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methionine sulfoximine and cysteine

methionine sulfoximine has been researched along with cysteine in 65 studies

Research

Studies (65)

TimeframeStudies, this research(%)All Research%
pre-199027 (41.54)18.7374
1990's37 (56.92)18.2507
2000's1 (1.54)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Atzori, L; Cotgreave, I; Grafström, RC; Liu, Y1
Aebi, S; Lauterburg, BH1
Magnusson, T; Pileblad, E1
Enger, MD; Kang, YJ1
Falvey, D; Frenkel, GD; MacVicar, C1
Boylan, LM; Spallholz, JE; Yan, L; Yee, JA1
Hill, L; Lailey, AF; Lawston, IW; Stanton, D; Upshall, DG1
Caffrey, PB; Frenkel, GD1
Hoffer, LJ; Hum, S; Robitaille, L1
Murray, DL; Rathbun, WB2
Standeven, AM; Wetterhahn, KE1
Djurhuus, R; Mansoor, MA; Svardal, AM; Ueland, PM1
Morita, S; Noda, T; Ohmori, M; Shimizu, M; Tsujimoto, Y; Yamada, A; Yamano, T1
Armario, A; Garvey, JS; Hidalgo, J1
Li, J; Murray, DL; Rathbun, WB1
Jacobs, WR; Mandel, LJ; Schnellmann, RG1
Brötell, H; Karg, E; Rorsman, H; Rosengren, E1
Cherian, MG; Gallant, KR1
Anderson, ME; Bridges, RJ; Meister, A; Underwood, M1
Nakagawa, K1
Hettiaratchi, P; Koch, CJ; Stobbe, CC1
Javor, B; Newton, GL1
Biscay, P; Guichard, M; Lespinasse, F; Malaise, EP1
Gescher, A; Harpur, ES; Lazenby, CM; Lee, SJ1
Ishikawa, M; Sasaki, K; Takayanagi, G1
Yeung, JH1
Calvin, HI; Cohen, G; Slivka, A; Spina, MB1
Anderstam, B; Harms-Ringdahl, M1
Nakagawa, Y1
Fricke, RF; Goon, DJ; Nagasawa, HT; Roberts, JC; Zera, RT1
Abe, M; Komuro, C; Nishidai, T; Ono, K; Shibamoto, Y; Shrieve, DC; Takahashi, M; Tsutsui, K1
Cordeiro, RF; Savarese, TM1
Brodie, AE; Reed, DJ1
Meister, A; Orlowski, M; Richman, PG1
Meister, A2
Meister, A; Orlowski, M1
Haldeman, S; McLennan, H1
Garaza, A; Sellinger, OZ1
Griffith, OW1
Berggren, M; Dawson, J; Moldéus, P1
Birkett, DJ; Drew, R; Miners, JO1
Mizutani, T; Nomura, H; Tajima, K; Yamamoto, K1
Mitchell, JB; Russo, A1
Alexandre, E; Boudjema, K; Chenard, MP; Cinqualbre, J; Imbs, P; Jaeck, D; Nakano, H; Wolf, P1
Baas, F; Beijnen, J; Borst, P; Dekker, H; Lankelma, J; Oude Elferink, RP; Paulusma, C; van Tellingen, O; Zaman, GJ1
Graham, A; O'Leary, VJ; Stone, D; Wood, JL1
Harada, T; Hiraishi, H; Ivey, KJ; Mutoh, H; Ota, S; Razandi, M; Sugimoto, T; Terano, A1
Feng, Y; Hatcher, EL; Kang, YJ1
Baraban, JM; Murphy, TH; Ratan, RR1
Hamazaki, S; Minamiyama, Y; Okada, S; Sotomatsu, A; Toyokuni, S1
Kesavan, PC; Singh, SP1
Atzori, L; Dypbukt, JM; Grafström, RC; Hybbinette, SS; Moldéus, P1
Lee, JH; Naito, M; Tsuruo, T1
Fujiyama, J; Hirayama, K; Yasutake, A1
Dockery, SP; Harrison, DG; Kurz, MA; Sayegh, HS; Wheatley, RM1
Aldershvile, J; Anderson, ME; Boesgaard, S; Loft, S; Meister, A; Poulsen, HE1
Asensi, M; Estrela, JM; Garcia-España, A; Pallardó, FV; Vina, J1
Chiba, T; Ishii, S; Kikuchi, K; Sato, N; Takahashi, S1
Baker, ER; Baker, H; DeAngelis, B; Frank, O; Hutner, SH; Khalil, M1
Benson, PJ; Gupta, V; Hu, X; Pinto, T; Singh, S; Xia, H; Zaren, HA1
Caffrey, R; McCoy, KL; Merkel, BJ; Short, S1
Jacquemin-Sablon, A; Mousset, S; Vincent, BR1
Boehlein, SK; Hiratake, J; Nakatsu, T; Richards, NG; Schuster, SM; Stewart, JD; Thirumoorthy, R1

Reviews

2 review(s) available for methionine sulfoximine and cysteine

ArticleYear
An enzymatic basis for a blood-brain barrier? The gamma-glutamyl cycle-background and considerations relating to amino acid transport in the brain.
    Research publications - Association for Research in Nervous and Mental Disease, 1974, Volume: 53

    Topics: Acyltransferases; Adult; Amidohydrolases; Amino Acids; Animals; Blood-Brain Barrier; Brain; Choroid Plexus; Cysteine; gamma-Glutamyltransferase; Glutamates; Glutamine; Glutathione; Humans; Male; Methionine Sulfoximine; Mice; Peptide Synthases; Proline; Pyrrolidonecarboxylic Acid; Rabbits

1974
Glutathione metabolism.
    Methods in enzymology, 1995, Volume: 251

    Topics: Animals; Buthionine Sulfoximine; Cysteine; Enzymes; Glutathione; Methionine Sulfoximine; Models, Biological; Oxidation-Reduction

1995

Other Studies

63 other study(ies) available for methionine sulfoximine and cysteine

ArticleYear
The mechanism of Hg2+ toxicity in cultured human oral fibroblasts: the involvement of cellular thiols.
    Chemico-biological interactions, 1992, Nov-30, Volume: 85, Issue:1

    Topics: Buthionine Sulfoximine; Cell Division; Cell Survival; Cells, Cultured; Coloring Agents; Cysteine; Dental Amalgam; Deoxyglucose; Fibroblasts; Glutathione; Humans; Mercury; Methionine Sulfoximine; Mouth; Neutral Red; Sulfhydryl Compounds; Tetrazolium Salts; Thiazoles

1992
Divergent effects of intravenous GSH and cysteine on renal and hepatic GSH.
    The American journal of physiology, 1992, Volume: 263, Issue:2 Pt 2

    Topics: Animals; Buthionine Sulfoximine; Cysteine; Dose-Response Relationship, Drug; Glutathione; Injections, Intravenous; Kidney; Kinetics; Liver; Male; Methionine Sulfoximine; Rats; Rats, Inbred Strains

1992
Increase in rat brain glutathione following intracerebroventricular administration of gamma-glutamylcysteine.
    Biochemical pharmacology, 1992, Sep-01, Volume: 44, Issue:5

    Topics: Animals; Brain; Brain Stem; Buthionine Sulfoximine; Corpus Striatum; Cysteine; Dipeptides; Glutathione; Injections, Intraventricular; Methionine Sulfoximine; Rats; Rats, Inbred Strains; Substantia Nigra

1992
Increased glutathione levels in quiescent, serum-stimulated NRK-49F cells are associated not with a response to growth factors but with nutrient repletion.
    Journal of cellular physiology, 1991, Volume: 148, Issue:2

    Topics: Animals; Blood; Buthionine Sulfoximine; Cell Division; Cell Line; Culture Media; Cysteine; DNA; Epidermal Growth Factor; Glutamates; Glutamic Acid; Glutathione; Growth Substances; Interphase; Methionine Sulfoximine

1991
Products of the reaction of selenite with intracellular sulfhydryl compounds.
    Biological trace element research, 1991, Volume: 30, Issue:1

    Topics: Antimetabolites; Autoradiography; Buthionine Sulfoximine; Chromatography, Ion Exchange; Chromatography, Thin Layer; Cysteine; Glutathione; HeLa Cells; Humans; Methionine Sulfoximine; Organoselenium Compounds; Selenious Acid; Selenium; Selenium Compounds; Selenium Radioisotopes; Selenocysteine; Sulfhydryl Compounds; Sulfides

1991
Effect of selenium compounds and thiols on human mammary tumor cells.
    Biological trace element research, 1991, Volume: 30, Issue:2

    Topics: Aged; Antimetabolites; Breast Neoplasms; Buthionine Sulfoximine; Cell Survival; Cysteine; Female; Glutathione; Glutathione Peroxidase; Humans; Mercaptoethanol; Methionine Sulfoximine; Organoselenium Compounds; Selenic Acid; Selenious Acid; Selenium; Selenium Compounds; Selenocysteine; Selenomethionine; Sodium Selenite; Sulfhydryl Compounds; Trypan Blue; Tumor Cells, Cultured

1991
Protection by cysteine esters against chemically induced pulmonary oedema.
    Biochemical pharmacology, 1991, Dec-11, Volume: 42 Suppl

    Topics: Acetylcysteine; Animals; Buthionine Sulfoximine; Chromatography, High Pressure Liquid; Cysteine; Cystine; DNA; Female; Fluorocarbons; Glutathione; Liver; Lung; Methionine Sulfoximine; Perfusion; Pulmonary Edema; Rats; Sulfhydryl Compounds; Time Factors

1991
Inhibition of cell colony formation by selenite: involvement of glutathione.
    Molecular pharmacology, 1991, Volume: 39, Issue:3

    Topics: Buthionine Sulfoximine; Cell Division; Cell Survival; Cysteine; Dose-Response Relationship, Drug; Glutathione; HeLa Cells; Humans; In Vitro Techniques; Methionine Sulfoximine; Selenious Acid; Selenium; Selenocysteine; Sulfhydryl Compounds

1991
Plasma glutathione turnover in the rat: effect of fasting and buthionine sulfoximine.
    Canadian journal of physiology and pharmacology, 1991, Volume: 69, Issue:5

    Topics: Animals; Antimetabolites; Buthionine Sulfoximine; Chromatography, High Pressure Liquid; Cysteine; Erythrocytes; Fasting; Glutathione; Hemolysis; In Vitro Techniques; Indicators and Reagents; Liver; Male; Methionine Sulfoximine; Rats; Rats, Inbred Strains; Spectrometry, Fluorescence; Sulfur Radioisotopes

1991
Age-related cysteine uptake as rate-limiting in glutathione synthesis and glutathione half-life in the cultured human lens.
    Experimental eye research, 1991, Volume: 53, Issue:2

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Buthionine Sulfoximine; Child; Child, Preschool; Chromatography, High Pressure Liquid; Cysteine; Glutathione; Half-Life; Humans; Infant; Infant, Newborn; Lens, Crystalline; Methionine Sulfoximine; Middle Aged

1991
Conditions for maximizing and inhibiting synthesis of glutathione in cultured rat lenses: an application of HPLC with radioisotope detection.
    Current eye research, 1990, Volume: 9, Issue:1

    Topics: Animals; Buthionine Sulfoximine; Chromatography, High Pressure Liquid; Culture Techniques; Cysteine; Glutamate-Cysteine Ligase; Glutathione; Lens, Crystalline; Male; Methionine Sulfoximine; Methods; Rats; Rats, Inbred Strains; Sulfhydryl Compounds; Sulfur Radioisotopes

1990
Tissue-specific changes in glutathione and cysteine after buthionine sulfoximine treatment of rats and the potential for artifacts in thiol levels resulting from tissue preparation.
    Toxicology and applied pharmacology, 1991, Volume: 107, Issue:2

    Topics: Animals; Antimetabolites; Buthionine Sulfoximine; Chromatography, High Pressure Liquid; Cysteine; Dose-Response Relationship, Drug; Glutathione; Injections, Intraperitoneal; Kidney; Liver; Male; Methionine Sulfoximine; Rats; Rats, Inbred Strains; Spectrophotometry; Sulfhydryl Compounds; Time Factors

1991
Modulation of glutathione content and the effect on methionine auxotrophy and cellular distribution of homocysteine and cysteine in mouse cell lines.
    Carcinogenesis, 1991, Volume: 12, Issue:2

    Topics: Animals; Antimetabolites; Buthionine Sulfoximine; Cell Division; Cell Line; Culture Media; Cystamine; Cysteamine; Cysteine; Fibroblasts; Glutathione; Homocysteine; Intracellular Fluid; Leukemia, Experimental; Methionine; Methionine Sulfoximine; Mice

1991
Hepatotoxicity of geniposide in rats.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 1990, Volume: 28, Issue:7

    Topics: Administration, Oral; Alanine Transaminase; Animals; Aspartate Aminotransferases; Bilirubin; Buthionine Sulfoximine; Chloramphenicol; Cysteine; Injections, Intraperitoneal; Iridoid Glycosides; Iridoids; Liver; Male; Methionine Sulfoximine; Molecular Structure; Pyrans; Rats; Rats, Inbred Strains; Sulfhydryl Compounds

1990
On the metallothionein, glutathione and cysteine relationship in rat liver.
    The Journal of pharmacology and experimental therapeutics, 1990, Volume: 255, Issue:2

    Topics: Animals; Body Weight; Buthionine Sulfoximine; Cysteine; Glutathione; Isoxazoles; Liver; Male; Metallothionein; Methionine Sulfoximine; Organ Size; Rats; Rats, Inbred Strains; Starvation; Stress, Physiological; Zinc

1990
Cysteine and glutathione metabolism in organ-cultured rat corneas.
    Current eye research, 1990, Volume: 9, Issue:9

    Topics: Animals; Buthionine Sulfoximine; Chromatography, High Pressure Liquid; Cornea; Cysteine; Glutathione; Half-Life; Male; Mercaptoethanol; Methionine Sulfoximine; Organ Culture Techniques; Oxygen Consumption; Rats; Rats, Inbred Strains

1990
Intracellular glutathione in the protection from anoxic injury in renal proximal tubules.
    The Journal of clinical investigation, 1990, Volume: 85, Issue:2

    Topics: Adenosine Triphosphate; Animals; Buthionine Sulfoximine; Cysteine; Female; Glutathione; Glycine; In Vitro Techniques; Kidney Tubules, Proximal; L-Lactate Dehydrogenase; Methionine Sulfoximine; Oxygen; Oxygen Consumption; Potassium; Rabbits

1990
Modulation of glutathione level in cultured human melanoma cells.
    Acta dermato-venereologica, 1989, Volume: 69, Issue:2

    Topics: Antimetabolites; Buthionine Sulfoximine; Cell Line; Cell Survival; Cysteine; Glutathione; Humans; Melanoma; Methionine Sulfoximine; Tumor Cells, Cultured; Vitamin K

1989
Metabolic changes in glutathione and metallothionein in newborn rat liver.
    The Journal of pharmacology and experimental therapeutics, 1989, Volume: 249, Issue:2

    Topics: Alkynes; Animals; Animals, Newborn; Buthionine Sulfoximine; Cysteine; Female; gamma-Glutamyltransferase; Glutathione; Glycine; Liver; Metallothionein; Methionine Sulfoximine; Pargyline; Pregnancy; Rats; Zinc

1989
Glutathione metabolism at the blood-cerebrospinal fluid barrier.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 1989, Volume: 3, Issue:13

    Topics: Animals; Antimetabolites; Biological Transport; Blood-Brain Barrier; Buthionine Sulfoximine; Choroid Plexus; Cysteine; Dipeptides; gamma-Glutamyltransferase; Glutathione; Isoxazoles; Male; Methionine Sulfoximine; Pyrrolidonecarboxylic Acid; Rats; Rats, Inbred Strains; Thiazoles; Thiazolidines

1989
Hepatic glutathione metabolism in mice acutely treated with lead acetate.
    Japanese journal of pharmacology, 1989, Volume: 51, Issue:2

    Topics: Amino Acids, Sulfur; Animals; Antimetabolites; Buthionine Sulfoximine; Cysteine; Glutamate-Cysteine Ligase; Glutathione; Half-Life; Injections, Intraperitoneal; Liver; Male; Methionine; Methionine Sulfoximine; Mice; Organometallic Compounds

1989
Combined radiation-protective and radiation-sensitizing agents. IV: Measurement of intracellular protector concentrations.
    International journal of radiation oncology, biology, physics, 1989, Volume: 16, Issue:4

    Topics: Animals; Ascorbic Acid; Buthionine Sulfoximine; Cell Line; Coenzyme A; Cysteine; Glutathione; Methionine Sulfoximine; Misonidazole; Radiation-Protective Agents; Radiation-Sensitizing Agents

1989
gamma-Glutamylcysteine and thiosulfate are the major low-molecular-weight thiols in halobacteria.
    Journal of bacteriology, 1985, Volume: 161, Issue:1

    Topics: Buthionine Sulfoximine; Chromatography, High Pressure Liquid; Cysteine; Dipeptides; Glutamate-Cysteine Ligase; Glutathione; Halobacterium; Methionine Sulfoximine; Thiosulfates

1985
SR-2508 plus buthionine sulfoximine or SR-2508 alone: effects on the radiation response and the glutathione content of a human tumor xenograft.
    Radiation research, 1987, Volume: 110, Issue:1

    Topics: Buthionine Sulfoximine; Cell Survival; Cysteine; Etanidazole; Glutathione; Humans; Methionine Sulfoximine; Neoplasm Transplantation; Neoplasms, Experimental; Nitroimidazoles; Radiation-Sensitizing Agents

1987
Glutathione depletion in the guinea pig and its effect on the acute cochlear toxicity of ethacrynic acid.
    Biochemical pharmacology, 1988, Oct-01, Volume: 37, Issue:19

    Topics: Animals; Buthionine Sulfoximine; Cochlea; Cysteine; Ethacrynic Acid; Female; Glutathione; Guinea Pigs; Kidney; Liver; Male; Methionine Sulfoximine; Species Specificity

1988
Effect of buthionine sulfoximine, an inhibitor of glutathione biosynthesis, on the selenium-induced lethality in mice.
    Japanese journal of pharmacology, 1988, Volume: 48, Issue:2

    Topics: Animals; Buthionine Sulfoximine; Cysteine; Drug Interactions; Glutathione; Liver; Male; Methionine Sulfoximine; Mice; Selenium

1988
Effect of sulphydryl drugs on paracetamol-induced hepatotoxicity in mice.
    Drug metabolism and drug interactions, 1988, Volume: 6, Issue:3-4

    Topics: Acetaminophen; Acetylcysteine; Alanine Transaminase; Animals; Antimetabolites; Blood Proteins; Buthionine Sulfoximine; Chemical and Drug Induced Liver Injury; Cysteine; Glutathione; Liver; Male; Methionine Sulfoximine; Mice; Mice, Inbred ICR; Sulfhydryl Compounds

1988
Depletion of brain glutathione in preweanling mice by L-buthionine sulfoximine.
    Journal of neurochemistry, 1988, Volume: 50, Issue:5

    Topics: Aging; Animals; Antimetabolites; Brain; Buthionine Sulfoximine; Cerebellum; Chromatography, High Pressure Liquid; Cysteine; Glutathione; Liver; Male; Methionine Sulfoximine; Mice; Spinal Cord; Weaning

1988
Relationship between cellular glutathione and hyperthermic toxicity in mammary carcinoma in mice.
    International journal of radiation biology and related studies in physics, chemistry, and medicine, 1986, Volume: 50, Issue:2

    Topics: Animals; Buthionine Sulfoximine; Chromatography, High Pressure Liquid; Cysteine; Female; Glutathione; Hyperthermia, Induced; Male; Mammary Neoplasms, Experimental; Methionine Sulfoximine; Mice; Mice, Inbred CBA; Neoplasm Transplantation; Sulfhydryl Compounds

1986
Effects of buthionine sulfoximine and cysteine on the hepatotoxicity of butylated hydroxytoluene in rats.
    Toxicology letters, 1987, Volume: 37, Issue:3

    Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Buthionine Sulfoximine; Butylated Hydroxytoluene; Chemical and Drug Induced Liver Injury; Cysteine; Drug Interactions; Glutathione; Lethal Dose 50; Liver Diseases; Male; Methionine Sulfoximine; Rats; Rats, Inbred F344

1987
Prodrugs of L-cysteine as protective agents against acetaminophen-induced hepatotoxicity. 2-(Polyhydroxyalkyl)- and 2-(polyacetoxyalkyl)thiazolidine-4(R)-carboxylic acids.
    Journal of medicinal chemistry, 1987, Volume: 30, Issue:10

    Topics: Acetaminophen; Animals; Buthionine Sulfoximine; Cysteine; Drug Therapy; Glutathione; Liver; Methionine Sulfoximine; Mice; Prodrugs; Rats; Structure-Activity Relationship; Thiazoles; Thiazolidines

1987
Combined effect of buthionine sulfoximine and cyclophosphamide upon murine tumours and bone marrow.
    British journal of cancer, 1986, Volume: 54, Issue:5

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Buthionine Sulfoximine; Cell Survival; Colony-Forming Units Assay; Cyclophosphamide; Cysteine; Glutathione; Lung Neoplasms; Male; Methionine Sulfoximine; Mice; Mice, Inbred C3H

1986
Role of glutathione depletion in the mechanism of action of N-methylformamide and N,N-dimethylformamide in a cultured human colon carcinoma cell line.
    Cancer research, 1986, Volume: 46, Issue:3

    Topics: Buthionine Sulfoximine; Cell Cycle; Cell Line; Cisplatin; Colonic Neoplasms; Cysteine; Dimethylformamide; Dose-Response Relationship, Drug; Formamides; Glutathione; Humans; Methionine Sulfoximine; Solvents

1986
Buthionine sulfoximine inhibition of cystine uptake and glutathione biosynthesis in human lung carcinoma cells.
    Toxicology and applied pharmacology, 1985, Mar-15, Volume: 77, Issue:3

    Topics: Buthionine Sulfoximine; Cell Line; Cysteine; Cystine; Glutathione; Humans; Lung Neoplasms; Methionine Sulfoximine; Sulfur Radioisotopes

1985
Inhibition of gamma-glutamylcysteine synthetase by L-methionine-S-sulfoximine.
    The Journal of biological chemistry, 1973, Oct-10, Volume: 248, Issue:19

    Topics: Adenosine Triphosphate; Aminobutyrates; Animals; Binding Sites; Carbon Radioisotopes; Chromatography, Gel; Cysteine; Electrophoresis, Paper; Glutamate-Ammonia Ligase; Glutamates; Kidney; Kinetics; Magnesium; Manganese; Methionine Sulfoximine; Peptide Synthases; Protein Binding; Rats; Spectrophotometry; Stereoisomerism; Structure-Activity Relationship; Sulfur Radioisotopes; Time Factors; Tritium

1973
Partial reactions catalyzed by -glutamylcysteine synthetase and evidence for an activated glutamate intermediate.
    The Journal of biological chemistry, 1971, Dec-10, Volume: 246, Issue:23

    Topics: Adenosine Diphosphate; Adenosine Triphosphatases; Adenosine Triphosphate; Animals; Carbon Isotopes; Chromatography, Gel; Chromatography, Paper; Cyclization; Cysteine; Depression, Chemical; Electrophoresis, Paper; Glutamates; Hydrogen-Ion Concentration; Hydrolysis; Kidney; Ligases; Methionine Sulfoximine; Oxidative Phosphorylation; Phosphates; Phosphorus Isotopes; Pyrrolidines; Rats; Time Factors

1971
The antagonistic action of glutamic acid diethylester towards amino acid-induced and synaptic excitations of central neurones.
    Brain research, 1972, Oct-27, Volume: 45, Issue:2

    Topics: Action Potentials; Amino Acids; Animals; Aspartic Acid; Cats; Cysteine; Electric Stimulation; Esters; Excitatory Amino Acid Antagonists; Glutamates; Homocysteine; Interneurons; Iontophoresis; Medulla Oblongata; Methionine Sulfoximine; Spinal Cord; Synaptic Transmission; Thalamic Nuclei; Thalamus

1972
The inhibition of cerebral glutamine synthetase by structural analogs of the convulsant dl-methionine sulfoximine.
    Biochemical pharmacology, 1966, Volume: 15, Issue:3

    Topics: Animals; Cerebral Cortex; Cysteine; Enzymes; Glutamine; Homocysteine; In Vitro Techniques; Ligases; Methionine; Methionine Sulfoximine; Rats

1966
Glutathione turnover in human erythrocytes. Inhibition by buthionine sulfoximine and incorporation of glycine by exchange.
    The Journal of biological chemistry, 1981, May-25, Volume: 256, Issue:10

    Topics: Buthionine Sulfoximine; Cysteine; Erythrocytes; Glutamates; Glutamic Acid; Glutathione; Glycine; Humans; Kinetics; Methionine Sulfoximine

1981
Glutathione biosynthesis in the isolated perfused rat lung: utilization of extracellular glutathione.
    FEBS letters, 1984, Oct-15, Volume: 176, Issue:1

    Topics: Acetylcysteine; Animals; Buthionine Sulfoximine; Cysteine; gamma-Glutamyltransferase; Glutamate-Cysteine Ligase; Glutamates; Glutathione; In Vitro Techniques; Lung; Male; Methionine Sulfoximine; Perfusion; Rats; Rats, Inbred Strains

1984
Mechanism of action of paracetamol protective agents in mice in vivo.
    Biochemical pharmacology, 1984, Oct-01, Volume: 33, Issue:19

    Topics: Acetaminophen; Acetylcysteine; Alanine Transaminase; Animals; Buthionine Sulfoximine; Cysteamine; Cysteine; Glutathione; Liver; Male; Methionine; Methionine Sulfoximine; Mice; Mice, Inbred C3H

1984
Modification of butylated hydroxytoluene-induced pulmonary toxicity in mice by diethyl maleate, buthionine sulfoximine, and cysteine.
    Toxicology letters, 1984, Volume: 23, Issue:3

    Topics: Animals; Body Weight; Buthionine Sulfoximine; Butylated Hydroxytoluene; Cysteine; Drug Synergism; Glutathione; Liver; Lung; Male; Maleates; Methionine Sulfoximine; Mice; Organ Size

1984
Thiols, thiol depletion, and thermosensitivity.
    Radiation research, 1983, Volume: 95, Issue:3

    Topics: Acetylcysteine; Animals; Buthionine Sulfoximine; Cell Survival; Cells, Cultured; Cricetinae; Cysteine; Glutathione; Heat-Shock Proteins; Hot Temperature; Maleates; Methionine Sulfoximine; Oxidation-Reduction; Oxygen Consumption; Protein Biosynthesis; Sulfhydryl Compounds; Time Factors

1983
Protective effects of N-acetylcysteine on hypothermic ischemia-reperfusion injury of rat liver.
    Hepatology (Baltimore, Md.), 1995, Volume: 22, Issue:2

    Topics: Acetylcysteine; Acid Phosphatase; Alanine Transaminase; Animals; Aspartate Aminotransferases; Buthionine Sulfoximine; Cold Temperature; Cysteine; Glutathione; L-Lactate Dehydrogenase; Liver; Male; Methionine Sulfoximine; Oxidation-Reduction; Rats; Rats, Wistar; Reperfusion Injury

1995
Role of glutathione in the export of compounds from cells by the multidrug-resistance-associated protein.
    Proceedings of the National Academy of Sciences of the United States of America, 1995, Aug-15, Volume: 92, Issue:17

    Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents; Arsenites; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP-Binding Cassette Transporters; Buthionine Sulfoximine; Carcinoma, Non-Small-Cell Lung; Cell Division; Cysteine; Drug Resistance, Multiple; Glutathione; Humans; Kinetics; Lung Neoplasms; Methionine Sulfoximine; Multidrug Resistance-Associated Proteins; Recombinant Proteins; Transfection; Tumor Cells, Cultured

1995
Human (THP-1) macrophages oxidize LDL by a thiol-dependent mechanism.
    Free radical research, 1994, Volume: 21, Issue:5

    Topics: Buthionine Sulfoximine; Copper; Cysteine; Cystine; Glutathione; Humans; Lipoproteins, LDL; Macrophages; Methionine Sulfoximine; Oxidation-Reduction; Tumor Cells, Cultured

1994
Protection of cultured rat gastric cells against oxidant-induced damage by exogenous glutathione.
    Gastroenterology, 1994, Volume: 106, Issue:5

    Topics: Animals; Buthionine Sulfoximine; Cells, Cultured; Chromium Radioisotopes; Cysteine; Dose-Response Relationship, Drug; Female; gamma-Glutamyltransferase; Glucose; Glucose Oxidase; Glutamate-Cysteine Ligase; Glutathione; Hydrogen Peroxide; Isoxazoles; Male; Methionine Sulfoximine; Protein Precursors; Rats; Rats, Sprague-Dawley; Resting Phase, Cell Cycle; Stomach

1994
Glutathione stimulates A549 cell proliferation in glutamine-deficient culture: the effect of glutamate supplementation.
    Journal of cellular physiology, 1994, Volume: 161, Issue:3

    Topics: Buthionine Sulfoximine; Cell Division; Cysteine; gamma-Glutamyltransferase; Glutamates; Glutamine; Glutathione; Humans; In Vitro Techniques; Methionine Sulfoximine; Tumor Cells, Cultured

1994
Macromolecular synthesis inhibitors prevent oxidative stress-induced apoptosis in embryonic cortical neurons by shunting cysteine from protein synthesis to glutathione.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1994, Volume: 14, Issue:7

    Topics: Acetylcysteine; Animals; Apoptosis; Buthionine Sulfoximine; Cells, Cultured; Cerebral Cortex; Cycloheximide; Cysteine; Glutamates; Glutathione; Homocysteine; Macromolecular Substances; Methionine Sulfoximine; Neurons; Oxidants; Protein Biosynthesis; Proteins; Rats

1994
Glutathione cycle dependency of ferric nitrilotriacetate-induced lipid peroxidation in mouse proximal renal tubules.
    Archives of biochemistry and biophysics, 1993, Feb-15, Volume: 301, Issue:1

    Topics: Aging; Animals; Buthionine Sulfoximine; Cysteine; Fatty Acids; Fatty Acids, Unsaturated; Female; Ferric Compounds; gamma-Glutamyltransferase; Glutathione; Glutathione Synthase; Kidney Cortex; Kidney Medulla; Kidney Tubules, Proximal; Lipid Peroxidation; Male; Methionine Sulfoximine; Mice; Nitrilotriacetic Acid; Sex Characteristics; Thiobarbiturates

1993
Post-irradiation modification of O2, N2, and N2O-mediated damage in dry barley seeds by glutathione and cysteine: probable radiation chemical events.
    International journal of radiation biology, 1993, Volume: 63, Issue:4

    Topics: Buthionine Sulfoximine; Cobalt Radioisotopes; Cysteine; Gamma Rays; Glutathione; Hordeum; Methionine Sulfoximine; Nitrogen; Nitrous Oxide; Oxygen; Radiation-Protective Agents; Seeds; Water

1993
Modifications of cellular thiols during growth and squamous differentiation of cultured human bronchial epithelial cells.
    Experimental cell research, 1994, Volume: 211, Issue:1

    Topics: Antimetabolites; Bronchi; Buthionine Sulfoximine; Calcium; Cell Differentiation; Cell Division; Cells, Cultured; Cysteine; Cystine; Epithelial Cells; Epithelium; Glutathione; Humans; Maleates; Methionine Sulfoximine; Oxidation-Reduction; Serum Albumin, Bovine; Sulfhydryl Compounds; Transforming Growth Factor beta

1994
Nonenzymatic reductive activation of 7-N-((2-([2-(gamma-L-glutamylamino)ethyl]dithio)ethyl))mitomycin C by thiol molecules: a novel mitomycin C derivative effective on mitomycin C-resistant tumor cells.
    Cancer research, 1994, May-01, Volume: 54, Issue:9

    Topics: Buthionine Sulfoximine; Colonic Neoplasms; Cysteine; Cytochrome P-450 Enzyme System; DNA, Neoplasm; Drug Interactions; Drug Resistance; Glutathione; Humans; Methionine Sulfoximine; Mitomycin; Mitomycins; Oxidation-Reduction; Sulfhydryl Compounds; Tumor Cells, Cultured; Tumor Stem Cell Assay

1994
Mechanism of methylmercury efflux from cultured astrocytes.
    Biochemical pharmacology, 1994, Apr-29, Volume: 47, Issue:9

    Topics: Animals; Astrocytes; Buthionine Sulfoximine; Cells, Cultured; Cysteine; Glutathione; Methionine Sulfoximine; Methylmercury Compounds; Probenecid; Pyrrolidonecarboxylic Acid; Rats; Thiazoles; Thiazolidines

1994
Interactions of nitroglycerin and sulfhydryl-donating compounds in coronary microvessels.
    The American journal of physiology, 1994, Volume: 266, Issue:1 Pt 2

    Topics: Animals; Blood Vessels; Buffers; Buthionine Sulfoximine; Coronary Circulation; Cysteine; Dogs; Drug Interactions; Female; Glutathione; Male; Methionine Sulfoximine; Microcirculation; Nitric Oxide; Nitroglycerin; Oxygen; Sulfhydryl Compounds; Vasodilation

1994
Acute effects of nitroglycerin depend on both plasma and intracellular sulfhydryl compound levels in vivo. Effect of agents with different sulfhydryl-modulating properties.
    Circulation, 1993, Volume: 87, Issue:2

    Topics: Animals; Aorta; Buthionine Sulfoximine; Cysteine; Female; Glutathione; Intracellular Membranes; Methionine Sulfoximine; Nitroglycerin; Rats; Rats, Wistar; Sulfhydryl Compounds; Time Factors; Vena Cava, Superior

1993
Effect of nonprotein thiols on protein synthesis in isolated rat hepatocytes.
    Experientia, 1996, Feb-15, Volume: 52, Issue:2

    Topics: Amino Acids; Aminooxyacetic Acid; Animals; Antimetabolites; Buthionine Sulfoximine; Carbon Radioisotopes; Cells, Cultured; Cysteine; Kinetics; Liver; Maleates; Methionine; Methionine Sulfoximine; Protein Biosynthesis; Rats; Rats, Wistar; Sulfhydryl Compounds

1996
Fas-mediated apoptosis is modulated by intracellular glutathione in human T cells.
    European journal of immunology, 1996, Volume: 26, Issue:5

    Topics: Acetylcysteine; Apoptosis; Buthionine Sulfoximine; Culture Media, Conditioned; Cycloheximide; Cysteine; Cytotoxicity, Immunologic; fas Receptor; Glutathione; Humans; Immunity, Innate; Intracellular Fluid; Killer Cells, Lymphokine-Activated; Leukemia, T-Cell; Lymphocyte Activation; Methionine Sulfoximine; T-Lymphocytes; Tumor Cells, Cultured

1996
Antioxidant survey to assess antagonism to redox stress using a prokaryotic and an eukaryotic system.
    Experientia, 1996, Jun-15, Volume: 52, Issue:6

    Topics: Antioxidants; Buthionine Sulfoximine; Cysteine; Escherichia coli; Eukaryota; Free Radicals; Glutathione; Homocysteine; Methionine Sulfoximine; Oxidative Stress; Pyrrolidonecarboxylic Acid; Thiazoles; Thiazolidines; Vitamin K; Vitamin K 3

1996
Lack of a role of glutathione in cellular nonenzymatic activation of BMS-181174, a novel analogue of mitomycin C.
    Cancer research, 1996, Aug-01, Volume: 56, Issue:15

    Topics: Antineoplastic Agents, Alkylating; Biotransformation; Buthionine Sulfoximine; Cysteine; Enzyme Inhibitors; Glutamate-Cysteine Ligase; Glutathione; Humans; Methionine Sulfoximine; Mitomycin; Mitomycins; Tumor Cells, Cultured; Urinary Bladder Neoplasms

1996
Defective antigen processing correlates with a low level of intracellular glutathione.
    European journal of immunology, 1996, Volume: 26, Issue:12

    Topics: Acetylcysteine; Animals; Antigen Presentation; Biological Transport; CHO Cells; Cricetinae; Cysteine; Cytochrome c Group; Glutathione; Hybrid Cells; Intracellular Fluid; L Cells; Methionine Sulfoximine; Mice; Muramidase

1996
Cysteine control over glutathione homeostasis in Chinese hamster fibroblasts overexpressing a gamma-glutamylcysteine synthetase activity.
    European journal of biochemistry, 1999, Volume: 262, Issue:3

    Topics: Animals; Antineoplastic Agents; Cells, Cultured; Clone Cells; Cricetinae; Cricetulus; Cysteine; Drug Resistance; Enzyme Precursors; Fibroblasts; Glutamate-Cysteine Ligase; Glutathione; Homeostasis; Kinetics; Lung; Methionine Sulfoximine; Mutation

1999
Characterization of inhibitors acting at the synthetase site of Escherichia coli asparagine synthetase B.
    Biochemistry, 2001, Sep-18, Volume: 40, Issue:37

    Topics: Adenosine Monophosphate; Adenosine Triphosphate; Asparagine; Carbon-Nitrogen Ligases with Glutamine as Amide-N-Donor; Cysteine; Enzyme Inhibitors; Escherichia coli; Hydrolysis; Methionine Sulfoximine; Models, Chemical; Neurotransmitter Agents; Nuclear Magnetic Resonance, Biomolecular; Phosphorus Isotopes; Spectrometry, Mass, Electrospray Ionization

2001