyclases; Amitriptyline; Animals; Antidepressive Agents; Astrocytes; Cells, Cultured; Cyclic AMP; Cycloheximide; Dactinomycin; Frontal Lobe; Methiothepin; Mianserin; Oligonucleotides, Antisense; Rats; Rats, Wistar; Receptors, Serotonin; RNA, Messenger; Serotonin Antagonists; Signal Transduction

1996
Schistosoma mansoni: effects of serotonin and serotonin receptor antagonists on motility and length of primary sporocysts in vitro.
    Experimental parasitology, 2000, Volume: 94, Issue:4

    Topics: Analysis of Variance; Animals; Carboxylic Acids; Chlorpromazine; Dopamine Antagonists; Dose-Response Relationship, Drug; Indoles; Methiothepin; Mianserin; Movement; Schistosoma mansoni; Serotonin; Serotonin Antagonists; Time Factors; Tryptamines

2000
Antidepressants of the serotonin-antagonist type increase body fat and decrease lifespan of adult Caenorhabditis elegans.
    PloS one, 2008, Volume: 3, Issue:12

    Topics: Adipose Tissue; Animals; Antidepressive Agents; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Longevity; Methiothepin; Mianserin; Obesity; Serotonin; Serotonin Antagonists; Triglycerides

2008