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methionine sulfoximine and misonidazole

methionine sulfoximine has been researched along with misonidazole in 29 studies

Research

Studies (29)

TimeframeStudies, this research(%)All Research%
pre-199026 (89.66)18.7374
1990's3 (10.34)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Jenner, TJ; Maggi, A; O'Neill, P; Paone, A; Sapora, O1
Cai, RM; Ding, L; Jin, XQ; Jin, YZ; Lu, WQ; Shen, ZF; Xu, JF; Xu, LM; Yang, JK1
Hettiaratchi, P; Koch, CJ; Stobbe, CC1
McNally, NJ; Soranson, JA1
Flaherty, AA; Penney, DP; Siemann, DW1
Astor, MB; Biaglow, JE; Clark, EP; Epp, ER; Hall, EJ; Roizen-Towle, L; Varnes, ME1
Biaglow, JE; Clark, EP; Donahue, LL; Epp, ER; Tuttle, SW; Varnes, ME1
Roizin-Towle, L1
Baer, KA; Koch, CJ; Stobbe, CC1
Abe, M; Komuro, C; Nishidai, T; Ono, K; Shibamoto, Y; Takahashi, M; Tsutsui, K1
Bump, EA; Kovacs, M; Lee, W; Rice, GC; Shrieve, DC1
Astor, M; Tomashefsky, P; White, RD1
Edgren, M; Nishidai, T; Révész, L; Scott, OC1
Edgren, M; Révész, L2
Guichard, M; Lespinasse, F; Malaise, EP1
Scott, OC1
Hodgkiss, RJ; Middleton, RW2
Denekamp, J; Minchinton, AI; Shrieve, DC1
Durand, RE1
Adams, GE1
Brown, JM; Yu, NY1
Palcic, B1
Biaglow, JE; Costello, T; Hall, EJ; Roizin-Towle, L; Varnes, ME1
Abe, M; Edgren, M; Nishidai, T; Ono, K; Révész, L; Takahashi, M1
Denekamp, J; Middleton, RW; Minchinton, AI; Rojas, A; Smith, KA; Soranson, JA1
Biaglow, JE; Clark, EP; Epp, ER; Morse-Gaudio, M; Zachgo, E1
Denekamp, J; Johns, H; Joiner, B; Joiner, M; Stevens, G1

Reviews

2 review(s) available for methionine sulfoximine and misonidazole

ArticleYear
Biochemistry of reduction of nitro heterocycles.
    Biochemical pharmacology, 1986, Jan-01, Volume: 35, Issue:1

    Topics: Animals; Buthionine Sulfoximine; Catalase; Cell Division; Cell Survival; Etanidazole; Free Radicals; Glucose; Glutathione; Glycolysis; Hexosephosphates; Humans; Hypoxia; Methionine Sulfoximine; Microbodies; Microsomes; Misonidazole; Mitochondria; Nitroimidazoles; Oxidation-Reduction; Pentoses; Peroxidases; Sulfhydryl Compounds

1986
In vivo and in vitro mechanisms of radiation sensitization, drug synthesis and screening: can we learn it all from the high dose data?
    International journal of radiation oncology, biology, physics, 1984, Volume: 10, Issue:8

    Topics: Animals; Buthionine Sulfoximine; Cell Survival; Cricetinae; Diamide; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Humans; Maleates; Methionine Sulfoximine; Mice; Misonidazole; Oxygen; Radiation-Sensitizing Agents; Sulfhydryl Compounds

1984

Other Studies

27 other study(ies) available for methionine sulfoximine and misonidazole

ArticleYear
Induction of mutations in V79-4 mammalian cells under hypoxic and aerobic conditions by the cytotoxic 2-nitroimidazole-aziridines, RSU-1069 and RSU-1131. The influence of cellular glutathione.
    Biochemical pharmacology, 1992, Oct-06, Volume: 44, Issue:7

    Topics: Animals; Aziridines; Buthionine Sulfoximine; Cell Hypoxia; Cell Line; Cell Survival; Cricetinae; Cricetulus; Dose-Response Relationship, Drug; Glutathione; Methionine Sulfoximine; Misonidazole; Mutagenicity Tests; Mutation; Oxidation-Reduction; Oxygen; Thioguanine

1992
Effects of glutathione depletion using buthionine sulphoximine on the cytotoxicity in mammalian cells and human tumor cells in vitro.
    Chinese medical journal, 1992, Volume: 105, Issue:8

    Topics: Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Buthionine Sulfoximine; Cell Hypoxia; Cisplatin; Drug Synergism; Fluorouracil; Glutathione; Humans; Leukemia, Erythroblastic, Acute; Methionine Sulfoximine; Misonidazole; Stomach Neoplasms; Tumor Cells, Cultured

1992
Combined radiation-protective and radiation-sensitizing agents. IV: Measurement of intracellular protector concentrations.
    International journal of radiation oncology, biology, physics, 1989, Volume: 16, Issue:4

    Topics: Animals; Ascorbic Acid; Buthionine Sulfoximine; Cell Line; Coenzyme A; Cysteine; Glutathione; Methionine Sulfoximine; Misonidazole; Radiation-Protective Agents; Radiation-Sensitizing Agents

1989
Radiosensitization by misonidazole during recovery of cellular thiols following depletion by BSO or DEM.
    International journal of radiation oncology, biology, physics, 1989, Volume: 16, Issue:5

    Topics: Anaerobiosis; Animals; Buthionine Sulfoximine; Cell Line; Cell Survival; Cricetinae; Glutathione; Maleates; Methionine Sulfoximine; Misonidazole; Radiation-Sensitizing Agents

1989
Effect of thiol manipulation on chemopotentiation by nitroimidazoles.
    International journal of radiation oncology, biology, physics, 1989, Volume: 16, Issue:5

    Topics: Buthionine Sulfoximine; Cell Line; Cell Survival; Cyclophosphamide; Drug Synergism; Glutathione; Humans; Methionine Sulfoximine; Misonidazole; Oxygen

1989
Enhancement in the aerobic toxicity of misonidazole and SR-2508 by buthionine sulfoximine and 4-hydroxypyrazole: the role of hydrogen peroxide.
    International journal of radiation oncology, biology, physics, 1986, Volume: 12, Issue:7

    Topics: Buthionine Sulfoximine; Cell Line; Cell Survival; Etanidazole; Glutathione; Humans; Hydrogen Peroxide; In Vitro Techniques; Methionine Sulfoximine; Misonidazole; Nitroimidazoles; Oxygen; Pyrazoles; Radiation-Sensitizing Agents

1986
Selective enhancement of hypoxic cell killing by melphalan via thiol depletion: in vitro studies with hypoxic cell sensitizers and buthionine sulfoximine.
    Journal of the National Cancer Institute, 1985, Volume: 74, Issue:1

    Topics: Animals; Buthionine Sulfoximine; Cells, Cultured; Cricetinae; Cricetulus; Drug Synergism; Etanidazole; Melphalan; Methionine Sulfoximine; Misonidazole; Nitroimidazoles; Oxygen; Sulfhydryl Compounds

1985
Combined radiation-protective and radiation-sensitizing agents. III: Radiosensitization by misonidazole as a function of concentrations of endogenous glutathione or exogenous thiols.
    International journal of radiation oncology, biology, physics, 1986, Volume: 12, Issue:7

    Topics: Animals; Buthionine Sulfoximine; Cell Line; Cricetinae; Cysteamine; Glutathione; In Vitro Techniques; Methionine Sulfoximine; Misonidazole; Radiation-Sensitizing Agents

1986
Radiosensitizing effect of misonidazole in combination with an inhibitor of glutathione synthesis in murine tumors.
    International journal of radiation oncology, biology, physics, 1986, Volume: 12, Issue:9

    Topics: Animals; Buthionine Sulfoximine; Combined Modality Therapy; Drug Therapy, Combination; Glutathione; Methionine Sulfoximine; Mice; Misonidazole; Neoplasms, Experimental; Radiation-Sensitizing Agents

1986
Quantitative analysis of cellular glutathione by flow cytometry utilizing monochlorobimane: some applications to radiation and drug resistance in vitro and in vivo.
    Cancer research, 1986, Volume: 46, Issue:12 Pt 1

    Topics: Animals; Bridged Bicyclo Compounds; Bridged-Ring Compounds; Buthionine Sulfoximine; Cell Line; Cells, Cultured; Drug Resistance; Flow Cytometry; Fluorescent Dyes; Gene Amplification; Glutathione; Methionine Sulfoximine; Mice; Misonidazole; Oxygen

1986
Relationship between thiol depletion and chemosensitization in a transplantable murine bladder tumor.
    Journal of the National Cancer Institute, 1985, Volume: 74, Issue:6

    Topics: Animals; Buthionine Sulfoximine; Carcinoma, Transitional Cell; Cyclophosphamide; Drug Combinations; Drug Resistance; Female; Glutathione; Liver; Maleates; Methionine Sulfoximine; Mice; Mice, Inbred C3H; Misonidazole; Neoplasm Transplantation; Urinary Bladder Neoplasms

1985
Combined effect of misonidazole and glutathione depletion by buthionine sulphoximine on cellular radiation response.
    International journal of radiation biology and related studies in physics, chemistry, and medicine, 1985, Volume: 47, Issue:4

    Topics: Animals; Buthionine Sulfoximine; Cell Line; Cricetinae; Cricetulus; DNA, Single-Stranded; Dose-Response Relationship, Drug; Fibroblasts; Glutathione; Humans; In Vitro Techniques; Methionine Sulfoximine; Misonidazole; Nitroimidazoles; Radiation Tolerance

1985
Glutathione requirement for the rejoining of radiation-induced DNA breaks in misonidazole-treated cells.
    International journal of radiation biology and related studies in physics, chemistry, and medicine, 1985, Volume: 48, Issue:2

    Topics: Buthionine Sulfoximine; DNA; DNA Repair; DNA, Single-Stranded; Fibroblasts; Glutathione; Humans; Methionine Sulfoximine; Misonidazole; Nitroimidazoles; Radiation-Sensitizing Agents

1985
Influence of buthionine sulfoximine and misonidazole on glutathione level and radiosensitivity of human tumor xenografts.
    Radiation research, 1986, Volume: 105, Issue:1

    Topics: Adenocarcinoma; Animals; Buthionine Sulfoximine; Cell Line; Colonic Neoplasms; Female; Glutathione; Humans; Melanoma; Methionine Sulfoximine; Mice; Mice, Nude; Misonidazole; Neoplasm Transplantation; Neoplasms; Radiation Tolerance; Transplantation, Heterologous

1986
Glutathione depletion: does it influence radiosensitization by misonidazole?
    The British journal of radiology, 1986, Volume: 59, Issue:699

    Topics: Buthionine Sulfoximine; Drug Interactions; Glutathione; Methionine Sulfoximine; Misonidazole

1986
Effects of glutathione depletion using buthionine sulphoximine on the cytotoxicity of nitroaromatic compounds in mammalian cells in vitro.
    Biochemical pharmacology, 1985, Jun-15, Volume: 34, Issue:12

    Topics: Animals; Buthionine Sulfoximine; Cells, Cultured; Cricetinae; Cricetulus; Glutathione; Methionine Sulfoximine; Misonidazole; Nitrofurantoin; Nitroimidazoles

1985
Effects of glutathione depletion by buthionine sulfoximine on radiosensitization by oxygen and misonidazole in vitro.
    Radiation research, 1985, Volume: 102, Issue:3

    Topics: Animals; Buthionine Sulfoximine; Cell Line; Cell Survival; Cricetinae; Cricetulus; Drug Synergism; Glutathione; Mathematics; Methionine Sulfoximine; Misonidazole; Oxygen; Radiation-Sensitizing Agents

1985
Roles of thiols in cellular radiosensitivity.
    International journal of radiation oncology, biology, physics, 1984, Volume: 10, Issue:8

    Topics: Amifostine; Animals; Buthionine Sulfoximine; Cell Line; Cell Survival; Cricetinae; Cricetulus; Methionine Sulfoximine; Misonidazole; Oxygen; Radiation Tolerance; Radiation-Protective Agents; Radiation-Sensitizing Agents; Sulfhydryl Compounds

1984
Radiosensitizers: a conference preview.
    International journal of radiation oncology, biology, physics, 1984, Volume: 10, Issue:8

    Topics: Animals; Aziridines; Buthionine Sulfoximine; Carmustine; Combined Modality Therapy; Drug Synergism; Etanidazole; Humans; Ketones; Lomustine; Maleates; Methionine Sulfoximine; Mice; Misonidazole; Neoplasms; Nitroimidazoles; Radiation-Sensitizing Agents

1984
Depletion of glutathione in vivo as a method of improving the therapeutic ratio of misonidazole and SR 2508.
    International journal of radiation oncology, biology, physics, 1984, Volume: 10, Issue:8

    Topics: Animals; Buthionine Sulfoximine; Combined Modality Therapy; Etanidazole; Glutathione; Maleates; Methionine Sulfoximine; Mice; Mice, Inbred Strains; Misonidazole; Neoplasm Transplantation; Neoplasms, Experimental; Nitroimidazoles; Radiation-Sensitizing Agents

1984
Glutathione-dependent yield and repair of single-strand DNA breaks in irradiated cells.
    The British journal of cancer. Supplement, 1984, Volume: 6

    Topics: Buthionine Sulfoximine; Cell Survival; Cells, Cultured; DNA Repair; DNA, Single-Stranded; Egtazic Acid; Glutathione; Humans; Male; Methionine Sulfoximine; Misonidazole; Oxygen

1984
Chemosensitization: do thiols matter?
    International journal of radiation oncology, biology, physics, 1984, Volume: 10, Issue:9

    Topics: Animals; Antineoplastic Agents; Buthionine Sulfoximine; Cell Line; Cell Survival; Cricetinae; Cricetulus; Dose-Response Relationship, Drug; Drug Synergism; Melphalan; Methionine Sulfoximine; Misonidazole; Oxygen; Radiation-Sensitizing Agents; Sulfhydryl Compounds

1984
[Increased effect of hypoxic cell radiation sensitizers in combination with BSO, a substance depleting the intracellular radioprotective thiols].
    Nihon Gan Chiryo Gakkai shi, 1984, Apr-20, Volume: 19, Issue:3

    Topics: Animals; Buthionine Sulfoximine; Cells, Cultured; Cricetinae; Cricetulus; DNA; Drug Synergism; Methionine Sulfoximine; Misonidazole; Oxygen; Radiation-Sensitizing Agents; Sulfhydryl Compounds

1984
Enhancement of misonidazole radiosensitization by buthionine sulphoximine.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 1984, Volume: 2, Issue:4

    Topics: Animals; Buthionine Sulfoximine; Combined Modality Therapy; Dose-Response Relationship, Radiation; Drug Synergism; Glutathione; Methionine Sulfoximine; Mice; Misonidazole; Neoplasm Transplantation; Neoplasms, Experimental; Nitroimidazoles; Radiation-Sensitizing Agents; Skin

1984
Glutathione depletion, radiosensitization, and misonidazole potentiation in hypoxic Chinese hamster ovary cells by buthionine sulfoximine.
    Radiation research, 1984, Volume: 98, Issue:2

    Topics: Animals; Buthionine Sulfoximine; Cell Survival; Cricetinae; Cricetulus; Dose-Response Relationship, Radiation; Drug Synergism; Female; Glutathione; Methionine Sulfoximine; Misonidazole; Nitroimidazoles; Ovary; Oxygen; Radiation-Sensitizing Agents; Time Factors

1984
Enhancement of misonidazole radiosensitization by an inhibitor of glutathione biosynthesis.
    International journal of radiation biology and related studies in physics, chemistry, and medicine, 1983, Volume: 43, Issue:2

    Topics: Animals; Buthionine Sulfoximine; Cell Line; Cell Survival; Cricetinae; Cricetulus; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Drug Interactions; Glutathione; Methionine Sulfoximine; Misonidazole; Nitroimidazoles; Oxygen; Radiation Tolerance

1983
Radiosensitization of mouse skin by oxygen and depletion of glutathione.
    International journal of radiation oncology, biology, physics, 1995, Sep-30, Volume: 33, Issue:2

    Topics: Animals; Buthionine Sulfoximine; Carbon Dioxide; Cell Hypoxia; Dose-Response Relationship, Radiation; Female; Glutathione; Male; Maleates; Methionine Sulfoximine; Mice; Misonidazole; Oxygen; Oxygen Consumption; Partial Pressure; Radiation-Sensitizing Agents; Skin; Tourniquets

1995