methiothepin and haloperidol

methiothepin has been researched along with haloperidol in 28 studies

Research

Studies (28)

TimeframeStudies, this research(%)All Research%
pre-199010 (35.71)18.7374
1990's7 (25.00)18.2507
2000's4 (14.29)29.6817
2010's6 (21.43)24.3611
2020's1 (3.57)2.80

Authors

AuthorsStudies
Amlaiky, N; Hen, R; Plassat, JL1
Chang, DJ; Eglen, RM; Jasper, JR; Kosaka, A; To, ZP1
Baez, M; Kursar, JD; Lucaites, VL; Nelson, DL; Sasso, DA; Wainscott, DB1
Audinot, V; Chaput, C; Conte, C; Gavaudan, S; Millan, MJ; Newman-Tancredi, A; Touzard, M; Verrièle, L1
Butini, S; Cagnotto, A; Campiani, G; Carminati, P; Castorina, M; Catalanotti, B; Di Cesare, MA; Fattorusso, C; Galletti, B; Gemma, S; Ghirardi, O; Giorgi, G; Goegan, M; Mastroianni, D; Mennini, T; Minetti, P; Nacci, V; Pacifici, L; Scafetta, N; Stasi, MA; Tinti, O1
Andersen, K; Balle, T; Larsen, AK; Liljefors, T; Perregaard, J; Ramirez, MT; Søby, KK1
Glennon, RA1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Bienkowski, P; Bucki, A; Jaśkowska, J; Kazek, G; Kowalski, P; Kołaczkowski, M; Marcinkowska, M; Mierzejewski, P; Mitka, K; Pawłowski, M; Siwek, A; Wasik, A; Wesołowska, A1
Bienkowski, P; Bucki, A; Jastrzębska-Więsek, M; Kazek, G; Kołaczkowski, M; Marcinkowska, M; Mierzejewski, P; Partyka, A; Pawłowski, M; Siwek, A; Śniecikowska, J; Wasik, A; Wesołowska, A1
Bojarski, AJ; Bucki, A; Kazek, G; Kołaczkowski, M; Partyka, A; Pawłowski, M; Satała, G; Siwek, A; Wesołowska, A; Zagórska, A1
Bucki, A; Gryboś, A; Głuch-Lutwin, M; Jastrzębska-Więsek, M; Kołaczkowski, M; Marcinkowska, M; Mierzejewski, P; Partyka, A; Pawłowski, M; Pytka, K; Siwek, A; Śniecikowska, J; Wesołowska, A; Więckowski, K1
Bączek, T; Belka, M; Bojarski, A; Herold, F; Kleps, J; Kozioł, AE; Król, M; Nowak, G; Podsadni, P; Siwek, A; Ślifirski, G; Stachowicz, K; Szewczyk, B; Turło, J1
Bucki, A; Chrzanowska, A; Czopek, A; Drop, M; Głuch-Lutwin, M; Kołaczkowski, M; Partyka, A; Pawłowski, M; Pękala, E; Siwek, A; Struga, M; Wesołowska, A; Zagórska, A1
Bucki, A; Głuch-Lutwin, M; Jakubczyk, M; Jamrozik, M; Jastrzębska-Więsek, M; Kołaczkowski, M; Marcinkowska, M; Mierzejewski, P; Partyka, A; Pawłowski, M; Pytka, K; Siwek, A; Śniecikowska, J; Wesołowska, A; Zagórska, A1
D'amico, DJ; Klawans, HL; Patel, BC1
Glowinski, J; Hamon, M; Herbet, A; Nelson, DL; Pichat, L1
Domino, EF; Hatada, K; Moore, RH1
Burt, DR; Creese, I; Synder, SH1
Eckel, LA; Hargreaves, EL; Penava, D; Vanderwolf, CH; Watson, NV1
Ohno, Y; Warnick, JE1
Cervo, L; Samanin, R1
Dall'Olio, R; Montanaro, N; Vaccheri, A1
Gibb, JW; Hanson, GR; Johnson, M1
Ristine, LA; Spear, LP1
Feigenbaum, JJ; Klawans, HL; Yanai, J1
Hetey, L; Oelssner, W; Schwitzkowsky, R1
Carrillo, AJ; Liu, B; Signs, SA; Wolford, J1

Reviews

1 review(s) available for methiothepin and haloperidol

ArticleYear
Higher-end serotonin receptors: 5-HT(5), 5-HT(6), and 5-HT(7).
    Journal of medicinal chemistry, 2003, Jul-03, Volume: 46, Issue:14

    Topics: Animals; Humans; Ligands; Receptors, Serotonin; Serotonin Agents; Serotonin Antagonists; Serotonin Receptor Agonists

2003

Other Studies

27 other study(ies) available for methiothepin and haloperidol

ArticleYear
Molecular cloning of a mammalian serotonin receptor that activates adenylate cyclase.
    Molecular pharmacology, 1993, Volume: 44, Issue:2

    Topics: Adenylyl Cyclases; Amino Acid Sequence; Animals; Base Sequence; Brain; Cloning, Molecular; Cyclic AMP; DNA; Drosophila; Enzyme Activation; Humans; Intestinal Mucosa; Mice; Molecular Sequence Data; Myocardium; Receptors, Serotonin; Sequence Homology, Amino Acid; Serotonin Antagonists; Serotonin Receptor Agonists

1993
Cloning, expression and pharmacology of a truncated splice variant of the human 5-HT7 receptor (h5-HT7b).
    British journal of pharmacology, 1997, Volume: 122, Issue:1

    Topics: Alternative Splicing; Amino Acid Sequence; Animals; Base Sequence; Cloning, Molecular; Cyclic AMP; DNA, Complementary; Humans; Molecular Sequence Data; Placenta; Radioligand Assay; Rats; Receptors, Serotonin; RNA, Messenger; Sequence Homology, Amino Acid; Sequence Homology, Nucleic Acid

1997
[3H]Rauwolscine: an antagonist radioligand for the cloned human 5-hydroxytryptamine2b (5-HT2B) receptor.
    Naunyn-Schmiedeberg's archives of pharmacology, 1998, Volume: 357, Issue:1

    Topics: Adrenergic alpha-Antagonists; Benzofurans; Binding, Competitive; Cell Line; Cloning, Molecular; Humans; Imidazoles; Radioligand Assay; Receptor, Serotonin, 5-HT2B; Receptors, Serotonin; Serotonin Antagonists; Transfection; Tritium; Yohimbine

1998
Agonist and antagonist actions of antipsychotic agents at 5-HT1A receptors: a [35S]GTPgammaS binding study.
    European journal of pharmacology, 1998, Aug-21, Volume: 355, Issue:2-3

    Topics: Animals; Antipsychotic Agents; CHO Cells; Cricetinae; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Agents; Sulfur Radioisotopes

1998
Pyrrolo[1,3]benzothiazepine-based atypical antipsychotic agents. Synthesis, structure-activity relationship, molecular modeling, and biological studies.
    Journal of medicinal chemistry, 2002, Jan-17, Volume: 45, Issue:2

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Antipsychotic Agents; Behavior, Animal; Brain; Catalepsy; Crystallography, X-Ray; Dopamine; Dopamine Antagonists; Homovanillic Acid; In Vitro Techniques; Male; Mice; Microdialysis; Models, Molecular; Molecular Conformation; Molecular Structure; Prolactin; Pyrroles; Radioligand Assay; Rats; Rats, Inbred F344; Rats, Wistar; Receptors, Dopamine D2; Stereoisomerism; Structure-Activity Relationship; Thiazepines

2002
Synthesis and structure-affinity relationship investigations of 5-heteroaryl-substituted analogues of the antipsychotic sertindole. A new class of highly selective alpha(1) adrenoceptor antagonists.
    Journal of medicinal chemistry, 2003, Jan-16, Volume: 46, Issue:2

    Topics: Adrenergic alpha-Antagonists; Animals; Antipsychotic Agents; Azoles; Brain; Cell Line; Cricetinae; Humans; Imidazoles; In Vitro Techniques; Indoles; Pyridines; Pyrimidines; Radioligand Assay; Rats; Receptors, Adrenergic, alpha-1; Receptors, Dopamine; Receptors, Serotonin; Structure-Activity Relationship; Triazoles

2003
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
Novel arylsulfonamide derivatives with 5-HT₆/5-HT₇ receptor antagonism targeting behavioral and psychological symptoms of dementia.
    Journal of medicinal chemistry, 2014, Jun-12, Volume: 57, Issue:11

    Topics: Animals; Antidepressive Agents; Antipsychotic Agents; Avoidance Learning; Benzoxazoles; Catalepsy; CHO Cells; Cricetulus; Dementia; Dopamine D2 Receptor Antagonists; HEK293 Cells; Humans; Male; Models, Molecular; Motor Activity; Radioligand Assay; Rats, Wistar; Receptors, Serotonin; Serotonin Antagonists; Structure-Activity Relationship; Sulfonamides

2014
Novel 5-HT6 receptor antagonists/D2 receptor partial agonists targeting behavioral and psychological symptoms of dementia.
    European journal of medicinal chemistry, 2015, Mar-06, Volume: 92

    Topics: Animals; Benzamides; Dementia; Dose-Response Relationship, Drug; Drug Partial Agonism; Humans; Indoles; Ligands; Male; Models, Molecular; Molecular Structure; Piperazines; Quinolones; Rats; Rats, Wistar; Receptors, Dopamine D2; Receptors, Serotonin; Structure-Activity Relationship; Swimming

2015
Structure-activity relationships and molecular studies of novel arylpiperazinylalkyl purine-2,4-diones and purine-2,4,8-triones with antidepressant and anxiolytic-like activity.
    European journal of medicinal chemistry, 2015, Jun-05, Volume: 97

    Topics: Animals; Anti-Anxiety Agents; Antidepressive Agents; Binding Sites; Disease Models, Animal; Models, Molecular; Molecular Structure; Piperazine; Piperazines; Purines; Pyrimidinones; Structure-Activity Relationship

2015
Novel 3-(1,2,3,6-Tetrahydropyridin-4-yl)-1H-indole-Based Multifunctional Ligands with Antipsychotic-Like, Mood-Modulating, and Procognitive Activity.
    Journal of medicinal chemistry, 2017, 09-14, Volume: 60, Issue:17

    Topics: Affect; Anti-Anxiety Agents; Antidepressive Agents; Antipsychotic Agents; Dementia; Dopamine Agonists; Drug Design; Humans; Indoles; Ligands; Models, Molecular; Pyridines; Receptors, Dopamine D2; Receptors, Serotonin; Serotonin 5-HT1 Receptor Agonists; Serotonin Antagonists

2017
Synthesis of new 5,6,7,8-tetrahydropyrido[1,2-c]pyrimidine derivatives with rigidized tryptamine moiety as potential SSRI and 5-HT
    European journal of medicinal chemistry, 2019, Oct-15, Volume: 180

    Topics: Animals; Cells, Cultured; Crystallography, X-Ray; Dose-Response Relationship, Drug; HEK293 Cells; Humans; Ligands; Male; Mice; Models, Molecular; Molecular Structure; Pyrimidines; Rats; Receptor, Serotonin, 5-HT1A; RNA-Binding Proteins; Structure-Activity Relationship; Tryptamines

2019
Novel multitarget 5-arylidenehydantoins with arylpiperazinealkyl fragment: Pharmacological evaluation and investigation of cytotoxicity and metabolic stability.
    Bioorganic & medicinal chemistry, 2019, 09-15, Volume: 27, Issue:18

    Topics: Animals; Antidepressive Agents; Depression; Disease Models, Animal; Humans; Receptors, Serotonin; Structure-Activity Relationship

2019
Multifunctional 6-fluoro-3-[3-(pyrrolidin-1-yl)propyl]-1,2-benzoxazoles targeting behavioral and psychological symptoms of dementia (BPSD).
    European journal of medicinal chemistry, 2020, Apr-01, Volume: 191

    Topics: Animals; Antipsychotic Agents; Behavior, Animal; Benzoxazoles; Dementia; Dizocilpine Maleate; Dose-Response Relationship, Drug; Ether-A-Go-Go Potassium Channels; Humans; Male; Mice; Models, Molecular; Molecular Structure; Structure-Activity Relationship

2020
The effect of methysergide on 5-hydroxytryptamine turnover in whole brain.
    The Journal of pharmacy and pharmacology, 1976, Volume: 28, Issue:5

    Topics: Animals; Brain; Guinea Pigs; Haloperidol; Homovanillic Acid; Hydroxyindoleacetic Acid; Male; Methiothepin; Methysergide; Serotonin; Time Factors

1976
In vitro and in vivo disposition of 3H-methiothepin in brain tissues. Relationship to the effects of acute treatment with methiothepin on central serotoninergic receptors.
    Naunyn-Schmiedeberg's archives of pharmacology, 1979, Volume: 310, Issue:1

    Topics: Adenylyl Cyclases; Animals; Brain; Dibenzothiepins; Haloperidol; Male; Membranes; Methiothepin; Rats; Receptors, Serotonin; Serotonin; Spiperone; Synaptosomes; Time Factors

1979
Effects of N,N-dimethyltryptamine on electrically evoked responses in the cat visual system and modification by neuroleptic agents.
    Neuropharmacology, 1976, Volume: 15, Issue:9

    Topics: Animals; Cats; Chlorpromazine; Dibenzothiepins; Dose-Response Relationship, Drug; Drug Interactions; Evoked Potentials; Haloperidol; Methiothepin; N,N-Dimethyltryptamine; Optic Chiasm; Thiothixene; Tranquilizing Agents; Tryptamines; Visual Cortex; Visual Pathways

1976
The dopamine receptor: differential binding of d-LSD and related agents to agonist and antagonist states.
    Life sciences, 1975, Dec-01, Volume: 17, Issue:11

    Topics: Animals; Apomorphine; Binding, Competitive; Cattle; Caudate Nucleus; Cyproheptadine; Dopamine; Fluphenazine; Haloperidol; Lysergic Acid Diethylamide; Methiothepin; Receptors, Drug; Stereoisomerism

1975
Serotonin-dependent cerebral activation: effects of methiothepin and other serotonergic antagonists.
    Brain research, 1992, Nov-27, Volume: 597, Issue:1

    Topics: Animals; Cerebral Cortex; Electrodes; Haloperidol; Hippocampus; Male; Methiothepin; Rats; Rats, Sprague-Dawley; Serotonin; Serotonin Antagonists

1992
Selective depression of the segmental polysynaptic reflex by phencyclidine and its analogs in the rat in vitro: interaction with N-methyl-D-aspartate receptors.
    The Journal of pharmacology and experimental therapeutics, 1990, Volume: 252, Issue:1

    Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Binding Sites; Haloperidol; In Vitro Techniques; Magnesium; Male; Methiothepin; N-Methylaspartate; Phencyclidine; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Reflex; Spinal Cord

1990
Potential antidepressant properties of 8-hydroxy-2-(di-n-propylamino)tetralin, a selective serotonin1A receptor agonist.
    European journal of pharmacology, 1987, Dec-01, Volume: 144, Issue:2

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Drug Interactions; Haloperidol; Male; Methiothepin; Naphthalenes; Physical Exertion; Rats; Receptors, Serotonin; Serotonin; Sulpiride; Swimming; Tetrahydronaphthalenes

1987
Reduced head-twitch response to quipazine of rats previously treated with methiothepin: possible involvement of dopaminergic system.
    Pharmacology, biochemistry, and behavior, 1985, Volume: 23, Issue:1

    Topics: 5-Hydroxytryptophan; Animals; Dibenzothiepins; Haloperidol; Head; Male; Methiothepin; Movement; Quinolines; Quipazine; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Serotonin; Synaptic Transmission

1985
Effects of dopaminergic and serotonergic receptor blockade on neurochemical changes induced by acute administration of methamphetamine and 3,4-methylenedioxymethamphetamine.
    Neuropharmacology, 1988, Volume: 27, Issue:11

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; Animals; Haloperidol; Male; Methamphetamine; Methiothepin; Piperidines; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Serotonin; Ritanserin; Serotonin Antagonists

1988
Suckling behavior in neonatal rats: psychopharmacological investigations.
    Journal of comparative and physiological psychology, 1982, Volume: 96, Issue:2

    Topics: Animals; Animals, Newborn; Haloperidol; Metergoline; Methiothepin; Methysergide; Naloxone; Neurotransmitter Agents; Phentolamine; Propranolol; Rats; Rats, Inbred Strains; Scopolamine; Sucking Behavior

1982
The comparative roles of dopaminergic and serotonergic mechanisms in mediating quipazine induced increases in locomotor activity.
    Journal of neural transmission, 1983, Volume: 57, Issue:1-2

    Topics: Animals; Dopamine; Drug Interactions; Haloperidol; Locomotion; Male; Methiothepin; Methysergide; Motor Activity; Quinolines; Quipazine; Rats; Rats, Inbred Strains; Serotonin

1983
Influence of psychotomimetics and lisuride on synaptosomal dopamine release in the nucleus accumbens of rats.
    European journal of pharmacology, 1983, Sep-30, Volume: 93, Issue:3-4

    Topics: Animals; Dopamine; Ergolines; Hallucinogens; Haloperidol; In Vitro Techniques; Lisuride; Male; Mescaline; Methiothepin; Monoamine Oxidase Inhibitors; Nucleus Accumbens; Rats; Rats, Inbred Strains; Septal Nuclei; Synaptosomes

1983
Serotonergic involvement in the regulation of prolactin and vasoactive intestinal peptide mRNA expression in the rat anterior pituitary.
    Molecular and cellular endocrinology, 1994, Volume: 105, Issue:2

    Topics: 5-Hydroxytryptophan; alpha-Methyltyrosine; Animals; Blotting, Northern; Bromocriptine; Gene Expression Regulation; Haloperidol; Ketanserin; Male; Methiothepin; Methoxydimethyltryptamines; Methyltyrosines; Pituitary Gland, Anterior; Prolactin; Quipazine; Rats; Rats, Sprague-Dawley; RNA, Messenger; Serotonin; Time Factors; Transcription, Genetic; Vasoactive Intestinal Peptide

1994