methionine sulfoximine has been researched along with aspartic acid in 27 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (37.04) | 18.7374 |
| 1990's | 12 (44.44) | 18.2507 |
| 2000's | 2 (7.41) | 29.6817 |
| 2010's | 3 (11.11) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| De Robertis, E; Fiszer de Plazas, S; Sábato, UC | 1 |
| Alvey, TR; Brehe, JE; Burch, HB; Chan, AW | 1 |
| Beckstead, RM; Somers, DL | 2 |
| Ahluwalia, GS; Cooney, DA; Grem, JL; Hao, Z | 1 |
| Albrecht, J; Norenberg, MD | 1 |
| Baverel, G; Martin, G; Michoudet, C | 1 |
| Rothstein, JD; Tabakoff, B | 1 |
| Engelsen, B; Fonnum, F; Fosse, VM; Paulsen, RH | 1 |
| Fontenelle, LJ; Henderson, JF | 1 |
| Haldeman, S; McLennan, H | 1 |
| Davies, J; Watkins, JC | 1 |
| Brown, DJ; Stone, WE | 1 |
| Meister, A | 1 |
| Massieu, GH; Ortega, BG; Pasantes, H; Pérez de la Mora, M; Tapia, R | 1 |
| Bryła, J; Lietz, T | 1 |
| Bates, TE; Clark, JB; Davies, SE; Heales, SJ | 1 |
| McBean, GJ | 1 |
| Aschner, M; Kimelberg, HK; Lash, LH; Mullaney, KJ; Wagoner, D | 1 |
| Exposito, I; Mora, F; Porras, A; Sanz, B | 1 |
| Bender, AS; White, HS; Woodbury, DM | 1 |
| Crespo, JL; Florencio, FJ; Guerrero, MG | 1 |
| Attwell, D; Grant, J; Marcaggi, P; Mort, D | 1 |
| Ishikawa, M; Izumi, Y; Yoshitomi, T; Zorumski, CF | 1 |
| Ahn, DK; Bae, YC; Ju, JS; Kim, MJ; Kim, ST; Mun, JH; Park, KD; Yang, KY | 1 |
| Cohen, A; Kupiec, M; Reidman, S; Weisman, R | 1 |
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
2 review(s) available for methionine sulfoximine and aspartic acid
| Article | Year |
|---|---|
Metabolism and action of amino acid analog anti-cancer agents.
Topics: Amino Acids; Animals; Antineoplastic Agents; Aspartic Acid; Buthionine Sulfoximine; Eflornithine; Glutamine; Humans; Methionine Sulfoximine | 1990 |
The specificity of glutamine synthetase and its relationship to substrate conformation at the active site.
Topics: Amino Acids; Ammonia; Aspartic Acid; Binding Sites; Cyclohexanes; Glutamates; Glutamine; Ligases; Methionine Sulfoximine; Models, Chemical | 1968 |
25 other study(ies) available for methionine sulfoximine and aspartic acid
| Article | Year |
|---|---|
The convulsant drugs 3-mercaptopropionate and methionine sulfoximine inhibit L-glutamate and L-aspartate binding to a hydrophobic protein fraction from rat cerebral cortex.
Topics: 3-Mercaptopropionic Acid; Animals; Aspartic Acid; Glutamates; Methionine Sulfoximine; Proteolipids; Radioligand Assay; Rats; Sulfhydryl Compounds | 1979 |
Effect of methionine sulfoximine on glutathione and amino acid levels in the nephron.
Topics: Amino Acids, Dicarboxylic; Animals; Aspartic Acid; Glutamates; Glutamine; Glutathione; Kidney; Kidney Cortex; Kidney Glomerulus; Kidney Medulla; Kidney Tubules; Male; Methionine Sulfoximine; Nephrons; Rats | 1976 |
Striatal preprotachykinin and preproenkephalin mRNA levels and the levels of nigral substance P and pallidal Met5-enkephalin depend on corticostriatal axons that use the excitatory amino acid neurotransmitters aspartate and glutamate: quantitative radioim
Topics: Animals; Aspartic Acid; Axons; Brain Chemistry; Cerebral Cortex; Corpus Striatum; Enkephalins; Gene Expression Regulation; Globus Pallidus; Glutamate-Ammonia Ligase; Glutamates; Glutamic Acid; Male; Methionine Sulfoximine; Neurotransmitter Agents; Nucleic Acid Hybridization; Protein Precursors; Rats; Rats, Inbred Strains; RNA, Messenger; Substance P; Substantia Nigra; Synaptic Transmission; Tachykinins | 1990 |
Chronic methionine sulfoximine administration reduces synaptosomal aspartate and glutamate in rat striatum.
Topics: Animals; Aspartic Acid; Brain; Corpus Striatum; Enzyme Inhibitors; Glutamates; Glutamic Acid; Male; Methionine Sulfoximine; Neurotransmitter Agents; Rats; Rats, Inbred Strains; Synaptosomes | 1990 |
L-methionine-DL-sulfoximine induces massive efflux of glutamine from cortical astrocytes in primary culture.
Topics: Animals; Animals, Newborn; Aspartic Acid; Astrocytes; Bucladesine; Cells, Cultured; Cerebral Cortex; gamma-Aminobutyric Acid; Glutamine; Methionine Sulfoximine; Rats | 1990 |
Glutamine synthesis from aspartate in guinea-pig renal cortex.
Topics: Aminooxyacetic Acid; Ammonium Chloride; Animals; Aspartate Aminotransferases; Aspartic Acid; Carbon Radioisotopes; Coumaric Acids; Fluoroacetates; Glutamate Dehydrogenase; Glutamine; Guinea Pigs; Kidney Tubules; Methionine Sulfoximine; Nitrogen; Oxaloacetates; Quinolinic Acids | 1990 |
Regulation of neurotransmitter aspartate metabolism by glial glutamine synthetase.
Topics: Analysis of Variance; Animals; Aspartic Acid; Glutamate-Ammonia Ligase; Glutamine; Male; Methionine Sulfoximine; Neuroglia; Rats; Rats, Inbred Strains | 1986 |
Synthesis and release of amino acid transmitters.
Topics: Animals; Aspartic Acid; Brain; Citrates; Corpus Striatum; gamma-Aminobutyric Acid; Glutamates; Hypoglycemia; Ketoglutaric Acids; Methionine Sulfoximine; Trifluoperazine | 1986 |
Sources of nitrogen as rate-limiting factors for purine biosynthesis de novo in Ehrlich ascites tumor cells.
Topics: Adenine; Ammonia; Animals; Asparagine; Aspartic Acid; Carbon Isotopes; Carcinoma, Ehrlich Tumor; Diphosphates; Drug Synergism; Glutamine; Glycine; Hypoxanthines; Kinetics; Ligases; Methionine Sulfoximine; Nitrogen; Nucleotides; Pentosephosphates; Purines; Transferases | 1969 |
The antagonistic action of glutamic acid diethylester towards amino acid-induced and synaptic excitations of central neurones.
Topics: Action Potentials; Amino Acids; Animals; Aspartic Acid; Cats; Cysteine; Electric Stimulation; Esters; Excitatory Amino Acid Antagonists; Glutamates; Homocysteine; Interneurons; Iontophoresis; Medulla Oblongata; Methionine Sulfoximine; Spinal Cord; Synaptic Transmission; Thalamic Nuclei; Thalamus | 1972 |
Microelectrophoretic studies on the depressant action of HA-966 on chemically and synaptically excited neurones in the cat cerebral cortex and cuneate nucleus.
Topics: Acetylcholine; Alkaloids; Amines; Aminobutyrates; Animals; Aspartic Acid; Cats; Cerebral Cortex; Depression, Chemical; Dioxoles; Esters; Glutamates; Glycine; Hydroxamic Acids; Isoquinolines; Medulla Oblongata; Methionine Sulfoximine; Neurons; Pentobarbital; Pyrrolidinones; Strychnine; Synaptic Transmission | 1973 |
Glutamate and aspartate in cortical subarachnoid fluid in relation to convulsive activity.
Topics: Animals; Aspartic Acid; Azoles; Brain; Dogs; Glutamates; Methionine Sulfoximine; Picrotoxin; Seizures; Subarachnoid Space; Thiosemicarbazones | 1973 |
Free amino acids and glutamate decarboxylase activity in brain of mice during drug-induced convulsions.
Topics: Alanine; Aminobutyrates; Animals; Aspartic Acid; Brain Chemistry; Carboxy-Lyases; Glutamates; Glutamine; Hydrazines; Insulin; Methionine; Methionine Sulfoximine; Mice; Pentylenetetrazole; Pyridoxal Phosphate; Seizures; Thiosemicarbazones; Transaminases | 1967 |
Glycerol and lactate induce reciprocal changes in glucose formation and glutamine production in isolated rabbit kidney-cortex tubules incubated with aspartate.
Topics: Amino Acids; Ammonia; Animals; Aspartic Acid; Gluconeogenesis; Glucose; Glutamine; Glycerol; In Vitro Techniques; Kidney Cortex; Kidney Tubules; Kinetics; Lactates; Lactic Acid; Methionine Sulfoximine; Models, Biological; Rabbits | 1995 |
Depletion of brain glutathione is accompanied by impaired mitochondrial function and decreased N-acetyl aspartate concentration.
Topics: Animals; Aspartic Acid; Brain; Buthionine Sulfoximine; Glutathione; Methionine Sulfoximine; Mitochondria; Neurons; Rats | 1995 |
Inhibition of the glutamate transporter and glial enzymes in rat striatum by the gliotoxin, alpha aminoadipate.
Topics: 2-Aminoadipic Acid; Amino Acid Transport System X-AG; Animals; Aspartic Acid; Biological Transport; Cell Membrane; Glutamate-Ammonia Ligase; Glutamate-Cysteine Ligase; Glycoproteins; In Vitro Techniques; Kinetics; Methionine Sulfoximine; Neostriatum; Neuroglia; Rats; Sodium; Stereoisomerism; Synaptosomes | 1994 |
Intracellular glutathione (GSH) levels modulate mercuric chloride (MC)- and methylmercuric chloride (MeHgCl)-induced amino acid release from neonatal rat primary astrocytes cultures.
Topics: Animals; Animals, Newborn; Aspartic Acid; Astrocytes; Buthionine Sulfoximine; Cells, Cultured; Glutamate-Cysteine Ligase; Glutathione; Mercuric Chloride; Methionine Sulfoximine; Methylmercury Compounds; Pyrrolidonecarboxylic Acid; Rats; Rats, Sprague-Dawley; Stimulation, Chemical; Taurine; Thiazoles; Thiazolidines; Tritium | 1994 |
Effects of apomorphine and L-methionine sulphoximine on the release of excitatory amino acid neurotransmitters and glutamine in the striatum of the conscious rat.
Topics: Analysis of Variance; Animals; Apomorphine; Aspartic Acid; Corpus Striatum; Glutamates; Glutamic Acid; Glutamine; Haloperidol; Kinetics; Male; Methionine Sulfoximine; Neurotransmitter Agents; Rats; Rats, Wistar; Receptors, Dopamine D1; Receptors, Dopamine D2 | 1994 |
The rapid L- and D-aspartate uptake in cultured astrocytes.
Topics: Aminooxyacetic Acid; Animals; Aspartate Aminotransferases; Aspartic Acid; Astrocytes; Biological Transport; Cells, Cultured; Energy Metabolism; Enzyme Inhibitors; Glutamate-Ammonia Ligase; Iodoacetates; Iodoacetic Acid; Methionine Sulfoximine; Mice; Rotenone; Stereoisomerism; Time Factors | 1997 |
Mutational analysis of Asp51 of Anabaena azollae glutamine synthetase. D51E mutation confers resistance to the active site inhibitors L-methionine-DL-sulfoximine and phosphinothricin.
Topics: Amino Acid Sequence; Aminobutyrates; Anabaena; Aspartic Acid; Base Sequence; Catalytic Domain; Cloning, Molecular; DNA Primers; Enzyme Inhibitors; Escherichia coli; Genes, Bacterial; Genetic Complementation Test; Glutamate-Ammonia Ligase; Herbicides; Kinetics; Methionine Sulfoximine; Molecular Sequence Data; Mutagenesis, Site-Directed; Point Mutation; Sequence Homology, Amino Acid | 1999 |
Effect of acute exposure to ammonia on glutamate transport in glial cells isolated from the salamander retina.
Topics: Amino Acid Transport System X-AG; Ammonia; Animals; Anions; Aspartic Acid; ATP-Binding Cassette Transporters; Cell Separation; Glutamate-Ammonia Ligase; Glutamic Acid; Hydrogen-Ion Concentration; Ion Channel Gating; Membrane Potentials; Methionine Sulfoximine; Neuroglia; Patch-Clamp Techniques; Potassium; Quaternary Ammonium Compounds; Retina; Sodium; Urodela | 2001 |
Downregulation of glutamine synthetase via GLAST suppression induces retinal axonal swelling in a rat ex vivo hydrostatic pressure model.
Topics: Animals; Aspartic Acid; Axons; Blotting, Western; Disease Models, Animal; Down-Regulation; Excitatory Amino Acid Transporter 1; Fluorescent Antibody Technique, Indirect; Glutamate-Ammonia Ligase; Glutamic Acid; Hydrostatic Pressure; Male; Methionine Sulfoximine; Rats; Rats, Sprague-Dawley; Retinal Degeneration; Retinal Ganglion Cells; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2011 |
Blockade of spinal glutamate recycling produces paradoxical antinociception in rats with orofacial inflammatory pain.
Topics: Amino Acid Transport System X-AG; Animals; Aspartic Acid; Astrocytes; Botulinum Toxins, Type A; Facial Pain; Freund's Adjuvant; Glutamate-Ammonia Ligase; Glutamic Acid; Hyperalgesia; Injections, Intraventricular; Interleukin-1beta; Male; Methionine Sulfoximine; Nociception; Rats; Spinal Cord Dorsal Horn | 2015 |
The cytosolic form of aspartate aminotransferase is required for full activation of TOR complex 1 in fission yeast.
Topics: Arginine; Asparagine; Aspartate Aminotransferases; Aspartic Acid; Cytosol; Gene Expression Regulation, Fungal; Isoenzymes; Mechanistic Target of Rapamycin Complex 1; Methionine Sulfoximine; Mutation; Nitrogen; Schizosaccharomyces; Schizosaccharomyces pombe Proteins; Sirolimus | 2019 |
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |