methionine sulfoximine has been researched along with diethyl maleate in 92 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 47 (51.09) | 18.7374 |
1990's | 45 (48.91) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
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Morita, I; Murota, S; Ochi, H | 1 |
Di Giulio, RT; Gallagher, EP; Hasspieler, BM | 1 |
Gemba, M; Kambara, K; Kawai, Y; Suzuki, A; Yamaguchi, T | 1 |
Caldwell, J; Marshall, AD | 1 |
Kampinga, HH; Konings, AW; Peter, B; Wartena, M | 1 |
Bottje, WG; Graupner, WG; Maynard, PM | 1 |
Bellomo, G; Mirabelli, F; Orrenius, S; Richelmi, P; Stivala, L; Vairetti, M | 1 |
Dahm, LJ; Roth, RA | 1 |
Ravindranath, V; Shivakumar, BR | 1 |
Hiraishi, H; Ivey, KJ; Mutoh, H; Ota, S; Razandi, M; Sugimoto, T; Terano, A | 1 |
Cammer, W; Tansey, FA | 1 |
Barnhart-Bott, A; Green, MA | 1 |
Buckley, BJ; Kent, RS; Whorton, AR | 1 |
Freeman, ML; Maines, MD; Meredith, MJ; Saunders, EL | 1 |
Ansari, RA; Berndt, WO; Thakran, RS | 1 |
Huang, HS; Jurima-Romet, M; Paul, CJ; Thomas, BH | 1 |
Eisert, DR; Freeman, ML; Meredith, MJ; Saunders, EL | 1 |
Boyd, MR; Ravindranath, V | 1 |
Drobitch, RK; Kloss, KA; Svensson, CK | 1 |
Jordan, SJ; Kennedy, CH; Maples, KR; Mason, RP | 1 |
Himeno, T; Kuriyama, H; Maeda, M; Neda, H; Niitsu, Y; Tsuji, Y; Watanabe, N; Yamauchi, N | 1 |
Magnusson, T; Pileblad, E | 1 |
Atsmon, J; Freeman, ML; Meredith, MJ; Roberts, LJ; Sweetman, BJ | 1 |
He, XW; Osterloh, J | 1 |
Hinder, RA; Oosthuizen, MM; Stein, HJ | 1 |
Elias, MM; Rodriguez, JV; Torres, AM | 1 |
Clapper, JA; Enger, MD; Kang, YJ | 1 |
Den Boer, PJ; Grootegoed, JA; Mackenbach, P | 1 |
Bekkedal, K; Brunborg, G; Dybing, E; Holme, JA; Nelson, SD; Omichinski, JG; Søderlund, EJ; Trygg, B | 1 |
Linder, RE; Perreault, SD; Slott, VL; Strader, LF | 1 |
McNally, NJ; Soranson, JA | 1 |
Honda, S; Matsuo, M | 1 |
Nederbragt, H | 1 |
Freeman, ML; Meredith, MJ | 1 |
Aza, MJ; Collado, PS; Esteller, A; González, J; Lasierra, J | 1 |
Eaton, DL; Monroe, DH | 1 |
DeGraff, WG; Mitchell, JB | 1 |
Falvey, D; Frenkel, GD | 1 |
Sultatos, LG; Woods, L | 1 |
Freeman, ML; Laszlo, A; Meredith, MJ | 1 |
Timbrell, JA; Tulip, K | 1 |
Bhatt, HS; Combes, B; Lober, SB | 1 |
Roos-Verheij, WS; van der Schans, GP; Vos, O | 1 |
Lohman, PH; Roos-Verheij, WS; van der Schans, GP; Vos, O | 1 |
Jones, K; Perry, TL; Wright, JM; Yong, VW | 1 |
Hodgkiss, RJ; Roberts, IJ; Watts, ME; Woodcock, M | 1 |
Enger, MD; Kang, YJ | 1 |
Lobreau, AU; Szekely, JG | 1 |
Adams, SP; Notides, AC | 1 |
Baggett, JM; Berndt, WO | 1 |
Mandel, LJ; Schnellmann, RG | 1 |
Costa, LG; Murphy, SD | 1 |
Astor, M; Tomashefsky, P; White, RD | 1 |
Konings, AW; Penninga, P | 1 |
Galinsky, RE | 1 |
Egle, PM; Shelton, KR; Todd, JM | 1 |
Aw, TY; Kaplowitz, N; Ookhtens, M; Ren, C | 1 |
Romero, FJ; Sáez, GT; Viña, J | 1 |
Låstbom, T; Ormstad, K; Orrenius, S | 1 |
Durand, RE; Olive, PL | 1 |
Adams, GE | 1 |
Brown, JM; Yu, NY | 1 |
Palcic, B | 1 |
Astor, M; Biaglow, JE; Clark, EP; Epp, ER; Varnes, ME | 1 |
Biaglow, JE; Hall, EJ; Roizin-Towle, L; Varnes, ME | 1 |
Roos-Verhey, WS; van der Schans, GP; Vos, O | 1 |
Mizutani, T; Nomura, H; Tajima, K; Yamamoto, K | 1 |
Mitchell, JB; Russo, A | 1 |
Brezis, M; Epstein, FH; Rosen, S; Silva, P | 1 |
Biaglow, JE; McPherson, S; Mitchell, JB; Russo, A | 1 |
Biaglow, JE; Clark, EP; Epp, ER; Varnes, ME | 1 |
Callahan, KS; Harker, LA; Harlan, JM; Levine, JD; Schwartz, BR | 1 |
Buchmüller-Rouiller, Y; Corrandin, SB; Jongeneel, CV; Mauël, J; Ransijn, A; Schneider, P; Smith, J | 1 |
Estrela, JM; Lasso De la Vega, MC; Navarro, J; Obrador, E; Pellicer, JA | 1 |
Denekamp, J; Johns, H; Joiner, B; Joiner, M; Stevens, G | 1 |
Gardiner, CS; Reed, DJ | 1 |
Mulder, GJ; Pang, KS; Snel, CA | 1 |
Awad, JA; Burk, RF; Hill, KE; Lyons, PR; Morrow, JD | 1 |
Huxtable, RJ; Yan, CC | 1 |
Borroz, KI; Buetler, TM; Eaton, DL | 1 |
Chow, S; Hedley, DW | 1 |
Gopalan-Kriczky, P; Hiruma, S; Lotlikar, PD | 1 |
Atzori, L; Dypbukt, JM; Grafström, RC; Hybbinette, SS; Moldéus, P | 1 |
Buckpitt, A; Cho, M; Hammock, B; Jedrychowski, R | 1 |
Sugiyama, M; Tsuzuki, K | 1 |
Campisi, A; Castorina, C; Di Giacomo, C; Perez-Polo, JR; Renis, M; Russo, A; Sorrenti, V; Vanella, A | 1 |
Fanburg, BL; Hassoun, PM; Thannickal, VJ; White, AC | 1 |
Ewing, JF; Maines, MD | 1 |
Jornot, L; Junod, AF | 1 |
Asensi, M; Estrela, JM; Garcia-España, A; Pallardó, FV; Vina, J | 1 |
Canonico, PL; Sortino, MA | 1 |
Dackiw, AP; Marshall, JC; Nathens, AB; Rotstein, OD; Watson, RW | 1 |
1 review(s) available for methionine sulfoximine and diethyl maleate
Article | Year |
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In vivo and in vitro mechanisms of radiation sensitization, drug synthesis and screening: can we learn it all from the high dose data?
Topics: Animals; Buthionine Sulfoximine; Cell Survival; Cricetinae; Diamide; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Humans; Maleates; Methionine Sulfoximine; Mice; Misonidazole; Oxygen; Radiation-Sensitizing Agents; Sulfhydryl Compounds | 1984 |
91 other study(ies) available for methionine sulfoximine and diethyl maleate
Article | Year |
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Roles of glutathione and glutathione peroxidase in the protection against endothelial cell injury induced by 15-hydroperoxyeicosatetraenoic acid.
Topics: Animals; Antioxidants; Azoles; Buthionine Sulfoximine; Carotid Arteries; Cattle; Cells, Cultured; Endothelium, Vascular; Glutathione; Glutathione Peroxidase; Isoindoles; Kinetics; Leukotrienes; Lipid Peroxides; Maleates; Methionine Sulfoximine; Organoselenium Compounds; Oxidation-Reduction; Pyrrolidonecarboxylic Acid; Selenium; Sodium Selenite; Thiazoles; Thiazolidines | 1992 |
Effects of buthionine sulfoximine and diethyl maleate on glutathione turnover in the channel catfish.
Topics: Animals; Buthionine Sulfoximine; Cytosol; Depression, Chemical; Gills; Glutamate-Cysteine Ligase; Glutathione; Ictaluridae; Liver; Maleates; Methionine Sulfoximine; Mitochondria; Peptidyl Transferases; Starvation; Time Factors | 1992 |
Increases in urinary enzyme excretion in rats depleted of glutathione inhibited by scavenger of oxygen free radicals.
Topics: Acetylglucosaminidase; Animals; Blood Urea Nitrogen; Buthionine Sulfoximine; Cisplatin; Enzymes; Free Radical Scavengers; gamma-Glutamyltransferase; Glutathione; Kidney Cortex; Male; Maleates; Methionine Sulfoximine; Oxygen Consumption; Rats; Rats, Sprague-Dawley; Thiourea | 1992 |
Influence of modulators of epoxide metabolism on the cytotoxicity of trans-anethole in freshly isolated rat hepatocytes.
Topics: Allylbenzene Derivatives; Animals; Anisoles; Antimetabolites; Buthionine Sulfoximine; Cell Survival; Cells, Cultured; Chalcone; Chalcones; Cyclohexanes; Cyclohexenes; Dose-Response Relationship, Drug; Epoxide Hydrolases; Epoxy Compounds; Female; Flavoring Agents; Glutathione; L-Lactate Dehydrogenase; Liver; Maleates; Methionine Sulfoximine; Rats; Rats, Inbred Strains; Trichloroepoxypropane | 1992 |
Role of lipid peroxidation and DNA damage in paraquat toxicity and the interaction of paraquat with ionizing radiation.
Topics: Animals; Buthionine Sulfoximine; Cell Line; Cell Membrane; Cell Survival; DNA Damage; Dose-Response Relationship, Drug; Fatty Acids; Lipid Peroxidation; Liver; Male; Maleates; Methionine Sulfoximine; Mice; Mice, Inbred C57BL; Paraquat; Radiation Dosage; Radiation-Sensitizing Agents; Temperature; Tumor Cells, Cultured; Vitamin E | 1992 |
Effect of glutathione depletion on tissue and plasma prostacyclin and thromboxane in rats.
Topics: Animals; Buthionine Sulfoximine; Epoprostenol; Glutathione; Kidney; Liver; Lung; Male; Maleates; Methionine Sulfoximine; Methylcholanthrene; Rats; Rats, Inbred Strains; Thromboxane B2 | 1992 |
Demonstration of nuclear compartmentalization of glutathione in hepatocytes.
Topics: Animals; Bridged Bicyclo Compounds; Buthionine Sulfoximine; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Cell Nucleus; Cells, Cultured; Cytosol; Ethylmaleimide; Fluorescein-5-isothiocyanate; Fluorescent Dyes; Glutathione; Kinetics; Liver; Male; Maleates; Methionine Sulfoximine; Pyrazoles; Rats; Rats, Inbred Strains; Spectrometry, Fluorescence; Subcellular Fractions; Vitamin K | 1992 |
Protection against alpha-naphthylisothiocyanate-induced liver injury by decreased hepatic non-protein sulfhydryl content.
Topics: 1-Naphthylisothiocyanate; Animals; Aspartate Aminotransferases; Bile; Bile Acids and Salts; Bilirubin; Buthionine Sulfoximine; Cholestasis, Intrahepatic; gamma-Glutamyltransferase; Glutathione; Ketones; Liver; Male; Maleates; Methionine Sulfoximine; Rats; Rats, Inbred Strains | 1991 |
Selective modulation of glutathione in mouse brain regions and its effect on acrylamide-induced neurotoxicity.
Topics: Acrylamides; Animals; Brain; Buthionine Sulfoximine; Drug Interactions; Female; Glutathione; Glyceraldehyde-3-Phosphate Dehydrogenases; Injections, Spinal; Liver; Maleates; Methionine Sulfoximine; Mice; Pyrrolidonecarboxylic Acid; Thiazoles; Thiazolidines | 1992 |
Antioxidant defenses of cultured gastric cells against oxygen metabolites: role of GSH redox cycle and endogenous catalase.
Topics: Animals; Antimetabolites; Buthionine Sulfoximine; Carmustine; Catalase; Cells, Cultured; Chromium; Female; Gastric Mucosa; Glucose; Glucose Oxidase; Glutathione; Glutathione Reductase; Hydrogen Peroxide; Lipid Peroxidation; Male; Maleates; Methionine Sulfoximine; Oxidation-Reduction; Oxygen; Rats; Rats, Inbred Strains | 1991 |
Depletion of glutathione interferes with induction of glycerolphosphate dehydrogenase in the brains of young rats.
Topics: Aging; Animals; Antimetabolites; Brain; Buthionine Sulfoximine; Cyclohexanones; Enzyme Induction; Glutathione; Glutathione Transferase; Glycerolphosphate Dehydrogenase; Hydrocortisone; Immunohistochemistry; Isoenzymes; Maleates; Methionine Sulfoximine; Neuroglia; Rats; Rats, Inbred Strains | 1991 |
The effects of glutathione depletion on the biodistribution of Cu(PTSM) in rats.
Topics: Animals; Antipyrine; Buthionine Sulfoximine; Copper Radioisotopes; Glutathione; Iodine Radioisotopes; Male; Maleates; Methionine Sulfoximine; Organometallic Compounds; Radiation-Protective Agents; Rats; Rats, Inbred Strains; Thiosemicarbazones; Tissue Distribution | 1991 |
Regulation of endothelial cell prostaglandin synthesis by glutathione.
Topics: Animals; Antimetabolites; Buthionine Sulfoximine; Cells, Cultured; Dinitrochlorobenzene; Endothelium, Vascular; Glutathione; Kinetics; Maleates; Methionine Sulfoximine; Prostaglandins; Swine | 1991 |
Enhancement of heme oxygenase-1 synthesis by glutathione depletion in Chinese hamster ovary cells.
Topics: Animals; Antimetabolites; Blotting, Western; Buthionine Sulfoximine; Cadmium; Cadmium Chloride; Cell Line; Cricetinae; Cricetulus; Electrophoresis, Gel, Two-Dimensional; Electrophoresis, Polyacrylamide Gel; Female; Glutathione; Heat-Shock Proteins; Heme Oxygenase (Decyclizing); Kinetics; Maleates; Methionine Sulfoximine; Molecular Weight; Ovary | 1991 |
Effects of mercuric chloride on renal plasma membrane function after depletion or elevation of renal glutathione.
Topics: Animals; Basement Membrane; Biological Transport; Buthionine Sulfoximine; Cell Membrane; Drug Synergism; Glucose; Glutathione; Kidney; Male; Maleates; Mercuric Chloride; Methionine Sulfoximine; p-Aminohippuric Acid; Rats; Rats, Inbred Strains | 1991 |
Enalapril cytotoxicity in primary cultures of rat hepatocytes. II. Role of glutathione.
Topics: Acetylcysteine; Animals; Antimetabolites; Buthionine Sulfoximine; Cell Survival; Cells, Cultured; Drug Synergism; Enalapril; Glutathione; Glutathione Reductase; Glutathione Transferase; L-Lactate Dehydrogenase; Liver; Male; Maleates; Methionine Sulfoximine; Rats; Rats, Inbred F344 | 1991 |
Depletion of glutathione after gamma irradiation modifies survival.
Topics: Animals; Antimetabolites; Buthionine Sulfoximine; Cell Line; Cell Survival; Dose-Response Relationship, Radiation; Gamma Rays; Glutathione; Maleates; Methionine Sulfoximine | 1991 |
Effect of modulators of glutathione synthesis on the hepatotoxicity of 2-methylfuran.
Topics: Alanine Transaminase; Animals; Antimetabolites; Buthionine Sulfoximine; Chemical and Drug Induced Liver Injury; Cystine; Drug Interactions; Furans; Glutathione; Male; Maleates; Methionine Sulfoximine; Pyrrolidonecarboxylic Acid; Rats; Rats, Inbred Strains; Thiazoles; Thiazolidines | 1991 |
Effect of glutathione depletion on the in vivo inhibition of drug metabolism by agents forming an inactive cytochrome P-450 Fe(II):metabolite complex. Studies with amiodarone and troleandomycin.
Topics: Amiodarone; Animals; Antimetabolites; Antipyrine; Buthionine Sulfoximine; Cytochrome P-450 Enzyme System; Glutathione; Liver; Male; Maleates; Methionine Sulfoximine; Pharmaceutical Preparations; Rats; Rats, Inbred Strains; Troleandomycin | 1991 |
In vivo thiyl free radical formation from hemoglobin following administration of hydroperoxides.
Topics: Animals; Buthionine Sulfoximine; Cyclic N-Oxides; Electron Spin Resonance Spectroscopy; Erythrocytes; Free Radicals; Glutathione; Hemoglobins; Iodoacetamide; Male; Maleates; Methionine Sulfoximine; Peroxides; Rats; Rats, Inbred Strains; Spin Labels; Sulfides; tert-Butylhydroperoxide | 1990 |
Suppressive effects of intracellular glutathione on hydroxyl radical production induced by tumor necrosis factor.
Topics: Animals; Antimetabolites; Buthionine Sulfoximine; Cattle; Glutathione; Humans; Hydroxides; Hydroxyl Radical; Intracellular Fluid; Maleates; Methionine Sulfoximine; Mice; Neoplasms, Experimental; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1990 |
Effective depletion of glutathione in rat striatum and substantia nigra by L-buthionine sulfoximine in combination with 2-cyclohexene-1-one.
Topics: Animals; Buthionine Sulfoximine; Corpus Striatum; Cyclohexanones; Glutathione; Male; Maleates; Methionine Sulfoximine; Rats; Rats, Inbred Strains; Substantia Nigra | 1990 |
Conjugation of 9-deoxy-delta 9,delta 12(E)-prostaglandin D2 with intracellular glutathione and enhancement of its antiproliferative activity by glutathione depletion.
Topics: Animals; Antimetabolites; Antineoplastic Agents; Biological Transport; Biotransformation; Buthionine Sulfoximine; Cell Division; Cell Line; Glutathione; Maleates; Mass Spectrometry; Methionine Sulfoximine; Prostaglandin D2; Tritium | 1990 |
Effects of 1,3-dichloropropene on the kidney of Fisher 344 rats after pretreatment with diethyl maleate, buthionine sulfoximine, and aminooxyacetic acid.
Topics: Acetates; Acetylglucosaminidase; Allyl Compounds; Aminooxyacetic Acid; Animals; Antinematodal Agents; Buthionine Sulfoximine; Dose-Response Relationship, Drug; Hydrocarbons, Chlorinated; Kidney; Male; Maleates; Methionine Sulfoximine; Phosphorus; Proteins; Rats; Rats, Inbred F344 | 1990 |
Gastric mucosal injury caused by hemorrhagic shock and reperfusion: protective role of the antioxidant glutathione.
Topics: Animals; Antimetabolites; Blood Transfusion; Buthionine Sulfoximine; Gastric Mucosa; Glutathione; Ischemia; Male; Maleates; Methionine Sulfoximine; Pyloric Antrum; Rats; Rats, Inbred Strains; Reperfusion Injury; Shock, Hemorrhagic; Stomach | 1990 |
Rat kidney function related to tissue glutathione levels. Effects of different glutathione depletors.
Topics: Animals; Buthionine Sulfoximine; Dose-Response Relationship, Drug; Glutamate-Cysteine Ligase; Glutathione; Kidney; Male; Maleates; Methionine Sulfoximine; Rats; Rats, Inbred Strains | 1989 |
Enhanced cadmium cytotoxicity in A549 cells with reduced glutathione levels is due to neither enhanced cadmium accumulation nor reduced metallothionein synthesis.
Topics: Buthionine Sulfoximine; Cadmium; Glutathione; Humans; Lung Neoplasms; Maleates; Metallothionein; Methionine Sulfoximine; Sulfur Radioisotopes; Tumor Cells, Cultured | 1989 |
Glutathione metabolism in cultured Sertoli cells and spermatogenic cells from hamsters.
Topics: Animals; Antimetabolites; Buthionine Sulfoximine; Cells, Cultured; Cricetinae; Glutathione; Male; Maleates; Mesocricetus; Methionine Sulfoximine; Sertoli Cells; Spermatids; Spermatocytes | 1989 |
Different mechanisms are involved in DNA damage, bacterial mutagenicity and cytotoxicity induced by 1,2-dibromo-3-chloropropane in suspensions of rat liver cells.
Topics: Animals; Biotransformation; Buthionine Sulfoximine; Cell Survival; DNA; DNA Damage; Dose-Response Relationship, Drug; Glutathione; In Vitro Techniques; Liver; Maleates; Methionine Sulfoximine; Mutagenicity Tests; Mutation; Propane; Rats; Salmonella typhimurium; Time Factors | 1989 |
Unilateral depletion of testicular glutathione levels in the rat following intratesticular injections of diethylmaleate and buthionine sulfoximine.
Topics: Animals; Buthionine Sulfoximine; Glutathione; Male; Maleates; Methionine Sulfoximine; Rats; Rats, Inbred Strains; Testis | 1989 |
Radiosensitization by misonidazole during recovery of cellular thiols following depletion by BSO or DEM.
Topics: Anaerobiosis; Animals; Buthionine Sulfoximine; Cell Line; Cell Survival; Cricetinae; Glutathione; Maleates; Methionine Sulfoximine; Misonidazole; Radiation-Sensitizing Agents | 1989 |
Protective effect of glutathione against oxygen-induced growth inhibition of human diploid fibroblasts.
Topics: Buthionine Sulfoximine; Cell Division; Cells, Cultured; Culture Media; Fibroblasts; Glutathione; Humans; Maleates; Methionine Sulfoximine; Oxygen | 1989 |
Effect of the glutathione-depleting agents diethylmaleate, phorone and buthionine sulfoximine on biliary copper excretion in rats.
Topics: Animals; Bile; Buthionine Sulfoximine; Copper; Glutathione; Ketones; Male; Maleates; Methionine Sulfoximine; Rats; Rats, Inbred Strains | 1989 |
Glutathione conjugation and induction of a 32,000 dalton stress protein.
Topics: Animals; Buthionine Sulfoximine; Cell Line; Cricetinae; Dose-Response Relationship, Drug; Electrophoresis, Gel, Two-Dimensional; Glutathione; Heat-Shock Proteins; Maleates; Methionine Sulfoximine; Molecular Weight | 1989 |
Inhibition of fibrinolysis by cellular glutathione depletion in the rabbit.
Topics: Animals; Aorta, Thoracic; Buthionine Sulfoximine; Endothelium, Vascular; Fibrinolysis; Glutathione; Injections, Intraperitoneal; Male; Maleates; Methionine Sulfoximine; Rabbits | 1989 |
Effects of modulation of hepatic glutathione on biotransformation and covalent binding of aflatoxin B1 to DNA in the mouse.
Topics: Aflatoxin B1; Aflatoxins; Animals; Bile; Biotransformation; Buthionine Sulfoximine; Butylated Hydroxyanisole; DNA; Epoxy Compounds; Glutathione; Glutathione Transferase; In Vitro Techniques; Liver; Male; Maleates; Methionine Sulfoximine; Mice | 1988 |
Glutathione dependence of neocarzinostatin cytotoxicity and mutagenicity in Chinese hamster V-79 cells.
Topics: Animals; Antibiotics, Antineoplastic; Biotransformation; Buthionine Sulfoximine; Cricetinae; Cricetulus; Glutathione; Maleates; Methionine Sulfoximine; Mutagens; Zinostatin | 1985 |
Evidence for the involvement of sulfhydryl compounds in the inhibition of cellular DNA synthesis by selenite.
Topics: Buthionine Sulfoximine; Cell Nucleus; DNA; HeLa Cells; Humans; In Vitro Techniques; Maleates; Methionine Sulfoximine; Selenious Acid; Selenium; Sulfhydryl Compounds | 1988 |
The role of glutathione in the detoxification of the insecticides methyl parathion and azinphos-methyl in the mouse.
Topics: Animals; Azinphosmethyl; Buthionine Sulfoximine; Glutathione; Inactivation, Metabolic; Insecticides; Liver; Maleates; Methionine Sulfoximine; Methyl Parathion; Mice; Parathion | 1988 |
Depletion of glutathione, heat shock protein synthesis, and the development of thermotolerance in Chinese hamster ovary cells.
Topics: Animals; Buthionine Sulfoximine; Cell Line; Cricetinae; Cricetulus; Electrophoresis, Polyacrylamide Gel; Female; Glutathione; Heat-Shock Proteins; Hot Temperature; Maleates; Methionine Sulfoximine; Molecular Weight; Ovary; Time Factors | 1988 |
Comparative hepatotoxicity and metabolism of N-methylformamide in rats and mice.
Topics: Animals; Buthionine Sulfoximine; Carbon Radioisotopes; Formamides; Glutathione; Liver; Male; Maleates; Methionine Sulfoximine; Mice; Mice, Inbred BALB C; Rats; Rats, Inbred Strains; Species Specificity; Sulfhydryl Compounds | 1988 |
Effect of glutathione depletion on aminopyrine and formaldehyde metabolism.
Topics: Aminopyrine; Aminopyrine N-Demethylase; Animals; Breath Tests; Buthionine Sulfoximine; Formaldehyde; Formates; Glutathione; Ketones; Male; Maleates; Methionine Sulfoximine; Microsomes, Liver; Rats; Rats, Inbred Strains | 1988 |
Reduction of intracellular glutathione content and radiosensitivity.
Topics: Animals; Buthionine Sulfoximine; Cell Line; Cell Survival; Cricetinae; Cricetulus; DNA Repair; Glutathione; HeLa Cells; Humans; In Vitro Techniques; Maleates; Methionine Sulfoximine; Radiation Tolerance | 1986 |
The influence of oxygen on the induction of radiation damage in DNA in mammalian cells after sensitization by intracellular glutathione depletion.
Topics: Animals; Buthionine Sulfoximine; Cell Line; Cell Survival; DNA; Glutathione; Humans; Maleates; Methionine Sulfoximine; Oxygen; Radiation-Sensitizing Agents | 1986 |
Manipulation of glutathione contents fails to alter dopaminergic nigrostriatal neurotoxicity of N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) in the mouse.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Brain Stem; Buthionine Sulfoximine; Butylated Hydroxyanisole; Corpus Striatum; Dopamine; Glutathione; Glutathione Transferase; Liver; Maleates; Methionine Sulfoximine; Mice; Mice, Inbred C57BL; Pyridines; Substantia Nigra | 1986 |
Rapid-mixing studies of radiosensitivity with thiol-depleted mammalian cells.
Topics: Animals; Buthionine Sulfoximine; Cell Line; Cricetinae; Ethylmaleimide; Maleates; Mercaptoethanol; Methionine Sulfoximine; Oxygen; Radiation Tolerance; Radiation-Protective Agents; Sulfhydryl Compounds | 1987 |
Effect of cellular glutathione depletion on cadmium-induced cytotoxicity in human lung carcinoma cells.
Topics: Buthionine Sulfoximine; Cadmium; Cell Survival; Glutathione; Humans; Lung Neoplasms; Maleates; Methionine Sulfoximine; Tumor Cells, Cultured | 1987 |
The effect of glutathione depletion by diamide, diethyl maleate or buthione sulfoximine on the surface structure of mouse L-cells.
Topics: Animals; Azo Compounds; Buthionine Sulfoximine; Cell Membrane; Diamide; Glutathione; L Cells; Maleates; Methionine Sulfoximine; Mice; Microscopy, Electron; Microscopy, Electron, Scanning | 1987 |
Glutathione protection against irreversible binding of diethylstilbestrol in the hamster renal cortex.
Topics: Animals; Buthionine Sulfoximine; Cricetinae; Diethylstilbestrol; Glutathione; In Vitro Techniques; Kidney Cortex; Male; Maleates; Mesocricetus; Methionine Sulfoximine | 1987 |
The effect of depletion of nonprotein sulfhydryls by diethyl maleate plus buthionine sulfoximine on renal uptake of mercury in the rat.
Topics: Animals; Buthionine Sulfoximine; Drug Interactions; In Vitro Techniques; Kidney; Kidney Cortex; Lactates; Lactic Acid; Liver; Male; Maleates; Mercury; Methionine Sulfoximine; p-Aminohippuric Acid; Rats; Rats, Inbred Strains; Sulfhydryl Compounds; Tetraethylammonium; Tetraethylammonium Compounds | 1986 |
Multiple effects of presumed glutathione depletors on rabbit proximal tubules.
Topics: Animals; Buthionine Sulfoximine; Culture Techniques; Cyclohexanones; Female; Glutathione; Ketones; Kidney Concentrating Ability; Kidney Tubules, Proximal; L-Lactate Dehydrogenase; Maleates; Methionine Sulfoximine; Oxygen Consumption; Rabbits | 1986 |
Effect of diethylmaleate and other glutathione depletors on protein synthesis.
Topics: Animals; Body Temperature; Brain; Buthionine Sulfoximine; Glutathione; Ketones; Liver; Male; Maleates; Methionine Sulfoximine; Mice; Protein Biosynthesis | 1986 |
Relationship between thiol depletion and chemosensitization in a transplantable murine bladder tumor.
Topics: Animals; Buthionine Sulfoximine; Carcinoma, Transitional Cell; Cyclophosphamide; Drug Combinations; Drug Resistance; Female; Glutathione; Liver; Maleates; Methionine Sulfoximine; Mice; Mice, Inbred C3H; Misonidazole; Neoplasm Transplantation; Urinary Bladder Neoplasms | 1985 |
On the importance of the level of glutathione and the activity of the pentose phosphate pathway in heat sensitivity and thermotolerance.
Topics: Animals; Buthionine Sulfoximine; Carcinoma, Ehrlich Tumor; Cell Line; Cell Survival; Fibroblasts; Glutathione; Hot Temperature; Maleates; Methionine Sulfoximine; Mice; Pentose Phosphate Pathway; Sulfhydryl Compounds | 1985 |
Role of glutathione turnover in drug sulfation: differential effects of diethylmaleate and buthionine sulfoximine on the pharmacokinetics of acetaminophen in the rat.
Topics: Acetaminophen; Animals; Buthionine Sulfoximine; Glutathione; Kidney; Kinetics; Male; Maleates; Metabolic Clearance Rate; Methionine Sulfoximine; Rats; Rats, Inbred Strains; Sulfates | 1986 |
Evidence that glutathione participates in the induction of a stress protein.
Topics: Buthionine Sulfoximine; Dinitrochlorobenzene; Ethylmaleimide; Glutathione; Heat-Shock Proteins; Maleates; Methionine Sulfoximine; Molecular Weight | 1986 |
Kinetics of glutathione efflux from isolated rat hepatocytes.
Topics: Animals; Buthionine Sulfoximine; Glutathione; Kinetics; Liver; Male; Maleates; Methionine Sulfoximine; Osmolar Concentration; Rats; Rats, Inbred Strains; Temperature | 1986 |
Effects of glutathione depletion on gluconeogenesis in isolated hepatocytes.
Topics: Adenosine Triphosphate; Animals; Buthionine Sulfoximine; Cell Survival; Gluconeogenesis; Glutathione; Glycerophosphates; Ketones; Liver; Malates; Maleates; Malondialdehyde; Methionine Sulfoximine; Rats; Urea | 1985 |
Translocation of amino acids and glutathione studied with the perfused kidney and isolated renal cells.
Topics: Amino Acids; Animals; Borates; gamma-Glutamyltransferase; Glutamate-Cysteine Ligase; Glutathione; In Vitro Techniques; Kidney; Kidney Tubules; Male; Maleates; Methionine Sulfoximine; Rats; Serine; Ureter | 1980 |
Flow cytometry techniques for studying cellular thiols.
Topics: Animals; Buthionine Sulfoximine; Cell Survival; Cricetinae; Cricetulus; Flow Cytometry; Fumarates; Glutathione; Lung; Maleates; Methionine Sulfoximine; Oxygen; Radiation Tolerance; Staining and Labeling; Sulfhydryl Compounds; Sulfhydryl Reagents | 1983 |
Radiosensitizers: a conference preview.
Topics: Animals; Aziridines; Buthionine Sulfoximine; Carmustine; Combined Modality Therapy; Drug Synergism; Etanidazole; Humans; Ketones; Lomustine; Maleates; Methionine Sulfoximine; Mice; Misonidazole; Neoplasms; Nitroimidazoles; Radiation-Sensitizing Agents | 1984 |
Depletion of glutathione in vivo as a method of improving the therapeutic ratio of misonidazole and SR 2508.
Topics: Animals; Buthionine Sulfoximine; Combined Modality Therapy; Etanidazole; Glutathione; Maleates; Methionine Sulfoximine; Mice; Mice, Inbred Strains; Misonidazole; Neoplasm Transplantation; Neoplasms, Experimental; Nitroimidazoles; Radiation-Sensitizing Agents | 1984 |
Factors involved in depletion of glutathione from A549 human lung carcinoma cells: implications for radiotherapy.
Topics: Buthionine Sulfoximine; Cell Line; Cell Survival; Dose-Response Relationship, Radiation; Glutathione; Humans; Lung Neoplasms; Maleates; Methionine Sulfoximine; Radiation-Sensitizing Agents; Time Factors | 1984 |
Depletion of intracellular GSH and NPSH by buthionine sulfoximine and diethyl maleate: factors that influence enhancement of aerobic radiation response.
Topics: Aerobiosis; Buthionine Sulfoximine; Cell Line; Cell Survival; Dose-Response Relationship, Radiation; Glutathione; Humans; Lung Neoplasms; Maleates; Methionine Sulfoximine; Radiation-Sensitizing Agents; Sulfhydryl Compounds; Time Factors | 1984 |
Effects of BSO and DEM on thiol-level and radiosensitivity in HeLa cells.
Topics: Buthionine Sulfoximine; Cell Survival; DNA Repair; DNA, Neoplasm; Dose-Response Relationship, Radiation; HeLa Cells; Humans; Maleates; Methionine Sulfoximine; Radiation-Sensitizing Agents; Sulfhydryl Compounds | 1984 |
Modification of butylated hydroxytoluene-induced pulmonary toxicity in mice by diethyl maleate, buthionine sulfoximine, and cysteine.
Topics: Animals; Body Weight; Buthionine Sulfoximine; Butylated Hydroxytoluene; Cysteine; Drug Synergism; Glutathione; Liver; Lung; Male; Maleates; Methionine Sulfoximine; Mice; Organ Size | 1984 |
Thiols, thiol depletion, and thermosensitivity.
Topics: Acetylcysteine; Animals; Buthionine Sulfoximine; Cell Survival; Cells, Cultured; Cricetinae; Cysteine; Glutathione; Heat-Shock Proteins; Hot Temperature; Maleates; Methionine Sulfoximine; Oxidation-Reduction; Oxygen Consumption; Protein Biosynthesis; Sulfhydryl Compounds; Time Factors | 1983 |
Selective glutathione depletion on function and structure of the isolated perfused rat kidney.
Topics: Amino Acids; Animals; Buthionine Sulfoximine; Cyclohexanones; Glomerular Filtration Rate; Glucose; Glutathione; Kidney; Kidney Concentrating Ability; Loop of Henle; Male; Maleates; Methionine Sulfoximine; Natriuresis; Perfusion; Rats; Rats, Inbred Strains | 1983 |
Cellular glutathione depletion by diethyl maleate or buthionine sulfoximine: no effect of glutathione depletion on the oxygen enhancement ratio.
Topics: Animals; Buthionine Sulfoximine; Carcinoma; Cell Line; Cells, Cultured; Cricetinae; Dose-Response Relationship, Radiation; Glutathione; Humans; Hypoxia; Lung; Lung Neoplasms; Maleates; Methionine Sulfoximine; Oxygen Consumption; Radiation-Sensitizing Agents; Time Factors | 1983 |
The role of thiols in cellular response to radiation and drugs.
Topics: Animals; Azo Compounds; Buthionine Sulfoximine; Cell Survival; Cells, Cultured; Chemical Phenomena; Chemistry; Cricetinae; Diamide; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Female; Glutathione; Humans; Lung Neoplasms; Maleates; Methionine Sulfoximine; Ovary; Oxygen; Radiation-Sensitizing Agents; Sulfhydryl Compounds | 1983 |
Glutathione redox cycle protects cultured endothelial cells against lysis by extracellularly generated hydrogen peroxide.
Topics: Animals; Blood Vessels; Buthionine Sulfoximine; Carmustine; Cattle; Cells, Cultured; Dinitrochlorobenzene; Endothelium; Glutathione; Glutathione Peroxidase; Glutathione Reductase; Humans; Hydrogen Peroxide; Maleates; Methionine Sulfoximine; Oxidation-Reduction | 1984 |
Role of glutathione in macrophage activation: effect of cellular glutathione depletion on nitrite production and leishmanicidal activity.
Topics: Amino Acid Oxidoreductases; Animals; Buthionine Sulfoximine; Cells, Cultured; Enzyme Inhibitors; Female; Glutathione; Leishmaniasis; Macrophage Activation; Male; Maleates; Methionine Sulfoximine; Mice; Mice, Inbred CBA; Nitric Oxide; Nitric Oxide Synthase; Nitrites; RNA, Messenger | 1995 |
Elimination of Ehrlich tumours by ATP-induced growth inhibition, glutathione depletion and X-rays.
Topics: Adenosine Triphosphate; Animals; Antineoplastic Agents; Buthionine Sulfoximine; Carcinoma, Ehrlich Tumor; Cell Division; Combined Modality Therapy; Enzyme Inhibitors; Glutamate-Cysteine Ligase; Glutathione; Hydrogen-Ion Concentration; Male; Maleates; Methionine Sulfoximine; Mice; Radiation-Sensitizing Agents; X-Rays | 1995 |
Radiosensitization of mouse skin by oxygen and depletion of glutathione.
Topics: Animals; Buthionine Sulfoximine; Carbon Dioxide; Cell Hypoxia; Dose-Response Relationship, Radiation; Female; Glutathione; Male; Maleates; Methionine Sulfoximine; Mice; Misonidazole; Oxygen; Oxygen Consumption; Partial Pressure; Radiation-Sensitizing Agents; Skin; Tourniquets | 1995 |
Synthesis of glutathione in the preimplantation mouse embryo.
Topics: Animals; Antimetabolites; Blastocyst; Buthionine Sulfoximine; Culture Media; Cycloheximide; Cystine; Female; Glutathione; In Vitro Techniques; Maleates; Methionine; Methionine Sulfoximine; Mice; Pregnancy | 1995 |
Glutathione conjugation of bromosulfophthalein in relation to hepatic glutathione content in the rat in vivo and in the perfused rat liver.
Topics: Animals; Buthionine Sulfoximine; Glutathione; Infusions, Intravenous; Liver; Male; Maleates; Methionine Sulfoximine; Perfusion; Rats; Rats, Wistar; Sulfobromophthalein | 1995 |
Liver and kidney necrosis in selenium-deficient rats depleted of glutathione.
Topics: Animals; Buthionine Sulfoximine; Dinoprost; Glutathione; Ketones; Kidney; Lipid Peroxides; Liver; Male; Maleates; Methionine Sulfoximine; Necrosis; Osmolar Concentration; Proteins; Rats; Rats, Sprague-Dawley; Selenium; Selenoprotein P; Selenoproteins | 1995 |
Relationship between glutathione concentration and metabolism of the pyrrolizidine alkaloid, monocrotaline, in the isolated, perfused liver.
Topics: Analysis of Variance; Animals; Antimetabolites, Antineoplastic; Bile; Buthionine Sulfoximine; Ethylene Chlorohydrin; Glutathione; Liver; Male; Maleates; Methionine Sulfoximine; Monocrotaline; Perfusion; Pyrroles; Pyrrolidonecarboxylic Acid; Rats; Rats, Sprague-Dawley; Thiazoles; Thiazolidines | 1995 |
Modulation of gamma-glutamylcysteine synthetase large subunit mRNA expression by butylated hydroxyanisole.
Topics: Animals; Base Sequence; Buthionine Sulfoximine; Butylated Hydroxyanisole; Diet; DNA, Complementary; Fasting; Gene Expression Regulation, Enzymologic; Glutamate-Cysteine Ligase; Glutathione; Ketones; Liver; Male; Maleates; Methionine Sulfoximine; Mice; Mice, Inbred Strains; Molecular Sequence Data; RNA, Messenger | 1994 |
Evaluation of methods for measuring cellular glutathione content using flow cytometry.
Topics: Animals; Breast Neoplasms; Bridged Bicyclo Compounds; Buthionine Sulfoximine; Carcinoma; Carcinosarcoma; CHO Cells; Colonic Neoplasms; Cricetinae; Ethylmaleimide; Eukaryotic Cells; Evaluation Studies as Topic; Flow Cytometry; Fluoresceins; Fluorescent Dyes; Glutathione; Humans; Maleates; Mammary Neoplasms, Experimental; Methionine Sulfoximine; Mice; o-Phthalaldehyde; Phenylmercury Compounds; Pyrazoles; Species Specificity; Tumor Cells, Cultured; Urinary Bladder Neoplasms | 1994 |
Effect of glutathione levels on aflatoxin B1-DNA binding in livers and kidneys of male rats and hamsters pretreated with buthionine sulfoximine and dimethylmaleate.
Topics: Aflatoxin B1; Animals; Antimetabolites, Antineoplastic; Biotransformation; Buthionine Sulfoximine; Cricetinae; DNA; DNA Adducts; Glutathione; Glutathione Transferase; Kidney; Liver; Male; Maleates; Mesocricetus; Methionine Sulfoximine; Rats; Rats, Inbred F344; Time Factors | 1994 |
Modifications of cellular thiols during growth and squamous differentiation of cultured human bronchial epithelial cells.
Topics: Antimetabolites; Bronchi; Buthionine Sulfoximine; Calcium; Cell Differentiation; Cell Division; Cells, Cultured; Cysteine; Cystine; Epithelial Cells; Epithelium; Glutathione; Humans; Maleates; Methionine Sulfoximine; Oxidation-Reduction; Serum Albumin, Bovine; Sulfhydryl Compounds; Transforming Growth Factor beta | 1994 |
Reactive naphthalene metabolite binding to hemoglobin and albumin.
Topics: Animals; Buthionine Sulfoximine; Electrophoresis, Polyacrylamide Gel; Glutathione; Hemoglobins; Male; Maleates; Methionine Sulfoximine; Mice; Naphthalenes; Protein Binding; Serum Albumin; Sulfhydryl Compounds | 1994 |
Effect of glutathione depletion on formation of paramagnetic chromium in Chinese hamster V-79 cells.
Topics: Animals; Buthionine Sulfoximine; Cells, Cultured; Chromates; Chromium; Cricetinae; Cricetulus; Electron Spin Resonance Spectroscopy; Glutathione; Glutathione Reductase; Maleates; Methionine Sulfoximine; Sodium Compounds | 1994 |
Free radical scavenger depletion in post-ischemic reperfusion brain damage.
Topics: Animals; Brain; Buthionine Sulfoximine; Ditiocarb; Free Radical Scavengers; Free Radicals; Glutathione; Ischemic Attack, Transient; Kinetics; Male; Maleates; Methionine Sulfoximine; Rats; Rats, Wistar; Reperfusion Injury; Superoxide Dismutase | 1993 |
Enhanced rate of H2O2 release from bovine pulmonary artery endothelial cells induced by TGF-beta 1.
Topics: Analysis of Variance; Animals; Buthionine Sulfoximine; Cattle; Cells, Cultured; Dose-Response Relationship, Drug; Endothelium, Vascular; Glutathione; Hydrogen Peroxide; Kinetics; Maleates; Methionine Sulfoximine; Pulmonary Artery; Time Factors; Transforming Growth Factor beta | 1993 |
Glutathione depletion induces heme oxygenase-1 (HSP32) mRNA and protein in rat brain.
Topics: Animals; Base Sequence; Blotting, Northern; Brain; Buthionine Sulfoximine; Glutathione; Heme Oxygenase (Decyclizing); Male; Maleates; Methionine Sulfoximine; Molecular Sequence Data; Polymerase Chain Reaction; Rats; RNA, Messenger | 1993 |
Variable glutathione levels and expression of antioxidant enzymes in human endothelial cells.
Topics: Blotting, Northern; Buthionine Sulfoximine; Catalase; Cells, Cultured; Endothelium, Vascular; Enzyme Activation; Glutathione; Glutathione Disulfide; Glutathione Peroxidase; Humans; Hypoxanthine; Hypoxanthines; L-Lactate Dehydrogenase; Maleates; Methionine Sulfoximine; Oxygen; RNA, Messenger; Superoxide Dismutase; Umbilical Veins; Xanthine Oxidase | 1993 |
Effect of nonprotein thiols on protein synthesis in isolated rat hepatocytes.
Topics: Amino Acids; Aminooxyacetic Acid; Animals; Antimetabolites; Buthionine Sulfoximine; Carbon Radioisotopes; Cells, Cultured; Cysteine; Kinetics; Liver; Maleates; Methionine; Methionine Sulfoximine; Protein Biosynthesis; Rats; Rats, Wistar; Sulfhydryl Compounds | 1996 |
Neuroprotective effect of insulin-like growth factor I in immortalized hypothalamic cells.
Topics: Animals; Benzoquinones; Buthionine Sulfoximine; Cell Death; Cell Line, Transformed; Ethacrynic Acid; Hypothalamus; Insulin-Like Growth Factor I; Maleates; Methionine Sulfoximine; Mice; Mice, Transgenic; Neurons; Neuroprotective Agents; Radiation-Protective Agents; Ubiquinone; Vitamin K | 1996 |
Thiol-mediated redox regulation of neutrophil apoptosis.
Topics: Antioxidants; Apoptosis; Buthionine Sulfoximine; Diamide; Enzyme Inhibitors; Flow Cytometry; Glutathione; Glutathione Transferase; Humans; Maleates; Methionine Sulfoximine; Neutrophils; Oxidation-Reduction; Protein-Tyrosine Kinases; Sulfhydryl Compounds; Sulfhydryl Reagents | 1996 |