methionine sulfoximine has been researched along with azomycin in 22 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 18 (81.82) | 18.7374 |
| 1990's | 4 (18.18) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Basas, RA; Ling, CC; Wong, RS | 1 |
| Gipp, JJ; McClelland, RA; Mulcahy, RT | 1 |
| Basas, RD; Ling, CC; Wong, RS | 1 |
| Gipp, JJ; McClelland, RA; Mulcahy, RT; Ublacker, GA | 1 |
| Howes, AE; Kramer, RA; Montoya, VP; Soble, M | 1 |
| Albright, N; DeGraff, WG; Mitchell, JB; Phillips, TL; Rajpal, R; Russo, A | 1 |
| Aldunate, J; Letelier, ME; Moncada, C; Morello, A; Repetto, Y | 1 |
| Evans, WK; Stewart, DJ | 1 |
| Gipp, JJ; McClelland, RA; Mulcahy, RT; Panicucci, R; Ublacker, GA | 1 |
| Astor, MB; Biaglow, JE; Clark, EP; Epp, ER; Hall, EJ; Roizen-Towle, L; Varnes, ME | 1 |
| Dobson, PP; Fornace, AJ; Kinsella, TJ; Mitchell, JB; Russo, A | 1 |
| Biaglow, JE; Clark, EP; Donahue, LL; Epp, ER; Tuttle, SW; Varnes, ME | 1 |
| Biscay, P; Guichard, M; Lespinasse, F; Malaise, EP | 1 |
| Roizin-Towle, L | 1 |
| Edgren, M; Nishidai, T; Révész, L; Scott, OC | 1 |
| Edgren, M; Révész, L | 1 |
| Hodgkiss, RJ; Middleton, RW | 2 |
| Adams, GE | 1 |
| Brown, JM; Yu, NY | 1 |
| Denekamp, J; Middleton, RW; Minchinton, AI; Rojas, A; Smith, KA; Soranson, JA | 1 |
| Biaglow, JE; Clark, EP; Epp, ER; Morse-Gaudio, M; Zachgo, E | 1 |
2 review(s) available for methionine sulfoximine and azomycin
| Article | Year |
|---|---|
Non-chemotherapeutic agents that potentiate chemotherapy efficacy.
Topics: Adult; Amphotericin B; Animals; Antimetabolites; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Buthionine Sulfoximine; Calcium Channel Blockers; Calmodulin; Cardiotonic Agents; Child; Clinical Trials as Topic; Dipyridamole; Drug Evaluation; Drug Resistance; Drug Synergism; Drug Therapy, Combination; Female; Humans; Ketoconazole; Male; Methionine Sulfoximine; Mice; Neoplasms; Nitroimidazoles; Xanthines | 1989 |
Biochemistry of reduction of nitro heterocycles.
Topics: Animals; Buthionine Sulfoximine; Catalase; Cell Division; Cell Survival; Etanidazole; Free Radicals; Glucose; Glutathione; Glycolysis; Hexosephosphates; Humans; Hypoxia; Methionine Sulfoximine; Microbodies; Microsomes; Misonidazole; Mitochondria; Nitroimidazoles; Oxidation-Reduction; Pentoses; Peroxidases; Sulfhydryl Compounds | 1986 |
1 trial(s) available for methionine sulfoximine and azomycin
| Article | Year |
|---|---|
Non-chemotherapeutic agents that potentiate chemotherapy efficacy.
Topics: Adult; Amphotericin B; Animals; Antimetabolites; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Buthionine Sulfoximine; Calcium Channel Blockers; Calmodulin; Cardiotonic Agents; Child; Clinical Trials as Topic; Dipyridamole; Drug Evaluation; Drug Resistance; Drug Synergism; Drug Therapy, Combination; Female; Humans; Ketoconazole; Male; Methionine Sulfoximine; Mice; Neoplasms; Nitroimidazoles; Xanthines | 1989 |
20 other study(ies) available for methionine sulfoximine and azomycin
| Article | Year |
|---|---|
Enhancement of SR 2508 (etanidazole) radiosensitization by buthionine sulphoximine at low-dose-rate irradiation.
Topics: Animals; Antimetabolites; Buthionine Sulfoximine; Cell Hypoxia; Dose-Response Relationship, Radiation; Drug Combinations; Drug Synergism; Etanidazole; In Vitro Techniques; Methionine Sulfoximine; Nitroimidazoles; Radiation-Sensitizing Agents | 1991 |
DNA damage induced in HT-29 colon cancer cells by exposure to 1-methyl-2-nitrosoimidazole, a reductive metabolite of 1-methyl-2-nitroimidazole.
Topics: Buthionine Sulfoximine; Colonic Neoplasms; DNA; DNA Damage; DNA, Neoplasm; Endopeptidase K; Humans; Hydrogen-Ion Concentration; Imidazoles; Methionine Sulfoximine; Nitroimidazoles; Nitroso Compounds; Oxidation-Reduction; Serine Endopeptidases; Tumor Cells, Cultured | 1991 |
Glutathione depletion and cytotoxicity of buthionine sulphoximine and SR2508 in rodent and human cells.
Topics: Animals; Antimetabolites; Buthionine Sulfoximine; Cell Line; Cell Survival; Cricetinae; Drug Synergism; Etanidazole; Glutathione; Humans; In Vitro Techniques; Methionine Sulfoximine; Nitroimidazoles; Radiation-Sensitizing Agents | 1990 |
Enhancement of melphalan (L-PAM) toxicity by reductive metabolites of 1-methyl-2-nitroimidazole, a model nitroimidazole chemosensitizing agent.
Topics: Buthionine Sulfoximine; Cell Survival; Drug Synergism; Glutathione; Humans; In Vitro Techniques; Melphalan; Methionine Sulfoximine; Nitroimidazoles; Oxidation-Reduction; Structure-Activity Relationship; Tumor Cells, Cultured | 1990 |
The effect of glutathione (GSH) depletion in vivo by buthionine sulfoximine (BSO) on the radiosensitization of SR 2508.
Topics: Animals; Buthionine Sulfoximine; Etanidazole; Glutathione; Methionine Sulfoximine; Mice; Mice, Inbred C3H; Neoplasms, Experimental; Nitroimidazoles; Radiation-Sensitizing Agents; Radiotherapy Dosage | 1989 |
Modification of SR 2508 sensitization in hypoxic V79 cells by manipulation of glutathione levels.
Topics: Animals; Buthionine Sulfoximine; Cell Line; Cell Survival; Cricetinae; Etanidazole; Glutathione; Methionine Sulfoximine; Nitroimidazoles; Oxygen; Pyrrolidonecarboxylic Acid; Radiation-Sensitizing Agents; Thiazoles; Thiazolidines | 1989 |
Role of glutathione in the susceptibility of Trypanosoma cruzi to drugs.
Topics: Animals; Antimetabolites; Buthionine Sulfoximine; Diazooxonorleucine; gamma-Glutamyltransferase; Glutathione; Glutathione Transferase; Methionine Sulfoximine; Nifurtimox; Nitrofurans; Nitroimidazoles; Trypanocidal Agents; Trypanosoma cruzi | 1989 |
Cytotoxicity and glutathione depletion by 1-methyl-2-nitrosoimidazole in human colon cancer cells.
Topics: Buthionine Sulfoximine; Cell Survival; Colonic Neoplasms; Glutathione; Humans; Methionine Sulfoximine; Nitroimidazoles; Tumor Cells, Cultured | 1989 |
Modulation of X ray DNA damage by SR-2508 +/- buthionine sulfoximine.
Topics: Animals; Buthionine Sulfoximine; Cell Line; Cricetinae; DNA; Drug Synergism; Etanidazole; Glutathione; In Vitro Techniques; Methionine Sulfoximine; Nitroimidazoles; Radiation-Sensitizing Agents | 1986 |
Enhancement in the aerobic toxicity of misonidazole and SR-2508 by buthionine sulfoximine and 4-hydroxypyrazole: the role of hydrogen peroxide.
Topics: Buthionine Sulfoximine; Cell Line; Cell Survival; Etanidazole; Glutathione; Humans; Hydrogen Peroxide; In Vitro Techniques; Methionine Sulfoximine; Misonidazole; Nitroimidazoles; Oxygen; Pyrazoles; Radiation-Sensitizing Agents | 1986 |
SR-2508 plus buthionine sulfoximine or SR-2508 alone: effects on the radiation response and the glutathione content of a human tumor xenograft.
Topics: Buthionine Sulfoximine; Cell Survival; Cysteine; Etanidazole; Glutathione; Humans; Methionine Sulfoximine; Neoplasm Transplantation; Neoplasms, Experimental; Nitroimidazoles; Radiation-Sensitizing Agents | 1987 |
Selective enhancement of hypoxic cell killing by melphalan via thiol depletion: in vitro studies with hypoxic cell sensitizers and buthionine sulfoximine.
Topics: Animals; Buthionine Sulfoximine; Cells, Cultured; Cricetinae; Cricetulus; Drug Synergism; Etanidazole; Melphalan; Methionine Sulfoximine; Misonidazole; Nitroimidazoles; Oxygen; Sulfhydryl Compounds | 1985 |
Combined effect of misonidazole and glutathione depletion by buthionine sulphoximine on cellular radiation response.
Topics: Animals; Buthionine Sulfoximine; Cell Line; Cricetinae; Cricetulus; DNA, Single-Stranded; Dose-Response Relationship, Drug; Fibroblasts; Glutathione; Humans; In Vitro Techniques; Methionine Sulfoximine; Misonidazole; Nitroimidazoles; Radiation Tolerance | 1985 |
Glutathione requirement for the rejoining of radiation-induced DNA breaks in misonidazole-treated cells.
Topics: Buthionine Sulfoximine; DNA; DNA Repair; DNA, Single-Stranded; Fibroblasts; Glutathione; Humans; Methionine Sulfoximine; Misonidazole; Nitroimidazoles; Radiation-Sensitizing Agents | 1985 |
Effects of glutathione depletion using buthionine sulphoximine on the cytotoxicity of nitroaromatic compounds in mammalian cells in vitro.
Topics: Animals; Buthionine Sulfoximine; Cells, Cultured; Cricetinae; Cricetulus; Glutathione; Methionine Sulfoximine; Misonidazole; Nitrofurantoin; Nitroimidazoles | 1985 |
Radiosensitizers: a conference preview.
Topics: Animals; Aziridines; Buthionine Sulfoximine; Carmustine; Combined Modality Therapy; Drug Synergism; Etanidazole; Humans; Ketones; Lomustine; Maleates; Methionine Sulfoximine; Mice; Misonidazole; Neoplasms; Nitroimidazoles; Radiation-Sensitizing Agents | 1984 |
Depletion of glutathione in vivo as a method of improving the therapeutic ratio of misonidazole and SR 2508.
Topics: Animals; Buthionine Sulfoximine; Combined Modality Therapy; Etanidazole; Glutathione; Maleates; Methionine Sulfoximine; Mice; Mice, Inbred Strains; Misonidazole; Neoplasm Transplantation; Neoplasms, Experimental; Nitroimidazoles; Radiation-Sensitizing Agents | 1984 |
Enhancement of misonidazole radiosensitization by buthionine sulphoximine.
Topics: Animals; Buthionine Sulfoximine; Combined Modality Therapy; Dose-Response Relationship, Radiation; Drug Synergism; Glutathione; Methionine Sulfoximine; Mice; Misonidazole; Neoplasm Transplantation; Neoplasms, Experimental; Nitroimidazoles; Radiation-Sensitizing Agents; Skin | 1984 |
Glutathione depletion, radiosensitization, and misonidazole potentiation in hypoxic Chinese hamster ovary cells by buthionine sulfoximine.
Topics: Animals; Buthionine Sulfoximine; Cell Survival; Cricetinae; Cricetulus; Dose-Response Relationship, Radiation; Drug Synergism; Female; Glutathione; Methionine Sulfoximine; Misonidazole; Nitroimidazoles; Ovary; Oxygen; Radiation-Sensitizing Agents; Time Factors | 1984 |
Enhancement of misonidazole radiosensitization by an inhibitor of glutathione biosynthesis.
Topics: Animals; Buthionine Sulfoximine; Cell Line; Cell Survival; Cricetinae; Cricetulus; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Drug Interactions; Glutathione; Methionine Sulfoximine; Misonidazole; Nitroimidazoles; Oxygen; Radiation Tolerance | 1983 |