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methionine sulfoximine and carmustine

methionine sulfoximine has been researched along with carmustine in 34 studies

Research

Studies (34)

TimeframeStudies, this research(%)All Research%
pre-199010 (29.41)18.7374
1990's23 (67.65)18.2507
2000's1 (2.94)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Guenthner, TM; Jevtović-Todorović, V1
Allalunis-Turner, MJ; Barron, GM; Day, RS; Dobler, K; Urtasun, RC1
Canada, AT; Romero, MJ1
Brunmark, A; Ollinger, K1
Allalunis-Turner, MJ; Allen, PB; Aronyk, KE; Day, RS; Fulton, DS; Huyser-Wierenga, D; McKean, JD; Petruk, KC; Urtasun, RC; Weir, BK1
Hiraishi, H; Ivey, KJ; Mutoh, H; Ota, S; Razandi, M; Sugimoto, T; Terano, A1
Costarides, AP; Green, K; Riley, MV2
Mehendale, HM; Utley, WS1
Benz, CC; Ford, JM; Hait, WN; Matlin, SA1
Brand, S; Forrester, T; Golden, M; Swales, J1
Beaujean, F; Goavec, M; Ito, H; Morizet, J; Rousseau, V; Stanislawski, M1
Costarides, A; Green, K; Recasens, JF; Riley, MV1
DeHart, PD; Nadeau, DM; Simon, RH1
Abarzua, M; Davis, JA; Kiani, T; Weinberg, JM1
Goavec, M; Ito, H; Rousseau, V; Stanislawski, M1
Bodell, WJ; Doane-Setzer, P; Evans, CG; Smith, MT; Tokuda, K1
Michiels, C; Remacle, J1
Deen, DF; Hunter, KJ; Marton, LJ1
Cieslinski, DA; Humes, HD; Messana, JM; O'Connor, RP1
Adams, GE1
Callahan, KS; Harker, LA; Harlan, JM; Levine, JD; Schwartz, BR1
Gardiner, CS; Reed, DJ1
Graham, A; Wood, JL1
Buttin, G; De Saint Vincent, BR; Lunel-Orsini, C1
Awad, JA; Burk, RF; Roberts, LJ1
Hempel, SL; Wessels, DA1
Chigurupati, R; Frischer, H; Kennedy, EJ; Sivarajan, M1
Eisert, DR; Freeman, ML; Meredith, MJ; Sierra-Rivera, E; Voorhees, GJ1
Harris, C; Hiranruengchok, R1
Elliott, SJ; Henschke, PN1
Averill-Bates, DA; Przybytkowski, E1
Ali-Osman, F; Antoun, G; Gagucas, E; Rajagopal, S; Wang, H1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1

Other Studies

34 other study(ies) available for methionine sulfoximine and carmustine

ArticleYear
Depletion of a discrete nuclear glutathione pool by oxidative stress, but not by buthionine sulfoximine. Correlation with enhanced alkylating agent cytotoxicity to human melanoma cells in vitro.
    Biochemical pharmacology, 1992, Oct-06, Volume: 44, Issue:7

    Topics: Buthionine Sulfoximine; Carmustine; Cell Division; Cell Nucleus; Cytosol; Doxorubicin; Drug Synergism; Glutathione; Glutathione Disulfide; Humans; Melanoma; Melphalan; Methionine Sulfoximine; Oxidation-Reduction; Tumor Cells, Cultured

1992
Heterogeneity in response to treatment with buthionine sulfoximine or interferon in human malignant glioma cells.
    International journal of radiation oncology, biology, physics, 1992, Volume: 22, Issue:4

    Topics: Buthionine Sulfoximine; Carmustine; Humans; In Vitro Techniques; Interferon-alpha; Mechlorethamine; Methionine Sulfoximine; Recombinant Proteins; Tumor Cells, Cultured

1992
The evaluation of Escherichia coli as a model for oxidant stress in mammalian hepatocytes: role of glutathione.
    Toxicology and applied pharmacology, 1991, Volume: 111, Issue:3

    Topics: Animals; Buthionine Sulfoximine; Carmustine; Escherichia coli; Glutathione; Glutathione Reductase; Hydrogen Peroxide; Liver; Methionine Sulfoximine; Models, Biological; Oxidation-Reduction; Paraquat; Peroxides; Superoxides; tert-Butylhydroperoxide

1991
Effect of hydroxy substituent position on 1,4-naphthoquinone toxicity to rat hepatocytes.
    The Journal of biological chemistry, 1991, Nov-15, Volume: 266, Issue:32

    Topics: Animals; Buthionine Sulfoximine; Carmustine; Cell Survival; Dicumarol; Glutathione; Liver; Male; Methionine Sulfoximine; Mitochondria, Liver; Molecular Structure; Naphthoquinones; Oxidation-Reduction; Oxygen Consumption; Rats; Rats, Inbred Strains; Structure-Activity Relationship

1991
Glutathione levels and chemosensitizing effects of buthionine sulfoximine in human malignant glioma cells.
    Journal of neuro-oncology, 1991, Volume: 11, Issue:2

    Topics: Adolescent; Adult; Aged; Antimetabolites, Antineoplastic; Brain Neoplasms; Buthionine Sulfoximine; Carmustine; Child; Drug Screening Assays, Antitumor; Drug Synergism; Female; Glioma; Glutathione; Humans; Male; Mechlorethamine; Methionine Sulfoximine; Middle Aged; Tumor Cells, Cultured

1991
Antioxidant defenses of cultured gastric cells against oxygen metabolites: role of GSH redox cycle and endogenous catalase.
    The American journal of physiology, 1991, Volume: 261, Issue:6 Pt 1

    Topics: Animals; Antimetabolites; Buthionine Sulfoximine; Carmustine; Catalase; Cells, Cultured; Chromium; Female; Gastric Mucosa; Glucose; Glucose Oxidase; Glutathione; Glutathione Reductase; Hydrogen Peroxide; Lipid Peroxidation; Male; Maleates; Methionine Sulfoximine; Oxidation-Reduction; Oxygen; Rats; Rats, Inbred Strains

1991
Roles of catalase and the glutathione redox cycle in the regulation of anterior-chamber hydrogen peroxide.
    Ophthalmic research, 1991, Volume: 23, Issue:5

    Topics: Amitrole; Animals; Anterior Chamber; Anterior Eye Segment; Antimetabolites; Aqueous Humor; Ascorbic Acid; Buthionine Sulfoximine; Carmustine; Catalase; Glutathione; Glutathione Reductase; Hydrogen Peroxide; Methionine Sulfoximine; Oxidation-Reduction; Rabbits

1991
Evidence for stimulated glutathione synthesis by phenobarbital pretreatment during an oxidative challenge in isolated hepatocytes.
    Journal of biochemical toxicology, 1991,Summer, Volume: 6, Issue:2

    Topics: Animals; Buthionine Sulfoximine; Carmustine; Glutathione; Glutathione Reductase; Homeostasis; In Vitro Techniques; L-Lactate Dehydrogenase; Liver; Male; Methionine Sulfoximine; Oxidation-Reduction; Phenobarbital; Rats; Rats, Inbred Strains; Trypan Blue; Vitamin K

1991
Modulation of resistance to alkylating agents in cancer cell by gossypol enantiomers.
    Cancer letters, 1991, Volume: 56, Issue:1

    Topics: Alkylating Agents; Animals; Breast Neoplasms; Buthionine Sulfoximine; Carcinoma 256, Walker; Carmustine; Cell Division; Cell Line; Chlorambucil; Cisplatin; Drug Antagonism; Drug Resistance; Glutathione Transferase; Gossypol; Humans; In Vitro Techniques; Isomerism; Melphalan; Methionine Sulfoximine; Rats

1991
Role of glutathione in the regulation of anterior chamber hydrogen peroxide.
    Lens and eye toxicity research, 1990, Volume: 7, Issue:3-4

    Topics: Amitrole; Animals; Anterior Chamber; Antimetabolites; Buthionine Sulfoximine; Carmustine; Catalase; Ciliary Body; Glutathione; Glutathione Reductase; Hydrogen Peroxide; Iris; Methionine Sulfoximine; Oxidation-Reduction; Rabbits

1990
Reduction in vitro of red cell glutathione reproduces defects of cellular sodium transport seen in oedematous malnutrition.
    European journal of clinical nutrition, 1990, Volume: 44, Issue:5

    Topics: Adult; Antimetabolites; Buthionine Sulfoximine; Carmustine; Erythrocyte Membrane; Erythrocytes; Glutathione; Humans; In Vitro Techniques; Kwashiorkor; Male; Methionine Sulfoximine; Protein-Energy Malnutrition; Sodium; Sodium Channels

1990
Enhanced in vitro cytotoxicity of 1,3-bis-(2-chloroethyl)-1-nitrosourea or buthionine sulfoximine combined with a reactive oxygen-generating enzyme immunotoxin.
    Cancer letters, 1990, Volume: 49, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Buthionine Sulfoximine; Carmustine; Cell Survival; Cells, Cultured; Drug Synergism; Glucose Oxidase; Glutathione; Humans; Immunotoxins; Lactoperoxidase; Lymphoma; Methionine Sulfoximine; T-Lymphocytes

1990
The effects of ascorbate, 3-aminotriazole, and 1,3-bis-(2-chloroethyl)-1-nitrosourea on hydrogen peroxide levels in the rabbit aqueous humor.
    Lens and eye toxicity research, 1989, Volume: 6, Issue:1-2

    Topics: Amitrole; Animals; Aqueous Humor; Ascorbic Acid; Buthionine Sulfoximine; Carmustine; Catalase; Ciliary Body; Glutathione; Glutathione Reductase; Hydrogen Peroxide; Iris; Methionine Sulfoximine; Rabbits

1989
Resistance of rat pulmonary alveolar epithelial cells to neutrophil- and oxidant-induced injury.
    American journal of respiratory cell and molecular biology, 1989, Volume: 1, Issue:3

    Topics: Amitrole; Animals; Azides; Buthionine Sulfoximine; Carmustine; Catalase; Cells, Cultured; Epithelium; Glutathione; Glyceraldehyde-3-Phosphate Dehydrogenases; Hydrogen Peroxide; Methionine Sulfoximine; Neutrophils; Oxidation-Reduction; Pulmonary Alveoli; Rats; Rats, Inbred F344

1989
Relationship between cell adenosine triphosphate and glutathione content and protection by glycine against hypoxic proximal tubule cell injury.
    The Journal of laboratory and clinical medicine, 1989, Volume: 113, Issue:5

    Topics: Adenosine Triphosphate; Animals; Buthionine Sulfoximine; Carmustine; Glutathione; Glycine; Kidney Tubules, Proximal; L-Lactate Dehydrogenase; Methionine Sulfoximine; Oxygen; Potassium; Rabbits

1989
Immunotoxins containing glucose oxidase and lactoperoxidase with tumoricidal properties: in vitro killing effectiveness in a mouse plasmacytoma cell model.
    Cancer research, 1989, Oct-15, Volume: 49, Issue:20

    Topics: Animals; Bone Marrow; Buthionine Sulfoximine; Carmustine; Dose-Response Relationship, Immunologic; Drug Synergism; Glucose Oxidase; Glutathione; Immunization, Passive; Immunotherapy; Immunotoxins; Lactoperoxidase; Methionine Sulfoximine; Mice; Mice, Inbred BALB C; Peroxidases; Plasmacytoma

1989
Glutathione and related enzymes in rat brain tumor cell resistance to 1,3-bis(2-chloroethyl)-1-nitrosourea and nitrogen mustard.
    Cancer research, 1987, May-15, Volume: 47, Issue:10

    Topics: Animals; Brain Neoplasms; Buthionine Sulfoximine; Carmustine; Cell Line; Cell Survival; Chromatography, High Pressure Liquid; Clone Cells; Dinitrochlorobenzene; Drug Resistance; gamma-Glutamyltransferase; Glioma; Glutathione; Glutathione Transferase; Lomustine; Mechlorethamine; Methionine Sulfoximine; Rats; Semustine

1987
Use of the inhibition of enzymatic antioxidant systems in order to evaluate their physiological importance.
    European journal of biochemistry, 1988, Nov-01, Volume: 177, Issue:2

    Topics: Amitrole; Buthionine Sulfoximine; Carmustine; Catalase; Cell Survival; Ditiocarb; Fibroblasts; Glutamate-Cysteine Ligase; Glutathione; Glutathione Peroxidase; Glutathione Reductase; Humans; Methionine Sulfoximine; Superoxide Dismutase; Thiomalates

1988
Changes in the glutathione content of rat 9L cells induced by treatment with the ornithine decarboxylase inhibitor alpha-difluoromethylornithine.
    Cancer research, 1987, Oct-15, Volume: 47, Issue:20

    Topics: Alkylating Agents; Animals; Buthionine Sulfoximine; Carmustine; Eflornithine; Glutathione; Methionine Sulfoximine; Ornithine Decarboxylase Inhibitors; Putrescine; Rats; Spermidine

1987
Glutathione protects against exogenous oxidant injury to rabbit renal proximal tubules.
    The American journal of physiology, 1988, Volume: 255, Issue:5 Pt 2

    Topics: Adenosine Triphosphate; Animals; Buthionine Sulfoximine; Carmustine; Cell Membrane Permeability; Cell Survival; Glutathione; Kidney Tubules, Proximal; Kinetics; Lipid Peroxides; Malates; Malondialdehyde; Methionine Sulfoximine; Oxidation-Reduction; Oxygen Consumption; Peroxides; Potassium; Rabbits; tert-Butylhydroperoxide

1988
Radiosensitizers: a conference preview.
    International journal of radiation oncology, biology, physics, 1984, Volume: 10, Issue:8

    Topics: Animals; Aziridines; Buthionine Sulfoximine; Carmustine; Combined Modality Therapy; Drug Synergism; Etanidazole; Humans; Ketones; Lomustine; Maleates; Methionine Sulfoximine; Mice; Misonidazole; Neoplasms; Nitroimidazoles; Radiation-Sensitizing Agents

1984
Glutathione redox cycle protects cultured endothelial cells against lysis by extracellularly generated hydrogen peroxide.
    The Journal of clinical investigation, 1984, Volume: 73, Issue:3

    Topics: Animals; Blood Vessels; Buthionine Sulfoximine; Carmustine; Cattle; Cells, Cultured; Dinitrochlorobenzene; Endothelium; Glutathione; Glutathione Peroxidase; Glutathione Reductase; Humans; Hydrogen Peroxide; Maleates; Methionine Sulfoximine; Oxidation-Reduction

1984
Glutathione redox cycle-driven recovery of reduced glutathione after oxidation by tertiary-butyl hydroperoxide in preimplantation mouse embryos.
    Archives of biochemistry and biophysics, 1995, Aug-01, Volume: 321, Issue:1

    Topics: Animals; Antimetabolites; Blastocyst; Buthionine Sulfoximine; Carmustine; Dose-Response Relationship, Drug; Female; Glutathione; Glutathione Disulfide; In Vitro Techniques; Kinetics; Methionine Sulfoximine; Mice; Mice, Inbred Strains; Oxidation-Reduction; Peroxides; Reactive Oxygen Species; Superovulation; tert-Butylhydroperoxide

1995
The role of thiols in oxidation of low-density lipoprotein by macrophages.
    Biochemical Society transactions, 1995, Volume: 23, Issue:2

    Topics: Antimetabolites; Buthionine Sulfoximine; Carmustine; Cell Line; Cell-Free System; Cystine; Humans; Kinetics; Lipoproteins, LDL; Macrophages; Methionine Sulfoximine; Oxidation-Reduction; S-Adenosylmethionine; Sulfhydryl Compounds; Thiobarbituric Acid Reactive Substances; Tubercidin

1995
A glutathione depletion selectively imposed on mu glutathione S-transferase overproducing cells increases nitrogen mustard toxicity.
    Biochemical pharmacology, 1995, Jan-31, Volume: 49, Issue:3

    Topics: Animals; Buthionine Sulfoximine; Carmustine; Cell Line; Cell Survival; Cisplatin; Cricetinae; Cricetulus; Doxorubicin; Glutathione; Glutathione Transferase; Inactivation, Metabolic; Mechlorethamine; Methionine Sulfoximine

1995
Effect of selenium deficiency and glutathione-modulating agents on diquat toxicity and lipid peroxidation in rats.
    The Journal of pharmacology and experimental therapeutics, 1994, Volume: 270, Issue:3

    Topics: Animals; Antimetabolites; Arachidonic Acids; Buthionine Sulfoximine; Carmustine; Diquat; Glutathione; Ketones; Kidney; Lipid Peroxidation; Liver; Lung; Male; Methionine Sulfoximine; Rats; Rats, Inbred F344; Selenium

1994
Prostaglandin E2 synthesis after oxidant stress is dependent on cell glutathione content.
    The American journal of physiology, 1994, Volume: 266, Issue:5 Pt 1

    Topics: 3T3 Cells; Animals; Antimetabolites; Arachidonic Acid; Buthionine Sulfoximine; Carmustine; Chromatography, High Pressure Liquid; Dinitrochlorobenzene; Dinoprostone; Glutathione; Hydrogen Peroxide; Kinetics; Methionine Sulfoximine; Mice; Proteins

1994
Glutathione, cell proliferation, and 1,3-bis-(2-chloroethyl)-1-nitrosourea in K562 leukemia.
    The Journal of clinical investigation, 1993, Volume: 92, Issue:6

    Topics: Buthionine Sulfoximine; Carmustine; Cell Cycle; Cell Division; Cell Line; DNA Repair; DNA, Neoplasm; Dose-Response Relationship, Drug; Glutathione; Glutathione Reductase; Humans; Kinetics; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Methionine Sulfoximine; Tumor Cells, Cultured

1993
Synthesis of hsp-70 is enhanced in glutathione-depleted Hep G2 cells.
    Radiation research, 1993, Volume: 135, Issue:3

    Topics: Buthionine Sulfoximine; Carmustine; Cells, Cultured; Dimethyl Sulfoxide; Glutathione; Heat-Shock Proteins; Hot Temperature; Humans; Methionine Sulfoximine; Oxidation-Reduction; RNA, Messenger

1993
Glutathione oxidation and embryotoxicity elicited by diamide in the developing rat conceptus in vitro.
    Toxicology and applied pharmacology, 1993, Volume: 120, Issue:1

    Topics: Animals; Antimetabolites; Buthionine Sulfoximine; Carmustine; Chromatography, High Pressure Liquid; Diamide; Embryo, Mammalian; Female; Glutaredoxins; Glutathione; Glutathione Disulfide; In Vitro Techniques; Methionine Sulfoximine; Oxidation-Reduction; Oxidoreductases; Protein Disulfide Reductase (Glutathione); Rats; Rats, Sprague-Dawley

1993
Oxidized glutathione decreases luminal Ca2+ content of the endothelial cell ins(1,4,5)P3-sensitive Ca2+ store.
    The Biochemical journal, 1995, Dec-01, Volume: 312 ( Pt 2)

    Topics: Animals; Antimetabolites; Antioxidants; Buthionine Sulfoximine; Calcium; Carmustine; Cattle; Cells, Cultured; Cytosol; Endothelium, Vascular; Glutathione; Glutathione Disulfide; Hydroquinones; Inositol 1,4,5-Trisphosphate; Methionine Sulfoximine; Oxidants; Peroxides; Pulmonary Artery; Signal Transduction; tert-Butylhydroperoxide

1995
Correlation between glutathione and stimulation of the pentose phosphate cycle in situ in Chinese hamster ovary cells exposed to hydrogen peroxide.
    Archives of biochemistry and biophysics, 1996, Jan-01, Volume: 325, Issue:1

    Topics: Amitrole; Animals; Buthionine Sulfoximine; Carmustine; CHO Cells; Cricetinae; Enzyme Inhibitors; Glucosephosphate Dehydrogenase; Glutamate-Cysteine Ligase; Glutathione; Hydrogen Peroxide; Kinetics; Methionine Sulfoximine; Oxidation-Reduction; Paraquat; Pentose Phosphate Pathway

1996
Buthionine sulfoximine induction of gamma-L-glutamyl-L-cysteine synthetase gene expression, kinetics of glutathione depletion and resynthesis, and modulation of carmustine-induced DNA-DNA cross-linking and cytotoxicity in human glioma cells.
    Molecular pharmacology, 1996, Volume: 49, Issue:6

    Topics: Antineoplastic Agents, Alkylating; Base Sequence; Buthionine Sulfoximine; Carmustine; Cell Survival; DNA; Dose-Response Relationship, Drug; Gene Expression Regulation, Enzymologic; Glioma; Glutamate-Cysteine Ligase; Glutathione; Humans; Kinetics; Methionine Sulfoximine; Molecular Sequence Data

1996
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007